S. Fumoto

发表

Hepatic gene delivery system electrostatically assembled with glycyrrhizin.

H. Sasaki, T. Kurosaki, Hiroo Nakagawa, 2014, Molecular pharmaceutics.

Ternary complexes of pDNA, polyethylenimine, and gamma-polyglutamic acid for gene delivery systems.

H. Sasaki, T. Niidome, T. Kurosaki, 2009, Biomaterials.

Molecular weight-dependent gene transfection activity of unmodified and galactosylated polyethyleneimine on hepatoma cells and mouse liver.

S. Kawakami, M. Hashida, F. Yamashita, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Analysis of hepatic disposition of native and galactosylated polyethylenimine complexed with plasmid DNA in perfused rat liver.

S. Kawakami, M. Hashida, F. Yamashita, 2003, Drug metabolism and pharmacokinetics.

Chondroitin sulfate capsule system for efficient and secure gene delivery.

H. Sasaki, T. Kurosaki, Hiroo Nakagawa, 2010, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

Novel galactosylated liposomes for hepatocyte-selective targeting of lipophilic drugs.

S. Kawakami, M. Hashida, F. Yamashita, 2001, Journal of pharmaceutical sciences.

Multiple components in serum contribute to hepatic transgene expression by lipoplex in mice

H. Sasaki, S. Fumoto, K. Nishida, 2011, The journal of gene medicine.

Analysis of Hepatic Disposition of Galactosylated Cationic Liposome/Plasmid DNA Complexes in Perfused Rat Liver

S. Kawakami, M. Hashida, F. Yamashita, 2003, Pharmaceutical Research.

A pH-Adjustable Tissue Clearing Solution That Preserves Lipid Ultrastructures: Suitable Tissue Clearing Method for DDS Evaluation

S. Kawakami, T. Hirayama, H. Nagasawa, 2020, Pharmaceutics.

Effect of solution composition of plasmid DNA on gene transfection following liver surface administration in mice.

H. Sasaki, M. Nakashima, S. Fumoto, 2005, Biological & pharmaceutical bulletin.

Delivery advantage to the unilateral kidney by direct drug application to the kidney surface in rats and pharmacokinetic verification based on a physiological model

H. Sasaki, M. Nakashima, S. Fumoto, 2005, Journal of drug targeting.

Absorption and distribution characteristics of 5-fluorouracil (5-FU) after an application to the liver surface in rats in order to reduce systemic side effects.

H. Sasaki, Yukinobu Kodama, M. Nakashima, 2008, Biological & pharmaceutical bulletin.

Improved stomach selectivity of gene expression following microinstillation of plasmid DNA onto the gastric serosal surface in mice.

Hiroki Ishii, H. Sasaki, Yukinobu Kodama, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Highly stomach-selective gene transfer following gastric serosal surface instillation of naked plasmid DNA in rats

Hiroki Ishii, H. Sasaki, Yukinobu Kodama, 2008, Journal of Gastroenterology.

Evaluation of changes in hepatic disposition of phenolsulfonphthalein, indocyanine green and fluorescein isothiocyanate‐dextran at low temperatures using a rat liver perfusion system

H. Sasaki, S. Fumoto, K. Nishida, 2012, The Journal of pharmacy and pharmacology.

Pretreatment with epidermal growth factor enhances naked plasmid DNA transfer onto gastric serosal surface in mice.

S. Fumoto, K. Nishida, N. Yoshikawa, 2012, Biological & pharmaceutical bulletin.

Spleen-selective gene transfer following the administration of naked plasmid DNA onto the spleen surface in mice.

H. Sasaki, Yukinobu Kodama, M. Nakashima, 2007, Biological & pharmaceutical bulletin.

Unilateral lung-selective gene transfer following the administration of naked plasmid DNA onto the pulmonary pleural surface in mice.

H. Sasaki, Yukinobu Kodama, M. Nakashima, 2007, Biological & pharmaceutical bulletin.

Unilateral kidney-selective gene transfer following the administration of naked plasmid DNA to the kidney surface in mice.

H. Sasaki, M. Nakashima, S. Fumoto, 2005, Biological & pharmaceutical bulletin.

Monitoring method for transgene expression in target tissue by blood sampling

H. Sasaki, S. Fumoto, K. Nishida, 2019, Biotechnology reports.

Tissue suction-mediated gene transfer to the beating heart in mice

K. Shimizu, S. Kawakami, M. Hashida, 2020, PloS one.

In Vivo Gene Delivery to the Liver Using Novel Galactosylated Cationic Liposomes

S. Kawakami, M. Hashida, F. Yamashita, 2000, Pharmaceutical Research.

Stomach- and site-selective delivery of 5-fluorouracil following its application on the gastric serosal surface in rats.

H. Sasaki, M. Nakashima, S. Fumoto, 2005, Biological & pharmaceutical bulletin.

Suppression of Peritoneal Fibrosis by Sonoporation of Hepatocyte Growth Factor Gene-Encoding Plasmid DNA in Mice

S. Kawakami, Hidefumi Mukai, S. Fumoto, 2021, Pharmaceutics.

The Insertion Timing of PEGylated Lipids to Galactosylated Lipoplexes Is Important for Liver-Selective Transfection in Mice

S. Kawakami, M. Hashida, H. Sasaki, 2016 .

Effect of viscous additives on the absorption and hepatic disposition of 5‐fluorouracil (5‐FU) after application to liver surface in rats

H. Sasaki, Yukinobu Kodama, S. Fumoto, 2012, The Journal of pharmacy and pharmacology.

Effect of Chronic Kidney Disease on Hepatic Clearance of Drugs in Rats.

S. Fumoto, K. Nishida, Ayako Tokunaga, 2020, Biological & pharmaceutical bulletin.

Combination of nanoparticles with physical stimuli toward cancer therapy.

S. Kawakami, S. Fumoto, 2014, Biological & pharmaceutical bulletin.

Application of Direct Sonoporation from a Defined Surface Area of the Peritoneum: Evaluation of Transfection Characteristics in Mice

S. Kawakami, S. Fumoto, K. Nishida, 2019, Pharmaceutics.

Effect of the particle size of galactosylated lipoplex on hepatocyte-selective gene transfection after intraportal administration.

S. Kawakami, M. Hashida, F. Yamashita, 2006, Biological & pharmaceutical bulletin.

Splenic Delivery System of pDNA through Complexes Electrostatically Constructed with Protamine and Chondroitin Sulfate.

H. Sasaki, T. Kurosaki, Hiroo Nakagawa, 2018, Biological & pharmaceutical bulletin.

Change in pharmacokinetics of model compounds with different elimination processes in rats during hypothermia.

H. Sasaki, M. Nakashima, S. Fumoto, 2007, Biological & pharmaceutical bulletin.

Flavonoids Enhance Lipofection Efficiency and Ameliorate Cytotoxicity in Colon26 and HepG2 Cells via Oxidative Stress Regulation

S. Fumoto, K. Nishida, Hirotaka Miyamoto, 2022, Pharmaceutics.

Title Secure and effective gene delivery system of plasmid DNA coated bypolynucleotide

H. Sasaki, T. Kurosaki, Tadahiro Nakamura, 2017 .

Secure and effective gene delivery system of plasmid DNA coated by polynucleotide

H. Sasaki, T. Kurosaki, Tadahiro Nakamura, 2015, Journal of drug targeting.

Enhanced hepatocyte-selective in vivo gene expression by stabilized galactosylated liposome/plasmid DNA complex using sodium chloride for complex formation.

S. Kawakami, M. Hashida, F. Yamashita, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

Effect of renal ischaemia/reperfusion‐induced acute kidney injury on pharmacokinetics of midazolam in rats

S. Fumoto, K. Nishida, Ayako Tokunaga, 2019, The Journal of pharmacy and pharmacology.

Safety of liver surface instillation of plasmid DNA in normal and carbon tetrachloride-induced hepatitis mice.

S. Fumoto, K. Nishida, J. Nakamura, 2011, Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.

Evaluation of Enhanced Peritoneum Permeability in Methylglyoxal-treated Rats as a Diagnostic Method for Peritoneal Damage

H. Sasaki, Yukinobu Kodama, M. Nakashima, 2007, Pharmaceutical Research.

Understanding In Vivo Fate of Nucleic Acid and Gene Medicines for the Rational Design of Drugs

S. Fumoto, K. Nishida, Tsuyoshi Yamamoto, 2021, Pharmaceutics.

Targeted co-delivery of protein and drug to a tumor in vivo by sophisticated RGD-modified lipid-calcium carbonate nanoparticles.

S. Kawakami, S. Fumoto, K. Nishida, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Gene therapy for gastric diseases.

S. Fumoto, K. Nishida, J. Nakamura, 2008, Current gene therapy.

Effect of absorption enhancers on the absorption of FD-4 as a poorly absorbable marker macromolecule from the liver surface in rats

H. Sasaki, S. Fumoto, K. Nishida, 2014 .

Regional Delivery of Model Compounds and 5-Fluorouracil to the Liver by Their Application to the Liver Surface in Rats: Its Implication for Clinical Use

H. Sasaki, Yukinobu Kodama, M. Nakashima, 2005, Pharmaceutical Research.

Co-delivery Systems of Multiple Drugs Using Nanotechnology for Future Cancer Therapy.

S. Fumoto, K. Nishida, 2020, Chemical & pharmaceutical bulletin.

Effect of Metabolic Inhibitors on the Hepatic Disposition of 5-Fluorouracil after Application to the Rat Liver Surface.

S. Fumoto, K. Nishida, Hirotaka Miyamoto, 2016, Biological & pharmaceutical bulletin.

Rubbing gastric serosal surface enhances naked plasmid DNA transfer in rats and mice.

Hiroki Ishii, M. Nakashima, S. Fumoto, 2011, Biological & pharmaceutical bulletin.

Stomach-selective gene transfer following the administration of naked plasmid DNA onto the gastric serosal surface in mice.

H. Sasaki, Yukinobu Kodama, M. Nakashima, 2006, Biological & pharmaceutical bulletin.

Influence of Liver Intoxication by Carbon Tetrachloride or D-Galactosamine on Absorption of Fluorescein Isothiocyanate-Dextran-10 and Other Marker Compounds with Different Molecular Weights from the Rat Liver Surface.

S. Fumoto, K. Nishida, Ayako Tokunaga, 2020, Biological and Pharmaceutical Bulletin.

Ultrasound‐responsive nanobubble‐mediated gene transfection in the cerebroventricular region by intracerebroventricular administration in mice

S. Kawakami, Yuki Fuchigami, S. Fumoto, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Liver site-specific gene transfer following the administration of naked plasmid DNA to the liver surface in mice.

H. Sasaki, M. Nakashima, S. Fumoto, 2004, Biological & pharmaceutical bulletin.

Absorption characteristics of model compounds from the small intestinal serosal surface and a comparison with other organ surfaces

H. Sasaki, M. Nakashima, S. Fumoto, 2005, The Journal of pharmacy and pharmacology.

Three-Dimensional Imaging of the Intracellular Fate of Plasmid DNA and Transgene Expression: ZsGreen1 and Tissue Clearing Method CUBIC Are an Optimal Combination for Multicolor Deep Imaging in Murine Tissues

Shigeru Kawakami, S. Kawakami, S. Fumoto, 2016, PloS one.

Enhanced gene expression in lung by a stabilized lipoplex using sodium chloride for complex formation

S. Kawakami, M. Hashida, F. Yamashita, 2005, The journal of gene medicine.

Interaction of Lipoplex with Albumin Enhances Gene Expression in Hepatitis Mice

M. Nakashima, S. Fumoto, K. Nishida, 2020, Pharmaceutics.

Interaction with Blood Components Plays a Crucial Role in Asialoglycoprotein Receptor-Mediated in Vivo Gene Transfer by Galactosylated Lipoplex

S. Kawakami, M. Hashida, F. Yamashita, 2005, Journal of Pharmacology and Experimental Therapeutics.

Development of Effective Cancer Vaccine Using Targeting System of Antigen Protein to APCs

H. Sasaki, T. Kurosaki, Hiroo Nakagawa, 2011, Pharmaceutical Research.

Development of an apolipoprotein E mimetic peptide–lipid conjugate for efficient brain delivery of liposomes

Hidefumi Mukai, S. Fumoto, H. Arima, 2023, Drug delivery.

Efficient gene transfection to the brain with ultrasound irradiation in mice using stabilized bubble lipopolyplexes prepared by the surface charge regulation method

S. Kawakami, Yuki Fuchigami, S. Fumoto, 2018, International journal of nanomedicine.

Targeted Gene Delivery: Importance of Administration Routes

S. Kawakami, M. Hashida, S. Fumoto, 2013 .

PEGylated liposomes loading palmitoyl prednisolone for prolonged blood concentration of prednisolone.

S. Kawakami, H. Sasaki, Hiroo Nakagawa, 2006, Biological & pharmaceutical bulletin.

One-step formation of lipid-polyacrylic acid-calcium carbonate nanoparticles for co-delivery of doxorubicin and curcumin

S. Fumoto, K. Nishida, N. Kuroda, 2017, Journal of drug targeting.

Prolonged blood concentration of prednisolone after intravenous injection of liposomal palmitoyl prednisolone.

H. Sasaki, Tadahiro Nakamura, N. Ichikawa, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Targeted Delivery of Prostaglandin E1 to Hepatocytes Using Galactosylated Liposomes

S. Kawakami, M. Hashida, F. Yamashita, 2000, Journal of drug targeting.

Characterization of transgene expression and pDNA distribution of the suctioned kidney in mice

K. Shimizu, S. Kawakami, Yuki Fuchigami, 2017, Drug delivery.

Rac-mediated macropinocytosis is a critical route for naked plasmid DNA transfer in mice.

Hiroki Ishii, Xuan Wang, M. Nakashima, 2009, Molecular pharmaceutics.

The role of fibronectin in pulmonary gene transfer following intravenous administration of lipoplex in mice.

M. Nakashima, S. Fumoto, K. Nishida, 2013, Biological & pharmaceutical bulletin.

Efficient in vivo gene transfer by intraperitoneal injection of plasmid DNA and calcium carbonate microflowers in mice.

H. Sasaki, T. Kitahara, S. Fumoto, 2012, Molecular pharmaceutics.

Evaluation for effect of hypothermia on the disposition of 4‐nitrophenol in rats by in‐vitro metabolism study and rat liver perfusion system

M. Nakashima, S. Fumoto, K. Nishida, 2013, The Journal of pharmacy and pharmacology.

Determining Transgene Expression Characteristics Using a Suction Device with Multiple Hole Adjusting a Left Lateral Lobe of the Mouse Liver.

K. Shimizu, S. Kawakami, Yuki Fuchigami, 2018, Biological and Pharmaceutical Bulletin.

Effective intraperitoneal gene transfection system using nanobubbles and ultrasound irradiation

S. Kawakami, Yuki Fuchigami, S. Fumoto, 2017, Drug delivery.

Edaravone, a cytoprotective drug, enhances transgene expression mediated by lipoplexes in HepG2 cells and mice

Masakazu Tanaka, S. Fumoto, K. Nishida, 2018, International journal of pharmaceutics.

Evaluation of mRNA expression of drug-metabolizing enzymes in acetaminophen-induced hepatotoxicity using a three-dimensional hepatocyte culture system

S. Fumoto, K. Nishida, Takashi Tanaka, 2020, Xenobiotica; the fate of foreign compounds in biological systems.

Evaluation for Peritoneal Injury at an Early Stage Using Dual Macromolecular Markers.

M. Nakashima, S. Fumoto, K. Nishida, 2016, Biological and Pharmaceutical Bulletin.

Novel diagnostic method of peritoneal injury using dual macromolecular markers.

M. Nakashima, S. Fumoto, K. Nishida, 2014, Biological & pharmaceutical bulletin.

Evaluation of hypothermia on the in vitro metabolism and binding and in vivo disposition of midazolam in rats

H. Sasaki, M. Nakashima, S. Fumoto, 2015, Biopharmaceutics & drug disposition.

Rubbing gastric serosal surface enhances naked plasmid DNA transfer in rats and mice.

Hiroki Ishii, M. Nakashima, S. Fumoto, 2011, Biological and Pharmaceutical Bulletin.

Diffusion coefficient of cationic liposomes during lipoplex formation determines transfection efficiency in HepG2 cells.

S. Fumoto, K. Nishida, Die Hu, 2023, International journal of pharmaceutics.

One-Step Formation Method of Plasmid DNA-Loaded, Extracellular Vesicles-Mimicking Lipid Nanoparticles Based on Nucleic Acids Dilution-Induced Assembly

S. Fumoto, K. Nishida, Hirotaka Miyamoto, 2024, Cells.