J. Chowdhury

发表

Gene therapy as an alternative to liver transplantation

C. Steer, B. Kren, N. Chowdhury, 2002, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

D W Nebert, A Bairoch, J Magdalou, 1997, Pharmacogenetics.

Reconstitution of apoB mRNA editing in liver by gene-transfer as a potential approach for the treatment of severe forms of polygenic hypercholesterolemia--an outline of the rationale.

J. Chowdhury, J. Greeve, 1996, Zeitschrift fur Gastroenterologie.

Replacement of liver function in rats by transplantation of microcarrier-attached hepatocytes.

S. Levenson, N. Chowdhury, J. Chowdhury, 1986, Science.

Therapeutic potential of hepatocyte transplantation.

J. Chowdhury, Sanjeev Gupta, 2002, Seminars in cell & developmental biology.

Transplantation of microcarrier‐attached hepatocytes into 90% partially hepatectomized rats

S. Levenson, J. Chowdhury, A. Demetriou, 1988, Hepatology.

A replication-deficient rSV40 mediates liver-directed gene transfer and a long-term amelioration of jaundice in gunn rats.

D. Strayer, N. Chowdhury, J. Chowdhury, 2000, Gastroenterology.

THE EFFECT OF CD28/B7 BLOCKADE ON ALLOREACTIVE T AND B CELLS AFTER LIVER CELL TRANSPLANTATION 1

B. Reddy, G. Droguett, M. Horwitz, 2001, Transplantation.

Fate of DNA targeted to the liver by asialoglycoprotein receptor-mediated endocytosis in vivo. Prolonged persistence in cytoplasmic vesicles after partial hepatectomy.

C. Wu, N. Chowdhury, J. Chowdhury, 1993, The Journal of biological chemistry.

Genetic inheritance of Gilbert's syndrome

P. Bosma, J. Chowdhury, H. Keino, 1995, The Lancet.

Distribution of UDPglucuronosyltransferase in rat tissue.

P. Novikoff, N. Chowdhury, J. Chowdhury, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Phenolic Antioxidants Induce UDP‐glucuronosyltransferase in Rat Liver a

K. Kashfi, A. Dannenberg, N. Chowdhury, 1995, Annals of the New York Academy of Sciences.

Regulation of uridine diphosphate glucuronosyltransferase expression by phenolic antioxidants.

K. Kashfi, A. Dannenberg, N. Chowdhury, 1994, Cancer Research.

Bile pigment composition and hepatic UDP-glucuronyl transferase activity in the fetal and adult dogfish shark, Squalus acanthias.

N. Chowdhury, J. Chowdhury, I. Arias, 1982, Comparative biochemistry and physiology. B, Comparative biochemistry.

Characterization and Evaluation of Detoxification Functions of a Nontumorigenic Immortalized Porcine Hepatocyte Cell Line (HepLiu1)

J. Chowdhury, A. Rifai, H. Jauregui, 1999, Cell transplantation.

Expression of specific UDP‐glucuronosyltransferase isoforms in carcinogen‐induced preneoplastic rat liver nodules

M. Saber, F. Becker, P. Mackenzie, 1991, Hepatology.

Recombinant adenoassociated virus in cancer gene therapy.

C. Guha, N. Chowdhury, J. Chowdhury, 2000, Journal of hepatology.

Long-term improvement of hypercholesterolemia after ex vivo gene therapy in LDLR-deficient rabbits.

J. Wilson, J. Baker, N. Chowdhury, 1991, Science.

Hepatocyte transplantation: Back to the future

J. Chowdhury, Sanjeev Gupta, 1992 .

Permanent engraftment and function of hepatocytes delivered to the liver: Implications for gene therapy and Liver Repopulation

R. Burk, J. Chowdhury, K. Bhargava, 1991, Hepatology.

Treatment of experimental colitis by oral tolerance induction: a central role for suppressor lymphocytes

N. Chowdhury, J. Chowdhury, S. Ben-Horin, 2000, American Journal of Gastroenterology.

Oral tolerization ameliorates liver disorders associated with chronic graft versus host disease in mice

A. Nagler, M. Pines, O. Pappo, 2000, Hepatology.

Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes.

R. Mulligan, A. Epstein, J. Wilson, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Cell Culture Models and Animal Models of Viral Hepatitis. Part II: Hepatitis C

C. Guha, N. Chowdhury, J. Chowdhury, 2005, Lab Animal.

Oligonucleotide-mediated site-directed gene repair.

C. Steer, B. Kren, N. Chowdhury, 2002, Methods in enzymology.

Human hepatocyte transplantation: gene therapy and more?

S. Strom, N. Chowdhury, J. Chowdhury, 1998, Pediatrics.

Can a guest liver bring the gift of a gene to disarm a hostile host?

C. Guha, J. Chowdhury, 1995, Hepatology.

Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide.

C. Steer, B. Kren, N. Chowdhury, 1999, Proceedings of the National Academy of Sciences of the United States of America.

A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler–Najjar syndrome

S. Lee, S. Ghosh, B. Reddy, 2002, Gene Therapy.

Hepatocyte-directed gene transfer in vivo leads to transient improvement of hypercholesterolemia in low density lipoprotein receptor-deficient rabbits.

J. Wilson, C. Wu, Catherine H. Wu, 1992, The Journal of biological chemistry.

Treatment of liver failure in rats with end‐stage cirrhosis by transplantation of immortalized hepatocytes

Masahiro Ito, J. Chowdhury, I. Fox, 2002, Hepatology.

Treatment of surgically induced acute liver failure by transplantation of conditionally immortalized hepatocytes.

N. Chowdhury, J. Chowdhury, I. Fox, 1997, Transplantation.

Transplantation of conditionally immortalized hepatocytes to treat hepatic encephalopathy

N. Chowdhury, J. Chowdhury, I. Fox, 1996, Hepatology.

Use of Mammalian Liver Cells for Artificial Liver Support

N. Chowdhury, J. Chowdhury, H. Jauregui, 1996 .

Use of mammalian liver cells for artificial liver support.

N. Chowdhury, J. Chowdhury, H. Jauregui, 1996, Cell transplantation.

Retrovirus-mediated transduction of adult hepatocytes.

R. Mulligan, James M. Wilson, P. Novikoff, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Immune tolerance to a defined heterologous antigen after intrasplenic hepatocyte transplantation: implications for gene therapy

R. Burk, J. Chowdhury, Sanjeev Gupta, 1992, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A NOVEL SYSTEM FOR TRANSPLANTATION OF ISOLATED HEPATOCYTES UTILIZING HBsAg‐PRODUCING TRANSGENIC DONOR CELLS192

R. Burk, N. Chowdhury, J. Chowdhury, 1990, Transplantation.

RACT ifferentiation and Transplantation of Human Embryonic Stem ell – Derived Hepatocytes

Ronald J. Wong, S. Strom, J. Platt, 2017 .

Hepatic gene transfer of the catalytic subunit of the apolipoprotein B mRNA editing enzyme results in a reduction of plasma LDL levels in normal and watanabe heritable hyperlipidemic rabbits.

M. Horwitz, N. Chowdhury, J. Chowdhury, 1996, Journal of lipid research.

Microtubular Disruption Prolongs the Expression of Human Bilirubin-uridinediphosphoglucuronate-glucuronosyltransferase-1 Gene Transferred into Gunn Rat Livers (*)

R. M. Hays, Catherine H. Wu, N. Chowdhury, 1996, The Journal of Biological Chemistry.

Dodging cellular customs: Smuggling macromolecules into hepatocytes

J. Chowdhury, S. Basu, 1994, Hepatology.

Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression.

G. Droguett, M. Horwitz, N. Chowdhury, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Durability of transgene expression and vector integration: recombinant SV40-derived gene therapy vectors.

M. Zern, J. Rossi, D. Strayer, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Hepatocyte Transplantation: Development of New Systems for Liver Repopulation and Gene Therapy

J. Wilson, J. Chowdhury, S. Gupta, 1992, Seminars in liver disease.

Glucuronidation and the UDP-glucuronosyltransferases in health and disease.

P. G. Wells, C. Guillemette, P. A. Gregory, 2004, Drug metabolism and disposition: the biological fate of chemicals.

Hepatocyte transplantation

J. Chowdhury, I. Fox, 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Hepatocyte transplantation for the treatment of human disease.

S. Strom, J. Chowdhury, I. Fox, 1999, Seminars in liver disease.

Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation.

S. Strom, K. Dorko, N. Chowdhury, 1998, The New England journal of medicine.

Clinical conference. Crigler-Najjar syndrome (type I) in an adult male.

D. Fink, J. Chowdhury, A. Wolkoff, 1979, Gastroenterology.

Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation.

F D Ledley, J. Chowdhury, F. Ledley, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Studies on the growth inhibitory effect of erythrose on Vibrio cholerae.

J. Chowdhury, A. Datta, 1965, Biochimica et biophysica acta.

Bilirubin diglucuronide formation in intact rats and in isolated Gunn rat liver.

N. Chowdhury, J. Chowdhury, A. Wolkoff, 1982, The Journal of clinical investigation.

Bilirubin Mono‐ and diglucuronide formation by human liver In vitro: Assay by high‐pressure liquid chromatography

N. Chowdhury, J. Chowdhury, I. Arias, 1981, Hepatology.

Purification and partial characterization of rat liver bilirubin glucuronoside glucuronosyltransferase.

N. Chowdhury, J. Chowdhury, I. Arias, 1979, The Journal of biological chemistry.

Bile Pigment Metabolism and Its Disorders

N. Chowdhury, J. Chowdhury, Y. Avsar, 2013 .

Survival, organization, and function of microcarrier-attached hepatocytes transplanted in rats.

S. Levenson, P. Novikoff, N. Chowdhury, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Bilirubin conjugation in the spiny dogfish, Squalus acanthias, the small skate, Raja erinacea and the winter flounder, Pseudopleuronectes americanas

N. Chowdhury, J. Chowdhury, I. Arias, 1980 .

Hepatic conversion of bilirubin monoglucuronide to diglucuronide in uridine diphosphate-glucuronyl transferase-deficient man and rat by bilirubin glucuronoside glucuronosyltransferase.

P. Jansen, J. Chowdhury, A. Daniller, 1978, The Journal of clinical investigation.

Disorders of Bilirubin Metabolism

N. Chowdhury, J. Chowdhury, 2020, The Liver.

Enzymatic conversion of bilirubin monoglucuronide to diglucuronide by rat liver plasma membranes.

P. Jansen, J. Chowdhury, I. Arias, 1977, The Journal of biological chemistry.

New Method of Hepatocyte Transplantation and Extracorporeal Liver Support

S. Levenson, N. Chowdhury, J. Chowdhury, 1986, Annals of surgery.

Liver‐Directed Gene Therapy

C. Guha, N. Chowdhury, J. Chowdhury, 2020 .

Primary linitis plastica of the colon: Report of a case and review of the literature

J. Chowdhury, K. Das, 1975, Diseases of the colon and rectum.

Induction of tolerance to hepatitis B virus: can we 'eat the disease' and live with the virus?

J. Chowdhury, Y. Ilan, 1999, Medical hypotheses.

Depolymerization of hepatocellular microtubules after partial hepatectomy.

R. M. Hays, C. Wu, N. Chowdhury, 1994, Journal of Biological Chemistry.

Liver-directed gene therapy: promises, problems and prospects at the turn of the century.

N. Chowdhury, J. Chowdhury, B. Parashar, 2000, Journal of hepatology.

Long-term reduction of serum bilirubin levels in Gunn rats by retroviral gene transfer in vivo.

P. Bosma, N. Chowdhury, J. Chowdhury, 1998, Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome.

D Lindhout, P. Bosma, B. Oostra, 1995, The New England journal of medicine.

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

G. Siest, D. Lancet, D. Nelson, 1991, DNA and cell biology.

Genetic lesions of bilirubin uridine‐diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing Crigler‐Najjar and Gilbert syndromes: Correlation of genotype to phenotype

S. Ghosh, N. Chowdhury, J. Chowdhury, 2000, Human mutation.

Transplantation of Gunn rats with autologous fibroblasts expressing bilirubin UDP-glucuronosyltransferase: correction of genetic deficiency and tumor formation.

P. Bosma, J. Seppen, N. Chowdhury, 1997, Human gene therapy.

Enhancement of retrovirus-mediated gene transfer to rat liver in vivo by infusion of hepatocyte growth factor and triiodothyronine.

N. Chowdhury, J. Chowdhury, H. Minami, 2000, Journal of hepatology.

Homodimerization of Human Bilirubin-Uridine-diphosphoglucuronate Glucuronosyltransferase-1 (UGT1A1) and Its Functional Implications*

G. Kalpana, S. Ghosh, N. Chowdhury, 2001, The Journal of Biological Chemistry.

Transplantation of conditionally immortalized hepatocytes to treat hepatic encephalopathy.

N. Chowdhury, J. Chowdhury, B. H. Kim, 1996, Hepatology.

Prenatal diagnosis of bilirubin‐UDP‐glucuronosyltransferase deficiency in rats by genomic DNA analysis

N. Chowdhury, J. Chowdhury, I. Arias, 1992, Hepatology.

CHARACTERIZATION AND REGULATION OF RAT LIVER UDP GLUCURONOSYLTRANSFERASES

P. Mackenzie, J. Chowdhury, N. Chowdhury, 1989, Clinical and experimental pharmacology & physiology.

Efficient CNS gene delivery by intravenous injection

E. Marusich, D. Strayer, J. Chowdhury, 2010, Nature Methods.

Hepatocyte Transplantation and Liver-Directed Gene Therapy

C. Guha, S. Ghosh, N. Chowdhury, 2013 .

A long-awaited small animal model for hepatitis C.

C. Guha, J. Chowdhury, 2002, Journal of hepatology.

Symposium Article GLUCURONIDATION AND THE UDP-GLUCURONOSYLTRANSFERASES IN HEALTH AND DISEASE

P. G. Wells, C. Guillemette, P. A. Gregory, 2004 .

Conditional immortalization of gunn rat hepatocytes: An ex vivo model for evaluating methods for bilirubin‐UDP‐glucuronosyltransferase gene transfer

M. Schilsky, N. Chowdhury, J. Chowdhury, 1995, Hepatology.

Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man.

P. Bosma, J. Seppen, P. Jansen, 1994, The Journal of biological chemistry.

Prospects for gene therapy of familial hypercholesterolemia.

J. Wilson, J. Chowdhury, 1990, Molecular biology & medicine.

Discrimination between Crigler-Najjar type I and II by expression of mutant bilirubin uridine diphosphate-glucuronosyltransferase.

P. Bosma, J. Seppen, P. Jansen, 1994, The Journal of clinical investigation.

Substrates and products of purified rat liver bilirubin UDP ‐ glucuronosyltransferase

N. Chowdhury, J. Chowdhury, I. Arias, 1986, Hepatology.

Steroid 3- and 17-OH UDP-glucuronosyltransferase activities in rat and rabbit liver microsomes.

C. Falany, N. Chowdhury, J. Chowdhury, 1983, Drug metabolism and disposition: the biological fate of chemicals.

Oral tolerization to adenoviral proteins permits repeated adenovirus‐mediated gene therapy in rats with pre‐existing immunity to adenoviruses

M. Ott, B. Reddy, G. Droguett, 1998, Hepatology.

Long Term Correction of Bilirubin-UDP-glucuronosyltransferase Deficiency in Gunn Rats by Administration of a Recombinant Adenovirus during the Neonatal Period*

M. Horwitz, N. Chowdhury, J. Chowdhury, 1996, The Journal of Biological Chemistry.

Oral tolerization to adenoviral antigens permits long-term gene expression using recombinant adenoviral vectors.

G. Droguett, M. Horwitz, N. Chowdhury, 1997, The Journal of clinical investigation.

Induction of central tolerance by intrathymic inoculation of adenoviral antigens into the host thymus permits long-term gene therapy in Gunn rats.

M. Horwitz, N. Chowdhury, J. Chowdhury, 1996, The Journal of clinical investigation.

Molecular biology of bilirubin metabolism.

P. Bosma, P. Jansen, J. Chowdhury, 1995, Progress in liver diseases.

Kernicterus in an adult who is heterozygous for Crigler-Najjar syndrome and homozygous for Gilbert-type genetic defect.

N. Chalasani, N. Chowdhury, J. Chowdhury, 1997, Gastroenterology.

Report on rabies in West Bengal.

J. Chowdhury, K. K. Modak, 1983, Journal of the Indian Medical Association.

Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.

P. Bosma, A. Duncan, P. Jansen, 1993, Cytogenetics and cell genetics.

Albumin gene expression is down-regulated by albumin or macromolecule infusion in the rat.

A. Panduro, J. Chowdhury, D. Shafritz, 1992, The Journal of clinical investigation.

Using new gene delivery systems to advance HIV gene therapy

D. Strayer, S. Ghosh, J. Chowdhury, 2003 .

Sequence of exons and the flanking regions of human bilirubin‐UDP‐glucuronosyltransferase gene complex and identification of a genetic mutation in a patient with Crigler‐Najjar syndrome, type I

P. Bosma, M. Hofker, P. Jansen, 1992, Hepatology.

Mechanism of the lack of induction of UDP-glucuronosyltransferase activity in Gunn rats by 3-methylcholanthrene. Identification of a truncated enzyme.

P. Jansen, N. Chowdhury, J. Chowdhury, 1990, The Journal of biological chemistry.

Genetic heterogeneity of Crigler-Najjar syndrome type I: a study of 14 cases.

A. Munnich, N. Chowdhury, J. Chowdhury, 1993, Human genetics.

Bilirubin metabolism: Applied physiology

N. Chowdhury, J. Chowdhury, Xia Wang, 2006 .

Reduced bilirubin UDP-glucuronosyltransferase expression in Gilbert syndrome is caused by a sequence abnormality in the promoter region

P. Bosma, B. Oostra, G. Tytgat, 1996 .

Gunn rat: a model for inherited deficiency of bilirubin glucuronidation.

N. Chowdhury, J. Chowdhury, R. Kondapalli, 1993, Advances in veterinary science and comparative medicine.

Manifestations of Inherited Disorders of Bilirubin Glucuronidation During Infancy and Childhood

N. Chowdhury, J. Chowdhury, Y. Ilan, 1998 .

Bilirubin Metabolism and Hyperbilirubinemia

N. Chowdhury, J. Chowdhury, Y. Ilan, 1998 .

A novel intronic mutation results in the use of a cryptic splice acceptor site within the coding region of UGT1A1, causing Crigler-Najjar syndrome type 1.

S. Ghosh, N. Chowdhury, J. Chowdhury, 2002, Molecular genetics and metabolism.

Mechanisms of inherited deficiencies of multiple UDP‐glucuronosyltransferase isoforms in two patients with Crigler‐Najjar syndrome, type I

P. Bosma, P. Jansen, N. Chowdhury, 1992, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Differential regulation by triiodothyronine of substrate-specific uridinediphosphoglucuronate glucuronosyl transferases in rat liver.

R. Tukey, N. Chowdhury, J. Chowdhury, 1983, Biochimica et biophysica acta.

An unusual foreign body in the urinary bladder.

J. Chowdhury, H. Bhattacharya, S. Biswas, 2010, Journal of the Indian Medical Association.

Conjugation and Excretion of Bilirubin

N. Chowdhury, J. Chowdhury, 1983, Seminars in liver disease.

Interaction of coding region mutations and the Gilbert-type promoter abnormality of the UGT1A1 gene causes moderate degrees of unconjugated hyperbilirubinaemia and may lead to neonatal kernicterus

S. Ghosh, A. Santra, A. Chowdhury, 2001, Journal of medical genetics.

A Nonhuman Primate Model of Gilbert's Syndrome

N. Chowdhury, J. Chowdhury, I. Arias, 1984, Hepatology.

Effects of Nutrition on Unconjugated Plasma Bilirubin Concentrations in Squirrel Monkeys

N. Chowdhury, J. Chowdhury, I. Arias, 1984, Hepatology.

Asian Pacific Association for Study of the Liver (APASL)

M. Alter, M. Hashizume, M. Manns, 2003 .

[23] Dismutation of bilirubin monoglucuronide

J. Chowdhury, I. Arias, 1981 .

What can SV40-derived vectors do for gene therapy?

M. Zern, D. Strayer, J. Chowdhury, 2002, Current opinion in molecular therapeutics.

Uptake of bilirubin glucuronides by isolated rat hepatocytes

L. Theilmann, N. Chowdhury, J. Chowdhury, 1991, Gastroenterologia Japonica.

Long-term correction of genetic defect of liver function in rat by transplantation of liver cells after ultraviolet irradiation.

J. Wilson, N. Chowdhury, J. Chowdhury, 1989, Molecular biology & medicine.

Amelioration of analbuminemia by transplantation of allogeneic hepatocytes in tolerized rats.

A. Fabrega, N. Chowdhury, J. Chowdhury, 1995, Transplantation.

Treatment of experimental colitis through induction of oral tolerance towards colitis-extracted proteins

N. Chowdhury, J. Chowdhury, S. Ben-Horin, 1998 .

A critical role of the liver in inducing oral tolerance to adenoviral vectors for long-term gene therapy

N. Chowdhury, J. Chowdhury, Y. Ilan, 1998 .

Hepatocyte transplantation

J. Roy-Chowdhury, J. Chowdhury, I. Fox, 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Prospects of Liver Cell Transplantation and Liver-directed Gene Therapy

J. Chowdhury, 1999, Seminars in liver disease.

The Human Organic Anion Transport Protein SLC21A6 Is Not Sufficient for Bilirubin Transport*

R. Kim, J. Chowdhury, A. Wolkoff, 2003, Journal of Biological Chemistry.

The role of albumin in the hepatic transport of bilirubin: studies in mutant analbuminemic rats.

Y. Morino, N. Chowdhury, J. Chowdhury, 1985, Journal of biochemistry.

Reversibly immortalized human hepatocytes: An eternal fountain of liver support?

C. Guha, N. Chowdhury, J. Chowdhury, 2000 .

Hepatic conversion of bilirubin monoglucuronide to diglucuronide in uridine diphosphate-glucuronyl transferase-deficient man and rat by bilirubin glucuronoside glucuronosyltransferase.

P. Jansen, J. Chowdhury, A. Daniller, 1978, The Journal of clinical investigation.

GENETIC INHERITANCE OF GILBERT'S SYNDROME. AUTHORS' REPLY

P. Bosma, J. Chowdhury, H. Keino, 1995 .

Modification of hepatic genomic DNA using RNA/DNA oligonucleotides

C. Steer, R. Felsheim, B. Kren, 2002, Gene Therapy.