A. Evagelidis

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Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity

N. Seidah, B. Coutard, Ursula Andréo, 2022, Journal of virology.

Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2’ by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2

N. Seidah, B. Coutard, Ursula Andréo, 2020, bioRxiv.

Implications of Spike-glycoprotein processing at S1/S2 by Furin, at S2’ by Furin and/or TMPRSS2 and shedding of ACE2: cell-to-cell fusion, cell entry and infectivity of SARS-CoV-2

N. Seidah, B. Coutard, Ursula Andréo, 2020, bioRxiv.

Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels

A. Prat, H. Nozach, V. Dive, 2022, bioRxiv.

Phosphorylation of CFTR by PKA promotes binding of the regulatory domain

A. Evagelidis, J. Liao, J. Hanrahan, 2005, The EMBO journal.

Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor).

N. Seidah, B. Coulombe, M. Gauthier, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL‐8 secretion by cystic fibrosis airways

B. Rappaz, David Y. Thomas, A. Evagelidis, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of protein phosphatases in the activation of CFTR (ABCC7) by genistein and bromotetramisole.

A. Evagelidis, J. Hanrahan, J. Luo, 2000, American journal of physiology. Cell physiology.

Basolateral chloride loading by the anion exchanger type 2: role in fluid secretion by the human airway epithelial cell line Calu‐3

S. Alper, A. Evagelidis, J. Liao, 2012, The Journal of physiology.

Regulation of the CFTR channel by phosphorylation

A. Evagelidis, J. Hanrahan, D. Dahan, 2001, Pflügers Archiv.

Asymmetric structure of the cystic fibrosis transmembrane conductance regulator chloride channel pore suggested by mutagenesis of the twelfth transmembrane region.

P. Linsdell, A. Evagelidis, J. Hanrahan, 2001, Biochemistry.

Molecular determinants of anion selectivity in the cystic fibrosis transmembrane conductance regulator chloride channel pore.

P. Linsdell, A. Evagelidis, J. Hanrahan, 2000, Biophysical journal.

Association of Cystic Fibrosis Transmembrane Conductance Regulator and Protein Phosphatase 2C*

A. Evagelidis, J. Hanrahan, D. Dahan, 1999, The Journal of Biological Chemistry.

The motif EXEXXXL in the cytosolic tail of the secretory human proprotein convertase PC7 regulates its trafficking and cleavage activity

N. Seidah, A. Evagelidis, R. Day, 2020, The Journal of Biological Chemistry.

Erratum for Essalmani et al., “Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity”

N. Seidah, B. Coutard, Ursula Andréo, 2022, Journal of Virology.

SKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2

Ursula Andréo, R. Essalmani, Delia Susan-Resiga, 2023, Viruses.

Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin

N. Seidah, R. Essalmani, Delia Susan-Resiga, 2021, The Journal of biological chemistry.

Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR that is shed by Furin

N. Seidah, R. Essalmani, Delia Susan-Resiga, 2021, bioRxiv.

Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator

L. D. Howell, J. Riordan, A. Evagelidis, 2003, Proceedings of the National Academy of Sciences of the United States of America.

PKC phosphorylation modulates PKA-dependent binding of the R domain to other domains of CFTR.

A. Evagelidis, J. Hanrahan, V. Chappe, 2008, American journal of physiology. Cell physiology.

Furin cleaves SARS-CoV-2 spike-glycoprotein at S1/S2 and S2'for viral fusion/entry: indirect role for TMPRSS2

N. Seidah, B. Coutard, Ursula Andréo, 2020 .

CFTR regulation by phosphorylation.

A. Evagelidis, J. Hanrahan, D. Dahan, 2002, Methods in molecular medicine.

Basolateral chloride loading by the anion exchanger type 2: role in fluid secretion by the human airway epithelial cell line Calu‐3

S. Alper, A. Evagelidis, J. Liao, 2012, The Journal of physiology.

PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease.

A. Prat, J. Hamelin, R. Essalmani, 2023, Metabolism: clinical and experimental.

Insights into PCSK9-LDLR Regulation and Trafficking via the Differential Functions of MHC-I Proteins HFE and HLA-C

R. Essalmani, A. Evagelidis, N. Seidah, 2024, Cells.