D. Manickam

发表

Effect of cell membrane thiols and reduction-triggered disassembly on transfection activity of bioreducible polyplexes.

D. Oupický, Jing Li, D. Manickam, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Reducible poly(2-dimethylaminoethyl methacrylate): synthesis, cytotoxicity, and gene delivery activity.

D. Oupický, Yezi You, Qing-hui Zhou, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Effect of innate glutathione levels on activity of redox-responsive gene delivery vectors.

Chao Wu, Jing Li, Lawrence H Lash, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Well-defined cross-linked antioxidant nanozymes for treatment of ischemic brain injury.

A. Kabanov, E. Batrakova, T. Bronich, 2012, Journal of controlled release : official journal of the Controlled Release Society.

The attenuation of central angiotensin II-dependent pressor response and intra-neuronal signaling by intracarotid injection of nanoformulated copper/zinc superoxide dismutase.

A. Kabanov, E. Batrakova, T. Bronich, 2010, Biomaterials.

Agile delivery of protein therapeutics to CNS.

Alexander V Kabanov, A. Kabanov, D. Manickam, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Macrophages offer a paradigm switch for CNS delivery of therapeutic proteins.

H. Gendelman, A. Kabanov, E. Batrakova, 2014, Nanomedicine.

Antioxidant-based therapies for angiotensin II-associated cardiovascular diseases.

K. Savalia, D. Manickam, M. Zimmerman, 2013, American journal of physiology. Regulatory, integrative and comparative physiology.

Redox-responsive polymer-based gene delivery systems

Yezi You, Jing Li, D. Manickam, 2015 .

Targeting the blood-brain barrier for the delivery of stroke therapies.

D. Manickam, A. D'Souza, R. A. Stetler, 2021, Advanced drug delivery reviews.

Transfection activity of layer-by-layer plasmid DNA/poly(ethylenimine) films deposited on PLGA microparticles.

G. Mao, D. Oupický, D. Manickam, 2009, International journal of pharmaceutics.

Protect the Ischemic Brain Endothelium

D. Stolz, Y. Bae, D. Manickam, 2022 .

Extracellular Vesicle (EV) Mitochondria and EV/HSP27 Mixtures 1 Protect the Ischemic Brain Endothelium 2

D. Stolz, R. Leak, Y. Bae, 2022 .

GC-MS ANALYSIS OF METHANOL EXTRACT OF DECALEPIS HAMILTONII ROOT (WIGHT & ARN)

D. Manickam, L. Periyasamy, Namakkal Dist, 2014 .

PHYTOCHEMICAL ANALYSIS & IN VITRO ANTICANCER ACTIVITY OF METHANOL EXTRACT OF DECALEPIS HAMILTONII ROOT AGAINST HEPATIC CANCER CELL LINES (HepG2)

D. Manickam, D. Preetha, 2016 .

Superoxide Dismutase 1 Nanozyme for Treatment of Eye Inflammation

N. G. Davydova, A. Kabanov, D. Manickam, 2015, Oxidative medicine and cellular longevity.

Nanoformulated copper/zinc superoxide dismutase reduces adipose inflammation in obesity

V. Saraswathi, A. Kabanov, D. Manickam, 2016, Obesity.

Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells

M. Manoharan, D. Manickam, Lauren A. O'Donnell, 2021, The AAPS Journal.

Neuronal Uptake of Nanoformulated Superoxide Dismutase and Attenuation of Angiotensin II-Dependent Hypertension Following Central Administration

K. Savalia, A. Kabanov, D. Manickam, 2014 .

Cross-linked antioxidant nanozymes for improved delivery to CNS.

A. Kabanov, E. Batrakova, T. Bronich, 2012, Nanomedicine : nanotechnology, biology, and medicine.

Engineering Extracellular Vesicles to Modulate Their Innate Mitochondrial Load

D. Stolz, J. Milošević, D. Manickam, 2022, Cellular and Molecular Bioengineering.

Nanoformulated copper/zinc superoxide dismutase attenuates vascular cell activation and aortic inflammation in obesity.

V. Saraswathi, A. Kabanov, D. Manickam, 2016, Biochemical and biophysical research communications.

Brain Infarct Sizes and EV/HSP27 Protect Ischemic Brain

L. McCullough, R. Leak, Y. Bae, 2022 .

Extracellular Vesicles Deliver Mitochondria and HSP27 Protein to Protect the Blood-Brain Barrier

D. Stolz, Y. Bae, D. Manickam, 2021, bioRxiv.

Lipidoid nanoparticles increase ATP uptake into hypoxic brain endothelial cells

J. Conway, D. Manickam, Purva Khare, 2022, bioRxiv.

Characterization of the SIM-A9 cell line as a model of activated microglia in the context of neuropathic pain

D. Manickam, Kandarp M. Dave, Lalah Ali, 2020, PloS one.

Dually responsive multiblock copolymers via reversible addition- fragmentation chain transfer polymerization: Synthesis of temperature- and redox-responsive copolymers of poly(N-isopropylacrylamide) and poly(2-(dimethylamino)ethyl methacrylate)

G. Mao, D. Oupický, Yezi You, 2007 .

Redox -responsive delivery systems for cancer gene therapy

D. Manickam, 2008 .

Stability and structure of Cu(II) and Zn(II) ternary complexes with L-glutamic acid and some diaminocarboxylic acids

D. Manickam, C. Natarajan, M. Nair, 1990, Proceedings / Indian Academy of Sciences.

Lucifer Yellow - A Robust Paracellular Permeability Marker in a Cell Model of the Human Blood-brain Barrier.

Y. Bae, D. Manickam, Linjiang Han, 2019, Journal of visualized experiments : JoVE.

Evaluation of Pharmacokinetics of Bioreducible Gene Delivery Vectors by Real-time PCR

D. Oupický, Qing-hui Zhou, D. Manickam, 2009, Pharmaceutical Research.

Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides

J. Kjems, F. Besenbacher, U. Rahbek, 2008, The journal of gene medicine.

Microvesicles Transfer Mitochondria and Increase Mitochondrial Function in Brain Endothelial Cells

U. Chandran, D. Manickam, A. D'Souza, 2021, bioRxiv.

Microvesicles transfer mitochondria and increase mitochondrial function in brain endothelial cells.

U. Chandran, D. Manickam, A. D'Souza, 2021, Journal of controlled release : official journal of the Controlled Release Society.

SOD1 nanozyme with reduced toxicity and MPS accumulation.

A. Kabanov, Y. Bae, D. Manickam, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Nano-particle delivery of brain derived neurotrophic factor after focal cerebral ischemia reduces tissue injury and enhances behavioral recovery

L. McCullough, W. Banks, A. Kabanov, 2016, Pharmacology Biochemistry and Behavior.

Mitochondria-containing extracellular vesicles (EV) reduce mouse brain infarct sizes and EV/HSP27 protect ischemic brain endothelial cultures.

L. McCullough, D. Stolz, R. Leak, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Delivery of mitochondria via extracellular vesicles - A new horizon in drug delivery.

D. Manickam, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Nanoformulation of Brain‐Derived Neurotrophic Factor with Target Receptor‐Triggered‐Release in the Central Nervous System

W. Banks, A. Kabanov, D. Manickam, 2018, Advanced functional materials.

Antidiabetic effect of methanolic extract of Decalepis hamiltonii root (wight and Arn) in normal and alloxan induced diabetic rats

D. Manickam, L. Periyasamy, 2013 .

Overexpression of Bcl-2 as a proxy redox stimulus to enhance activity of non-viral redox-responsive delivery vectors.

F. Hirata, A. Hirata, D. Oupický, 2008, Biomaterials.

Exosomes and microvesicles (EVs) can be engineered for co-delivery of bio-actives

D. Stolz, Y. Bae, D. Manickam, 2021 .

Multiblock reducible copolypeptides containing histidine-rich and nuclear localization sequences for gene delivery.

D. Oupický, D. Manickam, David Oupický, 2006, Bioconjugate chemistry.

Stimulus-controlled delivery of drugs and genes

D. Oupický, H. Bisht, Qing-hui Zhou, 2005, Expert opinion on drug delivery.

Temperature-controlled properties of DNA complexes with poly(ethylenimine)-graft-poly(N-isopropylacrylamide).

D. Oupický, Yezi You, H. Bisht, 2006, Biomacromolecules.

Neuronal uptake of nanoformulated superoxide dismutase and attenuation of angiotensin II-dependent hypertension after central administration.

K. Savalia, A. Kabanov, D. Manickam, 2014, Free radical biology & medicine.

Lipid nanoparticle-mediated drug delivery to the brain.

D. Manickam, C. Hamadani, Purva Khare, 2023, Advanced drug delivery reviews.

A versatile approach to reducible vinyl polymers via oxidation of telechelic polymers prepared by reversible addition fragmentation chain transfer polymerization.

D. Oupický, Yezi You, Qing-hui Zhou, 2007, Biomacromolecules.

Delivery of mitochondria-containing extracellular vesicles to the BBB for ischemic stroke therapy

D. Manickam, Kandarp M. Dave, Donna B Stolz, 2023, Expert opinion on drug delivery.

Effect of cell membrane thiols and reduction-triggered disassembly on transfection activity of bioreducible polyplexes.

D. Oupický, Jing Li, D. Manickam, 2012, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Mitochondria-containing extracellular vesicles from mouse vs. human brain endothelial cells for ischemic stroke therapy.

D. Manickam, V. Venna, Kandarp M. Dave, 2024, Journal of controlled release : official journal of the Controlled Release Society.

Low pinocytic brain endothelial cells primarily utilize membrane fusion to internalize extracellular vesicles.

D. Manickam, Kandarp M. Dave, Purva Khare, 2024, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.