M. Garnett

发表

Influence of polymer architecture on the structure of complexes formed by PEG-tertiary amine methacrylate copolymers and phosphorothioate oligonucleotide.

S. Armes, M. Vamvakaki, S. Stolnik, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Polymer chemical structure is a key determinant of physicochemical and colloidal properties of polymer-DNA complexes for gene delivery.

I. R. Hill, S. Davis, S. Stolnik, 2000, Biochimica et biophysica acta.

Fowler, Robyn and Vllasaliu, Driton and Falcone, Franco H. and Garnett, Martin and Smith, Bryan and Horsley, Helen and Alexander, Cameron and Stolnik, Snow (2013) Uptake and transport of B12-conjugated

C. Alexander, M. Garnett, S. Stolnik, 2016 .

Uptake and transport of B12-conjugated nanoparticles in airway epithelium

C. Alexander, M. Garnett, S. Stolnik, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Effect of polymer ionization on the interaction with DNA in nonviral gene delivery systems.

S. Armes, T. Ehtezazi, S. Stolnik, 2003, Biomacromolecules.

Quantification of gastrointestinal liquid volumes and distribution following a 240 mL dose of water in the fasted state.

Martin C Garnett, Luca Marciani, Gordon L Amidon, 2014, Molecular pharmaceutics.

Three-dimensional cerebrospinal fluid flow within the human ventricular system

H. Power, M. Vloeberghs, M. Garnett, 2008, Computer methods in biomechanics and biomedical engineering.

Gene-delivery systems using cationic polymers.

M. Garnett, M C Garnett, 1999, Critical reviews in therapeutic drug carrier systems.

Use of viscoelastic measurements for investigating interparticle interactions in dispersions of micellar-like poly(lactic acid)-poly(ethylene glycol)nanoparticles

S. Davis, T. Tadros, S. Stolnik, 2002 .

Targeted drug conjugates: principles and progress.

M. Garnett, Martin C. Garnett, M. C. Garnett, 2001, Advanced drug delivery reviews.

Physicochemical Evaluation of Nanoparticles Assembled from Poly(lactic acid)−Poly(ethylene glycol) (PLA−PEG) Block Copolymers as Drug Delivery Vehicles

Martin C. Garnett, P. Gellert, S. Davis, 2001 .

Core−Shell Structure of PLA−PEG Nanoparticles Used for Drug Delivery

S. Davis, C. Washington, S. Stolnik, 2003 .

Ligand density and clustering effects on endocytosis of folate modified nanoparticles

M. Garnett, S. Stolnik, D. Vllasaliu, 2012 .

Uptake and metabolism of novel biodegradable poly (glycerol-adipate) nanoparticles in DAOY monolayer.

D. A. Walker, M. Garnett, P. Kallinteri, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Surface Modification of Poly(lactide-co-glycolide) Nanospheres by Biodegradable Poly(lactide)-Poly(ethylene glycol) Copolymers

Allan G. A. Coombes, Martyn C. Davies, Lisbeth Illum, 1994, Pharmaceutical Research.

In vitro cell interaction and in vivo biodistribution of poly(lactide-co-glycolide) nanospheres surface modified by poloxamer and poloxamine copolymers

Martyn C. Davies, Lisbeth Illum, Susan E. Dunn, 1997 .

In vitro displacement by rat serum of adsorbed radiolabeled poloxamer and poloxamine copolymers from model and biodegradable nanospheres.

E. Schacht, S. Davis, E. Kenawy, 1998, Journal of pharmaceutical sciences.

PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug.

S. Davis, S. Stolnik, M. Garnett, 1999, Journal of controlled release : official journal of the Controlled Release Society.

Absorption-promoting effects of chitosan in airway and intestinal cell lines: a comparative study.

L. Casettari, M. Garnett, S. Stolnik, 2012, International journal of pharmaceutics.

Is rat a good model for assessment of particulate-based taste-masked formulations?

C. Roberts, P. Gershkovich, M. Garnett, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Polymeric Nanoparticles for Drug Delivery

M. Garnett, P. Kallinteri, 2007 .

Nanoformulation-by-design: an experimental and molecular dynamics study for polymer coated drug nanoparticles

C. Laughton, C. Alexander, M. Garnett, 2020, RSC advances.

Poly (glycerol adipate) (PGA), an Enzymatically Synthesized Functionalizable Polyester and Versatile Drug Delivery Carrier: A Literature Update

M. Garnett, I. Styliari, Vincenzo Taresco, 2019, Polymers.

Variation in structure and properties of poly(glycerol adipate) via control of chain branching during enzymatic synthesis

C. Alexander, G. Mantovani, M. Garnett, 2016 .

Nanospheres prepared from poly(β-malic acid) benzyl ester copolymers: evidence for their in vitro degradation

M. Davies, S. Davis, M. Vert, 1996 .

Magnetic Resonance Imaging Quantification of Fasted State Colonic Liquid Pockets in Healthy Humans.

L. Marciani, R. Spiller, G. Amidon, 2017, Molecular pharmaceutics.

Novel Poly (glycerol-adipate) Polymers Used for Nanoparticle Making: A Study of Surface Free Energy

M. Garnett, P. Kallinteri, G. Hutcheon, 2008 .

Determination of protection from serum nuclease activity by DNA-polyelectrolyte complexes using an electrophoretic method.

I. R. Hill, S. Davis, M. Garnett, 2001, Analytical biochemistry.

Novel functionalized biodegradable polymers for nanoparticle drug delivery systems.

M. Garnett, P. Kallinteri, G. Hutcheon, 2005, Biomacromolecules.

Evaluation of Poly (Glycerol-Adipate) Nanoparticle Uptake in an In Vitro 3-D Brain Tumor Co-Culture Model

D. A. Walker, M. Garnett, P. Kallinteri, 2007, Experimental biology and medicine.

Development of multicomponent DNA delivery systems based upon poly(amidoamine)-PEG co-polymers.

S. Davis, S. Stolnik, M. Garnett, 2002, Biochimica et biophysica acta.

Delivery of acetogenin-enriched Annona muricata Linn leaf extract by folic acid-conjugated and triphenylphosphonium-conjugated poly(glycerol adipate) nanoparticles to enhance toxicity against ovarian cancer cells.

A. Wongrakpanich, M. Garnett, J. Suksiriworapong, 2022, International journal of pharmaceutics.

Synthesis of nucleoside-boronic esters hydrophobic pro-drugs: A possible route to improve hydrophilic nucleoside drug loading into polymer nanoparticles

W. Irving, G. Mantovani, M. Garnett, 2018, Journal of Drug Delivery Science and Technology.

Penetration and Uptake of Nanoparticles in 3D Tumor Spheroids.

P. Gellert, A. Grabowska, M. Garnett, 2019, Bioconjugate chemistry.

Comparison of Gene Transfection and Cytotoxicity Mechanisms of Linear Poly(amidoamine) and Branched Poly(ethyleneimine) Polyplexes

P. Ferruti, E. Ranucci, M. Garnett, 2018, Pharmaceutical Research.

Abrogation of antibody responses in rats to murine monoclonal antibody 791T/36 by treatment with daunomycin-cis-aconityl-791T/36 conjugates

R. W. Baldwin, M. Garnett, L. Durrant, 2004, Cancer Immunology, Immunotherapy.

Drug incorporation and release of water soluble drugs from novel functionalized poly(glycerol adipate) nanoparticles.

M. Garnett, P. Kallinteri, G. Hutcheon, 2008, Journal of controlled release : official journal of the Controlled Release Society.

Measurement of tumour reactive antibody and antibody conjugate by competition, quantitated by flow cytofluorimetry.

R. W. Baldwin, M. Price, M. Garnett, 1986, Journal of immunological methods.

Increased serum stability and prolonged biological half-life of neocarzinostatin covalently bound to monoclonal antibodies.

M. Garnett, U. Gottschalk, R. Ward, 1991, The Journal of antibiotics.

Multiscale modeling of drug-polymer nanoparticle assembly identifies parameters influencing drug encapsulation efficiency.

C. Laughton, C. Alexander, M. Garnett, 2015, Journal of chemical theory and computation.

Medulloblastoma in childhood: revisiting intrathecal therapy in infants and children

M. Vloeberghs, R. Grundy, S. Conroy, 2010, Cancer Chemotherapy and Pharmacology.

Intermolecular interaction and solid state characterization of abietic acid/chitosan solid dispersions possessing antimicrobial and antioxidant properties

M. Garnett, I. Francolini, A. Piozzi, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Targeting of polyamidoamine-DNA nanoparticles using the Staudinger ligation: attachment of an RGD motif either before or after complexation.

W. Chan, M. Garnett, Susan M. Parkhouse, 2008, Bioorganic & medicinal chemistry.

Fc-mediated transport of nanoparticles across airway epithelial cell layers.

C. Alexander, M. Garnett, S. Stolnik, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Imaging of primary and metastatic colorectal carcinoma with monoclonal antibody 791T/36 and the therapeutic potential of antibody-drug conjugates.

R. W. Baldwin, A. Perkins, J. Hardcastle, 1987, Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc.

Biodistribution of Nanoparticles: Insights from Drug Delivery

M. Garnett, 2007 .

Enhanced nanoparticle uptake into virus infected cells: Could nanoparticles be useful in antiviral therapy?

A. Tarr, W. Irving, R. Urbanowicz, 2018, International journal of pharmaceutics.

Synthesis and properties of a biodegradable polymer-drug conjugate: Methotrexate-poly(glycerol adipate).

M. Garnett, K. Sakchaisri, D. Ivanov, 2018, Colloids and surfaces. B, Biointerfaces.

Preparation and properties of a drug‐carrier‐antibody conjugate showing selective antibody‐directed cytotoxicity in vitro

R. W. Baldwin, M. Garnett, M. Embleton, 1983, International journal of cancer.

Application of biorelevant saliva‐based dissolution for optimisation of orally disintegrating formulations of felodipine

C. Roberts, P. Gershkovich, M. Garnett, 2019, International journal of pharmaceutics.

Studies on the mechanism of action of an antibody-targetted drug-carrier conjugate.

R. W. Baldwin, M. Garnett, M. Embleton, 1985, Anti-cancer drug design.

Endocytosis of immunotoxin-791T/36-RTA by tumor cells in relation to its cytotoxic action.

R. W. Baldwin, M. Price, M. Garnett, 1991, Cancer research.

The assessment of hookworm calreticulin as a potential vaccine for necatoriasis

D. Pritchard, M. Garnett, S. Stolnik, 2005, Parasite immunology.

Poly(lactic acid)−Poly(ethylene oxide) (PLA−PEG) Nanoparticles: NMR Studies of the Central Solidlike PLA Core and the Liquid PEG Corona

P. Gellert, S. Davis, S. Stolnik, 2002 .

Nanomedicines: Delivering Drugs Using Bottom up Nanotechnology

M. Garnett, 2005 .

Developing novel anthelmintics: the stability of cysteine proteinase activity in a supernatant extract of papaya latex

M. Garnett, I. Duce, J. Behnke, 2021, Heliyon.

Polylactide-poly(ethylene Glycol) Micellar-like Particles as Potential Drug Carriers: Production, Colloidal Properties and Biological Performance

P. Gellert, S. Davis, S. Stolnik, 2001, Journal of drug targeting.

COLLOIDAL STABILITY AND DRUG INCORPORATION ASPECTS OF MICELLAR-LIKE PLA-PEG NANOPARTICLES

S. Stolnik, M. Garnett, L. Illum, 1999 .

Properties of acyl modified poly(glycerol‐adipate) comb‐like polymers and their self‐assembly into nanoparticles

C. Alexander, G. Mantovani, M. Garnett, 2016, Journal of polymer science. Part A, Polymer chemistry.

Synthesis of 2'-deoxyuridine and 5-fluoro-2'-deoxyuridine derivatives and evaluation in antibody targeting studies.

R. W. Baldwin, M. Garnett, S. R. Chhabra, 1993, Journal of medicinal chemistry.

Application of Monoclonal Antibody 791T/36 for Radioimmunodetection of Human Tumours and for Targeting Cytotoxic Drugs

R. W. Baldwin, A. Perkins, M. Price, 1984 .

Tight junction modulation by chitosan nanoparticles: comparison with chitosan solution.

Driton Vllasaliu, Lisbeth Illum, Luca Casettari, 2010, International journal of pharmaceutics.

Oral dosing with papaya latex is an effective anthelmintic treatment for sheep infected with Haemonchus contortus

M. Garnett, F. Jackson, D. Bartley, 2011, Parasites & Vectors.

Gene therapy used for tissue engineering applications

K. Shakesheff, S. Howdle, M. Garnett, 2007, The Journal of pharmacy and pharmacology.

Microscopic Investigations into PEG−Cationic Polymer-Induced DNA Condensation

C. Roberts, S. Stolnik, M. Garnett, 2001 .

Polylactide−Poly(ethylene glycol) Copolymers as Drug Delivery Systems. 1. Characterization of Water Dispersible Micelle-Forming Systems

Stephen E. Harding, M. C. Davies, Susan E. Dunn, 1996 .

In vitro co-culture model of medulloblastoma and human neural stem cells for drug delivery assessment.

Cameron Alexander, P. Gellert, C. Alexander, 2015, Journal of biotechnology.

The colloidal properties of surfactant-free biodegradable nanospheres from poly(β-malic acid-co-benzyl malate)s and poly(lactic acid-co-glycolide)

M. Davies, S. Davis, M. Vert, 1995 .

Basement membrane influences intestinal epithelial cell growth and presents a barrier to the movement of macromolecules.

S. Stolnik, M. Garnett, D. Vllasaliu, 2014, Experimental cell research.

In vitro cytotoxicity of poly(amidoamine)s: relevance to DNA delivery.

I. R. Hill, S. Davis, M. Garnett, 1999, Biochimica et biophysica acta.

Epithelial toxicity of alkylglycoside surfactants.

C. Alexander, M. Garnett, S. Stolnik, 2013, Journal of pharmaceutical sciences.

New N-acyl amino acid-functionalized biodegradable polyesters for pharmaceutical and biomedical applications

C. Laughton, C. Alexander, M. Garnett, 2016 .

Facile synthesis of responsive nanoparticles with reversible, tunable and rapid thermal transitions from biocompatible constituents.

C. Alexander, J. Aylott, W. Chan, 2009, Chemical communications.

Evaluation of calcium depletion as a strategy for enhancement of mucosal absorption of macromolecules.

C. Alexander, M. Garnett, S. Stolnik, 2012, Biochemical and biophysical research communications.

Enhanced uptake of nanoparticle drug carriers via a thermoresponsive shell enhances cytotoxicity in a cancer cell line.

Kristofer J. Thurecht, Jonathan W. Aylott, Cameron Alexander, 2013, Biomaterials science.

Thermoresponsive polymer colloids for drug delivery and cancer therapy.

C. Alexander, J. Aylott, W. Chan, 2011, Macromolecular bioscience.

The effect of surface coverage and conformation of poly(ethylene oxide) (PEO) chains of poloxamer 407 on the biological fate of model colloidal drug carriers.

S. Davis, M. Garnett, S. Stolnik, 2001, Biochimica et biophysica acta.

Adsorption behaviour and conformation of selected poly(ethylene oxide) copolymers on the surface of a model colloidal drug carrier

S. Davis, S. Stolnik, M. Garnett, 1997 .

Biodistribution and Therapeutic Efficacy of a Monoclonal Antibody-Methotrexate Conjugate in Mice

R. W. Baldwin, M. Garnett, M. Pimm, 1988 .

Sensitivity of newly established colorectal cell lines to cytotoxic drugs and monoclonal antibody drug conjugates.

R. W. Baldwin, J. Hardcastle, M. Garnett, 1987, British Journal of Cancer.

Development and optimisation of simulated salivary fluid for biorelevant oral cavity dissolution.

C. Roberts, Sally Gittings, P. Gershkovich, 2021, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Biodistribution and tumour localization of a methotrexate‐monoclonal‐antibody 791T/36 conjugate in nude mice with human tumour xenografts

R. W. Baldwin, M. Garnett, M. V. Pimm, 2006, International journal of cancer.

Biodistribution of a monoclonal antibody‐methotrexate conjugate (791T/36‐MTX) in patients with colorectal cancer

R. W. Baldwin, A. Perkins, M. Garnett, 1988, International journal of cancer. Supplement = Journal international du cancer. Supplement.

Biodistribution of methotrexate-monoclonal antibody conjugates and complexes: experimental and clinical studies.

R. W. Baldwin, A. Perkins, M. Garnett, 1987, Cancer treatment reviews.

In Silico Screening for Solid Dispersions: The Trouble with Solubility Parameters and χFH.

C. Laughton, C. Alexander, M. Garnett, 2018, Molecular pharmaceutics.

Multiplexing Spheroid Volume, Resazurin and Acid Phosphatase Viability Assays for High-Throughput Screening of Tumour Spheroids and Stem Cell Neurospheres

Delyan P. Ivanov, Cameron Alexander, Martin C. Garnett, 2014, PloS one.

MicroRNA-Based Drugs for Brain Tumors.

C. Loussouarn, P. Baril, M. Garnett, 2018, Trends in cancer.

Penetration and intracellular uptake of poly(glycerol-adipate) nanoparticles into three-dimensional brain tumour cell culture models

D. A. Walker, M. Garnett, W. Meng, 2016, Experimental biology and medicine.

The relative anthelmintic efficacy of plant-derived cysteine proteinases on intestinal nematodes

M. Garnett, I. Duce, J. Behnke, 2013, Journal of Helminthology.

Antigenicity and drug susceptibility of human osteogenic sarcoma cells "escaping" a cytotoxic methotrexate-albumin-monoclonal antibody conjugate.

R. W. Baldwin, M. Garnett, M. Embleton, 1984, British Journal of Cancer.

Poly (glycerol adipate) (PGA): From a functionalized nano-carrier to a polymeric-prodrug matrix to create amorphous solid dispersions.

M. Garnett, J. Burley, A. Pearce, 2019, Journal of pharmaceutical sciences.

Rapid Nanogram Scale Screening Method of Microarrays to Evaluate Drug-Polymer Blends Using High-Throughput Printing Technology.

D. Scurr, C. Laughton, C. Alexander, 2017, Molecular pharmaceutics.

Defining the drug incorporation properties of PLA-PEG nanoparticles.

T. Ehtezazi, S. Davis, S. Stolnik, 2000, International journal of pharmaceutics.

An improved synthesis of a methotrexate-albumin-791T/36 monoclonal antibody conjugate cytotoxic to human osteogenic sarcoma cell lines.

R. W. Baldwin, M. Garnett, 1986, Cancer research.

Preparation and characterisation of rose Bengal-loaded surface-modified albumin nanoparticles.

E. Schacht, S. Davis, P. Ferruti, 2001, Journal of controlled release : official journal of the Controlled Release Society.

High-throughput miniaturized screening of nanoparticle formation via inkjet printing

M. Alexander, A. Hook, C. Alexander, 2018 .

Nanomedicines and nanotoxicology: some physiological principles.

M. Garnett, P. Kallinteri, M C Garnett, 2006, Occupational medicine.

Polymer nanoparticle as a delivery system for ribavirin: Do nanoparticle avoid uptake by Red Blood Cells?

M. Garnett, Y. Abo-Zeid, 2020 .

Modification of the Copolymers Poloxamer 407 and Poloxamine 908 can Affect the Physical and Biological Properties of Surface Modified Nanospheres

Lisbeth Illum, S. Davis, S. Stolnik, 1998, Pharmaceutical Research.

Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison.

M. Garnett, S. Stolnik, D. Vllasaliu, 2011, Biochemical and biophysical research communications.

The influence of synthetic conditions on the stability of methotrexate-monoclonal antibody conjugates determined by reversed phase high performance liquid chromatography.

R. W. Baldwin, F. Hudecz, M. Garnett, 1992, Biomedical chromatography : BMC.

Self-consistent field modelling of poly(lactic acid)–poly(ethylene glycol) particles

F. Leermakers, S. Davis, S. Stolnik, 2001 .

Mouse IgG2b monoclonal antibody fragmentation. Preparation and purification of Fab, Fc and Fab/c fragments.

R. W. Baldwin, M. Garnett, S. Demignot, 1989, Journal of immunological methods.

Nanoparticle transport in epithelial cells: pathway switching through bioconjugation.

C. Alexander, M. Garnett, S. Stolnik, 2013, Small.

Endocytosis of a monoclonal antibody recognising a cell surface glycoprotein antigen visualised using fluorescent conjugates.

R. W. Baldwin, M. Garnett, 1986, European journal of cell biology.

Unsuitability of monoclonal antibodies to oncogene proteins for anti‐tumour drug‐targeting

M. Garnett, C. Wood, N. Habib, 1986, International Journal of Cancer.

Development of a slow non‐viral DNA release system from PDLLA scaffolds fabricated using a supercritical CO2 technique

K. Shakesheff, S. Howdle, M. Garnett, 2007, Biotechnology and bioengineering.

Screening and Matching Polymers with drugs to Improve Drug Incorporation and Retention in Nanoparticles.

M. Garnett, D. Walker, J. Suksiriworapong, 2020, Molecular pharmaceutics.

Mechanism of Free and Conjugated Neocarzinostatin Activity: Studies on Chromophore and Protein Uptake Using a Transferrin-Neocarzinostatin Conjugate

M. Garnett, F. Schönlau, A. Maibücher, 1997, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Exploring the Enzymatic Degradation of Poly(Glycerol Adipate).

M. Garnett, C. Bosquillon, M. McAllister, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Copolymers of amine methacrylate with poly(ethylene glycol) as vectors for gene therapy.

S. Armes, M. Vamvakaki, S. Stolnik, 2001, Journal of controlled release : official journal of the Controlled Release Society.

The effect of poly(ethylene glycol) molecular architecture on cellular interaction and uptake of DNA complexes.

Martin C Garnett, Philip M Williams, Martyn C Davies, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Characterisation of poly(lactic acid):poly(ethyleneoxide) (PLA:PEG) nanoparticles using the self-consistent theory modelling approach

F. Leermakers, S. Stolnik, M. Garnett, 2003 .

Sterically stabilized self-assembling reversibly cross-linked polyelectrolyte complexes with nucleic acids for environmental and medical applications.

P. Ferruti, E. Ranucci, M. Garnett, 2009, Biochemical Society Transactions.

Long circulating biodegradable poly(phosphazene) nanoparticles surface modified with poly(phosphazene)-poly(ethylene oxide) copolymer.

M C Davies, M. Davies, E. Schacht, 1997, Biomaterials.

Preparation and in vitro characterization of HSA-mPEG nanoparticles.

E. Schacht, S. Davis, M. Garnett, 1999, International journal of pharmaceutics.