P. Brest

发表

Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype?

Daniel J Klionsky, Paul Hofman, D. Klionsky, 2020, Autophagy.

Characterizing isomiR variants within the microRNA‐34/449 family

P. Barbry, Benoît Chevalier, K. Lebrigand, 2017, FEBS letters.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC)

P. Brest, P. Hofman, B. Mograbi, 2014, Autophagy.

Autophagy-Driven Cancer Drug Development

E. Gilson, D. Lagadic-Gossmann, Amine Belaid, 2018 .

Autophagopathies: from autophagy gene polymorphisms to precision medicine for human diseases

D. Klionsky, C. Marquette, R. Hung, 2022, Autophagy.

Differential expression and regulation of ADAM17 and TIMP3 in acute inflamed intestinal epithelia.

J. Hugot, X. Hébuterne, E. Selva, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Afa/Dr Diffusely Adhering Escherichia coli Infection in T84 Cell Monolayers Induces Increased Neutrophil Transepithelial Migration, Which in Turn Promotes Cytokine-Dependent Upregulation of Decay-Accelerating Factor (CD55), the Receptor for Afa/Dr Adhesins

P. Brest, P. Hofman, A. Servin, 2003, Infection and Immunity.

The Afa/Dr Adhesins of Diffusely Adhering Escherichia coli Stimulate Interleukin-8 Secretion, Activate Mitogen-Activated Protein Kinases, and Promote Polymorphonuclear Transepithelial Migration in T84 Polarized Epithelial Cells

P. Brest, P. Hofman, A. Servin, 2003, Infection and Immunity.

A multifactorial score including autophagy for prognosis and care of COVID-19 patients

D. Klionsky, M. Landi, P. Brest, 2020, Autophagy.

Autophagy and SQSTM1 on the RHOA(d) again

D. Klionsky, Amine Belaid, P. Brest, 2013, Autophagy.

HAMLET (human α‐lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death

H. Simon, C. Svanborg, P. Brest, 2009, International journal of cancer.

Evaluation of Sample Pooling for SARS-CoV-2 Detection in Nasopharyngeal Swab and Saliva Samples with the Idylla SARS-CoV-2 Test

C. Marquette, S. Leroy, P. Brest, 2021, Microbiology spectrum.

Possible consequences of the COVID-19 pandemic on the use of biospecimens from cancer biobanks for research in academia and bioindustry

D. Simeon-Dubach, P. Brest, P. Hofman, 2020, Nature Medicine.

Autophagy-Modulating Drugs in the SARS-CoV-2 War Open Questions for Harnessing

D. Klionsky, P. Brest, J. Benzaquen, 2020 .

MicroRNA-375/SEC23A as biomarkers of the in vitro efficacy of vandetanib

N. Guevara, A. Bozec, J. Santini, 2016, Oncotarget.

Thyroid tumours of uncertain malignant potential: frequency and diagnostic reproducibility

N. Guevara, J. Santini, B. Franc, 2009, Virchows Archiv.

Can the microRNA signature distinguish between thyroid tumors of uncertain malignant potential and other well-differentiated tumors of the thyroid gland?

N. Guevara, J. Santini, P. Barbry, 2011, Endocrine-related cancer.

Processing body dynamics drive non-genetic MEK inhibitors tolerance by fine-tuning KRAS and NRAS translation

B. Mari, R. Rezzonico, P. Brest, 2021, bioRxiv.

The Carcinogen Cadmium Activates Lysine 63 (K63)-Linked Ubiquitin-Dependent Signaling and Inhibits Selective Autophagy

V. Imbert, J. Peyron, Amine Belaid, 2021, Cancers.

Setting-Up a Rapid SARS-CoV-2 Genome Assessment by Next-Generation Sequencing in an Academic Hospital Center (LPCE, Louis Pasteur Hospital, Nice, France)

C. Marquette, S. Leroy, R. Schiappa, 2022, Frontiers in Medicine.

Histone deacetylase inhibitors promote the tumoricidal effect of HAMLET.

A. Hamiche, C. Svanborg, P. Brest, 2007, Cancer research.

HAMLET promotes the tumoricidal effect of HDAC inhibitors

C. Svanborg, P. Brest, A. Mossberg, 2007 .

FAST TRACK HAMLET (human a-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death

H. Simon, C. Svanborg, P. Brest, 2009 .

Using Genetics To Dissect SARS-CoV-2 Infection

G. Milano, P. Brest, P. Hofman, 2020, Trends in Genetics.

Human Polymorphonuclear Leukocytes are Sensitive In Vitro to Helicobacter pylori VacA Toxin

P. Auberger, E. Selva, P. Brest, 2006, Helicobacter.

Effect of Helicobacter pylori on Polymorphonuclear Leukocyte Migration across Polarized T84 Epithelial Cell Monolayers: Role of Vacuolating Toxin VacA and cagPathogenicity Island

P. Auberger, A. Galmiche, P. Boquet, 2000, Infection and Immunity.

Effect of Helicobacter pylori on Polymorphonuclear Leukocyte Migration across Polarized T84 Epithelial Cell Monolayers: Role of Vacuolating Toxin VacA and cag Pathogenicity Island

P. Auberger, A. Galmiche, P. Boquet, 2000 .

Pathogenesis of Helicobacter pylori Infection

S. Bereswill, P. Brest, P. Hofman, 2004, Helicobacter.

Helicobacter pylori Lipopolysaccharide Hinders Polymorphonuclear Leucocyte Apoptosis

P. Auberger, F. Luciano, P. Boquet, 2001, Laboratory Investigation.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Hyperprogression under Immune Checkpoint Inhibitor: a potential role for germinal immunogenetics

G. Milano, P. Brest, F. Peyrade, 2020, Scientific Reports.

Increased Rate of Apoptosis and Diminished Phagocytic Ability of Human Neutrophils Infected with Afa/Dr Diffusely Adhering Escherichia coli Strains

P. Auberger, M. Herrant, E. Selva, 2004, Infection and Immunity.

Escherichia coli cytotoxic necrotizing factor‐1 (CNF‐1) increases the adherence to epithelia and the oxidative burst of human polymorphonuclear leukocytes but decreases bacteria phagocytosis

G. Le Negrate, P. Boquet, P. Brest, 2000, Journal of leukocyte biology.

Rho GTPase Is Activated by Cytotoxic Necrotizing Factor 1 in Peripheral Blood T Lymphocytes: Potential Cytotoxicity for Intestinal Epithelial Cells

P. Auberger, A. Loubat, P. Brest, 2003, Infection and Immunity.

Identification of a circulating immunological signature predictive of response to immune checkpoint inhibitors in patients with advanced non‐small cell lung cancer

C. Marquette, P. Brest, J. Benzaquen, 2022, Clinical and translational medicine.

Etiology of Crohn’s disease: many roads lead to autophagy

P. Brest, P. Hofman, A. Darfeuille‐Michaud, 2012, Journal of Molecular Medicine.

High expression of TRF2, SOX10, and CD10 in circulating tumor microemboli detected in metastatic melanoma patients. A potential impact for the assessment of disease aggressiveness

E. Gilson, P. Bahadoran, R. Ballotti, 2016, Cancer medicine.

Autophagy : Moving Benchside Promises to Patient Bedsides.

Y. Graba, Amine Belaid, P. Brest, 2015, Current cancer drug targets.

COVID-19 vaccination and cancer immunotherapy: should they stick together?

G. Milano, P. Brest, P. Hofman, 2021, British journal of cancer.

Impact of Kras mutant subtypes on PD-L1 expression in lung adenocarcinoma

C. Marquette, P. Brest, P. Hofman, 2016 .

Comparison of unsupervised machine-learning methods to identify metabolomic signatures in patients with localized breast cancer

G. Milano, P. Brest, B. Mograbi, 2020, Computational and structural biotechnology journal.

Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors

G. Milano, P. Brest, F. Peyrade, 2019, Investigational New Drugs.

Germinal immunogenetics as a predictive factor for immunotherapy.

G. Milano, P. Brest, J. Gal, 2019, Critical reviews in oncology/hematology.

Daily Practice Assessment of KRAS Status in NSCLC Patients: A New Challenge for the Thoracic Pathologist Is Right around the Corner

P. Brest, P. Hofman, B. Mograbi, 2022, Cancers.

Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration.

X. Hébuterne, R. Unwin, P. Brest, 2010, American journal of physiology. Gastrointestinal and liver physiology.

An Atlas of the Genetic Variations Linking Dysregulation of Autophagy to Human Diseases: The Missing Environmental Link

E. Gilson, D. Klionsky, C. Marquette, 2020 .

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

Annick Harel-Bellan, Pascal Barbry, Bernard Mari, 2011, Nature Genetics.

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

D. Klionsky, Amine Belaid, P. Brest, 2013, Cancer research.

GC content shapes mRNA storage and decay in human cells

D. Weil, N. Standart, Yves Clément, 2019, eLife.

GC content shapes mRNA decay and storage in human cells

H. R. Crollius, D. Weil, N. Standart, 2018, bioRxiv.

Apoptosis and tumor cell death in response to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

C. Svanborg, P. Brest, O. Hallgren, 2008, Advances in experimental medicine and biology.

Profiling the Non-genetic Origins of Cancer Drug Resistance with a Single-Cell Functional Genomics Approach Using Predictive Cell Dynamics.

Luis C. Gomes-Pereira, Pascal Barbry, Paul Hofman, 2020, Cell systems.

Two Panels of Plasma MicroRNAs as Non-Invasive Biomarkers for Prediction of Recurrence in Resectable NSCLC

Paul Hofman, Amine Belaid, C. Marquette, 2013, PloS one.

MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells.

J. Santini, P. Barbry, B. Mari, 2011, Endocrine-related cancer.

Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

B. Mari, C. Staedel, P. Brest, 2018, Nucleic acids research.

Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

B. Mari, C. Staedel, P. Brest, 2016, Nucleic acids research.

Checkpoint inhibitors in a marriage: consented or arranged?

G. Milano, P. Brest, B. Mograbi, 2022, British Journal of Cancer.

cell death in thyroid cancer cells

S. Antipolis, J. Santini, P. Barbry, 2011 .

Assessment of morphology, antigenicity, and nucleic acid integrity for diagnostic thyroid pathology using formalin substitute fixatives.

J. Santini, E. Selva, P. Brest, 2009, Thyroid : official journal of the American Thyroid Association.

Human polymorphism at microRNAs and microRNA target sites.

Charles E. Vejnar, Daniel R. Caffrey, L. Liang, 2013 .

In papillary thyroid carcinoma, TIMP-1 expression correlates with BRAFV600E mutation status and together with hypoxia-related proteins predicts aggressive behavior

N. Guevara, A. Bozec, J. Santini, 2013, Virchows Archiv.

KRAS Mutations in Lung Adenocarcinoma: Molecular and Epidemiological Characteristics, Methods for Detection, and Therapeutic Strategy Perspectives.

A. Didier, C. Marquette, J. Mazières, 2015, Current molecular medicine.

Autophagy and Crohn's disease: at the crossroads of infection, inflammation, immunity, and cancer.

X. Hébuterne, P. Brest, P. Hofman, 2010, Current molecular medicine.

Subversion of Autophagy in Adherent Invasive Escherichia coli-Infected Neutrophils Induces Inflammation and Cell Death

X. Hébuterne, P. Brest, P. Hofman, 2012, PloS one.

Risk predisposition for Crohn disease: A “ménage à trois” combining IRGM allele, miRNA and xenophagy

P. Brest, P. Hofman, B. Mograbi, 2011, Autophagy.

3 Epithelial to Mesenchymal Transition in Microbial Pathogenesis

P. Brest, P. Hofman, A. Chargui, 2018 .

PD-L1 regulation revisited: impact on immunotherapeutic strategies.

G. Milano, P. Brest, P. Hofman, 2021, Trends in molecular medicine.

Gene expression profiling in human gastric mucosa infected with Helicobacter pylori

P. Barbry, B. Mari, X. Hébuterne, 2007, Modern Pathology.

Host Polymorphisms May Impact SARS-CoV-2 Infectivity

G. Milano, P. Brest, B. Mograbi, 2020, Trends in Genetics.

Escherichia coli Cytotoxic Necrotizing Factor 1 Inhibits Intestinal Epithelial Wound Healing In Vitro after Mechanical Injury

B. Mari, P. Brest, P. Hofman, 2004, Infection and Immunity.

Inhibition of apoptosis induced by heat shock preconditioning is associated with decreased phagocytosis in human polymorphonuclear leukocytes through inhibition of Rac and Cdc42

P. Auberger, A. Loubat, E. Selva, 2007, Immunology and cell biology.

Response of CAIX and CAXII to in vitro re-oxygenation and clinical significance of the combined expression in NSCLC patients.

J. Pouysségur, N. Mazure, P. Brest, 2013, Lung cancer.

New technologies for improved relevance in miRNA research.

G. Vassaux, B. Mari, R. Rezzonico, 2021, Trends in genetics : TIG.

J. Lemonnier, G. Romieu, J. Pierga, 2020, Pharmaceuticals.

Checkpoint inhibitors in a marriage: consented or arranged?

G. Milano, P. Brest, P. Hofman, 2022, British journal of cancer.

Effect of mutant variants of the KRAS gene on PD-L1 expression and on the immune microenvironment and association with clinical outcome in lung adenocarcinoma patients.

C. Marquette, S. Leroy, J. Mazières, 2018, Lung cancer.

Host genetic variability and determinants of severe COVID-19

G. Milano, P. Brest, B. Mograbi, 2022, Trends in Genetics.

MiR-223-3p inhibits angiogenesis and promotes resistance to cetuximab in head and neck squamous cell carcinoma

A. Bozec, P. Brest, P. Hofman, 2017, Oncotarget.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Hyperprogression under Immune Checkpoint Inhibitor: a potential role for germinal immunogenetics

G. Milano, P. Brest, F. Peyrade, 2020, Scientific Reports.

Cholesterol efflux pathways hinder KRAS-driven lung tumor progenitor cell expansion.

C. Bertolotto, P. Barbry, B. Mari, 2023, Cell stem cell.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

More light on cancer and COVID-19 reciprocal interaction

G. Milano, P. Brest, P. Hofman, 2021, British Journal of Cancer.

KRAS and NRAS Translation Is Increased upon MEK Inhibitors-Induced Processing Bodies Dissolution

B. Mari, R. Rezzonico, P. Brest, 2023, Cancers.

Possible consequences of the COVID-19 pandemic on the use of biospecimens from cancer biobanks for research in academia and bioindustry

P. Brest, P. Hofman, Hicham Lahlou, 2020, Nature Medicine.

Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality.

P. Brest, B. Mograbi, Barnabé Roméo, 2023, Trends in molecular medicine.

Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition

B. Mari, C. Staedel, P. Brest, 2016, Nucleic acids research.

Checkpoint inhibitors and anti-angiogenic agents: a winning combination.

P. Brest, B. Mograbi, Paul Hofman, 2023, British Journal of Cancer.

Autophagy and Crohn's disease: at the crossroads of infection, inflammation, immunity, and cancer.

Amine Belaid, P. Brest, B. Mograbi, 2010, Current molecular medicine.

Etiology of Crohn’s disease: many roads lead to autophagy

P. Brest, P. Hofman, A. Darfeuille‐Michaud, 2012, Journal of Molecular Medicine.

Assessment of morphology, antigenicity, and nucleic acid integrity for diagnostic thyroid pathology using formalin substitute fixatives.

J. Santini, E. Selva, P. Brest, 2009, Thyroid : official journal of the American Thyroid Association.

Should evidence of an autolysosomal de-acidification defect in Alzheimer and Parkinson diseases call for caution in prescribing chronic PPI and DMARD?

D. Klionsky, P. Brest, B. Mograbi, 2023, Autophagy.

Guidelines for the use and interpretation of assays for monitoring autophage

T. P. Neufeld, Thomas J. Begley, H. Coller, 2012 .

2012 Landes Bioscience. Do not distribute. Guidelines for the use and interpretation of assays for monitoring autophagy

Thomas J. Begley, H. Coller, F. Chisari, 2012 .

Germinal Immunogenetics predict treatment outcome for PD-1/PD-L1 checkpoint inhibitors

G. Milano, P. Brest, F. Peyrade, 2019, Investigational new drugs.

Disrupting USP39 deubiquitinase function impairs the survival and migration of multiple myeloma cells through ZEB1 degradation

F. Luciano, P. Brest, M. Dufies, 2024, bioRxiv.

Response of CAIX and CAXII to in vitro re-oxygenation and clinical significance of the combined expression in NSCLC patients.

J. Pouysségur, N. Mazure, P. Brest, 2013, Lung cancer.

Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype?

D. Klionsky, P. Brest, J. Benzaquen, 2020, Autophagy.