D. Ginsburg

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Genome-scale CRISPR screening for modifiers of cellular LDL uptake

C. Willer, S. Graham, Brian T. Emmer, 2020, bioRxiv.

Hemophilias and Other Disorders of Hemostasis

J. Shavit, D. Ginsburg, 2014 .

Chapter 73 – Hemophilias and Other Disorders of Hemostasis

J. Shavit, D. Ginsburg, 2013 .

Bone marrow cell trafficking following intravenous administration

R L Wahl, E Recker, R. Wahl, 1999, British journal of haematology.

Origin of cell populations after bone marrow transplantation. Analysis using DNA sequence polymorphisms.

S. Orkin, D. Ginsburg, J. Antin, 1985, The Journal of clinical investigation.

Identification of a point mutation in the adenosine deaminase gene responsible for immunodeficiency.

D. Bonthron, A. Markham, D. Ginsburg, 1985, The Journal of clinical investigation.

Review in translational hematology ADAMTS 13 turns 3

D. Motto, D. Ginsburg, G. Levy, 2005 .

The molecular biology of von Willebrand disease

D. Ginsburg, David Ginsburg, 1999, Haemophilia : the official journal of the World Federation of Hemophilia.

Human von Willebrand factor (vWF): isolation of complementary DNA (cDNA) clones and chromosomal localization.

S. Latt, D. Bonthron, S. Orkin, 1985, Science.

Impaired intracellular transport produced by a subset of type IIA von Willebrand disease mutations.

D. Ginsburg, E. Bowie, S. E. Lyons, 1992, The Journal of biological chemistry.

Moderation of hemophilia A phenotype by the factor V R506Q mutation.

R. Kaufman, D. Ginsburg, K. Michaelides, 1996, Blood.

Familial multiple coagulation factor deficiencies: new biologic insight from rare genetic bleeding disorders

D. Ginsburg, Bin Zhang, B. Zhang, 2004, Journal of thrombosis and haemostasis : JTH.

Dimeric sorting code for concentrative cargo selection by the COPII coat

Xiao-Wei Chen, D. Ginsburg, Huimin Wang, 2018, Proceedings of the National Academy of Sciences.

Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association

Joan E Bailey-Wilson, Cheryl D Cropp, Alexander F Wilson, 2012, Proceedings of the National Academy of Sciences.

Genetic variants in ADAMTS13 as well as smoking are major determinants of plasma ADAMTS13 levels.

Jun Z. Li, C. Kimchi-Sarfaty, Brian T. Emmer, 2017, Blood advances.

A von Willebrand factor fragment containing the D'D3 domains is sufficient to stabilize coagulation factor VIII in mice.

D. Ginsburg, A. Yee, Robert D. Gildersleeve, 2014, Blood.

THROMBOSIS AND HEMOSTASIS A von Willebrand factor fragment containing the D 9 D 3 domains is suf fi cient to stabilize coagulation factor VIII in mice

D. Ginsburg, A. Yee, Robert D. Gildersleeve, 2014 .

Von Willebrand disease.

D. Ginsburg, W. Nichols, J. Robertson, 2008, Pediatric clinics of North America.

Systemic antithrombotic effects of ADAMTS13

A. Chauhan, D. Wagner, D. Motto, 2006, The Journal of experimental medicine.

Homozygosity for Factor V Leiden Leads to Enhanced Thrombosis and Atherosclerosis in Mice

R. Westrick, P. Bodary, Yue-chun Shen, 2005, Circulation.

Tissue factor pathway inhibitor is required for cerebrovascular development in mice.

R. Westrick, D. Ginsburg, H. Weiler, 2020, Blood.

Murine coagulation factor VIII is synthesized in endothelial cells.

D. Ginsburg, R. Khoriaty, A. Cleuren, 2014, Blood.

Polymorphism of adhesion molecule CD31 is not a significant risk factor for graft-versus-host disease.

N. D. Arnold, K. Lunetta, M. Boehnke, 1996, Blood.

Pancreatic SEC23B deficiency is sufficient to explain the perinatal lethality of germline SEC23B deficiency in mice

K. Tomberg, M. Hoenerhoff, D. Ginsburg, 2016, Scientific Reports.

Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse

R. Westrick, K. Tomberg, D. Ginsburg, 2017, bioRxiv.

Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci

Jun Z. Li, R. Westrick, K. Tomberg, 2017, Proceedings of the National Academy of Sciences.

Nathan and Oski's hematology and oncology of infancy and childhood /

A. Look, S. Orkin, D. Ginsburg, 2015 .

The in vivo endothelial cell translatome is highly heterogeneous across vascular beds

W. Aird, S. Ganesh, G. Molema, 2019, Proceedings of the National Academy of Sciences.

Linkage relationship of X-linked juvenile retinoschisis with Xp22.1-p22.3 probes.

P. Sieving, M. R. Young, M. Boehnke, 1990, American journal of human genetics.

Genotype-phenotype correlation in combined deficiency of factor V and factor VIII.

P. Platzer, R. Kaufman, D. Ginsburg, 2008, Blood.

Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice.

A. Chauhan, D. Wagner, D. Motto, 2005, The Journal of clinical investigation.

Modifier genes for disorders of thrombosis and hemostasis

R. Westrick, D. Ginsburg, 2009, Journal of thrombosis and haemostasis : JTH.

Enzymatically Active ADAMTS13 Variants Are Not Inhibited by Anti-ADAMTS13 Autoantibodies

E. Bouhassira, D. Ginsburg, Lingli Dong, 2005, Journal of Biological Chemistry.

Pathogenesis of B cell lymphoma in a patient with AIDS.

S. Orkin, J. Groopman, R. Gallo, 1986, Blood.

Nucleotide sequence of pre-pro-von Willebrand factor cDNA.

D. Bonthron, S. Orkin, D. Ginsburg, 1986, Nucleic acids research.

Murine SEC24D can substitute functionally for SEC24C during embryonic development

K. Tomberg, M. Hoenerhoff, A. Kiseleva, 2021, Scientific Reports.

Enhanced VWF biosynthesis and elevated plasma VWF due to a natural variant in the murine Vwf gene.

J. Long, J. Shavit, D. Ginsburg, 2006, Blood.

The molecular defect in type IIB von Willebrand disease. Identification of four potential missense mutations within the putative GpIb binding domain.

K. Cooney, H. Gralnick, D. Ginsburg, 1991, The Journal of clinical investigation.

Severe von Willebrand disease due to a defect at the level of von Willebrand factor mRNA expression: detection by exonic PCR-restriction fragment length polymorphism analysis.

R. Cody, D. Ginsburg, W. Nichols, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Molecular basis of human von Willebrand disease: analysis of platelet von Willebrand factor mRNA.

D. Ginsburg, R. Montgomery, J. Gill, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Mammalian COPII Coat Component SEC24C Is Required for Embryonic Development in Mice*

Xiao-Wei Chen, D. Ginsburg, K. S. O'Shea, 2014, The Journal of Biological Chemistry.

The small GTPase RAB10 regulates endosomal recycling of the LDL receptor and transferrin receptor in hepatocytes

Brian T. Emmer, D. Ginsburg, B. Emmer, 2022, Journal of lipid research.

Cultured human endothelial cells express platelet-derived growth factor B chain: cDNA cloning and structural analysis

S. Orkin, J. Pober, T. Collins, 1985, Nature.

SEC23B is required for the maintenance of murine professional secretory tissues

Xiao-Wei Chen, D. Ginsburg, Bin Zhang, 2012, Proceedings of the National Academy of Sciences.

pak2a mutations cause cerebral hemorrhage in redhead zebrafish

Julio D Amigo, P. Jagadeeswaran, J. Shavit, 2007, Proceedings of the National Academy of Sciences.

Fatal haemorrhage and incomplete block to embryogenesis in mice lacking coagulation factor V

D. Ginsburg, K. S. O'Shea, J. Cui, 1996, Nature.

Rearrangement of immunoglobulin and T-cell receptor genes in Hodgkin's disease.

D. Ginsburg, E. Bingham, M. Roth, 1988, The American journal of pathology.

Murine SEC24D Can Substitute Functionally for SEC24C in vivo

K. Tomberg, A. Kiseleva, D. Ginsburg, 2018, bioRxiv.

Phenotype of recovering lymphoid cell populations after marrow transplantation

S. Orkin, D. Ginsburg, J. Antin, 1985, The Journal of experimental medicine.

Von Willebrand Factor and ADAMTS13: Too Much or Too Little of a Good Thing?

D. Ginsburg, K. Desch, B. Emmer, 2016, Arteriosclerosis, thrombosis, and vascular biology.

Structure of pre-pro-von Willebrand factor and its expression in heterologous cells

D. Bonthron, S. Orkin, J. Loscalzo, 1986, Nature.

Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol

Brian T. Emmer, D. Ginsburg, Huan Fang, 2022, bioRxiv.

and VIII Deficiency Families ERGIC-53 Gene Structure and Mutation Analysis in 19 Combined Factors V

R. Kaufman, C. Négrier, H. Saito, 2013 .

ERGIC-53 gene structure and mutation analysis in 19 combined factors V and VIII deficiency families.

R. Kaufman, C. Négrier, D. Ginsburg, 1999, Blood.

Exocyst function is regulated by effector phosphorylation.

D. Toomre, Zhaohui Xu, A. Saltiel, 2011, Nature cell biology.

The Function of the Exocyst is Regulated by Effector Phosphorylation

D. Toomre, Zhaohui Xu, Q. Wang, 2011, Nature Cell Biology.

Disruption of the Sec24d Gene Results in Early Embryonic Lethality in the Mouse

D. Ginsburg, Bin Zhang, Elizabeth J. Adams, 2013, PloS one.

Detection of Philadelphia chromosome-positive cells by the polymerase chain reaction following bone marrow transplant for chronic myelogenous leukemia.

D. Ginsburg, E. Bingham, M. Roth, 1989, Blood.

Detection of Philadelphia chromosome-positive cells by the polymerase chain reaction following bone marrow transplant for chronic myelogenous leukemia

D. Ginsburg, E. Bingham, J. Antin, 1989 .

Identification of secreted proteins by comparison of protein abundance in conditioned media and cell lysates

Felipe da Veiga Leprevost, A. Nesvizhskii, D. Ginsburg, 2022, bioRxiv.

Conserved linkage of neurotrophin-3 and von Willebrand factor on mouse Chromosome 6

K. Mohlke, M. Meisler, D. Ginsburg, 2004, Mammalian Genome.

von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene.

K. Cooney, K. Mohlke, D. Ginsburg, 1995, Blood.

Deciphering the mystery of combined factor V and factor VIII deficiency

D. Ginsburg, U. Seligsohn, 2006, Journal of thrombosis and haemostasis : JTH.

Combined factors V and VIII deficiency — the solution

R. Kaufman, C. Kessler, D. Ginsburg, 1998, Haemophilia : the official journal of the World Federation of Hemophilia.

Molecular characterization of a unique von Willebrand disease variant. A novel mutation affecting von Willebrand factor/factor VIII interaction.

D. Ginsburg, W. Nichols, P. Cacheris, 1991, The Journal of biological chemistry.

Neonatal purpura fulminans in association with factor V R506Q mutation.

A. Schmaier, D. Ginsburg, S. Pipe, 1996, The Journal of pediatrics.

Characterization of large structural genetic mosaicism in human autosomes.

William Wheeler, Nan Hu, Peter Kraft, 2015, American journal of human genetics.

leukemia chain reaction following bone marrow transplant for chronic myelogenous Detection of Philadelphia chromosome-positive cells by the polymerase

D. Ginsburg, Rőth, J. Antin, 2011 .

Proteolytic cleavage of recombinant type 2A von Willebrand factor mutants R834W and R834Q: inhibition by doxycycline and by monoclonal antibody VP-1.

R. Nagel, J. Sixma, D. Ginsburg, 1997, Blood.

Comprar Nathan and Oski's Hematology of Infancy and Childhood, 7th Edition | David E. Fisher | 9781416034308 | Saunders

A. Look, S. Orkin, D. Ginsburg, 2009 .

Ki‐1 lymphomas in children

D. Ginsburg, M. Roth, B. Schnitzer, 1988, Cancer.

T-cell receptor gene rearrangement in regressing atypical histiocytosis.

A. Lichter, D. Ginsburg, J. Headington, 1987, Archives of dermatology.

Lethal Perinatal Thrombosis in Mice Resulting From the Interaction of Tissue Factor Pathway Inhibitor Deficiency and Factor V Leiden

R. Westrick, J. Wilkinson, D. Eitzman, 2002, Circulation.

Spontaneous thrombosis in mice carrying the factor V Leiden mutation.

R. Westrick, K. Gallagher, D. Eitzman, 2000, Blood.

Prothrombotic phenotype of protein Z deficiency.

D. Ginsburg, G. Broze, J. Cui, 2000, Proceedings of the National Academy of Sciences of the United States of America.

The structure and function of murine factor V and its inactivation by protein C.

R. Kaufman, D. Ginsburg, J. Cui, 1998, Blood.

A monoclonal antibody to von Willebrand factor (vWF) inhibits factor VIII binding. Localization of its antigenic determinant to a nonadecapeptide at the amino terminus of the mature vWF polypeptide.

D. Ginsburg, W. Bahou, D. Fass, 1989, The Journal of clinical investigation.

Biosynthetic origin and functional significance of murine platelet factor V.

D. Ginsburg, S. Pipe, A. Yang, 2003, Blood.

Localization of the gene for familial primary pulmonary hypertension to chromosome 2q31–32

N. D. Arnold, Daniel L. Koller, T. Foroud, 1997, Nature Genetics.

Early death of factor v leiden hemizygous mice : a fatal absence of wild type FV anticoagulant function

P. Reitsma, R. Westrick, D. Ginsburg, 2011 .

Use of Transgenic Mice in the Study of Thrombosis and Hemostasis

D. Ginsburg, J. Pearson, 1999 .

Vitronectin is not essential for normal mammalian development and fertility.

S. Camper, D. Ginsburg, L. Samuelson, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Rearrangement ofImmunoglobulin and T-Cell Receptor Genes in Hodgkin's Disease

D. Ginsburg, E. Bingham, M. Roth, 2007 .

An unbiased screen identified the Hsp70-BAG3 complex as a regulator of myosin binding protein C3

Sharlene M. Day, J. Gestwicki, D. Ginsburg, 2022, bioRxiv.

A novel modifier gene for plasma von Willebrand factor level maps to distal mouse chromosome 11.

K. Cooney, K. Mohlke, R. Westrick, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The molecular basis of von Willebrand disease

K. Mohlke, D. Ginsburg, W. Nichols, 1999, International journal of clinical & laboratory research.

von Willebrand disease and quantitative variation in von Willebrand factor.

K. Mohlke, D. Ginsburg, David Ginsburg, 1997, The Journal of laboratory and clinical medicine.

von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene [published erratum appears in Blood 1995 Sep 15;86(6):2461]

K. Cooney, K. Mohlke, D. Ginsburg, 1994 .

Molecular genetics of von Willebrand disease.

D. Ginsburg, E. Bowie, 1992, Blood.

Detectable clonal mosaicism from birth to old age and its relationship to cancer

Ingo Ruczinski, Li-e Wang, William L. Lowe, 2012, Nature Genetics.

allelescauses noncell-specific deletion of floxed Germ line activation of the Tie2 and SMMHC

E. Radaelli, J. Haigh, C. Sigmund, 2012 .

Probing ADAMTS13 Substrate Specificity using Phage Display

D. Ginsburg, A. Yee, Robert D. Gildersleeve, 2015, PloS one.

Molecular and cellular biology of von Willebrand factor.

D. Ginsburg, S. E. Lyons, 1994, Trends in cardiovascular medicine.

Propolypeptide of von Willebrand factor circulates in blood and is identical to von Willebrand antigen II.

D. Bonthron, S. Orkin, D. Wagner, 1986, Science.

Identification of novel γ-globin inducers among all potential erythroid druggable targets

J. D. Engel, J. Engel, D. Ginsburg, 2022, Blood advances.

Strain-specific modification of lethality in fucose-deficient mice

B. Gillespie, D. Ginsburg, J. Lowe, 2003, Mammalian Genome.

von Willebrand disease in the RIIIS/J mouse is caused by a defect outside of the von Willebrand factor gene.

K. Cooney, K. Mohlke, D. Ginsburg, 1994, Blood.

Visualization of an N-terminal fragment of von Willebrand factor in complex with factor VIII.

G. Skiniotis, D. Ginsburg, A. Yee, 2015, Blood.

Modiﬁers of von Willebrand factor identiﬁed by natural variation in inbred strains of mice

K. Broman, A. Manichaikul, J. Shavit, 2009 .

Pancreatic SEC 23 B deficiency is sufficient to explain the perinatal lethality of germline SEC 23 B deficiency in mice

Lesley, D. Ginsburg, Bin Zhang, 2016 .

Is heparin administration necessary during induction chemotherapy for patients with acute promyelocytic leukemia?

M. Goldberg, D. Rosenthal, R. Mayer, 1987, Blood.

From the ER to the golgi: insights from the study of combined factors V and VIII deficiency.

D. Ginsburg, W. Nichols, 1999, American journal of human genetics.

LMAN1 and MCFD2 Form a Cargo Receptor Complex and Interact with Coagulation Factor VIII in the Early Secretory Pathway*

R. Kaufman, D. Ginsburg, Bin Zhang, 2005, Journal of Biological Chemistry.

Digital Commons@Becker Digital Commons@Becker Murine Surf4 is essential for early embryonic development Murine Surf4 is essential for early embryonic development

Paul J. Lascuna, D. Ginsburg, R. Khoriaty, 2022 .

Congenital Hemorrhagic Disorders: New Insights into the Pathophysiology and Treatment of Hemophilia.

D. Ginsburg, K. High, J. Lusher, 2000, Hematology. American Society of Hematology. Education Program.

A mutation in LMAN1 (ERGIC-53) causing combined factor V and factor VIII deficiency is prevalent in Jews originating from the island of Djerba in Tunisia

D. Ginsburg, O. Shpilberg, N. Rosenberg, 2004, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex

R. Kaufman, D. Ginsburg, S. Pipe, 2003, Nature Genetics.

Impact, Diagnosis and Treatment of von Willebrand Disease

P. Mannucci, D. Ginsburg, F. Rodeghiero, 2000, Thrombosis and Haemostasis.

Molecular genetic analysis of porcine von Willebrand disease: tight linkage to the von Willebrand factor locus.

D. Ginsburg, D. Fass, E. Bowie, 1988, Blood.

Analysis of the relationship of von Willebrand disease (vWD) and hereditary hemorrhagic telangiectasia and identification of a potential type IIA vWD mutation (IIe865 to Thr).

F. Collins, M. Boehnke, M. Iannuzzi, 1991, American journal of human genetics.

Phage display broadly identifies inhibitor‐reactive regions in von Willebrand factor

F. Meng, J. Shavit, Manhong Dai, 2021, Journal of thrombosis and haemostasis : JTH.

Phage Display Broadly Identifies Inhibitor-reactive Regions in von Willebrand Factor

F. Meng, J. Shavit, Manhong Dai, 2021, bioRxiv.

Rapid Publication Linkage of Combined Factors V and VIII Deficiency to Chromosome 18 q by Homozygosity Mapping

N. D. Arnold, R. Kaufman, D. Ginsburg, 2013 .

Combined factor V and factor VIII deficiency in a Thai patient: a case report of genotype and phenotype characteristics

A. Chuansumrit, D. Ginsburg, S. Pipe, 2005, Haemophilia : the official journal of the World Federation of Hemophilia.

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY Molecular Analysis of the ERGIC-53 Gene in 35 Families With Combined Factor V-Factor VIII Deficiency

S. Antonarakis, C. Rossier, M. Morris, 2015 .

Linkage of combined factors V and VIII deficiency to chromosome 18q by homozygosity mapping.

N. D. Arnold, R. Kaufman, D. Ginsburg, 1997, The Journal of clinical investigation.

Mutations in the ER–Golgi Intermediate Compartment Protein ERGIC-53 Cause Combined Deficiency of Coagulation Factors V and VIII

H. Hauri, R. Kaufman, D. Ginsburg, 1998, Cell.

Modifiers of von Willebrand factor identified by natural variation in inbred strains of mice.

K. Broman, A. Manichaikul, J. Shavit, 2009, Blood.

A Standard Nomenclature for von Willebrand Factor Gene Mutations and Polymorphisms

J. Eikenboom, D. Ginsburg, F. Rodeghiero, 2001, Thrombosis and Haemostasis.

Combined deficiency of factor V and factor VIII is due to mutations in either LMAN1 or MCFD2.

R. Kaufman, D. Ginsburg, Bin Zhang, 2006, Blood.

Functional analysis of a type IIB von Willebrand disease missense mutation: increased binding of large von Willebrand factor multimers to platelets.

K. Cooney, D. Ginsburg, S. E. Lyons, 1992, Proceedings of the National Academy of Sciences of the United States of America.

A Sensitized Genome-Wide ENU Mutagenesis Screen in the Mouse to Identify Genetic Modifiers of Thrombosis.

R. Westrick, D. Ginsburg, A. Peterson, 2004 .

Training the next generation of biomedical investigators in glycosciences.

Richard D Cummings, Ajit Varki, Peter Agre, 2016, The Journal of clinical investigation.

Chemistry and Biology of Serpins

D. Ginsburg, S. Stone, D. Tollefsen, 1997, Advances in Experimental Medicine and Biology.

Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura

T. Foroud, S. Shurin, J. McClintick, 2001, Nature.

platelets implications for the mechanism of von Willebrand factor binding to Comparative analysis of type 2b von Willebrand disease mutations

K. Cooney, D. Ginsburg, 2011 .

Comparative analysis of type 2b von Willebrand disease mutations: implications for the mechanism of von Willebrand factor binding to platelets.

K. Cooney, D. Ginsburg, 1996, Blood.

Mvwf, a Dominant Modifier of Murine von Willebrand Factor, Results from Altered Lineage-Specific Expression of a Glycosyltransferase

K. Mohlke, R. Westrick, D. Ginsburg, 1999, Cell.

Spontaneous 8bp Deletion in Nbeal2 Recapitulates the Gray Platelet Syndrome in Mice

L. Reinholdt, R. Westrick, K. Tomberg, 2016, PloS one.

Spontaneous Irs1 passenger mutation linked to a gene-targeted SerpinB2 allele

K. Mohlke, R. Westrick, D. Ginsburg, 2010, Proceedings of the National Academy of Sciences.

Distant conserved sequences flanking endothelial-specific promoters contain tissue-specific DNase-hypersensitive sites and over-represented motifs.

Aleksey Y Ogurtsov, Francis S Collins, Alexey S Kondrashov, 2006, Human molecular genetics.

SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion

Jiandie D. Lin, R. Schekman, S. Young, 2013, eLife.

Functional Display of Platelet-Binding VWF Fragments on Filamentous Bacteriophage

D. Ginsburg, A. Yee, Fen-lai Tan, 2013, PloS one.

Characterization of Leu777Pro and Ile865Thr type IIA von Willebrand disease mutations.

K. Cooney, D. Ginsburg, P. Bockenstedt, 1994, Blood.

Epitope Mapping of Inhibitory Monoclonal Antibodies to Human von Willebrand Factor by Using Recombinant cDNA Libraries

D. Ginsburg, D. Meyer, V. Siguret, 1994, Thrombosis and Haemostasis.

Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin.

R. Schekman, R. Kaufman, D. Ginsburg, 2011, Blood.

A Critical Analysis of the Role of SNARE Protein SEC22B in Antigen Cross-Presentation.

Y. Niknafs, D. Ginsburg, N. Mathewson, 2017, Cell reports.

Selection on cis-Regulatory Variation at B4galnt2 and Its Influence on von Willebrand Factor in House Mice

D. Tautz, P. Pavlidis, J. Baines, 2008, Molecular biology and evolution.

Prognostic significance of Philadelphia chromosome-positive cells detected by the polymerase chain reaction after allogeneic bone marrow transplant for chronic myelogenous leukemia.

D. Ginsburg, J. Antin, M. Roth, 1992, Blood.

Is heparin administration necessary during induction chemotherapy for patients with acute promyelocytic leukemia

M. Goldberg, R. Mayer, R. Stone, 1987 .

The endothelial-specific regulatory mutation, Mvwf1, is a common mouse founder allele

P. Tucker, R. Westrick, J. Johnsen, 2008, Mammalian Genome.

The von Willebrand factor gene and genetics of von Willebrand's disease.

D. Ginsburg, 1991, Mayo Clinic proceedings.

SNARE protein SEC22B regulates early embryonic development

M. Hoenerhoff, D. Ginsburg, K. Oravecz-Wilson, 2019, Scientific Reports.

marrow transplant for chronic myelogenous leukemia detected by the polymerase chain reaction after allogeneic bone Prognostic significance of Philadelphia chromosome-positive cells

D. Ginsburg, Rőth, J. Antin, 2011 .

A sensitized mutagenesis screen in Factor V Leiden mice identifies novel thrombosis suppressor loci

Jun Z. Li, R. Westrick, K. Tomberg, 2017, bioRxiv.

lymphohematopoietic engraftment eradication of the PNH clone and documentation of complete Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria

S. Orkin, B. Smith, D. Ginsburg, 2011 .

Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria: eradication of the PNH clone and documentation of complete lymphohematopoietic engraftment

S. Orkin, B. Smith, D. Ginsburg, 1985 .

Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria: eradication of the PNH clone and documentation of complete lymphohematopoietic engraftment.

S. Orkin, D. Ginsburg, D. Nathan, 1985, Blood.

Cargo selection in endoplasmic reticulum–to–Golgi transport and relevant diseases

D. Ginsburg, Vi T. Tang, 2023, The Journal of clinical investigation.

The COPII cargo adapter SEC24C is essential for neuronal homeostasis

Shondra M. Pruett-Miller, Stanislav S Zakharenko, M. Kundu, 2018, The Journal of clinical investigation.

Getting at the Variable Expressivity of Von Willebrand Disease

D. Ginsburg, G. Levy, 2001, Thrombosis and Haemostasis.

The COPII pathway and hematologic disease.

D. Ginsburg, R. Khoriaty, Matthew P. Vasievich, 2010, Blood.

Sequence variation at multiple loci influences red cell hemoglobin concentration.

Magalie S Leduc, G. Churchill, A. Lambert, 2010, Blood.

Absence of a Red Blood Cell Phenotype in Mice with Hematopoietic Deficiency of SEC23B

D. Ginsburg, Bin Zhang, I. Maillard, 2014, Molecular and Cellular Biology.

ADAMTS13 turns 3.

D. Motto, D. Ginsburg, G. Levy, 2005, Blood.

patients with acute promyelocytic leukemia? Is heparin administration necessary during induction chemotherapy for

M. Goldberg, D. Rosenthal, R. Mayer, 2011 .

ADAMTS13 gene mutation in congenital thrombotic thrombocytopenic purpura with previously reported normal VWF cleaving protease activity.

D. Ginsburg, S. Savaşan, H. Tsai, 2003, Blood.

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.

Andrew D. Johnson, Audrey Y. Chu, M. Fornage, 2017, American journal of human genetics.

Genetic regulation of plasma von Willebrand factor levels: quantitative trait loci analysis in a mouse model

K. Broman, J. Shavit, D. Ginsburg, 2007, Journal of thrombosis and haemostasis : JTH.

A common frameshift mutation in von Willebrand factor does not alter mRNA stability but interferes with normal propeptide processing

K. Mohlke, A. Rehemtulla, D. Ginsburg, 1996, British journal of haematology.

USE OF POLYMERASE CHAIN REACTION‐DETECTED SEQUENCE POLYMORPHISMS TO DOCUMENT ENGRAFTMENT FOLLOWING ALLOGENEIC BONE MARROW TRANSPLANTATION

D. Ginsburg, E. Bingham, M. Roth, 1990, Transplantation.

Murine Surf4 is essential for early embryonic development

Brian T. Emmer, Paul J. Lascuna, D. Ginsburg, 2019, bioRxiv.

Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo

A. Gingras, A. Nesvizhskii, D. Klionsky, 2018, Proceedings of the National Academy of Sciences.

The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9

A. Gingras, G. Hesketh, Xiao-Wei Chen, 2018, bioRxiv.

SEC23B is required for pancreatic acinar cell function in adult mice

M. Hoenerhoff, D. Ginsburg, M. Sans, 2017, Molecular biology of the cell.

Cargo Selectivity of the ERGIC‐53/MCFD2 Transport Receptor Complex

H. Hauri, R. Kaufman, D. Ginsburg, 2006, Traffic.

Deficiency of plasminogen activator inhibitor‐2 results in accelerated tumor growth

R. Westrick, D. Ginsburg, M. Roh, 2020, Journal of thrombosis and haemostasis : JTH.

Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels

Andrew D. Johnson, C. Ward‐Caviness, M. Fornage, 2019, Circulation.

Getting Secretory Granules Ready for Prime Time

D. Ginsburg, Bin Zhang, 2003, Cell.

Rescue of Fatal Neonatal Hemorrhage in Factor V Deficient Mice by Low Level Transgene Expression

D. Ginsburg, J. Cui, Stephen J. Gruber, 2000, Thrombosis and Haemostasis.

Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse

R. Westrick, K. Tomberg, D. Ginsburg, 2017, bioRxiv.

The Function of the COPII Gene Paralogs SEC23A and SEC23B Are Interchangeable In Vivo

A. Gingras, A. Nesvizhskii, D. Klionsky, 2017, bioRxiv.

Mannose-dependent Endoplasmic Reticulum (ER)-Golgi Intermediate Compartment-53-mediated ER to Golgi Trafficking of Coagulation Factors V and VIII*

H. Hauri, R. Kaufman, D. Ginsburg, 1999, The Journal of Biological Chemistry.

Whole exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease.

D. Goldstein, Jun Z. Li, P. Reitsma, 2020, Blood.

The factor V Leiden mutation results in the in vivo loss of a critical FV anticoagulant function

R. Westrick, D. Eitzman, D. Ginsburg, 2003 .

A Database of Polymorphisms in the von Willebrand Factor Gene and Pseudogene

D. Ginsburg, J. Sadler, 1993, Thrombosis and Haemostasis.

Donor-recipient mismatch for common gene deletion polymorphisms in graft-versus-host disease

S. Mccarroll, D. Altshuler, L. Zhao, 2009, Nature Genetics.

IgV somatic mutation of human anti–SARS-CoV-2 monoclonal antibodies governs neutralization and breadth of reactivity

Aaron M. Rosenfeld, E. L. Prak, J. Platt, 2021, JCI insight.

A diagnosis of discernment: Identifying a novel ATRX mutation in myelodysplastic syndrome with acquired α-thalassemia.

Radhika Takiar, D. Ginsburg, S. Choi, 2019, Cancer genetics.

The combined roles of ADAMTS13 and VWF in murine models of TTP, endotoxemia, and thrombosis.

A. Chauhan, D. Wagner, D. Motto, 2008, Blood.

Genetic variants in PLG, LPA, and SIGLEC 14 as well as smoking contribute to plasma plasminogen levels.

Jun Z. Li, Y. Guan, Hong-Dong Li, 2014, Blood.

Genome-scale CRISPR screening for modifiers of cellular LDL uptake.

C. Willer, S. Graham, Paul J. Lascuna, 2021, PLoS genetics.

Altered phenotype in LMAN1-deficient mice with low levels of residual LMAN1 expression.

D. Ginsburg, Bin Zhang, R. Khoriaty, 2020, Blood advances.

LMAN1 is a molecular chaperone for the secretion of coagulation factor VIII 1

H. Hauri, D. Ginsburg, S. Pipe, 2003, Journal of thrombosis and haemostasis : JTH.

Analysis of MCFD2- and LMAN1-deficient mice demonstrates distinct functions in vivo.

D. Ginsburg, Bin Zhang, Wei-Jie Wei, 2018, Blood advances.

either LMAN1 or MCFD2 Combined deficiency of factor V and factor VIII is due to mutations in

R. Kaufman, D. Ginsburg, F. Peyvandi, 2013 .

Von Willebrand Disease: A Database of Point Mutations, Insertions, and Deletions

D. Ginsburg, E. Sadler, 1993, Thrombosis and Haemostasis.

Genome‐wide studies of von Willebrand factor propeptide identify loci contributing to variation in propeptide levels and von Willebrand factor clearance

L. Brody, J. Mills, D. Ginsburg, 2016, Journal of thrombosis and haemostasis : JTH.

Genom e-wide stud ies of von Willebrand Factor Propeptide I dentify Loci Contributing to Variation in Propeptide Levels and von Willebrand Factor

L. Brody, J. Mills, D. Ginsburg, 2016 .

Fine Mapping of Monoclonal Antibody Epitopes on Human von Willebrand Factor Using a Recombinant Peptide Library

P. Foster, D. Ginsburg, R. Montgomery, 1992, Thrombosis and Haemostasis.

Targeted Gene Sequencing Identifies Variants in the Protein C and Endothelial Protein C Receptor Genes in Patients With Unprovoked Venous Thromboembolism

D. Dwivedi, P. Liaw, D. Ginsburg, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands

A. Varki, J. Marth, D. Ginsburg, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Sizing of the human T cell receptor alpha locus and detection of a large deletion in the Molt-4 cell line.

F. Collins, D. Ginsburg, M. Roth, 1988, Blood.

Antidote-controlled platelet inhibition targeting von Willebrand factor with aptamers.

B. Sullenger, R. Becker, D. Ginsburg, 2007, Oligonucleotides.

High throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13

K. Tomberg, D. Ginsburg, A. Yee, 2018, Scientific Reports.

Comparative mapping of distal murine chromosome 11 and human 17q21.3 in a region containing a modifying locus for murine plasma von Willebrand factor level.

K. Mohlke, R. Westrick, D. Ginsburg, 1998, Genomics.

Identifying novel genetic determinants of hemostatic balance

D. Ginsburg, D Ginsburg, David Ginsburg, 2005, Journal of thrombosis and haemostasis : JTH.

ADAMTS13 Binds VWF Via its C-Terminal CUB2 Domain.

D. Motto, D. Ginsburg, Weirui Zhang, 2004 .

The thrombomodulin analog Solulin promotes reperfusion and reduces infarct volume in a thrombotic stroke model

E. Su, D. Lawrence, D. Ginsburg, 2011, Journal of thrombosis and haemostasis : JTH.

SacI RFLP in the human von Willebrand factor gene.

F. Collins, M. Iannuzzi, D. Ginsburg, 1987, Nucleic acids research.

RsaI RFLP in the human von Willebrand factor gene.

F. Collins, M. Iannuzzi, D. Ginsburg, 1987, Nucleic acids research.

Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13

F. Kondrashov, F. Meng, K. Tomberg, 2015, Proceedings of the National Academy of Sciences.

The Metalloprotease ADAMTS13 Is a Natural Anti-Thrombotic.

A. Chauhan, D. Wagner, D. Motto, 2005 .

Additional Environmental and/or Genetic Factors Are Required to Trigger TTP in ADAMTS13-Deficient Mice.

D. Motto, D. Ginsburg, J. Homeister, 2004 .

Analysis of Informed Consent Document Utilization in a Minimal-Risk Genetic Study

D. Ginsburg, Scott Y. H. Kim, N. Laventhal, 2011, Annals of Internal Medicine.

Running title : SEC 23 B deletion in acinar cells

M. Hoenerhoff, D. Ginsburg, M. Sans, 2017 .

Genome‐wide linkage analysis and whole‐exome sequencing identifies an ITGA2B mutation in a family with thrombocytopenia

Jun Z. Li, C. Ross, J. Shavit, 2019, British journal of haematology.

Identification of LMAN1 and SURF4 dependent secretory cargoes

Felipe da Veiga Leprevost, A. Nesvizhskii, D. Ginsburg, 2023, bioRxiv.

Coagulation Factor VIII Is Synthesized In Endothelial Cells

D. Ginsburg, R. Khoriaty, A. Cleuren, 2013 .

Molecular Genetics of von Willebrand Disease

D. Ginsburg, 1999, Thrombosis and Haemostasis.

High throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13

K. Tomberg, D. Ginsburg, A. Yee, 2018, Scientific Reports.

Exome Sequencing Studies Identify Mutations in STAB2 As a Genetic Risk for Venous Thromboembolic Disease

D. Goldstein, Jun Z. Li, P. Reitsma, 2017 .

Exome Sequencing in Venous Thromboembolic Disease Identifies Excess Mutation Burden in PROS1, PROC, SERPINC1 and STAB2

D. Goldstein, P. Reitsma, D. Trégouët, 2016 .

Genetics and Genomics to the Clinic: A Long Road ahead

D. Ginsburg, 2011, Cell.

The COPII pathway and hematologic disease.

D. Ginsburg, R. Khoriaty, Matthew P. Vasievich, 2010, Blood.

The Function of the Exocyst is Regulated by Effector Phosphorylation

D. Toomre, Zhaohui Xu, A. Saltiel, 2011, Nature Cell Biology.

The Function of the Exocyst Is Regulated by Effector Phosphorylation Hhs Public Access Introduction

D. Toomre, Zhaohui Xu, A. Saltiel, 2022 .