Sandeep Rana

发表

Combination of nanogel polyethylene glycol-polyethylenimine and 6(hydroxymethyl)-1,4-anthracenedione as an anticancer nanomedicine.

D. Troyer, C. Ganta, Aibin Shi, 2008, Journal of nanoscience and nanotechnology.

Development of 1-((1,4-trans)-4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2α) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response.

Peimin Wang, B. Hammock, C. Morisseau, 2017, Journal of medicinal chemistry.

Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase.

B. Hammock, C. Morisseau, Sandeep Rana, 2013, Journal of Medicinal Chemistry.

Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy

Sandeep Rana, Jacob I. Contreras, A. Natarajan, 2016, Journal of medicinal chemistry.

Isatin Derived Spirocyclic Analogues with α-Methylene-γ-butyrolactone as Anticancer Agents: A Structure-Activity Relationship Study.

Sandeep Rana, Jacob I. Contreras, A. Natarajan, 2016, Journal of medicinal chemistry.

Dimers of isatin derived α-methylene-γ-butyrolactone as potent anti-cancer agents.

T. Huxford, Sandeep Rana, A. Natarajan, 2022, Bioorganic & medicinal chemistry letters.

Spirocyclic dimer SpiD7 activates the unfolded protein response to selectively inhibit growth and induce apoptosis of cancer cells

Nicholas T. Woods, Sandeep Rana, A. Natarajan, 2022, The Journal of biological chemistry.

Micellar formulation of indocyanine green for phototherapy of melanoma.

R. Mahato, Sandeep Rana, A. Natarajan, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC).

Sandeep Rana, Jacob I. Contreras, A. Natarajan, 2017, Chemical communications.

PIK3C3 Inhibition Promotes Sensitivity to Colon Cancer Therapy by Inhibiting Cancer Stem Cells

C. Hopkins, P. Dhawan, D. Oupický, 2021, Cancers.

Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy.

Ayrianne J. Crawford, M. Hollingsworth, Sandeep Rana, 2018, ACS chemical biology.

Synthesis, biophysical analysis and biological evaluation of tricyclic pyrones and pyridinones as anti-alzheimer agents

Sandeep Rana, 2009 .

Candidate anti-Aβ fluorene compounds selected from analogs of amyloid imaging agents

K. Lam, R. Cheng, R. Vassar, 2010, Neurobiology of Aging.

Selective degradation of CDK6 by a palbociclib based PROTAC.

M. Bendjennat, Sandeep Rana, A. Natarajan, 2019, Bioorganic & medicinal chemistry letters.

Small molecule induced polymerization of BCL6 facilitates SIAH1 mediated degradation

Sandeep Rana, A. Natarajan, 2021, Signal Transduction and Targeted Therapy.

Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth

Ayrianne J. Crawford, G. Borgstahl, M. Hollingsworth, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Face selective reduction of the exocyclic double bond in isatin derived spirocyclic lactones.

Sandeep Rana, A. Natarajan, 2013, Organic & biomolecular chemistry.

Synthesis, Anticancer Evaluation and DNA‐Binding Spectroscopic Insights of Quinoline‐Based 1,3,4‐Oxadiazole‐1,2,3‐triazole Conjugates

S. Mehdi, M. M. Rizvi, Sandeep Rana, 2019, ChemistrySelect.

Synthesis and anti-breast cancer activities of substituted quinolines.

P. Chiang, Aibin Shi, Srinivas K. Battina, 2008, Bioorganic & medicinal chemistry letters.

Irreversible binding of an anticancer compound (BI-94) to plasma proteins

Sandeep Rana, A. Natarajan, N. Gautam, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy.

Sandeep Rana, Jacob I. Contreras, A. Natarajan, 2021, European journal of medicinal chemistry.

Novel Selective and Irreversible Mosquito Acetylcholinesterase Inhibitors for Controlling Malaria and Other Mosquito-Borne Diseases

Y. Pang, Sandeep Rana, Haobo Jiang, 2013, Scientific Reports.

Inhibitors, PROTACs and Molecular Glues as Diverse Therapeutic Modalities to Target Cyclin-Dependent Kinase

Sandeep Rana, A. Natarajan, Sarbjit Singh, 2021, Cancers.

EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling

P. Singh, C. Guda, A. Barnekow, 2020, Molecular and Cellular Biology.

Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction

G. Borgstahl, Sandeep Rana, J. Lovelace, 2021, PloS one.

Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax.

Nicholas T. Woods, M. Naldrett, Sandeep Rana, 2021, Bioorganic & medicinal chemistry letters.

Symbiotic Prodrugs (SymProDs) Dual Targeting of NFkappaB and CDK.

Sandeep Rana, Jacob I. Contreras, A. Natarajan, 2020, Chemical biology & drug design.

CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax

Ayrianne J. Crawford, M. Hollingsworth, M. Bendjennat, 2019, Molecular Pharmacology.

Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.

Sandeep Rana, A. Natarajan, Elizabeth C Blowers, 2015, Journal of medicinal chemistry.

Small molecule binding to inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner.

Nicholas Y. Palermo, T. Huxford, M. Ouellette, 2021, Chemical communications.

A quinoxaline urea analog uncouples inflammatory and pro-survival functions of IKKβ.

M. Naramura, Sandeep Rana, A. Natarajan, 2015, Immunology letters.

Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases

S. Brimijoin, Y. Pang, Sandeep Rana, 2009, PloS one.

A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1

G. Adelmant, J. Marto, K. Shah, 2019, Nature Communications.

Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy

M. Hollingsworth, J. Black, M. Brattain, 2017, Oncotarget.

Tricyclic pyrone compounds prevent aggregation and reverse cellular phenotypes caused by expression of mutant huntingtin protein in striatal neurons

C. McMurray, Sandeep Rana, D. Hua, 2009, BMC Neuroscience.

Synthesis of aminopyrazole analogs and their evaluation as CDK inhibitors for cancer therapy.

Sandeep Rana, A. Natarajan, M. Zahid, 2018, Bioorganic & medicinal chemistry letters.

Resurgence of Dengue-like and Chikungunya-like illness in New Delhi, India During 2016

I. Naqvi, Sandeep Rana, S. Broor, 2016 .

A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid‐β oligomeric complexes

Takeo Iwamoto, T. Iwamoto, Srinivas K. Battina, 2006, Journal of neurochemistry.

Synthesis and SAR studies of novel 1,2,4-oxadiazole-sulfonamide based compounds as potential anticancer agents for colorectal cancer therapy.

M. M. Rizvi, A. Hussain, Sandeep Rana, 2020, Bioorganic chemistry.

Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo

Aibin Shi, Sandeep Rana, D. Hua, 2009, Journal of neurochemistry.

Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Aβ oligomer-induced cytotoxicity

K. Lam, R. Diaz-Avalos, R. Cheng, 2007, Brain Research.

Syntheses of tricyclic pyrones and pyridinones and protection of Abeta-peptide induced MC65 neuronal cell death.

Sandeep Rana, D. Hua, H. Hong, 2009, Bioorganic & medicinal chemistry letters.