S. Denoyelle

发表

A structure–activity investigation of hemifluorinated bifunctional bolaamphiphiles designed for gene delivery

P. Vuillaume, M. Brunelle, S. Laurent-Lewandowski, 2009 .

Synthesis and preliminary biological studies of hemifluorinated bifunctional bolaamphiphiles designed for gene delivery

P. Vuillaume, M. Brunelle, A. Polidori, 2006 .

Chemical Genetics Identify eIF2α Kinase Heme Regulated Inhibitor as Anti-Cancer Target

J. Supko, S. Denoyelle, J. Halperin, 2011, Nature chemical biology.

Synthesis and SAR study of novel 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as potent eIF2·GTP·Met-tRNAiMet ternary complex inhibitors.

Ying Zhang, S. Denoyelle, J. Halperin, 2013, European journal of medicinal chemistry.

Tumor suppression by small molecule inhibitors of translation initiation

G. Wagner, Nancy Zhang, J. Supko, 2012, Oncotarget.

GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner

S. Cantel, H. Schiöth, A. Giovambattista, 2022, Cellular and Molecular Life Sciences.

The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist

A. Moulin, Jean Martinez, J. Fehrentz, 2012, Amino Acids.

Synthesis of Thieno[3,2‐e][1,4]diazepin‐2‐ones: Application of an Uncatalysed Pictet–Spengler Reaction

Jean Martínez, S. Denoyelle, V. Lisowski, 2015 .

Synthesis and Evaluation of Hybrid Bis‐cationic Salts as Antimalarial Drugs

H. Vial, T. Durand, S. Denoyelle, 2010, ChemMedChem.

A Novel Truncated Liver Enriched Antimicrobial Peptide-2 Palmitoylated at its N-Terminal Antagonizes Effects of Ghrelin

S. Cantel, J. Fehrentz, S. Denoyelle, 2022, The Journal of Pharmacology and Experimental Therapeutics.

A novel truncated LEAP2 palmitoylated at its N-terminal antagonizes effects of ghrelin

S. Cantel, J. Fehrentz, S. Denoyelle, 2022 .

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling*

Jean Martinez, J. Fehrentz, S. Denoyelle, 2015, The Journal of Biological Chemistry.

Design and Characterization of a Triazole-Based Growth Hormone Secretagogue Receptor Modulator Inhibiting the Glucoregulatory and Feeding Actions of Ghrelin.

S. Cantel, J. Fehrentz, S. Denoyelle, 2022, Biochemical pharmacology.

N-Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor.

S. Cantel, J. Fehrentz, S. Denoyelle, 2018, Journal of medicinal chemistry.

New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center.

A. Blayo, Jean Martinez, J. Fehrentz, 2016, Bioorganic & medicinal chemistry letters.

Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials.

H. Vial, F. Bressolle, T. Durand, 2019, Bioorganic & medicinal chemistry letters.

Selective C-acylation of 2-aminoimidazo[1,2-a]pyridine: application to the synthesis of imidazopyridine-fused [1,3]diazepinones.

Jean Martínez, E. Moreau, S. Denoyelle, 2012, The Journal of organic chemistry.

In vitro inhibition of translation initiation by N,N'-diarylureas--potential anti-cancer agents.

S. Denoyelle, J. Halperin, M. Chorev, 2012, Bioorganic & medicinal chemistry letters.

Role of Symmetry in 3,3-Diphenyl-1,3-dihydroindol-2-one Derivatives as Inhibitors of Translation Initiation.

Ying Zhang, S. Denoyelle, Jing Fan, 2022, Bioorganic & medicinal chemistry letters.

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation

H. Hamm, G. Ferry, J. Boutin, 2018, Proceedings of the National Academy of Sciences.

Allosteric modulation of ghrelin receptor signaling by lipids

P. Bisch, S. Cantel, L. Catoire, 2021, Nature Communications.

New trisubstituted 1,2,4-triazoles as ghrelin receptor antagonists.

A. Blayo, Jean Martinez, J. Fehrentz, 2015, Bioorganic & medicinal chemistry letters.

Synthesis and Preliminary Biological Studies of Hemifluorinated Bifunctional Bolaamphiphiles Designed for Gene Delivery.

P. Vuillaume, M. Brunelle, A. Polidori, 2006 .

The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist

A. Moulin, Jean Martinez, J. Fehrentz, 2013, Amino Acids.

Circulating ghrelin crosses the blood-cerebrospinal fluid barrier via growth hormone secretagogue receptor dependent and independent mechanisms

S. Cantel, J. Fehrentz, V. Prévot, 2021, Molecular and Cellular Endocrinology.

Development of a novel fluorescent ligand of growth hormone secretagogue receptor based on the N-Terminal Leap2 region

S. Cantel, J. Fehrentz, S. Denoyelle, 2019, Molecular and Cellular Endocrinology.

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex

D. Pérahia, E. Trinquet, B. Mouillac, 2015, Proceedings of the National Academy of Sciences.

Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy

G. Cruciani, A. Torsello, E. Conte, 2023, Frontiers in Immunology.

Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor

P. Bisch, D. Pérahia, S. Cantel, 2021, eLife.