J. K. Venkatesan

发表

PEO-PPO-PEO micelles as effective rAAV-mediated gene delivery systems to target human mesenchymal stem cells without altering their differentiation potency.

A. Concheiro, C. Alvarez‐Lorenzo, A. Rey-Rico, 2015, Acta biomaterialia.

Biomaterials and Gene Therapy: A Smart Combination for MSC Musculoskeletal Engineering.

J. K. Venkatesan, M. Cucchiarini, B. Mesure, 2019, Current stem cell research & therapy.

Scaffold-Mediated Gene Delivery for Osteochondral Repair

A. Rey-Rico, J. K. Venkatesan, H. Madry, 2020, Pharmaceutics.

Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2019, Journal of clinical medicine.

Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2016, Journal of Experimental Orthopaedics.

Benefits of Recombinant Adeno-Associated Virus (rAAV)-Mediated Insulinlike Growth Factor I (IGF-I) Overexpression for the Long-Term Reconstruction of Human Osteoarthritic Cartilage by Modulation of the IGF-I Axis

D. Kohn, E. Terwilliger, J. K. Venkatesan, 2012, Molecular medicine.

Thermosensitive Hydrogel Based on PEO–PPO–PEO Poloxamers for a Controlled In Situ Release of Recombinant Adeno‐Associated Viral Vectors for Effective Gene Therapy of Cartilage Defects

D. Zurakowski, M. Menger, A. Rey-Rico, 2019, Advanced materials.

rAAV-Mediated sox9 Overexpression Improves the Repair of Osteochondral Defects in a Clinically Relevant Large Animal Model Over Time In Vivo and Reduces Perifocal Osteoarthritic Changes

D. Zurakowski, M. Menger, J. K. Venkatesan, 2021, The American journal of sports medicine.

rAAV-Mediated Overexpression of SOX9 and TGF-β via Carbon Dot-Guided Vector Delivery Enhances the Biological Activities in Human Bone Marrow-Derived Mesenchymal Stromal Cells

A. Rey-Rico, J. K. Venkatesan, G. Schmitt, 2020, Nanomaterials.

Genetic Modification of Human Peripheral Blood Aspirates Using Recombinant Adeno‐Associated Viral Vectors for Articular Cartilage Repair with a Focus on Chondrogenic Transforming Growth Factor‐β Gene Delivery

D. Kohn, A. Rey-Rico, J. K. Venkatesan, 2016, Stem cells translational medicine.

rAAV Vectors as Safe and Efficient Tools for the Stable Delivery of Genes to Primary Human Chondrosarcoma Cells In Vitro and In Situ

D. Kohn, J. K. Venkatesan, G. Schmitt, 2012, Sarcoma.

Effects of rAAV-mediated overexpression of bone morphogenetic protein 3 (BMP-3) on the chondrogenic fate of human bone marrow-derived mesenchymal stromal cells.

J. K. Venkatesan, G. Schmitt, H. Madry, 2022, Human gene therapy.

Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2017, Journal of Experimental Orthopaedics.

rAAV-mediated overexpression of sox9, TGF-β and IGF-I in minipig bone marrow aspirates to enhance the chondrogenic processes for cartilage repair

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2015, Gene Therapy.

Chondrogenic Differentiation Processes in Human Bone Marrow Aspirates upon rAAV-Mediated Gene Transfer and Overexpression of the Insulin-Like Growth Factor I.

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2015, Tissue engineering. Part A.

Determination of effective rAAV-mediated gene transfer conditions to support chondrogenic differentiation processes in human primary bone marrow aspirates

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2014, Gene Therapy.

Effective and durable genetic modification of human mesenchymal stem cells via controlled release of rAAV vectors from self-assembling peptide hydrogels with a maintained differentiation potency.

A. Mata, C. Semino, Amália Monge-Marcet, 2015, Acta biomaterialia.

Biomaterial-Guided Recombinant Adeno-associated Virus Delivery from Poly(Sodium Styrene Sulfonate)-Grafted Poly(ɛ-Caprolactone) Films to Target Human Bone Marrow Aspirates

V. Migonney, J. K. Venkatesan, M. Cucchiarini, 2020 .

Enhanced Chondrogenic Differentiation Activities in Human Bone Marrow Aspirates via sox9 Overexpression Mediated by pNaSS-Grafted PCL Film-Guided rAAV Gene Transfer

V. Migonney, A. Rey-Rico, J. K. Venkatesan, 2020, Pharmaceutics.

Biomaterial-Guided rAAV Delivery from pNaSS-Grafted PCL Films to Target Human Bone Marrow Aspirates.

V. Migonney, J. K. Venkatesan, M. Cucchiarini, 2020, Tissue engineering. Part A.

Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(ɛ-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer.

F. Guilak, F. T. Moutos, A. Rey-Rico, 2018, Human gene therapy.

Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment

M. Alini, D. Eglin, A. Rey-Rico, 2018, International journal of molecular sciences.

Influence of insulin-like growth factor I overexpression via recombinant adeno-associated vector gene transfer upon the biological activities and differentiation potential of human bone marrow-derived mesenchymal stem cells

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2014, Stem Cell Research & Therapy.

Determination of the chondrogenic differentiation processes in human bone marrow-derived mesenchymal stem cells genetically modified to overexpress transforming growth factor-β via recombinant adeno-associated viral vectors.

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2014, Human gene therapy.

Loss of spatial organization and destruction of the pericellular matrix in early osteoarthritis in vivo and in a novel in vitro methodology.

A. Grodzinsky, K. Schenke-Layland, J. K. Venkatesan, 2016, Osteoarthritis and cartilage.

Advanced Gene Therapy Strategies for the Repair of ACL Injuries

Wei Liu, V. Migonney, J. K. Venkatesan, 2022, International journal of molecular sciences.

Controlled Release of rAAV Vectors from APMA-Functionalized Contact Lenses for Corneal Gene Therapy

A. Concheiro, C. Alvarez‐Lorenzo, A. Rey-Rico, 2020, Pharmaceutics.

Advances in Human Mitochondria-Based Therapies

J. K. Venkatesan, H. Madry, M. Cucchiarini, 2022, International journal of molecular sciences.

Potential Gene Therapy Options for Early OA

J. K. Venkatesan, H. Madry, M. Cucchiarini, 2021, Early Osteoarthritis.

Is Extracellular Vesicle-Based Therapy the Next Answer for Cartilage Regeneration?

J. K. Venkatesan, H. Madry, M. Cucchiarini, 2021, Frontiers in Bioengineering and Biotechnology.

Cyclodextrin Cationic Polymer-Based Nanoassemblies to Manage Inflammation by Intra-Articular Delivery Strategies

C. Alvarez‐Lorenzo, A. Mazzaglia, J. K. Venkatesan, 2020, Nanomaterials.

rAAV-Mediated Human FGF-2 Gene Therapy Enhances Osteochondral Repair in a Clinically Relevant Large Animal Model Over Time In Vivo

D. Zurakowski, M. Menger, J. K. Venkatesan, 2021, The American journal of sports medicine.

Current progress in stem cell-based gene therapy for articular cartilage repair.

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2015, Current stem cell research & therapy.

Current perspectives in stem cell research for knee cartilage repair

A. Rey-Rico, J. K. Venkatesan, H. Madry, 2014, Stem cells and cloning : advances and applications.

Human mesenchymal stem cells overexpressing therapeutic genes: from basic science to clinical applications for articular cartilage repair.

J. K. Venkatesan, G. Schmitt, H. Madry, 2012, Bio-medical materials and engineering.

Intra-articular injection of rAAV-hFGF-2 ameliorates monosodium iodoacetate-induced osteoarthritis in rats via inhibiting TLR-4 signaling and activating TIMP-1.

J. K. Venkatesan, H. Madry, M. Cucchiarini, 2022, Toxicology and applied pharmacology.

Effects of TGF-β Overexpression via rAAV Gene Transfer on the Early Repair Processes in an Osteochondral Defect Model in Minipigs

D. Zurakowski, M. Menger, J. K. Venkatesan, 2018, The American journal of sports medicine.

Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2016, Stem Cell Research & Therapy.

Transforming growth factor Beta-releasing scaffolds for cartilage tissue engineering.

A. Rey-Rico, J. K. Venkatesan, H. Madry, 2014, Tissue engineering. Part B, Reviews.

SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells

D. Kohn, J. K. Venkatesan, G. Schmitt, 2012, Stem Cell Research & Therapy.

Translational applications of photopolymerizable hydrogels for cartilage repair

J. K. Venkatesan, H. Madry, M. Cucchiarini, 2019, Journal of experimental orthopaedics.

Hydrogel‐Guided, rAAV‐Mediated IGF‐I Overexpression Enables Long‐Term Cartilage Repair and Protection against Perifocal Osteoarthritis in a Large‐Animal Full‐Thickness Chondral Defect Model at One Year In Vivo

D. Zurakowski, M. Menger, A. Rey-Rico, 2021, Advanced materials.

Current Trends in Viral Gene Therapy for Human Orthopaedic Regenerative Medicine

A. Rey-Rico, J. K. Venkatesan, M. Cucchiarini, 2019, Tissue Engineering and Regenerative Medicine.

rAAV-mediated overexpression of TGF-β stably restructures human osteoarthritic articular cartilage in situ

A. Rey-Rico, J. K. Venkatesan, G. Schmitt, 2013, Journal of Translational Medicine.

rAAV‐mediated combined gene transfer and overexpression of TGF‐β and SOX9 remodels human osteoarthritic articular cartilage

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2016, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Controlled release of gene therapy constructs from solid scaffolds for therapeutic applications in orthopedics.

V. Migonney, J. K. Venkatesan, M. Cucchiarini, 2018, Discovery medicine.

rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

A. Concheiro, C. Alvarez‐Lorenzo, A. Rey-Rico, 2017, International journal of nanomedicine.

Analysis of early cellular responses of anterior cruciate ligament fibroblasts seeded on different molecular weight polycaprolactone films functionalized by a bioactive poly(sodium styrene sulfonate) polymer.

D. Castner, V. Migonney, J. K. Venkatesan, 2019, Biointerphases.

Nicotinamide Adenine Dinucleotide-Dependent Binding of the Neuronal Ca2+ Sensor Protein GCAP2 to Photoreceptor Synaptic Ribbons

C. Sung, F. Schmitz, J. K. Venkatesan, 2010, The Journal of Neuroscience.

Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2017, Journal of Experimental Orthopaedics.

Peripheral blood aspirates overexpressing IGF‐I via rAAV gene transfer undergo enhanced chondrogenic differentiation processes

D. Kohn, A. Rey-Rico, J. K. Venkatesan, 2017, Journal of cellular and molecular medicine.

TGF‐β gene transfer and overexpression via rAAV vectors stimulates chondrogenic events in human bone marrow aspirates

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2016, Journal of cellular and molecular medicine.

EF hand-mediated Ca2+- and cGMP-signaling in photoreceptor synaptic terminals

F. Schmitz, J. K. Venkatesan, C. Grabner, 2012, Front. Mol. Neurosci..

Cytotoxic effects of different mouthwash solutions on primary human articular chondrocytes and normal human articular cartilage - an in vitro study.

J. K. Venkatesan, G. Schmitt, M. Hannig, 2023, Clinical oral investigations.

Antimicrobial mouthwashes as a preventive measure against Covid-19 - a comparative analysis of their effects on human chondrocytes and cartilage (preprint)

J. K. Venkatesan, G. Schmitt, M. Hannig, 2023 .

Enhanced chondrogenic differentiation of human osteoarthritic bone marrow aspirates modified to overexpress the transcription factor sox9 via rAAV-mediated gene transfer in dynamic versus static culture conditions

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2015 .

Co-overexpression of TGF-β and SOX9 via rAAV gene transfer modulates the metabolic and chondrogenic activities of human bone marrow-derived mesenchymal stem cells

A. Rey-Rico, J. K. Venkatesan, J. Frisch, 2016, Stem Cell Research & Therapy.

Adapted chondrogenic differentiation of human mesenchymal stem cells via controlled release of TGF-β1 from poly(ethylene oxide)-terephtalate/poly(butylene terepthalate) multiblock scaffolds.

L. Moroni, J. Sohier, A. Rey-Rico, 2015, Journal of biomedical materials research. Part A.

rAAV TGF-β and FGF-2 Overexpression via pNaSS-Grafted PCL Films Stimulates the Reparative Activities of Human ACL Fibroblasts

V. Migonney, Wei Liu, J. K. Venkatesan, 2023, International journal of molecular sciences.

Current perspectives in stem cell research for knee cartilage repair

A. Rey-Rico, J. K. Venkatesan, H. Madry, 2014, Stem cells and cloning : advances and applications.

Remodeling of Human Osteochondral Defects via rAAV-Mediated Co-Overexpression of TGF-β and IGF-I from Implanted Human Bone Marrow-Derived Mesenchymal Stromal Cells

A. Rey-Rico, J. K. Venkatesan, G. Schmitt, 2019, Journal of clinical medicine.

Overexpression of human DKK 1 via rAAV vector-mediated gene transfer stimulates chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells

J. K. Venkatesan, G. Schmitt, M. Cucchiarini, 2018 .

Current perspectives in stem cell research for knee cartilage repair.

A. Rey-Rico, J. K. Venkatesan, H. Madry, 2014, Stem cells and cloning : advances and applications.

Nicotinamide Adenine Dinucleotide-Dependent Binding of the Neuronal Ca2+ Sensor Protein GCAP2 to Photoreceptor Synaptic Ribbons

C. Sung, F. Schmitz, J. K. Venkatesan, 2010 .

Effects of rAAV-Mediated Overexpression of sox9 and TGF-ß via Alginate Hydrogel-Guided Vector Delivery on the Chondroreparative Activities of Human Bone Marrow-Derived Mesenchymal Stromal Cells

Wei Liu, J. K. Venkatesan, G. Schmitt, 2023, Journal of Tissue Engineering and Regenerative Medicine.

Therapeutic Effects of rAAV-Mediated Concomittant Gene Transfer and Overexpression of TGF-β and IGF-I on the Chondrogenesis of Human Bone-Marrow-Derived Mesenchymal Stem Cells

A. Rey-Rico, J. K. Venkatesan, G. Schmitt, 2019, International Journal of Molecular Sciences.

In vivo rAAV-mediated human TGF-β overexpression reduces perifocal osteoarthritis and improves osteochondral repair in a large animal model at one year.

D. Zurakowski, M. Menger, J. K. Venkatesan, 2022, Osteoarthritis and cartilage.