J. Lasarte

B. Sangro, J. Quiroga, J. Herrero, 2013, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Overcoming T cell dysfunction in acidic pH to enhance adoptive T cell transfer immunotherapy

F. Prósper, Flor Navarro, S. Hervás-Stubbs, 2022, Oncoimmunology.

Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus.

Lieping Chen, J. Prieto, I. Melero, 2005, Vaccine.

Evaluation of a Salmonella Strain Lacking the Secondary Messenger C-di-GMP and RpoS as a Live Oral Vaccine

S. Burgui, C. Gil, C. Solano, 2016, PloS one.

The extradomain a of fibronectin enhances the efficacy of lipopolysaccharide defective Salmonella bacterins as vaccines in mice

V. Garrido, I. Farran, I. Lasa, 2012, Veterinary Research.

Helper cell-independent antitumor activity of potent CD8+ T cell epitope peptide vaccines is dependent upon CD40L

J. Prieto, E. Huarte, J. Lasarte, 2013, Oncoimmunology.

Tumor therapy in mice by using a tumor antigen linked to modulin peptides from Staphylococcus epidermidis.

J. Prieto, C. Leclerc, J. Lasarte, 2010, Vaccine.

T(h)1 but not T(h)0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides.

J. Prieto, J. Lasarte, P. Sarobe, 1999, International immunology.

Abnormal Priming of CD 4 T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E 1 Proteins

J. Prieto, J. Lasarte, P. Sarobe, 2002 .

CAR-T Cells for the Treatment of Lung Cancer

J. Lasarte, G. Kochan, D. Escors, 2022, Life.

Searching for Peptide Inhibitors of T Regulatory Cell Activity by Targeting Specific Domains of FOXP3 Transcription Factor

J. Oyarzábal, A. Pineda-Lucena, J. Lasarte, 2021, Biomedicines.

Regression of colon cancer and induction of antitumor immunity by intratumoral injection of adenovirus expressing interleukin-12

J. Prieto, C. Qian, Xiaoming Xie, 1999, Cancer Gene Therapy.

Potent clinical prognostic and systemic adjuvant therapeutic value of plasma fractalkine in PD-L1/PD-1 blockade immunotherapy for lung cancer

J. Lasarte, L. Montuenga, R. Pio, 2022, medRxiv.

Pre-selection of PD-1+ Tumor-Infiltrating CD8+ T cells improves the efficacy of adoptive T-cell Therapy

Spain, S. Hervás-Stubbs, J. Lasarte, 2018 .

The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes

F. Guillén-Grima, S. Hervás-Stubbs, J. Lasarte, 2020, British Journal of Cancer.

Inhibition of FOXP3/NFAT Interaction Enhances T Cell Function after TCR Stimulation

J. Prieto, J. Oyarzábal, P. Coffer, 2015, The Journal of Immunology.

Immunomodulatory Properties of Carvone Inhalation and Its Effects on Contextual Fear Memory in Mice

O. Rabal, S. Hervás-Stubbs, J. Lasarte, 2018, Front. Immunol..

MRP1-CD28 bi-specific oligonucleotide aptamers: target costimulation to drug-resistant melanoma cancer stem cells

J. Lasarte, N. Casares, S. Inogés, 2016, Oncotarget.

Eradication of large tumors expressing human papillomavirus E7 protein by therapeutic vaccination with E7 fused to the extra domain a from fibronectin

J. Prieto, C. Leclerc, P. Berraondo, 2012, International journal of cancer.

Identification of an antigenic epitope for helper T lymphocytes from carcinoembryonic antigen.

J. Prieto, B. Sangro, E. Huarte, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Characterization of an immunologically conserved epitope from hepatitis C virus E2 glycoprotein recognized by HLA-A2 restricted cytotoxic T lymphocytes.

J. Prieto, E. Huarte, J. Lasarte, 2001, Journal of hepatology.

Enhancing immunogenicity of a CTL epitope from carcinoembryonic antigen by selective amino acid replacements.

J. Prieto, E. Huarte, J. Lasarte, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Vaccine‐induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD‐1 and chronicity

B. Bartosch, F. Cosset, J. Heeney, 2007, Hepatology.

Identification and Characterization of a T-Helper Peptide from Carcinoembryonic Antigen

J. Prieto, J. Lasarte, E. Celis, 2004, Clinical Cancer Research.

Lymphocytes from Carcinoembryonic Antigen Identification of an Antigenic Epitope for Helper T Updated Version

J. Prieto, B. Sangro, E. Huarte, 2002 .

Combination of a TLR4 ligand and anaphylatoxin C5a for the induction of antigen-specific cytotoxic T cell responses.

J. Prieto, C. Leclerc, J. Lasarte, 2012, Vaccine.

TCR-induced FOXP3 expression by CD8+ T cells impairs their anti-tumor activity.

Flor Navarro, S. Hervás-Stubbs, J. Lasarte, 2021, Cancer letters.

Vaccine Efficacy in Mice Regulatory T Cell Activity and Improves A Peptide Inhibitor of FOXP3 Impairs

J. Prieto, J. Lasarte, J. Riezu-Boj, 2010 .

CD4 /CD25 Regulatory Cells Inhibit Activation of Tumor-Primed CD4 T Cells with IFN- -Dependent Antiangiogenic Activity, as well as Long-Lasting Tumor Immunity Elicited by Peptide Vaccination

I. Melero, J. Lasarte, N. Casares, 2003 .

In Vitro and In Vivo Down-Regulation of Regulatory T Cell Activity with a Peptide Inhibitor of TGF- 1

J. Lasarte, J. Riezu-Boj, P. Sarobe, 2008 .

A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine‐induced liver damage

P. Boya, J. Prieto, J. Lasarte, 2003 .

A recombinant adenovirus encoding hepatitis C virus core and E1 proteins protects mice against cytokine-induced liver damage.

P. Boya, J. Prieto, J. Lasarte, 2003, Hepatology.

Inhibition of adjuvant-induced TAM receptors potentiates cancer vaccine immunogenicity and therapeutic efficacy.

J. Berzofsky, D. Stroncek, J. Lasarte, 2020, Cancer letters.

Engineering Anti-myeloma Responses Using Affinity-Enhanced TCR-Engineered T Cells.

B. Paiva, J. S. San Miguel, J. Lasarte, 2015, Cancer cell.

Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10–Secreting Lactococcus lactis in Combination With Low-Dose Anti-CD3 Depends on the Induction of Foxp3-Positive T Cells

C. Mathieu, C. Gysemans, J. Lasarte, 2016, Diabetes.

StimulationEnhances T Cell Function after TCR Inhibition of FOXP3/NFAT Interaction

J. Oyarzábal, P. Coffer, S. Hervás-Stubbs, 2015 .

Relevance of CD6-Mediated Interactions in the Regulation of Peripheral T-Cell Responses and Tolerance

J. Lasarte, P. Engel, N. Casares, 2017, Front. Immunol..

Short-Term Local Expression of a PD-L1 Blocking Antibody from a Self-Replicating RNA Vector Induces Potent Antitumor Responses.

J. Prieto, I. Melero, M. Buñuales, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

Adjuvant combination and antigen targeting as a strategy to induce polyfunctional and high-avidity T-cell responses against poorly immunogenic tumors.

J. Prieto, J. Lasarte, J. Riezu-Boj, 2011, Cancer research.

Therapeutic blockade of Foxp3 in experimental breast cancer models

E. D. Bal de Kier Joffé, J. Lasarte, M. Candolfi, 2017, Breast Cancer Research and Treatment.

Monocyte‐derived dendritic cells from HCV‐infected patients transduced with an adenovirus expressing NS3 are functional when stimulated with the TLR3 ligand poly(I:C)

J. Prieto, J. Lasarte, A. Zabaleta, 2008, Journal of viral hepatitis.

The Extra Domain A from Fibronectin Targets Antigens to TLR4-Expressing Cells and Induces Cytotoxic T Cell Responses In Vivo1

J. Prieto, C. Leclerc, S. Hervás-Stubbs, 2007, The Journal of Immunology.

Identification of CD4+ and CD8+ T cell epitopes of woodchuck hepatitis virus core and surface antigens in BALB/c mice.

J. Prieto, G. González-Aseguinolaza, Á. Vales, 2010, Vaccine.

Engineered promiscuous T helper peptides for the induction of immune responses.

J. Lasarte, A. Zabaleta, P. Sarobe, 2007, Molecular immunology.

Identification of peptide inhibitors of transforming growth factor beta 1 using a phage-displayed peptide library.

J. Prieto, J. Lasarte, J. Riezu-Boj, 2007, Cytokine.

Upregulation of Indoleamine 2,3-Dioxygenase in Hepatitis C Virus Infection

J. Heeney, J. Prieto, T. Wakita, 2007, Journal of Virology.

Immunization against hepatitis C virus with a fusion protein containing the extra domain A from fibronectin and the hepatitis C virus NS3 protein.

J. Prieto, J. Lasarte, J. Riezu-Boj, 2009, Journal of hepatology.

Inhibiting Histone and DNA Methylation Improves Cancer Vaccination in an Experimental Model of Melanoma

F. Prósper, X. Agirre, V. Basso, 2022, Frontiers in Immunology.

T and B cell responses to multivalent prime-boost DNA and viral vectors vaccine combinations against hepatitis C virus in non-human primates

B. Bartosch, F. Cosset, J. Heeney, 2016 .

The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFNγ

J. Prieto, I. Melero, J. Pérez-Gracia, 2007, International journal of cancer.

Epitope spreading driven by the joint action of CART cells and pharmacological STING stimulation counteracts tumor escape via antigen-loss variants

I. Melero, G. González-Aseguinolaza, S. Hervás-Stubbs, 2021, Journal for ImmunoTherapy of Cancer.

Identification of HLA class I-restricted immunogenic neoantigens in triple negative breast cancer

Ibon Tamayo, S. Hervás-Stubbs, J. Lasarte, 2022, Frontiers in Immunology.

Different doses of adenoviral vector expressing IL-12 enhance or depress the immune response to a coadministered antigen: the role of nitric oxide.

J. Prieto, C. Qian, F. Corrales, 1999, Journal of immunology.

Hepatitis C Virus Structural Proteins Impair Dendritic Cell Maturation and Inhibit In Vivo Induction of Cellular Immune Responses

J. Prieto, I. Melero, A. Arina, 2003, Journal of Virology.

Vaccination with an adenoviral vector encoding hepatitis C virus (HCV) NS3 protein protects against infection with HCV-recombinant vaccinia virus.

J. Prieto, Á. Vales, J. Lasarte, 2002, Vaccine.

Targeting the extra domain A of fibronectin for cancer therapy with CAR-T cells

J. San Miguel, F. Prósper, Flor Navarro, 2022, Journal for ImmunoTherapy of Cancer.

Gene expression analysis during acute hepatitis C virus infection associates dendritic cell activation with viral clearance

J. Prieto, G. Missale, J. Lasarte, 2016, Journal of medical virology.

Argentine plant extracts active against polymerase and ribonuclease H activities of HIV‐1 reverse transcriptase

J. Lasarte, M. Cuevas, M. Sanromán, 1999, Phytotherapy research : PTR.

Gemcitabine-mediated depletion of immunosuppressive dendritic cells enhances the efficacy of therapeutic vaccination

Flor Navarro, S. Hervás-Stubbs, J. Lasarte, 2022, Frontiers in Immunology.

The vaccine adjuvant extra domain A from fibronectin retains its proinflammatory properties when expressed in tobacco chloroplasts

I. Farran, J. Lasarte, I. McCarthy-Suárez, 2010, Planta.

FOXP3 expression diversifies the metabolic capacity and enhances the efficacy of CD8 T cells in adoptive immunotherapy of melanoma

S. Hervás-Stubbs, J. Lasarte, N. Casares, 2022, Molecular therapy : the journal of the American Society of Gene Therapy.

Fluoride ion mediated peterson alkenation of bis(trimethylsilyl)methylimines: a novel synthesis of 2-aza-1,3-dienes and N-vinyl-β-lactams

J. Lasarte, J. Aizpurua, C. Palomo, 1989 .

Olfactory Characterization and Training in Older Adults: Protocol Study

J. Lasarte, J. Fernández-Irigoyen, E. Santamaría, 2021, Frontiers in Aging Neuroscience.

Anaphylatoxin C5a Creates a Favorable Microenvironment for Lung Cancer Progression

John D Lambris, J. Lambris, M. Pajares, 2012, The Journal of Immunology.

This information is current as Progression Microenvironment for Lung Cancer Anaphylatoxin C 5 a Creates a Favorable

John D Lambris, J. Lambris, M. Pajares, 2012 .

Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade

S. Vicent, F. Lecanda, J. Pérez-Gracia, 2020, Nature Cancer.

Synthesis and anti-HIV-1 activities of new pyrimido[5,4-b]indoles.

J. Lasarte, F. Borrás, P. Sarobe, 1999, Farmaco.

Synthesis and evaluation of new Reissert analogs as HIV-1 RT inhibitors. 2. Benzo[f]quinoline and pyridine derivatives.

J. Lasarte, F. Borrás, C. San Martín, 1997, Drug design and discovery.

Clinical testing of a dendritic cell targeted therapeutic vaccine in patients with chronic hepatitis C virus infection

J. Prieto, B. Sangro, J. Lasarte, 2015, Molecular therapy. Methods & clinical development.

Dynamic of nasal colonization by methicillin-resistant Staphylococcus aureus ST398 and ST1 after mupirocin treatment in a family in close contact with pigs.

J. Lasarte, C. Torres, E. Gómez-Sanz, 2011, Comparative immunology, microbiology and infectious diseases.

Immune monitoring of immunosuppression withdrawal of liver transplant recipients.

B. Sangro, J. Quiroga, J. Lasarte, 2015, Transplant immunology.

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

F. Marincola, P. Vandenabeele, S. Loi, 2020, Journal for ImmunoTherapy of Cancer.

Poly(Anhydride) Nanoparticles Act as Active Th1 Adjuvants through Toll-Like Receptor Exploitation

J. Irache, C. Gamazo, J. Lasarte, 2010, Clinical and Vaccine Immunology.

Therapeutic vaccination of woodchucks against chronic woodchuck hepatitis virus infection.

J. Prieto, J. Cullen, S. Hervás-Stubbs, 1997, Journal of hepatology.

T-helper cell response to woodchuck hepatitis virus antigens after therapeutic vaccination of chronically-infected animals treated with lamivudine.

J. Prieto, J. Cullen, S. Hervás-Stubbs, 2001, Journal of Hepatology.

Overcoming class II-linked non-responsiveness to hepatitis B vaccine.

J. Prieto, C. Berasain, S. Hervás-Stubbs, 1994, Vaccine.

Induction of cytotoxic T‐cell response against hepatitis C virus structural antigens using a defective recombinant adenovirus

J. Prieto, G. Wilkinson, B. Clarke, 1997, Hepatology.

Abnormal Priming of CD4+ T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E1 Proteins

J. Prieto, J. Lasarte, P. Sarobe, 2002, Journal of Virology.

Short Pc)per Overcoming class II-linked non-responsiveness to hepatitis B vaccine

C. Berasain, J. Lasarte, P. Sarobe, 1994 .

Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses

F. Prósper, G. González-Aseguinolaza, J. Lasarte, 2021, Emerging microbes & infections.

Peptide Inhibitors of Hepatitis C Virus NS3 Protease

M. García-Delgado, J. Vizmanos, J. Lasarte, 2003, Antiviral chemistry & chemotherapy.

A Combined PD-1/C5a Blockade Synergistically Protects against Lung Cancer Growth and Metastasis.

Jackeline Agorreta, Luis M. Montuenga, Teresa Lozano, 2017, Cancer discovery.

Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion

Maite Huarte, C. Kanduri, Ivan Raimondi, 2020, The Journal of cell biology.

CAR density influences antitumoral efficacy of BCMA CAR T cells and correlates with clinical outcome

F. Prósper, M. Juan, B. Paiva, 2021, medRxiv.

PD-1/PD-L1 immune checkpoint and p53 loss facilitate tumor progression in activated B-cell diffuse large B-cell lymphomas.

J. Martinez-Climent, Karen L. Bunting, A. Melnick, 2019, Blood.

Specific and general HLA-DR binding motifs: comparison of algorithms.

E. Huarte, J. Lasarte, J. Riezu-Boj, 2000, Human immunology.

Enhanced anti-tumor efficacy of checkpoint inhibitors in combination with the histone deacetylase inhibitor Belinostat in a murine hepatocellular carcinoma model

V. Trochon-Joseph, B. Sangro, J. Lasarte, 2018, Cancer Immunology, Immunotherapy.

Treatment of Experimental Autoimmune Encephalomyelitis by Sustained Delivery of Low-Dose IFN-α

P. Berraondo, J. Lasarte, N. Casares, 2019, The Journal of Immunology.

Id1 and PD-1 Combined Blockade Impairs Tumor Growth and Survival of KRAS-mutant Lung Cancer by Stimulating PD-L1 Expression and Tumor Infiltrating CD8+ T Cells

S. Vicent, C. Rolfo, J. Lasarte, 2020, Cancers.

Induction of potent and long-lasting CD4 and CD8 T-cell responses against hepatitis C virus by immunization with viral antigens plus poly(I:C) and anti-CD40.

J. Prieto, J. Lasarte, J. Esteban, 2007, Antiviral research.

The Extra Domain A from Fibronectin Targets Antigens to TLR4-Expressing Cells and Induces Cytotoxic T Cell Responses In Vivo1

J. Prieto, C. Leclerc, S. Hervás-Stubbs, 2007, The Journal of Immunology.

Combined immunization with adjuvant molecules poly(I:C) and anti-CD40 plus a tumor antigen has potent prophylactic and therapeutic antitumor effects

J. Prieto, J. Lasarte, A. Zabaleta, 2007, Cancer Immunology, Immunotherapy.

SRC family kinase (SFK) inhibitor dasatinib improves the antitumor activity of anti-PD-1 in NSCLC models by inhibiting Treg cell conversion and proliferation

J. Lasarte, M. Redrado, A. Calvo, 2021, Journal for ImmunoTherapy of Cancer.

Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression

F. Prósper, G. De Velasco, X. Agirre, 2019, Nature Medicine.

Peptide inhibitors of transforming growth factor‐β enhance the efficacy of antitumor immunotherapy

J. Prieto, P. Berraondo, J. Lasarte, 2009, International journal of cancer.

CD137/CD137 Ligand in Tumor and Viral Immunotherapy

I. Melero, I. Tirapu, E. Huarte, 2006 .

[The immunotherapy potential of agonistic anti-CD137 (4-1BB) monoclonal antibodies for malignancies and chronic viral diseases].

J. Prieto, I. Melero, J. Pérez-Gracia, 2006, Anales del sistema sanitario de Navarra.

The TGF-β Pathway: A Pharmacological Target in Hepatocellular Carcinoma?

I. Fabregat, E. Gonzalez-Sanchez, M. Ávila, 2021, Cancers.

Cold-Inducible RNA Binding Protein as a Vaccination Platform to Enhance Immunotherapeutic Responses against Hepatocellular Carcinoma

B. Sangro, J. Lasarte, A. Lujambio, 2020, Cancers.

A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C.

J. Prieto, B. Sangro, I. Melero, 2013, Journal of hepatology.

The Effect of Feeding Glucose Water to Breastfeeding Newborns on Weight, Body Temperature, Blood Glucose, and Breastfeeding Duration

J. Lasarte, J. Martín-Calama, Jose Buftuel, 1997, Journal of human lactation : official journal of International Lactation Consultant Association.

A synthetic peptide from transforming growth factor beta type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury.

J. Prieto, P. Greenwel, I. Castilla-Cortázar, 2003, Cytokine.

Therapeutic effect of a peptide inhibitor of TGF-β on pulmonary fibrosis.

J. Lasarte, J. Riezu-Boj, P. Sarobe, 2011, Cytokine.

In vivo cytotoxic T-lymphocyte induction may take place via CD8 T helper lymphocytes.

J. Prieto, J. Lasarte, P. Sarobe, 1995, Research in immunology.

Simple strategy to induce antibodies of distinct specificity: Application to the mapping of gp120 and inhibition of HIV‐1 infectivity

J. Prieto, C. Berasain, S. Hervás-Stubbs, 1995, European journal of immunology.

Production of interleukin-2 in response to synthetic peptides from hepatitis C virus E1 protein in patients with chronic hepatitis C: relationship with the response to interferon treatment.

J. Prieto, J. Lasarte, M. Civeira, 1996, Journal of hepatology.

Improved dendritic cell‐based immunization against hepatitis C virus using peptide inhibitors of interleukin 10

J. Pawlotsky, J. Prieto, J. Lasarte, 2011, Hepatology.

The Toll like receptor 4 ligand cold-inducible RNA-binding protein as vaccination platform against cancer

José L Carrascosa, Teresa Lozano, Pablo Sarobe, 2017, Oncoimmunology.

Cellular immunity to hepatitis C virus core protein and the response to interferon in patients with chronic hepatitis C

J. Prieto, J. Lasarte, M. Civeira, 1998, Hepatology.

A Peptide Inhibitor of FOXP3 Impairs Regulatory T Cell Activity and Improves Vaccine Efficacy in Mice

J. Prieto, J. Lasarte, J. Riezu-Boj, 2010, The Journal of Immunology.

Polarity of immunogens: implications for vaccine design

J. Lasarte, P. Sarobe, F. Borrás-Cuesta, 1990, European journal of immunology.

T(h)1 but not T(h)0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides.

J. Prieto, J. Lasarte, P. Sarobe, 1999, International immunology.

Targeting the anion exchanger 2 with specific peptides as a new therapeutic approach in B lymphoid neoplasms

J. Martinez-Climent, J. Prieto, O. Rabal, 2017, Haematologica.

Induction of cytotoxic T lymphocytes in mice against the principal neutralizing domain of HIV-1 by immunization with an engineered T-cytotoxic-T-helper synthetic peptide construct.

J. Prieto, J. Lasarte, P. Sarobe, 1992, Cellular immunology.

Searching for the Achilles Heel of FOXP3

J. Lasarte, N. Casares, T. Lozano, 2013, Front. Oncol..

Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs in hematological malignancies

J. Martinez-Climent, F. Prósper, J. Martín-Subero, 2017, Nature Communications.

Enhanced T cell responses against hepatitis C virus by ex vivo targeting of adenoviral particles to dendritic cells

J. Prieto, J. Lasarte, J. Esteban, 2011, Hepatology.

Epigenetic Modifiers: Anti-Neoplastic Drugs With Immunomodulating Potential

F. Prósper, X. Agirre, A. Mondino, 2021, Frontiers in Immunology.

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

P. Pereira, L. Zitvogel, G. Kroemer, 2011, The Journal of experimental medicine.

Intratumoral electroporation of a self-amplifying RNA expressing IL-12 induces antitumor effects in mouse models of cancer

J. Lasarte, C. Smerdou, Noelia Silva-Pilipich, 2022, Molecular therapy. Nucleic acids.

Carcinoembryonic antigen as a target to induce anti-tumor immune responses.

E. Huarte, J. Lasarte, P. Sarobe, 2004, Current cancer drug targets.

Induction of gp120-specific protective immune responses by genetic vaccination with linear polyethylenimine-plasmid complex.

J. Prieto, N. Van Rooijen, G. González-Aseguinolaza, 2005, Vaccine.

CD4+/CD25+ Regulatory Cells Inhibit Activation of Tumor-Primed CD4+ T Cells with IFN-γ-Dependent Antiangiogenic Activity, as well as Long-Lasting Tumor Immunity Elicited by Peptide Vaccination 1

J. Prieto, I. Melero, J. Lasarte, 2003, The Journal of Immunology.

Identification of HLA‐B27–restricted cytotoxic T lymphocyte epitope from carcinoembryonic antigen

J. Prieto, G. Brem, E. Huarte, 2002, International journal of cancer.

Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor

J. Prieto, O. Rabal, J. Oyarzábal, 2017, Oncotarget.

Immunization with a tumor‐associated CTL epitope plus a tumor‐related or unrelated Th1 helper peptide elicits protective CTL immunity

J. Prieto, I. Melero, J. Lasarte, 2001, European journal of immunology.

Enhanced cross-recognition of SARS-CoV-2 Omicron variant by peptide vaccine-induced antibodies

J. Lasarte, M. Esteban, J. García-Arriaza, 2023, Frontiers in Immunology.

A Fusion Protein between Streptavidin and the Endogenous TLR4 Ligand EDA Targets Biotinylated Antigens to Dendritic Cells and Induces T Cell Responses In Vivo

J. Prieto, J. Lasarte, P. Sarobe, 2013, BioMed research international.

Engineering Th determinants for efficient priming of humoral and cytotoxic T cell responses.

J. Prieto, J. Lasarte, P. Sarobe, 2003, International immunology.

Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens

P. Romero, J. Carrascosa, S. Hervás-Stubbs, 2020, Journal for immunotherapy of cancer.

Induction of Multiepitopic and Long‐Lasting Immune Responses Against Tumour Antigens by Immunization with Peptides, DNA and Recombinant Adenoviruses Expressing Minigenes

J. Prieto, E. Huarte, J. Lasarte, 2009, Scandinavian journal of immunology.

Induction of immunosuppressive molecules and regulatory T cells counteracts the antitumor effect of interleukin-12-based gene therapy in a transgenic mouse model of liver cancer.

J. Prieto, P. Berraondo, J. Lasarte, 2007, Journal of hepatology.

Targeting inhibition of Foxp3 by a CD28 2'-Fluro oligonucleotide aptamer conjugated to P60-peptide enhances active cancer immunotherapy.

J. Lasarte, N. Casares, M. M. Soldevilla, 2016, Biomaterials.

Contribution of IL-17-producing gammadelta T cells to the efficacy of anticancer chemotherapy.

P. Pereira, L. Zitvogel, G. Kroemer, 2020 .

Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy

P. Pereira, L. Zitvogel, G. Kroemer, 2011, The Journal of Experimental Medicine.

Vaccine-induced but not tumor-derived Interleukin-10 dictates the efficacy of Interleukin-10 blockade in therapeutic vaccination

J. Lasarte, P. Sarobe, Fernando Aranda, 2016, Oncoimmunology.

Immunity Elicited by Peptide Vaccination Activity, as well as Long-Lasting Tumor -Dependent Antiangiogenic g with IFN-T Cells + Activation of Tumor-Primed CD4 Regulatory Cells Inhibit + /CD25+ CD4

J. Prieto, J. Lasarte, Dotor, 2003 .

Preclinical models for prediction of immunotherapy outcomes and immune evasion mechanisms in genetically heterogeneous multiple myeloma

J. San Miguel, J. Martinez-Climent, F. Prósper, 2023, Nature Medicine.

Genetic Modification of CD8+ T Cells to Express EGFR: Potential Application for Adoptive T Cell Therapies

S. Hervás-Stubbs, J. Lasarte, A. Lujambio, 2019, Frontiers in Immunology.

Identification of small-molecule inhibitors of calcineurin-NFATc signaling that mimic the PxIxIT motif of calcineurin binding partners

Minos-Timotheos Matsoukas, Leonardo Pardo, Teresa Lozano, 2015, Science Signaling.

Is plasma cardiotrophin-1 a marker of hypertensive heart disease?

J. Lasarte, F. Borrás, Arantxa González, 2005, Journal of hypertension.

Local delivery of optimized nanobodies targeting the PD-1/PD-L1 axis with a self-amplifying RNA viral vector induces potent antitumor responses.

J. Lasarte, G. González-Sapienza, Ana Igea, 2023, Cancer letters.

IL-10 expression defines an immunosuppressive dendritic cell population induced by antitumor therapeutic vaccination

S. Hervás-Stubbs, J. Lasarte, E. Guruceaga, 2016, Oncotarget.

Intratumoral STING Agonist Injection Combined with Irreversible Electroporation Delays Tumor Growth in a Model of Hepatocarcinoma

Flor Navarro, J. Lasarte, N. Casares, 2021, BioMed research international.

The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary CD4 T cells

F. Prósper, V. Basso, A. Mondino, 2022, bioRxiv.

Modulation of vaccine-induced immune responses to hepatitis C virus in rhesus macaques by altering priming before adenovirus boosting.

J. Heeney, J. Lasarte, C. Rollier, 2005, The Journal of infectious diseases.

A synthetic peptide from transforming growth factor-beta1 type III receptor prevents myocardial fibrosis in spontaneously hypertensive rats.

J. Lasarte, Arantxa González, P. Sarobe, 2008, Cardiovascular research.

Viremia after one month of interferon therapy predicts treatment outcome in patients with chronic hepatitis C.

J. Prieto, M. Martínez-González, J. Lasarte, 1997, Gastroenterology.

Impact of tumor microenvironment on adoptive T cell transfer activity.

Flor Navarro, S. Hervás-Stubbs, J. Lasarte, 2022, International review of cell and molecular biology.

Improvement of cognitive function in wild-type and Alzheimer´s disease mouse models by the immunomodulatory properties of menthol inhalation or by depletion of T regulatory cells

Flor Navarro, J. Lasarte, J. Fernández-Irigoyen, 2023, Frontiers in Immunology.

Inhibitory effect against polymerase and ribonuclease activities of HIV‐reverse transcriptase of the aqueous leaf extract of Terminalia triflora

J. Lasarte, M. Sanromán, P. López, 2002, Phytotherapy research : PTR.

Abstract 4387: Antiviral and antitumoral effects of the anti-CTLA4 agent tremelimumab in patients with hepatocellular carcinoma (HCC) and chronic hepatitis C virus (HCV) infection: Results from a phase II clinical trial

J. Prieto, B. Sangro, I. Melero, 2012 .

Antigen: the Role of Nitric Oxide Immune Response to a Coadministered Expressing IL-12 Enhance or Depress the Different Doses of Adenoviral Vector

C. Qian, F. Corrales, Xiaoming Xie, 1999 .

The extradomain A of fibronectin (EDA) combined with poly(I:C) enhances the immune response to HIV-1 p24 protein and the protection against recombinant Listeria monocytogenes-Gag infection in the mouse model.

V. Garrido, J. Lasarte, M. Grilló, 2012, Vaccine.

Poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as innate immune system activators.

J. Irache, C. Gamazo, J. Lasarte, 2011, Vaccine.

Induction of antibodies against a peptide hapten does not require covalent linkage between the hapten and a class II presentable T helper peptide

J. Lasarte, M. Civeira, P. Sarobe, 1991, European journal of immunology.

Plasma fractalkine contributes to systemic myeloid diversity and PD‐L1/PD‐1 blockade in lung cancer

J. Lasarte, L. Montuenga, R. Pio, 2023, EMBO reports.

Therapeutic Effect of Irreversible Electroporation in Combination with Poly-ICLC Adjuvant in Preclinical Models of Hepatocellular Carcinoma.

S. Hervás-Stubbs, J. Lasarte, J. Bilbao, 2019, Journal of vascular and interventional radiology : JVIR.

T- and B-cell responses to multivalent prime-boost DNA and viral vectored vaccine combinations against hepatitis C virus in non-human primates

B. Bartosch, F. Cosset, J. Heeney, 2016, Gene Therapy.

Insights on the amino acid side-chain interactions of a synthetic T-cell determinant.

J. Guillaume, J. Lasarte, J. Guillet, 1991, Biologicals : journal of the International Association of Biological Standardization.

B cell epitopes of HIV type 1 p24 capsid protein: a reassessment.

J. Hoebeke, J. Lasarte, P. Sarobe, 1996, AIDS research and human retroviruses.

Induction of neutralizing antibodies against human immunodeficiency virus type 1 using synthetic peptide constructs containing an immunodominant T-helper cell determinant from vpr.

J. Lasarte, P. Sarobe, F. Borrás-Cuesta, 1994, Journal of acquired immune deficiency syndromes.

Hepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection.

B. Sangro, J. Lasarte, E. Larrea, 2011, Journal of hepatology.

Trial of complete weaning from immunosuppression for liver transplant recipients: Factors predictive of tolerance

B. Sangro, J. Quiroga, J. Herrero, 2013, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Regulatory T Cell Inhibition by P60 Combined with Adenoviral AFP Transduced Dendritic Cells for Immunotherapy of Hepatocellular Carcinoma.

H. Matthaei, J. Lasarte, P. Sarobe, 2023, Immunological investigations.

A synthetic peptide from transforming growth factor beta type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury.

P. Greenwel, I. Castilla-Cortázar, J. Lasarte, 2003, Cytokine.

Identification of neoantigen-reactive T cells in hepatocellular carcinoma: implication in adoptive T cell therapy

B. Sangro, Ibon Tamayo, S. Hervás-Stubbs, 2020, Journal of Hepatology.

Enhancement of peptide immunogenicity by insertion of a cathepsin B cleavage site between determinants recognized by B and T cells.

J. Lasarte, E. Larrea, P. Sarobe, 1993, Research in immunology.

Protection against Woodchuck Hepatitis Virus (WHV) Infection by Gene Gun Coimmunization with WHV Core and Interleukin-12

P. Berraondo, R. Garcia-Navarro, B. Blanco-Urgoiti, 2001, Journal of Virology.

Synthesis and evaluation of new Reissert analogs as HIV-1 reverse transcriptase inhibitors. 1. Quinoline and quinoxaline derivatives.

J. Lasarte, F. Borrás, P. Sarobe, 1997, Drug design and discovery.