B. Peterson

发表

Synthetic cell surface receptors for delivery of therapeutics and probes.

D. Hymel, B. Peterson, 2012, Advanced drug delivery reviews.

A synthetic mimic of human Fc receptors: defined chemical modification of cell surfaces enables efficient endocytic uptake of human immunoglobulin-G.

Scott E. Martin, B. Peterson, S. Boonyarattanakalin, 2006, Journal of the American Chemical Society.

Structural Insights into Mechanisms of Catalysis and Inhibition in Norwalk Virus Polymerase*

Blake R. Peterson, Francisco Parra, K. Ng, 2008, Journal of Biological Chemistry.

Anticancer/Antiviral Agent Akt Inhibitor-IV Massively Accumulates in Mitochondria and Potently Disrupts Cellular Bioenergetics

B. Peterson, J. M. Meinig, 2014, ACS chemical biology.

Rapid detection of protein tyrosine kinase activity in recombinant yeast expressing a universal substrate.

B. Peterson, D. D. Clark, 2002, Journal of proteome research.

Sensitivity of Mitochondrial Transcription and Resistance of RNA Polymerase II Dependent Nuclear Transcription to Antiviral Ribonucleosides

J. Arnold, C. Cameron, A. Gnatt, 2012, PLoS pathogens.

Augmenting vitamin D to combat genetic disease.

B. Peterson, 2002, Chemistry & biology.

Carnosine Protects Macrophages against the Toxicity of Aβ1-42 Oligomers by Decreasing Oxidative Stress

S. Lunte, F. Drago, F. Caraci, 2021, Biomedicines.

Antibody–Drug Conjugate that Exhibits Synergistic Cytotoxicity with an Endosome–Disruptive Peptide

D. Hymel, B. Peterson, Zhe Gao, 2019, ACS omega.

Control of gene expression with small molecules: biotin-mediated acylation of targeted lysine residues in recombinant yeast.

B. Peterson, Sonalee Athavankar, 2003, Chemistry & biology.

Decreased APOE-containing HDL subfractions and cholesterol efflux capacity of serum in mice lacking Pcsk9

A. Prat, R. Korstanje, B. Peterson, 2013, Lipids in Health and Disease.

Interaction of 3β-amino-5-cholestene with phospholipids in binary and ternary bilayer membranes.

B. Peterson, J. Slotte, Oskar Engberg, 2012, Langmuir : the ACS journal of surfaces and colloids.

Figure 16, Validated hit and SAR strategy

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Human Neutrophil Peptides Mediate Endothelial-Monocyte Interaction, Foam Cell Formation, and Platelet Activation

Arthur S Slutsky, W. Kuebler, Haibo Zhang, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Fluorescent detection of peroxynitrite during antibody-dependent cellular phagocytosis.

Erick J Carlson, B. Peterson, Digamber Rane, 2020, Methods in enzymology.

Targeting Fluorescent Sensors to Endoplasmic Reticulum Membranes Enables Detection of Peroxynitrite During Cellular Phagocytosis.

B. Peterson, Digamber Rane, Kelsey E. Knewtson, 2018, ACS chemical biology.

Efficient delivery of streptavidin to mammalian cells: clathrin-mediated endocytosis regulated by a synthetic ligand.

B. Peterson, S. L. Hussey, 2002, Journal of the American Chemical Society.

A colorimetric enzyme‐linked on‐bead assay for identification of synthetic substrates of protein tyrosine kinases

Scott E. Martin, B. Peterson, Scott E. Martin, 2002, Journal of Peptide Science.

Synthesis of fluorinated benzophenones, xanthones, acridones, and thioxanthones by iterative nucleophilic aromatic substitution.

B. Peterson, Liqiang Fu, Zachary R. Woydziak, 2012, The Journal of organic chemistry.

The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

J. Peters, K. S. Prabhu, J. Heuvel, 2007 .

Facile synthesis of cids: biotinylated estrone oximes efficiently heterodimerize estrogen receptor and streptavidin proteins in yeast three hybrid systems.

B. Peterson, S. Muddana, Smita S. Muddana, 2004, Organic letters.

Synthetic mimics of mammalian cell surface receptors: prosthetic molecules that augment living cells.

B. Peterson, 2005, Organic & biomolecular chemistry.

Quantification of Engagement of Microtubules by Small Molecules in Living Cells by Flow Cytometry

B. Peterson, Digamber Rane, Angelo E Andres, 2022, ACS bio & med chem Au.

Synthesis of a Universal 5‐Nitroindole Ribonucleotide and Incorporation into RNA by a Viral RNA‐Dependent RNA Polymerase

C. Cameron, B. Peterson, D. Harki, 2007, Chembiochem : a European journal of chemical biology.

Endocytic delivery of vancomycin mediated by a synthetic cell surface receptor: rescue of bacterially infected Mammalian cells and tissue targeting in vivo.

A. August, B. Peterson, S. Boonyarattanakalin, 2007, Journal of the American Chemical Society.

Synthetic mimics of small Mammalian cell surface receptors.

Scott E. Martin, B. Peterson, S. Boonyarattanakalin, 2004, Journal of the American Chemical Society.

National Cholesterol Awareness Month Article Human Neutrophil Peptides Mediate Endothelial-Monocyte Interaction, Foam Cell Formation, and Platelet Activation

W. Kuebler, Haibo Zhang, E. Charbonney, 2017 .

Antibacterial and hemolytic activities of pyridinium polymers as a function of the spatial relationship between the positive charge and the pendant alkyl tail.

Ayusman Sen, B. Peterson, V. Sambhy, 2008, Angewandte Chemie.

Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses.

C. Cameron, E. Smidansky, B. Peterson, 2010, Journal of medicinal chemistry.

One-pot synthesis of nucleoside 5'-triphosphates from nucleoside 5'-H-phosphonates.

C. Cameron, E. Smidansky, B. Peterson, 2008, Organic letters.

Faculty Opinions recommendation of A strain-promoted [3 + 2] azide-alkyne cycloaddition for covalent modification of biomolecules in living systems.

B. Peterson, 2004 .

Synthesis of a beta-estradiol-biotin chimera that potently heterodimerizes estrogen receptor and streptavidin proteins in a yeast three-hybrid system.

B. Peterson, S. L. Hussey, S. Muddana, 2003, Journal of the American Chemical Society.

The Pennsylvania Green Fluorophore: a hybrid of Oregon Green and Tokyo Green for the construction of hydrophobic and pH-insensitive molecular probes.

B. Peterson, S. Boonyarattanakalin, L. Mottram, 2006, Organic letters.

An amphotericin B-fluorescein conjugate as a powerful probe for biochemical studies of the membrane.

Scott E. Martin, M. Sohrmann, E. Carreira, 2004, Angewandte Chemie.

Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2.

A. Iyer, A. August, B. Peterson, 2011, The international journal of biochemistry & cell biology.

Hydrophobic resorufamine derivatives: potent and selective red fluorescent probes of the endoplasmic reticulum of mammalian cells.

B. Peterson, Digamber Rane, Zhe Gao, 2016, Dyes and pigments : an international journal.

Visible photorelease of liquid biopsy markers following microfluidic affinity-enrichment.

S. Soper, M. Witek, R. Givens, 2020, Chemical communications.

Selective disruption of early/recycling endosomes: release of disulfide-linked cargo mediated by a N-alkyl-3beta-cholesterylamine-capped peptide.

B. Peterson, Qi Sun, Sutang Cai, 2008, Journal of the American Chemical Society.

Synthesis and antiviral activity of 5-substituted cytidine analogues: identification of a potent inhibitor of viral RNA-dependent RNA polymerases.

C. Cameron, B. Peterson, D. Harki, 2006, Journal of medicinal chemistry.

Synthesis and antiviral evaluation of a mutagenic and non-hydrogen bonding ribonucleoside analogue: 1-beta-D-Ribofuranosyl-3-nitropyrrole.

C. Cameron, Saikat Ghosh, B. Peterson, 2002, Biochemistry.

Development of a cell-based, high-throughput screening assay for cholesterol efflux using a fluorescent mimic of cholesterol.

P. Kris-Etherton, B. Peterson, Jun Zhang, 2011, Assay and drug development technologies.

A fluorescence-based high performance liquid chromatographic method for the characterization of palmitoyl acyl transferase activity.

B. Peterson, Charles D Smith, S. Creaser, 2002, Analytical biochemistry.

Molecule-specific imaging with mass spectrometry and a buckminsterfullerene probe: application to characterizing solid-phase synthesized combinatorial libraries.

Scott E. Martin, B. Peterson, N. Winograd, 2004, Journal of the American Chemical Society.

Dissolution of Cholesterol in Water by a Synthetic Receptor

F. Diederich, B. Peterson, 1994 .

A synthetic membrane-anchored antigen efficiently promotes uptake of antifluorescein antibodies and associated protein a by mammalian cells.

B. Peterson, S. L. Hussey, E. He, 2001, Journal of the American Chemical Society.

Synthesis of a Fluorescent Analogue of Paclitaxel That Selectively Binds Microtubules and Sensitively Detects Efflux by P-Glycoprotein.

B. Peterson, Zhe Gao, Molly M. Lee, 2017, Angewandte Chemie.

Multifunctional silane polymers for persistent surface derivatization and their antimicrobial properties.

Ayusman Sen, B. Peterson, V. Sambhy, 2008, Langmuir : the ACS journal of surfaces and colloids.

Bilirubin Conformational Analysis and Circular Dichroism

B. Peterson, D. Lightner, R. V. Person, 1994 .

Macrotricyclic Steroid Receptors by Pd°‐Catalyzed Cross‐Coupling Reactions: Dissolution of cholesterol in aqueous solution and investigations of the principles governing selective molecular recognition of steroidal substrates

F. Diederich, B. Jaun, V. Gramlich, 1998 .

Synthesis and biological evaluation of analogues of AKT (protein kinase B) inhibitor-IV.

B. Peterson, B. He, Qi Sun, 2011, Journal of medicinal chemistry.

Fluorescent mimics of cholesterol that rapidly bind surfaces of living mammalian cells.

D. Hymel, B. Peterson, R. Henkhaus, 2015, Chemical communications.

Silver bromide nanoparticle/polymer composites: dual action tunable antimicrobial materials.

Ayusman Sen, B. Peterson, Ayusman Sen, 2006, Journal of the American Chemical Society.

Steroid complexation by cyclophane receptors in aqueous solution: Substrate selectivity, enthalpic driving force for cavity inclusion, and enthalpy-entropy compensation

F. Diederich, B. Peterson, D. Carcanague, 1995 .

11β-Alkyl-Δ9-19-Nortestosterone Derivatives: High-Affinity Ligands and Potent Partial Agonists of the Androgen Receptor

B. Peterson, S. Muddana, Megan M. MacBride, 2004 .

Quantification of Small Molecule–Protein Interactions using FRET between Tryptophan and the Pacific Blue Fluorophore

B. Peterson, Molly M. Lee, Blake R. Peterson, 2016, ACS omega.

Malleilactone Is a Burkholderia pseudomallei Virulence Factor Regulated by Antibiotics and Quorum Sensing

M. Rivera, Benjamin Neuenswander, J. Douglas, 2018, Journal of bacteriology.

Synthesis of Fluorophores that Target Small Molecules to the Endoplasmic Reticulum of Living Mammalian Cells.

B. Peterson, Liqiang Fu, J. M. Meinig, 2015, Angewandte Chemie.

Sensitive and rapid analysis of protein palmitoylation with a synthetic cell-permeable mimic of SRC oncoproteins.

B. Peterson, S. Creaser, 2002, Journal of the American Chemical Society.

Small Molecule Inhibitors of the BfrB–Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity

M. Rivera, B. Peterson, K. Battaile, 2019, Journal of the American Chemical Society.

Synthesis of a high-affinity fluorescent PPARgamma ligand for high-throughput fluorescence polarization assays.

Jerry T. Thompson, B. Peterson, M. DeGrazia, 2003, Bioorganic & medicinal chemistry.

Lethal Mutagenesis of Picornaviruses with N-6-Modified Purine Nucleoside Analogues

Blake R. Peterson, J. Martin Bollinger, David Loakes, 2008, Antimicrobial Agents and Chemotherapy.

Calcium Flux in Neuroblastoma Cells Is a Coupling Mechanism between Non-Genomic and Genomic Modes of Estrogens

D. Pfaff, N. Vasudevan, B. Peterson, 2005, Neuroendocrinology.

Analysis of Protein Tyrosine Kinase Inhibitors in Recombinant Yeast Lacking the ERG6 Gene

B. Peterson, Daniel D. Clark, 2003, Chembiochem : a European journal of chemical biology.

Small-molecule triggers of tadpole metamorphosis.

B. Peterson, 2006, ACS chemical biology.

Lethal Mutagenesis of Picornaviruses with N-6-Modiﬁed Purine Nucleoside Analogues (cid:1) †

C. Cameron, J. Bollinger, E. Smidansky, 2008 .

A synthetic rhamnose glycopolymer cell surface receptor for endogenous antibody recruitment.

S. van Calenbergh, L. Albertazzi, B. D. De Geest, 2019, Biomacromolecules.

Identification of a small molecule yeast TORC 1 inhibitor with a flow cytometry-based multiplex screen

Terry D. Foutz, Jennifer E. Golden, Susan M. Young, 2012 .

Endocytosis: Receptor-Mediated

B. Peterson, 2008 .

The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).

J. V. Vanden Heuvel, J. Peters, K. S. Prabhu, 2007, Free radical biology & medicine.

Chemico-genetic identification of drebrin as a regulator of calcium responses.

T. Shirao, A. Iyer, A. August, 2010, The international journal of biochemistry & cell biology.

Targeting of histone acetyltransferase p300 by cyclopentenone prostaglandin Δ(12)-PGJ(2) through covalent binding to Cys(1438).

K. S. Prabhu, G. Lushington, V. Narayan, 2012, Chemical research in toxicology.

Synthesis of an artificial cell surface receptor that enables oligohistidine affinity tags to function as metal-dependent cell-penetrating peptides.

B. Peterson, S. Boonyarattanakalin, Qi Sun, 2006, Journal of the American Chemical Society.

Riding the Coronacoaster: Learning, Teaching, and Living at a Health Sciences Campus during the COVID-19 Pandemic

B. Peterson, Fiza Khan, Chandi Katoch, 2020, Anthropologica.

Detection of Protein–Protein Interactions by Proximity-Driven SNAr Reactions of Lysine-Linked Fluorophores

D. Hymel, B. Peterson, Zachary R. Woydziak, 2014, Journal of the American Chemical Society.

Fluorescent Detection of Peroxynitrite Produced by Myeloid-Derived Suppressor Cells in Cancer and Inhibition by Dasatinib.

Erick J Carlson, B. Peterson, Gabriella Lapurga, 2023, ACS pharmacology & translational science.

Fluorescent Cellular Sensors of Steroid Receptor Ligands

B. Peterson, Smita S. Muddana, 2003, Chembiochem : a European journal of chemical biology.

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.

Terry D. Foutz, Tuanli Yao, Jennifer E. Golden, 2012, ACS chemical biology.

A concise synthesis of the Pennsylvania Green fluorophore and labeling of intracellular targets with O6-benzylguanine derivatives.

M. Schwab, B. Peterson, F. Beaufils, 2007, Organic letters.

Cavity depth and width effects on cyclophane-steroid recognition: molecular complexation of cholesterol and progesterone in aqueous solution.

F. Diederich, B. Peterson, T. Mordasini-Denti, 1995, Chemistry & biology.

Hydrophobic analogues of rhodamine B and rhodamine 101: potent fluorescent probes of mitochondria in living C. elegans

B. Peterson, Brian D. Ackley, Safiyyah Forbes, 2012, Beilstein journal of organic chemistry.

The C. elegans CHP1 homolog, pbo-1, functions in innate immunity by regulating the pH of the intestinal lumen

B. Peterson, Josephine R. Chandler, Brian D. Ackley, 2018, bioRxiv.

Novel acid-activated fluorophores reveal a dynamic wave of protons in the intestine of Caenorhabditis elegans.

M. Branden, Zhenguo Zhou, B. Peterson, 2013, ACS chemical biology.

Photoluminescent Properties and Mechanism of Novel Cyanine-Borondifluoride Curcuminoid Hybrids as Red to Near-Infrared and Endoplasmic Reticulum-Targeting Dyes.

F. Feng, B. Peterson, Qi Sun, 2023, Chemistry.

BTK inhibition potentiates anti-PD-L1 treatment in murine melanoma: potential role for MDSC modulation in immunotherapy

Erick J Carlson, P. Trikha, B. Peterson, 2023, Cancer Immunology, Immunotherapy.

Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma

Ryan D. Morin, R. Morin, K. Young, 2023, Leukemia.

Figure 6, Schematic of screen strategy

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

A critical arginine residue mediates cooperativity in the contact interface between transcription factors NFAT and AP-1.

G. Verdine, B. Peterson, L. Sun, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Antibacterial and hemolytic activities of pyridinium polymers as a function of the spatial relationship between the positive charge and the pendant alkyl tail.

Ayusman Sen, B. Peterson, V. Sambhy, 2008, Angewandte Chemie.

Lethal Mutagenesis of Poliovirus Mediated by a Mutagenic Pyrimidine Analogue

Blake R. Peterson, David Loakes, C. Cameron, 2007, Journal of Virology.

Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2.

A. August, B. Peterson, Mankit Law, 2011, The international journal of biochemistry & cell biology.

Dual role of the nuclear factor of activated T cells insert region in DNA recognition and cooperative contacts to activator protein 1.

G L Verdine, G. Verdine, B. Peterson, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Fluorescence‐Based Cloning of a Protein Tyrosine Kinase with a Yeast Tribrid System

B. Peterson, Daniel D. Clark, 2005, Chembiochem : a European journal of chemical biology.

Figure 10, TORC1 bypass cell growth analysis on the probe ML231 and SID 96099781

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Practical synthesis of 3beta-amino-5-cholestene and related 3beta-halides involving i-steroid and retro-i-steroid rearrangements.

B. Peterson, Qi Sun, Sutang Cai, 2009, Organic letters.