A. Pavirani

发表

Synthesis of polyallylamine derivatives and their use as gene transfer vectors in vitro.

L. Véron, T. Delair, O. Boussif, 1999, Bioconjugate chemistry.

Effect of liposome-encapsulated clodronate pretreatment on synthetic vector-mediated gene expression in mice

K. Schughart, R. Bischoff, N. Rooijen, 1999, Gene Therapy.

Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

Pascal Barbry, Ronald G. Crystal, R. Crystal, 1991, Nature.

Foetal gene delivery in mice by intra-amniotic administration of retroviral producer cells and adenovirus

A. Douar, C. Coutelle, A. Pavirani, 1997, Gene Therapy.

Therapeutic plasma concentrations of human factor IX in mice after gene delivery into the amniotic cavity: a model for the prenatal treatment of haemophilia B

A. Douar, C. Coutelle, A. Pavirani, 1999, The journal of gene medicine.

Successful expression of β-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the umbilical vein

C. Rodeck, S. Jezzard, C. Coutelle, 1999, Gene Therapy.

Cancer immunotherapy by direct in vivo transfer of immunomodulatory genes.

P. Leroy, P. Erbs, P. Devauchelle, 1998, Research in immunology.

Altered chloride ion channel kinetics associated with the delta F508 cystic fibrosis mutation.

R. Crystal, M. Lazdunski, P. Barbry, 1991, Nature.

Sequence analysis of the canine adenovirus 2 fiber-encoding gene.

M. Mehtali, A. Pavirani, U. Rasmussen, 1995, Gene.

Long‐term humoral and cellular immunity induced by a single immunization with replication‐defective adenovirus recombinant vector

A. Pavirani, J. Guillet, A. Venet, 1995, European journal of immunology.

Phase I study of a recombinant adenovirus-mediated gene transfer in lung cancer patients.

P. Opolon, M. Perricaudet, A. Cesne, 1996, Journal of the National Cancer Institute.

Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells.

M. Perricaudet, R. Crystal, H. Kleinman, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Transient expression of genes transferred in vivo into heart using first-generation adenoviral vectors: role of the immune response.

P. Briand, A. Kahn, D. Duboc, 1995, Human gene therapy.

Adenovirus–mediated in vivo gene transfer and expression in normal rat liver

S. Thorgeirsson, M. Perricaudet, R. Crystal, 1992, Nature Genetics.

Fiberless Recombinant Adenoviruses: Virus Maturation and Infectivity in the Absence of Fiber

D. Spehner, M. Mehtali, A. Pavirani, 1999, Journal of Virology.

Analysis of von Willebrand factor mRNA from the lung of pigs with severe von Willebrand disease by using a human cDNA probe.

A. Pavirani, L. Coulombel, B. Bahnak, 1988, Blood.

Messenger RNA from allotype‐defined rabbits directing the cell‐free synthesis of immunoglobulin heavy and light chains

A. Pavirani, R. Mage, L. Fitzmaurice, 1982, European journal of immunology.

Heterologous protein expression by transimmortalized differentiated liver cell lines derived from transgenic mice (hepatomas/alpha 1 antitrypsin/ONC mouse).

P. Gerlinger, A. Pavirani, F. Perraud, 1990, Biologicals : journal of the International Association of Biological Standardization.

Recombinant Proteins of Therapeutic Interest Expressed by Lymphoid Cell Lines Derived from Transgenic Mice

R. Lathe, R. Crystal, P. Gerlinger, 1989, Nature Biotechnology.

Immune rejection of human dystrophin following intramuscular injections of naked DNA in mdx mice

S. Braun, A. Pavirani, F. Perraud, 2000, Gene Therapy.

Regulation of gap junctional communication by a pro-inflammatory cytokine in cystic fibrosis transmembrane conductance regulator-expressing but not cystic fibrosis airway cells.

S. Suter, M. Chanson, A. Pavirani, 2001, The American journal of pathology.

Characterization of recombinant human factor IX expressed in transgenic mice and in derived trans‐immortalized hepatic cell lines.

A. Balland, T. Faure, A. Pavirani, 1990, The EMBO journal.

Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium.

J. Moss, G. Cutting, C. Chu, 1991, The EMBO journal.

Gene therapy for cystic fibrosis with aerosolized adenovirus-CFTR: characterization of the aerosol and scintigraphic determination of lung deposition in baboons.

P. Diot, A. Pavirani, A. le Pape, 2001, Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine.

Solvoplex: a new type of synthetic vector for intrapulmonary gene delivery.

K. Schughart, R. Bischoff, O. Boussif, 1999, Human gene therapy.

Choosing a Host Cell for Active Recombinant Factor VIII Production Using Vaccinia Virus

J. Cazenave, A. Pavirani, J. Lecocq, 1987, Bio/Technology.

cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization.

J. Pouysségur, G. Pagès, E. Van Obberghen-Schilling, 1991, FEBS letters.

Gene therapy with AdV-IL2 (TG 1021) in unresectable digestive adenocarcinoma. Phase I-II study, first inclusions.

M. Ross, J. Bienvenu, M. Favrot, 1998, Advances in experimental medicine and biology.

Multiple systemic expression of human interferon-β in mice can be achieved upon repeated administration of optimized pcTG90-lipoplex

K. Schughart, A. Pavirani, H. Kolbe, 2000, Gene Therapy.

In vitro and in vivo effects of glucocorticoids on gene transfer to skeletal muscle

K. Schughart, S. Braun, A. Pavirani, 1999, FEBS letters.

Influence of adenoviral fiber mutations on viral encapsidation, infectivity and in vivo tropism

S. Cusack, P. Leissner, M. Mehtali, 2001, Gene Therapy.

Regulation of Adenovirus-Mediated Transgene Expression by the Viral E4 Gene Products: Requirement for E4 ORF3

M. Lusky, M. Mehtali, A. Pavirani, 1999, Journal of Virology.

Down-regulation of cystic fibrosis transmembrane conductance regulator gene expression by agents that modulate intracellular divalent cations

R. Crystal, C. Chu, B. Trapnell, 1992, Molecular and cellular biology.

Humoral immune response to the capsid components of recombinant adenoviruses: Routes of immunization modulate virus‐induced Ig subclass shifts

A. Pavirani, J. Guillet, H. Gahéry-Ségard, 1997, European journal of immunology.

Expression of human α1‐antitrypsin using a recombinant adenovirus vector

M. Perricaudet, A. Pavirani, M. Courtney, 1990 .

Polarity of secretion of alpha 1-antitrypsin by human respiratory epithelial cells after adenoviral transfer of a human alpha 1-antitrypsin cDNA.

M. Perricaudet, R. Crystal, A. Pavirani, 1995, American journal of respiratory cell and molecular biology.

Transgenic Animals as a Source of Genetically-Engineered Trans-Immortalised Cell Lines

A. Balland, T. Faure, A. Pavirani, 1991 .

Gene transfer into canine myoblasts

M. Lusky, M. Mehtali, S. Braun, 1999, Cytotechnology.

Expression of the human cystic fibrosis transmembrane conductance regulator gene in the mouse lung after in vivo intratracheal plasmid-mediated gene transfer.

R. Crystal, E. Scherer, H. Nakamura, 1992, Nucleic acids research.

The cystic fibrosis gene has a "housekeeping"-type promoter and is expressed at low levels in cells of epithelial origin.

R. Crystal, B. Trapnell, H. Nakamura, 1991, The Journal of biological chemistry.

New Engineered Proteins for Use in Therapy and Vaccine Design

M. Kieny, A. Pavirani, J. Lecocq, 1990 .

Differential influence of the E4 adenoviral genes on viral and cellular promoters

P. Leroy, M. Lusky, M. Mehtali, 2000, The journal of gene medicine.

Gene Delivery to Airways

A. Pavirani, C. Schatz, 1998 .

Use of a membrane potential-sensitive probe to assess biological expression of the cystic fibrosis transmembrane conductance regulator.

A. Pavirani, A. Tamanini, E. Nicolis, 1995, Human gene therapy.

Adenoviras‐mediated expression of human CD59 on xenogeneic endothelial cells: Protection against human complement‐mediated lysis and induction of cellular activation by adenoviral transduction

L. Tesson, I. Anegon, A. Pavirani, 1997 .

Cystic fibrosis transmembrane conductance regulator does not affect neutrophil migration across cystic fibrosis airway epithelial monolayers.

S. Suter, M. Chanson, I. Bouchardy, 2000, The American journal of pathology.

Expression of active recombinant human alpha 1-antitrypsin in transgenic rabbits.

R. Bischoff, D. Clesse, L. Houdebine, 1991, Journal of biotechnology.

Adenovirus-mediated gene transfer: influence of transgene, mouse strain and type of immune response on persistence of transgene expression

M. Mehtali, A. Pavirani, A. Michou, 1997, Gene Therapy.

An efficient procedure to select and recover recombinant adenovirus vectors.

M. Mehtali, A. Pavirani, J. Imler, 1995, Gene therapy.

Two independent domains of factor VIII co-expressed using recombinant vaccinia viruses have procoagulant activity.

J. Cazenave, A. Pavirani, J. Lecocq, 1987, Biochemical and biophysical research communications.

Novel cell lines derived from transgenic mice expressing recombinant human proteins

A. Pavirani, F. Perraud, W. Dalemans, 2006, Cytotechnology.

Expression of Recombinant Factor VIII Molecules in Mammalian Cells

T. Faure, A. Pavirani, P. Meulien, 1990 .

Characterization of trans-immortalized hepatic cell lines established from transgenic mice.

T. Faure, A. Pavirani, F. Perraud, 1991, Experimental cell research.

Gene therapy with recombinant adenovirus vectors: evaluation of the host immune response.

M. Lusky, M. Mehtali, A. Pavirani, 1997, Immunology letters.

A 17.6 kbp region located upstream of the rabbit WAP gene directs high level expression of a functional human protein variant in transgenic mouse milk

R. Bischoff, L. Houdebine, A. Pavirani, 1992, FEBS letters.

cDNA cloning and expression of a hamster α‐thrombin receptor coupled to Ca2+ mobilization

J. Pouysségur, G. Pagès, E. Van Obberghen-Schilling, 1991 .

Regenerating cells in human airway surface epithelium represent preferential targets for recombinant adenovirus.

J. Zahm, D. Pierrot, A. Pavirani, 1995, Human gene therapy.

A cystic fibrosis tracheal gland cell line, CF-KM4. Correction by adenovirus-mediated CFTR gene transfer.

M. Merten, C. Figarella, A. Pavirani, 1999, American journal of respiratory cell and molecular biology.

Hydrophobic cluster analysis of G protein-coupled receptors: a powerful tool to derive structural and functional information from 2D-representation of protein sequences.

R. Bischoff, A. Pavirani, U. Rasmussen, 1993, Journal of receptor research.

High level production of human growth hormone in the milk of transgenic mice: the upstream region of the rabbit whey acidic protein (WAP) gene targets transgene expression to the mammary gland

L. Houdebine, A. Pavirani, E. Devinoy, 1994, Transgenic Research.

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

M. Perricaudet, R. Crystal, M. Fukayama, 1992, Cell.

In Vitro and In Vivo Biology of Recombinant Adenovirus Vectors with E1, E1/E2A, or E1/E4 Deleted

M. Lusky, B. Mourot, M. Mehtali, 1998, Journal of Virology.

Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli

M. Mehtali, A. Pavirani, E. Degryse, 1996, Journal of virology.

Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer.

M. Perricaudet, R. Crystal, C. Danel, 1993, The Journal of clinical investigation.

Use of Trypanosoma equiperdum infected rabbits as a source of splenic mRNA; construction of cDNA clones and identification of a rabbit mu heavy chain clone.

A. Pavirani, K. Bernstein, R. Mage, 1983, Molecular immunology.

Selective in vivo transfection of murine biliary epithelia using polycation-enhanced adenovirus

R. Goldin, T. McKay, S. Jezzard, 2000, Gene Therapy.

Targeting cell-specific gene expression with an adenovirus vector containing the lacZ gene under the control of the CFTR promoter.

A. Pavirani, N. Accart, J. Imler, 1996, Gene therapy.

Effects of first generation E1E3-deleted and second generation E1E3E4-deleted/modified adenovirus vectors on human endothelial cell death.

M. Lusky, A. Pavirani, L. Jornot, 2001, Endothelium : journal of endothelial cell research.

Lung gene therapy: in vivo adenovirus-mediated gene transfer to rhesus monkey airway epithelium.

M. Perricaudet, B. Scholte, A. Bout, 1994, Human gene therapy.

Autocrine mitogen IgEGF cooperates with c-myc or with the Hcs locus during hepatocarcinogenesis in transgenic mice.

G. Kay, J. Löhler, A. Pavirani, 1995, Oncogene.

Gene delivery into the central nervous system by nasal instillation in rats.

A. Kahn, A. Pavirani, C. Caillaud, 1995, Gene therapy.

Radioisotopic imaging allows optimization of adenovirus lung deposition for cystic fibrosis gene therapy.

P. Diot, M. Lusky, M. Mehtali, 2001, Human gene therapy.

Aerosol-mediated delivery of recombinant adenovirus to the airways of nonhuman primates.

A. Bout, A. Pavirani, J. Imler, 1995, Human gene therapy.

In vivo adenovirus-mediated transfer of human CFTR cDNA to rhesus monkey airway epithelium: efficacy, toxicity and safety.

M. Perricaudet, A. Bout, A. Pavirani, 1994, Gene therapy.

Tumor necrosis factor modulation of expression of the cystic fibrosis transmembrane conductance regulator gene

R. Crystal, B. Trapnell, K. Yoshimura, 1992, FEBS letters.

Expression of the cystic fibrosis transmembrane conductance regulator gene in cells of non-epithelial origin.

R. Crystal, C. Chu, B. Trapnell, 1991, Nucleic Acids Research.

Trans-complementation of E1-deleted adenovirus: a new vector to reduce the possibility of codissemination of wild-type and recombinant adenoviruses.

M. Mehtali, A. Bout, A. Pavirani, 1995, Human gene therapy.

Differential localization of the cystic fibrosis transmembrane conductance regulator in normal and cystic fibrosis airway epithelium.

A. Pavirani, M. Boutterin, D. Gaillard, 1992, American journal of respiratory cell and molecular biology.

Down-regulation of cystic fibrosis gene mRNA transcript levels and induction of the cystic fibrosis chloride secretory phenotype in epithelial cells by phorbol ester.

C. Chu, B. Trapnell, W. Guggino, 1991, The Journal of biological chemistry.

Conditional repression of the E2 transcription unit in E1-E3-deleted adenovirus vectors is correlated with a strong reduction in viral DNA replication and late gene expression in vitro

M. Mehtali, K. Rittner, A. Pavirani, 1997, Journal of virology.

Localization of the cystic fibrosis transmembrane conductance regulator in airway secretory glands.

A. Pavirani, D. Dreyer, C. Fuchey, 1993, The European respiratory journal.

Immunocytochemical analysis reveals differences between the subcellular localization of normal and delta Phe508 recombinant cystic fibrosis transmembrane conductance regulator.

A. Pavirani, P. Slos, W. Dalemans, 1992, Experimental cell research.

A change in gating mode leading to increased intrinsic Cl‐ channel activity compensates for defective processing in a cystic fibrosis mutant corresponding to a mild form of the disease.

V. Gribkoff, M. Lazdunski, P. Barbry, 1995, EMBO Journal.

Activation of NF-kB mediates ICAM-1 induction in respiratory cells exposed to an adenovirus-derived vector

A. Pavirani, A. Tamanini, E. Nicolis, 2001, Gene Therapy.

Transfection of myoblasts in primary culture with isomeric cationic cholesterol derivatives.

R. Bischoff, S. Braun, A. Pavirani, 1997, Analytical biochemistry.

Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.

J P Lecocq, J. Pouysségur, E. Van Obberghen-Schilling, 1992, Molecular biology of the cell.

Expression of human alpha 1-antitrypsin using a recombinant adenovirus vector.

M. Perricaudet, A. Pavirani, M. Courtney, 1990, FEBS letters.

A peptide ligand of the human thrombin receptor antagonizes alpha-thrombin and partially activates platelets.

J. Pouysségur, E. Van Obberghen-Schilling, E. Obberghen-Schilling, 1993, The Journal of biological chemistry.

Processing and Characterization of Recombinant von Willebrand Factor Expressed in Different Cell Types Using a Vaccinia Virus Vector

A. Pavirani, C. Mazurier, S. Jorieux, 1992, Thrombosis and Haemostasis.

Quantitative detection of CFTR mRNA in gene transfer studies in human, murine and simian respiratory tissues in vitro and in vivo

M. Lusky, A. Pavirani, A. Tamanini, 1999 .

Gene therapy with Adv-IL-2 in unresectable digestive cancer: phase I-II study, intermediate report.

C. Dumontet, C. Lombard-Bohas, J. Bienvenu, 1999, Hepato-gastroenterology.

Fetal somatic gene therapy--a preventive approach to the treatment of genetic disease: the case for.

C. Rodeck, A. Douar, C. Coutelle, 2001, Ernst Schering Research Foundation workshop.

ICAM-1 induction in respiratory cells exposed to a replication-deficient recombinant adenovirus in vitro and in vivo

A. Bout, A. Pavirani, A. Tamanini, 1998, Gene Therapy.

Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: a phase I clinical trial.

G. Bellon, J. Bienvenu, F. Poitevin, 1997, Human gene therapy.

Novel complementation cell lines derived from human lung carcinoma A549 cells support the growth of E1-deleted adenovirus vectors.

T. Faure, M. Mehtali, A. Pavirani, 1996, Gene therapy.

Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.

R. Crystal, B. Trapnell, J. Bargon, 1992, The Journal of biological chemistry.

The therapeutic potential of the human cystic fibrosis transmembrane conductance regulator gene.

A. Pavirani, 1997, Expert opinion on investigational drugs.

intracellular divalent cations. gene expression by agents that modulate transmembrane conductance regulator Down-regulation of cystic fibrosis

B. Trapnell, W. Guggino, A. Pavirani, 2013 .

Construction of a partial rabbit spleen cDNA library and identification of immunoglobulin clones

E. Reddy, A. Pavirani, R. Mage, 1982, European journal of immunology.

Production of recombinant Von Willebrand factor by CHO cells cultured in macroporous microcarriers

T. Faure, A. Pavirani, B. Arbeille, 1990, Cytotechnology.