J. Rademann

R. Haag, J. Rademann, E. Rühl, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Effect of prostaglandin E2 and 3-morpholinosydnonimine (SIN-1) on arachidonic acid metabolism in fMLP-stimulated rat neutrophils and on thrombin-induced human platelet aggregation

A. Dembińska-kieć, J. Rademann, T. Simmet, 1992, Agents and Actions.

Pharmacological inhibition of FSGS-related TRPC6 gain of function mutants by semisynthetic larixol-derived compounds

M. Schaefer, J. Rademann, Sebastian Köhling, 2017 .

Peptide–Heterocycle Chimera: New Classes of More Drug-Like Peptidomimetics by Ligations of Peptide–Bis(electrophiles) with Various Bis(nucleophiles)

Ahsanullah, J. Rademann, F. Ansari, 2011 .

Advanced polymer reagents based on activated reactants and reactive intermediates: powerful novel tools in diversity-oriented synthesis.

J. Rademann, 2003, Methods in enzymology.

Endotoxin-like properties of a rhamnolipid exotoxin from Burkholderia (Pseudomonas) plantarii: immune cell stimulation and biophysical characterization

Jörg Rademann, Holger Heine, M. Koch, 2006, Biological chemistry.

Alkylating Polymers: Resin-Released Carbenium Ions as Versatile Reactive Intermediates in Polymer-Assisted Solution-Phase Synthesis.

G. Jung, D. Schmid, J. Rademann, 2001, Angewandte Chemie.

One-Pot Synthesis of Unprotected Anomeric Glycosyl Thiols in Water for Glycan Ligation Reactions with Highly Functionalized Sugars.

N. Budisa, J. Rademann, J. Schiller, 2016, Angewandte Chemie.

Trimellitic anhydride linker (TAL)—highly orthogonal conversions of primary amines employed in the parallel synthesis of labeled carbohydrate derivatives ☆ ☆☆

J. Rademann, J. Bauer, 2003 .

New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.

Jörg Rademann, C. Pérez, J. Rademann, 2012, Journal of medicinal chemistry.

Flexible, polymer-supported synthesis of sphingosine derivatives provides ceramides with enhanced biological activity.

Samer I. Al-Gharabli, J. Rademann, Pradeep Kumar, 2014, Bioorganic & medicinal chemistry.

A NEW METHOD FOR THE SOLID PHASE SYNTHESIS OF OLIGOSACCHARIDES

J. Rademann, R. Schmidt, 1996 .

alpha-Ketocarbonyl peptides: a general approach to reactive resin-bound intermediates in the synthesis of peptide isosteres for protease inhibitor screening on solid support.

M. Meldal, J. Rademann, A. Papanikos, 2001, Journal of the American Chemical Society.

Tailoring ultraresins based on the cross-linking of polyethylene imines. Comparative investigation of the chemical composition, the swelling, the mobility, the chemical accessibility, and the performance in solid-phase synthesis of very high loaded resins.

J. Rademann, M. Barth, 2004, Journal of combinatorial chemistry.

High loading polymer reagents based on polycationic Ultraresins. Polymer-supported reductions and oxidations with increased efficiency

J. Rademann, M. Barth, S. A. Shah, 2004 .

Selective Inhibitors of the Protein Tyrosine Phosphatase SHP2 Block Cellular Motility and Growth of Cancer Cells in vitro and in vivo

W. Birchmeier, G. Wolber, U. Heinemann, 2015, ChemMedChem.

Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking

Jörg Rademann, Walter Birchmeier, Martin Würtele, 2008, Proceedings of the National Academy of Sciences.

Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.

J. Rademann, A. Schütz, M. Lisurek, 2012, Angewandte Chemie.

Oxidizing Polymers: A Polymer-Supported, Recyclable Hypervalent Iodine(V) Reagent for the Efficient Conversion of Alcohols, Carbonyl Compounds, and Unsaturated Carbamates in Solution J.R. gratefully acknowledges generous support from Prof. M. E. Maier, Tübingen, the Strukturfonds of the University o

G. Jung, J. Rademann, A. Mengel, 2001, Angewandte Chemie.

Protein‐Templated Fragment Ligations—From Molecular Recognition to Drug Discovery

J. Rademann, C. Arkona, Carolin Tauber, 2017, Angewandte Chemie.

The transcription factor STAT5 catalyzes Mannich ligation reactions yielding inhibitors of leukemic cell proliferation

J. Rademann, C. Arkona, M. Lisurek, 2019, Nature Communications.

Integrating Combinatorial Synthesis and Bioassays

Günther Jung, Jörg Rademann, G. Jung, 2000, Science.

Cyclative cleavage through dipolar cycloaddition: polymer-bound azidopeptidylphosphoranes deliver locked cis-triazolylcyclopeptides as privileged protein binders.

Jörg Rademann, Ahsanullah, J. Rademann, 2010, Angewandte Chemie.

Sensitized Detection of Inhibitory Fragments and Iterative Development of Non‐Peptidic Protease Inhibitors by Dynamic Ligation Screening†

Jörg Rademann, Rolf Hilgenfeld, R. Hilgenfeld, 2008, Angewandte Chemie.

C-acylations of polymeric phosphoranylidene acetates for C-terminal variation of peptide carboxylic acids.

J. Rademann, Adeeb El‐Dahshan, Steffen Weik, 2007, Organic letters.

A phosphorane as supported acylanion equivalent: linker reagents for smooth and versatile C-C coupling reactions.

J. Rademann, Steffen Weik, 2003, Angewandte Chemie.

Light-switched inhibitors of protein tyrosine phosphatase PTP1B based on phosphonocarbonyl phenylalanine as photoactive phosphotyrosine mimetic.

J. Rademann, A. Schütz, A. Schütz, 2015, Bioorganic & medicinal chemistry.

Catalytic activation of pre-substrates via dynamic fragment assembly on protein templates

J. Rademann, Edyta Burda, 2014, Nature Communications.

Dynamic Substrate Enhancement for the Identification of Specific, Second‐Site‐Binding Fragments Targeting a Set of Protein Tyrosine Phosphatases

J. Rademann, M. Groves, Marco F. Schmidt, 2011, Chembiochem : a European journal of chemical biology.

Dynamic template-assisted strategies in fragment-based drug discovery

Jörg Rademann, J. Rademann, Marco F Schmidt, 2009, Trends in Biotechnology.

Selective identification of cooperatively binding fragments in a high-throughput ligation assay enables development of a picomolar caspase-3 inhibitor.

J. Rademann, S. Keller, Marco F. Schmidt, 2009, Angewandte Chemie.

Chemoenzymatic synthesis of a glycolipid library and elucidation of the antigenic epitope for construction of a vaccine against Lyme disease.

R. Schumann, J. Rademann, B. Rupp, 2010, Chemistry.

Fmoc-based synthesis of peptide thioesters for native chemical ligation employing a tert-butyl thiol linker.

J. Rademann, R. Raz, 2011, Organic letters.

Spatially resolved single bead analysis: homogeneity, diffusion, and adsorption in cross-linked polystyrene.

R. Brock, H. Egelhaaf, J. Rademann, 2001, Chemistry.

Alzheimer’s Disease: Identification and Development of β‐Secretase (BACE‐1) Binding Fragments and Inhibitors by Dynamic Ligation Screening (DLS)

J. Rademann, M. I. Fernández-Bachiller, M. Lisurek, 2013, ChemMedChem.

An Efficient Method for the Synthesis of Peptide Aldehyde Libraries Employed in the Discovery of Reversible SARS Coronavirus Main Protease (SARS‐CoV Mpro) Inhibitors

Jörg Rademann, Gerhard Klebe, Rolf Hilgenfeld, 2006, Chembiochem : a European journal of chemical biology.

Hydrophobically assisted switching phase synthesis: the flexible combination of solid-phase and solution-phase reactions employed for oligosaccharide preparation.

J. Rademann, J. Bauer, 2005, Journal of the American Chemical Society.

Solid-Phase Supported Synthesis of the Branched Pentasaccharide Moiety That Occurs in Most Complex Type N-Glycan Chains.

J. Rademann, R. Schmidt, A. Geyer, 1998, Angewandte Chemie.

Repetitive Solid Phase Glycosylation on an Alkyl Thiol Polymer Leading to Sugar Oligomers Containing 1,2-trans- and 1,2-cis-Glycosidic Linkages†

J. Rademann, R. Schmidt, 1997 .

Multivalent presentation of the cell-penetrating peptide nona-arginine on a linear scaffold strongly increases its membrane-perturbing capacity.

R. Brock, M. Adjobo-Hermans, J. Rademann, 2014, Biochimica et biophysica acta.

Solid-phase synthesis of a glycosylated hexapeptide of human sialophorin, using the trichloroacetimidate method.

J. Rademann, R. Schmidt, 1995, Carbohydrate research.

Sulfation Pattern Dependent Iron(III) Mediated Interleukin‐8 Glycan Binding

J. Dürig, J. Rademann, S. Yitzchaik, 2021, Chembiochem : a European journal of chemical biology.

Oligosaccharide Synthesis on Controlled-Pore Glass as Solid Phase Material

J. Rademann, A. Heckel, R. Schmidt, 1998 .

Extra- and Intracellular Imaging of Human Matrix Metalloprotease 11 (hMMP-11) with a Cell-penetrating FRET Substrate*

J. Rademann, B. Meyer, Sina Meyer, 2012, The Journal of Biological Chemistry.

Discovery of Mycobacterium Tuberculosis Protein Tyrosine Phosphatase A (MptpA) Inhibitors Based on Natural Products and a Fragment‐Based Approach

K. Saxena, H. Schwalbe, T. Langer, 2005, Chembiochem : a European journal of chemical biology.

The Potential of P1 Site Alterations in Peptidomimetic Protease Inhibitors as Suggested by Virtual Screening and Explored by the Use of CC‐Coupling Reagents

G. Klebe, C. Sotriffer, A. Evers, 2006, ChemMedChem.

Dual Action of Sulfated Hyaluronan on Angiogenic Processes in Relation to Vascular Endothelial Growth Factor-A

S. Djordjević, D. Scharnweber, M. Schnabelrauch, 2019, Scientific Reports.

Biological Characterization, Mechanistic Investigation and Structure‐Activity Relationships of Chemically Stable TLR2 Antagonists

M. Tiemann, J. Rademann, M. Grabowski, 2020, ChemMedChem.

Identification of a pyrogallol derivative as a potent and selective human TLR2 antagonist by structure‐based virtual screening

J. Rademann, M. Grabowski, M. Bermudez, 2018, Biochemical pharmacology.

Structural insights into the modulation of PDGF/PDGFR-β complexation by hyaluronan derivatives

J. Dürig, J. Rademann, V. Hintze, 2021, Biological chemistry.

Mapping Protein–Protein Interactions of the Resistance-Related Bacterial Zeta Toxin–Epsilon Antitoxin Complex (ε2ζ2) with High Affinity Peptide Ligands Using Fluorescence Polarization

P. Zielenkiewicz, J. Rademann, M. I. Fernández-Bachiller, 2016, Toxins.

Shp2 signaling suppresses senescence in PyMT‐induced mammary gland cancer in mice

B. Györffy, W. Birchmeier, B. Győrffy, 2015, The EMBO journal.

Small-Molecule Scaffolds for CYP51 Inhibitors Identified by High-Throughput Screening and Defined by X-Ray Crystallography

M. Waterman, S. Kaufmann, H. Oschkinat, 2007, Antimicrobial Agents and Chemotherapy.

Stereospecific Synthesis of Chiral 2,3‐Dihydro‐1,4‐benzodithiine and Methyl‐2,3‐dihydro‐1,4‐benzodithiine Derivatives and their Toxic Effects on Trypanosoma brucei

M. Duszenko, J. Rademann, W. Voelter, 2005, Chembiochem : a European journal of chemical biology.

Sulfated Hyaluronan Derivatives Modulate TGF-β1:Receptor Complex Formation: Possible Consequences for TGF-β1 Signaling

S. Samsonov, D. Scharnweber, M. Schnabelrauch, 2017, Scientific Reports.

SPOCC-194, a new high functional group density PEG-based resin for solid-phase organic synthesis.

M. Grøtli, T. Groth, M. Meldal, 2002, Journal of combinatorial chemistry.

Chemoenzymatic Synthesis of Nonasulfated Tetrahyaluronan with a Paramagnetic Tag for Studying Its Complex with Interleukin-10.

D. Huster, J. Rademann, J. Schiller, 2016, Chemistry.

Addition to Carbon–Hetero Multiple Bonds

G. Jung, J. Rademann, P. Grosche, 2005 .

Side-Chain Modification of Peptides Using a Phosphoranylidene Amino Acid.

Ahsanullah, J. Rademann, Enaam Masri, 2020, Organic letters.

Benzyl Mono-P-Fluorophosphonate and Benzyl Penta-P-Fluorophosphate Anions Are Physiologically Stable Phosphotyrosine Mimetics and Inhibitors of Protein Tyrosine Phosphatases.

J. Rademann, Matteo Accorsi, Stefan Wagner, 2017, Chemistry.

C-type lectin receptor DCIR modulates immunity to tuberculosis by sustaining type I interferon signaling in dendritic cells

F. Verreck, J. Rademann, G. Lugo-Villarino, 2017, Proceedings of the National Academy of Sciences.

Coupling to Polymeric Scaffolds Stabilizes Biofunctional Peptides for Intracellular Applications

R. Brock, J. Rademann, W. Verdurmen, 2011, Molecular Pharmacology.

The structural investigation of glycosaminoglycan binding to CXCL12 displays distinct interaction sites.

Stephan Theisgen, D. Huster, S. Samsonov, 2016, Glycobiology.

Discovery, Structure–Activity Relationship Studies, and Crystal Structure of Nonpeptide Inhibitors Bound to the Shank3 PDZ Domain

U. Heinemann, A. Diehl, H. Oschkinat, 2011, ChemMedChem.

Author Correction: Sulfated glycosaminoglycans inhibit transglutaminase 2 by stabilizing its closed conformation

J. Rademann, M. T. Pisabarro, U. Hempel, 2022, Scientific Reports.

Sulfated glycosaminoglycans inhibit transglutaminase 2 by stabilizing its closed conformation

J. Rademann, M. T. Pisabarro, U. Hempel, 2022, Scientific Reports.

Epitope-mapping of transglutaminase with parallel label-free optical detection.

G. Gauglitz, G. Jung, J. Rademann, 2002, Biosensors & bioelectronics.

Phenylthiomethyl Ketone-Based Fragments Show Selective and Irreversible Inhibition of Enteroviral 3C Proteases.

J. Rademann, R. Schulz, C. Arkona, 2018, Journal of Medicinal Chemistry.

Insights into structure, affinity, specificity, and function of GAG-protein interactions through the chemoenzymatic preparation of defined sulfated oligohyaluronans

J. Dürig, J. Rademann, J. Schiller, 2021, Biological chemistry.

Oxoammonium Resins as Metal-Free, Highly Reactive, Versatile Polymeric Oxidation Reagents.

G. Jung, J. Rademann, G. Nicholson, 2001, Angewandte Chemie.

Identification of intracellular glycosaminoglycan-interacting proteins by affinity purification mass spectrometry

J. Dürig, M. Schnabelrauch, J. Rademann, 2021, Biological chemistry.

Corrigendum to: Off‐target inhibition by active site‐targeting SHP2 inhibitors

B. Neel, J. Rademann, Ryouhei Tsutsumi, 2019, FEBS Open Bio.

Integration of C-Acylation in the Solid-Phase Synthesis of Peptides and Peptidomimetics employing Meldrum’s Acid, Phosphorus and Sulfur Ylides

J. Rademann, Abbas Hassan, A. Ahsanullah, 2021, Synthesis.

Rational engineering of glycosaminoglycan-based Dickkopf-1 scavengers to improve bone regeneration.

M. Schnabelrauch, J. Rademann, M. T. Pisabarro, 2023, Biomaterials.

Characterization of defined sulfated heparin-like oligosaccharides by electrospray ionization ion trap mass spectrometry.

J. Rademann, J. Schiller, Sebastian Köhling, 2020, Journal of mass spectrometry : JMS.

Peptide-Bismuth Bicycles: In Situ Access to Stable Constrained Peptides with Superior Bioactivity.

J. Rademann, Christoph Nitsche, Saan Voss, 2021, Angewandte Chemie.

Acylated cholesteryl galactosides are ubiquitous glycolipid antigens among Borrelia burgdorferi sensu lato.

R. Schumann, U. Zähringer, J. Rademann, 2011, FEMS immunology and medical microbiology.

Kinetics, Thermodynamics, and Structural Effects of Quinoline-2-Carboxylates, Zinc-Binding Inhibitors of New Delhi Metallo-β-lactamase-1 Re-sensitizing Multidrug-Resistant Bacteria for Carbapenems.

J. Sticht, H. Leiros, M. Mielke, 2023, Journal of medicinal chemistry.

Small-molecule inhibitors of the PDZ domain of Dishevelled 1 proteins interrupt Wnt signalling 2 3

W. Birchmeier, U. Heinemann, A. Diehl, 2021 .

Syntheses of defined sulfated oligohyaluronans reveal structural effects, diversity and thermodynamics of GAG–protein binding

J. Rademann, J. Schiller, Joanna Blaszkiewicz, 2018, Chemical science.

J. Waltenberger, D. Scharnweber, M. Schnabelrauch, 2017, ACS applied materials & interfaces.

Incorporation of Amino Acids with Long-Chain Terminal Olefins into Proteins

P. Herdewijn, N. Budisa, J. Rademann, 2016, Molecules.

New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.

C. Pérez, J. Rademann, M. I. Fernández-Bachiller, 2012, Journal of medicinal chemistry.

Polymer‐bound alkyltriazenes for mild racemization‐free esterification of amino acid and peptide derivatives

G. Jung, J. Rademann, Joachim Smerdka, 2004, Journal of peptide science : an official publication of the European Peptide Society.

Benzoylphosphonate-based photoactive phosphopeptide mimetics for modulation of protein tyrosine phosphatases and highly specific labeling of SH2 domains.

J. Rademann, A. Schütz, M. Lisurek, 2012, Angewandte Chemie.