Yuxian He

发表

Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

Christian Drosten, Susanne Pfefferle, Elizabeth Soilleux, 2011, Journal of Virology.

Cleavage and Activation of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein by Human Airway Trypsin-Like Protease

Christian Drosten, Olaf Jahn, Elizabeth J. Soilleux, 2011, Journal of Virology.

Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity

K. Yuen, Shibo Jiang, L. Du, 2007, Biochemical and Biophysical Research Communications.

A novel neutralizing antibody against diverse clades of H5N1 influenza virus and its mutants capable of airborne transmission.

Yusen Zhou, Yuxian He, B. Zheng, 2014, Antiviral research.

The Epitope and Neutralization Mechanism of AVFluIgG01, a Broad-Reactive Human Monoclonal Antibody against H5N1 Influenza Virus

Yuxian He, R. Wu, Xingxing Li, 2012, PloS one.

Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2.

Shibo Jiang, L. Du, Wanbo Tai, 2020, Antiviral research.

Long-Term Persistence of Robust Antibody and Cytotoxic T Cell Responses in Recovered Patients Infected with SARS Coronavirus

J. Xie, Zhiwei Chen, Linqi Zhang, 2006, PloS one.

Identification of Immunodominant Epitopes on the Membrane Protein of the Severe Acute Respiratory Syndrome-Associated Coronavirus

Shibo Jiang, Shibo Jiang, J. Niu, 2005, Journal of Clinical Microbiology.

In Vitro Selection and Characterization of HIV-1 Variants with Increased Resistance to Sifuvirtide, a Novel HIV-1 Fusion Inhibitor*

Linqi Zhang, Lu Lu, Shibo Jiang, 2010, The Journal of Biological Chemistry.

Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors

A. Debnath, P. Tien, Gengfu Xiao, 2004, The Lancet.

Identification of a novel HIV-1-neutralizing antibody from a CRF07_BC-infected Chinese donor.

Y. Qiao, Yuxian He, Youxiang Sun, 2017, Oncotarget.

Analysis of the immunogenic properties of a single-chain polypeptide analogue of the HIV-1 gp120-CD4 complex in transgenic mice that produce human immunoglobulins.

Yuxian He, A. Pinter, P. D'Agostino, 2003, Vaccine.

Conserved Residue Lys574 in the Cavity of HIV-1 Gp41 Coiled-coil Domain Is Critical for Six-helix Bundle Stability and Virus Entry*

A. Debnath, F. Kirchhoff, Hong Lu, 2007, Journal of Biological Chemistry.

Cell membrane-anchored anti-HIV single-chain antibodies and bifunctional inhibitors targeting the gp41 fusion protein: new strategies for HIV gene therapy

Yuxian He, Li Li, Yuanmei Zhu, 2021, Emerging microbes & infections.

Therapeutic Efficacy and Resistance Selection of a Lipopeptide Fusion Inhibitor in Simian Immunodeficiency Virus-Infected Rhesus Macaques

C. Qin, Yuxian He, Q. Wei, 2020, Journal of Virology.

Biophysical Property and Broad Anti-HIV Activity of Albuvirtide, a 3-Maleimimidopropionic Acid-Modified Peptide Fusion Inhibitor

Yuxian He, Youchun Wang, Lifeng Cai, 2012, PloS one.

The NS1 protein of influenza a virus interacts with heat shock protein Hsp90 in human alveolar basal epithelial cells: Implication for virus-induced apoptosis

Yuxian He, Zhiliang Cao, Hongbin Song, 2011, Virology Journal.

Highly pathogenic avian influenza A virus H5N1 NS1 protein induces caspase-dependent apoptosis in human alveolar basal epithelial cells

Yuxian He, Hongbin Song, Yutao Yang, 2010, Virology Journal.

Distinct Mechanisms of Neutralization by Monoclonal Antibodies Specific for Sites in the N-Terminal or C-Terminal Domain of Murine Leukemia Virus SU

Yuxian He, A. Pinter, M. Burkhart, 2003, Journal of Virology.

Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells

Shibo Jiang, L. Du, Yusen Zhou, 2009, Biochemical and Biophysical Research Communications.

A 219-mer CHO-expressing receptor-binding domain of SARS-CoV S protein induces potent immune responses and protective immunity.

Shibo Jiang, L. Du, Yusen Zhou, 2010, Viral immunology.

Adaptation of SARS-CoV-2 in BALB/c mice for testing vaccine efficacy

Yan Li, Shibo Jiang, Yusen Zhou, 2020, Science.

Self-Reported Walking Pace and Risk of Cardiovascular Diseases: A Two-Sample Mendelian Randomization Study

Yuxian He, Liangrong Zheng, Lu Chen, 2022, Frontiers in Genetics.

Epitope Mapping of M36, a Human Antibody Domain with Potent and Broad HIV-1 Inhibitory Activity

D. Dimitrov, P. Prabakaran, Jianping Sun, 2013, PloS one.

Induction of protection against divergent H5N1 influenza viruses using a recombinant fusion protein linking influenza M2e to Onchocerca volvulus activation associated protein-1 (ASP-1) adjuvant.

Shibo Jiang, L. Du, Yusen Zhou, 2010, Vaccine.

Intranasal Vaccination of Recombinant Adeno-Associated Virus Encoding Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Spike Protein Induces Strong Mucosal Immune Responses and Provides Long-Term Protection against SARS-CoV Infection1

K. Yuen, Shibo Jiang, L. Du, 2008, The Journal of Immunology.

Pan-coronavirus fusion inhibitors possess potent inhibitory activity against HIV-1, HIV-2, and simian immunodeficiency virus

Yuxian He, Yuanmei Zhu, Hui-hui Chong, 2021, Emerging microbes & infections.

SARS-CoV-2-derived fusion inhibitor lipopeptides exhibit highly potent and broad-spectrum activity against divergent human coronaviruses

Yuxian He, Yuanmei Zhu, Hui-hui Chong, 2021, Signal Transduction and Targeted Therapy.

The Trp64Arg polymorphism in β3 adrenergic receptor (ADRB3) gene is associated with adipokines and plasma lipids: a systematic review, meta-analysis, and meta-regression

Yuxian He, Zhi-yang Luo, W. Cao, 2020, Lipids in Health and Disease.

Spinal Cord Stimulation Attenuates Neural Remodeling, Inflammation, and Fibrosis After Myocardial Infarction.

Yuxian He, Liangrong Zheng, Jie Han, 2021, Neuromodulation : journal of the International Neuromodulation Society.

Identification of Immunodominant Sites on the Spike Protein of Severe Acute Respiratory Syndrome (SARS) Coronavirus: Implication for Developing SARS Diagnostics and Vaccines

Shibo Jiang, Yusen Zhou, Yuxian He, 2004, The Journal of Immunology.

The Tryptophan-Rich Motif of HIV-1 gp41 Can Interact with the N-Terminal Deep Pocket Site: New Insights into the Structure and Function of gp41 and Its Inhibitors

Yuxian He, Xiaohui Ding, Yuanmei Zhu, 2019, Journal of Virology.

Antigenicity and Immunogenicity of SARS-CoV

Shibo Jiang, Yuxian He, 2005 .

Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients

Shibo Jiang, L. Du, Yuxian He, 2010, Virology Journal.

Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection

K. Yuen, Shibo Jiang, L. Du, 2008, Vaccine.

Mucosal Immune Responses and Provides (SARS-CoV) Spike Protein Induces Strong Respiratory Syndrome Coronavirus Receptor-Binding Domain of Severe Acute Adeno-Associated Virus Encoding Intranasal Vaccination of Recombinant

K. Yuen, Shibo Jiang, L. Du, 2007 .

Inactivated SARS-CoV vaccine elicits high titers of spike protein-specific antibodies that block receptor binding and virus entry

Shibo Jiang, Yusen Zhou, Yuxian He, 2004, Biochemical and Biophysical Research Communications.

Immunogenicity of SARS-CoV: the Receptor-Binding Domain of S Protein is a Major Target of Neutralizing Antibodies

Yuxian He, 2006, Advances in experimental medicine and biology.

Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies

D. Dimitrov, R. Baric, K. Subbarao, 2007, Proceedings of the National Academy of Sciences.

Monotherapy with a low-dose lipopeptide HIV fusion inhibitor maintains long-term viral suppression in rhesus macaques

C. Qin, Yuxian He, Q. Wei, 2019, PLoS pathogens.

Conserved Residue Asn-145 in the C-Terminal Heptad Repeat Region of HIV-1 gp41 is Critical for Viral Fusion and Regulates the Antiviral Activity of Fusion Inhibitors

Yuxian He, Yuanmei Zhu, Hui-hui Chong, 2019, Viruses.

A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro, Ex Vivo, and In Vivo Antiviral Activity

C. Qin, Yusen Zhou, Yuxian He, 2017, Journal of Virology.

DNA Triplex-Based Complexes Display Anti-HIV-1-Cell Fusion Activity.

Tao Zhang, Liang Xu, Keliang Liu, 2015, Nucleic acid therapeutics.

DNA Duplexes with Hydrophobic Modifications Inhibit Fusion between HIV-1 and Cell Membranes

Wei Chen, Liang Xu, Keliang Liu, 2013, Antimicrobial Agents and Chemotherapy.

The M-T Hook Structure Is Critical for Design of HIV-1 Fusion Inhibitors*

Jianping Sun, Yuxian He, Zonglin Qiu, 2012, The Journal of Biological Chemistry.

Discovery of Critical Residues for Viral Entry and Inhibition through Structural Insight of HIV-1 Fusion Inhibitor CP621–652*

Yuxian He, Zonglin Qiu, Meitian Wang, 2012, The Journal of Biological Chemistry.

Conserved Salt-bridge between the Nand C-Terminal Heptad Repeat Regions of HIV-1 gp 41 Core Structure Is Critical for Virus Entry and Inhibition

A. Debnath, Shibo Jiang, Shuwen Liu, 2008 .

Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41.

A. Debnath, Hong Lu, Shibo Jiang, 2005, Biochimica et biophysica acta.

The M-T hook structure increases the potency of HIV-1 fusion inhibitor sifuvirtide and overcomes drug resistance.

Y. Qiao, Jianping Sun, Yuxian He, 2014, The Journal of antimicrobial chemotherapy.

Short‐peptide fusion inhibitors with high potency against wild‐type and enfuvirtide‐resistant HIV‐1

Jianping Sun, Yuxian He, Zonglin Qiu, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

RNA helicase DDX5 participates in oxLDL‐induced macrophage scavenger receptor 1 expression by suppressing mRNA degradation

Yuxian He, Xiaotong Hu, Liangrong Zheng, 2018, Experimental cell research.

Design and Evaluation of Sifuvirtide, a Novel HIV-1 Fusion Inhibitor*

Yonghong Xiao, Linqi Zhang, Hong Lu, 2008, Journal of Biological Chemistry.

Generation of HIV-resistant cells with a single-domain antibody: implications for HIV-1 gene therapy

Yue Chen, Yuxian He, Li Li, 2021, Cellular & Molecular Immunology.

Structural and Functional Characterization of the Secondary Mutation N126K Selected by Various HIV-1 Fusion Inhibitors

Yuxian He, Xiaohui Ding, Yang Su, 2020, Viruses.

Structural and Functional Characterization of Membrane Fusion Inhibitors with Extremely Potent Activity against Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus

Yuxian He, Yuanmei Zhu, Hui-hui Chong, 2018, Journal of Virology.

Molecular mechanism of HIV-1 resistance to sifuvirtide, a clinical trial–approved membrane fusion inhibitor

Yuxian He, Xiaohui Ding, Yuanmei Zhu, 2018, The Journal of Biological Chemistry.

Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition

Xinquan Wang, Yuxian He, Xiaohui Ding, 2017, Journal of Virology.

A Helical Short-Peptide Fusion Inhibitor with Highly Potent Activity against Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus

N. Taveira, Yuxian He, Xiaohui Ding, 2016, Journal of Virology.

An effective conjugation strategy for designing short peptide-based HIV-1 fusion inhibitors.

Keliang Liu, Chao Wang, Yuxian He, 2016, Organic & biomolecular chemistry.

Genetic Pathway of HIV-1 Resistance to Novel Fusion Inhibitors Targeting the Gp41 Pocket

Y. Qiao, Yuxian He, Zonglin Qiu, 2015, Journal of Virology.

The N-Terminal T-T Motif of a Third-Generation HIV-1 Fusion Inhibitor Is Not Required for Binding Affinity and Antiviral Activity.

Yuxian He, Zonglin Qiu, Yang Su, 2015, Journal of medicinal chemistry.

Mechanism of HIV-1 Resistance to Short-Peptide Fusion Inhibitors Targeting the Gp41 Pocket

Yuxian He, Zonglin Qiu, Yang Su, 2015, Journal of Virology.

Design of a highly potent HIV-1 fusion inhibitor targeting the gp41 pocket

Yuxian He, Zonglin Qiu, Yang Su, 2015, AIDS.

Two M-T hook residues greatly improve the antiviral activity and resistance profile of the HIV-1 fusion inhibitor SC29EK

Y. Qiao, Jianping Sun, Yuxian He, 2014, Retrovirology.

Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide

Yuxian He, Q. Wei, Z. Cong, 2021, Cell.

Identification and characterization of a subpocket on the N-trimer of HIV-1 Gp41: implication for viral entry and drug target

Yuxian He, Zonglin Qiu, Yang Su, 2015, AIDS.

Potent HIV fusion inhibitors against Enfuvirtide-resistant HIV-1 strains

Shibo Jiang, Zhi Qi, Hong Lu, 2008, Proceedings of the National Academy of Sciences.

Design of a Bispecific HIV Entry Inhibitor Targeting the Cell Receptor CD4 and Viral Fusion Protein Gp41

Yuxian He, Li Li, Yuanmei Zhu, 2022, Frontiers in Cellular and Infection Microbiology.

Lipopolysaccharide mediates time‐dependent macrophage M1/M2 polarization through the Tim‐3/Galectin‐9 signalling pathway

Yuxian He, Xiying Wang, Wang Zhang, 2019, Experimental cell research.

Identification of a Critical Motif for the Human Immunodeficiency Virus Type 1 (HIV-1) gp41 Core Structure: Implications for Designing Novel Anti-HIV Fusion Inhibitors

Hong Lu, Shibo Jiang, Yuxian He, 2008, Journal of Virology.

Is catheter-based foam sclerotherapy more effective than direct foam sclerotherapy when combined with high ligation for the treatment of primary great saphenous vein incompetence?

Yuxian He, Yikuan Chen, Mingyi Zhang, 2022, Vascular.

Exceptionally Potent and Broadly Cross-Reactive, Bispecific Multivalent HIV-1 Inhibitors Based on Single Human CD4 and Antibody Domains

D. Dimitrov, P. Prabakaran, T. Ying, 2013, Journal of Virology.

Preparation of an Environmentally Friendly Nano-Insecticide through Encapsulation in Polymeric Liposomes and Its Insecticidal Activities against the Fall Armyworm, Spodoptera frugiperda

Yuxian He, Li-Li Qiu, Qiquan Liu, 2022, Insects.

Potent inhibition of diverse Omicron sublineages by SARS-CoV-2 fusion-inhibitory lipopeptides

Yuxian He, Yuanmei Zhu, Hui-hui Chong, 2022, Antiviral Research.

In Vitro Selection and Characterization of HIV-1 Variants with Increased Resistance to LP-40, Enfuvirtide-Based Lipopeptide Inhibitor

Yuxian He, Yuanmei Zhu, Hui-hui Chong, 2022, International journal of molecular sciences.

Characterization of Antibodies That Inhibit HIV gp120 Antigen Processing and Presentation

M. Gorny, James E. Robinson, Yuxian He, 2005, Retrovirology.

Resistance profile and mechanism of severe acute respiratory syndrome coronavirus-2 variants to LCB1 inhibitor targeting the spike receptor-binding motif

Yuxian He, Yuanmei Zhu, Hui-hui Chong, 2022, Frontiers in Microbiology.

SARS-CoV-2 fusion-inhibitory lipopeptides maintain high potency against divergent variants of concern including Omicron

L. Ren, Jianwei Wang, X. Lei, 2022, Emerging microbes & infections.

rOv-ASP-1, a recombinant secreted protein of the helminth Onchocercavolvulus, is a potent adjuvant for inducing antibodies to ovalbumin, HIV-1 polypeptide and SARS-CoV peptide antigens

Shibo Jiang, Yuxian He, S. Lustigman, 2005, Vaccine.

Two M-T hook residues greatly improve the antiviral activity and resistance profile of the HIV-1 fusion inhibitor SC29EK

Y. Qiao, Jianping Sun, Yuxian He, 2014, Retrovirology.

Development of highly effective LCB1-based lipopeptides targeting the spike receptor-binding motif of SARS-CoV-2

Yuxian He, Guangyu Zhao, Yuanmei Zhu, 2023, Antiviral Research.

N-Substituted Pyrrole Derivatives as Novel Human Immunodeficiency Virus Type 1 Entry Inhibitors That Interfere with the gp41 Six-Helix Bundle Formation and Block Virus Fusion

A. Debnath, Hong Lu, Shibo Jiang, 2004, Antimicrobial Agents and Chemotherapy.

Safety Assessment of Microbicide 2P23 on the Rectal and Vaginal Microbiota and Its Antiviral Activity on HIV Infection

Yuxian He, Ji Wang, Xiaobo Li, 2021, Frontiers in Immunology.

Cellulose acetate 1,2-benzenedicarboxylate inhibits infection by cell-free and cell-associated primary HIV-1 isolates.

Hong Lu, R. Shattock, Shuwen Liu, 2006, AIDS research and human retroviruses.

IFITM Proteins Restrict Viral Membrane Hemifusion

E. Gratton, Shilei Ding, James C. Lee, 2013, PLoS pathogens.

Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus Spike Protein Contains Multiple Conformation-Dependent Epitopes that Induce Highly Potent Neutralizing Antibodies

Shibo Jiang, Hong Lu, Shibo Jiang, 2005, The Journal of Immunology.

Structure-based design and characterization of novel fusion-inhibitory lipopeptides against SARS-CoV-2 and emerging variants

T. Jiao, L. Ren, Jianwei Wang, 2021, Emerging microbes & infections.

Design of Potent Membrane Fusion Inhibitors against SARS-CoV-2, an Emerging Coronavirus with High Fusogenic Activity

Yuxian He, Yuanmei Zhu, Hui-hui Chong, 2020, Journal of Virology.

Measuring Recent Thymic Emigrants in Blood of Normal and HIV-1–Infected Individuals before and after Effective Therapy

Paul Palumbo, D. Ho, Steven Wolinsky, 1999, The Journal of experimental medicine.

Development of subunit vaccines against severe acute respiratory syndrome.

Shibo Jiang, L. Du, Yuxian He, 2008, Drugs of today.

Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model

Yan Guo, Guangyu Zhao, Shibo Jiang, 2006, Vaccine.

Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine

Shibo Jiang, Wenhui Li, Shibo Jiang, 2004, Biochemical and Biophysical Research Communications.

Screening HLA-A-restricted T cell epitopes of SARS-CoV-2 and the induction of CD8+ T cell responses in HLA-A transgenic mice

H. Qiu, Yuxian He, Guangyu Zhao, 2021, Cellular & Molecular Immunology.

Cross-Neutralization of Human and Palm Civet Severe Acute Respiratory Syndrome Coronaviruses by Antibodies Targeting the Receptor-Binding Domain of Spike Protein

Shibo Jiang, Wenhui Li, Shibo Jiang, 2006, The Journal of Immunology.

Distinct origins and functions of cardiac orthotopic macrophages

Yuxian He, Jiawei Zhong, Liang-rong Zheng, 2020, Basic Research in Cardiology.

Severe Fever with Thrombocytopenia Virus Glycoproteins Are Targeted by Neutralizing Antibodies and Can Use DC-SIGN as a Receptor for pH-Dependent Entry into Human and Animal Cell Lines

F. Weber, S. Pöhlmann, H. Hofmann, 2013, Journal of Virology.

The spike protein of SARS-CoV — a target for vaccine and therapeutic development

Shibo Jiang, L. Du, Shuwen Liu, 2009, Nature Reviews Microbiology.

Recombinant receptor-binding domain of SARS-CoV spike protein expressed in mammalian, insect and E. coli cells elicits potent neutralizing antibody and protective immunity

Shibo Jiang, L. Du, Yusen Zhou, 2009, Virology.

Defective HIV-1 envelope gene promotes the evolution of the infectious strain through recombination in vitro

Yuxian He, Xiuzhu Geng, Danwei Yu, 2020, BMC Infectious Diseases.

Structural Basis of Potent and Broad HIV-1 Fusion Inhibitor CP32M*

Yuxian He, Zonglin Qiu, Meitian Wang, 2012, The Journal of Biological Chemistry.

The V1/V2 Domain of gp120 Is a Global Regulator of the Sensitivity of Primary Human Immunodeficiency Virus Type 1 Isolates to Neutralization by Antibodies Commonly Induced upon Infection

S. Zolla-Pazner, M. Gorny, Yuxian He, 2004, Journal of Virology.

Protocol for evaluating CD8+ T cell-mediated immunity in latently SHIV-infected rhesus macaques with HIV fusion-inhibitory lipopeptide monotherapy

Yuxian He, Q. Wei, Z. Cong, 2022, STAR protocols.

Antigenic and Immunogenic Characterization of Recombinant Baculovirus-Expressed Severe Acute Respiratory Syndrome Coronavirus Spike Protein: Implication for Vaccine Design

Shibo Jiang, S. Heck, Shibo Jiang, 2006, Journal of Virology.

SARS vaccine development.

Shibo Jiang, Shibo Jiang, Shuwen Liu, 2005, Emerging infectious diseases.

Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4.

Asim Kumar Debnath, Shibo Jiang, Nouri Neamati, 2005, Virology.

Preparation and evaluation of amphipathic lipopeptide‐loaded PLGA microspheres as sustained‐release system for AIDS prevention

G. Ma, Yuxian He, Yi Wei, 2020, Engineering in life sciences.

A Membrane-Anchored Short-Peptide Fusion Inhibitor Fully Protects Target Cells from Infections of Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus

Yue Chen, Yuxian He, Li Li, 2019, Journal of Virology.

Recombinant Ov-ASP-1, a Th1-Biased Protein Adjuvant Derived from the Helminth Onchocerca volvulus, Can Directly Bind and Activate Antigen-Presenting Cells

N. A. Libri, S. Heck, S. Hartmann, 2009, The Journal of Immunology.

Activate Antigen-Presenting Cells , Can Directly Bind and Onchocerca volvulus Protein Adjuvant Derived from the Helminth-ASP-1 , a Th 1-Biased Ov Recombinant

N. A. Libri, S. Heck, S. Hartmann, 2009 .

Commonly Induced upon Infection Isolates to Neutralization by Antibodies Human Immunodeficiency Virus Type 1 Regulator of the Sensitivity of Primary The V 1 / V 2 Domain of gp 120 Is a Global

S. Zolla-Pazner, M. Gorny, Yuxian He, 2004 .

Efficient Isolation of Novel Human Monoclonal Antibodies with Neutralizing Activity Against HIV-1 from Transgenic Mice Expressing Human Ig Loci1

Yuxian He, A. Pinter, M. Burkhart, 2002, The Journal of Immunology.

Association of Autism Spectrum Disorder, Neuroticism, and Subjective Well-Being With Cardiovascular Diseases: A Two-Sample Mendelian Randomization Study

Yuxian He, Liangrong Zheng, Zhen Wang, 2021, Frontiers in Cardiovascular Medicine.

A single amino acid substitution (R441A) in the receptor-binding domain of SARS coronavirus spike protein disrupts the antigenic structure and binding activity

Shibo Jiang, Shibo Jiang, Yuxian He, 2006, Biochemical and Biophysical Research Communications.

Identification of a critical neutralization determinant of severe acute respiratory syndrome (SARS)-associated coronavirus: importance for designing SARS vaccines

Baoan Yang, Shibo Jiang, Qingyu Zhu, 2005, Virology.

The impact of plasma vitamin C levels on the risk of cardiovascular diseases and Alzheimer's disease: A Mendelian randomization study.

Yuxian He, Liangrong Zheng, Zhen Wang, 2021, Clinical nutrition.

Mapping of Antigenic Sites on the Nucleocapsid Protein of the Severe Acute Respiratory Syndrome Coronavirus

Shibo Jiang, Shuwen Liu, Yusen Zhou, 2004, Journal of Clinical Microbiology.

Vaccine design for severe acute respiratory syndrome coronavirus.

Shibo Jiang, Shibo Jiang, Yuxian He, 2005, Viral immunology.

Design and characterization of novel SARS-CoV-2 fusion inhibitors with N-terminally extended HR2 peptides

Yuxian He, Xiaohui Ju, Yuanmei Zhu, 2023, Antiviral Research.

Design and Characterization of Cholesterylated Peptide HIV-1/2 Fusion Inhibitors with Extremely Potent and Long-Lasting Antiviral Activity

Yusen Zhou, Yuxian He, Yan Guo, 2019, Journal of Virology.

Structural and functional characterization of HIV-1 cell fusion inhibitor T20

Xinquan Wang, Yuxian He, Xiaohui Ding, 2019, AIDS.

Design of Novel HIV-1/2 Fusion Inhibitors with High Therapeutic Efficacy in Rhesus Monkey Models

C. Qin, Yusen Zhou, Yuxian He, 2018, Journal of Virology.

Exceptional potency and structural basis of a T1249-derived lipopeptide fusion inhibitor against HIV-1, HIV-2, and simian immunodeficiency virus

Xinquan Wang, Yuxian He, Xiaohui Ding, 2018, The Journal of Biological Chemistry.

Development of potent and long-acting HIV-1 fusion inhibitors

Yuxian He, Yang Su, Hui-hui Chong, 2016, AIDS.

Synthesized peptide inhibitors of HIV-1 gp41-dependent membrane fusion.

Yuxian He, 2013, Current pharmaceutical design.

Conserved Salt Bridge between the N- and C-Terminal Heptad Repeat Regions of the Human Immunodeficiency Virus Type 1 gp41 Core Structure Is Critical for Virus Entry and Inhibition

A. Debnath, Hong Lu, Shibo Jiang, 2008, Journal of Virology.

A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement

Yusen Zhou, Yuxian He, Yansong Sun, 2010, Virology Journal.

Cross-reactive neutralization of SARS-CoV-2 by serum antibodies from recovered SARS patients and immunized animals

L. Ren, Jianwei Wang, Yuxian He, 2020, Science Advances.

Identification of SARS-CoV RBD-targeting monoclonal antibodies with cross-reactive or neutralizing activity against SARS-CoV-2

Shibo Jiang, L. Du, Wanbo Tai, 2020, Antiviral Research.

Longitudinal profiles of immunoglobulin G antibodies against severe acute respiratory syndrome coronavirus components and neutralizing activities in recovered patients

Yuxian He, Taisheng Li, H. Fan, 2011, Scandinavian journal of infectious diseases.

Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines

K. Yuen, Shibo Jiang, Jian-Dong Huang, 2006, Virology.

Identification and characterization of novel neutralizing epitopes in the receptor-binding domain of SARS-CoV spike protein: Revealing the critical antigenic determinants in inactivated SARS-CoV vaccine

Shibo Jiang, Xuxia Yan, Shibo Jiang, 2006, Vaccine.

A novel assay to identify entry inhibitors that block binding of HIV-1 gp120 to CCR5.

A. Debnath, Yuxian He, G. Alespeiti, 2004, Virology.

Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy

Shibo Jiang, Yusen Zhou, Yuxian He, 2020, bioRxiv.

Stability Analysis of a Typical Salt Cavern Gas Storage in the Jintan Area of China

Guangjie Yuan, Yuxian He, M. Jurado, 2022, Energies.

Numerical Study of Casing Microleakage Flow Field Sensitivity and Acoustic Field Characteristics

Yuxian He, Jifang Wan, Xinbo Zhao, 2022, Materials.

Obstructive sleep apnea and atrial fibrillation: insights from a bidirectional Mendelian randomization study

Yuxian He, Liangrong Zheng, Yunlong Lu, 2022, BMC Medical Genomics.

Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket

Hao Hu, Xinquan Wang, Yuxian He, 2018, Front. Cell. Infect. Microbiol..

Mechanism of HIV-1 Resistance to an Electronically Constrained α-Helical Peptide Membrane Fusion Inhibitor

Yuxian He, Xiaohui Ding, Yuanmei Zhu, 2018, Journal of Virology.

Broad Antiviral Activity and Crystal Structure of HIV-1 Fusion Inhibitor Sifuvirtide*

Yuxian He, Meitian Wang, Hui-hui Chong, 2012, The Journal of Biological Chemistry.

Highly pathogenic avian influenza A virus H5N1 NS1 protein induces caspase-dependent apoptosis in human alveolar basal epithelial cells

Yuxian He, Hongbin Song, Yutao Yang, 2010, Virology Journal.

Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy.

A. Perelson, B. Korber, D. Ho, 1999, The New England journal of medicine.

Isolation and characterization of a novel neutralizing antibody targeting the CD4-binding site of HIV-1 gp120.

Y. Qiao, Yuxian He, Zonglin Qiu, 2016, Antiviral research.

Evaluation of recombinant Onchocerca volvulus activation associated protein-1 (ASP-1) as a potent Th1-biased adjuvant with a panel of protein or peptide-based antigens and commercial inactivated vaccines.

Shibo Jiang, J. Guan, L. Du, 2008, Vaccine.

Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide

Yuxian He, Q. Wei, Z. Cong, 2021, Cell.

Discovery of Critical Residues for Viral Entry and Inhibition through Structural Insight of HIV-1 Fusion Inhibitor CP621–652*

Yuxian He, Zonglin Qiu, Meitian Wang, 2012, The Journal of Biological Chemistry.

Susceptibility and Resistance of SARS-CoV-2 Variants to LCB1 and Its Multivalent Derivatives

Yuxian He, Lin Cheng, Yuanmei Zhu, 2023, Viruses.

Characterization of novel HIV fusion-inhibitory lipopeptides with the M-T hook structure.

Yuxian He, Yuanmei Zhu, Hui-hui Chong, 2024, Microbes and infection.

Broad-spectrum anti-HIV activity and high drug resistance barrier of lipopeptide HIV fusion inhibitor LP-19

H. Xing, K. Hong, Liying Ma, 2023, Frontiers in Immunology.

The M-T hook structure increases the potency of HIV-1 fusion inhibitor sifuvirtide and overcomes drug resistance.

Y. Qiao, Jianping Sun, Yuxian He, 2014, The Journal of antimicrobial chemotherapy.

A novel trifunctional IgG-like bispecific antibody to inhibit HIV-1 infection and enhance lysis of HIV by targeting activation of complement

Yusen Zhou, Yuxian He, Yansong Sun, 2010, Virology Journal.

Construction of human combinatorial antibody library and screening of monoclonal antibody Fabs to human immunodeficiency virus type I

P. Tien, Xiyun Yan, Yuxian He, 1999 .