J. Backer

发表

Humanized docking system for assembly of targeting drug delivery complexes.

Tao Hu, Marina V Backer, Joseph M Backer, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Molecular vehicle for target-mediated delivery of therapeutics and diagnostics.

E. Gaidamakova, M. Backer, J. Backer, 2001, Journal of controlled release : official journal of the Controlled Release Society.

Lovastatin blocks N-ras oncogene-induced neuronal differentiation.

J. Backer, C. Mendola, Charmaine E. Mendola, 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials.

Z. Darżynkiewicz, F. Traganos, J. Backer, 1999, International journal of oncology.

Development of Cu-64 labeled EGF for In Vivo PET Imaging of EGFR Expression

J. Backer, 2009 .

Targeted scVEGF/177Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy

F. Blankenberg, M. Backer, J. Backer, 2016, EJNMMI Research.

Novel Receptor for Advanced Glycation End Products‐Blocking Antibody to Treat Diabetic Peripheral Artery Disease

L. Johnson, M. Backer, J. Backer, 2020, Journal of the American Heart Association.

Boron containing macromolecules and nanovehicles as delivery agents for neutron capture therapy.

Robert J. Lee, M. Backer, J. Backer, 2006, Anti-cancer agents in medicinal chemistry.

Fluorescence imaging of vascular endothelial growth factor in tumors for mice embedded in a turbid medium.

Quing Zhu, Baohong Yuan, J. Gamelin, 2010, Journal of biomedical optics.

Noninvasive Imaging of Liposomal Delivery of Superparamagnetic Iron Oxide Nanoparticles to Orthotopic Human Breast Tumor in Mice

S. Sarkar, D. Artemov, M. Backer, 2015, Pharmaceutical Research.

Imaging Vascular Endothelial Growth Factor (VEGF) Receptors in Turpentine-Induced Sterile Thigh Abscesses with Radiolabeled Single-Chain VEGF

F. Blankenberg, M. Backer, J. Backer, 2009, Journal of Nuclear Medicine.

Targeted Systemic Radiotherapy with scVEGF/177Lu Leads to Sustained Disruption of the Tumor Vasculature and Intratumoral Apoptosis

F. Blankenberg, M. Backer, J. Backer, 2011, The Journal of Nuclear Medicine.

Imaging VEGF Receptors and αvβ3 Integrins in a Mouse Hindlimb Ischemia Model of Peripheral Arterial Disease

L. Johnson, A. Schmidt, M. Backer, 2018, Molecular Imaging and Biology.

Genetic control of metastasis

J. Backer, C. Hamby, 1998 .

Urothelial expression of neuropilins and VEGF receptors in control and interstitial cystitis patients.

Xue-Ru Wu, P. Hauser, C. Davis, 2008, American journal of physiology. Renal physiology.

A "dock and lock" approach to preparation of targeted liposomes.

M. Backer, J. Backer, 2010, Methods in molecular biology.

Imaging Early-Stage Metastases Using an 18F-Labeled VEGFR-1-Specific Single Chain VEGF Mutant

Jason S. Lewis, T. Reiner, M. Backer, 2020, Molecular Imaging and Biology.

The HIV-1 nef protein does not have guanine nucleotide binding, GTPase, or autophosphorylating activities.

I. Kovesdi, J. Backer, C. Mendola, 1991, AIDS research and human retroviruses.

ScVEGF-PEG-HBED-CC and scVEGF-PEG-NOTA conjugates: comparison of easy-to-label recombinant proteins for [68Ga]PET imaging of VEGF receptors in angiogenic vasculature.

U. Haberkorn, M. Eder, M. Eisenhut, 2010, Nuclear medicine and biology.

Selective Imaging of Vascular Endothelial Growth Factor Receptor-1 and Receptor-2 in Atherosclerotic Lesions in Diabetic and Non-diabetic ApoE−/− Mice

L. Johnson, M. Backer, J. Backer, 2018, Molecular Imaging and Biology.

Inhibition of Anthrax Protective Antigen Outside and Inside the Cell

K. Claffey, M. Backer, J. Backer, 2006, Antimicrobial Agents and Chemotherapy.

Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells.

M. Backer, J. Backer, J. Paton, 2009, Neoplasia.

VEGF receptor targeted imaging of angiogenic response to limb ischemia in diabetic vs. non-diabetic Yucatan minipigs

L. Johnson, M. Backer, J. Backer, 2020, EJNMMI Research.

Adapter protein for site-specific conjugation of payloads for targeted drug delivery.

M. Backer, Timur I. Gaynutdinov, J. Backer, 2004, Bioconjugate chemistry.

Anti-viral activity of human recombinant heparin-binding proteins HBNF and MK.

J. Backer, M. Ostrander, P. Böhlen, 1992, Biochemical and biophysical research communications.

SLT-VEGF Reduces Lung Metastases, Decreases Tumor Recurrence, and Improves Survival in an Orthotopic Melanoma Model

M. Backer, J. Backer, R. Ackerman, 2010, Toxins.

SPECT and PET imaging of EGF receptors with site-specifically labeled EGF and dimeric EGF.

F. Blankenberg, D. Felsher, M. Backer, 2009, Bioconjugate chemistry.

Receptor-targeted liposomal delivery of boron-containing cholesterol mimics for boron neutron capture therapy (BNCT).

Vimalkumar A. Patel, Robert J. Lee, M. Backer, 2006, Bioconjugate chemistry.

Surface immobilization of active vascular endothelial growth factor via a cysteine-containing tag.

K. Claffey, M. Backer, J. Backer, 2006, Biomaterials.

Differential expression and mutation of NME genes in autologous cultured human melanoma cells with different metastatic potentials.

G. Stafford, J. Backer, C. Mendola, 1995, Biochemical and biophysical research communications.

Chromosomal localization and nucleoside diphosphate kinase activity of human metastasis-suppressor genes NM23-1 and NM23-2.

R. Eddy, T. Shows, R. Chaganti, 1993, Oncogene.

Nanovehicles and High Molecular Weight Delivery Agents for Boron Neutron Capture Therapy

Robert J. Lee, M. Backer, J. Backer, 2007 .

Neutron Capture Therapy of Cancer: Nanoparticles and High Molecular Weight Boron Delivery Agents

Robert J. Lee, M. Backer, J. Backer, 2006 .

The crystal structure of a human nucleoside diphosphate kinase, NM23-H2.

Roger L. Williams, R. Williams, O. Perisic, 1995, Journal of molecular biology.

Kinase Insert Domain Receptor (KDR) Extracellular Immunoglobulin-like Domains 4–7 Contain Structural Features That Block Receptor Dimerization and Vascular Endothelial Growth Factor-induced Signaling*

M. Backer, J. Backer, B. Terman, 2001, The Journal of Biological Chemistry.

Noninvasive assessment of tumor VEGF receptors in response to treatment with pazopanib: a molecular imaging study.

F. Blankenberg, S. Sarkar, M. Backer, 2010, Translational Oncology.

Molecular imaging of VEGF receptors in angiogenic vasculature with single-chain VEGF-based probes

Marina V Backer, Joseph M Backer, Vimalkumar A. Patel, 2007, Nature Medicine.

Vascular endothelial growth factor selectively targets boronated dendrimers to tumor vasculature

K. Claffey, M. Backer, Timur I. Gaynutdinov, 2005, Molecular Cancer Therapeutics.

Nm23‐transfected MDA‐mB‐435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A 31P nuclear magnetic resonance study in vivo and in vitro

R. Gillies, Z. Bhujwalla, E. Aboagye, 1999, Magnetic resonance in medicine.

Inhibition of vascular endothelial growth factor receptor signaling in angiogenic tumor vasculature.

M. Backer, J. Backer, C. Hamby, 2009, Advances in genetics.

Tumor imaging using a standardized radiolabeled adapter protein docked to vascular endothelial growth factor.

Stefanie Mandl, Marina V Backer, Joseph M Backer, 2004, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Assembly of targeting complexes driven by a single-chain antibody.

M. Backer, Timur I. Gaynutdinov, J. Backer, 2004, Journal of immunological methods.

Functionally active VEGF fusion proteins.

M. Backer, J. Backer, 2001, Protein expression and purification.

Shiga-like toxin-VEGF fusion proteins are selectively cytotoxic to endothelial cells overexpressing VEGFR-2.

M. Backer, J. Backer, V. Budker, 2001, Journal of controlled release : official journal of the Controlled Release Society.

Molecular Imaging of Vascular Endothelial Growth Factor Receptors in Graft Arteriosclerosis

Marina V Backer, Joseph M Backer, Mehran M Sadeghi, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Effects of 5 alpha-dihydrotestosterone (DHT) on the transcription of nm23 and c-myc genes in human prostatic LNCaP cells.

J. Backer, H. Tazaki, C. Mendola, 1995, Biochemical and biophysical research communications.

Targeting endothelial cells overexpressing VEGFR-2: selective toxicity of Shiga-like toxin-VEGF fusion proteins.

M. Backer, J. Backer, J M Backer, 2001, Bioconjugate chemistry.

Targeting the unfolded protein response in cancer therapy.

Marina V Backer, Joseph M Backer, Prakash Chinnaiyan, 2011, Methods in enzymology.

Expression of a catalytically inactive H118Y mutant of nm23‐H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells

J. Backer, C. Hamby, R. Abbi, 2000, International journal of cancer.

Analysis of In Situ and Ex Vivo Vascular Endothelial Growth Factor Receptor Expression During Experimental Aortic Aneurysm Progression

M. McConnell, F. Blankenberg, R. Dalman, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Targeting Fluorescent Nanodiamonds to Vascular Endothelial Growth Factor Receptors in Tumor.

Ashlyn G Rickard, G. Palmer, O. Shenderova, 2019, Bioconjugate chemistry.

Selective Imaging of VEGFR-1 and VEGFR-2 Using 89Zr-Labeled Single-Chain VEGF Mutants

Jason S. Lewis, M. Backer, J. Backer, 2016, The Journal of Nuclear Medicine.

Selective imaging of VEGFR-1 and VEGFR-2 receptors using 89 Zr-labeled single-chain VEGF mutants

Jason S. Lewis, M. Backer, J. Backer, 2016 .

Specific targeting of tumor endothelial cells by a shiga-like toxin-vascular endothelial growth factor fusion protein as a novel treatment strategy for pancreatic cancer.

H. Buhr, M. Backer, J. Backer, 2010, Neoplasia.

Imaging VEGF receptor expression to identify accelerated atherosclerosis

L. Johnson, M. Backer, J. Backer, 2014, EJNMMI Research.

GROWTH OF HUMAN OVARIAN TUMOR CELLS IN MICROGRAVITY: OVERVIEW FOR ISS STUDIES.

T. L. Baker, J. Love, R. Widen, 2001 .

Molecular Imaging of Changes in the Prevalence of Vascular Endothelial Growth Factor Receptor in Sunitinib-Treated Murine Mammary Tumors

Carl V Hamby, Joseph M Backer, F. Blankenberg, 2010, Journal of Nuclear Medicine.

Multiplexing with multispectral imaging: from mice to microscopy.

Hisataka Kobayashi, Marina V Backer, Joseph M Backer, 2008, ILAR journal.

Phosphorylation of Proteins in the Outer Mitochondrial Membrane by Protein Kinase C

J. Backer, J. Backer, J. Arcoleo, 1987 .

Imaging Key Biomarkers of Tumor Angiogenesis

Joseph M. Backer, Marina V. Backer, M. Backer, 2012, Theranostics.

Molecular vehicles for targeted drug delivery.

K. Przekop, M. Backer, R. Aloise, 2002, Bioconjugate chemistry.

Overexpression of NM23-1 enhances responsiveness of IMR-32 human neuroblastoma cells to differentiation stimuli.

M. Backer, J. Backer, C. Mendola, 2000, Anticancer research.

Enhanced fluorescence diffuse optical tomography with indocyanine green-encapsulating liposomes targeted to receptors for vascular endothelial growth factor in tumor vasculature

Quing Zhu, Yan Xu, Saeid Zanganeh, 2013, Journal of biomedical optics.

Noninvasive Imaging of Liposomal Delivery of Superparamagnetic Iron Oxide Nanoparticles to Orthotopic Human Breast Tumor in Mice

S. Sarkar, D. Artemov, M. Backer, 2015, Pharmaceutical Research.

scVEGF Microbubble Ultrasound Contrast Agents: A Novel Probe for Ultrasound Molecular Imaging of Tumor Angiogenesis

K. Ley, C. Anderson, A. Klibanov, 2010, Investigative radiology.

Cysteine-containing fusion tag for site-specific conjugation of therapeutic and imaging agents to targeting proteins.

F. Blankenberg, R. Levenson, M. Backer, 2008, Methods in molecular biology.

11A-4 Molecular Imaging with Targeted Contrast Agents and High Frequency Ultrasound

J. Hossack, K. Ley, N. Jong, 2007, 2007 IEEE Ultrasonics Symposium Proceedings.

PET imaging of EGF receptors using [18F]FBEM-EGF in a head and neck squamous cell carcinoma model

Xiaoyuan Chen, G. Niu, J. Backer, 2012, European Journal of Nuclear Medicine and Molecular Imaging.

In Vivo, Dual-Modality OCT/LIF Imaging Using a Novel VEGF Receptor-Targeted NIR Fluorescent Probe in the AOM-Treated Mouse Model

Amy M. Winkler, Jennifer M. Watson, J. Barton, 2011, Molecular Imaging and Biology.

Refolding and characterization of human recombinant heparin-binding neurite-promoting factor.

I. Kovesdi, J. Backer, J. Fairhurst, 1994, Protein expression and purification.

In vivo imaging using a VEGF-based near-infrared fluorescent probe for early cancer diagnosis in the AOM-treated mouse model

Jennifer K. Barton, Joseph M. Backer, Marina V. Backer, 2009, BiOS.

VEGF receptors and neuropilins are expressed in the urothelial and neuronal cells in normal mouse urinary bladder and are upregulated in inflammation.

S. Soker, L. Birder, M. Freeman, 2008, American journal of physiology. Renal physiology.

In vivo tumor angiogenesis imaging with site-specific labeled 99mTc-HYNIC-VEGF

Vimalkumar A. Patel, F. Blankenberg, M. Backer, 2006, European Journal of Nuclear Medicine and Molecular Imaging.

Direct site-specific labeling of the Cys-tag moiety in scVEGF with technetium 99m.

F. Blankenberg, M. Backer, J. Backer, 2008, Bioconjugate chemistry.

Self-assembled "dock and lock" system for linking payloads to targeting proteins.

M. Backer, J. Backer, Brian T Jehning, 2006, Bioconjugate chemistry.

Imaging Key Biomarkers of Tumor Angiogenesis

M. Backer, J. Backer, 2012, Theranostics.

Targeted scVEGF / ( 177 ) Lu radiopharmaceutical inhibits growth of metastases and can be effectively combined with chemotherapy

F. Blankenberg, M. Backer, J. Backer, 2016 .

Nm23‐transfected MDA‐mB‐435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: A 31P nuclear magnetic resonance study in vivo and in vitro

R. Gillies, V. P. Chacko, Z. Bhujwalla, 1999, Magnetic resonance in medicine.

Cysteine-containing fusion tag for site-specific conjugation of therapeutic and imaging agents to targeting proteins.

F. Blankenberg, R. Levenson, M. Backer, 2008, Methods in molecular biology.

Engineering S-protein fragments of bovine ribonuclease A for targeted drug delivery.

M. Backer, R. Aloise, J. Backer, 2002, Protein expression and purification.