S. Dilly

发表

The sigma agonist 1,3-di-o-tolyl-guanidine directly blocks SK channels in dopaminergic neurons and in cell lines.

J. Scuvée-Moreau, Cédric Lamy, S. Dilly, 2010, European journal of pharmacology.

Distinction between 2′- and 3′-Phosphate Isomers of a Fluorescent NADPH Analogue Led to Strong Inhibition of Cancer Cells Migration

A. Escargueil, P. Abbe, J. Boucher, 2021, Antioxidants.

Bis‐(1,2,3,4‐tetrahydroisoquinolinium): A Chiral Scaffold for Developing High‐Affinity Ligands for SK Channels

J. Wouters, S. Dilly, J. Liégeois, 2014, ChemMedChem.

Synthesis and radioligand binding studies of bis-(8-isopropyl-isoquinolinium) derivatives as ligands for apamin-sensitive sites on cloned SK2 and SK3 channels.

S. Dilly, J. Liégeois, V. Seutin, 2011, Bioorganic & medicinal chemistry letters.

Lung deposition and pharmacokinetics of nebulized cyclosporine in lung transplant patients.

T. Corcoran, S. Dilly, R. Niven, 2014, Journal of aerosol medicine and pulmonary drug delivery.

Enhancing a CH-π Interaction to Increase the Affinity for 5-HT1A Receptors.

J. Scuvée-Moreau, S. Dilly, J. Liégeois, 2014, ACS medicinal chemistry letters.

Three-Dimensional Quantitative Structure–Activity Relationship of MT3 Melatonin Binding Site Ligands: A Comparative Molecular Field Analysis

J. Boutin, P. Renard, P. Chavatte, 2007 .

Antioxydant activity of β-carboline derivatives in the LDL oxidation model.

P. Chavatte, S. Dilly, S. Yous, 2011, European journal of medicinal chemistry.

New pyridobenzoxazepine derivatives derived from 5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5]benzoxazepine (JL13): chemical synthesis and pharmacological evaluation.

F. Tarazi, Cédric Lamy, S. Dilly, 2012, Journal of medicinal chemistry.

Neuropeptides, New Ligands of SARS-CoV-2 Nucleoprotein, a Potential Link between Replication, Inflammation and Neurotransmission

C. Di Primo, S. Dilly, Anny Slama Schwok, 2022, Molecules.

New substituted aryl esters and aryl amides of 3,4-dihydro-2H-1,2,4- benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors

L. Danober, P. Tullio, P. Lestage, 2011 .

Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds.

J. Kastrup, S. Dilly, B. Pirotte, 2018, Journal of medicinal chemistry.

Identification and pharmacological characterization of succinate receptor agonists

F. Jouret, A. Inoue, S. Dilly, 2017, British journal of pharmacology.

Bis-tetrahydroisoquinoline derivatives: AG525E1, a new step in the search for non-quaternary non-peptidic small conductance Ca(2+)-activated K(+) channel blockers.

J. Wouters, P. Chavatte, Cédric Lamy, 2008, Bioorganic & medicinal chemistry letters.

Structural analysis of some bis-(8-isopropyl-isoquinolinium) derivatives reveals a preferential folded conformation leading to a stereoselective attack by sodium borohydride

J. Wouters, P. Hubert, S. Dilly, 2014 .

Quantitative structure-activity relationships studies of antioxidant hexahydropyridoindoles and flavonoid derivatives

P. Chavatte, A. Farce, S. Dilly, 2007, Journal of enzyme inhibition and medicinal chemistry.

From Naproxen Repurposing to Naproxen Analogues and Their Antiviral Activity against Influenza A Virus.

M. Alessi, J. Vidić, S. Dilly, 2018, Journal of medicinal chemistry.

Broad-spectrum antiviral activity of naproxen: from Influenza A to SARS-CoV-2 Coronavirus

F. Berenbaum, V. Maréchal, M. Rosa-Calatrava, 2020, bioRxiv.

Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process.

S. Dilly, B. Pirotte, P. Lebrun, 2011, Bioorganic & medicinal chemistry.

A double-blind, randomised, crossover comparison of granisetron and ondansetron in 5-day fractionated chemotherapy: Assessment of efficacy, safety and patient preference

S. Dilly, D. Cupissol, L. Goedhals, 1994 .

Design, Synthesis, and Evaluation of Novel Pyruvate Dehydrogenase Kinase Inhibitors.

V. Lambert, A. Noël, B. Elmoualij, 2022, Medicinal chemistry (Shariqah (United Arab Emirates)).

Are granisetron and ondansetron equivalent in the clinic?

S. Dilly, 1992, European journal of cancer.

A double-blind, randomised, crossover comparison of granisetron and ondansetron in 5-day fractionated chemotherapy: assessment of efficacy, safety and patient preference. The Granisetron Study Group.

S. Dilly, D. Cupissol, L. Goedhals, 1994, European journal of cancer.

Homology modeling of MT1 and MT2 receptors.

G. Vergoten, D. Lesieur, P. Chavatte, 2008, European journal of medicinal chemistry.

172 Cyclosporine Inhalation Solution Does Not Improve Bronchiolitis Obliterans Syndrome-Free Survival Following Lung Transplant: Results from the CYCLIST Trial

J. Golden, M. Zamora, S. Dilly, 2012 .

Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus

F. Berenbaum, V. Maréchal, E. Bouřa, 2021, Molecules.

Targeting M2 Macrophages with a Novel NADPH Oxidase Inhibitor

C. Dessy, S. Dilly, S. Solier, 2023, Antioxidants.

Molecular modeling study of 4-phenylpiperazine and 4-phenyl-1,2,3,6-tetrahydropyridine derivatives: a new step towards the design of high-affinity 5-HT1A ligands.

S. Dilly, J. Liégeois, A. Graulich, 2010, Bioorganic & medicinal chemistry letters.

The 5-HT1A Agonism Potential of Substituted Piperazine-Ethyl-Amide Derivatives Is Conserved in the Hexyl Homologues: Molecular Modeling and Pharmacological Evaluation

Sébastien Dilly, Jean-François Liégeois, Jacqueline Scuvée-Moreau, 2011, J. Chem. Inf. Model..

Interaction of clozapine and its nitrenium ion with rat D2 dopamine receptors: in vitro binding and computational study

Sébastien Dilly, Jean-François Liégeois, S. Dilly, 2011, J. Comput. Aided Mol. Des..

Structural Insights into 5-HT1A/D4 Selectivity of WAY-100635 Analogues: Molecular Modeling, Synthesis, and in Vitro Binding

Sébastien Dilly, Jean-François Liégeois, S. Dilly, 2016, J. Chem. Inf. Model..

Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors.

V. Setola, B. Roth, J. Scuvée-Moreau, 2012, Bioorganic & medicinal chemistry letters.

The interactions of apamin and tetraethylammonium are differentially affected by single mutations in the pore mouth of small conductance calcium-activated potassium (SK) channels.

D. Snyders, Cédric Lamy, S. Dilly, 2013, Biochemical pharmacology.

Ion‐Channel Modulators: More Diversity Than Previously Thought

N. Marrion, Cédric Lamy, S. Dilly, 2011, Chembiochem : a European journal of chemical biology.

Design of Light-Sensitive Triggers for Endothelial NO-Synthase Activation

E. Deprez, S. Dilly, L. Roman, 2020, Antioxidants.

Molecular modelling of phthalates – PPARs interactions

P. Chavatte, M. Luyckx, N. Kambia, 2008, Journal of enzyme inhibition and medicinal chemistry.

In Silico Identification of a Key Residue for Substrate Recognition of the Riboflavin Membrane Transporter RFVT3

Sébastien Dilly, Mélanie Garnier, Nada Taib, 2020, J. Chem. Inf. Model..

V. Lambert, A. Noël, B. Elmoualij, 2013 .

Identification of a pharmacophore of SKCa channel blockers

P. Chavatte, A. Farce, S. Dilly, 2005, Journal of enzyme inhibition and medicinal chemistry.

Granisetron (Kytril) clinical safety and tolerance.

S. Dilly, 1994, Seminars in oncology.

Chemical modifications of the N-methyl-laudanosine scaffold point to new directions for SK channels exploration.

J. Wouters, S. Dilly, J. Liégeois, 2014, Bioorganic & medicinal chemistry letters.