P. Vierling

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Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery

J. M. Benito, C. O. Mellet, Alejandro Méndez‐Ardoy, 2015 .

Polycationic amphiphilic cyclodextrins as gene vectors: effect of the macrocyclic ring size on the DNA complexing and delivery properties.

J. L. Jiménez Blanco, C. Di Giorgio, C. Ortiz Mellet, 2012, Organic & biomolecular chemistry.

β-Cyclodextrin-based polycationic amphiphilic "click" clusters: effect of structural modifications in their DNA complexing and delivery properties.

F. Santoyo-González, C. Di Giorgio, C. Ortiz Mellet, 2011, The Journal of organic chemistry.

Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery.

J. M. Benito, C. Di Giorgio, C. O. Mellet, 2011, Biomaterials.

Polycationic amphiphilic cyclodextrins for gene delivery: synthesis and effect of structural modifications on plasmid DNA complex stability, cytotoxicity, and gene expression.

Nicolas Guilloteau, Alejandro Díaz-Moscoso, J. M. Benito, 2009, Chemistry.

New perfluorinated polycationic dimerizable detergents for the formulation of monomolecular DNA nanoparticles and their in vitro transfection efficiency.

C. Di Giorgio, P. Vierling, K. Fabio, 2005, Biochimica et biophysica acta.

Transfection with fluorinated lipoplexes based on fluorinated analogues of DOTMA, DMRIE and DPPES.

P. Vierling, J. Gaucheron, C. Santaella, 2002, Biochimica et biophysica acta.

Gene transfer with a series of lipophilic DNA-binding molecules.

C. Sirlin, J. Behr, J. Rémy, 1994, Bioconjugate chemistry.

Convenient supported recyclable material based on dihydrolipoyl-residue for the reduction of disulfide derivatives

C. D. Giorgio, P. Vierling, C. Bienvenu, 2010 .

Novel amphiphilic cyclodextrin derivatives, their use in the pharmaceutical, cosmetic, food sectors and their application to the production of new nanosystems

J. M. Benito, P. Vierling, J. Defaye, 2006 .

Molecular Receptors. Structural Effects and Substrate Recognition in Binding of Organic and Biogenic Ammonium Ions by Chiral Polyfunctional Macrocyclic Polyethers Bearing Amino‐Acid and Other Side‐Chains

J. Behr, J. Lehn, P. Vierling, 1982 .

The [18]-N3O3 aza-oxa macrocycle: a selective receptor unit for primary ammonium cations

J. Lehn, P. Vierling, 1980 .

Multisite molecular receptors and co-systems ammonium cryptates of macrotricyclic structures

J. Lehn, P. Vierling, F. Kotzyba-Hibert, 1980 .

Stable ammonium cryptates of chiral macrocyclic receptor molecules bearing amino-acid side-chains

J. Behr, J. Lehn, P. Vierling, 1976 .

Fluorinated phosphatidylcholine-based liposomes: H+/Na+ permeability, active doxorubicin encapsulation and stability, in human serum.

P. Vierling, C. Santaella, F. Frézard, 1994, Biochimica et biophysica acta.

Phase behavior of fluorocarbon di-O-alkyl-glycerophosphocholines and glycerophosphoethanolamines and long-term shelf stability of fluorinated liposomes.

P. Vierling, C. Santaella, A. Gulik, 1997, Biochimica et biophysica acta.

Structure and interactive properties of highly fluorinated phospholipid bilayers.

T. McIntosh, S. Simon, P. Vierling, 1996, Biophysical journal.

Incorporation of new amphiphilic perfluoroalkylated bipyridine platinum and palladium complexes into liposomes: stability and structure-incorporation relationships.

P. Vierling, N. Garelli, 1992, Biochimica et biophysica acta.

Investigation of oral bioavailability and brain distribution of the Ind(8)‐Val conjugate of indinavir in rodents

W. Couet, P. Vierling, J. Greiner, 2005, The Journal of pharmacy and pharmacology.

Enhanced in vitro and in vivo cationic lipid‐mediated gene delivery with a fluorinated glycerophosphoethanolamine helper lipid

O. Boussif, P. Vierling, H. Kolbe, 2001, The journal of gene medicine.

Synthesis and anti-HIV activity of glucose-containing prodrugs derived from saquinavir, indinavir and nelfinavir.

P. Vierling, J. Greiner, A. Aubertin, 2001, Carbohydrate research.

Cell uptake mechanisms of glycosylated cationic pDNA–cyclodextrin nanoparticles

C. O. Mellet, A. Díaz‐Moscoso, C. D. Giorgio, 2015 .

Tailoring beta-cyclodextrin for DNA complexation and delivery by homogeneous functionalization at the secondary face.

C. Di Giorgio, J. G. García Fernández, C. O. Mellet, 2008, Organic letters.

Synthesis of new amphiphilic perfluoroalkylated bipyridines

P. Vierling, N. Garelli, 1992 .

Polycationic telomers and cotelomers for gene transfer: synthesis and evaluation of their an vitro transfection efficiency.

O. Boussif, P. Vierling, C. Santaella, 2002, Bioconjugate chemistry.

Formulation of Highly Functionalizable DNA Nanoparticles Based on 1,2‐Dithiolane Derivatives

C. Di Giorgio, P. Vierling, J. Greiner, 2015, Chembiochem : a European journal of chemical biology.

A short and efficient synthesis of 2′-deoxybenzo- and pyridoimidazole C-nucleosides

P. Vierling, R. Benhida, D. Guianvarc’h, 2003 .

Cationic Polysaccharides for Gene Delivery

A. Domb, A. Domb, P. Vierling, 2002 .

In vitro cationic lipid-mediated gene delivery with fluorinated glycerophosphoethanolamine helper lipids.

N. Sbirrazzuoli, O. Boussif, P. Vierling, 2001, Bioconjugate chemistry.

Highly fluorinated lipospermines for gene transfer: synthesis and evaluation of their in vitro transfection efficiency.

P. Vierling, J. Gaucheron, C. Santaella, 2001, Bioconjugate chemistry.

Formulation of PEG–folic acid coated nanometric DNA particles from perfluoroalkylated cationic dimerizable detergents and in vitro folate-targeted intracellular delivery

C. D. Giorgio, P. Vierling, J. Greiner, 2008 .

Polymorphic phase behavior of perfluoroalkylated phosphatidylcholines.

P. Vierling, C. Santaella, A. Gulik, 1994, Biochimica et biophysica acta.

Lipopolycationic telomers for gene transfer: synthesis and evaluation of their in vitro transfection efficiency.

O. Boussif, P. Vierling, H. Kolbe, 2000, Journal of medicinal chemistry.

Extended in vivo blood circulation time of fluorinated liposomes

P. Vierling, C. Santaella, F. Frézard, 1993, FEBS letters.

Synthesis and evaluation of the in vivo tolerance of amido fiuorocarbon/fluorocarbon and fluorocarbon/hydrocarbon double-chain phosphocholines deriving from diaminopropanols and serine

P. Vierling, C. Santaella, L. Clary, 1995 .

Membrane permeability and stability of liposomes made from highly fluorinated double-chain phosphocholines derived from diaminopropanol, serine or ethanolamine.

P. Vierling, C. Santaella, G. Verderone, 1997, Biochimica et biophysica acta.

Membrane permeability and stability in buffer and in human serum of fluorinated di-O-alkylglycerophosphocholine-based liposomes.

P. Vierling, C. Santaella, V. Ravily, 1996, Biochimica et biophysica acta.

Permeability and stability in buffer and in human serum of fluorinated phospholipid-based liposomes.

P. Vierling, C. Santaella, F. Frézard, 1994, Biochimica et biophysica acta.

Synthesis of new fluoroquinolones and evaluation of their in vitro activity on Toxoplasma gondii and Plasmodium spp.

R. Gozalbes, F. Derouin, P. Vierling, 2004, Bioorganic & medicinal chemistry letters.

An efficient mixed solid–liquid phase synthesis of a heterobifunctional amphiphilic PEG–NH2 derivative and its conjugation to folic acid

C. D. Giorgio, P. Vierling, J. Greiner, 2008 .

Polymorphic phase behavior of fluorocarbon double-chain phosphocholines derived from diaminopropanol, serine and ethanolamine and long-term shelf stability of their liposomes

P. Vierling, C. Santaella, P. Chang, 1997 .

Synthesis of acridine-nuclear localization signal (NLS) conjugates and evaluation of their impact on lipoplex and polyplex-based transfection.

C. Di Giorgio, P. Vierling, C. Boulanger, 2005, European journal of medicinal chemistry.

Improved in vitro gene transfer mediated by fluorinated lipoplexes in the presence of a bile salt surfactant

P. Vierling, J. Gaucheron, C. Santaella, 2001, The journal of gene medicine.

Synthesis of Highly Fluorinated Di-O-alk(en)yl-glycerophospholipids and Evaluation of Their Biological Tolerance

P. Vierling, C. Santaella, V. Ravily, 1996 .

New Perfluoroalkylated Phospholipids as Injectable Surfactants: Synthesis, Preliminary Physicochemical, and Biocompatibility Data.

P. Vierling, C. Santaella, J. Riess, 1992 .

A stereo- and regio-controlled synthesis of bromothiophenyl C-nucleosides. Tandem bromination-ribosylation via halogen dance process

P. Vierling, R. Benhida, D. Dubreuil, 2008 .

Design, synthesis and activity against Toxoplasma gondii, Plasmodium spp., and Mycobacterium tuberculosis of new 6-fluoroquinolones.

R. Gozalbes, F. Derouin, P. Vierling, 2006, European journal of medicinal chemistry.

Synthesis of mono- and di-substituted 2,4,5-trifluorobenzoic acid synthons, key precursors for biologically active 6-fluoroquinolones

P. Vierling, J. Greiner, G. Anquetin, 2005 .

Synthesis and characterization of new perfluoroalkylated side-chain ferrocenes and ferricinium salts

P. Vierling, C. Guillon, 1996 .

Synthesis and characterization of amphiphilic platinum and palladium complexes linked to perfluoroalkylated side-chain disubstituted bipyridines

P. Vierling, N. Garelli, 1992 .

New molybdenum and iron phosphoranides. Mechanism and stereochemistry of the rearrangement and migration of a phosphorus-bound allylic group into an iron-bound vinylic group

P. Vierling, J. Riess, 1986 .

On the origin of primitive cells: from nutrient intake to elongation of encapsulated nucleotides.

Cornelia Meinert, Uwe J Meierhenrich, U. Meierhenrich, 2010, Angewandte Chemie.

New bicyclam-GalCer analogue conjugates: synthesis and in vitro anti-HIV activity.

P. Vierling, J. Greiner, A. Aubertin, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and in vitro biological evaluation of valine-containing prodrugs derived from clinically used HIV-protease inhibitors.

P. Vierling, J. Greiner, A. Aubertin, 2008, European journal of medicinal chemistry.

Highly fluorinated amphiphiles as drug and gene carrier and delivery systems

P. Vierling, C. Santaella, J. Greiner, 2001 .

Synthesis of single- and double-chain fluorocarbon and hydrocarbon galactosyl amphiphiles and their anti-HIV-1 activity.

A M Aubertin, J. Fantini, P. Vierling, 2000, Carbohydrate research.

Phase behavior of fluorocarbon and hydrocarbon double-chain hydroxylated and galactosylated amphiphiles and bolaamphiphiles. Long-term shelf-stability of their liposomes.

P. Vierling, C. Santaella, J. Greiner, 1999, Chemistry and physics of lipids.

Improved stability of highly fluorinated phospholipid-based vesicles in the presence of bile salts.

P. Vierling, C. Santaella, C. Gadras, 1999, Journal of controlled release : official journal of the Controlled Release Society.

Transmembrane pH-driven Na+ permeability of fluorinated phospholipid-based membranes.

P. Vierling, C. Santaella, V. Ravily, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Molecular order and mobility within membranes made from fluorocarbon/fluorocarbon and fluorocarbon/hydrocarbon double-chain ether and amide phospholipids

P. Vierling, G. Duportail, C. Santaella, 1997 .

MISCIBILITY OF BINARY MIXTURES OF HIGHLY FLUORINATED DOUBLE-CHAIN GLYCEROPHOSPHOCHOLINES AND 1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE (DPPC)

P. Vierling, C. Santaella, J. Rolland, 1997 .

synthesis of single- and double-chain fluorocarbon and hydrocarbon β-linked galactose amphiphiles derived from serine

P. Vierling, C. Santaella, J. Greiner, 1995 .

Highly Stable Liposomes Derived from Perfluoroalkylated Glycerophosphocholines

P. Vierling, C. Santaella, J. Riess, 1991 .

Cytotoxic activity of new amphiphilic perfluoroalkylated bipyridine platinum and palladium complexes incorporated into liposomes

P. Vierling, G. Milano, N. Garelli, 1993 .

Synthesis and Anti-HIV Activity of Prodrugs Derived from Saquinavir and Indinavir

P. Vierling, J. Greiner, A. Aubertin, 2000, Antiviral chemistry & chemotherapy.

Synthesis and Studies of Modified Oligonucleotides- Directed Triple Helix Formation at the Purine-Pyrimidine Interrupted Site

P. Vierling, R. Benhida, D. Guianvarc’h, 2003, Nucleosides, nucleotides & nucleic acids.

Amphiphilic anionic analogues of galactosylceramide: synthesis, anti-HIV-1 activity, and gp120 binding.

J. Fantini, P. Vierling, J. Greiner, 2001, Journal of medicinal chemistry.

Prodrugs of HIV protease inhibitors-saquinavir, indinavir and nelfinavir-derived from diglycerides or amino acids: synthesis, stability and anti-HIV activity.

P. Vierling, J. Greiner, A. Aubertin, 2004, Organic & biomolecular chemistry.

AMD3100 conjugates as components of targeted nonviral gene delivery systems: synthesis and in vitro transfection efficiency of CXCR4-expressing cells.

A. Domb, C. Di Giorgio, P. Vierling, 2004, Bioconjugate chemistry.

Prodrugs of HIV protease inhibitors.

P. Vierling, J. Greiner, 2003, Current pharmaceutical design.

Necrosis of HepG2 cancer cells induced by the vibration of magnetic particles

G. Bossis, Biran Wang, C. D. Giorgio, 2013 .

Blood substitutes. Preparation, physiology and medical applications. Edited by K. C. Lowe, VCH Verlagsgesellschaft, Weinheim, 1988. 187 pp., bound, DM 168.—ISBN 3‐527‐ 26556‐2

P. Vierling, 1989 .

Membranes, Vesicles, and Other Supramolecular Systems Made from Fluorinated Amphiphiles

P. Vierling, C. Santaella, L. Zarif, 2018 .

PERFLUOROALKYLATED PHOSPHOCHOLINES, IMPROVED SYNTHESIS, SURFACE ACTIVITY, FLUOROCARBON EMULSIFYING CAPABILITY AND BIOLOGICAL PROPERTIES

P. Vierling, S. Gaentzler, 1993 .

Amphiphilic oligoethyleneimine-β-cyclodextrin "click" clusters for enhanced DNA delivery.

J. L. Jiménez Blanco, C. Di Giorgio, J. G. García Fernández, 2013, The Journal of organic chemistry.

Cyclodextrin-scaffolded amphiphilic aminoglucoside clusters: self-assembling and gene delivery capabilities

J. M. Benito, C. D. Giorgio, P. Vierling, 2014 .

Rational design of cationic cyclooligosaccharides as efficient gene delivery systems.

Alejandro Díaz-Moscoso, A. Mazzaglia, N. Micali, 2008, Chemical communications.

Novel galactosylated polyamine bolaamphiphiles for gene delivery.

C. Di Giorgio, P. Vierling, K. Fabio, 2003, Bioconjugate chemistry.

In vitro gene transfer with a novel galactosylated spermine bolaamphiphile.

P. Vierling, J. Gaucheron, C. Santaella, 2001, Bioconjugate chemistry.

Stable and selective guanidinium and imidazolium complexes of a macrocyclic receptor molecule

R. Hayward, J. Lehn, P. Vierling, 1979 .

Efficient solid-phase synthesis of perfluoroalkylated dimerizable cationic detergents for gene delivery

C. D. Giorgio, P. Vierling, N. Guilloteau, 2009 .

Synthesis and preliminary data on the biocompatibility and emulsifying properties of perfluoroalkylated phosphoramidates as injectable surfactants

P. Vierling, J. Riess, M. Krafft, 1991 .

Perfluoroalkylated surfactants: relationships between structure and acute toxicity in mice.

P. Vierling, L. Zarif, J. Greiner, 1992, Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology.

Transepithelial Transport of Prodrugs of the HIV Protease Inhibitors Saquinavir, Indinavir, and Nelfinavir Across Caco-2 Cell Monolayers

P. Vierling, J. Greiner, B. Gaucher, 2002, Pharmaceutical Research.

In Vivo Characterization of Dynein-Driven nanovectors Using Drosophila Oocytes

S. Fiorucci, C. Di Giorgio, P. Vierling, 2013, PloS one.

Fluorinated phospholipid-based vesicles as potential drug carriers: encapsulation/sustaining of drugs and stability in human serum.

P. Vierling, C. Santaella, F. Frézard, 1994, Artificial cells, blood substitutes, and immobilization biotechnology.

A general approach for the microrheology of cancer cells by atomic force microscopy.

G. Bossis, Biran Wang, C. Di Giorgio, 2013, Micron.

Quinolone-based drugs against Toxoplasma gondii and Plasmodium spp.

P. Vierling, J. Greiner, G. Anquetin, 2005, Current Drug Targets - Infectious Disorders.

Relevance of the acid-base phosphorane/phosphoranide equilibrium to the tautomeric phosphorane/phosphine equilibrium in the action of an activated ketone on tetracyclic tetraaminophosphoranes

P. Vierling, F. Bouvier, J. Dupart, 1988 .

Molecular packing of highly fluorinated phosphatidylcholines in monolayers.

P. Vierling, C. Santaella, J. Rolland, 1996, Chemistry and physics of lipids.

Mannosyl-coated nanocomplexes from amphiphilic cyclodextrins and pDNA for site-specific gene delivery.

J. M. Benito, C. Di Giorgio, Alejandro Méndez‐Ardoy, 2011, Biomaterials.

The Origin of Primitive Cells, Nutrient Intake, and Non-Enzymatic Elongation of Encapsulated Nucleotides

U. Meierhenrich, J. Dworkin, P. Vierling, 2009 .

MOLECULAR ORDER AND MOBILITY WITHIN LIPOSOMAL MEMBRANE MADE FROM HIGHLY FLUORINATED PHOSPHOLIPIDS

P. Vierling, C. Santaella, 1995 .