J. Leroux

发表

On the role of methacrylic acid copolymers in the intracellular delivery of antisense oligonucleotides.

M. Yessine, C. Meier, H. Petereit, 2006, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Study of the Micellization Behavior of Different Order Amino Block Copolymers with Heparin

Marie-Hélène Dufresne, Marie-Hélène Dufresne, J. Leroux, 2004, Pharmaceutical Research.

Predicting the Solubility of the Anti-Cancer Agent Docetaxel in Small Molecule Excipients using Computational Methods

J. Leroux, C. Allen, L. Huynh, 2007, Pharmaceutical Research.

Magnetic nanoparticles encapsulated into biodegradable microparticles steered with an upgraded magnetic resonance imaging system for tumor chemoembolization.

S. Martel, P. Pouponneau, J. Leroux, 2009, Biomaterials.

Co-encapsulation of magnetic nanoparticles and doxorubicin into biodegradable microcarriers for deep tissue targeting by vascular MRI navigation.

S. Martel, L. Gaboury, P. Pouponneau, 2011, Biomaterials.

In situ-forming hydrogels--review of temperature-sensitive systems.

J. Leroux, È. Ruel-Gariépy, Jean-Christophe Leroux, 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Membrane-destabilizing polyanions: interaction with lipid bilayers and endosomal escape of biomacromolecules.

M. Yessine, J. Leroux, Marie-Andrée Yessine, 2004, Advanced drug delivery reviews.

Polyester-based micelles and nanoparticles for the parenteral delivery of taxanes.

R. Marchessault, J. Leroux, G. Gaucher, 2010, Journal of controlled release : official journal of the Controlled Release Society.

First report on the efficacy of l-alanine-based in situ-forming implants for the long-term parenteral delivery of drugs.

J. Leroux, Aude Motulsky, H. Ong, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as polymeric emulsifier for the preparation of biodegradable nanoparticles.

J. Leroux, G. Gaucher, F. Ravenelle, 2007, Journal of pharmaceutical sciences.

Design of targeted lipid nanocapsules by conjugation of whole antibodies and antibody Fab' fragments.

J. Benoit, A. Clavreul, J. Leroux, 2007, Biomaterials.

Prevention Measures and Exploratory Pharmacological Treatments of Celiac Disease

J. Leroux, E. Verdu, G. Fuhrmann, 2010, The American Journal of Gastroenterology.

Long circulating lipid nanocapsules for drug detoxification.

J. Leroux, K. Wasan, A. Dhanikula, 2007, Biomaterials.

Polymeric micelles for oral drug delivery.

J. Leroux, A. Furtos, G. Gaucher, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

An investigation on the use of tributyrin nanoemulsions for docetaxel delivery

J. Leroux, C. Allen, L. Huynh, 2008 .

Reverse polymeric micelles for pharmaceutical applications.

Hui Gao, J. Leroux, Marie-Christine G. Jones, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Synthesis of novel amphiphilic star-shaped poly(ε-caprolactone)-block-poly(N-(2-hydroxypropyl)methacrylamide) by combination of ring-opening and chain transfer polymerization

J. Leroux, B. S. Lele, 2002 .

pH-sensitive unimolecular polymeric micelles: synthesis of a novel drug carrier.

J. Leroux, Marie-Christine G. Jones, M. Ranger, 2003, Bioconjugate chemistry.

Novel Polymeric Micelles Based on the Amphiphilic Diblock Copolymer Poly(N-vinyl-2-pyrrolidone)-block-poly(D,L-lactide)

J. Leroux, M. Ranger, A. Benahmed, 2001, Pharmaceutical Research.

Enhancement of oral bioavailability of poorly water-soluble drugs by poly(ethylene glycol)-block-poly(alkyl acrylate-co-methacrylic acid) self-assemblies.

J. Leroux, V. Sant, Damon C. Smith, 2005, Journal of controlled release : official journal of the Controlled Release Society.

A thermosensitive chitosan-based hydrogel for the local delivery of paclitaxel.

Mohammed Berrada, M. Shive, J. Leroux, 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Tyrosine-based rivastigmine-loaded organogels in the treatment of Alzheimer's disease.

R. Quirion, G. Bastiat, J. Leroux, 2010, Biomaterials.

Irradiating or autoclaving chitosan/polyol solutions: effect on thermogelling chitosan-beta-glycerophosphate systems.

J. Leroux, C. Chaput, C. Jarry, 2002, Chemical & pharmaceutical bulletin.

Biodegradable Nanospheres Containing Phthalocyanines and Naphthalocyanines for Targeted Photodynamic Tumor Therapy

V. Lenaerts, J. V. van Lier, R. Ouellet, 1991, Pharmaceutical Research.

Pharmacokinetics and biodistribution of N-isopropylacrylamide copolymers for the design of pH-sensitive liposomes.

J. Leroux, K. Wasan, N. Bertrand, 2009, Biomaterials.

Pharmaceutical organogels prepared from aromatic amino acid derivatives.

G. Bastiat, J. Leroux, 2009, Journal of materials chemistry.

Synthesis and enzymatic stability of PEGylated oligonucleotide duplexes and their self-assemblies with polyamidoamine dendrimers.

Mahmoud Elsabahy, J. Leroux, Mingzhen Zhang, 2008, Soft matter.

Polymeric binders suppress gliadin-induced toxicity in the intestinal epithelium.

N. Rivard, J. Leroux, E. Verdu, 2009, Gastroenterology.

Gliadin-Induced Toxicity in the ntestinal Epithelium

J. Leroux, E. Verdu, C. David, 2022 .

BL-7010 Demonstrates Specific Binding to Gliadin and Reduces Gluten-Associated Pathology in a Chronic Mouse Model of Gliadin Sensitivity

J. Murray, A. Varvak, J. Leroux, 2014, PloS one.

Brain targeting using novel lipid nanovectors.

J. Benoit, A. Clavreul, J. Leroux, 2008, Journal of controlled release : official journal of the Controlled Release Society.

A Novel One-Step Drug Loading Procedure for Water-Soluble Amphiphilic Nanocarriers

Marie-Hélène Dufresne, J. Leroux, M. Ranger, 2006, Pharmaceutical Research.

ADHERENCE TO CHOLINESTERASE INHIBITORS IN PATIENTS WITH ALZHEIMER'S DISEASE

M. Kergoat, J. Leroux, L. Blais, 2009, Journal of the American Geriatrics Society.

Long-circulating poly(ethylene glycol)-coated emulsions to target solid tumors.

J. Leroux, C. Allen, P. Delmas, 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

In Situ-Forming Oleogel Implant for Rivastigmine Delivery

M. Lafleur, G. Bastiat, J. Leroux, 2008, Pharmaceutical Research.

Influence of physical parameters and lubricants on the compaction properties of granulated and non-granulated cross-linked high amylose starch.

V. Lenaerts, J. Leroux, E. Doelker, 2002, Chemical & pharmaceutical bulletin.

From well‐defined diblock copolymers prepared by a versatile atom transfer radical polymerization method to supramolecular assemblies

M. Yessine, J. Leroux, Marie-Christine G. Jones, 2001 .

In situ-Forming Pharmaceutical Organogels Based on the Self-Assembly of L-Alanine Derivatives

Aude Motulsky, J. Leroux, P. Delmas, 2004, Pharmaceutical Research.

Organogels and their use in drug delivery--a review.

Anda Vintiloiu, Jean-Christophe Leroux, J. Leroux, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Injectable nanocarriers for biodetoxification.

J. Leroux, Jean-Christophe Leroux, 2007, Nature nanotechnology.

Characterization and biocompatibility of organogels based on L-alanine for parenteral drug delivery implants.

Aude Motulsky, Jean-Pierre Benoit, Frank Boury, 2005, Biomaterials.

Annealing of magnetic nanoparticles for their encapsulation into microcarriers guided by vascular magnetic resonance navigation

S. Martel, P. Pouponneau, V. Segura, 2012, Journal of Nanoparticle Research.

Rescue of amitriptyline-intoxicated hearts with nanosized vesicles.

J. Leroux, D. Lamontagne, A. Dhanikula, 2007, Cardiovascular research.

Chitosan : A natural polycation with multiple applications

J. Leroux, È. Ruel-Gariépy, 2006 .

Biocompatibility of thermosensitive chitosan-based hydrogels: an in vivo experimental approach to injectable biomaterials.

A. Adam, J. Leroux, G. Molinaro, 2002, Biomaterials.

Triblock and star-block copolymers of N-(2-hydroxypropyl)methacrylamide or N-vinyl-2-pyrrolidone and d,l-lactide: synthesis and self-assembling properties in water

J. Leroux, N. Kang, 2004 .

Autonomous gel/enzyme oscillator fueled by glucose: Preliminary evidence for oscillations.

R. Siegel, J. Leroux, 1999, Chaos.

Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: preparation and characterization.

J. Leroux, V. Sant, Damon C. Smith, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Micelles in anticancer drug delivery

J. Leroux, M. Ranger, D. L. Garrec, 2004 .

Interaction of alpha-gliadin with polyanions: design considerations for sequestrants used in supportive treatment of celiac disease.

M. Subirade, J. Leroux, L. Liang, 2010, Biopolymers.

Preparation and in vivo evaluation of PEGylated spherulite formulations.

Didier Hoarau, E. Roux, J. Leroux, 2005, Biochimica et biophysica acta.

Evaluation of pegylated lipid nanocapsules versus complement system activation and macrophage uptake.

J. Benoit, C. Passirani, A. Vonarbourg, 2006, Journal of biomedical materials research. Part A.

Novel Long-Circulating Lipid Nanocapsules

E. Roux, J. Leroux, P. Delmas, 2004, Pharmaceutical Research.

Improving extracellular vesicles production through a Bayesian optimization-based experimental design.

J. Leroux, P. Arosio, H. Narayanan, 2022, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Injectable nanocarriers for biodetoxification Hospitals routinely treat patients suffering from overdoses of drugs

J. Leroux, 2007 .

The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues.

J. Murray, N. Rivard, J. Leroux, 2012, Gastroenterology.

The journey of a drug-carrier in the body: an anatomo-physiological perspective.

Nicolas Bertrand, J. Leroux, Jean-Christophe Leroux, 2012, Journal of controlled release : official journal of the Controlled Release Society.

pH-responsive polymeric micelles of poly(ethylene glycol)-b-poly(alkyl(meth)acrylate-co-methacrylic acid): influence of the copolymer composition on self-assembling properties and release of candesartan cilexetil.

J. Leroux, Jean-Christophe Leroux, F. Ravenelle, 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Preparation and purification of polyisohexylcyanoacrylate nanocapsules

V. Lenaerts, J. Leroux, F. Chouinard, 1991 .

Novel Role of the Serine Protease Inhibitor Elafin in Gluten-Related Disorders

J. Murray, Jean-Paul Motta, Jessica D. Schulz, 2014, The American Journal of Gastroenterology.

Enhancement of docetaxel solubility via conjugation of formulation-compatible moieties.

J. Leroux, C. Allen, L. Huynh, 2009, Organic & biomolecular chemistry.

3D printing of a controlled urea delivery device for the prevention of tooth decay.

J. Leroux, V. Berger, Marina Green Buzhor, 2022, International journal of pharmaceutics.

Interaction of α‐gliadin with poly(HEMA‐co‐SS): Structural characterization and biological implication

M. Subirade, J. Leroux, L. Liang, 2009, Biopolymers.

Nanonization of megestrol acetate by laser fragmentation in aqueous milieu.

M. Meunier, J. Leroux, J. Sylvestre, 2011, Journal of controlled release : official journal of the Controlled Release Society.

A Novel One-Step Drug-Loading Procedure for Water-Soluble Amphiphilic Nanocarriers

Marie-Hélène Dufresne, J. Leroux, M. Ranger, 2004, Pharmaceutical Research.

Fabrication of paclitaxel nanocrystals by femtosecond laser ablation and fragmentation.

M. Meunier, J. Leroux, J. Sylvestre, 2011, Journal of pharmaceutical sciences.

Long Circulating Poly(Ethylene Glycol)-Decorated Lipid Nanocapsules Deliver Docetaxel to Solid Tumors

J. Leroux, A. Dragomir, D. Hoarau, 2006, Pharmaceutical Research.

Copolymers of N‐isopropylacrylamide can trigger pH sensitivity to stable liposomes

Olivier Meyer, D. Papahadjopoulos, J. Leroux, 1998, FEBS letters.

Optimizing pH-responsive Polymeric Micelles for Drug Delivery in a Cancer Photodynamic Therapy Model

V. Lenaerts, J. Taillefer, J. V. van Lier, 2002, Journal of drug targeting.

Characterization and in vitro evaluation of spherulites as sequestering vesicles with potential application in drug detoxification.

M. Lafleur, J. Leroux, Jean-Christophe Leroux, 2006, Biochimica et biophysica acta.

Drug Delivery Research for the Future: Expanding the Nano Horizons and Beyond.

Samir Mitragotri, Ick Chan Kwon, Kinam Park, 2017, Journal of controlled release : official journal of the Controlled Release Society.

pH-sensitive immunoliposomes specific to the CD33 cell surface antigen of leukemic cells.

J. Leroux, P. Simard, 2009, International journal of pharmaceutics.

MR Imaging of Therapeutic Magnetic Microcarriers Guided by Magnetic Resonance Navigation for Targeted Liver Chemoembolization

Sylvain Martel, Gilles Soulez, Gilles Beaudoin, 2014, CardioVascular and Interventional Radiology.

Serum-stable and long-circulating, PEGylated, pH-sensitive liposomes.

J. Benoit, E. Roux, C. Passirani, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Novel injectable neutral solutions of chitosan form biodegradable gels in situ.

J. Leroux, M. Buschmann, J. Leroux, 2000, Biomaterials.

Preparation, characterization, cytotoxicity and biodistribution of docetaxel-loaded polymeric micelle formulations

M. Yessine, J. Leroux, D. Karkan, 2005 .

Characterization of Binary Mixtures Consisting of Cross‐Linked High Amylose Starch and Hydroxypropylmethylcellulose Used in the Preparation of Controlled Release Tablets

V. Lenaerts, J. Leroux, E. Doelker, 2003, Pharmaceutical development and technology.

In vivo fluorescence imaging of exogenous enzyme activity in the gastrointestinal tract

J. Leroux, G. Fuhrmann, 2011, Proceedings of the National Academy of Sciences.

Current status of pH-sensitive liposomes in drug delivery.

M. Zignani, J. Leroux, D. Drummond, 2000, Progress in lipid research.

Polymeric micelles - a new generation of colloidal drug carriers.

M. Jones, J. Leroux, J. Leroux, 1999, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Thermosensitive chitosan-based hydrogel containing liposomes for the delivery of hydrophilic molecules.

J. Leroux, J. Leroux, P. Hildgen, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Kinetics of blood component adsorption on poly(D,L-lactic acid) nanoparticles: evidence of complement C3 component involvement.

L. Balant, R. Gurny, J. Leroux, 1997, Journal of biomedical materials research.

Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice.

R. Gurny, R. Cozens, J. Leroux, 1995, Journal of pharmaceutical sciences.

An investigation on the role of plasma and serum opsonins on the internalization of biodegradable poly(D,L-lactic acid) nanoparticles by human monocytes.

R. Gurny, J. Leroux, J. Leroux, 1995, Life sciences.

Celiac Disease: A Challenging Disease for Pharmaceutical Scientists

J. Leroux, Simon Matoori, G. Fuhrmann, 2013, Pharmaceutical Research.

In vitro evaluation of the stability of proline-specific endopeptidases under simulated gastrointestinal conditions.

J. Leroux, G. Fuhrmann, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation.

J. Leroux, M. Yessine, J. Leroux, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Characterization of thermosensitive chitosan gels for the sustained delivery of drugs.

J. Leroux, J. Leroux, A. Chenite, 2000, International journal of pharmaceutics.

Preparation and characterization of pH-responsive polymeric micelles for the delivery of photosensitizing anticancer drugs.

J. Taillefer, N. Brasseur, J. Leroux, 2000, Journal of pharmaceutical sciences.

Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics.

R. Gurny, J. Leroux, E. Allémann, 1998, Advanced drug delivery reviews.

Tyrosine-based rivastigmine-loaded organogels in the treatment of Alzheimer's disease.

R. Quirion, G. Bastiat, J. Leroux, 2010, Biomaterials.

pH-responsive carriers for enhancing the cytoplasmic delivery of macromolecular drugs

J. Leroux, 2004 .

Preparation and characterization of water-soluble pH-sensitive nanocarriers for drug delivery.

J. Leroux, Marie-Hélène Dufresne, J. Leroux, 2004, International journal of pharmaceutics.