P. Winnard

发表

Nanoplex delivery of siRNA and prodrug enzyme for multimodality image-guided molecular pathway targeted cancer therapy.

Dmitri Artemov, Zaver M Bhujwalla, Z. Bhujwalla, 2010, ACS nano.

Organ-specific isogenic metastatic breast cancer cell lines exhibit distinct Raman spectral signatures and metabolomes

R. Dasari, J. Kang, F. Vesuna, 2017, Oncotarget.

Prodrug enzymes and their applications in image-guided therapy of cancer: tracking prodrug enzymes to minimize collateral damage

Z. Bhujwalla, Cong Li, Marie-France Penet, 2012, Drug Delivery and Translational Research.

DEVELOPMENT OF NEEDLE-BASED MICROENDOSCOPY FOR FLUORESCENCE MOLECULAR IMAGING OF BREAST TUMOR MODELS

V. Raman, Chao-wei Chen, Yu Chen, 2009 .

Choline kinase overexpression increases invasiveness and drug resistance of human breast cancer cells

V. Raman, Z. Bhujwalla, Marie-France Penet, 2010, NMR in biomedicine.

Integrated Optical Coherence Tomography (OCT) and Fluorescence Laminar Optical Tomography (FLOT)

Shuai Yuan, Kristine Glunde, Venu Raman, 2010, IEEE Journal of Selected Topics in Quantum Electronics.

Integrated Optical Coherence Tomography (OCT) and Fluorescence Laminar Optical Tomography (FLOT)

Shuai Yuan, Yu Chen, V. Raman, 2010, IEEE Journal of Selected Topics in Quantum Electronics.

Conjugation of poly-L-lysine to bacterial cytosine deaminase improves the efficacy of enzyme/prodrug cancer therapy.

Z. Bhujwalla, Cong Li, Marie-France Penet, 2008, Journal of medicinal chemistry.

Expression of DDX3 Is Directly Modulated by Hypoxia Inducible Factor-1 Alpha in Breast Epithelial Cells

B. Krishnamachary, F. Vesuna, V. Raman, 2011, PloS one.

Expression of DDX 3 Is Directly Modulated by Hypoxia Inducible Factor-1 Alpha in Breast Epithelial Cells

B. Krishnamachary, F. Vesuna, V. Raman, 2011 .

Developing MR reporter genes: promises and pitfalls

J. Bulte, P. V. van Zijl, A. Gilad, 2007, NMR in biomedicine.

Neoplastic transformation of breast epithelial cells by genotoxic stress

V. Raman, P. Winnard, M. Botlagunta, 2010, BMC Cancer.

Delayed Progression of Lung Metastases Following Delivery of a Prodrug-activating Enzyme.

M. Black, B. Krishnamachary, V. Raman, 2017, Anticancer research.

Label-free Raman spectroscopy provides early determination and precise localization of breast cancer-colonized bone alterations† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc02905e

V. Raman, I. Barman, M. Doucet, 2017, Chemical science.

Divergent organ-specific isogenic metastatic cell lines identified using multi-omics exhibit differential drug sensitivity

F. Vesuna, V. Raman, P. Winnard, 2020, PloS one.

Development of novel chimeric transmembrane proteins for multimodality imaging of cancer cells

V. Raman, P. Winnard, D. Artemov, 2007, Cancer biology & therapy.

Brain metabolites in cholinergic and glutamatergic pathways are altered by pancreatic cancer cachexia

K. Horton, B. Krishnamachary, A. Maitra, 2020, Journal of cachexia, sarcopenia and muscle.

Pretargeting of bacterial endocarditis in rats with streptavidin and 111In-labeled biotin.

P. Winnard, M. Rusckowski, D. Hnatowich, 1999, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

NZ51, a ring-expanded nucleoside analog, inhibits motility and viability of breast cancer cells by targeting the RNA helicase DDX3

F. Vesuna, V. Raman, Y. Bergman, 2015, Oncotarget.

Technetium-99m labeling of DNA oligonucleotides.

C. Cantor, C. Smith, P. Winnard, 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Image-Guided Enzyme/Prodrug Cancer Therapy

Z. Bhujwalla, Cong Li, Marie-France Penet, 2008, Clinical Cancer Research.

Directly and indirectly technetium-99m-labeled antibodies--a comparison of in vitro and animal in vivo properties.

P. Winnard, F. Virzi, M. Rusckowski, 1993, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Facile synthesis of 1-(acetic acid)-4,7,10-tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraaza-cyclododecane: a reactive precursor chelating agent.

Z. Bhujwalla, Cong Li, P. Winnard, 2009, Tetrahedron letters.

Detection of Pancreatic Cancer-Induced Cachexia Using a Fluorescent Myoblast Reporter System and Analysis of Metabolite Abundance.

A. Maitra, Z. Bhujwalla, S. Bharti, 2016, Cancer research.

Can a cysteine challenge assay predict the in vivo behavior of 99mTc-labeled antibodies?

P. Winnard, F. Virzi, M. Rusckowski, 1994, Nuclear medicine and biology.

Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.

V. Raman, Takafumi Suzuki, Masayuki Yamamoto, 2010, Carcinogenesis.

Robust expression of transgenes in MCF-7 breast cancer cells is expression vector-dependent.

V. Raman, P. Winnard, Y. Mironchik, 2004, BioTechniques.

Understanding cancer-induced cachexia: imaging the flame and its fuel

M. Jacobs, Z. Bhujwalla, Marie-France Penet, 2011, Current opinion in supportive and palliative care.

Targeting host DEAD-box RNA helicase DDX3X for treating viral infections.

F. Vesuna, V. Raman, P. Winnard, 2020, Antiviral research.

Role of DDX3 in the pathogenesis of inflammatory bowel disease

P. V. van Diest, F. Vesuna, V. Raman, 2017, Oncotarget.

Artificial reporter gene providing MRI contrast based on proton exchange

Piotr Walczak, Venu Raman, Michael T McMahon, 2007, Nature Biotechnology.

RK-33, a small molecule inhibitor of host RNA helicase DDX3, suppresses multiple variants of SARS-CoV-2

R. Scharpf, K. Kehn-Hall, F. Vesuna, 2022, bioRxiv.

Targeting DDX3 in Medulloblastoma Using the Small Molecule Inhibitor RK-33

P. V. van Diest, F. Vesuna, V. Raman, 2018, Translational oncology.

Teleost introns are characterized by a high A+T content.

M. Vayda, B. Sidell, P. Winnard, 2002, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Localized hypoxia results in spatially heterogeneous metabolic signatures in breast tumor models.

R. Heeren, V. Raman, Z. Bhujwalla, 2012, Neoplasia.

Characterizing vascular parameters in hypoxic regions: a combined magnetic resonance and optical imaging study of a human prostate cancer model.

Arvind P Pathak, Dmitri Artemov, Venu Raman, 2006, Cancer research.

PSMA-targeted theranostic nanoplex for prostate cancer therapy.

M. Pomper, Z. Bhujwalla, S. Banerjee, 2012, ACS nano.

Molecular Imaging of Metastatic Potential

M. Pomper, A. Pathak, V. Raman, 2008, Journal of Nuclear Medicine.

HOXA5-Twist Interaction Alters p53 Homeostasis in Breast Cancer Cells*

V. Raman, F. Wildes, P. Winnard, 2005, Journal of Biological Chemistry.

Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer.

P. V. van Diest, A. Pathak, F. Vesuna, 2005, Cancer research.

Review Article Developing MR reporter genes: promises and pitfalls

J. Bulte, P. Zijl, A. Gilad, 2007 .

Noninvasive optical tracking of red fluorescent protein-expressing cancer cells in a model of metastatic breast cancer.

V. Raman, P. Winnard, Jessica B Kluth, 2006, Neoplasia.

Isogenic Cell Lines Derived from Specific Organ Metastases Exhibit Divergent Cytogenomic Aberrations

V. Raman, L. Morsberger, P. Winnard, 2023, Cancers.

Enhanced green fluorescent protein as an alternative control reporter to Renilla luciferase.

F. Vesuna, V. Raman, P. Winnard, 2005, Analytical biochemistry.

Cold-Temperature Adaptation of Muscle Creatine Kinase from an Antartic Teleost (Chaenocephalus Aceratus)

P. Winnard, 2001 .

Isolation, characterization and nucleotide sequence of the muscle isoforms of creatine kinase from the Antarctic teleost Chaenocephalus aceratus.

R. Cashon, M. Vayda, B. Sidell, 2003, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Peptides derived from type IV collagen, CXC chemokines, and thrombospondin-1 domain-containing proteins inhibit neovascularization and suppress tumor growth in MDA-MB-231 breast cancer xenografts.

A. Popel, F. Vesuna, V. Raman, 2009, Neoplasia.

HOXA5 regulates hMLH1 expression in breast cancer cells.

F. Vesuna, V. Raman, P. Winnard, 2006, Neoplasia.

Stable integration of an empty vector in MCF-7 cells greatly alters the karyotype.

V. Raman, C. Glackin, P. Winnard, 2006, Cancer genetics and cytogenetics.

Investigations of directly labeling antibodies with rhenium-188.

P. Winnard, M. Rusckowski, D. Hnatowich, 1996, The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology.

Hypoxia regulates choline kinase expression through hypoxia-inducible factor-1 alpha signaling in a human prostate cancer model.

F. Vesuna, V. Raman, Z. Bhujwalla, 2008, Cancer research.

Prodrug enzymes and their applications in image-guided therapy of cancer: tracking prodrug enzymes to minimize collateral damage

Z. Bhujwalla, Cong Li, Marie-France Penet, 2012, Drug Delivery and Translational Research.

Combined MR, fluorescence and histology imaging strategy in a human breast tumor xenograft model

Kristine Glunde, Dmitri Artemov, Venu Raman, 2013, NMR in biomedicine.

Real time non‐invasive imaging of receptor–ligand interactions in vivo

V. Raman, P. Winnard, 2003, Journal of cellular biochemistry.

Preparation and use of NHS-MAG3 for technetium-99m labeling of DNA.

P. Winnard, M. Rusckowski, D. Hnatowich, 1997, Nuclear medicine and biology.

Comparative properties of a technetium-99m-labeled single-stranded natural DNA and a phosphorothioate derivative in vitro and in mice.

C. Cantor, C. Smith, P. Winnard, 1996, The Journal of pharmacology and experimental therapeutics.

Recombinant metallothionein-conjugated streptavidin labeled with 188Re and 99mTc.

C. Cantor, C. Smith, P. Winnard, 1995, Bioconjugate chemistry.

MALDI-MSI of lipids in a model of breast cancer brain metastasis provides a surrogate measure of ischemia/hypoxia.

V. Raman, P. Winnard, A. Woods, 2023, Molecular and cellular biochemistry.

n spectroscopy provides early determination and precise localization of breast cancer-colonized bone alterations †

V. Raman, I. Barman, M. Doucet, 2018 .

Mass Spectrometric Imaging of Red Fluorescent Protein in Breast Tumor Xenografts

R. Heeren, V. Raman, Z. Bhujwalla, 2013, Journal of The American Society for Mass Spectrometry.

Twist overexpression promotes chromosomal instability in the breast cancer cell line MCF-7.

F. Vesuna, V. Raman, C. Glackin, 2006, Cancer genetics and cytogenetics.

Oncogenic role of DDX3 in breast cancer biogenesis

F. Vesuna, V. Raman, P. Farabaugh, 2008, Oncogene.

Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.

V. Raman, Takafumi Suzuki, Masayuki Yamamoto, 2010, Carcinogenesis.

Peptides derived from type IV collagen, CXC chemokines, and thrombospondin-1 domain-containing proteins inhibit neovascularization and suppress tumor growth in MDA-MB-231 breast cancer xenografts.

A. Popel, F. Vesuna, V. Raman, 2009, Neoplasia.

Targeting RNA Helicase DDX3X with a Small Molecule Inhibitor for Breast Cancer Bone Metastasis Treatment.

P. V. van Diest, F. Vesuna, P. Winnard, 2024, Cancer letters.