P. Vader

发表

Optimization of poly(amido amine)s as vectors for siRNA delivery.

J. Engbersen, R. Schiffelers, G. Storm, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Extracellular Vesicles and Their Emerging Roles as Cellular Messengers in Endocrinology: An Endocrine Society Scientific Statement.

Alissa M. Weaver, G. Rice, R. Kalluri, 2022, Endocrine reviews.

Cells release subpopulations of exosomes with distinct molecular and biological properties

Henrik J Johansson, Janne Lehtiö, Imre Mäger, 2016, Scientific Reports.

Injectable Supramolecular Ureidopyrimidinone Hydrogels Provide Sustained Release of Extracellular Vesicle Therapeutics

M. Goumans, P. Doevendans, J. Sluijter, 2019, Advanced healthcare materials.

Drug Delivery with Extracellular Vesicles: From Imagination to Innovation

J. Sluijter, R. Schiffelers, P. Vader, 2019, Accounts of chemical research.

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

Imre Mäger, Pieter Vader, Ylva Gustafsson, 2015, Journal of extracellular vesicles.

Extracellular Vesicle Heterogeneity: Subpopulations, Isolation Techniques, and Diverse Functions in Cancer Progression

Imre Mäger, Pieter Vader, Matthew J. A. Wood, 2018, Front. Immunol..

State-of-the-Art Design and Rapid-Mixing Production Techniques of Lipid Nanoparticles for Nucleic Acid Delivery

R. Schiffelers, P. Cullis, P. Vader, 2018 .

Influence of short term storage conditions, concentration methodsand excipients on extracellular vesicle recovery and function.

J. Sluijter, S. El Andaloussi, P. Vader, 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Profiling of Extracellular Small RNAs Highlights a Strong Bias towards Non-Vesicular Secretion

K. Krjutškov, R. Vandenbroucke, J. Westholm, 2020, bioRxiv.

Challenges and directions in studying cell–cell communication by extracellular vesicles

A. Clayton, G. Raposo, P. Vader, 2022, Nature Reviews Molecular Cell Biology.

Elevated levels of squamous cell carcinoma antigen in patients with a benign disease of the skin

H. Hollema, H. D. de Bruijn, P. Vader, 1989, Cancer.

Delivery of modified mRNA to damaged myocardium by systemic administration of lipid nanoparticles.

R. Schiffelers, E. Mastrobattista, M. V. van Steenbergen, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Approaches to surface engineering of extracellular vesicles.

P. Vader, G. Fuhrmann, Maximilian Richter, 2021, Advanced drug delivery reviews.

Cetuximab treatment alters the content of extracellular vesicles released from tumor cells.

R. Schiffelers, P. Vader, R. van der Meel, 2016, Nanomedicine.

Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

Pieter Vader, Raymond M. Schiffelers, R. Schiffelers, 2016, Journal of extracellular vesicles.

Extracellular Vesicle-Based Hybrid Systems for Advanced Drug Delivery

P. Vader, D. A. Rodríguez, 2022, Pharmaceutics.

Cellular uptake of extracellular vesicles is mediated by clathrin‐independent endocytosis and macropinocytosis

R. Schiffelers, P. Vader, Helena Costa Verdera, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Identification of storage conditions stabilizing extracellular vesicles preparations

Antje M Zickler, S. El Andaloussi, P. Vader, 2022, Journal of extracellular vesicles.

Tumour-bound RNA-laden exosomes

R. Schiffelers, P. Vader, S. Kooijmans, 2017, Nature Biomedical Engineering.

follow-up . reaction and cell culture for diagnosis and population : comparison of polymerase chain Chlamydia trachomatis infection in a high-risk

P. Vader, W. Vogels, F. P. Schröder, 2003 .

Natural or Synthetic RNA Delivery: A Stoichiometric Comparison of Extracellular Vesicles and Synthetic Nanoparticles

R. Schiffelers, P. Vader, Olivier G. de Jong, 2021, Nano letters.

MN11 C9ORF72 and RAB7L1 regulate vesicle traffi cking in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

M. Turner, K. Talbot, R. Manzano, 2017, Neuromuscular Disorders.

Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine

J. Sluijter, R. Schiffelers, P. Vader, 2019, Cells.

Primary and secondary cutaneous CD30+lymphoproliferative disorders: a report from the Dutch Cutaneous Lymphoma Group on the long-term follow-up data of 219 patients and guidelines for diagnosis and treatment

C. Meijer, W. Vloten, P. Vader, 2000 .

SYPHILIS MANAGEMENT AND TREATMENT

P. Vader, 1998 .

Taxol(®)-induced phosphatidylserine exposure and microvesicle formation in red blood cells is mediated by its vehicle Cremophor(®) EL.

A. Egberts, R. Schiffelers, N. Sachini, 2013, Nanomedicine.

Normoxic Tumour Extracellular Vesicles Modulate the Response of Hypoxic Cancer and Stromal Cells to Doxorubicin In Vitro

R. Schiffelers, P. Vader, M. Fens, 2020, International journal of molecular sciences.

Applying extracellular vesicles based therapeutics in clinical trials (cid:2) an ISEV position paper

L. O’Driscoll, D. Strunk, J. Lötvall, 2015 .

Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper

Andrew F. Hill, Bernd Giebel, André Görgens, 2015, Journal of extracellular vesicles.

Interfering with endolysosomal trafficking enhances release of bioactive exosomes.

J. Sluijter, R. Schiffelers, P. Vader, 2019, Nanomedicine : nanotechnology, biology, and medicine.

Physicochemical and Biological Evaluation of siRNA Polyplexes Based on PEGylated Poly(amido amine)s

J. Engbersen, R. Schiffelers, G. Storm, 2011, Pharmaceutical Research.

A post-insertion strategy for surface functionalization of bacterial and mammalian cell-derived extracellular vesicles.

W. Hennink, R. Schiffelers, P. Vader, 2020, Biochimica et biophysica acta. General subjects.

Extracellular vesicles for drug delivery.

Pieter Vader, Emma A Mol, Gerard Pasterkamp, 2016, Advanced drug delivery reviews.

ISOLATION METHODS OF LARGE AND SMALL EXTRACELLULAR VESICLES DERIVED FROM CARDIOVASCULAR PROGENITORS: A COMPARATIVE STUDY.

P. Vader, E. Garbayo, M. Blanco-Prieto, 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

RAPID DETECTION WITH MONOCLONAL ANTIBODIES OF CHLAMYDIA TRACHOMATIS IN URETHRAL SMEARS AND URINE SEDIMENTS

P. Vader, G. Ruijs, J. Schirm, 1984, The Lancet.

Interaction of Extracellular Vesicles with Endothelial Cells Under Physiological Flow Conditions.

R. Schiffelers, P. Vader, O. Eniola-Adefeso, 2017, Methods in molecular biology.

Evaluation and manipulation of tissue and cellular distribution of cardiac progenitor cell-derived extracellular vesicles

J. Sluijter, M. Brans, P. Vader, 2022, Frontiers in Pharmacology.

4 Is surveillance effective, and who should be under surveillance? Results of a national surveillance program for familial melanoma

N. Gruis, W. Bergman, H. Vasen, 2013 .

Extracellular vesicles as drug delivery systems: Why and how?

R. Schiffelers, J. Nordin, P. Vader, 2020, Advanced drug delivery reviews.

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Jing Xu, Antonella Bongiovanni, Wilfrid Boireau, 2018, Journal of Extracellular Vesicles.

Hydrogel‐Induced Cell Membrane Disruptions Enable Direct Cytosolic Delivery of Membrane‐Impermeable Cargo

C. Vanhove, K. Braeckmans, S. D. De Smedt, 2021, Advanced materials.

Primary and secondary cutaneous CD 30 1 lymphoproliferative disorders : a report from the Dutch Cutaneous Lymphoma Group on the long-term follow-up data of 219 patients and guidelines for diagnosis and treatment

C. Meijer, W. Vloten, P. Vader, 2022 .

Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering

K. Braeckmans, E. Mastrobattista, S. D. De Smedt, 2021, Molecular therapy. Nucleic acids.

Physicochemical and Biological Evaluation of siRNA Polyplexes Based on PEGylated Poly(amido amine)s

J. Engbersen, R. Schiffelers, G. Storm, 2011, Pharmaceutical Research.

Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop

S. Bhattacharyya, R. Vandenbroucke, M. Wauben, 2019, Journal of extracellular vesicles.

MISEV 2018 ) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV 2014 guidelines

Krisztina V. Vukman, Scott M Langevin, Valentina R Minciacchi, 2018 .

Challenges and directions in studying cell–cell communication by extracellular vesicles

A. Clayton, G. Raposo, P. Vader, 2022, Nature Reviews Molecular Cell Biology.

Illuminating RNA trafficking and functional delivery by extracellular vesicles.

P. Vader, M. Tanenbaum, Willemijn S de Voogt, 2021, Advanced drug delivery reviews.

Recombinant phosphatidylserine-binding nanobodies for targeting of extracellular vesicles to tumor cells: a plug-and-play approach† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7nr06966a

R. Schiffelers, P. Vader, S. Kooijmans, 2018, Nanoscale.

Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking

R. Schiffelers, M. Wood, P. Vader, 2019, Experimental & Molecular Medicine.

Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes

R. Schiffelers, B. W. van Balkom, Yong Chen, 2012, Journal of extracellular vesicles.

Hepatologic Side Effects during Long-Term Retinoid Therapy: Ito Cells and Portal Hypertension

H. Verweij, C. Gips, P. Vader, 1985 .

Exosome mimetics: a novel class of drug delivery systems

R. Schiffelers, P. Vader, W. V. van Solinge, 2012, International journal of nanomedicine.

Functional siRNA Delivery by Extracellular Vesicle–Liposome Hybrid Nanoparticles

J. Sluijter, R. Schiffelers, P. Vader, 2021, Advanced healthcare materials.

A call for the standardised reporting of factors affecting the exogenous loading of extracellular vesicles with therapeutic cargos

L. O’Driscoll, P. Vader, B. Giebel, 2021, Advanced drug delivery reviews.

Extracellular Vesicle-Associated Proteins in Tissue Repair.

J. Sluijter, P. Vader, M. Roefs, 2020, Trends in cell biology.

A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA

R. Schiffelers, J. van Rheenen, M. Wood, 2020, Nature Communications.

Higher functionality of extracellular vesicles isolated using size-exclusion chromatography compared to ultracentrifugation.

M. Goumans, P. Doevendans, J. Sluijter, 2017, Nanomedicine : nanotechnology, biology, and medicine.

Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles

Jinghuan Li, Janne Lehtiö, Imre Mäger, 2015, Journal of extracellular vesicles.

Examining the role of Rac1 in tumor angiogenesis and growth: a clinically relevant RNAi-mediated approach

R. Schiffelers, M. Symons, G. Storm, 2011, Angiogenesis.

Disulfide-Based Poly(amido amine)s for siRNA Delivery: Effects of Structure on siRNA Complexation, Cellular Uptake, Gene Silencing and Toxicity

J. Engbersen, R. Schiffelers, G. Storm, 2010, Pharmaceutical Research.

TOP-EV: Technology of protein loading through Extracellular Vesicle is a versatile platform for intracellular protein delivery.

J. Sluijter, R. Schiffelers, A. Gunnarsson, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Microvesicles and exosomes: opportunities for cell-derived membrane vesicles in drug delivery.

R. Schiffelers, M. Wood, P. Vader, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Extracellular vesicles: emerging targets for cancer therapy.

Pieter Vader, X. Breakefield, M. Wood, 2014, Trends in molecular medicine.

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency

R. Schiffelers, M. Wood, M. Pooga, 2016, Molecular Therapy: Nucleic Acids.

IUSTI/WHO Europe Workshop on Management of Syphilis: 6 scientific background papers 1

P. Vader, 2004 .

Functional Delivery of Lipid-Conjugated siRNA by Extracellular Vesicles.

R. Schiffelers, M. Wood, I. Mäger, 2017, Molecular therapy : the journal of the American Society of Gene Therapy.

HIGHER MAST CELL LOAD LOWERS RISK OF HYMENOPTERA VENOM ANAPHYLAXIS IN MASTOCYTOSIS

P. Vader, J. Kluin-Nelemans, J. G. Monchy, 2019 .

Extracellular vesicle-based therapeutics: natural versus engineered targeting and trafficking

R. Schiffelers, M. Wood, P. Vader, 2019, Experimental & Molecular Medicine.

Ischaemia alters the effects of cardiomyocyte‐derived extracellular vesicles on macrophage activation

Teresa M. Ribeiro-Rodrigues, M. Cruz, P. Vader, 2018, Journal of cellular and molecular medicine.

Albinistic common seals ( Phoca vitulina ) and melanistic grey seals ( Halichoerus grypus ) rehabilitated in the Netherlands

P. Vader, N. Osinga, P. Hart, 2010 .

PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time.

R. Schiffelers, P. Vader, M. Fens, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Extracellular vesicles as drug delivery systems: lessons from the liposome field.

Pieter Vader, Raymond M Schiffelers, Omolola Eniola-Adefeso, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties.

Henrik J Johansson, Janne Lehtiö, Imre Mäger, 2015, Nanomedicine : nanotechnology, biology, and medicine.

Probing the membrane interface-interacting proteome using photoactivatable lipid cross-linkers.

M. Slijper, B. de Kruijff, P. Vader, 2007, Journal of proteome research.

Extracellular microRNAs are dynamic non-vesicular biomarkers of muscle turnover

I. Sargent, M. Wood, Y. Aoki, 2013, Nucleic acids research.

Electroporation-induced siRNA precipitation obscures the efficiency of siRNA loading into extracellular vesicles.

K. Braeckmans, A. Hendrix, R. Schiffelers, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Targeted delivery of small interfering RNA to angiogenic endothelial cells with liposome-polycation-DNA particles.

R. Schiffelers, G. Storm, P. Vader, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Syphilis management and treatment : Sexually transmitted diseases

P. Vader, 1998 .

Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy

R. Schiffelers, P. Vader, L. Jiang, 2017, Gene Therapy.

Preparation and Isolation of siRNA-Loaded Extracellular Vesicles.

Imre Mäger, Pieter Vader, M. Wood, 2017, Methods in molecular biology.

New considerations in the preparation of nucleic acid-loaded extracellular vesicles.

P. Vader, K. Raemdonck, S. Stremersch, 2014, Therapeutic delivery.

A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA

R. Schiffelers, J. van Rheenen, M. Wood, 2020, Nature Communications.

Cardiac Progenitor Cell–Derived Extracellular Vesicles Reduce Infarct Size and Associate with Increased Cardiovascular Cell Proliferation

M. Goumans, J. Sluijter, P. Vader, 2018, Journal of Cardiovascular Translational Research.

Tumour-bound RNA-laden exosomes

R. Schiffelers, P. Vader, S. Kooijmans, 2017, Nature Biomedical Engineering.

Microbubbles-Assisted Ultrasound Triggers the Release of Extracellular Vesicles

C. Moonen, R. Deckers, C. Bos, 2017, International journal of molecular sciences.

Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery

R. Vandenbroucke, I. Mäger, T. Roberts, 2023, bioRxiv.

Extracellular Vesicle Heterogeneity and Its Impact for Regenerative Medicine Applications

P. Vader, S. I. van de Wakker, F. M. Meijers, 2023, Pharmacological Reviews.

Multimodal engineering of extracellular vesicles for efficient intracellular protein delivery

R. Vandenbroucke, I. Mäger, T. Roberts, 2024, bioRxiv.

A method for quantifying cellular uptake of fluorescently labeled siRNA.

J. Engbersen, R. Schiffelers, G. Storm, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Lack of involvement of CD63 and CD9 tetraspanins in the extracellular vesicle content delivery process

P. Vader, E. Rubinstein, Olivier G. de Jong, 2023, Communications biology.

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles.

M. Mayr, P. Menasché, E. Buzás, 2022, Cardiovascular research.

Delivery systems for siRNA : towards targeted inhibition of tumor angiogenesis

P. Vader, 2012 .

Heparin interferes with the uptake of liposomes in glioma

R. Schiffelers, P. Vader, K. O’Brien, 2023, International journal of pharmaceutics: X.

Polymeric carrier systems for siRNA delivery.

J. Engbersen, R. Schiffelers, G. Storm, 2012, Current Topics in Medicinal Chemistry.

Intercalating quaternary nicotinamide-based poly(amido amine)s for gene delivery.

R. Schiffelers, G. Storm, L. J. van der Aa, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Poly(amido amine) copolymers derived from aminobutanol and ethylene diamine are excellent carriers for siRNA delivery.

J. Engbersen, R. Schiffelers, L. J. van der Aa, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Extracellular vesicle‐mediated protein delivery to the liver

M. Brans, R. Schiffelers, P. Vader, 2023, Journal of extracellular biology.

High risk groups in cutaneous oncology: basal cell nevus syndrome, xeroderma pigmentosum and epidermodysplasia verruciformis

P. Vader, 1986 .

Extracellular vesicles as drug delivery systems: lessons from the liposome field.

R. Schiffelers, P. Vader, O. Eniola-Adefeso, 2014, Journal of controlled release : official journal of the Controlled Release Society.

[The rise in fluoroquinolone-resistant Neisseria gonorrhoeae among people attending the Municipal Health Service's clinic for sexually transmitted diseases in Amsterdam, the Netherlands; cefotaxime now first-choice treatment for uncomplicated gonorrhoea].

P. Vader, J. Fennema, J. V. Bergen, 2004, Nederlands tijdschrift voor geneeskunde.