M. Benderdour

发表

Linear polyethylenimine produced by partial acid hydrolysis of poly(2-ethyl-2-oxazoline) for DNA and siRNA delivery in vitro

Xiaoling Zhang, Q. Shi, J. Fernandes, 2013, International journal of nanomedicine.

Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy.

J. Fernandes, M. Benderdour, Sania Mansouri, 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Evidence Supporting the Safety of Pegylated Diethylaminoethyl-Chitosan Polymer as a Nanovector for Gene Therapy Applications

J. Fernandes, M. Benderdour, M. J. Tiera, 2020, International journal of nanomedicine.

Nanoparticles for Gene Therapy

Xiaoling Zhang, Q. Shi, J. Fernandes, 2021 .

Chitosan-DNA/siRNA Nanoparticles for Gene Therapy

Xiaoling Zhang, Q. Shi, J. Fernandes, 2011 .

Involvement of ICAM-1 in bone metabolism: a potential target in the treatment of bone diseases?

Q. Shi, J. Fernandes, M. Benderdour, 2005, Expert opinion on biological therapy.

Chitosan-Based Nanogels: Synthesis and Toxicity Profile for Drug Delivery to Articular Joints

J. Fernandes, M. Benderdour, F. Moldovan, 2022, Nanomaterials.

Perturbation of adhesion molecule-mediated chondrocyte-matrix interactions by 4-hydroxynonenal binding: implication in osteoarthritis pathogenesis

H. Fahmi, L. Macqueen, M. Buschmann, 2010, Arthritis Research & Therapy.

The role of resolvin D1 in the regulation of inflammatory and catabolic mediators in osteoarthritis

H. Fahmi, Q. Shi, J. Fernandes, 2016, Inflammation Research.

Lysine-specific demethylase 1-mediated demethylation of histone H3 lysine 9 contributes to interleukin 1β-induced microsomal prostaglandin E synthase 1 expression in human osteoarthritic chondrocytes

H. Afif, J. Pelletier, J. Martel-Pelletier, 2014, Arthritis Research & Therapy.

Valproic Acid Suppresses Interleukin-1ß-induced Microsomal Prostaglandin E2 Synthase-1 Expression in Chondrocytes Through Upregulation of NAB1

J. Pelletier, J. Martel-Pelletier, M. Kapoor, 2011, The Journal of Rheumatology.

Differential regulation of cyclooxygenase‐2 and inducible nitric oxide synthase by 4‐hydroxynonenal in human osteoarthritic chondrocytes through ATF‐2/CREB‐1 transactivation and concomitant inhibition of NF‐κB signaling cascade

J. D. Di Battista, H. Fahmi, Q. Shi, 2007, Journal of cellular biochemistry.

Characterization of folate-chitosan-DNA nanoparticles for gene therapy.

Q. Shi, J. Fernandes, M. Benderdour, 2006, Biomaterials.

19 Chitosan-DNA / siRNA Nanoparticles for Gene Therapy

Xiaoling Zhang, Q. Shi, J. Fernandes, 2012 .

Diethylaminoethyl- chitosan as an efficient carrier for siRNA delivery: Improving the condensation process and the nanoparticles properties.

Q. Shi, J. Fernandes, M. Benderdour, 2018, International journal of biological macromolecules.

Decreased cardiac mitochondrial NADP+-isocitrate dehydrogenase activity and expression: a marker of oxidative stress in hypertrophy development.

C. Des Rosiers, B. Comte, M. Benderdour, 2004, American journal of physiology. Heart and circulatory physiology.

Elucidation of molecular mechanisms underlying the protective effects of thymoquinone against rheumatoid arthritis

H. Fahmi, Q. Shi, J. Fernandes, 2011, Journal of cellular biochemistry.

Elucidating the Role of Protandim and 6‐Gingerol in Protection Against Osteoarthritis

J. Martel-Pelletier, H. Fahmi, B. Lussier, 2017, Journal of cellular biochemistry.

Can altered production of interleukin-1beta, interleukin-6, transforming growth factor-beta and prostaglandin E(2) by isolated human subchondral osteoblasts identify two subgroups of osteoarthritic patients.

J. Martel-Pelletier, J. Pelletier, M. Benderdour, 2002, Osteoarthritis and cartilage.

Expression of ICAM-1 by osteoblasts in healthy individuals and in patients suffering from osteoarthritis and osteoporosis.

Q. Shi, J. Fernandes, M. Benderdour, 2004, Bone.

Deletion of 12/15-lipoxygenase accelerates the development of aging-associated and instability-induced osteoarthritis.

J. Martel-Pelletier, J. Pelletier, H. Fahmi, 2017, Osteoarthritis and cartilage.

Expression of Peroxisome Proliferator-activated Receptors α, β, γ, and H- and L-Prostaglandin D Synthase During Osteoarthritis in the Spontaneous Hartley Guinea Pig and Experimental Dog Models

H. Afif, J. Pelletier, J. Martel-Pelletier, 2013, The Journal of Rheumatology.

Effect of boric acid solution on cartilage metabolism.

M. Benderdour, P. Nabet, B. Dousset, 1997, Biochemical and biophysical research communications.

Double-grafted chitosans as siRNA nanocarriers: effects of diisopropylethylamine substitution and labile-PEG coating

J. Fernandes, M. Benderdour, M. J. Tiera, 2022, Journal of Nanostructure in Chemistry.

In vivo therapeutic efficacy of TNFα silencing by folate-PEG-chitosan-DEAE/siRNA nanoparticles in arthritic mice

Xiaoling Zhang, Q. Shi, J. Fernandes, 2018, International journal of nanomedicine.

An overview of the role of lipid peroxidation-derived 4-hydroxynonenal in osteoarthritis

H. Fahmi, Q. Shi, J. Fernandes, 2017, Inflammation Research.

Interleukin 17 (IL-17) induces collagenase-3 production in human osteoarthritic chondrocytes via AP-1 dependent activation: differential activation of AP-1 members by IL-17 and IL-1beta.

J. Pelletier, J. Martel-Pelletier, J. D. Di Battista, 2002, The Journal of rheumatology.

Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: a possible role in rheumatoid arthritis.

J. Pelletier, J. Martel-Pelletier, J. D. Di Battista, 2000, Arthritis and rheumatism.

Stimulation of 92-kd gelatinase (matrix metalloproteinase 9) production by interleukin-17 in human monocyte/macrophages: a possible role in rheumatoid arthritis.

J. Pelletier, J. Martel-Pelletier, J. D. Di Battista, 2000, Arthritis and rheumatism.

Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes

H. Fahmi, Q. Shi, J. Fernandes, 2014, Inflammation Research.

Impact of Degree of Ionization and PEGylation on the Stability of Nanoparticles of Chitosan Derivatives at Physiological Conditions

J. Fernandes, M. Benderdour, M. J. Tiera, 2022, Marine drugs.

L-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis

J. Pelletier, J. Martel-Pelletier, Y. Urade, 2020, Aging.

Inhibition of inducible nitric oxide synthase prevents lipid peroxidation in osteoarthritic chondrocytes

H. Fahmi, Q. Shi, J. Fernandes, 2012, Journal of cellular biochemistry.

Evidence for two distinct pathways in TNFalpha-induced membrane and soluble forms of ICAM-1 in human osteoblast-like cells isolated from osteoarthritic patients.

Q. Shi, J. Fernandes, M. Benderdour, 2007, Osteoarthritis and cartilage.

Boron Modulates Extracellular Matrix and TNFα Synthesis in Human Fibroblasts

M. Benderdour, P. Nabet, B. Dousset, 1998 .

Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes

H. Afif, J. Pelletier, J. Martel-Pelletier, 2012, Arthritis Research & Therapy.

Nuclear receptor retinoid‐related orphan receptor α1 modulates the metabolic activity of human osteoblasts

H. Fahmi, Q. Shi, J. Fernandes, 2011, Journal of cellular biochemistry.

Low molecular weight chitosan conjugated with folate for siRNA delivery in vitro: optimization studies

Xiaoling Zhang, Q. Shi, J. Fernandes, 2012, International journal of nanomedicine.

Efficient Nonviral Gene Therapy Using Folate-Targeted Chitosan-DNA Nanoparticles In Vitro

Xiaoling Zhang, Q. Shi, J. Fernandes, 2012, ISRN pharmaceutics.

Hydrodynamic Delivery of Chitosan-Folate-DNA Nanoparticles in Rats with Adjuvant-Induced Arthritis

Xiaoling Zhang, Q. Shi, J. Fernandes, 2010, Journal of biomedicine & biotechnology.

Hepatocyte growth factor induction of collagenase 3 production in human osteoarthritic cartilage: involvement of the stress-activated protein kinase/c-Jun N-terminal kinase pathway and a sensitive p38 mitogen-activated protein kinase inhibitor cascade.

J. Martel-Pelletier, J. Pelletier, M. Benderdour, 2001, Arthritis and rheumatism.

Covalent binding of 4-hydroxynonenal to matrix metalloproteinase 13 studied by liquid chromatography-mass spectrometry.

M. Benderdour, M. Golizeh, L. Sleno, 2014, Chemical research in toxicology.

Tuning with Phosphorylcholine Grafts Improves the Physicochemical Properties of PLL/pDNA Nanoparticles at Neutral pH

J. Fernandes, M. Benderdour, M. J. Tiera, 2019, Macromolecular Research.

The role of resolvin D1 in the regulation of inflammatory and catabolic mediators in osteoarthritis

H. Fahmi, Q. Shi, J. Fernandes, 2016, Inflammation Research.

New Evidence Implicating 4‐Hydroxynonenal in the Pathogenesis of Osteoarthritis In Vivo

H. Fahmi, Q. Shi, J. Fernandes, 2014, Arthritis & rheumatology.

Peroxisome proliferator-activated receptor γ1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1β in articular chondrocytes

H. Afif, J. Pelletier, J. Martel-Pelletier, 2007, Arthritis research & therapy.

Subchondral and trabecular bone metabolism regulation in canine experimental knee osteoarthritis.

J. Martel-Pelletier, J. Pelletier, Q. Shi, 2005, Osteoarthritis and cartilage.

Pluronic F-127 as a Cell Carrier for Bone Tissue Engineering

Q. Shi, J. Fernandes, M. Benderdour, 2009, Journal of biomaterials applications.

An active role for soluble and membrane intercellular adhesion molecule-1 in osteoclast activity in vitro

Q. Shi, J. Fernandes, M. Benderdour, 2008, Journal of Bone and Mineral Metabolism.

A novel negative regulatory element in the human collagenase-3 proximal promoter region.

J. Pelletier, J. Martel-Pelletier, M. Benderdour, 2002, Biochemical and biophysical research communications.

Effects of boron derivatives on extracellular matrix formation.

M. Benderdour, A. Dicko, B. Dousset, 2000, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

In vivo and in vitro effects of boron and boronated compounds.

M. Benderdour, A. Dicko, F. Belleville, 1998, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Lymphocyte transformation test reveals low prevalence of true metal hypersensitivity among pre-operative total knee arthroplasty patients

J. Fernandes, M. Benderdour, F. Vallières, 2022, Knee Surgery, Sports Traumatology, Arthroscopy.

Mechanisms implicated in the effects of boron on wound healing.

M. Benderdour, P. Nabet, R. Nzietchueng, 2002, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase

H. Fahmi, Q. Shi, J. Fernandes, 2008, Arthritis research & therapy.

Connexin 43 mimetic peptide Gap26 confers protection to intact heart against myocardial ischemia injury

G. Rousseau, M. Benderdour, G. Baroudi, 2010, Pflügers Archiv - European Journal of Physiology.

siRNA therapy for cancer and non-lethal diseases such as arthritis and osteoporosis

Q. Shi, J. Fernandes, K. Dai, 2011, Expert opinion on biological therapy.

Elucidation of mechanisms underlying the protective effects of olive leaf extract against lead-induced neurotoxicity in Wistar rats.

M. Benderdour, M. Slimani, A. Aoues, 2011, The Journal of toxicological sciences.

Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes

H. Fahmi, Shu-Huang Chen, Q. Shi, 2010, Arthritis research & therapy.

University of Montreal Bioassay-guided antidiabetic potentials of Devil’s club (Oplopanax horridus) preparations from the traditional pharmacopeia of the Squamish and other first nations of British Columbia. By Nyruz

M. Benderdour, J. Thibodeau, R. Elahmer, 2018 .

Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis

J. Pelletier, J. Martel-Pelletier, H. Fahmi, 2009, Arthritis research & therapy.

Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2.

H. Afif, J. Pelletier, J. Martel-Pelletier, 2008, Arthritis and rheumatism.

Identification of 4-hydroxynonenal-modified proteins in human osteoarthritic chondrocytes.

J. Fernandes, M. Benderdour, L. Sleno, 2020, Journal of proteomics.

Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis

H. Fahmi, Q. Shi, J. Fernandes, 2012, Arthritis Research & Therapy.

Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal

H. Afif, J. D. Di Battista, H. Fahmi, 2006, Arthritis research & therapy.

Production of lipid peroxidation products in osteoarthritic tissues: new evidence linking 4-hydroxynonenal to cartilage degradation.

Q. Shi, J. Fernandes, M. Benderdour, 2006, Arthritis and rheumatism.

Cardiac Mitochondrial NADP+-isocitrate Dehydrogenase Is Inactivated through 4-Hydroxynonenal Adduct Formation

C. Des Rosiers, B. Comte, M. Benderdour, 2003, Journal of Biological Chemistry.

Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes.

H. Afif, J. Pelletier, J. Martel-Pelletier, 2008, Osteoarthritis and cartilage.

The pathophysiology of immunoporosis: innovative therapeutic targets

J. Fernandes, M. Benderdour, F. Vallières, 2021, Inflammation Research.

Boron modulates extracellular matrix and TNF alpha synthesis in human fibroblasts.

M. Benderdour, P. Nabet, B. Dousset, 1998, Biochemical and biophysical research communications.

Atorvastatin prevents early apoptosis after thoracic spinal cord contusion injury and promotes locomotion recovery

G. Rousseau, M. Déry, M. Benderdour, 2009, Neuroscience Letters.

Escitalopram reduces circulating pro-inflammatory cytokines and improves depressive behavior without affecting sleep in a rat model of post-cardiac infarct depression

R. Godbout, G. Rousseau, M. Benderdour, 2011, Behavioural Brain Research.

Exacerbation of Aging‐Associated and Instability‐Induced Murine Osteoarthritis With Deletion of D Prostanoid Receptor 1, a Prostaglandin D2 Receptor

H. Afif, J. Pelletier, J. Martel-Pelletier, 2017, Arthritis & rheumatology.

Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage

J. Pelletier, J. Martel-Pelletier, H. Fahmi, 2008, Arthritis research & therapy.

Contribution of H3K4 methylation by SET-1A to interleukin-1-induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytes.

J. Pelletier, J. Martel-Pelletier, M. Kapoor, 2011, Arthritis and rheumatism.

Role of Lipocalin‐Type Prostaglandin D Synthase in Experimental Osteoarthritis

J. Pelletier, J. Martel-Pelletier, Y. Urade, 2020, Arthritis & rheumatology.

Association of polymorphisms in the peroxisome proliferator-activated receptor γ gene and osteoarthritis of the knee

H. Afif, J. Raynauld, J. Martel-Pelletier, 2006, Annals of the rheumatic diseases.

Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia.

C. Des Rosiers, B. Comte, M. Benderdour, 2002, American journal of physiology. Heart and circulatory physiology.

Sorbitol-modified hyaluronic acid reduces oxidative stress, apoptosis and mediators of inflammation and catabolism in human osteoarthritic chondrocytes

H. Fahmi, Q. Shi, J. Fernandes, 2014, Inflammation Research.

In vitro and in vivo assessment of the proresolutive and antiresorptive actions of resolvin D1: relevance to arthritis

Merve Kulbay, H. Fahmi, Q. Shi, 2019, Arthritis Research & Therapy.

Bone-protective effects of nonviral gene therapy with folate-chitosan DNA nanoparticle containing interleukin-1 receptor antagonist gene in rats with adjuvant-induced arthritis.

Xiaoling Zhang, Q. Shi, J. Fernandes, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.