A. Srivastava

发表

Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses.

B. Sack, G. Jayandharan, L. Zhong, 2010, Human gene therapy.

Role of cellular FKBP52 protein in intracellular trafficking of recombinant adeno-associated virus 2 vectors.

W. Shou, S. Larsen, L. Zhong, 2006, Virology.

Self-complementary adeno-associated virus 2 (AAV)-T cell protein tyrosine phosphatase vectors as helper viruses to improve transduction efficiency of conventional single-stranded AAV vectors in vitro and in vivo.

L. Zhong, A. Srivastava, Linyuan Chen, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

Impaired nuclear transport and uncoating limit recombinant adeno-associated virus 2 vector-mediated transduction of primary murine hematopoietic cells.

W. Shou, S. Larsen, J. Hansen, 2004, Human gene therapy.

Selective in vivo targeting of human liver tumors by optimized AAV3 vectors in a murine xenograft model.

G. Gao, L. Zhong, A. Srivastava, 2014, Human gene therapy.

Two decades of clinical gene therapy--success is finally mounting.

R. Herzog, A. Srivastava, O. Cao, 2010, Discovery medicine.

High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors.

L. Govindasamy, M. Agbandje-McKenna, S. Zolotukhin, 2012, Vaccine.

Recombinant self-complementary adeno-associated virus serotype vector-mediated hematopoietic stem cell transduction and lineage-restricted, long-term transgene expression in a murine serial bone marrow transplantation model.

L. Zhong, A. Srivastava, M. Yoder, 2008, Human gene therapy.

Adeno‐associated virus‐mediated gene transfer

A. Srivastava, A. Srivastava, A. Srivastava, 2008, Journal of cellular biochemistry.

Activation of the NF-κB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy

G. Jayandharan, R. Herzog, A. Srivastava, 2011, Proceedings of the National Academy of Sciences.

α5β1 integrin as a cellular coreceptor for human parvovirus B19: requirement of functional activation of β1 integrin for viral entry

A. Srivastava, K. A. Weigel-Kelley, M. Yoder, 2003 .

Development of optimized AAV3 serotype vectors: Mechanism of high-efficiency transduction of human liver cancer cells

Morag Park, P. Stacpoole, A. Srivastava, 2011, Gene Therapy.

A dual role of EGFR protein tyrosine kinase signaling in ubiquitination of AAV2 capsids and viral second-strand DNA synthesis.

L. Govindasamy, M. Agbandje-McKenna, S. Zolotukhin, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Microglia-specific targeting by novel capsid-modified AAV6 vectors

T. Golde, P. Cruz, Paramita Chakrabarty, 2016, Molecular therapy. Methods & clinical development.

Optimization of the Capsid of Recombinant Adeno-Associated Virus 2 (AAV2) Vectors: The Final Threshold?

L. Govindasamy, M. Agbandje-McKenna, Liujiang Song, 2013, PloS one.

Pyruvate Dehydrogenase Complex Deficiency Caused by Ubiquitination and Proteasome-mediated Degradation of the E1β Subunit*

P. Stacpoole, L. Zhong, A. Srivastava, 2008, Journal of Biological Chemistry.

Kinetic and equilibrium modeling for removal of nitrate from aqueous solutions and drinking water by a potential adsorbent, hydrous bismuth oxide

Y. Sharma, Sushmita Banerjee, A. Srivastava, 2015 .

Working group report: the roles of glycans in hemostasis, inflammation and vascular biology.

R. Cummings, G. Hart, A. Varki, 2008, Glycobiology.

Reprogramming adipose tissue-derived mesenchymal stem cells into pluripotent stem cells by a mutant adeno-associated viral vector.

T. Conlon, N. Terada, A. Srivastava, 2014, Human gene therapy methods.

Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.

T. Flotte, C. Mueller, D. Greiner, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

Evaluation of primitive murine hematopoietic stem and progenitor cell transduction in vitro and in vivo by recombinant adeno-associated virus vector serotypes 1 through 5.

L. Zhong, Baozheng Li, A. Srivastava, 2006, Human gene therapy.

Hematopoietic stem cell transduction by recombinant adeno-associated virus vectors: problems and solutions.

A. Srivastava, A. Srivastava, 2005, Human gene therapy.

Adeno-Associated Virus Type 2-Mediated Gene Transfer: Role of Cellular T-Cell Protein Tyrosine Phosphatase in Transgene Expression in Established Cell Lines In Vitro and Transgenic Mice In Vivo

J. Hansen, L. Zhong, A. Srivastava, 2003, Journal of Virology.

A combined therapeutic approach for pyruvate dehydrogenase deficiency using self-complementary adeno-associated virus serotype-specific vectors and dichloroacetate.

P. Stacpoole, L. Zhong, A. Srivastava, 2008, Molecular genetics and metabolism.

Biochemical and antitumor activity of trimidox, a new inhibitor of ribonucleotide reductase

T. Szekeres, A. Srivastava, M. Fritzer, 2004, Cancer Chemotherapy and Pharmacology.

Development of a Clinical Candidate AAV3 Vector for Gene Therapy of Hemophilia B.

R. Herzog, A. Srivastava, H. Spencer, 2020, Human gene therapy.

Site-Directed Mutagenesis Improves the Transduction Efficiency of Capsid Library-Derived Recombinant AAV Vectors

M. Agbandje-McKenna, Chenghui Yu, A. Srivastava, 2020, Molecular therapy. Methods & clinical development.

Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models

S. Zolotukhin, R. Herzog, A. Srivastava, 2017, Journal of Translational Medicine.

Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 Vectors.

W. Hauswirth, S. Boye, F. Kaye, 2017, Human gene therapy methods.

Strategies to generate high-titer, high-potency recombinant AAV3 serotype vectors

A. Srivastava, G. Aslanidi, C. Ling, 2016, Molecular therapy. Methods & clinical development.

Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma?

W. Hauswirth, T. Flotte, B. Byrne, 2015, Human gene therapy.

Transduction of Primary Human Hepatocytes In Vitro and in Humanized Murine Livers In Vivo by Recombinant AAV3 Vectors

Yuan Wang, G. Gao, L. Zhong, 2014 .

High-Efficiency Transduction of Liver Cancer Cells by Recombinant Adeno-Associated Virus Serotype 3 Vectors

Baozheng Li, A. Srivastava, G. Aslanidi, 2011, Journal of visualized experiments : JoVE.

Development of Novel Recombinant AAV Vectors and Strategies for the Potential Gene Therapy of Hemophilia.

S. Zolotukhin, G. Jayandharan, L. Zhong, 2012, Journal of genetic syndromes & gene therapy.

Recombinant adeno-associated virus-mediated gene transfer for the potential therapy of adenosine deaminase-deficient severe combined immune deficiency.

T. Conlon, T. Flotte, P. Cruz, 2011, Human gene therapy.

A simple method to increase the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo.

B. Byrne, G. Jayandharan, Baozheng Li, 2011, Human gene therapy.

Enhanced long-term transduction and multilineage engraftment of human hematopoietic stem cells transduced with tyrosine-modified recombinant adeno-associated virus serotype 2.

L. Zhong, A. Srivastava, S. Chatterjee, 2010, Human gene therapy.

Self-complementary recombinant adeno-associated viral vectors: packaging capacity and the role of rep proteins in vector purity.

L. Zhong, Baozheng Li, A. Srivastava, 2007, Human gene therapy.

AAV Infection: Protection from Cancer.

A. Srivastava, B. Carter, A. Srivastava, 2017, Human gene therapy.

A simplified immune suppression scheme leads to persistent micro-dystrophin expression in Duchenne muscular dystrophy dogs.

D. Duan, A. Srivastava, Jin-Hong Shin, 2012, Human gene therapy.

Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo.

Liujiang Song, G. Jayandharan, L. Zhong, 2013, Cytotherapy.

Role of integrin cross-regulation in parvovirus B19 targeting.

A. Srivastava, Linyuan Chen, K. A. Weigel-Kelley, 2006, Human gene therapy.

AAV vectors: Are they safe?

A. Srivastava, A. Srivastava, A. Srivastava, 2020, Human gene therapy.

Recombinant human parvovirus B19 vectors.

A. Srivastava, K. A. Weigel-Kelley, 2002, Pathologie-biologie.

Absence of reverse transcriptase activity in human diploid fibroblasts

S. Goldstein, A. Srivastava, R. S. Reis, 1990, Mechanisms of Ageing and Development.

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8+ T cells.

M. Wallet, G. Rogers, R. Herzog, 2017, Blood.

Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.

H. Ertl, R. Herzog, A. Srivastava, 2013, Blood.

Macromolecular Correlates of Cellular Senescence and Cancer

S. Goldstein, A. Srivastava, R. S. Reis, 1985 .

Nucleotide Sequence andOrganization oftheAdeno- Associated Virus 2Genome

A. Srivastava, 1983 .

Development of an AAV DNA-based synthetic vector for the potential gene therapy of hemophilia in children

A. Srivastava, K. Qing, Jakob Shoti, 2022, Frontiers in Microbiology.

Enhanced Transduction of Human Hematopoietic Stem Cells by AAV6 Vectors: Implications in Gene Therapy and Genome Editing

M. Agbandje-McKenna, A. Srivastava, K. Qing, 2020, Molecular therapy. Nucleic acids.

Enhanced Transgene Expression from Recombinant Single-Stranded D-Sequence-Substituted Adeno-Associated Virus Vectors in Human Cell Lines In Vitro and in Murine Hepatocytes In Vivo

R. Samulski, N. Muzyczka, Xiao Xiao, 2014, Journal of Virology.

recombinant AAV vectors in human cell lines in vitro and in murine hepatocytes in

R. Samulski, N. Muzyczka, Xiao Xiao, 2014 .

Rescue and Autonomous Replication of Adeno-Associated Virus Type 2 Genomes Containing Rep-Binding Site Mutations in the Viral p5 Promoter

A. Srivastava, Xu-Shan Wang, 1998, Journal of Virology.

Adeno-associated virus type 2 DNA replication in vivo: mutation analyses of the D sequence in viral inverted terminal repeats

S. Ponnazhagan, K. Qing, A. Srivastava, 1997, Journal of virology.

A novel terminal resolution-like site in the adeno-associated virus type 2 genome

A. Srivastava, X. S. Wang, X. U. Wang, 1997, Journal of virology.

Rescue and replication of adeno-associated virus type 2 as well as vector DNA sequences from recombinant plasmids containing deletions in the viral inverted terminal repeats: selective encapsidation of viral genomes in progeny virions

S. Ponnazhagan, A. Srivastava, Xu-Shan Wang, 1996, Journal of virology.

Versatile adeno-associated virus 2-based vectors for constructing recombinant virions.

A. Srivastava, P. Nahreini, S. Zhou, 1993, Gene.

Successful Replication ofParvovirus B19intheHuman Megakaryocytic Leukemia CellLineMB-02

A. Srivastava, Shangzhen Zhou, 1993 .

Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle.

D. Duan, Xiao Xiao, G. Jayandharan, 2010, Human gene therapy.

Replication of Adenovirus 2 and Adeno-Associated Virus 2 in Young and Senescent Human Diploid Fibroblasts

A. Srivastava, P. Nahreini, A. Srivastava, 1990 .

Role of Molecular Genetics in Hemophilia: From Diagnosis to Therapy

Arun Srivastava, G. Jayandharan, A. Srivastava, 2012, Seminars in Thrombosis & Hemostasis.

High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.

S. Zolotukhin, G. Jayandharan, L. Zhong, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Role of Essential Metal Ions in AAV Vector-Mediated Transduction

A. Srivastava, K. Qing, Frederick Ashby, 2020, Molecular therapy. Methods & clinical development.

AAV D-sequence-mediated suppression of expression of a human major histocompatibility class II gene: Implications in the development of AAV vectors for modulating humoral immune response.

S. Ponnazhagan, S. Boye, A. Srivastava, 2020, Human gene therapy.

AAV3-miRNA vectors for growth suppression of human hepatocellular carcinoma cells in vitro and human liver tumors in a murine xenograft model in vivo

A. Srivastava, K. Qing, C. Ling, 2020, Gene Therapy.

Adeno-Associated Virus D-Sequence-Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene: Implications in the Development of Adeno-Associated Virus Vectors for Modulating Humoral Immune Response

Arun Srivastava, S. Ponnazhagan, S. Boye, 2020 .

Next Generation of Adeno-Associated Virus Vectors for Gene Therapy for Human Liver Diseases.

A. Srivastava, K. Berns, A. Srivastava, 2019, Gastroenterology clinics of North America.

Capsid Modifications for Targeting and Improving the Efficacy of AAV Vectors

H. Büning, A. Srivastava, A. Srivastava, 2019, Molecular therapy. Methods & clinical development.

Next Generation of AAV Vectors for Gene Therapy of Human Liver Diseases

Arun Srivastava, A. Srivastava, K. Berns, 2019 .

Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid.

C. Rice, Arun Srivastava, H. Ertl, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

Coagulation factor IX gene transfer to non-human primates using engineered AAV3 capsid and hepatic optimized expression cassette

Arun Srivastava, G. Gao, R. Herzog, 2021, Molecular therapy. Methods & clinical development.

Identification of nuclear proteins that specifically interact with adeno-associated virus type 2 inverted terminal repeat hairpin DNA

H. Ashktorab, A. Srivastava, A. Srivastava, 1989, Journal of virology.

Nucleotide sequence and organization of the adeno-associated virus 2 genome

A. Srivastava, K. Berns, E. Lusby, 1983, Journal of virology.

Antiviral activity of copper complexes of isoniazid against RNA tumor viruses

A. Srivastava, 2009 .

Pristimerin enhances recombinant adeno-associated virus vector-mediated transgene expression in human cell lines in vitro and murine hepatocytes in vivo.

Arun K. Srivastava, A. Srivastava, G. Aslanidi, 2014, Journal of integrative medicine.

KRAS2 oncogene overexpression in myelodysplastic syndrome with translocation 5;12.

N. Heerema, A. Antony, G. Tricot, 1988, Cancer genetics and cytogenetics.

Chinese Medicine Protein and Peptide in Gene and Cell Therapy.

A. Srivastava, C. Ling, Zi-fei Yin, 2019, Current protein & peptide science.

Cytotoxic genes from traditional Chinese medicine inhibit tumor growth both in vitro and in vivo.

Arun K. Srivastava, A. Srivastava, G. Aslanidi, 2014, Journal of integrative medicine.

Adeno-associated virus type 2-mediated transfer of ecotropic retrovirus receptor cDNA allows ecotropic retroviral transduction of established and primary human cells

T. Bachelot, K. Qing, A. Srivastava, 1997, Journal of virology.

Changes in genetic organization and expression in aging cells.

S. Goldstein, K. Riabowol, A. Srivastava, 1985, Basic life sciences.

Autocrine regulation of growth: II. Glucocorticoids inhibit transcription of c-sis oncogene-specific RNA transcripts.

A. Srivastava, P. Kohler, L. Cornett, 1984, Biochemical and biophysical research communications.

Observations on the phosphonoformic acid inhibition of RNA dependent DNA polymerases.

A. Srivastava, M. Modak, E. Gillerman, 1980, Biochemical and biophysical research communications.

Transduction of folate receptor cDNA into cervical carcinoma cells using recombinant adeno-associated virions delays cell proliferation in vitro and in vivo.

A. Antony, S. Gullapalli, A. Srivastava, 1995, The Journal of clinical investigation.

High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing

A. Srivastava, M. Yoder, M. Tan, 2016, Scientific Reports.

Suppression of human alpha-globin gene expression mediated by the recombinant adeno-associated virus 2-based antisense vectors

S. Ponnazhagan, A. Srivastava, M. L. Nallari, 1994, The Journal of experimental medicine.

Optimization of recombinant adeno-associated viral vectors for human beta-globin gene transfer and transgene expression.

S. Zolotukhin, L. Zhong, A. Rivers, 2008, Human gene therapy.

in vitro Parvovirus B19-induced perturbation of human megakaryocytopoiesis

R. Hoffman, A. Srivastava, R. Cooper, 2011 .

Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted expression from parvovirus B19p6 promoter in primary human hematopoietic progenitor cells.

S. Ponnazhagan, A. Srivastava, M. Yoder, 1999, Journal of hematotherapy & stem cell research.

Transcriptional transactivation of parvovirus B19 promoters in nonpermissive human cells by adenovirus type 2

S. Ponnazhagan, A. Srivastava, A. Srivastava, 1995, Journal of virology.

Parvovirus B19-induced perturbation of human megakaryocytopoiesis in vitro.

R. Hoffman, K. van Besien, A. Srivastava, 1990, Blood.

Replication of B19 parvovirus in highly enriched hematopoietic progenitor cells from normal human bone marrow

L. Lu, A. Srivastava, A. Srivastava, 1988, Journal of virology.

Stable integration and expression in mouse cells of yeast artificial chromosomes harboring human genes.

D. Schlessinger, M. D'urso, A. Srivastava, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Construction of a recombinant human parvovirus B19: adeno-associated virus 2 (AAV) DNA inverted terminal repeats are functional in an AAV-B19 hybrid virus.

R. Samulski, A. Srivastava, C. Srivastava, 1989, Proceedings of the National Academy of Sciences of the United States of America.

AAV3-miRNA vectors for growth suppression of human hepatocellular carcinoma cells in vitro and human liver tumors in a murine xenograft model in vivo

A. Srivastava, K. Qing, C. Ling, 2020, Gene Therapy.

The hepatocyte-specific HNF4α/miR-122 pathway contributes to iron overload-mediated hepatic inflammation.

Yuxiao Tang, A. Srivastava, Hongwei H Zhang, 2017, Blood.

Hepatocyte-specific HNF4α/miR-122 pathway contributes to the iron-overload mediated hepatic inflammation Short title: Role of HNF4α/miR-122 pathway during iron-overload Authors:

Yuxiao Tang, A. Srivastava, Hongwei H Zhang, 2017 .

FK506-binding protein 52 is essential to uterine reproductive physiology controlled by the progesterone receptor A isoform.

Jianming Xu, Weidong Yong, W. Shou, 2006, Molecular endocrinology.

High-efficiency transduction of fibroblasts and mesenchymal stem cells by tyrosine-mutant AAV2 vectors for their potential use in cellular therapy.

G. Jayandharan, L. Zhong, Mengxin Li, 2010, Human gene therapy.

Improved transduction of primary murine hepatocytes by recombinant adeno-associated virus 2 vectors in vivo

W. Shou, A. Srivastava, L. Zhong, 2004, Gene Therapy.

Heat-shock Treatment-mediated Increase in Transduction by Recombinant Adeno-associated Virus 2 Vectors Is Independent of the Cellular Heat-shock Protein 90*

L. Zhong, A. Srivastava, Linyuan Chen, 2004, Journal of Biological Chemistry.

Transgene Expression Transfer : Role of Cellular FKBP 52 Protein in Adeno-Associated Virus Type 2-Mediated Gene

Arun Srivastava, J. Hansen, A. Srivastava, 2001 .

Augmented nuclease activity during cellular senescence in vitro

Arun Srivastava, A. Srivastava, M. Dayton, 1989, Journal of cellular biochemistry.

Lack of site-specific integration of the recombinant adeno-associated virus 2 genomes in human cells.

S. Ponnazhagan, A. Srivastava, A. Srivastava, 1997, Human gene therapy.

High-efficiency transduction of the mouse retina by tyrosine-mutant AAV serotype vectors.

W. Hauswirth, A. Dinculescu, S. Zolotukhin, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Parvoviral Vectors for Human Hematopoietic Gene Therapy

A. Srivastava, A. Srivastava, 1999 .

Adeno-associated virus type 2-mediated transduction of murine hematopoietic cells with long-term repopulating ability and sustained expression of a human globin gene in vivo

S. Ponnazhagan, A. Srivastava, M. Yoder, 1997, Journal of virology.

Evaluation of recombinant adeno-associated virus as a gene transfer vector for the retina.

S. Ponnazhagan, A. Srivastava, A. Srivastava, 1997, Current eye research.

Reverse transcriptase-associated ribonuclease H does not require zinc for catalysis.

A. Srivastava, M. Modak, A. Srivastava, 1979, The Journal of biological chemistry.

Rescue of adeno-associated virus from recombinant plasmids: Gene correction within the terminal repeats of AAV

R. Samulski, N. Muzyczka, A. Srivastava, 1983, Cell.

Adeno-associated virus 2-mediated high efficiency gene transfer into immature and mature subsets of hematopoietic progenitor cells in human umbilical cord blood

S. Heimfeld, H. Broxmeyer, A. Srivastava, 1994, The Journal of experimental medicine.

The genetics of adeno-associated virus.

R. Samulski, N. Muzyczka, P. Hermonat, 1984, Advances in Experimental Medicine and Biology.

A variant t(X;15)(p11;q22) translocation in acute promyelocytic leukemia.

A. Antony, R. Hoffman, H. Boswell, 1987, Cancer genetics and cytogenetics.

Adeno-associated Virus 2-Mediated Transduction and Erythroid Lineage-Restricted Long-Term Expression of the Human β-Globin Gene in Hematopoietic Cells from Homozygous β-Thalassemic Mice

A. Srivastava, K. Qing, M. Yoder, 2001 .

Cellular fusion for gene delivery to SCA1 affected Purkinje neurons

T. Flotte, D. Steindler, D. Borchelt, 2011, Molecular and Cellular Neuroscience.

Parvovirus B19 replication in human umbilical cord blood cells.

N. Munshi, A. Srivastava, A. Srivastava, 1992, Virology.

In vivo tissue-tropism of adeno-associated viral vectors.

Arun Srivastava, A. Srivastava, A. Srivastava, 2016, Current opinion in virology.

Strategies for improving the transduction efficiency of single-stranded adeno-associated virus vectors in vitro and in vivo

G. Jayandharan, L. Zhong, Baozheng Li, 2008, Gene Therapy.

Stable integration of recombinant adeno-associated virus vector genomes after transduction of murine hematopoietic stem cells.

L. Zhong, A. Srivastava, M. Yoder, 2008, Human gene therapy.

Development of Optimized AAV Serotype Vectors for High-Efficiency Transduction at Further Reduced Doses.

Baozheng Li, A. Srivastava, C. Ling, 2016, Human gene therapy methods.

Adeno-Associated Virus: The Naturally Occurring Virus Versus the Recombinant Vector.

A. Srivastava, A. Srivastava, A. Srivastava, 2016, Human gene therapy.

Site-Directed Mutagenesis of Surface-Exposed Lysine Residues Leads to Improved Transduction by AAV2, But Not AAV8, Vectors in Murine Hepatocytes In Vivo.

M. Agbandje-McKenna, Baozheng Li, A. Srivastava, 2015, Human gene therapy methods.

Prevalence of neutralizing antibodies against liver-tropic adeno-associated virus serotype vectors in 100 healthy Chinese and its potential relation to body constitutions.

C. Ling, Arun Srivastava, A. Srivastava, 2015, Journal of integrative medicine.

Lignin nanotubes as vehicles for gene delivery into human cells.

Y. Wang, W. Vermerris, A. Srivastava, 2014, Biomacromolecules.

High-Efficiency Transduction of Primary Human Hematopoietic Stem Cells and Erythroid Lineage-Restricted Expression by Optimized AAV6 Serotype Vectors In Vitro and in a Murine Xenograft Model In Vivo

G. Gao, Liujiang Song, G. Jayandharan, 2013, PloS one.

GENE THERAPY Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-speci fi c CD 8 1 T cells

H. Ertl, R. Herzog, A. Srivastava, 2013 .

Innate Immune Responses to AAV Vectors

G. Rogers, G. Jayandharan, R. Herzog, 2011, Front. Microbio..

Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses

N. Muzyczka, L. Govindasamy, M. Agbandje-McKenna, 2008, Proceedings of the National Academy of Sciences.

Adeno‐associated Viral Vectors in Gene Therapy

L. Zhong, A. Srivastava, Li Zhong, 2007 .

Successful replication of parvovirus B19 in the human megakaryocytic leukemia cell line MB-02

N. Munshi, A. Srivastava, A. Srivastava, 1993, Journal of virology.

Alpha5beta1 integrin as a cellular coreceptor for human parvovirus B19: requirement of functional activation of beta1 integrin for viral entry.

A. Srivastava, K. A. Weigel-Kelley, M. Yoder, 2003, Blood.

Recombinant Human Parvovirus B19 Vectors: Erythrocyte P Antigen Is Necessary but Not Sufficient for Successful Transduction of Human Hematopoietic Cells

Arun Srivastava, A. Srivastava, K. A. Weigel-Kelley, 2001, Journal of Virology.

Rescue and replication signals of the adeno-associated virus 2 genome.

S. Ponnazhagan, A. Srivastava, X. S. Wang, 1995, Journal of molecular biology.

Replication of the adeno-associated virus DNA termini in vitro.

A. Srivastava, 1987, Intervirology.

Human alphoid family of tandemly repeated DNA. Sequence of cloned tetrameric fragments and analysis of familial divergence.

S. Goldstein, A. Srivastava, D. Beranek, 1985, Journal of molecular biology.

AAV3-mediated transfer and expression of the pyruvate dehydrogenase E1 alpha subunit gene causes metabolic remodeling and apoptosis of human liver cancer cells.

P. Stacpoole, A. Srivastava, I. Zolotukhin, 2009, Molecular genetics and metabolism.

Efficient lysis of epithelial ovarian cancer cells by MAGE-A3-induced cytotoxic T lymphocytes using rAAV-6 capsid mutant vector.

B. Kolli, R. Batchu, Oksana V. Gruzdyn, 2014, Vaccine.

Site-specific modifications to AAV8 capsid yields enhanced brain transduction in the neonatal MPS IIIB mouse

S. Boye, R. Mandel, C. Heldermon, 2020, Gene Therapy.

Impaired Intracellular Trafficking of Adeno-Associated Virus Type 2 Vectors Limits Efficient Transduction of Murine Fibroblasts

Arun Srivastava, J. Hansen, A. Srivastava, 2000, Journal of Virology.

Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2

Keyun Qing, Arun Srivastava, J. Hansen, 1999, Nature Medicine.

Adeno-Associated Virus Type 2-Mediated Gene Transfer: Correlation of Tyrosine Phosphorylation of the Cellular Single-Stranded D Sequence-Binding Protein with Transgene Expression in Human Cells In Vitro and Murine Tissues In Vivo

S. Ponnazhagan, D. Kube, V. Dwarki, 1998, Journal of Virology.

Age‐stratified adeno‐associated virus serotype 3 neutralizing and total antibody prevalence in hemophilia A patients from India

K. Lakshmi, M. Agbandje-McKenna, A. Srivastava, 2022, Journal of medical virology.

Gene transfer with adeno-associated virus 2 vectors: the growth factor receptor connection

J. Hansen, A. Srivastava, K. Qing, 1999 .

Adeno-Associated Virus Type 2-Mediated Gene Transfer: Role of Epidermal Growth Factor Receptor Protein Tyrosine Kinase in Transgene Expression

Arun Srivastava, S. Ponnazhagan, D. Kube, 1998, Journal of Virology.

Adeno-associated virus 2-mediated gene transfer in vivo: organ-tropism and expression of transduced sequences in mice.

J. Kaplan, S. Ponnazhagan, A. Srivastava, 1997, Gene.

Prevalence of Adeno-Associated Virus 3 Capsid Binding and Neutralizing Antibodies in Healthy and Hemophilia B Individuals from India

K. Lakshmi, M. Agbandje-McKenna, A. Srivastava, 2022, Human Gene Therapy.

c-Ha-ras-1 proto-oncogene amplification and overexpression during the limited replicative life span of normal human fibroblasts.

S. Goldstein, R. S. Shmookler Reis, A. Srivastava, 1985, The Journal of biological chemistry.

Encapsidation of adeno-associated virus type 2 Rep proteins in wild-type and recombinant progeny virions: Rep-mediated growth inhibition of primary human cells

S. Ponnazhagan, D. Kube, A. Srivastava, 1997, Journal of virology.

Recombinant Human Parvovirus B19 Vectors: Erythroid Cell-Specific Delivery and Expression of Transduced Genes

S. Ponnazhagan, A. Srivastava, M. Yoder, 1998, Journal of Virology.

Differential expression in human cells from the p6 promoter of human parvovirus B19 following plasmid transfection and recombinant adeno-associated virus 2 (AAV) infection: human megakaryocytic leukaemia cells are non-permissive for AAV infection.

N. Munshi, S. Ponnazhagan, A. Srivastava, 1996, The Journal of general virology.

Reverse transcriptase-associated RNase H. Part IV. Pyrophosphate does not inhibit RNase H activity of AMV DNA polymerase.

A. Srivastava, M. Modak, A. Srivastava, 1979, Biochemical and biophysical research communications.

Infection of purified nuclei by adeno-associated virus 2.

J. Hansen, K. Qing, A. Srivastava, 2001, Molecular therapy : the journal of the American Society of Gene Therapy.

Adeno-associated virus 2 co-receptors?-first reply

Keyun Qing, Arun Srivastava, J. Hansen, 1999, Nature Medicine.

Down-regulation of expression of rat pyruvate dehydrogenase E1alpha gene by self-complementary adeno-associated virus-mediated small interfering RNA delivery.

P. Stacpoole, A. Srivastava, A. Lewin, 2007, Mitochondrion.

An animal model of PDH deficiency using AAV8-siRNA vector-mediated knockdown of pyruvate dehydrogenase E1α.

N. Muzyczka, P. Stacpoole, S. Zolotukhin, 2010, Molecular genetics and metabolism.

Novel properties of tyrosine-mutant AAV2 vectors in the mouse retina.

W. Hauswirth, A. Dinculescu, L. Govindasamy, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Limitations of encapsidation of recombinant self-complementary adeno-associated viral genomes in different serotype capsids and their quantitation.

Arun Srivastava, Liujiang Song, A. Srivastava, 2012, Human gene therapy methods.

Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression.

N. Muzyczka, L. Govindasamy, M. Agbandje-McKenna, 2008, Virology.

Cord Blood Transplantation and the Potential for Gene Therapy

Arun Srivastava, H. Broxmeyer, Li Lu, 1995, Annals of the New York Academy of Sciences.

Rationale and strategies for the development of safe and effective optimized AAV vectors for human gene therapy

A. Srivastava, A. Srivastava, A. Srivastava, 2023, Molecular therapy. Nucleic acids.

Authors' Response to Jesse D. Riordan, Hum Gene Ther 2017;28:375-376; DOI: 10.1089/hum.2017.045.

A. Srivastava, B. Carter, A. Srivastava, 2017, Human gene therapy.

Molecular mechanism for the specific inhibition of reverse transcriptase of Rous sarcoma virus by the copper complexes of isonicontinic acid hydrazide.

A. Srivastava, T. Ramakrishnan, A. Antony, 1978, Biochemical pharmacology.

Advances and challenges in the use of recombinant AAV vectors for human gene therapy

A. Srivastava, 2016 .

Role of tyrosine phosphorylation of a cellular protein in adeno-associated virus 2-mediated transgene expression.

S. Ponnazhagan, D. Kube, K. Qing, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of Wild-Type Adeno-Associated Virus Type 2-Like Particles Generated during Recombinant Viral Vector Production and Strategies for Their Elimination

Arun Srivastava, S. Ponnazhagan, D. Kube, 1998, Journal of Virology.

The Adeno-Associated Virus Genome Packaging Puzzle.

Y. Wang, R. Samulski, N. Muzyczka, 2015, Journal of molecular and genetic medicine : an international journal of biomedical research.

Single-polarity recombinant adeno-associated virus 2 vector-mediated transgene expression in vitro and in vivo: mechanism of transduction.

R. Samulski, Xiao Xiao, L. Zhong, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Rescue of the adeno-associated virus 2 genome correlates with alterations in DNA-modifying enzymes in human cells.

A. Srivastava, P. Nahreini, 1992, Intervirology.

Rescue and replication of the adeno-associated virus 2 genome in mortal and immortal human cells.

A. Srivastava, P. Nahreini, 1989, Intervirology.

Adeno-associated virus 2-mediated gene transfer in murine hematopoietic progenitor cells.

H. Broxmeyer, A. Srivastava, A. Srivastava, 1993, Experimental hematology.

Optimizing the transduction efficiency of human hematopoietic stem cells using capsid-modified AAV6 vectors in vitro and in a xenograft mouse model in vivo

Arun Srivastava, Liujiang Song, G. Jayandharan, 2013 .

Obstacles to human hematopoietic stem cell transduction by recombinant adeno‐associated virus 2 vectors

Arun Srivastava, A. Srivastava, A. Srivastava, 2002, Journal of cellular biochemistry. Supplement.

Adeno-associated virus type 2-mediated transduction in primary human bone marrow-derived CD34+ hematopoietic progenitor cells: donor variation and correlation of transgene expression with cellular differentiation

S. Ponnazhagan, D. Kube, K. Qing, 1997, Journal of virology.

Adeno-associated virus 2-mediated transduction and erythroid cell-specific expression of a human beta-globin gene.

G. Stamatoyannopoulos, Q. Li, A. Srivastava, 1996, Gene therapy.

Adeno-Associated Virus Type 2-Mediated Gene Transfer: Altered Endocytic Processing Enhances Transduction Efficiency in Murine Fibroblasts

Arun Srivastava, J. Hansen, A. Srivastava, 2001, Journal of Virology.

Productive life cycle of adeno-associated virus serotype 2 in the complete absence of a conventional polyadenylation signal.

A. Srivastava, G. Aslanidi, C. Ling, 2015, The Journal of general virology.

Adeno-associated virus 2-mediated gene transfer: role of a cellular serine/threonine protein phosphatase in augmenting transduction efficiency

A. Srivastava, L. Zhong, A. Srivastava, 2007, Gene Therapy.

Calpeptin Increases the Activity of Upstream Stimulatory Factor and Induces High Level Globin Gene Expression in Erythroid Cells*

Arun Srivastava, G. Jayandharan, L. Zhong, 2009, The Journal of Biological Chemistry.

Cloning and integration of DNA fragments in human cells via the inverted terminal repeats of the adeno-associated virus 2 genome.

A. Srivastava, P. Nahreini, S. H. Larsen, 1992, Gene.

Human hepatocyte growth factor receptor is a cellular coreceptor for adeno-associated virus serotype 3.

Li Zhong, Binbin Cheng, Baozheng Li, 2010, Human gene therapy.

Adeno-Associated Virus Type 2-Mediated Gene Transfer: Role of Cellular T-Cell Protein Tyrosine Phosphatase in Transgene Expression in Established Cell Lines In Vitro and Transgenic Mice In Vivo

J. Hansen, L. Zhong, A. Srivastava, 2003, Journal of Virology.