S. Abrignani

P. Stanzione, G. Simonetti, S. Abrignani, 2014, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists.

Presence of Effector CD 8 1 T Cells in Hepatitis C Virus-Exposed Healthy Seronegative Donors 1

J. Sidney, A. Sette, D. Accapezzato, 1999 .

26 – Hepatitis C Vaccines

M. Houghton, R. Francesco, S. Abrignani, 2018 .

Why is it so difficult to develop a hepatitis C virus preventive vaccine?

R. De Francesco, S. Abrignani, C. Zingaretti, 2014, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

48 – Hepatitis C vaccines

M. Houghton, R. Francesco, S. Abrignani, 2012 .

Prospects for a vaccine against the hepatitis C virus

M. Houghton, S. Abrignani, 2005, Nature.

A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells.

M. Houghton, A. Weiner, Q. Choo, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Recombinant human monoclonal antibodies against different conformational epitopes of the E2 envelope glycoprotein of hepatitis C virus that inhibit its interaction with CD81.

A. Widell, M. Houghton, S. Abrignani, 2000, The Journal of general virology.

Human Monoclonal Antibodies That Inhibit Binding of Hepatitis C Virus E2 Protein to CD81 and Recognize Conserved Conformational Epitopes

S. Levy, R. Lanford, P. Pileri, 2000, Journal of Virology.

Characterization of antibodies induced by vaccination with Hepatitis C virus envelope glycoproteins

K. Meyer, R. Ray, M. Houghton, 2010, The Journal of infectious diseases.

Dissection of human humoral immune response against hepatitis C virus E2 glycoprotein by repertoire cloning and generation of recombinant fab fragments

G. Fadda, S. Abrignani, M. Clementi, 1998, Hepatology.

Identification of New Hematopoietic Cell Subsets with a Polyclonal Antibody Library Specific for Neglected Proteins

M. Marconi, P. Rebulla, G. Viale, 2012, PloS one.

Gaps in knowledge and prospects for research of adjuvanted vaccines.

S. Bertholet, S. Reed, L. Steinman, 2015, Vaccine.

Inexplicable Late Type Ia Endoleak Associated With the Low-Profile Ovation Endograft in a Patient With Favorable Neck Anatomy

G. Simonetti, S. Abrignani, R. Gandini, 2015, Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists.

CCR6 is expressed on an IL-10–producing, autoreactive memory T cell population with context-dependent regulatory function

C. Loddenkemper, D. Jarrossay, F. Sallusto, 2010, The Journal of experimental medicine.

Structure-Function Analysis of Hepatitis C Virus Envelope-CD81 Binding

M. Houghton, G. Grandi, R. Petracca, 2000, Journal of virology.

Identification of New Autoantigens by Protein Array Indicates a Role for IL4 Neutralization in Autoimmune Hepatitis*

F. Marabita, M. Marconi, P. Marcatili, 2012, Molecular & Cellular Proteomics.

Novel biomarkers for primary biliary cholangitis to improve diagnosis and understand underlying regulatory mechanisms

L. Terracciano, A. Torri, R. Grifantini, 2019, Liver international : official journal of the International Association for the Study of the Liver.

Lack of evidence for post-vaccine onset of autoimmune/lymphoproliferative disorders, during a nine-month follow-up in multiply vaccinated Italian military personnel.

J. Sidney, A. Sette, C. Martire, 2017, Clinical immunology.

The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.

R. Müller, S. Gallo, S. Ricciardi, 2018, Cell metabolism.

N-glycosylation of HIV-gp120 may constrain recognition by T lymphocytes.

N. Haigwood, B. Houlden, C. Servis, 1991, Journal of immunology.

Rationally designed strings of promiscuous CD4+ T cell epitopes provide help to Haemophilus influenzae type b oligosaccharide: a model for new conjugate vaccines

R. Rappuoli, G. Grandi, M. Melli, 2001, European journal of immunology.

Echinococcosis, Ningxia, China

B. Murphy, R. Rappuoli, H. Klenk, 2019 .

SARS Vaccine Protective in Mice

B. Murphy, R. Rappuoli, H. Klenk, 2005, Emerging infectious diseases.

IL-10-producing forkhead box protein 3-negative regulatory T cells inhibit B-cell responses and are involved in systemic lupus erythematosus.

A. Annoni, R. Flavell, L. Pignataro, 2016, The Journal of allergy and clinical immunology.

Sexual transmission of hepatitis C virus and prevention with intramuscular immunoglobulin.

M. Stazi, S. Abrignani, M. Clementi, 1998, AIDS patient care and STDs.

Treatment of Symptomatic High-Flow Female Varicoceles with Stop-flow Foam Sclerotherapy

G. Simonetti, S. Abrignani, V. Da Ros, 2014, CardioVascular and Interventional Radiology.

Immunosuppressant Treatment in Rheumatic Musculoskeletal Diseases Does Not Inhibit Elicitation of Humoral Response to SARS-CoV-2 Infection and Preserves Effector Immune Cell Populations

Lara Manganaro, R. De Francesco, E. Marchisio, 2022, Frontiers in Immunology.

Helicobacter pylori-specific CD4+ T-cell clones from peripheral blood and gastric biopsies

R. Rappuoli, R. Rappuoli, P. Pileri, 1995, Infection and immunity.

Differentiation of Uncommitted Human T Control Cytokine-Induced Th 17 Signal Strength and Metabolic Requirements

S. Abrignani, M. Moro, M. Crosti, 2015 .

Signal Strength and Metabolic Requirements Control Cytokine-Induced Th17 Differentiation of Uncommitted Human T Cells

S. Abrignani, J. Geginat, M. Moro, 2015, The Journal of Immunology.

Analysis RNA-seq and Noncoding RNA.

V. Ranzani, S. Abrignani, R. Bonnal, 2016, Methods in molecular biology.

Next-Generation Sequencing Analysis of Long Noncoding RNAs in CD4+ T Cell Differentiation.

V. Ranzani, S. Abrignani, R. Bonnal, 2017, Methods in molecular biology.

Virus‐specific CD8+ T cells with type 1 or type 2 cytokine profile are related to different disease activity in chronic hepatitis C virus infection

A. Sette, V. Barnaba, S. Abrignani, 2001, European journal of immunology.

Hepatitis C virus envelope glycoprotein immunization of rodents elicits cross-reactive neutralizing antibodies.

C. Rice, M. Houghton, M. J. Evans, 2007, Vaccine.

Evaluation of Hepatitis C Virus Glycoprotein E2 for Vaccine Design: an Endoplasmic Reticulum-Retained Recombinant Protein Is Superior to Secreted Recombinant Protein and DNA-Based Vaccine Candidates

M. Houghton, G. Bensi, S. Coates, 2000, Journal of Virology.

T cells can present antigens such as HIV gp120 targeted to their own surface molecules

A. Lanzavecchia, P. Berman, S. Abrignani, 1988, Nature.

Immunological variables associated with clinical and endoscopic response to vedolizumab in patients with inflammatory bowel diseases.

S. Abrignani, E. Rulli, J. Geginat, 2020, Journal of Crohn's & colitis.

PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity

N. Divecha, S. Abrignani, M. Pagani, 2021, Proceedings of the National Academy of Sciences.

Characterization of human monoclonal antibodies specific to the hepatitis C virus glycoprotein E2 with in vitro binding neutralization properties.

J. Dubuisson, C. Wychowski, C. Trépo, 1998, Virology.

Modulation of the Immune Response to the Severe Acute Respiratory Syndrome Spike Glycoprotein by Gene-Based and Inactivated Virus Immunization

Gary J. Nabel, Ling Xu, Rino Rappuoli, 2005, Journal of Virology.

Phylogeny of the SARS Coronavirus

C. Donati, R. Rappuoli, H. Doerr, 2003, Science.

Early Intervention in preterm infants modulates LINE-1 promoter methylation and neurodevelopment

S. Lodato, Camilla Fontana, N. Pesenti, 2019, medRxiv.

CD1d-restricted Help To B Cells By Human Invariant Natural Killer T Lymphocytes

S. Nuti, S. Abrignani, P. Dellabona, 2003, The Journal of experimental medicine.

Antigen-independent activation of naive and memory resting T cells by a cytokine combination

P. Pileri, S. Abrignani, D. Unutmaz, 1994, The Journal of experimental medicine.

T cell costimulation by the hepatitis C virus envelope protein E2 binding to CD81 is mediated by Lck

C. Baldari, C. Ulivieri, U. D'Oro, 2003, European journal of immunology.

Expression of human CD81 in transgenic mice does not confer susceptibility to hepatitis C virus infection.

M. Houghton, S. Levy, M. Bendinelli, 2002, Virology.

Vδ1T Lymphocytes Expressing a Th1 Phenotype Are the Major γδ T Cell Subset Infiltrating the Liver of HCV-infected Persons

C. Agrati, P. Narciso, G. Ippolito, 2001, Molecular medicine.

Eomesodermin controls a unique differentiation program in human IL‐10 and IFN‐γ coproducing regulatory T cells

V. Ranzani, Martina Martinovic, F. Locatelli, 2018, European journal of immunology.

Differences in serum and synovial CD4+ T cells and cytokine profiles to stratify patients with inflammatory osteoarthritis and rheumatoid arthritis

M. Truzzi, P. Meroni, S. Abrignani, 2017, Arthritis Research & Therapy.

IL‐10 promotes homeostatic proliferation of human CD8+ memory T cells and, when produced by CD1c+ DCs, shapes naive CD8+ T‐cell priming

R. Francesco, S. Abrignani, J. Geginat, 2016, European journal of immunology.

Immunity to Pathogens Taught by Specialized Human Dendritic Cell Subsets

S. Abrignani, J. Geginat, S. Pascolo, 2015, Front. Immunol..

NS5A Inhibitors Impair NS5A–Phosphatidylinositol 4-Kinase IIIα Complex Formation and Cause a Decrease of Phosphatidylinositol 4-Phosphate and Cholesterol Levels in Hepatitis C Virus-Associated Membranes

R. De Francesco, V. Berno, S. Abrignani, 2014, Antimicrobial Agents and Chemotherapy.

The small extracellular loop of CD81 is necessary for optimal surface expression of the large loop, a putative HCV receptor.

Y. Uematsu, P. Pileri, S. Abrignani, 2001, Virus research.

DNA-Based Vaccine Candidates Secreted Recombinant Protein and Recombinant Protein Is Superior to Endoplasmic Reticulum-Retained Glycoprotein E 2 for Vaccine Design : an Evaluation of Hepatitis C Virus

M. Houghton, G. Bensi, G. Grandi, 2000 .

High titers of antibodies inhibiting the binding of envelope to human cells correlate with natural resolution of chronic hepatitis C

M. Houghton, Colby A. Wyatt, K. Ishii, 1998, Hepatology.

Formaldehyde treatment of proteins can constrain presentation to T cells by limiting antigen processing

R. Rappuoli, S. Abrignani, M. Bugnoli, 1994, Infection and immunity.

Deep Phenotyping of T-Cells Derived From the Aneurysm Wall in a Pediatric Case of Subarachnoid Hemorrhage

N. Stocchetti, S. Abrignani, J. Geginat, 2022, Frontiers in Immunology.

Human CD1c 1 dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses

C. Scheibenbogen, R. Francesco, L. Pignataro, 2013 .

prime cytotoxic T-cell responses dendritic cells secrete high levels of IL-12 and potently + Human CD1c

C. Scheibenbogen, L. Pignataro, Jana Krietsch, 2013 .

Vaccination Against the Hepatitis C Virus

M. Houghton, R. Francesco, S. Abrignani, 2009 .

Human naive T cells activated by cytokines differentiate into a split phenotype with functional features intermediate between naive and memory T cells.

S. Abrignani, D. Unutmaz, F. Baldoni, 1995, International immunology.

Safety and immunogenicity of a genetically engineered human immunodeficiency virus vaccine.

K. Steimer, C. Chaignat, J. Dayer, 1991, The Journal of infectious diseases.

Priming of CD4+ T cells specific for conserved regions of human immunodeficiency virus glycoprotein gp120 in humans immunized with a recombinant envelope protein.

K. Steimer, N. Haigwood, S. Abrignani, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders.

M. Houghton, V. Barnaba, E. De Gregorio, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Binding of Hepatitis C Virus Envelope Protein E2 to CD81 Up-regulates Matrix Metalloproteinase-2 in Human Hepatic Stellate Cells*

L. Cosmi, F. Annunziato, V. Carloni, 2005, Journal of Biological Chemistry.

Anti-Phospholipid Antibodies and Coronavirus Disease 2019: Vaccination Does Not Trigger Early Autoantibody Production in Healthcare Workers

G. Parati, R. Grifantini, M. Bombaci, 2022, Frontiers in Immunology.

Cytoskeleton rearrangement induced by tetraspanin engagement modulates the activation of T and NK cells

C. Baldari, C. Ulivieri, S. Abrignani, 2006, European journal of immunology.

Nonneutralizing human antibody fragments against hepatitis C virus E2 glycoprotein modulate neutralization of binding activity of human recombinant Fabs.

G. Fadda, S. Abrignani, M. Clementi, 2001, Virology.

Structure-Function Analysis of Hepatitis C Virus Envelope-CD 81 Binding

M. Houghton, G. Grandi, R. Petracca, 2000 .

Prospects for a hepatitis C virus vaccine.

M. Houghton, S. Abrignani, H. Hsu, 1999, Clinics in liver disease.

HCV E1E2-MF59 vaccine in chronic hepatitis C patients treated with PEG-IFNα2a and Ribavirin: a randomized controlled trial

R. Rappuoli, M. Houghton, M. Mondelli, 2013, Journal of viral hepatitis.

Neonatal invariant Vα24+ NKT lymphocytes are activated memory cells

S. Abrignani, P. Dellabona, A. Moretta, 2000 .

IL-10 producing regulatory and helper T-cells in systemic lupus erythematosus.

R. Flavell, S. Abrignani, J. Geginat, 2019, Seminars in immunology.

iNKT‐cell help to B cells: A cooperative job between innate and adaptive immune responses

S. Abrignani, P. Dellabona, G. Casorati, 2014, European journal of immunology.

The light and the dark sides of Interleukin-10 in immune-mediated diseases and cancer.

R. Flavell, P. Meroni, S. Abrignani, 2016, Cytokine & growth factor reviews.

Antibodies as antigens. The use of mouse monoclonal antibodies to focus human T cells against selected targets

B. Dörken, A. Lanzavecchia, S. Abrignani, 1988, The Journal of experimental medicine.

Multi‐plasmid DNA vaccination avoids antigenic competition and enhances immunogenicity of a poorly immunogenic plasmid

A. Thomas, G. Grandi, R. Grifantini, 1998, European journal of immunology.

Innate immune responses support adaptive immunity: NKT cells induce B cell activation.

S. Nuti, S. Abrignani, P. Dellabona, 2003, Vaccine.

Complement activation by cell-associated immune complexes in contact sensitivity.

G. Asherson, F. Dieli, A. Salerno, 1984, Cellular immunology.

Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4+ T Cell Help

U. V. von Andrian, S. Abrignani, P. Dellabona, 2012, The Journal of Immunology.

NKT-cell help to B lymphocytes can occur independently of cognate interaction.

S. Abrignani, P. Dellabona, G. Casorati, 2009, Blood.

B cell helper assays.

S. Abrignani, P. Dellabona, G. Casorati, 2009, Methods in molecular biology.

T suppressor afferent cells which regulate contact sensitivity to picryl chloride act across genetic barrier.

F. Dieli, A. Salerno, S. Abrignani, 1986, Immunology letters.

Evaluation of humoral and cellular response to four vaccines against COVID-19 in different age groups: A longitudinal study

S. Merler, F. Trentini, G. Antonelli, 2022, Frontiers in Immunology.

Antigen-independent activation of resting T-cells in the liver of patients with chronic hepatitis.

S. Abrignani, 1998, Developments in biological standardization.

The Hepatitis C Virus: Genetic Organization, Persistence, and Vaccine Strategies

B. Walker, M. Houghton, A. Weiner, 1994 .

Human T lymphocytes at tumor sites

S. Abrignani, S. Notarbartolo, Samuele Notarbartolo, 2022, Seminars in Immunopathology.

Safety and immunogenicity of HCV E1E2 vaccine adjuvanted with MF59 administered to healthy adults.

R. Ray, M. Houghton, R. Belshe, 2010, Vaccine.

Perspectives for a hepatitis C virus vaccine.

S. Abrignani, D. Rosa, 1998, Clinical and diagnostic virology.

Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant

G. Dougan, R. Rappuoli, M. Pizza, 1996, Infection and immunity.

Comparable functions of plasmacytoid and monocyte-derived dendritic cells in chronic hepatitis C patients and healthy donors.

M. Brunetto, S. Nuti, S. Abrignani, 2005, Journal of hepatology.

Third trimester NG2-positive amniotic fluid cells are effective in improving repair in spinal cord injury

A. Gorio, S. Abrignani, D. Bottai, 2014, Experimental Neurology.

Evidence for a pathogenic role of extrafollicular, IL-10–producing CCR6+B helper T cells in systemic lupus erythematosus

R. Flavell, V. Ranzani, L. Pignataro, 2020, Proceedings of the National Academy of Sciences.

DITTO-HCV early viral kinetics report - novel decline patterns in gen 1 but not gen 2–3 patients treated with PEG-interferon-alfa-2a and ribavirin

A. Neumann, J. Pawlotsky, F. Negro, 2002 .

Mapping of functional SARS-CoV-2 receptors in human lungs establishes differences in variant binding and SLC1A5 as a viral entry modulator of hACE2

R. De Francesco, S. Ricciardi, S. Biffo, 2022, eBioMedicine.

Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses.

C. Scheibenbogen, R. De Francesco, L. Pignataro, 2013, Blood.

Sexual transmission of the hepatitis C virus and efficacy of prophylaxis with intramuscular immune serum globulin. A randomized controlled trial.

M. Stazi, S. Abrignani, M. Clementi, 1997, Archives of internal medicine.

Presence of effector CD8+ T cells in hepatitis C virus-exposed healthy seronegative donors.

A Sette, J Sidney, J. Sidney, 1999, Journal of immunology.

The Impact of Anti-rheumatic Drugs on the Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Cohort of Patients With Inflammatory Arthritis: The MAINSTREAM Study

R. Caporali, E. Marchisio, R. Grifantini, 2022, Frontiers in Medicine.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Amit A. Patel, F. Ginhoux, D. Busch, 2021, European journal of immunology.

Exosomes Recovered From the Plasma of COVID-19 Patients Expose SARS-CoV-2 Spike-Derived Fragments and Contribute to the Adaptive Immune Response

R. De Francesco, S. Biffo, F. Blasi, 2022, Frontiers in Immunology.

SARS — beginning to understand a new virus

R. Rappuoli, H. Klenk, V. Masignani, 2003, Nature Reviews Microbiology.

High-dose vitamin C enhances cancer immunotherapy

Massimo Zucchetti, Francesco Sassi, Sergio Abrignani, 2020, Science Translational Medicine.

LINE1 are spliced in non-canonical transcript variants to regulate T cell quiescence and exhaustion

V. Ranzani, S. Harari, G. Viale, 2022, Nature Genetics.

Inhibition of lymphocyte mitogenesis in mice infected with Newcastle disease virus: viral interference with the interleukin system.

F. Dieli, A. Salerno, S. Abrignani, 1986, Immunology.

Infection of mice with Newcastle disease virus inhibits the T suppressor afferent cell circuit which regulates contact sensitivity to picryl chloride.

F. Dieli, A. Salerno, S. Abrignani, 1985, Cellular immunology.

A Hepatitis C Virus (HCV) Vaccine Comprising Envelope Glycoproteins gpE1/gpE2 Derived from a Single Isolate Elicits Broad Cross-Genotype Neutralizing Antibodies in Humans

Christopher T. Jones, C. Rice, J. Bukh, 2013, PloS one.

Invariant NKT cells sustain specific B cell responses and memory

R. Rappuoli, O. Finco, S. Nuti, 2007, Proceedings of the National Academy of Sciences.

IL28B polymorphisms predict interferon‐related hepatitis B surface antigen seroclearance in genotype D hepatitis B e antigen–negative patients with chronic hepatitis B

R. De Francesco, P. Lampertico, C. Cheroni, 2013, Hepatology.

Production of Profibrotic Cytokines by Invariant NKT Cells Characterizes Cirrhosis Progression in Chronic Viral Hepatitis1

F. Callea, S. Nuti, S. Porcelli, 2004, The Journal of Immunology.

Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C

M. Houghton, M. Brunetto, P. Pileri, 1993, The Journal of experimental medicine.

Genetic variation in the interleukin‐28B gene is not associated with fibrosis progression in patients with chronic hepatitis C and known date of infection

F. Marabita, R. De Francesco, C. Cheroni, 2011, Hepatology.

Circulating Hepatitis B Surface Antigen Particles Carry Hepatocellular microRNAs

M. Brunetto, S. Abrignani, M. Pagani, 2012, PloS one.

Role of microRNAs and long‐non‐coding RNAs in CD4+ T‐cell differentiation

S. Abrignani, J. Geginat, M. Pagani, 2013, Immunological reviews.

Distinct microRNA signatures in human lymphocyte subsets and enforcement of the naive state in CD4+ T cells by the microRNA miR-125b

F. Marabita, R. Francesco, S. Abrignani, 2011, Nature Immunology.

Small Interfering RNA-Mediated Inhibition of Hepatitis C Virus Replication in the Human Hepatoma Cell Line Huh-7

M. Houghton, Mi-young Seo, S. Abrignani, 2003, Journal of Virology.

Exploring the links between cancer and placenta development

A. Bardelli, V. Costanzo, S. Abrignani, 2018, Open Biology.

Reduction of CD68+ Macrophages and Decreased IL-17 Expression in Intestinal Mucosa of Patients with Inflammatory Bowel Disease Strongly Correlate With Endoscopic Response and Mucosal Healing following Infliximab Therapy

D. Conte, S. Abrignani, M. Pagani, 2013, Inflammatory bowel diseases.

Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors are associated with disease progression

A. Bardelli, G. Veronesi, M. Alloisio, 2021, Nature Immunology.

Intestinal IFN‐&ggr;–producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL‐10 in the inflamed guts of patients with inflammatory bowel disease

R. Flavell, V. Ranzani, S. Abrignani, 2018, The Journal of allergy and clinical immunology.

Long Intergenic Non-Coding RNAs: Novel Drivers of Human Lymphocyte Differentiation

S. Abrignani, M. Pagani, G. Rossetti, 2015, Front. Immunol..

Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors.

Simona Baghai Sain, S. A. van de Pavert, F. Bernassola, 2022, Immunity.

A Subset of Colorectal Cancers with Cross-Sensitivity to Olaparib and Oxaliplatin

A. Bardelli, C. Isella, E. Medico, 2019, Clinical Cancer Research.

The Enigmatic Role of Viruses in Multiple Sclerosis: Molecular Mimicry or Disturbed Immune Surveillance?

D. Galimberti, E. Scarpini, R. De Francesco, 2017, Trends in Immunology.

Hepatitis C virus polyprotein vaccine formulations capable of inducing broad antibody and cellular immune responses.

M. Houghton, Manmohan J. Singh, S. Coates, 2006, The Journal of general virology.

Genetic and pharmacological modulation of DNA mismatch repair heterogeneous tumors promotes immune surveillance

A. Bardelli, S. Marsoni, F. Di Nicolantonio, 2022, Cancer cell.

miRiadne: a web tool for consistent integration of miRNA nomenclature

Raoul Jean Pierre Bonnal, Riccardo L. Rossi, Sergio Abrignani, 2015, Nucleic Acids Res..

Dynamics of intra‐hepatic lymphocytes in chronic hepatitis C: enrichment for Vα24+ T cells and rapid elimination of effector cells by apoptosis

V. Barnaba, S. Nuti, S. Abrignani, 1998, European journal of immunology.

Coligation of the Hepatitis C Virus Receptor CD81 with CD28 Primes Naive T Lymphocytes to Acquire Type 2 Effector Function1

A. Serra, S. Nuti, S. Abrignani, 2008, The Journal of Immunology.

CombiROC: an interactive web tool for selecting accurate marker combinations of omics data

Saveria Mazzara, Mauro Bombaci, Riccardo L. Rossi, 2017, Scientific Reports.

Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity

R. De Francesco, S. Abrignani, M. Pagani, 2012, PLoS pathogens.

Hepatic expansion of a virus-specific regulatory CD8+ T cell population in chronic hepatitis C virus infection

D. Accapezzato, V. Barnaba, M. Mondelli, 2004 .

Integrated longitudinal immunophenotypic, transcriptional and repertoire analyses delineate immune responses in COVID-19 patients.

A. Lanzavecchia, R. De Francesco, V. Ranzani, 2021, Science immunology.

Maturation signatures of conventional dendritic cell subtypes in COVID‐19 suggest direct viral sensing

F. Granucci, R. Spreafico, V. Ranzani, 2021, European journal of immunology.

Maturation signatures of conventional dendritic cells in COVID-19 reflect direct viral sensing

F. Granucci, R. Spreafico, V. Ranzani, 2021, bioRxiv.

IL-21 Is a Central Memory T Cell–Associated Cytokine That Inhibits the Generation of Pathogenic Th1/17 Effector Cells

S. Abrignani, J. Geginat, C. Romagnani, 2014, The Journal of Immunology.

Associated Cytokine That Inhibits the - IL-21 Is a Central Memory T Cell

S. Abrignani, J. Geginat, C. Romagnani, 2014 .

The CD4-centered universe of human T cell subsets.

S. Abrignani, J. Geginat, M. Pagani, 2013, Seminars in immunology.

Early maternal care restores LINE-1 methylation and enhances neurodevelopment in preterm infants

S. Lodato, Camilla Fontana, N. Pesenti, 2021, BMC Medicine.

Two of Them Do It Better: Novel Serum Biomarkers Improve Autoimmune Hepatitis Diagnosis

Saveria Mazzara, Sergio Abrignani, M. Bombaci, 2015, PloS one.

Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection.

D. Accapezzato, V. Barnaba, M. Mondelli, 2004, The Journal of clinical investigation.

Folding and dimerization of hepatitis C virus E1 and E2 glycoproteins in stably transfected CHO cells.

A. Helenius, M. Houghton, S. Abrignani, 2005, Virology.

Hepatitis C Virus Deletion Mutants Are Found in Individuals Chronically Infected with Genotype 1 Hepatitis C Virus in Association with Age, High Viral Load and Liver Inflammatory Activity

R. De Francesco, C. Cheroni, S. Abrignani, 2015, PloS one.

mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion

S. Biffo, S. Abrignani, A. Miluzio, 2021, eLife.

miR-17∼92 family clusters control iNKT cell ontogenesis via modulation of TGF-β signaling

P. Provero, E. Stupka, C. Xiao, 2016, Proceedings of the National Academy of Sciences.

The circulating microRNome demonstrates distinct lymphocyte subset‐dependent signatures

A. Torri, S. Abrignani, P. Dellabona, 2016, European journal of immunology.

De novo transcriptome profiling of highly purified human lymphocytes primary cells

V. Ranzani, S. Abrignani, R. Bonnal, 2015, Scientific Data.

Recognition of viral and self‐antigens by TH1 and TH1/TH17 central memory cells in patients with multiple sclerosis reveals distinct roles in immune surveillance and relapses

D. Galimberti, C. Fenoglio, E. Scarpini, 2017, The Journal of allergy and clinical immunology.

Lymphocytes to Acquire Type 2 Effector CD81 with CD28 Primes Naive T Coligation of the Hepatitis C Virus Receptor

S. Nuti, S. Abrignani, D. Rosa, 2013 .

Uncontrolled IL-17 Production by Intraepithelial Lymphocytes in a Case of non-IPEX Autoimmune Enteropathy

D. Conte, L. Elli, S. Abrignani, 2016, Clinical and Translational Gastroenterology.

Inhibition of Natural Killer Cells through Engagement of CD81 by the Major Hepatitis C Virus Envelope Protein

S. Nuti, S. Abrignani, M. Mosca, 2002, The Journal of experimental medicine.

Plasticity of Human CD4 T Cell Subsets

S. Abrignani, J. Geginat, M. Pagani, 2014, Front. Immunol..

Pulmonary Langerhans cell histiocystosis (PLCH) and lymphangioleiomyomatosis (LAM) have circulating cells with loss of heterozygosity of the TSC2 gene.

S. Harari, Joel Moss, S. Abrignani, 2022, Chest.

Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells

V. Ranzani, L. Pignataro, S. Abrignani, 2017, Proceedings of the National Academy of Sciences.

Ex vivo microRNA and gene expression profiling of human Tr1‐like cells suggests a role for miR‐92a and ‐125a in the regulation of EOMES and IL‐10R

V. Ranzani, S. Abrignani, J. Geginat, 2021, European journal of immunology.

Reverse plasticity: TGF‐β and IL‐6 induce Th1‐to‐Th17‐cell transdifferentiation in the gut

S. Abrignani, J. Geginat, M. Pagani, 2016, European journal of immunology.

Chlamydia pneumoniae genome sequence analysis and identification of HLA-A2-restricted CD8+ T cell epitopes recognized by infection-primed T cells.

G. Bensi, G. Grandi, O. Finco, 2005, Vaccine.

Binding of the hepatitis C virus envelope protein E2 to CD81 provides a co‐stimulatory signal for human T cells

S. Nuti, S. Abrignani, C. Tseng, 2001, European journal of immunology.

Third trimester amniotic fluid cells with the capacity to develop neural phenotypes and with heterogeneity among sub-populations.

A. D. Di Giulio, A. Gorio, S. Abrignani, 2012, Restorative neurology and neuroscience.

Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR

Jesper Tegnér, Francesco Marabita, Riccardo L. Rossi, 2015, Briefings Bioinform..

A novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins.

A. Pierleoni, R. Nogarotto, G. Grandi, 2011, Journal of proteomics.

Bystander activation by cytokines of intrahepatic T cells in chronic viral hepatitis.

S. Abrignani, 1997, Seminars in liver disease.

Impaired seroconversion after SARS-CoV-2 mRNA vaccines in patients with solid tumours receiving anticancer treatment

R. Grifantini, S. Abrignani, A. Sartore-Bianchi, 2021, European Journal of Cancer.

Serum microRNAs as Biomarkers of Human Lymphocyte Activation in Health and Disease

A. Torri, S. Abrignani, M. Pagani, 2014, Front. Immunol..

Intracellular Modulation, Extracellular Disposal and Serum Increase of MiR-150 Mark Lymphocyte Activation

Francesco Marabita, Fabio Mosca, Monica Moro, 2013, PloS one.

Evidence of blood-brain barrier alteration and activation in HIV-1 gp120 transgenic mice.

O. Finco, S. Abrignani, H. van der Putten, 1999, AIDS.

Extracellular MicroRNA Signature of Human Helper T Cell Subsets in Health and Autoimmunity*

G. Matarese, C. Tacchetti, V. Bollati, 2017, The Journal of Biological Chemistry.

The endless frontier? The recent increase of R&D productivity in pharmaceuticals

L. Pani, F. Pammolli, P. Pelicci, 2020, Journal of Translational Medicine.

Anti-spike antibodies and neutralising antibody activity in people living with HIV vaccinated with COVID-19 mRNA-1273 vaccine: a prospective single-centre cohort study

D. Consonni, S. Ludovisi, R. De Francesco, 2021, The Lancet Regional Health - Europe.

Association of hepatitis C virus envelope proteins with exosomes

M. Houghton, M. Brunetto, P. Pileri, 2004, European journal of immunology.

Flow diversion for indirect carotid-cavernous fistula: Still an off-label indication?

S. Abrignani, L. Brunasso, G. Giammalva, 2023, Surgical neurology international.

Immunization of human volunteers with hepatitis C virus envelope glycoproteins elicits antibodies that cross-neutralize heterologous virus strains.

M. Houghton, J. McKeating, Z. Stamataki, 2011, The Journal of infectious diseases.

Induction of CD4+ T cell depletion in mice doubly transgenic for HIV gp120 and human CD4

O. Finco, S. Nuti, S. Abrignani, 1997, European journal of immunology.

cell help , vaccines , T follicular helper cells

S. Abrignani, P. Dellabona, G. Casorati, 2014 .

Production of anti-PF4 antibodies in antiphospholipid antibody-positive patients is not affected by COVID-19 vaccination

Marcus John Beasley, A. Tincani, R. Grifantini, 2021, RMD Open.

Eomesodermin‐expressing type 1 regulatory (EOMES+Tr1)‐like T cells: Basic biology and role in immune‐mediated diseases

S. Abrignani, J. Geginat, M. Pagani, 2023, European journal of immunology.

Moving closer to a mouse model for hepatitis C

D. Burton, S. Abrignani, 2009, Nature Medicine.

Life, activation and death of intrahepatic lymphocytes in chronic hepatitis C

P. Klenerman, F. Lechner, S. Nuti, 2000, Immunological reviews.

Immune responses throughout hepatitis C virus (HCV) infection: HCV from the immune system point of view

S. Abrignani, 2004, Springer Seminars in Immunopathology.

Dual role of anti-TNF therapy: enhancement of TCR-mediated T cell activation in peripheral blood and inhibition of inflammation in target tissues.

Gianfranco Altomare, Sergio Abrignani, S. Abrignani, 2011, Clinical immunology.

The Endless Frontier? The Recent Upsurge of R&D Productivity in Pharmaceuticals

L. Pani, F. Pammolli, P. Pelicci, 2019, bioRxiv.

Role of macrophages in bypassing the inhibitory activity of Newcastle disease virus on the T-suppressor-cell circuit which regulates contact sensitivity to picryl chloride.

D. Lio, F. Dieli, A. Salerno, 1988, Cellular immunology.

Neonatal invariant Valpha24+ NKT lymphocytes are activated memory cells.

S. Abrignani, P. Dellabona, A. Moretta, 2000, European journal of immunology.

CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs

M. Bolognesi, G. Grandi, R. Petracca, 2001, The EMBO journal.

Molecular analysis of VHI+ B lymphocytes in hepatitis C patients

S. Abrignani, M. Mosca, F. Bonino, 2003 .

Trans-splenic Embolization Plus Partial Splenic Embolization for Management of Variceal Bleeding Due to Left-Sided Portal Hypertension

F. Chegai, S. Abrignani, I. Lenci, 2017, Digestive Diseases and Sciences.

Vaccines Against Human Hookworm Disease

S. Hoffman, D. Vaughn, R. Brunham, 2004 .

TMEM123 a key player in immune surveillance of colorectal cancer

G. Viale, S. Biffo, S. Eppenberger-Castori, 2023, Frontiers in Immunology.

Combiroc: when ‘less is more’ in bulk and single cell marker signatures

R. Grifantini, M. Bombaci, S. Abrignani, 2023, bioRxiv.

Intracellular accumulation of hepatitis C virus proteins in a human hepatoma cell line.

F. Bagnoli, S. Abrignani, M. Brazzoli, 2007, Journal of hepatology.

LincRNA landscape in human lymphocytes highlights regulation of T cell differentiation by linc-MAF-4

M. Marconi, R. De Francesco, V. Ranzani, 2014, Nature Immunology.

Repression of miR-31 by BCL6 stabilizes the helper function of human follicular helper T cells

V. Ranzani, S. Abrignani, J. Geginat, 2017, Proceedings of the National Academy of Sciences.

Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4+ T Cell Help

U. V. von Andrian, S. Abrignani, P. Dellabona, 2012, The Journal of Immunology.

The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling.

R. Müller, S. Gallo, S. Biffo, 2018, Cell metabolism.

The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling

R. Müller, S. Gallo, S. Biffo, 2018, Cell metabolism.

Endovascular Mechanical Thromboaspiration of Right Hepatic Arterial Thrombosis After Liver Transplantation

R. Floris, G. Tisone, S. Abrignani, 2017, CardioVascular and Interventional Radiology.

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Amit A. Patel, F. Ginhoux, D. Busch, 2021, European journal of immunology.

IL28B polymorphisms predict interferon‐related hepatitis B surface antigen seroclearance in genotype D hepatitis B e antigen–negative patients with chronic hepatitis B

P. Lampertico, C. Cheroni, S. Abrignani, 2013, Hepatology.

Immunity Resource Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells

G. Cesana, L. Gianotti, R. Francesco, 2017 .