A. Barb

发表

High Yield Expression of Recombinant Human Proteins with the Transient Transfection of HEK293 Cells in Suspension.

Heather A. Moniz, K. Moremen, G. Subedi, 2015, Journal of visualized experiments : JoVE.

Mechanism and inhibition of LpxC: an essential zinc-dependent deacetylase of bacterial lipid A synthesis.

Pei Zhou, A. Barb, P. Zhou, 2008, Current pharmaceutical biotechnology.

Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.

Pei Zhou, Sang Hoon Joo, E. Toone, 2011, Chemistry & biology.

The immunoglobulin G1 N-glycan composition affects binding to each low affinity Fc γ receptor

G. Subedi, A. Barb, Ganesh P Subedi, 2016, mAbs.

A perspective on the structure and receptor binding properties of immunoglobulin G Fc.

Quinlin M Hanson, A. Barb, Q. Hanson, 2015, Biochemistry.

Expression and Display of Glycoengineered Antibodies and Antibody Fragments with an Engineered Yeast Strain

A. Barb, Anjali Shenoy, Srisaimaneesh Yalamanchili, 2021, Antibodies.

Fc γ receptor compositional heterogeneity: Considerations for immunotherapy development

A. Barb, 2020, The Journal of biological chemistry.

Multiple Variables at the Leukocyte Cell Surface Impact Fc γ Receptor-Dependent Mechanisms

A. Barb, K. Patel, J. T. Roberts, 2019, Front. Immunol..

Primary Human Natural Killer Cells Retain Proinflammatory IgG1 at the Cell Surface and Express CD16a Glycoforms with Donor-dependent Variability*

A. Barb, K. Patel, Joel D Nott, 2019, Molecular & Cellular Proteomics.

A single amino acid distorts the Fc γ receptor IIIb/CD16b structure upon binding immunoglobulin G1 and reduces affinity relative to CD16a

A. Barb, J. T. Roberts, Jacob T. Roberts, 2018, The Journal of Biological Chemistry.

CD16a with oligomannose-type N-glycans is the only “low-affinity” Fc γ receptor that binds the IgG crystallizable fragment with high affinity in vitro

G. Subedi, A. Barb, 2018, The Journal of Biological Chemistry.

Antibody Fucosylation Lowers the FcγRIIIa/CD16a Affinity by Limiting the Conformations Sampled by the N162-Glycan.

G. Subedi, A. Barb, A. M. Marcella, 2018, ACS chemical biology.

Role of the hinge and C-gamma-2/C-gamma-3 interface in immunoglobin G1 Fc domain motions: implications for Fc engineering

J. Prestegard, W. Lanzilotta, R. Walker, 2014 .

Continuous interdomain orientation distributions reveal components of binding thermodynamics

B. Donald, A. Yan, T. Oas, 2017, bioRxiv.

Three‐dimensional structure of the weakly associated protein homodimer SeR13 using RDCs and paramagnetic surface mapping

G. Montelione, J. Prestegard, Xu Wang, 2010, Protein science : a publication of the Protein Society.

Site-specific N-glycan Analysis of Antibody-binding Fc γ Receptors from Primary Human Monocytes*

A. Barb, K. Patel, J. T. Roberts, 2019, Molecular & Cellular Proteomics.

Restricted processing of CD 16 a / Fc g receptor IIIa N-glycans from primary human NK cells impacts structure and function

G. Subedi, A. Barb, K. Patel, 2018 .

Restricted processing of CD16a/Fc γ receptor IIIa N-glycans from primary human NK cells impacts structure and function

G. Subedi, A. Barb, K. Patel, 2018, The Journal of Biological Chemistry.

Uridine-based inhibitors as new leads for antibiotics targeting Escherichia coli LpxC.

C. Bertozzi, M. Hangauer, C. Raetz, 2009, Biochemistry.

From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses

M. Pazgier, W. Tolbert, N. Gohain, 2019, mAbs.

Kinetics of Neuraminidase Action on Glycoproteins by 1D and 2D NMR.

J. Prestegard, A. Barb, J. Glushka, 2011, Journal of chemical education.

The antibody-binding Fc gamma receptor IIIa / CD16a is N-glycosylated with high occupancy at all five sites

A. Barb, I. Amster, Elizabeth A. Lampros, 2022, Current research in immunology.

The Preparation and Solution NMR Spectroscopy of Human Glycoproteins Is Accessible and Rewarding.

G. Subedi, A. Barb, D. Falconer, 2019, Methods in enzymology.

Carbohydrate-Polypeptide Contacts in the Antibody Receptor CD16A Identified through Solution NMR Spectroscopy.

G. Subedi, A. Barb, D. Falconer, 2017, Biochemistry.

The Structural Role of Antibody N-Glycosylation in Receptor Interactions.

G. Subedi, A. Barb, Ganesh P Subedi, 2015, Structure.

Molecular Validation of LpxC as an Antibacterial Drug Target in Pseudomonas aeruginosa

M. Pirrung, C. Raetz, A. Erwin, 2006, Antimicrobial Agents and Chemotherapy.

Acyl-coenzyme A:(holo-acyl carrier protein) transacylase enzymes as templates for engineering

A. Barb, A. Marcella, 2018, Applied Microbiology and Biotechnology.

Probing alanine transaminase catalysis with hyperpolarized 13CD3-pyruvate.

J. Prestegard, A. Barb, J. Glushka, 2013, Journal of magnetic resonance.

Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques

M. Pazgier, W. Tolbert, N. Gohain, 2022, Frontiers in Immunology.

Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG3

M. Pazgier, W. Tolbert, N. Gohain, 2019 .

Allotype-specific processing of the CD16a N45-glycan from primary human natural killer cells and monocytes.

A. Barb, K. Patel, Jacob T. Roberts, 2020, Glycobiology.

Exchange facilitated indirect detection of hyperpolarized 15ND2-amido-glutamine.

J. Prestegard, A. Barb, J. Glushka, 2011, Journal of magnetic resonance.

Direct Characterization of the Maize Starch Synthase IIa Product Shows Maltodextrin Elongation Occurs at the Non-reducing End*

A. Myers, A. Barb, D. Falconer, 2016, The Journal of Biological Chemistry.

Acyl-coenzyme A:(holo-acyl carrier protein) transacylase enzymes as templates for engineering

A. Barb, A. Marcella, 2018, Applied Microbiology and Biotechnology.

Metabolic15N labeling of the N-glycosylated immunoglobulin G1 Fc with an engineered Saccharomyces cerevisiae strain

A. Barb, I. Amster, Anjali Shenoy, 2022, Journal of Biomolecular NMR.

Continuous interdomain orientation distributions reveal components of binding thermodynamics

Anthony K. Yan, Bruce Randall Donald, Terrence G. Oas, 2017, bioRxiv.

A synopsis of recent developments defining how N-glycosylation impacts immunoglobulin G structure and function.

Y. Yamaguchi, A. Barb, 2019, Glycobiology.

Kinetics of Neuraminidase Action on Glycoproteins by One- and Two-Dimensional NMR.

J. Prestegard, A. Barb, J. Glushka, 2011 .

The R117A variant of the Escherichia coli transacylase FabD synthesizes novel acyl-(acyl carrier proteins)

A. Barb, A. Marcella, 2017, Applied Microbiology and Biotechnology.

Intramolecular N-Glycan/Polypeptide Interactions Observed at Multiple N-Glycan Remodeling Steps through [13C,15N]-N-Acetylglucosamine Labeling of Immunoglobulin G1

A. Barb, 2014, Biochemistry.

NMR Analysis Demonstrates Immunoglobulin G N-glycans are Accessible and Dynamic

J. Prestegard, A. Barb, 2011, Nature chemical biology.

An encodable lanthanide binding tag with reduced size and flexibility for measuring residual dipolar couplings and pseudocontact shifts in large proteins

G. Subedi, A. Barb, 2016, Journal of biomolecular NMR.

An encodable lanthanide binding tag with reduced size and flexibility for measuring residual dipolar couplings and pseudocontact shifts in large proteins

G. Subedi, A. Barb, 2016, Journal of Biomolecular NMR.

The Structural Role of Ant ibody N-Glycosylation in Receptor Interactions Graphical Abstract Highlights

G. Subedi, A. Barb, 2015 .

NMR characterization of immunoglobulin G Fc glycan motion on enzymatic sialylation.

J. Prestegard, K. Moremen, Roy W. Johnson, 2012, Biochemistry.

C-terminal domain phosphatase-like family members (AtCPLs) differentially regulate Arabidopsis thaliana abiotic stress signaling, growth, and development

Jianhua Zhu, S. Yokoi, P. Hasegawa, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Recent Advances Toward Engineering Glycoproteins Using Modified Yeast Display Platforms.

A. Barb, Anjali Shenoy, 2022, Methods in molecular biology.

Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding

Pei Zhou, Ling Jiang, Christian R. H. Raetz, 2007, Proceedings of the National Academy of Sciences.

Inhibition of lipid A biosynthesis as the primary mechanism of CHIR-090 antibiotic activity in Escherichia coli.

Pei Zhou, C. Raetz, A. Barb, 2007, Biochemistry.

Structures of domains I and IV from YbbR are representative of a widely distributed protein family

G. Montelione, J. Prestegard, T. Acton, 2011, Protein science : a publication of the Protein Society.

A Nicotiana tabacum cell culture selected for accelerated growth on mannose has increased expression of phosphomannose isomerase

D. M. Pharr, A. Barb, J. Williamson, 2003 .

Phosphomannose isomerase in Nicotiana tabacum L. NT1 and Apium graveolens var. dulce L. cell suspension cultures.

A. Barb, 2002 .

Production of soluble pMHC-I molecules in mammalian cells using the molecular chaperone TAPBPR.

N. Sgourakis, A. Barb, G. I. Morozov, 2019, Protein engineering, design & selection : PEDS.

Fc γ receptor IIIa/CD16a processing correlates with the expression of glycan-related genes in human natural killer cells

A. Barb, E. Mace, W. Lorenz, 2020, The Journal of biological chemistry.

The weaker-binding Fc γ receptor IIIa F158 allotype retains sensitivity to N-glycan composition and exhibits a destabilized antibody-binding interface

A. Barb, Paul G. Kremer, 2022, The Journal of biological chemistry.

Intramolecular glycan-protein interactions in glycoproteins.

A. Borgert, A. Barb, D. Live, 2010, Methods in enzymology.

NMR detection and characterization of sialylated glycoproteins and cell surface polysaccharides

J. Prestegard, A. Barb, D. Freedberg, 2011, Journal of biomolecular NMR.

Structure, High Affinity, and Negative Cooperativity of the Escherichia coli Holo-(Acyl Carrier Protein):Holo-(Acyl Carrier Protein) Synthase Complex.

Sannie J. Culbertson, A. Barb, M. Shogren-Knaak, 2017, Journal of molecular biology.

Preparation of holo- and malonyl-[acyl-carrier-protein] in a manner suitable for analog development.

A. Barb, Fuyuan Jing, A. Marcella, 2015, Protein expression and purification.

Intradomain Interactions in an NMDA Receptor Fragment Mediate N-Glycan Processing and Conformational Sampling.

Anton V Sinitskiy, V. Pande, G. Subedi, 2019, Structure.

Lanthanide binding and IgG affinity construct: Potential applications in solution NMR, MRI, and luminescence microscopy

J. Prestegard, A. Barb, T. G. Ho, 2012, Protein science : a publication of the Protein Society.

Restricted motion of the conserved immunoglobulin G1 N-glycan is essential for efficient FcγRIIIa binding.

G. Subedi, A. Barb, Quinlin M. Hanson, 2014, Structure.

Site-specific N-glycan Analysis of Antibody-binding Fc γ Receptors from Primary Human Monocytes.

A. Barb, K. Patel, Jacob T. Roberts, 2020, Molecular & Cellular Proteomics.

Inhibiting N-glycan processing increases the antibody binding affinity and effector function of human natural killer cells.

G. Subedi, A. Barb, Paul G. Kremer, 2023, Immunology.

Direct Determination of the Site of Addition of Glucosyl Units to Maltooligosaccharide Acceptors Catalyzed by Maize Starch Synthase I

A. Myers, Ying Xie, A. Barb, 2018, Front. Plant Sci..

Mouse IgG2c Fc loop residues promote greater receptor-binding affinity than mouse IgG2b or human IgG1

A. Barb, D. Falconer, 2018, PloS one.

Branch-specific sialylation of IgG-Fc glycans by ST6Gal-I.

J. Prestegard, A. Barb, E. K. Brady, 2009, Biochemistry.

Immunoglobulin G1 Fc domain motions: implications for Fc engineering.

J. Prestegard, W. Lanzilotta, R. Walker, 2014, Journal of molecular biology.

Refolded recombinant Siglec5 for NMR investigation of complex carbohydrate binding.

J. Prestegard, Xu Wang, A. Barb, 2013, Protein expression and purification.