I. Scheffler

发表

Species-specific and Mutant MWFE Proteins

Erin N. Smith, N. Yadava, P. Potluri, 2002, The Journal of Biological Chemistry.

Targeted integration of a dominant neoR marker into a 2- to 3-Mb human minichromosome and transfer between cells

I. Scheffler, H. C. Au, J. Mascarello, 1999, Cytogenetic and Genome Research.

The role of the 5′ untranslated region (UTR) in glucose‐dependent mRNA decay

I. Scheffler, B. J. de la Cruz, S. Prieto, 2002, Yeast.

Molecular characterization of human minichromosomes with centromere from chromosome 1 in human-hamster hybrid cells

A. Jacquemin-Sablon, I. Scheffler, J. Mascarello, 1989, Somatic cell and molecular genetics.

Cyanide Detoxification by the Cobalamin Precursor Cobinamide

G. Boss, Shunhui Zhuang, R. Pilz, 2006, Experimental biology and medicine.

Studies on the assembly of complex II in yeast mitochondria using chimeric human/yeast genes for the iron-sulfur protein subunit.

M. Saghbini, I. Scheffler, P. L. Broomfield, 1994, Biochemistry.

Disruption of Mitochondrial Function during Apoptosis Is Mediated by Caspase Cleavage of the p75 Subunit of Complex I of the Electron Transport Chain

Mark H Ellisman, Cristina Muñoz-Pinedo, Guy A Perkins, 2004, Cell.

Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense.

F. Robert, R. Evans, G. Barish, 2007, Genes & development.

Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation

Jeffrey W. Smith, E. Ruoslahti, A. Richardson, 2010, Molecular and Cellular Biology.

Steady-state and nuclear run-on analyses of transcription in a temperature-sensitive Chinese hamster cell mutant with a defect in RNA metabolism

I. Scheffler, T. Slezynger, Thelma C. Slezynger, 1988, Somatic cell and molecular genetics.

A century of mitochondrial research: achievements and perspectives.

I. Scheffler, I E Scheffler, 2001, Mitochondrion.

The NDUFA1 gene product (MWFE protein) is essential for activity of complex I in mammalian mitochondria.

A. Matsuno-Yagi, T. Yagi, I. Scheffler, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Thermodynamics of the helix-coil transition of the alternating copolymer of deoxyadenylic acid and deoxythymidylic acid.

J. Sturtevant, I. Scheffler, 1969, Journal of molecular biology.

Ischemia-Reoxygenation Protects Mitochondrial Function and Prevents Apoptotic Cell Deaths Induced by Simulated Combined and Individual Mitochondrial HSP 60 and HSP 10 Expression in Cardiac Myocytes

I. Scheffler, R. Mestril, Ian Y. Lian, 2001 .

The tumor suppressor cybL, a component of the respiratory chain, mediates apoptosis induction.

S. Grimm, I. Scheffler, T. Mund, 2003, Molecular biology of the cell.

Investigations of the potential effects of phosphorylation of the MWFE and ESSS subunits on complex I activity and assembly.

N. Yadava, P. Potluri, I. Scheffler, 2008, The international journal of biochemistry & cell biology.

Molecular genetics of complex I-deficient Chinese hamster cell lines.

N. Yadava, P. Potluri, I. Scheffler, 2004, Biochimica et biophysica acta.

Promoter analysis of the human succinate dehydrogenase iron-protein gene--both nuclear respiratory factors NRF-1 and NRF-2 are required.

I. Scheffler, H. C. Au, 1998, European journal of biochemistry.

Characterization of the human SDHC gene encoding of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria.

I. Scheffler, H. C. Au, J. Mascarello, 1998, Gene.

Cell cycle-dependent regulation of thymidine kinase activity introduced into mouse LMTK- cells by DNA and chromatin-mediated gene transfer.

I. Scheffler, C. Steglich, C. A. Schlosser, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Conditionally lethal mutations in chinese hamster cells. I. Isolation of a temperature‐sensitive line and its investigation by cell cycle studies

G. Buttin, I. Scheffler, 1973, Journal of cellular physiology.

UNIVERSITY OF CALIFORNIA, SAN DIEGO Hedgehog Signaling Regulates KIT Expression in Gastrointestinal Stromal Tumors A Thesis submitted in partial satisfaction of the requirements for the degree Master of Science in Biology by

J. Sicklick, Dong-er Zhang, I. Scheffler, 2013 .

Control of mRNA turnover as a mechanism of glucose repression in Saccharomyces cerevisiae.

I. Scheffler, B. J. de la Cruz, S. Prieto, 1992, The international journal of biochemistry & cell biology.

Characterization of single-copy probe from vicinity of centromere of human chromosome 1

A. Jacquemin-Sablon, I. Scheffler, K. Carine, 1988, Somatic cell and molecular genetics.

Temperature-Sensitive Chinese Hamster Fibroblast Mutant with a Defect in RNA Metabolism

I. Scheffler, E. Wong, 1982, Molecular and cellular biology.

Characterization of the gene encoding the iron-sulfur protein subunit of succinate dehydrogenase from Drosophila melanogaster.

I. Scheffler, H. C. Au, 1994, Gene.

Mitochondrial Electron Transport and Oxidative Phosphorylation

I. Scheffler, 2002 .

Molecular and genetic characterization of an ornithine decarboxylase-deficient Chinese hamster cell line.

R. Pilz, I. Scheffler, C. Steglich, 1990, The Journal of biological chemistry.

Integrity of mitochondria in a mammalian cell mutant defective in mitochondrial protein synthesis

K. Burnett, I. Scheffler, 1981, The Journal of cell biology.

The C-terminus of the succinate dehydrogenase IP peptide of Saccharomyces cerevisiae is significant for assembly of complex II.

M. Saghbini, I. Scheffler, D. M. Schmidt, 1992, Biochemistry.

Structural organization of the gene encoding the human iron-sulfur subunit of succinate dehydrogenase.

M. Saghbini, I. Scheffler, H. C. Au, 1995, Gene.

A Chinese Hamster Mutant Cell Line with a Defect in the Integral Membrane Protein CII-3 of Complex II of the Mitochondrial Electron Transport Chain (*)

I. Scheffler, H. C. Au, P. Meijer, 1995, The Journal of Biological Chemistry.

A respiration-deficient Chinese hamster cell line with a defect in mitochondrial protein synthesis: Rapid turnover of some mitochondrial transcripts

I. Scheffler, H. C. Au, 1997, Somatic cell and molecular genetics.

Mitochondrial disease associated with complex I (NADH-CoQ oxidoreductase) deficiency

I. Scheffler, 2015, Journal of Inherited Metabolic Disease.

Posttranscriptional regulation of ornithine decarboxylase activity

I. Scheffler, L. Dircks, T. Slezynger, 1986, Journal of cellular physiology.

Chinese hamster cells deficient in ornithine decarboxylase activity: Reversion by gene amplification and by azacytidine treatment

I. Scheffler, C. Steglich, A. Grens, 1985, Somatic cell and molecular genetics.

An ornithine decarboxylase-deficient mutant of Chinese hamster ovary cells.

I. Scheffler, C. Steglich, 1982, The Journal of biological chemistry.

Induction of ornithine decarboxylase activity in a temperature-sensitive cell cycle mutant of Chinese hamster cells.

I. Scheffler, F. Landy‐Otsuka, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Structure and Morphology. Integration into the Cell

I. Scheffler, 2007 .

Use of the DNA polymerase chain reaction for homology probing: isolation of partial cDNA or genomic clones encoding the iron-sulfur protein of succinate dehydrogenase from several species.

S. Subramani, S. Gould, I. Scheffler, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Development and Characterization of a Conditional Mitochondrial Complex I Assembly System*

N. Yadava, P. Potluri, I. Scheffler, 2004, Journal of Biological Chemistry.

Enzymic joining of polynucleotides. IV. Formation of a circular deoxyadenylate-deoxythymidylate copolymer.

I. Scheffler, B. Olivera, I. R. Lehman, 1968, Journal of molecular biology.

Temperature‐sensitive Chinese hamster cell mutant with a defect in glycoprotein synthesis: Accumulation of the EGF receptor in the endoplasmic reticulum and the role of the glucose‐regulated protein GRP78

I. Scheffler, J. Feige, G. Keller, 1988, Journal of cellular physiology.

Analysis of the protein glycosylation defect of a temperature‐sensitive cell cycle mutant by the use of mutant cells overexpressing the human epidermal growth factor receptor after transfection of the gene

I. Scheffler, J. Feige, Immo E. Scheffler, 1987, Journal of cellular physiology.

Localization of ornithine decarboxylase in mutant CHO cells that overproduce the enzyme. Differences between the intracellular distribution of monospecific ornithine decarboxylase antibodies and radiolabeled alpha-difluoromethylornithine.

F. Sundler, I. Scheffler, L. Persson, 1984, European journal of cell biology.

Mammalian cells with defective mitochondrial functions: a Chinese hamster mutant cell line lacking succinate dehydrogenase activity

G. Ditta, I. Scheffler, K. Soderberg, 1977, Cell.

A mutant of Chinese hamster ovary cells resistant toα-methyl- andα-difluoromethylornithine

I. Scheffler, Jung H. Choi, I. Scheffler, 1982 .

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II

F. Domann, P. Witting, J. Neuzil, 2008, Oncogene.

Suppression of Tumor Growth In vivo by the Mitocan α-tocopheryl Succinate Requires Respiratory Complex II

R. Moreno-Sánchez, S. Rodríguez-Enríquez, P. Witting, 2009, Clinical Cancer Research.

Selection of ornithine decarboxylase-deficient mutants of Chinese hamster ovary cells.

I. Scheffler, C. Steglich, 1983, Methods in enzymology.

Structure and Morphology

I. Scheffler, 2002 .

Lipid‐saccharide intermediates and glycoprotein biosynthesis in a temperature‐sensitive Chinese hamster cell mutant

I. Scheffler, A. Tenner, 1979, Journal of cellular physiology.

Helix formation by d(TA) oligomers. II. Analysis of the helix-coli transitions of linear and circular oligomers.

R. L. Baldwin, E. Elson, I. Scheffler, 1970, Journal of molecular biology.

Enzyme induction in a temperature‐sensitive cell cycle mutant of chinese hamster fibroblasts

I. Scheffler, F. Landy‐Otsuka, 1980, Journal of cellular physiology.

Helix formation by dAT oligomers. I. Hairpin and straight-chain helices.

R. L. Baldwin, E. Elson, I. Scheffler, 1968, Journal of molecular biology.

Nucleotide sequence of the Chinese hamster ornithine decarboxylase gene.

I. Scheffler, C. Steglich, A. Grens, 1989, Nucleic acids research.

The Human OXPHOS System

I. Scheffler, 2004 .

PKCε Promotes Oncogenic Functions of ATF2 in the Nucleus while Blocking Its Apoptotic Function at Mitochondria

T. Ideker, D. Rimm, H. Kluger, 2012, Cell.

Mitochondria make a come back.

I. Scheffler, I E Scheffler, 2001, Advanced drug delivery reviews.

A novel NDUFA1 mutation leads to a progressive mitochondrial complex I-specific neurodegenerative disease.

D. Wallace, D. Mishmar, E. Ruiz-Pesini, 2009, Molecular genetics and metabolism.

Signaling Pathways from Mitochondria to the Cytoplasm and Nucleus

I. Scheffler, 2010 .

Mitochondrial Dysfunction Impairs Tumor Suppressor p53 Expression/Function*

Nicholas B. Griner, D. J. Jerry, N. Yadava, 2011, The Journal of Biological Chemistry.

Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II

Xiu-fang Wang, J. Neuzil, I. Scheffler, 2007, Journal of bioenergetics and biomembranes.

Enhanced synthesis of the glucose/calcium‐regulated proteins in a hamster cell mutant deficient in transfer of oligosaccharide core to polypeptides

Amy S. Lee, I. Scheffler, Kyu Seong Kim, 1986, Journal of cellular physiology.

Biochemical Genetics of Respiration-Deficient Mutants of Animal Cells

I. Scheffler, 1986 .

Glucose-dependent turnover of the mRNAs encoding succinate dehydrogenase peptides in Saccharomyces cerevisiae: sequence elements in the 5' untranslated region of the Ip mRNA play a dominant role.

M. Saghbini, D. Atencio, I. Scheffler, 1995, Molecular biology of the cell.

Glucose-regulated Turnover of mRNA and the Influence of Poly(A) Tail Length on Half-life*

I. Scheffler, B. J. de la Cruz, S. Prieto, 2000, Journal of Biological Chemistry.

The 5'- and 3'-untranslated regions of ornithine decarboxylase mRNA affect the translational efficiency.

I. Scheffler, A. Grens, 1990, The Journal of biological chemistry.

Molecular genetics of succinate:quinone oxidoreductase in eukaryotes.

I. Scheffler, 1998, Progress in nucleic acid research and molecular biology.

Genetic analysis of glucose regulation in saccharomyces cerevisiae: control of transcription versus mRNA turnover.

I. Scheffler, G. P. Cereghino, 1996, The EMBO journal.

Control of mRNA turnover as a mechanism of glucose repression in Saccharomyces cerevisiae

I. Scheffler, A. Lombardo, G. P. Cereghino, 1992, Molecular and cellular biology.

Chinese hamster cells with a minichromosome containing the centromere region of human chromosome 1

B. Hamkalo, I. Scheffler, K. Carine, 1986, Somatic cell and molecular genetics.

UNIVERSITY OF CALIFORNIA, SAN DIEGO HIV Restriction Factors as TLR Signaling Modulators A thesis submitted in partial satisfaction of the requirements for the degree Master of Science in Biology by

Yejin Kim, I. Scheffler, Manqing Li, 2014 .

A respiration-deficient Chinese hamster cell line with a defect in NADH-coenzyme Q reductase.

M J Bissell, M. Bissell, I. Scheffler, 1976, The Journal of biological chemistry.

Mitochondrial Dysfunction in Genetic Diseases

I. Scheffler, 2003 .

PKC ε regulates ATF 2 availability to alter mitochondrial permeability following genotoxic stress

T. Ideker, D. Rimm, H. Kluger, 2013 .

High throughput gene complementation screening permits identification of a mammalian mitochondrial protein synthesis (ρ(-)) mutant.

V. Procaccio, P. Potluri, I. Scheffler, 2016, Biochimica et biophysica acta.

Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells.

A. Matsuno-Yagi, T. Kitajima-Ihara, T. Yagi, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Helix formation by d(TA) oligomers. 3. Electrostatic effects.

R. L. Baldwin, E. Elson, I. Scheffler, 1970, Journal of molecular biology.

The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase).

N. Yadava, P. Potluri, I. Scheffler, 2004, European journal of biochemistry.

Molecular Genetics of the Mammalian NADH–Ubiquinone Oxidoreductase

N. Yadava, I. Scheffler, 2001, Journal of bioenergetics and biomembranes.

EFFECT OF CHANGING pH UPON THE RATE AND MECHANISM OF DECARBOXYLATION OF SUBSTITUTED ANTHRANILIC ACIDS

I. Scheffler, G. E. Dunn, P. Leggate, 1965 .

Combined and Individual Mitochondrial HSP60 and HSP10 Expression in Cardiac Myocytes Protects Mitochondrial Function and Prevents Apoptotic Cell Deaths Induced by Simulated Ischemia-Reoxygenation

I. Scheffler, R. Mestril, Ian Y. Lian, 2001, Circulation.

Assembling complex I with ACAD9.

I. Scheffler, 2010, Cell metabolism.

Import and orientation of the MWFE protein in mitochondrial NADH-ubiquinone oxidoreductase.

N. Yadava, I. Scheffler, 2004, Mitochondrion.

The gene for the iron sulfur protein of succinate dehydrogenase (SDH-IP) maps to human chromosome 1p35-36.1

I. Scheffler, D. Ream-Robinson, Susanne Leckschat, 1993, Somatic cell and molecular genetics.

Chemical and enzymatic studies of deoxyribonucleic acid covalently linked to Ficoll.

I. Scheffler, C. Richardson, 1972, The Journal of biological chemistry.

Isolation and characterization of HL-60 cells resistant to nitroprusside-induced differentiation.

G. Boss, R. Pilz, I. Scheffler, 1994, The Journal of biological chemistry.

ISOPYCNIC CENTRIFUGATION OF CHROMATIN IN RENOGRAFIN SOLUTIONS

I. Scheffler, R. Chan, 1974, The Journal of cell biology.

Regulation of mammalian ornithine decarboxylase. Studies on the induction of the enzyme by hypotonic stress.

I. Scheffler, L. Persson, E. Lövkvist-Wallström, 1995, European journal of biochemistry.

Basic Molecular Biology of Mitochondrial Replication

I. Scheffler, 2008 .

Mitochondrial Electron Transfer and Oxidative Phosphorylation

I. Scheffler, 2007 .

UKCCCR guidelines for the use of cell lines in cancer research

T. Thangarajah, M. Hattori, N. Saitou, 1999, Cytogenetic and Genome Research.

Correction for Fogal et al., “Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation”

Jeffrey W. Smith, E. Ruoslahti, A. Richardson, 2017, Molecular and Cellular Biology.

Energy metabolism in respiration‐deficient and wild type chinese hamster fibroblasts in culture

I. Scheffler, I. Scheffler, M. Donnelly, 1976, Journal of cellular physiology.

Mapping of the genes of some components of the electron transport chain (complex I) on the X chromosome of mammals

I. Scheffler, C. Day, 1982, Somatic cell genetics.

Mitochondrial Mutations and Disease

I. Scheffler, 2002 .

High throughput gene complementation screening permits identification of a mammalian mitochondrial protein synthesis (ρ(-)) mutant.

V. Procaccio, P. Potluri, I. Scheffler, 2016, Biochimica et biophysica acta.

Integrity of mitochondria in a mammalian cell mutant defective in mitochondrial protein synthesis

K. Burnett, I. Scheffler, 1981, The Journal of cell biology.

Conditional lethal mutants of Chinese hamster cells: Mutants requiring exogenous carbondioxide for growth

I. Scheffler, I. Scheffler, 1974, Journal of cellular physiology.

Glycoprotein synthesis in a temperature‐sensitive Chinese hamster cell cycle mutant

I. Scheffler, A. Tenner, J. Zieg, 1977, Journal of cellular physiology.

A respiration-deficient Chinese hamster cell line with a defect in NADH-coenzyme Q reductase.

M. Bissell, I. Scheffler, L. Defrancesco, 1976, The Journal of biological chemistry.

Conditionally lethal mutations in Chinese hamster cells. Characterization of a cell line with a possible defect in the krebs cycle

I. Scheffler, L. Defrancesco, D. Werntz, 1975, Journal of cellular physiology.

Cloning and characterization of the iron-sulfur subunit gene of succinate dehydrogenase from Saccharomyces cerevisiae.

I. Scheffler, K. Carine, A. Lombardo, 1990, The Journal of biological chemistry.