G. Guichard

发表

Hybrid Cell-Penetrating Foldamer with Superior Intracellular Delivery Properties and Serum Stability.

A. Kichler, C. Douat, Mégane Bornerie, 2019, Bioconjugate chemistry.

N-Heterocyclic Carbene-Polyethylenimine Platinum Complexes with Potent in Vitro and in Vivo Antitumor Efficacy.

G. Gasser, S. Fournel, G. Guichard, 2016, Bioconjugate chemistry.

A cell-penetrating foldamer with a bioreducible linkage for intracellular delivery of DNA.

A. Kichler, C. Douat, Stéphanie Antunes, 2015, Angewandte Chemie.

In silico-guided target identification of a scaffold-focused library: 1,3,5-triazepan-2,6-diones as novel phospholipase A2 inhibitors.

Didier Rognan, Pascal Muller, Eric Boilard, 2006, Journal of medicinal chemistry.

Efficient Binding of Reduced Peptide Bond Pseudopeptides to Major Histocompatibility Complex Class I Molecule (*)

P. Kourilsky, J. Abastado, J. Briand, 1995, The Journal of Biological Chemistry.

Foldamers in Medicinal Chemistry

G. Guichard, M. Pasco, C. Dolain, 2017, Comprehensive Supramolecular Chemistry II.

Efficient synthesis of (S)-4-phthalimido-1,3,4,5-tetrahydro-8-(2,6-dichlorobenzyloxy)- 3-oxo-2H-2-benzazepin-2-acetic acid (PHt-Hba(2,6-Cl2-Bn)-Gly-OH).

J. Briand, G. Guichard, D. Tourwé, 2000, The Journal of organic chemistry.

Exploring helical folding of oligoureas during chain elongation by high-resolution magic-angle-spinning (HRMAS) NMR spectroscopy.

K. Elbayed, A. Bianco, J. Briand, 2008, Chemistry.

Solution structure determination of oligoureas using methylene spin state selective NMR at 13C natural abundance

E. Miclet, G. Guichard, G. Chassaing, 2008, Magnetic resonance in chemistry : MRC.

Solid state NMR studies of oligourea foldamers: interaction of 15N-labelled amphiphilic helices with oriented lipid membranes.

G. Guichard, C. Aisenbrey, B. Bechinger, 2012, Organic & biomolecular chemistry.

Antigenic mimicry of natural L-peptides with retro-inverso-peptidomimetics.

M. V. Van Regenmortel, S. Muller, J. Briand, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Structural limitations to antigenic mimicry achievable with retroinverso (all-D-retro) peptides.

E. Giralt, M. V. Van Regenmortel, S. Muller, 1996, Trends in biotechnology.

Stabilization of an α-helix by short adjacent accessory foldamers

G. Guichard, B. Kauffmann, B. Odaert, 2016 .

An activated building block for the introduction of the histidine side chain in aliphatic oligourea foldamers

C. Didierjean, G. Guichard, Céline Douat-Casassus, 2012 .

The V3 loop-mimicking pseudopeptide 5[Kpsi(CH2N)PR]-TASP inhibits HIV infection in primary macrophage cultures.

S. Nisole, S. Muller, J. Briand, 1999, AIDS research and human retroviruses.

Solid‐Phase Synthesis of Hybrid Urea Oligomers Containing Conservative Thiourea Mutations

C. Douat, Stéphanie Antunes, G. Guichard, 2016 .

Synthesis and folding propensity of aliphatic oligoureas containing repeats of proline-type units.

G. Guichard, B. Kauffmann, Juliette Fremaux, 2014, The Journal of organic chemistry.

Trypanosoma cruzi Experimental during γ and Enhance T Cells Producing IFN-Mimetics Promote Control of Parasitemia Cutting Edge : Small Molecule CD 40 Ligand

M. Goldman, H. Dumortier, A. Bianco, 2007 .

Cutting Edge: Small Molecule CD40 Ligand Mimetics Promote Control of Parasitemia and Enhance T Cells Producing IFN-γ during Experimental Trypanosoma cruzi Infection1

M. Goldman, H. Dumortier, A. Bianco, 2007, Journal of Immunology.

C3-symmetric peptide scaffolds are functional mimetics of trimeric CD40L

R. Offringa, C. Melief, P. Schneider, 2005, Nature chemical biology.

Rationally-designed multivalent architectures for mimicking homotrimers of CD40L, a member of the TNF superfamily.

P. Schneider, A. Bianco, S. Fournel, 2009, Advances in experimental medicine and biology.

Relationship between the agonist activity of synthetic ligands of TRAIL-R2 and their cell surface binding modes

D. Altschuh, Y. Nominé, C. M. Lombardo, 2018, Oncotarget.

A Chemoselective and Modular Post‐Synthetic Multi‐Functionalization of NHC–Platinum Complexes

G. Guichard, G. Dahm, S. Bellemin‐Laponnaz, 2015 .

Development of a practical solid-phase synthesis approach to 1,3,5-triazepan-2,6-diones

G. Guichard, J. Boeglin, Claire Venin, 2012 .

5-(3,4-Dimethoxybenzyl)-7-isopropyl-1,3,5-triazepane-2,6-dione acetonitrile solvate refined using a multipolar atom model.

C. Didierjean, C. Jelsch, G. Guichard, 2010, Acta crystallographica. Section C, Crystal structure communications.

Control of duplex formation and columnar self-assembly with heterogeneous amide/urea macrocycles.

C. Didierjean, J. Briand, G. Guichard, 2009, Angewandte Chemie.

7-Isopropyl-5-methyl-1,3,5-triazepan-2,6-dione deuterated chloroform 0.94-solvate

C. Didierjean, G. Guichard, G. Lena, 2007 .

α-Peptide-Oligourea Chimeras: Stabilization of Short α-Helices by Non-Peptide Helical Foldamers.

G. Guichard, B. Kauffmann, B. Odaert, 2015, Angewandte Chemie.

Easy Derivatisation of Group 10 N-Heterocyclic Carbene Complexes and In Vitro Evaluation of an Anticancer Oestradiol Conjugate

G. Puleo, S. Fournel, G. Guichard, 2012 .

Insights into spatial configuration of a galactosylated epitope required to trigger arthritogenic T-cell receptors specific for the sugar moiety

J. Briand, G. Guichard, G. Chiocchia, 2007, Arthritis research & therapy.

Synthesis of Glycopeptides from Type II Collagen‐Incorporating Galactosylated Hydroxylysine Mimetics and Their Use in Studying the Fine Specificity of Arthritogenic T Cells

J. Briand, G. Guichard, G. Chiocchia, 2005, Chembiochem : a European journal of chemical biology.

Native ESI Mass Spectrometry Can Help to Avoid Wrong Interpretations from Isothermal Titration Calorimetry in Difficult Situations

P. Dumas, G. Guichard, G. Bec, 2016, Journal of The American Society for Mass Spectrometry.

Partially modified retro-inverso pseudopeptides as non-natural ligands for the human class I histocompatibility molecule HLA-A2.

S. Muller, J. Briand, G. Guichard, 1996, Journal of medicinal chemistry.

Direct functionalisation of group 10 N-heterocyclic carbene complexes for diversity enhancement.

G. Puleo, G. Guichard, G. Dahm, 2011, Chemical communications.

Helical Oligourea Foldamers as Powerful Hydrogen Bonding Catalysts for Enantioselective C-C Bond-Forming Reactions.

G. Guichard, B. Kauffmann, C. Palomo, 2017, Journal of the American Chemical Society.

Synthetic ligands of death receptor 5 display a cell-selective agonistic effect at different oligomerization levels

C. M. Lombardo, C. Smulski, J. Beyrath, 2016, Oncotarget.

Role of peptide backbone in T cell recognition.

P. Kourilsky, J. Abastado, P. Bousso, 1999, Journal of immunology.

Identification of V3 Loop-binding Proteins as Potential Receptors Implicated in the Binding of HIV Particles to CD4+Cells*

E. Dam, J. Blanco, S. Muller, 1998, The Journal of Biological Chemistry.

Porous 3-D honeycomb architecture by self-assembly of helical H-bonded molecular tapes.

A. Aubry, C. Didierjean, J. Briand, 2006, Chemical communications.

Unexpected stability of the urea cis-trans isomer in urea-containing model pseudopeptides.

A. Aubry, C. Didierjean, J. Briand, 2001, Organic letters.

A partially modified retro-inverso pseudopeptide modulates the cytokine profile of CTL specific for an influenza virus epitope.

S. Muller, J. Briand, J. Hoebeke, 1998, Journal of immunology.

CTL Specific for an Influenza Virus Epitope Pseudopeptide Modulates the Cytokine Profile of A Partially Modified Retro-Inverso

S. Muller, J. Briand, J. Hoebeke, 1998 .

Antigen-based T-cell-targeted immunotherapy: recent developments in autoimmunity and allergy

G. Guichard, C. Stemmer, 1998 .

Multistep synthesis of 2,5-diketopiperazines on different solid supports monitored by high resolution magic angle spinning NMR spectroscopy.

J. Furrer, K. Elbayed, A. Bianco, 2000, Journal of combinatorial chemistry.

Review Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis MHC ligands as potential therapeutics in the treatment of autoimmune and allergic diseases

G. Guichard, 1997 .

MHC ligands as potential therapeutics in the treatment of autoimmune and allergic diseases

G. Guichard, 1997 .

Melanoma peptide MART-1(27-35) analogues with enhanced binding capacity to the human class I histocompatibility molecule HLA-A2 by introduction of a beta-amino acid residue: implications for recognition by tumor-infiltrating lymphocytes.

J. Briand, J. Hoebeke, G. Guichard, 2000, Journal of medicinal chemistry.

10‐Methyl‐8,9,10,11,11a,12‐hexahydro‐5H,7H‐isoquinolino[3,2‐g][1,3,5]triazepine‐7,11‐dione

C. Didierjean, G. Guichard, G. Lena, 2006 .

tert-Butyl (6S)-4-hydroxy-6-isobutyl-2-oxo-1,2,5,6-tetrahydropyridine-1-carboxylate and tert-butyl (4R,6S)-4-hydroxy-6-isobutyl-2-oxopiperidine-1-carboxylate.

A. Aubry, C. Didierjean, J. Briand, 2004, Acta crystallographica. Section C, Crystal structure communications.

(6S)-6-Isobutylpiperidine-2,4-dione and (4R,6S)/(4S,6S)-4-hydroxy-6-isobutylpiperidin-2-one.

A. Aubry, C. Didierjean, J. Briand, 2004, Acta crystallographica. Section C, Crystal structure communications.

(S)-O-Succinimidyl N-[2-(tert-butoxycarbonylamino)propyl]carbamate

A. Aubry, C. Didierjean, J. Briand, 2001 .

The anti-HIV pentameric pseudopeptide HB-19 is preferentially taken up in vivo by lymphoid organs where it forms a complex with nucleolin

E. Jacotot, J. Briand, C. Rougeot, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Pseudopeptide TASP Inhibitors of HIV Entry Bind Specifically to a 95-kDa Cell Surface Protein*

E. Jacotot, J. Briand, G. Guichard, 1997, The Journal of Biological Chemistry.

Formation and Modulation of Nanotubular Assemblies of Oligourea Foldamers in Aqueous Conditions using Alcohol Additives.

Sung Hyun Yoo, G. Guichard, G. Collie, 2020, ChemPlusChem.

Peptide analogues as vaccines and immunomodulators

M. V. Regenmortel, S. Muller, H. Dumortier, 1999 .

Antitumor vaccination using a major histocompatibility complex (MHC) class I-restricted pseudopeptide with reduced peptide bond.

P. Kourilsky, J. Abastado, S. Muller, 2000, Journal of immunotherapy.

Anatomy of an Oligourea Six-Helix Bundle.

G. Guichard, Cameron D. Mackereth, F. Rosu, 2016, Journal of the American Chemical Society.

Synthesis of a Galactosylated 4‐Hydroxylysine Building Block and Its Incorporation into a Collagen Immunodominant Glycopeptide

J. Briand, G. Guichard, J. Marin, 2008 .

Effect of replacing main-chain ureas with thiourea and guanidinium surrogates on the bactericidal activity of membrane active oligourea foldamers.

C. Douat, Stéphanie Antunes, G. Guichard, 2017, Bioorganic & medicinal chemistry.

Proteolytically Stable Foldamer Mimics of Host-Defense Peptides with Protective Activities in a Murine Model of Bacterial Infection.

C. Rougeot, C. Douat, Stéphanie Antunes, 2016, Journal of medicinal chemistry.

Optimal Anchoring of a Urea-based Foldamer Inhibitor of ASF1 Histone Chaperone Through Backbone Plasticity

R. Guérois, F. Ochsenbein, C. Douat, 2020 .

Do Bioactive Peptides Display Native-Like Conformations When Bound to a Solid Support?

J. Furrer, K. Elbayed, A. Bianco, 2001 .

The potential of retro-inverso peptides as synthetic vaccines.

M. V. Van Regenmortel, F. Brown, S. Muller, 1998, Developments in biological standardization.

(S)-β3-Homolysine- and (S)-β3-Homoserine-Containingβ-Peptides: CD Spectra in Aqueous Solution

D. Seebach, G. Guichard, Stefan Abele, 1998 .

Foldamers Based on Remote Intrastrand Interactions

G. Guichard, P. Grel, 2007 .

Experimental and theoretical study of the vibrational spectra of oligoureas: helical versus β-sheet-type secondary structures.

D. Cavagnat, B. Desbat, G. Guichard, 2011, The journal of physical chemistry. B.

Folding and self-assembly of aromatic and aliphatic urea oligomers: towards connecting structure and function.

G. Guichard, Lucile Fischer, 2010, Organic & biomolecular chemistry.

Design of Oligourea-Based Foldamers with Antibacterial and Antifungal Activities

P. Lavalle, B. Frisch, A. Kichler, 2022, Molecules.

The canonical helix of urea oligomers at atomic resolution: insights into folding-induced axial organization.

C. Didierjean, E. Miclet, G. Guichard, 2009, Angewandte Chemie.

N,N'-linked oligoureas as foldamers: chain length requirements for helix formation in protic solvent investigated by circular dichroism, NMR spectroscopy, and molecular dynamics.

D. Rognan, R. Casimir, J. Briand, 2005, Journal of the American Chemical Society.

Stable helical secondary structure in short-chain N,N'-linked oligoureas bearing proteinogenic side chains.

D. Rognan, J. Briand, G. Guichard, 2002, Angewandte Chemie.

Solid phase synthesis of oligoureas using O-succinimidyl-(9H-fluoren-9-ylmethoxycarbonylamino)ethylcarbamate derivatives as activated monomers

J. Briand, G. Guichard, V. Semetey, 2000 .

Effective Preparation of O-Succinimidyl-2- (tert-butoxycarbonylamino)ethylcarbamate Derivatives from β-Amino Acids. Application to the Synthesis of Urea-Containing Pseudopeptides and Oligoureas†

A. Aubry, C. Didierjean, J. Briand, 1999 .

Preparation of N-Fmoc-Protected β2- and β3-Amino Acids and their use as building blocks for the solid-phase synthesis of β-peptides†‡

D. Seebach, G. Guichard, Stefan Abele, 1998 .

Antigenicity and immunogenicity of modified synthetic peptides containing D-amino acid residues. Antibodies to a D-enantiomer do recognize the parent L-hexapeptide and reciprocally.

S. Muller, J. Briand, G. Guichard, 1993, The Journal of biological chemistry.

Rapid Procedure for N-Phthaloylation of α-Amino Carboxamides, α-Amino Alcohols, α-Amino Esters and Dipeptide Derivatives

J. Briand, G. Guichard, D. Tourwé, 2001 .

Exploring nitrogen ligand diversity in trans-N-heterocyclic carbene-amine platinum complexes: synthesis, characterization, and application to fluorescence.

G. Guichard, G. Dahm, S. Bellemin‐Laponnaz, 2013, Chemistry, an Asian journal.

Post-functionalization of platinum–NHC complexes by oxime ligation for ligand targeted therapy

G. Guichard, G. Dahm, S. Bellemin‐Laponnaz, 2016 .

Proline-rich antimicrobial peptides targeting protein synthesis.

Daniel N. Wilson, M. Graf, C. Innis, 2017, Natural product reports.

Mimicking helical antibacterial peptides with nonpeptidic folding oligomers.

S. Fournel, J. Briand, O. Chaloin, 2006, Chemistry & biology.

Synthesis of enantiopure 4-hydroxypipecolate and 4-hydroxylysine derivatives from a common 4,6-dioxopiperidinecarboxylate precursor.

C. Didierjean, J. Briand, G. Guichard, 2004, The Journal of organic chemistry.

Molecular Recognition within the Cavity of a Foldamer Helix Bundle: Encapsulation of Primary Alcohols in Aqueous Conditions.

G. Guichard, Cameron D. Mackereth, Rémy Bailly, 2017, Journal of the American Chemical Society.

Shaping quaternary assemblies of water-soluble non-peptide helical foldamers by sequence manipulation.

G. Guichard, M. Decossas, O. Lambert, 2015, Nature chemistry.

1,3,5-Triazepane-2,6-diones as structurally diverse and conformationally constrained dipeptide mimetics: identification of malaria liver stage inhibitors from a small pilot library.

A. Aubry, L. Rénia, C. Didierjean, 2006, Chemistry.

β2‐ and β3‐Peptides with Proteinaceous Side Chains: Synthesis and solution structures of constitutional isomers, a novel helical secondary structure and the influence of solvation and hydrophobic interactions on folding

B. Jaun, D. Seebach, K. Gademann, 1998 .

Aza-beta3-cyclopeptides: a new way of controlling nitrogen chirality.

G. Guichard, M. Potel, B. Jamart-Grégoire, 2009, Journal of the American Chemical Society.

Inducing achiral aliphatic oligoureas to fold into helical conformations.

G. Guichard, J. Clayden, Scott P. France, 2014, Chemical communications.

Synthesis of Enantiopure Di(Tert‐Butyl) (2S,4S)‐4‐Hydroxy‐6‐Oxo‐1,2‐Piperidinedicarboxylate. A Useful Building Block for the Preparation of 4‐Hydroxypipecolate Derivatives

O. Chaloin, G. Guichard, J. Marin, 2008 .

Diastereoselective hydroxylation of 6-substituted piperidin-2-ones. An efficient synthesis of (2S,5R)-5-hydroxylysine and related alpha-amino acids.

C. Didierjean, J. Briand, G. Guichard, 2002, The Journal of organic chemistry.

Anion Recognition by Aliphatic Helical Oligoureas.

G. Guichard, B. Kauffmann, V. Diemer, 2016, Chemistry.

Synthetic foldamers.

Ivan Huc, G. Guichard, I. Huc, 2011, Chemical communications.

Anion-macrodipole interactions: self-assembling oligourea/amide macrocycles as anion transporters that respond to membrane polarization.

S. Matile, G. Guichard, A. Hennig, 2009, Journal of the American Chemical Society.

Consequences of isostructural main-chain modifications for the design of antimicrobial foldamers: helical mimics of host-defense peptides based on a heterogeneous amide/urea backbone.

Guy Duportail, Yves Mély, Y. Mély, 2010, Angewandte Chemie.

Propensity for local folding induced by the urea fragment in short-chain oligomers.

C. Didierjean, J. Briand, G. Guichard, 2008, Organic & biomolecular chemistry.

Stabilized helical peptides: overview of the technologies and therapeutic promises

G. Guichard, K. Estieu-Gionnet, 2011, Expert opinion on drug discovery.

Self-assembling organic nanotubes from enantiopure cyclo-N,N'-linked oligoureas: design, synthesis, and crystal structure.

A. Aubry, C. Didierjean, J. Briand, 2002, Angewandte Chemie.

Succinimidyl Carbamate Derivatives from N‐Protected α‐Amino Acids and Dipeptides―Synthesis of Ureidopeptides and Oligourea/Peptide Hybrids

C. Didierjean, J. Lozano, J. Briand, 2007 .

Controlling helix formation in the γ-peptide superfamily: heterogeneous foldamers with urea/amide and urea/carbamate backbones.

M. Laguerre, C. Douat, G. Guichard, 2013, Angewandte Chemie.

Surfactant-facilitated crystallisation of water-soluble foldamers† †Electronic supplementary information (ESI) available: Detailed experimental procedures, additional figures and tables describing structures as well as crystallography details. CCDC 1050867–1050870. For ESI and crystallographic data

G. Guichard, G. Collie, K. Pułka-Ziach, 2016, Chemical Science.

Isosteric substitutions of urea to thiourea and selenourea in aliphatic oligourea foldamers: site-specific perturbation of the helix geometry.

C. Douat, Stéphanie Antunes, G. Guichard, 2015, Chemistry.

Influence of achiral units with gem-dimethyl substituents on the helical character of aliphatic oligourea foldamers.

G. Guichard, B. Kauffmann, C. Dolain, 2013, Chemical communications.

Structural basis for α-helix mimicry and inhibition of protein-protein interactions with oligourea foldamers.

N. Rochel, J. Ősz, G. Guichard, 2020, Angewandte Chemie.

Helix-Forming Oligoureas: Temperature-Dependent NMR, Structure Determination, and Circular Dichroism of a Nonamer with Functionalized Side Chains

D. Rognan, J. Briand, G. Guichard, 2002 .

Structural characterization of short hybrid urea/carbamate (U/C) foldamers: A case of partial helix unwinding.

G. Guichard, B. Kauffmann, G. Collie, 2013, Biopolymers.

Helix-forming propensity of aliphatic urea oligomers incorporating noncanonical residue substitution patterns.

M. Laguerre, D. Cavagnat, B. Desbat, 2013, Journal of the American Chemical Society.

Condensation approach to aliphatic oligourea foldamers: helices with N-(pyrrolidin-2-ylmethyl)ureido junctions.

G. Guichard, B. Kauffmann, T. Arbogast, 2011, Angewandte Chemie.

The meso Helix: Symmetry and Symmetry-Breaking in Dynamic Oligourea Foldamers with Reversible Hydrogen-Bond Polarity.

D. Cavagnat, G. Guichard, J. Raftery, 2016, Angewandte Chemie.

A chiral thiourea and a phosphazene for fast and stereoselective organocatalytic ring-opening-polymerization of racemic lactide.

M. Zaky, D. Taton, G. Guichard, 2021, Chemical communications.

Peptide-oligourea hybrids analogue of GLP-1 with improved action in vivo

G. Guichard, L. Mauran, Juliette Fremaux, 2019, Nature Communications.

Microwave-enhanced solid-phase synthesis of N,N'-linked aliphatic oligoureas and related hybrids.

G. Guichard, Céline Douat-Casassus, P. Claudon, 2012, Organic letters.

Design and Structure Determination of a Composite Zinc Finger Containing a Nonpeptide Foldamer Helical Domain.

G. Salgado, J. Mergny, C. Douat, 2019, Journal of the American Chemical Society.

DEUSS: a perdeuterated poly(oxyethylene)-based resin for improving HRMAS NMR studies of solid-supported molecules.

K. Elbayed, A. Bianco, J. Briand, 2004, Chemistry.

Calculations on the electronic excited states of ureas and oligoureas.

Mark T. Oakley, J. Hirst, G. Guichard, 2007, The journal of physical chemistry. B.

Mixing urea and amide bonds: synthesis and self-organization of new hybrid oligomers.

C. Didierjean, J. Briand, G. Guichard, 2009, Advances in experimental medicine and biology.

Parameters Influencing Helix Stability of Oligourea Foldamers

D. Rognan, J. Briand, G. Guichard, 2006 .

SUBPOL: a novel SUcrose-Based Polymer support for solid-phase peptide synthesis and affinity chromatography applications.

T. Rohr, A. Bianco, J. Briand, 2003, Journal of the American Chemical Society.

A retro-inverso peptide corresponding to the GH loop of foot-and-mouth disease virus elicits high levels of long-lasting protective neutralizing antibodies.

F. Brown, S. Muller, J. Briand, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex

Daniel N. Wilson, M. Graf, C. Innis, 2015, Nature Structural &Molecular Biology.

Efficient synthesis of phthaloyl derivatives of α-amino carboxamides

J. Briand, G. Guichard, J. Casimir, 2001, Letters in Peptide Science.

Methyl 2-((succinimidooxy)carbonyl)benzoate (MSB): a new, efficient reagent for N-phthaloylation of amino acid and peptide derivatives.

J. Briand, G. Guichard, J. Casimir, 2002, The Journal of organic chemistry.

Antibacterial activity of a dual peptide targeting the Escherichia coli sliding clamp and the ribosome

J. Wagner, G. Guichard, J. Reichhart, 2020, RSC chemical biology.

Structure-based design of short peptide ligands binding onto the E. coli processivity ring.

J. Wagner, P. Dumas, V. Olieric, 2011, Journal of Medicinal Chemistry.

Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity.

H. Gronemeyer, J. Beyrath, S. Fournel, 2010, Cancer research.

Solid-phase synthesis of CD40L mimetics.

A. Bianco, S. Fournel, Sébastien Wieckowski, 2006, Organic & biomolecular chemistry.

Suppression of Tumor Growth and Angiogenesis by a Specific Antagonist of the Cell-Surface Expressed Nucleolin

P. Albanese, J. Briand, G. Guichard, 2008, PloS one.

Exploration of Requirements for Peptidomimetic Immune Recognition

J. Briand, G. Guichard, S. Muller, 1996, The Journal of Biological Chemistry.

Structure of antibody-bound peptides and retro-inverso analogues. A transferred nuclear Overhauser effect spectroscopy and molecular dynamics approach.

S. Muller, J. Briand, G. Guichard, 2001, Biochemistry.

The Anti-HIV Pseudopeptide HB-19 Forms a Complex with the Cell-surface-expressed Nucleolin Independent of Heparan Sulfate Proteoglycans*

S. Nisole, J. Briand, G. Guichard, 1999, The Journal of Biological Chemistry.

The HB-19 pseudopeptide 5[Kpsi(CH2N)PR]-TASP inhibits attachment of T lymophocyte- and macrophage-tropic HIV to permissive cells.

E. Dam, S. Nisole, S. Muller, 2000, AIDS research and human retroviruses.

Solution Structure of a Retro-inverso Peptide Analogue Mimicking the Foot-and-Mouth Disease Virus Major Antigenic Site

J. Briand, G. Guichard, S. Muller, 1999, The Journal of Biological Chemistry.

Hetero-oligomerization between the TNF receptor superfamily members CD40, Fas and TRAILR2 modulate CD40 signalling

H. Eibel, L. Willen, P. Schneider, 2017, Cell Death & Disease.

Synthesis of a large peptide mimicking the DNA binding properties of the sex determining protein, SRY

F. Heitz, G. Guichard, F. Poulat, 1992, FEBS letters.

Small multivalent architectures mimicking homotrimers of the TNF superfamily member CD40L: delineating the relationship between structure and effector function.

S. Fournel, Sébastien Wieckowski, O. Chaloin, 2007, Journal of the American Chemical Society.

Interaction of a Model Peptide on Gram Negative and Gram Positive Bacterial Sliding Clamps.

B. Lorber, J. Wagner, P. Dumas, 2019, ACS infectious diseases.

Differential modes of peptide binding onto replicative sliding clamps from various bacterial origins.

B. Lorber, J. Wagner, V. Olieric, 2014, Journal of medicinal chemistry.

Delivery of siRNA by tailored cell-penetrating urea-based foldamers.

A. Kichler, C. Douat, Mégane Bornerie, 2021, Chemical communications.

Sequencing of Oligourea Foldamers by Tandem Mass Spectrometry

G. Guichard, J. Schmitter, K. Bathany, 2013, Journal of the American Society for Mass Spectrometry.

Folding and Self-Assembly of Aromatic and Aliphatic Urea Oligomers: Towards Connecting Structure and Function

G. Guichard, Lucile Fischer, 2010 .

Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity

R. Guérois, F. Ochsenbein, G. Pinna, 2021, Science Advances.

1H, 13C, 15N NMR resonance assignments and secondary structure determination of the extra-cellular domain from the human proapoptotic TRAIL-R2 death receptor 5 (DR5-ECD)

G. Guichard, A. Loquet, Cameron D. Mackereth, 2018, Biomolecular NMR Assignments.

Thioether Analogues of Disulfide‐Bridged Cyclic Peptides Targeting Death Receptor 5: Conformational Analysis, Dimerisation and Consequences for Receptor Activation

H. Gronemeyer, D. Altschuh, C. Smulski, 2015, Chembiochem : a European journal of chemical biology.

Cysteine-rich Domain 1 of CD40 Mediates Receptor Self-assembly*

D. Speiser, P. Schneider, C. Smulski, 2013, The Journal of Biological Chemistry.

Cross-reactivity of Antibodies to Retro-Inverso Peptidomimetics with the Parent Protein Histone H3 and Chromatin Core Particle

J. Briand, G. Guichard, S. Muller, 1995, The Journal of Biological Chemistry.

Synthesis and structural characterization of alkyne-functionalized N-heterocyclic carbene complexes of ruthenium, palladium and rhodium

G. Guichard, G. Dahm, S. Bellemin‐Laponnaz, 2017 .

Multimerization of an apoptogenic TRAIL-mimicking peptide by using adamantane-based dendrons.

C. Smulski, A. Bianco, S. Fournel, 2013, Chemistry.

Characterization of the DNA and Membrane Interactions of a Bioreducible Cell Penetrating Foldamer in Its Monomeric and Dimeric Form.

A. Kichler, C. Douat, G. Guichard, 2020, The journal of physical chemistry. B.

Derivatization of Preformed Platinum N‑Heterocyclic Carbene Complexes with Amino Acid and Peptide Ligands and Cytotoxic Activities toward Human Cancer Cells

G. Guichard, G. Dahm, S. Bellemin‐Laponnaz, 2012 .

Ligand dimerization programmed by hybridization to study multimeric ligand-receptor interactions.

J. Beyrath, S. Fournel, G. Guichard, 2010, Chemical communications.

Synthesis of arginine aldehydes for the preparation of pseudopeptides.

J. Briand, G. Guichard, M. Friede, 1993, Peptide research.

Enhanced immunogenicity and cross-reactivity of retro-inverso peptidomimetics of the major antigenic site of foot-and-mouth disease virus.

F. Brown, S. Muller, J. Briand, 1995, Peptide research.

Structural comparison between retro-inverso and parent peptides: molecular basis for the biological activity of a retro-inverso analogue of the immunodominant fragment of VP1 coat protein from foot-and-mouth disease virus.

F. Brown, J. Carver, F. Fogolari, 1997, Biopolymers.

In situ iodination and X-ray crystal structure of a foldamer helix bundle.

G. Guichard, G. Collie, Karolina Pułka-Ziach, 2016, Chemical communications.

Preparation of N-Fmoc-Protected β2- and β3-Amino Acids and Their Use as Building Blocks for the Solid-Phase Synthesis of β-Peptides.

D. Seebach, G. Guichard, Stefan Abele, 1998 .

Inhibition of HIV infection by pseudopeptides blocking viral envelope glycoprotein-mediated membrane fusion and cell death.

J. Blanco, S. Muller, E. Jacotot, 1996, Virology.

Retro-Inverso Peptidomimetics as New Immunological Probes

H. Dumortier, J. Briand, G. Guichard, 1995, The Journal of Biological Chemistry.

Evidence of secondary structure by high-resolution magic angle spinning NMR spectroscopy of a bioactive peptide bound to different solid supports.

J. Furrer, K. Elbayed, A. Bianco, 2001, Journal of the American Chemical Society.

Ureidopeptide GLP-1 analogues with prolonged activity in vivo via signal bias and altered receptor trafficking† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02079a

D. Rognan, G. Guichard, B. Jones, 2019, Chemical science.

G. Guichard, G. Collie, Karolina Pułka-Ziach, 2016, Chemical science.

Nature-inspired synthetic oligourea foldamer channels allow water transport with high salt rejection

Sung Hyun Yoo, R. Kini, G. Guichard, 2023, Chem.

Microwave-enhanced solid-phase synthesis of N,N'-linked aliphatic oligoureas and related hybrids.

G. Guichard, Céline Douat-Casassus, P. Claudon, 2012, Organic letters.

Galactosylated 5-Hydroxylysine Mimetics for Glycopeptide Synthesis

J. Briand, G. Guichard, Aude Violette, 2004 .

Interaction of a Model Peptide on Gram Negative and Gram Positive Bacterial Sliding Clamps.

B. Lorber, J. Wagner, P. Dumas, 2019, ACS infectious diseases.