R. Raftery

发表

Chitosan for Gene Delivery and Orthopedic Tissue Engineering Applications

F. O'Brien, R. Raftery, S. Cryan, 2013, Molecules.

In vitro vascularization of tissue engineered constructs by non-viral delivery of pro-angiogenic genes.

F. O'Brien, R. Reis, L. D. da Silva, 2021, Biomaterials science.

Highly versatile cell-penetrating peptide loaded scaffold for efficient and localised gene delivery to multiple cell types: From development to application in tissue engineering.

K. Shakesheff, F. O'Brien, J. Dixon, 2019, Biomaterials.

Delivery of the improved BMP‐2‐Advanced plasmid DNA within a gene‐activated scaffold accelerates mesenchymal stem cell osteogenesis and critical size defect repair

F. O'Brien, H. Redl, R. Raftery, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Rapid Bone Repair with the Recruitment of CD206+M2-like Macrophages Using Non-Viral Scaffold-Mediated miR-133a Inhibition of Host Cells.

F. O'Brien, R. Raftery, B. Cavanagh, 2020, Acta biomaterialia.

Translating the role of osteogenic-angiogenic coupling in bone formation: Highly efficient chitosan-pDNA activated scaffolds can accelerate bone regeneration in critical-sized bone defects.

F. O'Brien, R. Raftery, S. Cryan, 2017, Biomaterials.

Rapid healing of a critical‐sized bone defect using a collagen‐hydroxyapatite scaffold to facilitate low dose, combinatorial growth factor delivery

F. O'Brien, R. Raftery, S. Cryan, 2019, Journal of tissue engineering and regenerative medicine.

Transfection of autologous host cells in vivo using gene 1 activated scaffolds incorporating star-polypeptides 2

F. O'Brien, R. Raftery, S. Cryan, 2020 .

Pro‐angiogenic impact of SDF‐1&agr; gene‐activated collagen‐based scaffolds in stem cell driven angiogenesis

F. O'Brien, A. L. Laiva, R. Raftery, 2018, International journal of pharmaceutics.

Multifunctional biomaterials from the sea: Assessing the effects of chitosan incorporation into collagen scaffolds on mechanical and biological functionality.

Brian F. Woods, F. O'Brien, R. Reis, 2016, Acta biomaterialia.

Delivering Nucleic‐Acid Based Nanomedicines on Biomaterial Scaffolds for Orthopedic Tissue Repair: Challenges, Progress and Future Perspectives

F. O'Brien, R. Raftery, S. Cryan, 2016, Advanced materials.

Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates.

F. O'Brien, R. Raftery, S. Heilshorn, 2018, Biomaterials.

microRNA Modulation

F. O'Brien, R. Raftery, C. Curtin, 2019, Cell Engineering and Regeneration.

In vitro efficacy of a gene-activated nerve guidance conduit incorporating non-viral PEI-pDNA nanoparticles carrying genes encoding for NGF, GDNF and c-Jun.

F. O'Brien, R. Raftery, W. Lackington, 2018, Acta biomaterialia.

Development of a gene-activated scaffold platform for tissue engineering applications using chitosan-pDNA nanoparticles on collagen-based scaffolds.

F. O'Brien, R. Raftery, S. Cryan, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Accelerating bone healing in vivo by harnessing the age-altered activation of c-Jun N-terminal kinase 3.

F. O'Brien, R. Raftery, D. Murray, 2020, Biomaterials.

Mechanobiology-informed regenerative medicine: Dose-controlled release of placental growth factor from a functionalized collagen-based scaffold promotes angiogenesis and accelerates bone defect healing.

Eamon J. Sheehy, F. O'Brien, R. Raftery, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Activation of the SOX‐5, SOX‐6, and SOX‐9 Trio of Transcription Factors Using a Gene‐Activated Scaffold Stimulates Mesenchymal Stromal Cell Chondrogenesis and Inhibits Endochondral Ossification

F. O'Brien, R. Raftery, Gang Chen, 2020, Advanced healthcare materials.

Transfection of autologous host cells in vivo using gene activated collagen scaffolds incorporating star-polypeptides.

F. O'Brien, R. Raftery, S. Cryan, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Bioinspired Star-Shaped Poly(l-lysine) Polypeptides: Efficient Polymeric Nanocarriers for the Delivery of DNA to Mesenchymal Stem Cells.

F. O'Brien, J. Simpson, A. Panarella, 2018, Molecular pharmaceutics.

Nanoparticle-mediated siRNA delivery assessed in a 3D co-culture model simulating prostate cancer bone metastasis.

Caitriona M O' Driscoll, R. Darcy, R. Raftery, 2016, International journal of pharmaceutics.

Directed differentiation of human pluripotent stem cells into articular cartilage reveals effects caused by absence of WISP3, the gene responsible for Progressive Pseudorheumatoid Arthropathy of Childhood

M. Warman, R. Raftery, A. M. Craft, 2023, bioRxiv.

Scaffold‐Based Delivery of Nucleic Acid Therapeutics for Enhanced Bone and Cartilage Repair

F. O'Brien, C. O’Driscoll, R. Raftery, 2019, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Gene activated scaffolds incorporating star-shaped polypeptide-pDNA nanomedicines accelerate bone tissue regeneration in vivo.

F. O'Brien, R. Raftery, S. Cryan, 2021, Biomaterials science.

Dual Scaffold Delivery of miR-210 Mimic and miR-16 Inhibitor Enhances Angiogenesis and Osteogenesis to Accelerate Bone Healing.

R. Raftery, B. Cavanagh, C. Curtin, 2023, Acta biomaterialia.

Development of a gene-activated scaffold platform for tissue engineering applications using chitosan-pDNA nanoparticles on collagen-based scaffolds.

F. O'Brien, R. Raftery, S. Cryan, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Directed differentiation of human pluripotent stem cells into articular cartilage reveals effects caused by absence of WISP3, the gene responsible for progressive pseudorheumatoid arthropathy of childhood

R. Raftery, A. M. Craft, Chaochang Li, 2023, Annals of the Rheumatic Diseases.