P. Hänninen

发表

Core-shell designs of photoluminescent nanodiamonds with porous silica coatings for bioimaging and drug delivery II: application.

Hua Jiang, Sami Koho, Tuomas Näreoja, 2013, Nanoscale.

Continuous wave excitation two‐photon fluorescence microscopy

Pekka Hänninen, Stefan W. Hell, Erkki Soini, 1994 .

Two-photon excitation 4Pi confocal microscope: enhanced axial resolution microscope for biological research

Pekka Hänninen, Stefan W. Hell, Christoph Cremer, 1995 .

Protein quantification using resonance energy transfer between donor nanoparticles and acceptor quantum dots.

Pekka Hänninen, Hans-Gerd Löhmannsröben, Harri Härmä, 2013, Analytical chemistry.

Study on nonspecificity of an immuoassay using Eu-doped polystyrene nanoparticle labels.

Tuomas Näreoja, P. Hänninen, H. Härmä, 2009, Journal of immunological methods.

Time-resolved fluorescence-based assay for rapid detection of Escherichia coli.

P. Hänninen, Janne Kulpakko, Kari Kopra, 2015, Analytical biochemistry.

Ultra Sensitive Bioaffinity Assay for Micro Volumes

Pekka Hänninen, Erkki Soini, Jori Soukka, 2000 .

Evaluation of the TPX MRSA assay for the detection of methicillin-resistant Staphylococcus aureus

P. Hänninen, H. Härmä, P. Huovinen, 2011, European Journal of Clinical Microbiology & Infectious Diseases.

Rapid Method for Detection of Influenza A and B Virus Antigens by Use of a Two-Photon Excitation Assay Technique and Dry-Chemistry Reagents

P. Hänninen, R. Vainionpää, J. Koskinen, 2007, Journal of Clinical Microbiology.

Detection methods of microsphere based single-step bioaffinity and in vitro diagnostics assays.

J. Soini, P. Hänninen, M. Waris, 2004, Journal of pharmaceutical and biomedical analysis.

Nonspecific particle-based method with two-photon excitation detection for sensitive protein quantification and cell counting.

P. Hänninen, H. Härmä, S. Pihlasalo, 2013, Analytical chemistry.

Sensitive method for determination of protein and cell concentrations based on competitive adsorption to nanoparticles and time-resolved luminescence resonance energy transfer between labeled proteins.

P. Hänninen, H. Härmä, S. Pihlasalo, 2012, Analytical chemistry.

Single-label time-resolved luminescence assay for estrogen receptor--ligand binding.

P. Hänninen, H. Härmä, Merja Lahdenranta, 2011, Analytical biochemistry.

Advanced Cellulose Fibers for Efficient Immobilization of Enzymes.

T. Heinze, Tuomas Näreoja, E. Fazeli, 2016, Biomacromolecules.

A Homogeneous Single-Label Time-Resolved Fluorescence cAMP Assay

P. Hänninen, H. Härmä, U. Petäjä-Repo, 2011, Journal of biomolecular screening.

Synthesis and characterization of core-shell europium(III)-silica nanoparticles

P. Hänninen, H. Härmä, C. Graf, 2008 .

Two-Photon Excitation in Fluorescence Polarization Receptor-Ligand Binding Assay

J. Soini, P. Härkönen, P. Hänninen, 2005, Journal of biomolecular screening.

A low resource setting oral lesion screening tool

D. Desai, P. Hänninen, R. Desai, 2016 .

A Fluorometric Fullerenol Sensor for Rapid Detection of Ionic and Non-Ionic Surfactants

P. Hänninen, H. Härmä, S. Pihlasalo, 2010 .

Two‐photon Excitation Fluorescence Bioassays

J. Soini, P. Hänninen, J. Soukka, 2008, Annals of the New York Academy of Sciences.

Sensitive luminometric method for protein quantification in bacterial cell lysate based on particle adsorption and dissociation of chelated europium.

P. Hänninen, H. Härmä, S. Pihlasalo, 2012, Analytical chemistry.

Multiparametric homogeneous method for identification of ligand binding to G protein-coupled receptors: receptor-ligand binding and β-arrestin assay.

P. Hänninen, H. Härmä, Piia Mikkonen, 2013, Analytical chemistry.

Rapid detection of trace amounts of surfactants using nanoparticles in fluorometric assays.

L. Bergström, P. Hänninen, H. Härmä, 2010, Nanoscale.

Rapid time-resolved luminescence based screening of bacteria in urine with luminescence modulating biosensing phages.

P. Hänninen, K. Rantakokko-jalava, E. Eerola, 2019, Analytical biochemistry.

In vitro model of bone to facilitate measurement of adhesion forces and super-resolution imaging of osteoclasts

P. Lehenkari, J. Peltonen, Tuomas Näreoja, 2016, Scientific Reports.

Academic innovation: are we truly ready for it?

P. Hänninen, 2015 .

Fuzzy liquid analysis by an array of nonspecifically interacting reagents: the taste of fluorescence.

M. Sandell, A. Knaapila, P. Hänninen, 2013, Journal of the American Chemical Society.

Quantitative detection of cell surface protein expression by time-resolved fluorimetry.

J. Soini, P. Härkönen, P. Hänninen, 2007, Luminescence : the journal of biological and chemical luminescence.

Resolving fluorescence beads at 100–200 nm axial distance with a two-photon 4Pi-microscope operating in the near infrared

S. Hell, P. Hänninen, M. Schrader, 1995 .

Optimization of multi-photon event discrimination levels using Poisson statistics.

J. Soini, P. Hänninen, A. Virkki, 2004, Optics express.

Nonlinear fluorescence through intermolecular energy transfer and resolution increase in fluorescence microscopy

S. Hell, A. Schönle, P. Hänninen, 1999, Annalen der Physik.

Method for determination of polyethylene glycol molecular weight.

P. Hänninen, H. Härmä, S. Pihlasalo, 2015, Analytical chemistry.

Sensitive fluorometric nanoparticle assays for cell counting and viability.

P. Hänninen, H. Härmä, S. Pihlasalo, 2010, Analytical chemistry.

Simple nanoparticle-based luminometric method for molecular weight determination of polymeric compounds.

P. Hänninen, H. Härmä, S. Pihlasalo, 2014, Analytical chemistry.

Multiparametric luminescence method for quantitative cell surface protein expression analysis and imaging.

J. Soini, P. Härkönen, P. Hänninen, 2011, Journal of immunological methods.

Light microscopy (communication arising): Beyond the diffraction limit

P. Hänninen, 2002, Nature.

Thin solid europium(III) dye layers as donors in time-resolved fluorescence resonance energy transfer assays

T. Kololuoma, P. Hänninen, H. Härmä, 2009 .

Lanthanide luminescence : photophysical, analytical and biological aspects

Pekka Hänninen, Harri Härmä, P. Hänninen, 2011 .

UV–Vis and NIR Fluorescence Spectroscopy

G. Patonay, P. Hänninen, Garfield Beckford, 2014 .

Modelling of multi-component immunoassay kinetics - A new node-based method for simulation of complex assays.

Pekka Hänninen, P. Hänninen, Pilvi J Ylander, 2010, Biophysical chemistry.

Syntheses of Novel Dipyrrylmethene-BF2 Dyes and Their Performance as Labels in Two-Photon Excited Fluoroimmunoassay

P. Hänninen, A. Soini, N. Meltola, 2004, Journal of Fluorescence.

Comparison of homogeneous single-label fluorometric binding assays: fluorescence polarization and dual-parametric quenching resonance energy transfer technique.

P. Hänninen, H. Härmä, I. Hemmilä, 2010, Analytical chemistry.

Method for estimation of protein isoelectric point.

Pekka Hänninen, Harri Härmä, P. Hänninen, 2012, Analytical chemistry.

Ultrasonic enrichment of microspheres for ultrasensitive biomedical analysis in confocal laser-scanning fluorescence detection

Pekka Hänninen, Hans M. Hertz, Juha Toivonen, 2004 .

Density and function of actin-microdomains in healthy and NF1 deficient osteoclasts revealed by the combined use of atomic force and stimulated emission depletion microscopy

J. Eriksson, J. Peltonen, K. Vienola, 2019, Journal of Physics D: Applied Physics.

Nanometric features of myosin filaments extracted from a single muscle fiber to uncover the mechanisms underlying organized motility.

B. Jena, L. Larsson, Tuomas Näreoja, 2015, Archives of biochemistry and biophysics.

New separation-free assay technique for SNPs using two-photon excitation fluorometry.

R. Lahesmaa, J. Soini, P. Hänninen, 2004, Nucleic acids research.

Automated cell tracking using StarDist and TrackMate

Romain F. Laine, Guillaume Jacquemet, Elnaz Fazeli, 2020, bioRxiv.

High-throughput screening of colonization samples for methicillin-resistant Staphylococcus aureus

P. Hänninen, H. Härmä, P. Huovinen, 2013, Scandinavian journal of infectious diseases.

Nonlinear filtering in improving the image quality of confocal fluorescent images

Pekka Hänninen, Juha Salo, Ernst H. K. Stelzer, 1991, Machine Vision and Applications.

Non-competitive aptamer-based quenching resonance energy transfer assay for homogeneous growth factor quantification.

P. Hänninen, H. Härmä, Markku Syrjänpää, 2014, The Analyst.

Non-specific Liquid Fingerprinting in Monitoring the Hygiene and Authenticity of Milk

P. Hänninen, Janne Kulpakko, Anita Rozwandowicz-Jansen, 2018, Food Analytical Methods.

Super-sensitive time-resolved fluoroimmunoassay for thyroid-stimulating hormone utilizing europium(III) nanoparticle labels achieved by protein corona stabilization, short binding time, and serum preprocessing

J. Rosenholm, Tuomas Näreoja, P. Hänninen, 2017, Analytical and Bioanalytical Chemistry.

Multiple sized europium(III) chelate-dyed polystyrene particles as donors in FRET - an application for sensitive protein quantification utilizing competitive adsorption.

Pekka Hänninen, Tero Soukka, Harri Härmä, 2009, The Analyst.

Nanoparticle Labels in Bioaffinity Assays by Antti Valanne

J. Peltonen, T. Soukka, P. Hänninen, 2009 .

A long-arm autocorrelator for measurement of pico- to nanosecond laser pulse widths

J. Soini, P. Hänninen, T. Stenholm, 2004 .

Impact of surface defects and denaturation of capture surface proteins on nonspecific binding in immunoassays using antibody-coated polystyrene nanoparticle labels.

Tuomas Näreoja, Harri Härmä, Jouko Peltonen, 2009, Journal of immunological methods.

Photo-induced ultrasound microscopy for photo-acoustic imaging of non-absorbing specimens

Sami Koho, Elena Tcarenkova, Pekka Hänninen, 2017, Applications of Optics and Photonics.

Two- and multiphoton excitation of conjugate-dyes using a continuous wave laser

Pekka Hänninen, Stefan W. Hell, Lotta Lehtela, 1996 .

Fluorescent nanoparticles as labels for immunometric assay of C-reactive protein using two-photon excitation assay technology.

Jonne Vaarno, J. Soini, P. Hänninen, 2004, Analytical biochemistry.

Intracellular Trafficking of Fluorescent Nanodiamonds and Regulation of Their Cellular Toxicity

N. Prabhakar, J. Rosenholm, P. Hänninen, 2017, ACS omega.

A New Simple Cell-Based Homogeneous Time-Resolved Fluorescence QRET Technique for Receptor-Ligand Interaction Screening

M. Perälä, P. Hänninen, H. Härmä, 2009, Journal of biomolecular screening.

Effect of Polystyrene Microsphere Surface to Fluorescence Lifetime Under Two-Photon Excitation

P. Hänninen, J. Toivonen, N. Meltola, 2006, Journal of Fluorescence.

A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction

P. Hänninen, D. Abankwa, S. Veltel, 2014, Analytical and Bioanalytical Chemistry.

Time-Resolved Fluorescence Immunoassay for C-Reactive Protein Using Colloidal Semiconducting Nanoparticles

Wolfgang J. Parak, Pekka Hänninen, Juha Toivonen, 2011, Sensors.

Functionalization of graphene oxide nanostructures improves photoluminescence and facilitates their use as optical probes in preclinical imaging.

O. Shenderova, S. Burikov, N. Prabhakar, 2015, Nanoscale.

Light microscopy: beyond the diffraction limit.

Pekka Hänninen, P. Hänninen, 2002, Nature.

Photon-burst analysis in two-photon fluorescence excitation flow cytometry.

P E Hänninen, J. Soini, P. Hänninen, 1999, Cytometry.

Kinetics of bioconjugate nanoparticle label binding in a sandwich-type immunoassay

V. Hytönen, F. Kienberger, Tuomas Näreoja, 2013, Analytical and Bioanalytical Chemistry.

Two-photon fluorescence excitation in detection of biomolecules.

P E Hänninen, J. Soini, P. Hänninen, 2000, Biochemical Society transactions.

Time-Domain Measurements

Pekka Hänninen, Ari Kuusisto, P. Hänninen, 2011 .

Annular aperture two-photon excitation microscopy

S. Hell, P. Hänninen, A. Kuusisto, 1995 .

Novel Method for Real-Time Monitoring of Scale Control Products at the Site of Use

James Johnstone, Susanna Toivonen, Rick Griffin, 2014, OSS 2014.

A homogeneous single-label quenching resonance energy transfer assay for a δ-opioid receptor-ligand using intact cells.

P. Hänninen, H. Härmä, U. Petäjä-Repo, 2013, The Analyst.

Image formation and data acquisition in a stage scanning 4Pi confocal fluorescence microscope.

S. Hell, J. Soini, P. Hänninen, 1997, Applied optics.

Homogeneous single-label biochemical Ras activation assay using time-resolved luminescence.

P. Hänninen, S. Veltel, H. Härmä, 2011, Analytical chemistry.

Cell-based beta2-adrenergic receptor-ligand binding assay using synthesized europium-labeled ligands and time-resolved fluorescence.

Pekka Hänninen, Mirva Lehmusto, Harri Härmä, 2009, Analytical biochemistry.

Two‐photon excitation fluorescence microscopy using a semiconductor laser

Pekka Hänninen, Martin Schrader, Stefan W. Hell, 1995 .

Image Quality Ranking Method for Microscopy

John E. Eriksson, Sami Koho, Elnaz Fazeli, 2016, Scientific Reports.

Theoretical assessments of errors in rapid immunoassays-how critical is the exact timing and reagent concentrations?

J. Soini, P. Hänninen, Pilvi J Ylander, 2006, Biophysical Chemistry.

A new microvolume technique for bioaffinity assays using two-photon excitation

Pekka Hänninen, Erkki Soini, Jori Soukka, 2000, Nature Biotechnology.

Reaction kinetics of a two-photon excitation microparticle based immunoassay--from modelling to practice.

P. Hänninen, E. Soini, M. Waris, 2003, Biophysical chemistry.

Nonlinear fluorescence through intermolecular energy transfer and resolution increase in fluorescence microscopy

Pekka Hänninen, Stefan W. Hell, Andreas Schönle, 1999 .

Gold nanoparticle printed coverslips to facilitate fluorescence-TEM correlative microscopy.

A. Määttänen, J. Peltonen, N. Prabhakar, 2018, Microscopy.

Two-Photon Excited Fluorescence Energy Transfer: A Study Based on Oligonucleotide Rulers

P. Hänninen, J. Toivonen, Rina Wahlroos, 2006, Journal of Fluorescence.

Homogeneous GTP Binding Assay Employing QRET Technology

M. Scheinin, P. Hänninen, H. Härmä, 2010, Journal of biomolecular screening.

Two- and multiphoton detection as an imaging mode and means of increasing the resolution in far-field light microscopy: A study based on photon-optics

S. Hell, P. Hänninen, J. Soukka, 1995 .

Resolving fluorescence beads at 100–200 nm axial distance with a two-photon 4Pi-microscope operating in the near infrared (Optics Comm. 120 (1995) 129)

S. Hell, P. Hänninen, M. Schrader, 1996 .

Pulsed and cw confocal microscopy : a comparison of resolution and contrast

S. Hell, T. Wilson, P. Hänninen, 1994 .

Refractive‐index‐induced aberrations in two‐photon confocal fluorescence microscopy

Pekka Hänninen, Stefan W. Hell, Erkki Soini, 1994 .

Biophysical Properties of Bifunctional Phage-Biosensor

P. Hänninen, Janne Kulpakko, Elizabeth Cudjoe, 2023, Viruses.

Axial super-resolution by mirror-reflected stimulated emission depletion microscopy

Tuomas Näreoja, T. Deguchi, S. Koho, 2014 .

Detecting disease associated biomarkers by luminescence modulating phages

A. Rannikko, P. Hänninen, Janne Kulpakko, 2022, Scientific Reports.

Methicillin-Resistant Staphylococcus aureus Screening by Online Immunometric Monitoring of Bacterial Growth under Selective Pressure

P. Hänninen, J. Vuopio‐Varkila, P. Huovinen, 2009, Antimicrobial Agents and Chemotherapy.

Two-photon excitation fluorometric measurement of homogeneous microparticle immunoassay for C-reactive protein.

Erkki Soini, J. Soini, P. Hänninen, 2002, Analytical biochemistry.

Two-photon excitation microfluorometer for multiplexed single-step bioaffinity assays

Pekka Hänninen, Erkki Soini, Jori Soukka, 2002 .

Low cost lasers challenge ultrafast systems in two-photon excitation applications

J. Soini, P. Hänninen, J. Vaarno, 2003 .

STED-TEM Correlative Microscopy Leveraging Nanodiamonds as Intracellular Dual-Contrast Markers.

N. Prabhakar, J. Rosenholm, Tuomas Näreoja, 2018, Small.