S. Unzai

发表

Crystal Structure of Human Importin-α1 (Rch1), Revealing a Potential Autoinhibition Mode Involving Homodimerization

H. Miyatake, Y. Aida, N. Dohmae, 2015, PloS one.

Title Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning : Structural Role for eIF 3 c and Its Control by eIF 5

R. E. Luna, E. Papadopoulos, J. P. Erzberger, 2019 .

Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.

R. E. Luna, E. Papadopoulos, J. P. Erzberger, 2017, Cell reports.

The nature of the TRAP–Anti-TRAP complex

J. Tame, Sam-Yong Park, Masahiro Watanabe, 2009, Proceedings of the National Academy of Sciences.

Self-Assembling Nano-Architectures Created from a Protein Nano-Building Block Using an Intermolecularly Folded Dimeric de Novo Protein.

M. Hecht, Takaaki Sato, R. Arai, 2015, Journal of the American Chemical Society.

Computational design of a self-assembling symmetrical β-propeller protein

Hiroki Noguchi, Kam Y. J. Zhang, David Simoncini, 2014, Proceedings of the National Academy of Sciences.

Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacterium

Y. Ikegaya, M. Iseki, Tetsuo Takahashi, 2016, Proceedings of the National Academy of Sciences.

Interaction and Stoichiometry of the Peripheral Stalk Subunits NtpE and NtpF and the N-terminal Hydrophilic Domain of NtpI of Enterococcus hirae V-ATPase*

S. Yokoyama, S. Iwata, T. Terada, 2008, Journal of Biological Chemistry.

Crystal Structures of the Liganded and Unliganded Nickel-binding Protein NikA from Escherichia coli*

J. Tame, Sam-Yong Park, J. Heddle, 2003, Journal of Biological Chemistry.

Crystal structure of basic 7S globulin, a xyloglucan‐specific endo‐β‐1,4‐glucanase inhibitor protein‐like protein from soybean lacking inhibitory activity against endo‐β‐glucanase

H. Hirano, Toshiyuki Shimizu, H. Hashimoto, 2011, The FEBS journal.

Crystal structures of the catalytic domains of pseudouridine synthases RluC and RluD from Escherichia coli.

J. Tame, Sam-Yong Park, S. Unzai, 2004, Biochemistry.

Structural basis for the dual RNA-recognition modes of human Tra2-β RRM

Sumio Sugano, Peter Güntert, Satoru Watanabe, 2010, Nucleic acids research.

Solution structure of Gaussia Luciferase with five disulfide bonds and identification of a putative coelenterazine binding cavity by heteronuclear NMR

N. Kobayashi, N. Wu, S. Unzai, 2020, Scientific Reports.

Investigation of molecular size of transcription factor TFIIE in solution

S. Akashi, Y. Nishimura, S. Unzai, 2005, Proteins.

EGFR extracellular domain III expressed in Escherichia coli with SEP tag shows improved biophysical and functional properties and generate anti-sera inhibiting cancer cell growth.

S. Unzai, Y. Kuroda, M. G. Kibria, 2021, Biochemical and biophysical research communications.

Purification, crystallization and initial X-ray diffraction study of human REV7 in complex with a REV3 fragment

Hashimoto, S. Akashi, Toshiyuki Shimizu, 2009 .

Role of domains within the autotransporter Hbp/Tsh.

J. Tame, Sam-Yong Park, S. Unzai, 2010, Acta crystallographica. Section D, Biological crystallography.

Blocking PSD95‐PDZ3's amyloidogenesis through point mutations that inhibit high‐temperature reversible oligomerization (RO)

Jose C. Martínez, K. Noguchi, S. Kidokoro, 2021, The FEBS journal.

A systematic mutational analysis identifies a 5‐residue proline tag that enhances the in vivo immunogenicity of a non‐immunogenic model protein

Mohammad M. Islam, S. Unzai, Y. Kuroda, 2020, FEBS open bio.

A systematic mutational analysis identifies a 5‐residue proline tag that enhances the in vivo immunogenicity of a non‐immunogenic model protein

Mohammad M. Islam, S. Unzai, Y. Kuroda, 2020, bioRxiv.

Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, both in the native form and covalently linked to various antibiotics.

J. Tame, Sam-Yong Park, A. Lloyd, 2006, Biochemistry.

Novel Mechanisms of pH Sensitivity in Tuna Hemoglobin

J. Tame, Sam-Yong Park, H. Morimoto, 2004, Journal of Biological Chemistry.

Mutagenic Studies on the Origins of the Root Effect

K. Nagai, J. Tame, Sam-Yong Park, 2008 .

Thermodynamic Analysis of Point Mutations Inhibiting High-Temperature Reversible Oligomerization of PDZ3.

Jose C. Martínez, S. Kidokoro, S. Unzai, 2020, Biophysical journal.

Thermodynamic analysis of point mutations inhibiting high-temperature reversible oligomer of PDZ3

S. Kidokoro, S. Unzai, J. C. Martínez, 2020, bioRxiv.

Crystal structure of MytiLec, a galactose-binding lectin from the mussel Mytilus galloprovincialis with cytotoxicity against certain cancer cell types

F. Kawai, J. Tame, Sam-Yong Park, 2016, Scientific Reports.

Analytical ultracentrifugation in structural biology

Satoru Unzai, S. Unzai, 2018, Biophysical Reviews.

Fission Yeast Swi5-Sfr1 Protein Complex, an Activator of Rad51 Recombinase, Forms an Extremely Elongated Dogleg-shaped Structure

M. Ikeguchi, S. Akashi, Toshiyuki Shimizu, 2011, The Journal of Biological Chemistry.

The Swi5–Sfr1 complex stimulates Rhp51/Rad51 - and Dmc1-mediated DNA strand exchange in vitro

Y. Tsutsui, S. Unzai, Y. Kurokawa, 2006, Nature Structural &Molecular Biology.

Fine-tuning of protein domain boundary by minimizing potential coiled coil regions

M. Shirakawa, K. Tomii, H. Tochio, 2006, Journal of biomolecular NMR.

RBFOX and SUP-12 sandwich a G base to cooperatively regulate tissue-specific splicing

P. Güntert, M. Hagiwara, S. Yokoyama, 2014, Nature Structural &Molecular Biology.

Structural insights into a 20.8-kDa tegumental-allergen-like (TAL) protein from Clonorchis sinensis

Sam-Yong Park, K. Hwang, S. Unzai, 2017, Scientific Reports.

Insight into structural diversity of influenza virus haemagglutinin.

Sam-Yong Park, Chul-Joong Kim, X. Saelens, 2013, The Journal of general virology.

Crystal structure of elongation factor P from Thermus thermophilus HB8.

S. Yokoyama, J. Tame, T. Terada, 2004, Proceedings of the National Academy of Sciences of the United States of America.

A novel 3′ splice site recognition by the two zinc fingers in the U2AF small subunit

E. Obayashi, H. Yoshida, Sam-Yong Park, 2015, Genes & development.

Structures of haemoglobin from woolly mammoth in liganded and unliganded states.

C. Ho, J. Tame, Sam-Yong Park, 2012, Acta crystallographica. Section D, Biological crystallography.

Oxygen Equilibrium Properties of Chromium(III)-Iron(II) Hybrid Hemoglobins (*)

N. Shibayama, H. Morimoto, S. Unzai, 1996, The Journal of Biological Chemistry.

Rate Constants for O2 and CO Binding to the α and β Subunits within the R and T States of Human Hemoglobin*

N. Shibayama, H. Morimoto, J. Olson, 1998, The Journal of Biological Chemistry.

Crystal Structure of Human REV7 in Complex with a Human REV3 Fragment and Structural Implication of the Interaction between DNA Polymerase ζ and REV1*

Y. Murakumo, S. Akashi, Toshiyuki Shimizu, 2010, The Journal of Biological Chemistry.

A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation

P. V. von Hippel, P. Prevelige, R. Fairman, 2015, PloS one.

Crystal Structure of the Ubiquitin-associated (UBA) Domain of p62 and Its Interaction with Ubiquitin*

M. Shirakawa, Keiji Tanaka, M. Komatsu, 2011, The Journal of Biological Chemistry.

Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

S. Yokoyama, J. Tame, Sam-Yong Park, 2005 .

Structural and functional characterization of the NHR1 domain of the Drosophila neuralized E3 ligase in the notch signaling pathway.

O. Ohara, P. Güntert, T. Kigawa, 2009, Journal of molecular biology.

Relationship between heat-induced fibrillogenicity and hemolytic activity of thermostable direct hemolysin and a related hemolysin of Vibrio parahaemolyticus.

K. Shiraki, H. Hashimoto, T. Honda, 2011, FEMS microbiology letters.

Relationship between heat-induced ¢ brillogenicityand hemolytic activityofthermostabledirect hemolysinanda relatedhemolysinof Vibrio parahaemolyticus

K. Shiraki, H. Hashimoto, T. Honda, 2011 .

Expression, purification and crystallization of Swi5 and the Swi5-Sfr1 complex from fission yeast.

M. Ikeguchi, Toshiyuki Shimizu, H. Hashimoto, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Oligomerization of Hmo1 mediated by box A is essential for DNA binding in vitro and in vivo

H. Yoshikawa, S. Unzai, T. Kokubo, 2016, Genes to cells : devoted to molecular & cellular mechanisms.

Crystal Structure of 4-(Cytidine 5′-diphospho)-2-C-methyl-d-erythritol kinase, an Enzyme in the Non-mevalonate Pathway of Isoprenoid Synthesis*

S. Yokoyama, J. Tame, Sam-Yong Park, 2003, Journal of Biological Chemistry.

Structure and catalytic mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MECDP) synthase, an enzyme in the non-mevalonate pathway of isoprenoid synthesis.

S. Yokoyama, J. Tame, Sam-Yong Park, 2003, Acta crystallographica. Section D, Biological crystallography.

Structure and mechanism of HpcG, a hydratase in the homoprotocatechuate degradation pathway of Escherichia coli.

J. Tame, Sam-Yong Park, S. Unzai, 2007, Journal of molecular biology.

Decreased amyloidogenicity caused by mutational modulation of surface properties of the immunoglobulin light chain BRE variable domain.

H. Kamikubo, M. Kataoka, S. Unzai, 2014, Biochemistry.

Crystal structure of zinc‐finger domain of Nanos and its functional implications

Toshiyuki Shimizu, H. Hashimoto, S. Unzai, 2010, EMBO reports.

Nanometer-size aggregates generated using short Solubility Controlling Peptide tags do increase the in vivo immunogenicity of a non-immunogenic protein.

Mohammad M. Islam, S. Unzai, Y. Kuroda, 2020, Molecular pharmaceutics.

Generation of “nanometer-size aggregates” using Solubility Controlling Peptide tags and their ability to increase a protein’s immunogenicity in vivo

Mohammad M. Islam, S. Unzai, Y. Kuroda, 2019 .

AU‐rich RNA‐binding induces changes in the quaternary structure of AUH

C. Robinson, S. Yokoyama, Y. Muto, 2009, Proteins.

Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae.

Thomas B. Clarke, E. Obayashi, F. Kawai, 2010, Journal of molecular biology.

Crystal structure of the UBA domain of p62 and its interaction with ubiquitin

M. Shirakawa, Keiji Tanaka, M. Komatsu, 2011 .

Cloning, expression and purification of cytochrome c(6) from the brown alga Hizikia fusiformis and complete X-ray diffraction analysis of the structure.

F. Kawai, Sam-Yong Park, T. Nishio, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystal structure of human REV 7 in complex with a human REV 3 fragment and structural implication of the interaction between DNA polymerase ζ and REV 1

Y. Murakumo, S. Akashi, Toshiyuki Shimizu, 2010 .

Heat‐induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light‐chain REI

H. Kamikubo, M. Kataoka, Tsutomu Nakamura, 2017, The FEBS journal.

The structure and conformational switching of Rap1B.

T. Ikegami, J. Tame, Sam-Yong Park, 2015, Biochemical and biophysical research communications.

Reversible oligomerization and reverse hydrophobic effect induced by isoleucine tags attached at the C-terminus of a simplified BPTI variant.

S. Kidokoro, S. Unzai, Y. Kuroda, 2020, Biochemistry.

Crystal structure of oxidized cytochrome c 6A from Arabidopsis thaliana

F. Kawai, Sam-Yong Park, T. Nishio, 2006, FEBS letters.

Oligomerization of Hmo1 mediated by box A is essential for DNA binding in vitro and in vivo

H. Yoshikawa, S. Unzai, T. Kokubo, 2016, Genes to cells : devoted to molecular & cellular mechanisms.

Self-Assembling Nano-Architectures Created from a Protein Nano-Building Block Using an Intermolecularly Folded Dimeric de Novo Protein.

M. Hecht, Takaaki Sato, R. Arai, 2015, Journal of the American Chemical Society.

Structures of haemoglobin from woolly mammoth in liganded and unliganded states.

C. Ho, J. Tame, Sam-Yong Park, 2012, Acta crystallographica. Section D, Biological crystallography.

Unusual thermal disassembly of the SPFH domain oligomer from Pyrococcus horikoshii.

T. Ikegami, Y. Hiroaki, Y. Fujiyoshi, 2009, Biophysical journal.

Decreased amyloidogenicity caused by mutational modulation of surface properties of the immunoglobulin light chain BRE variable domain.

H. Kamikubo, M. Kataoka, S. Unzai, 2014, Biochemistry.

Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.

R. E. Luna, E. Papadopoulos, A. Hinnebusch, 2017, Cell reports.

1P034 Novel Mechanisms of pH sensitivity in tuna hemoglobin : a structural explanation of the Root effect

J. Tame, H. Morimoto, K. T. Chong, 2004 .