J. Bertrand

发表

Influence of the Internalization Pathway on the Efficacy of siRNA Delivery by Cationic Fluorescent Nanodiamonds in the Ewing Sarcoma Cell Model

Géraldine Dantelle, François Treussart, E. Le Cam, 2012, PloS one.

Optimisation of dendrimer‐mediated gene transfer by anionic oligomers

M. Gottikh, J. Majoral, C. Malvy, 2003, The journal of gene medicine.

Nanodiamond as a vector for siRNA delivery to Ewing sarcoma cells.

Thierry Gacoin, Marie-Pierre Adam, Géraldine Dantelle, 2011, Small.

The Solution Synthesis of Antisense Oligonucleotide‐Peptide Conjugates Directly Linked via Phosphoramide Bond by Using a Fragment Coupling Approach

M. Gottikh, C. Malvy, J. Bertrand, 2004, Nucleosides, nucleotides & nucleic acids.

Microscopic observation of living cells during their exposure to modulated electromagnetic fields.

L. Mir, P. Leveque, J. Bertrand, 2008, Bioelectrochemistry.

Plasma hydrogenated cationic detonation nanodiamonds efficiently deliver to human cells in culture functional siRNA targeting the Ewing sarcoma junction oncogene.

François Treussart, Tristan Petit, Jean-Charles Arnault, 2015, Biomaterials.

Delivery of siRNA to Ewing Sarcoma Tumor Xenografted on Mice, Using Hydrogenated Detonation Nanodiamonds: Treatment Efficacy and Tissue Distribution

H. Girard, J. Arnault, F. Treussart, 2020, Nanomaterials.

Delivery of siRNA to Ewing Sarcoma Tumor Xenografted on Mice, Using Hydrogenated Detonation Nanodiamonds: Treatment Efficacy and Tissue Distribution

H. Girard, J. Arnault, F. Treussart, 2020, Nanomaterials.

Fluorescent Nanodiamond Applications for Cellular Process Sensing and Cell Tracking

F. Treussart, J. Bertrand, S. Claveau, 2018, Micromachines.

Sequence-specific interaction of α β-anomeric doublestranded DNA with the p50 subunit of NFxB: application to the decoy approach

C. Malvy, J. Bertrand, B. Rayner, 1994 .

Cellular uptake pathways of sepiolite nanofibers and DNA transfection improvement

E. Le Cam, P. Aranda, E. Ruiz-Hitzky, 2017, Scientific Reports.

Gymnotic delivery and gene silencing activity of reduction-responsive siRNAs bearing lipophilic disulfide-containing modifications at 2'-position.

J. Bertrand, J. Vasseur, F. Debart, 2018, Bioorganic & medicinal chemistry.

Comparative activity of α- and β-anomeric oligonucleotides on rabbit β globin synthesis: Inhibitory effect of cap targeted α-oligonucleotides

C. Paoletti, C. Malvy, J. Bertrand, 1989 .

Synthesis, binding, nuclease resistance and cellular uptake properties of 2'-O-acetalester-modified oligonucleotides containing cationic groups.

J. Bertrand, J. Vasseur, F. Debart, 2015, Bioorganic & medicinal chemistry.

Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers

J. Bertrand, J. Vasseur, F. Debart, 2020, Molecules.

siRNA nanoformulation against the Ret/PTC1 junction oncogene is efficient in an in vivo model of papillary thyroid carcinoma

P. Couvreur, M. Santoro, A. Fusco, 2007, Nucleic acids research.

Formation of stable triplexes between purine RNA and pyrimidine oligodeoxyxylonucleotides.

M. Gottikh, C. Malvy, J. Bertrand, 2003, Nucleic acids research.

Lipophilic 2′‐O‐Acetal Ester RNAs: Synthesis, Thermal Duplex Stability, Nuclease Resistance, Cellular Uptake, and siRNA Activity after Spontaneous Naked Delivery

G. Sczakiel, J. Bertrand, J. Vasseur, 2016, Chembiochem : a European journal of chemical biology.

New Core-Shell Nanoparticules for the Intravenous Delivery of siRNA to Experimental Thyroid Papillary Carcinoma

P. Couvreur, C. Malvy, J. Bertrand, 2010, Pharmaceutical Research.

9-Aminoellipticine-Derivatized α- and β-Oligodeoxyribonucleotides Targeted to the Cap of β-Globin mRNA: Hybridization to Natural and Engineered mRNA, Inhibition of Translation, and Improved Effect of Tandem Chains

C. Malvy, J. Bertrand, B. Rayner, 1992 .

Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells

E. Le Cam, P. Aranda, E. Ruiz-Hitzky, 2016, Scientific Reports.

A base-labile group for 2'-OH protection of ribonucleosides: a major challenge for RNA synthesis.

Thomas Lavergne, Jean-Jacques Vasseur, T. Lavergne, 2008, Chemistry.

Inhibition of moloney murine leukemia virus reverse transcriptase by α-anomeric oligonucleotides

C. Paoletti, C. Malvy, J. Bertrand, 1989 .

α-Anomeric DNA: β-RNA hybrids as new synthetic inhibitors of Escherichia coli RNase H, Drosophila embryo RNase H and M-MLV reverse transcriptase

F. Pognan, C. Paoletti, C. Malvy, 1988 .

In vitro inhibition of the pim-1 protooncogene by chimeric oligodeoxyribonucleotides composed of a- and β-anomeric fragments

F. Dautry, C. Malvy, J. Bertrand, 1994 .

Alpha beta chimeric antisense oligonucleotides: synthesis and nuclease resistance in biological media.

C. Malvy, J. Bertrand, E. Lescot, 1994, Antisense research and development.

α−β Chimeric Oligonucleotides Form a New Stable “Snail-like” Structure

O. Fedorova, C. Malvy, J. Bertrand, 1996 .

Apurinic DNA: Modelisation and Reactivity Towards 9-Aminoellipticine and Related Amines

C. Paoletti, C. Malvy, J. Bertrand, 1989 .

Efficacy of siRNA Nanocapsules Targeted Against the EWS–Fli1 Oncogene in Ewing Sarcoma

P. Couvreur, A. Tamaddon, C. Malvy, 2006, Pharmaceutical Research.

Delivery of Small Interfering RNA. A Review and an Example of Application to a Junction Oncogene

C. Malvy, J. Bertrand, A. Ramon, 2008, Tumori.

Intravenous delivery of anti-RhoA small interfering RNA loaded in nanoparticles of chitosan in mice: safety and efficacy in xenografted aggressive breast cancer.

P. Opolon, J. Soria, C. Soria, 2006, Human gene therapy.

Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo.

P. Opolon, A. Vekris, C. Malvy, 2002, Biochemical and biophysical research communications.

Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

P. Opolon, Hong Li, J. Soria, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

Comparative Activity and Specificity of Antisense Oligodeoxynucleotides and Small Interfering RNA in an in vitro Ewing Sarcoma Model

A. Tamaddon, C. Malvy, J. Bertrand, 2009 .

Intravenous delivery of anti-RhoA siRNA loaded in nanoparticles of chitosan in mice: safety and efficacy in xenografted breast cancer.

P. Opolon, Hong Li, J. Soria, 2006 .

Preactivated oxazaphosphorines designed for isophosphoramide mustard delivery as bulk form or nanoassemblies: synthesis and proof of concept.

A. Paci, G. Vassal, P. Couvreur, 2015, Journal of medicinal chemistry.

Harnessing subcellular-resolved organ distribution of cationic copolymer-functionalized fluorescent nanodiamonds for optimal delivery of active siRNA to a xenografted tumor in mice.

P. Georges, R. López-Alemany, P. Cígler, 2020, Nanoscale.

Therapeutic Potentialities of EWS‐Fli‐1 mRNA‐Targeted Vectorized Antisense Oligonucleotides

P. Couvreur, C. Malvy, J. Bertrand, 2003, Annals of the New York Academy of Sciences.

Antitumor vectorized oligonucleotides in a model of ewing sarcoma: unexpected role of nanoparticles.

C. Malvy, J. Bertrand, A. Maksimenko, 2009, Oligonucleotides.

Synthesis and studies on cell-penetrating peptides.

C. Malvy, J. Bertrand, I. Laczkó, 2009, Bioconjugate chemistry.

Turning Squalene into Cationic Lipid Allows a Delivery of siRNA in Cultured Cells.

P. Couvreur, Catherine Durieu, C. Malvy, 2015, Nucleic acid therapeutics.

Effects of siRNA on RET/PTC3 Junction Oncogene in Papillary Thyroid Carcinoma: From Molecular and Cellular Studies to Preclinical Investigations

P. Couvreur, J. Bertrand, L. Massaad-Massade, 2014, PloS one.

In Vivo Potentialities of EWS‐Fli‐1 Targeted Antisense Oligonucleotides‐Nanospheres Complexes

P. Couvreur, C. Malvy, J. Bertrand, 2005, Annals of the New York Academy of Sciences.

EWS fli-1 antisense nanocapsules inhibits ewing sarcoma-related tumor in mice.

P. Couvreur, C. Malvy, J. Bertrand, 2000, Biochemical and biophysical research communications.

NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS

M. Gottikh, C. Malvy, J. Bertrand, 2004 .

Differential reactivity of 9‐NH2‐ellipticine on apurinic and apyrimidinic sites in circular DNA

C. Malvy, J. Bertrand, J. Bertrand, 1986, FEBS letters.

Simultaneous cathodoluminescence and electron microscopy cytometry of cellular vesicles labeled with fluorescent nanodiamonds.

E. Le Cam, F. Treussart, J. Bertrand, 2016, Nanoscale.

Antisense oligonucleotide nanocapsules efficiently inhibit EWS-Fli1 expression in a Ewing's sarcoma model.

P. Couvreur, C. Malvy, J. Bertrand, 2006, Oligonucleotides.