D. Chung

发表

M. McDowell, C. Jonsson, Harish N. Ramanathan, 2007 .

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes

Tudor I. Oprea, Jennifer E. Golden, Joshua A. Bittker, 2015, Cell.

(S)-N-(2,5-Dimethylphenyl)-1-(quinoline-8-ylsulfonyl)pyrrolidine-2-carboxamide as a small molecule inhibitor probe for the study of respiratory syncytial virus infection.

Jennifer E. Golden, Nichole A. Tower, C. Jonsson, 2012, Journal of medicinal chemistry.

Evaluation of anti‐Zika virus activities of broad‐spectrum antivirals and NIH clinical collection compounds using a cell‐based, high‐throughput screen assay

Jennifer E. Golden, D. Chung, Y. Chu, 2017, Antiviral research.

Development of (E)-2-((1,4-Dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-Amidinophenylbenzamides as Potent Inhibitors of Venezuelan Equine Encephalitis Virus

Jennifer E. Golden, Nichole A. Tower, C. Jonsson, 2014, Journal of medicinal chemistry.

Discovery of a Novel Compound with Anti-Venezuelan Equine Encephalitis Virus Activity That Targets the Nonstructural Protein 2

Jennifer E. Golden, Nichole A. Tower, Claire Marie Filone, 2014, PLoS pathogens.

Table 1, ML336 Data Summary

Tuanli Yao, Chad E. Schroeder, Jennifer E. Golden, 2013 .

Rate of hepatitis C viral clearance by human livers in human patients: Liver transplantation modeling primary infection and implications for studying entry inhibition

M. Brier, C. McClain, Sreelatha T. Reddy, 2017, PloS one.

A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus

Jennifer E. Golden, C. Jonsson, D. Chung, 2013, Virology Journal.

Phenotypic Differences in Virulence and Immune Response in Closely Related Clinical Isolates of Influenza A 2009 H1N1 Pandemic Viruses in Mice

T. Wiemken, J. Ramirez, C. Jonsson, 2013, PloS one.

Phylogenetic and Variant Analysis of 1,040 SARS-CoV-2 Genomes

J. Chariker, E. Rouchka, D. Chung, 2020 .

Synthesis of 1-beta-D-ribofuranosyl-3-ethynyl-[1,2,4]triazole and its in vitro and in vivo efficacy against Hantavirus.

Qianjun Li, C. Jonsson, Harish N. Ramanathan, 2008, Antiviral research.

Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State

Jennifer E. Golden, R. Davey, X. Zhang, 2016, Antimicrobial Agents and Chemotherapy.

Synthesis and anti-Hantaan virus activity of N(1)-3-fluorophenyl-inosine.

C. Jonsson, D. Chung, W. Parker, 2009, Antiviral research.

Activity of Ribavirin against Hantaan Virus Correlates with Production of Ribavirin-5′-Triphosphate, Not with Inhibition of IMP Dehydrogenase

C. Jonsson, D. Chung, Y. Chu, 2006, Antimicrobial Agents and Chemotherapy.

A Novel Compound, ML336, Inhibits VEEV Replication by Interfering with Viral RNA Synthesis

Jennifer E. Golden, C. Jonsson, D. Chung, 2018, bioRxiv.

Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19

R. Davey, V. Gandhi, D. Chung, 2022, bioRxiv.

Potent Antiviral Activity against HSV-1 and SARS-CoV-2 by Antimicrobial Peptoids

A. Barron, Nathen E. Bopp, D. Chung, 2020, Pharmaceuticals.

Efficacy of a ML336 derivative against Venezuelan and eastern equine encephalitis viruses.

Jennifer E. Golden, C. Jonsson, D. Chung, 2019, Antiviral research.

Benzamidine ML336 inhibits plus and minus strand RNA synthesis of Venezuelan equine encephalitis virus without affecting host RNA production.

Jennifer E. Golden, C. Jonsson, D. Chung, 2019, Antiviral research.

Novel VEEV RNA synthesis inhibitor

Jennifer E. Golden, C. Jonsson, D. Chung, 2018 .

Optimization of Potent and Selective Quinazolinediones: Inhibitors of Respiratory Syncytial Virus That Block RNA-Dependent RNA-Polymerase Complex Activity

Chad E. Schroeder, Jennifer E. Golden, R. Plemper, 2014, Journal of medicinal chemistry.

Heterotypic protection following oral immunization with live heterologous rotaviruses in a mouse model.

H. Greenberg, D. Chung, N. Feng, 1997, The Journal of infectious diseases.

Non-catastrophic collapse of VEEV by lethal mutagenesis

Juw Won Park, D. Chung, M. Smith, 2022, bioRxiv.

The Murine Model for Hantaan Virus-Induced Lethal Disease Shows Two Distinct Paths in Viral Evolutionary Trajectory with and without Ribavirin Treatment

S. Remold, C. Bruder, C. Jonsson, 2013, Journal of Virology.

Treatment Trajectory with and without Ribavirin Distinct Paths in Viral Evolutionary Virus-Induced Lethal Disease Shows Two The Murine Model for Hantaan

S. Remold, C. Jonsson, D. Chung, 2013 .

Ribavirin Reveals a Lethal Threshold of Allowable Mutation Frequency for Hantaan Virus

Al Bartolucci, Yanjie Sun, Colleen B. Jonsson, 2007, Journal of Virology.

ML336: Development of Quinazolinone-Based Inhibitors Against Venezuelan Equine Encephalitis Virus (VEEV)

Jennifer E. Golden, Nichole A. Tower, D. Chung, 2013 .

Piperazinobenzodiazepinones: New Encephalitic Alphavirus Inhibitors via Ring Expansion of 2-Dichloromethylquinazolinones

Jennifer E. Golden, J. Baudry, C. Jonsson, 2022, ACS medicinal chemistry letters.

High-Throughput Screening of a 100,000-Compound Library for Inhibitors of Influenza A Virus (H3N2)

M. McDowell, C. Jonsson, D. Chung, 2008, Journal of biomolecular screening.

Advanced Safety and Genetic Stability in Mice of a Novel DNA-Launched Venezuelan Equine Encephalitis Virus Vaccine with Rearranged Structural Genes

I. Lukashevich, D. Chung, Y. Chu, 2020, Vaccines.

Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients

L. Wolf, J. Chariker, E. Rouchka, 2021, Scientific Reports.

Rapid Sequencing of Multiple RNA Viruses in Their Native Form

I. Nookaew, D. Ussery, C. Jonsson, 2018, bioRxiv.

Plant-derived exosomal microRNAs inhibit lung inflammation induced by exosomes SARS-CoV-2 Nsp12

Xin Hu, M. Merchant, C. McClain, 2021, Molecular Therapy.

The Establishment of an Antiviral State by Pyrimidine Synthesis Inhibitor is Cell Type-Specific

D. Chung, 2015, Journal of antimicrobial agents.

A rapid assessment of wastewater for genomic surveillance of SARS-CoV-2 variants at sewershed scale in Louisville, KY

J. Chariker, E. Rouchka, W. Zacharias, 2021, medRxiv.

Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesis of the Yersinia-Containing Vacuole To Avoid Killing by Macrophages

E. Rouchka, D. Chung, M. Lawrenz, 2018, mBio.

Efficacy of a brain-penetrant antiviral in lethal Venezuelan and eastern equine encephalitis mouse models

Jennifer E. Golden, B. Meibohm, C. Jonsson, 2023, Science Translational Medicine.

Variant analysis of 1,040 SARS-CoV-2 genomes

J. Chariker, E. Rouchka, D. Chung, 2020, PloS one.

Critical insights into the pathogenesis of clinical isolates of pandemic influenza A(H1N1) 2009 virus in mouse and ferret models.

D. Chung, Y. Chu, Camp, 2015 .

A Cell Based HTS Approach for the Discovery of New Inhibitors of RSV

Jennifer E. Golden, Nichole A. Tower, C. Jonsson, 2013 .

Identification of a Series of Quinazolinediones as Potent, Selective, Post-Entry Inhibitors of Human Respiratory Syncytial Virus ( h RSV) via a Cell-Based High Throughput Screen and Chemical Optimization

Jennifer E. Golden, Nichole A. Tower, Carrie W. Evans, 2013 .

Dynein-Dependent Transport of the Hantaan Virus Nucleocapsid Protein to the Endoplasmic Reticulum-Golgi Intermediate Compartment

M. McDowell, C. Jonsson, Harish N. Ramanathan, 2007, Journal of Virology.

HTS-Driven Discovery of New Chemotypes with West Nile Virus Inhibitory Activity

Qianjun Li, C. Jonsson, D. Chung, 2010, Molecules.