A. Goepferich

发表

A library of strictly linear poly(ethylene glycol)-poly(ethylene imine) diblock copolymers to perform structure-function relationship of non-viral gene carriers.

R. Rachel, M. Breunig, Sonja Bauhuber, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: disulfide bonds boost intracellular release of the cargo.

M. Breunig, A. Goepferich, Constantin Hozsa, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Mechanistic insights into linear polyethylenimine-mediated gene transfer.

T. Blunk, M. Breunig, R. Liebl, 2007, Biochimica et biophysica acta.

Gene delivery with low molecular weight linear polyethylenimines

T. Blunk, M. Breunig, R. Liebl, 2005, The journal of gene medicine.

Polymers and nanoparticles: intelligent tools for intracellular targeting?

M. Breunig, A. Goepferich, S. Bauer, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Layer-by-layer coated gold nanoparticles: size-dependent delivery of DNA into cells.

R. Rachel, T. Blunk, M. Breunig, 2012, Small.

Multivalent targeting of AT1 receptors with angiotensin II-functionalized nanoparticles

A. Goepferich, R. Hennig, K. Pollinger, 2015, Journal of drug targeting.

G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake

M. Keller, A. Buschauer, R. Rachel, 2010, Proceedings of the National Academy of Sciences.

Towards controlled release of BDNF--manufacturing strategies for protein-loaded lipid implants and biocompatibility evaluation in the brain.

T. Blunk, A. Goepferich, P. Menei, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Hydrogel wound dressings for bioactive treatment of acute and chronic wounds

Achim Goepferich, Julia Koehler, A. Goepferich, 2018 .

pH-Modulating Poly(ethylene glycol)/Alginate Hydrogel Dressings for the Treatment of Chronic Wounds.

A. Goepferich, F. Brandl, Julia Koehler, 2017, Macromolecular bioscience.

Quantum dots - nano-sized probes for the exploration of cellular and intracellular targeting.

M. Breunig, A. Goepferich, W. Hild, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Multivalent nanoparticles bind the retinal and choroidal vasculature.

E. Tamm, M. Breunig, A. Goepferich, 2015, Journal of controlled release : official journal of the Controlled Release Society.

New insights into the cross-linking and degradation mechanism of Diels-Alder hydrogels.

Hans-Joachim Wittmann, A. Strasser, A. Goepferich, 2015, Journal of materials chemistry. B.

The Effect of Ligand Mobility on the Cellular Interaction of Multivalent Nanoparticles.

A. Goepferich, S. Beck, Sara Maslanka Figueroa, 2020, Macromolecular bioscience.

Adenovirus Mimetic Nanoparticles: Sequential Ligand-Receptor Interplay as a Universal Tool for Enhanced In Vitro/In Vivo Cell Identification.

R. Witzgall, A. Goepferich, S. Beck, 2020, ACS applied materials & interfaces.

Drug release from lipid-based implants: elucidation of the underlying mass transport mechanisms.

J. Siepmann, A. Goepferich, J. Siepmann, 2006, International journal of pharmaceutics.

Polyanions effectively prevent protein conjugation and activity loss during hydrogel cross-linking.

A. Goepferich, F. Brandl, Manuel Gregoritza, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Rational design of hydrogels for tissue engineering: impact of physical factors on cell behavior.

Achim Goepferich, F. Sommer, A. Goepferich, 2007, Biomaterials.

Design of hydrogels for delayed antibody release utilizing hydrophobic association and Diels-Alder chemistry in tandem.

A. Goepferich, F. Brandl, Viktoria Messmann, 2016, Journal of materials chemistry. B.

Interaction of functionalized nanoparticles with serum proteins and its impact on colloidal stability and cargo leaching.

A. Goepferich, Sara Maslanka Figueroa, K. Abstiens, 2019, Soft matter.

Gold-Tagged Polymeric Nanoparticles with Spatially Controlled Composition for Enhanced Detectability in Biological Environments

A. Goepferich, Daniel Fleischmann, K. Abstiens, 2019, ACS Applied Nano Materials.

Synergistic effects of growth and differentiation factor-5 (GDF-5) and insulin on expanded chondrocytes in a 3-D environment.

S. Grässel, T. Blunk, A. Goepferich, 2009, Osteoarthritis and cartilage.

Biocompatibility of an injectable in situ forming depot for peptide delivery.

A. Goepferich, H. Petersen, J. Boisclair, 2010, Journal of pharmaceutical sciences.

Branched Polymer-Drug Conjugates for Multivalent Blockade of Angiotensin II Receptors.

A. Goepferich, R. Hennig, S. Kirchhof, 2015, Molecular pharmaceutics.

Nanoparticles Targeting Retinal and Choroidal Capillaries In Vivo.

A. Goepferich, Alexandra Haunberger, 2019, Methods in molecular biology.

Targeted Delivery of Soluble Guanylate Cyclase (sGC) Activator Cinaciguat to Renal Mesangial Cells via Virus-Mimetic Nanoparticles Potentiates Anti-Fibrotic Effects by cGMP-Mediated Suppression of the TGF-β Pathway

J. Schlossmann, A. Goepferich, Sara Maslanka Figueroa, 2021, International journal of molecular sciences.

In VivoDevelopment and Long-Term Survival of Engineered Adipose Tissue Depend onIn VitroPrecultivation Strategy

L. Prantl, T. Blunk, A. Seitz, 2008 .

Alkaline poly(ethylene glycol)-based hydrogels for a potential use as bioactive wound dressings.

A. Goepferich, F. Brandl, Julia Koehler, 2017, Journal of biomedical materials research. Part A.

Cleavable carbamate linkers for controlled protein delivery from hydrogels.

A. Goepferich, F. Brandl, S. Kirchhof, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Ligand Density and Linker Length are Critical Factors for Multivalent Nanoparticle-Receptor Interactions.

A. Goepferich, K. Abstiens, Manuel Gregoritza, 2018, ACS applied materials & interfaces.

Microfluidic manufacturing improves polydispersity of multicomponent polymeric nanoparticles

A. Goepferich, K. Abstiens, 2019, Journal of Drug Delivery Science and Technology.

Targeting the Central Nervous System (CNS): A Review of Rabies Virus-Targeting Strategies.

A. Goepferich, S. Geissler, Mira Oswald, 2017, Molecular pharmaceutics.

In vitro investigation of lipid implants as a controlled release system for interleukin-18.

J. Benoit, A. Goepferich, P. Menei, 2006, International journal of pharmaceutics.

Paclitaxel-loaded microparticles and implants for the treatment of brain cancer: preparation and physicochemical characterization.

J. Benoit, R. Gust, A. Goepferich, 2006, International journal of pharmaceutics.

Diels-Alder hydrogels with enhanced stability: First step toward controlled release of bevacizumab.

A. Goepferich, F. Brandl, S. Kirchhof, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Protein compatibility of selected cross-linking reactions for hydrogels.

A. Goepferich, F. Brandl, S. Kirchhof, 2015, Macromolecular bioscience.

Oligolayer-coated nanoparticles: impact of surface topography at the nanobio interface.

R. Robelek, M. Breunig, R. Liebl, 2015, ACS applied materials & interfaces.

Formation of Fenestrae in Murine Liver Sinusoids Depends on Plasmalemma Vesicle-Associated Protein and Is Required for Lipoprotein Passage

H. Kalbitzer, C. Hellerbrand, E. Tamm, 2014, PloS one.

Laser-induced graphene interdigitated electrodes for label-free or nanolabel-enhanced highly sensitive capacitive aptamer-based biosensors.

A. Baeumner, A. Goepferich, J. Min, 2020, Biosensors & bioelectronics.

Methoxy poly(ethylene glycol)--low molecular weight linear polyethylenimine-derived copolymers enable polyplex shielding.

T. Blunk, M. Breunig, R. Liebl, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Injectable in situ forming depot systems: PEG-DAE as novel solvent for improved PLGA storage stability.

A. Goepferich, H. Petersen, K. Schoenhammer, 2009, International journal of pharmaceutics.

Insulin is essential for in vitro chondrogenesis of mesenchymal progenitor cells and influences chondrogenesis in a dose-dependent manner

L. Prantl, T. Blunk, Michael B. Mueller, 2012, International Orthopaedics.

Ascorbic acid modulates proliferation and extracellular matrix accumulation of hyalocytes.

V. Gabel, F. Sommer, C. Framme, 2007, Tissue engineering.

Long time monitoring of the respiratory activity of isolated mitochondria.

O. Wolfbeis, A. Goepferich, L. Fischer, 2012, Experimental cell research.

Thermodynamic, Spatial and Methodological Considerations for the Manufacturing of Therapeutic Polymer Nanoparticles

A. Goepferich, S. Beck, Sara Maslanka Figueroa, 2020, Pharmaceutical Research.

Polyanion based controlled release system for the GnRH‐receptor antagonist degarelix

A. Goepferich, G. Schwach, Wolfgang Koechling, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

HPLC analysis as a tool for assessing targeted liposome composition.

A. Goepferich, S. Geissler, Michael Platscher, 2016, International journal of pharmaceutics.

Basic fibroblast growth factor enhances PPARgamma ligand-induced adipogenesis of mesenchymal stem cells.

M. Neubauer, T. Blunk, M. Hacker, 2004, FEBS letters.

Ocular delivery systems for poorly soluble drugs: an in-vivo evaluation.

A. Goepferich, O. Strauß, W. Herrmann, 2013, International journal of pharmaceutics.

Kidney podocytes as specific targets for cyclo(RGDfC)-modified nanoparticles.

E. Tamm, R. Witzgall, M. Breunig, 2012, Small.

Size-dependent release of fluorescent macromolecules and nanoparticles from radically cross-linked hydrogels.

A. Goepferich, J. Tessmar, F. Brandl, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Developing an in situ nanosuspension: a novel approach towards the efficient administration of poorly soluble drugs at the anterior eye.

C. Framme, A. Goepferich, J. Tessmar, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Investigation of the Diels-Alder reaction as a cross-linking mechanism for degradable poly(ethylene glycol) based hydrogels.

Achim Goepferich, A. Goepferich, F. Brandl, 2013, Journal of materials chemistry. B.

Drug Loading of Polymeric Micelles

B. Sander, A. Goepferich, Senta Uezguen, 2013, Pharmaceutical Research.

Analysis of immediate stress mechanisms upon injection of polymeric micelles and related colloidal drug carriers: implications on drug targeting.

A. Goepferich, Senta Uezguen, Tobias Miller, 2012, Biomacromolecules.

Nanoparticles Mimicking Viral Cell Recognition Strategies Are Superior Transporters into Mesangial Cells

R. Witzgall, A. Goepferich, S. Beck, 2020, Advanced science.

Nanoparticle multivalency counterbalances the ligand affinity loss upon PEGylation.

M. Breunig, A. Goepferich, R. Hennig, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Nanofibers resulting from cooperative electrostatic and hydrophobic interactions between peptides and polyelectrolytes of opposite charge.

Hans-Joachim Wittmann, A. Strasser, J. Engel, 2011, Langmuir : the ACS journal of surfaces and colloids.

Intracellular availability of poorly soluble drugs from lipid nanocapsules

A. Goepferich, Alexandra Haunberger, Marilena Bohley, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Hydrogels in ophthalmic applications.

A. Goepferich, F. Brandl, S. Kirchhof, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Controlled release of therapeutic antibody formats.

A. Goepferich, T. Serno, D. Schweizer, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Self-Assembling Colloidal System for the Ocular Administration of Cyclosporine A

A. Goepferich, J. Tessmar, O. Strauß, 2014, Cornea.

In vitro and in vivo cartilage engineering using a combination of chondrocyte-seeded long-term stable fibrin gels and polycaprolactone-based polyurethane scaffolds.

Hinrich Wiese, Achim Goepferich, Rainer Staudenmaier, 2007, Tissue engineering.

Enhanced bone morphogenetic protein-2 performance on hydroxyapatite ceramic surfaces.

A. Goepferich, J. Teßmar, H. Mayr, 2009, Journal of biomedical materials research. Part A.

Biomedical nanoparticle design: What we can learn from viruses

Sara Maslanka Figueroa, Daniel Fleischmann, Achim Goepferich, 2020, Journal of Controlled Release.

Targeting drugs to mitochondria.

G. Brockhoff, A. Goepferich, Anne Heller, 2012, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Basic fibroblast growth factor enhances PPARγ ligand‐induced adipogenesis of mesenchymal stem cells

M. Neubauer, T. Blunk, M. Hacker, 2004, FEBS letters.

A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity

E. Tamm, A. Goepferich, B. Braunger, 2022, Science advances.

Breaking up the correlation between efficacy and toxicity for nonviral gene delivery

M. Breunig, R. Liebl, A. Goepferich, 2007, Proceedings of the National Academy of Sciences.

Adipose tissue engineering based on mesenchymal stem cells and basic fibroblast growth factor in vitro.

M. Neubauer, T. Blunk, M. Hacker, 2005, Tissue engineering.

Long-term stable fibrin gels for cartilage engineering.

Hinrich Wiese, Achim Goepferich, Rainer Staudenmaier, 2007, Biomaterials.

Fluorescent Nanoparticles Coated with a Somatostatin Analogue Target Blood Monocyte for Efficient Leukaemia Treatment

A. Bouazzaoui, A. Goepferich, R. Hennig, 2020, Pharmaceutical Research.

Influence of wettability and surface activity on release behavior of hydrophilic substances from lipid matrices.

T. Blunk, A. Goepferich, J. Tessmar, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Biocompatibility and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids.

T. Blunk, M. Hacker, A. Goepferich, 2006, International journal of pharmaceutics.

Fabrication of antibody‐loaded microgels using microfluidics and thiol‐ene photoclick chemistry

A. Goepferich, K. Abstiens, Manuel Gregoritza, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Programmable implants--from pulsatile to controlled release.

J. Siepmann, T. Blunk, A. Goepferich, 2006, International journal of pharmaceutics.

Diels-Alder Hydrogels for Controlled Antibody Release: Correlation between Mesh Size and Release Rate.

A. Goepferich, F. Brandl, M. Grassi, 2015, Molecular pharmaceutics.

Angiopoietin-1 Mimetic Nanoparticles for Restoring the Function of Endothelial Cells as Potential Therapeutic for Glaucoma

E. Tamm, M. Breunig, A. Goepferich, 2021, Pharmaceuticals.

Nanoparticles for the treatment of ocular neovascularizations.

A. Goepferich, R. Hennig, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

In Situ Forming iEDDA Hydrogels with Tunable Gelation Time Release High-Molecular Weight Proteins in a Controlled Manner over an Extended Time.

M. Nagaoka, A. Goepferich, Moritz Graf, 2021, Biomacromolecules.

Biodistribution of quantum dots in the kidney after intravenous injection.

A. Buschauer, R. Witzgall, M. Breunig, 2014, Journal of nanoscience and nanotechnology.

Determination of the activity of maleimide-functionalized phospholipids during preparation of liposomes.

A. Goepferich, S. Geissler, Mira Oswald, 2016, International journal of pharmaceutics.

Design of dye and superparamagnetic iron oxide nanoparticle loaded lipid nanocapsules with dual detectability in vitro and in vivo.

E. Tamm, A. Goepferich, A. Dillinger, 2020, International journal of pharmaceutics.

Premature drug release of polymeric micelles and its effects on tumor targeting.

U. Haberkorn, A. Goepferich, W. Mier, 2013, International journal of pharmaceutics.

Comparative Investigations on In Vitro Serum Stability of Polymeric Micelle Formulations

R. Rachel, Ahmed Besheer, A. Goepferich, 2012, Pharmaceutical Research.

In vivo development and long-term survival of engineered adipose tissue depend on in vitro precultivation strategy.

Achim Goepferich, Lukas Prantl, Claudia Fischbach-Teschl, 2008, Tissue engineering. Part A.

Cell-delivery therapeutics for adipose tissue regeneration.

T. Blunk, A. Goepferich, P. Bauer-Kreisel, 2010, Advanced drug delivery reviews.

Pharmacokinetics, biocompatibility and bioavailability of a controlled release monoclonal antibody formulation.

H. Gram, A. Goepferich, M. Jahn, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Synthesis and in vitro hydroxyapatite binding of peptides conjugated to calcium-binding moieties.

A. Mikos, J. Hartgerink, A. Goepferich, 2007, Biomacromolecules.

Layer-by-layer assembled gold nanoparticles for siRNA delivery.

Achim Goepferich, Reinhard Rachel, Miriam Breunig, 2009, Nano letters.

Biodegradable hydrogels for time-controlled release of tethered peptides or proteins.

T. Blunk, A. Goepferich, J. Tessmar, 2010, Biomacromolecules.

Fluorescence resonance energy transfer: evaluation of the intracellular stability of polyplexes.

M. Breunig, R. Liebl, A. Goepferich, 2006, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Influenza A virus mimetic nanoparticles trigger selective cell uptake

A. Goepferich, S. Beck, Sara Maslanka Figueroa, 2019, Proceedings of the National Academy of Sciences.

RNA "traffic lights": an analytical tool to monitor siRNA integrity.

M. Breunig, R. Liebl, A. Goepferich, 2013, ACS chemical biology.

An Approach to Classify Degradable Polymers

A. Goepferich, F. V. Burkersroda, 1998 .

Hydrogel microspheres evading alveolar macrophages for sustained pulmonary protein delivery.

A. Goepferich, Manuel Gregoritza, Moritz Graf, 2019, International journal of pharmaceutics.

Drug Loading of Polymeric Micelles

B. Sander, A. Goepferich, Senta Uezguen, 2013, Pharmaceutical Research.

Ligand-functionalized nanoparticles target endothelial cells in retinal capillaries after systemic application

E. Tamm, M. Breunig, A. Goepferich, 2013, Proceedings of the National Academy of Sciences.

The mechanism of protein release from triglyceride microspheres.

M. Breunig, A. Goepferich, A. Elbakry, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Bone Morphogenetic Protein 9: A Potent Modulator of Cartilage Development In Vitro

T. Blunk, A. Goepferich, A. L. Sieminski, 2003, Growth factors.

Poly(ethyleneglycol) 500 Dimethylether as Novel Solvent for Injectable In Situ Forming Depots

A. Goepferich, H. Petersen, K. Schoenhammer, 2009, Pharmaceutical Research.

Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells

F. Sommer, M. Neubauer, T. Blunk, 2008, Cells Tissues Organs.

Injectable Anhydrous Poly(ethylene glycol) Polymer Liquids Form Protein Depot for Extended Controlled Release Applications Via Rapid In Situ Gelation.

M. Nagaoka, M. Breunig, A. Goepferich, 2023, Molecular pharmaceutics.

Controlled Antibody Release from Degradable Thermoresponsive Hydrogels Cross-Linked by Diels-Alder Chemistry.

A. Goepferich, F. Brandl, Viktoria Messmann, 2017, Biomacromolecules.

Polyplexes of polyethylenimine and per-N-methylated polyethylenimine-cytotoxicity and transfection efficiency.

T. Blunk, M. Breunig, A. Goepferich, 2004, Journal of nanoscience and nanotechnology.

The impact of polyelectrolyte structure on the shape of nanoassemblies with cationic peptides.

J. Engel, R. Rachel, A. Goepferich, 2013, Journal of pharmaceutical sciences.

Cyclic RGD peptides target human trabecular meshwork cells while ameliorating connective tissue growth factor-induced fibrosis

A. Goepferich, R. Hennig, R. Fuchshofer, 2016, Journal of drug targeting.

Encapsulation of Pioglitazone into Polymer-Nanoparticles for Potential Treatment of Atherosclerotic Diseases.

M. Breunig, A. Goepferich, Daniel Fleischmann, 2023, ACS applied bio materials.

G protein-coupled receptors function as logic gates for nanoparticle binding and cell uptake

M. Keller, A. Buschauer, R. Rachel, 2010, Proceedings of the National Academy of Sciences.

Multivalent targeting of AT1 receptors with angiotensin II-functionalized nanoparticles

A. Goepferich, R. Hennig, K. Pollinger, 2015, Journal of drug targeting.

Controlled Antibody Release from Degradable Thermoresponsive Hydrogels Cross-Linked by Diels-Alder Chemistry.

A. Goepferich, F. Brandl, Viktoria Messmann, 2017, Biomacromolecules.

A novel anhydrous preparation of PEG hydrogels enables high drug loading with biologics for controlled release applications

A. Goepferich, S. Beck, Moritz Graf, 2021 .

New insights into the cross-linking and degradation mechanism of Diels-Alder hydrogels.

Hans-Joachim Wittmann, A. Strasser, A. Goepferich, 2015, Journal of materials chemistry. B.

Impact of interferon-γ on the target cell tropism of nanoparticles.

R. Witzgall, A. Goepferich, Oliver Zimmer, 2023, Journal of controlled release : official journal of the Controlled Release Society.

How clathrin-coated pits control nanoparticle avidity for cells.

A. Goepferich, Oliver Zimmer, 2023, Nanoscale horizons.