J. Sommer

发表

Infectious titer assay for adeno-associated virus vectors with sensitivity sufficient to detect single infectious events.

J. F. Wright, Zhu Zen, Y. Espinoza, 2004, Human gene therapy.

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

J. Rasko, M. Kay, J. Zehnder, 2006, Nature Medicine.

Separation of adeno-associated virus type 2 empty particles from genome containing vectors by anion-exchange column chromatography.

J. F. Wright, J. F. Wright, J. Sommer, 2007, Journal of virological methods.

Identification of factors that contribute to recombinant AAV2 particle aggregation and methods to prevent its occurrence during vector purification and formulation.

J. F. Wright, J. Sommer, G. Pierce, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

Evidence of multiyear factor IX expression by AAV-mediated gene transfer to skeletal muscle in an individual with severe hemophilia B.

M. Ozelo, J. Sommer, K. High, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Undetectable transcription of cap in a clinical AAV vector: implications for preformed capsid in immune responses.

J. F. Wright, J. Sommer, B. Hauck, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Safety and prolonged activity of recombinant factor VIII Fc fusion protein in hemophilia A patients.

J. Dumont, D. Quon, J. Sommer, 2012, Blood.

AAV2-mediated gene delivery to monkey putamen: Evaluation of an infusion device and delivery parameters

Brian M. Suzuki, Kirk W. Johnson, J. Sommer, 2005, Experimental Neurology.

Erratum: CORRIGENDUM: Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

M. Kay, M. Ozelo, J. F. Wright, 2006 .

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

Terrence M. Dobrowsky, Amy M. Holthaus, J. Sommer, 2020 .

A Single Chain Variant of Factor VIII Fc Fusion Protein Retains Normal In Vivo Efficacy but Exhibits Altered In Vitro Activity

G. Toby, J. Sommer, G. Pierce, 2014, PloS one.

Recombinant adeno-associated virus: formulation challenges and strategies for a gene therapy vector.

Chunling Tang, J. F. Wright, J. Sommer, 2003, Current opinion in drug discovery & development.

Comparative field study evaluating the activity of recombinant factor VIII Fc fusion protein in plasma samples at clinical haemostasis laboratories

B. Konkle, J. Sommer, G. Pierce, 2013, Haemophilia : the official journal of the World Federation of Hemophilia.

Recombinant Factor IX Fc Fusion Protein Maintains Full Procoagulant Properties and Exhibits Prolonged Efficacy in Hemophilia B Mice

A. Bitonti, G. Toby, J. Sommer, 2016, PloS one.

Comparative field study: impact of laboratory assay variability on the assessment of recombinant factor IX Fc fusion protein (rFIXFc) activity

J. Sommer, G. Pierce, Haiyan Jiang, 2014, Thrombosis and Haemostasis.

Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B.

J. Dumont, D. Perry, L. Valentino, 2013, The New England journal of medicine.

Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia A.

J. Dumont, I. Nestorov, D. Perry, 2014, Blood.

Evaluation of recombinant factor VIII Fc (Eloctate) activity by thromboelastometry in a multicenter phase 3 clinical trial and correlation with bleeding phenotype

F. Driessler, J. Sommer, G. Pierce, 2017, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Enhanced efficacy of recombinant FVIII in noncovalent complex with PEGylated liposome in hemophilia A mice.

Ji-Yun Kim, J. Sommer, Junliang Pan, 2007, Blood.

hemophilia A Phase 3 study of recombinant factor VIII Fc fusion protein in severe

J. Dumont, I. Nestorov, D. Perry, 2014 .

Inadvertent germline transmission of AAV2 vector: findings in a rabbit model correlate with those in a human clinical trial.

J. Sommer, L. Couto, V. Arruda, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

CD8+ T-cell responses to adeno-associated virus capsid in humans

Marcela V Maus, Hildegund C J Ertl, Haiyan Jiang, 2007, Nature Medicine.

Real‐world assay variability between laboratories in monitoring of recombinant factor IX Fc fusion protein activity in plasma samples

J. Sommer, A. Willemze, A. Sadeghi-Khomami, 2020, International journal of laboratory hematology.

Recombinant FIX Fc fusion protein activity assessment with the one‐stage clotting assay: A multicenter, assessor‐blinded, prospective study in Japan (J‐Field Study)

J. Sommer, K. Fukutake, Tomomi Kobayashi, 2019, International journal of laboratory hematology.

1002. Immune Responses to AAV and to Factor IX in a Phase I Study of AAV-Mediated, Liver-Directed Gene Transfer for Hemophilia B

J. Rasko, M. Kay, M. Ozelo, 2004 .

Developing BIVV001, a new class of factor VIII replacement for hemophilia A that is von Willebrand factor-independent.

Terrence M. Dobrowsky, Amy M. Holthaus, J. Sommer, 2020, Blood.

Effects of transient immunosuppression on adenoassociated, virus-mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy.

J. Sommer, K. High, L. Couto, 2006, Blood.

Human immunoglobulin inhibits liver transduction by AAV vectors at low AAV2 neutralizing titers in SCID mice.

J. Sommer, L. Couto, C. Scallan, 2006, Blood.

Effects of transient immunosuppression on adeno associated virus- mediated, liver-directed gene transfer in rhesus macaques and implications for human gene therapy Running Title: Immunosuppression in AAV8-hFIX treated macaques

J. Sommer, K. High, L. Couto, 2006 .

Erratum: CORRIGENDUM: Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

M. Kay, M. Ozelo, J. F. Wright, 2006 .

Quantification of adeno-associated virus particles and empty capsids by optical density measurement.

Alan McClelland, J. F. Wright, J. Sommer, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Corrigendum to "Inadvertent Germline Transmission of AAV2 Vector: Findings in a Rabbit Model Correlate with Those in a Human Clinical Trial".

J. Sommer, L. Couto, V. Arruda, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.