I. Lim

发表

Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells.

T. Park, S. H. Park, I. Lim, 2011, Experimental cell research.

TIS21/BTG2/PC3 is expressed through PKC-delta pathway and inhibits binding of cyclin B1-Cdc2 and its activity, independent of p53 expression.

Jong-Wook Hong, T. Hahn, I. Lim, 2004, Experimental cell research.

Phosphorylation of methylated-DNA-protein-cysteine S-methyltransferase at serine-204 significantly increases its resistance to proteolytic digestion.

T. Park, I. Lim, W. Paik, 2000 .

Induction of thermal and chemical stability of O6-methylguanine-DNA methyltransferase by Ca2+.

T. Park, I. Lim, W. Paik, 2002, Biochimica et biophysica acta.

Methylation of O6‐methylguanine‐DNA methyltransferase gene is associated significantly with K‐ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma

T. Park, I. Lim, W. Paik, 2001, Cancer.

Phosphorylation of Serine 147 of tis21/BTG2/pc3 by p-Erk1/2 Induces Pin-1 Binding in Cytoplasm and Cell Death*

Jong-Wook Hong, I. Lim, M. S. Ryu, 2005, Journal of Biological Chemistry.

B-cell translocation gene 2: Expression in the rat ovary and potential association with adenine nucleotide translocase 2 in mitochondria

T. Park, S. Chun, I. Lim, 2013, Molecular and Cellular Endocrinology.

Mitochondrial nucleoid remodeling and biogenesis are regulated by the p53-p21-PKCζ pathway in p16-silenced cells

Yun Yeong Lee, I. Lim, M. S. Ryu, 2020 .

Biological methylation of myelin basic protein: enzymology and biological significance.

I. Lim, G. Park, W. Paik, 1997, The international journal of biochemistry & cell biology.

TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1–Forkhead box M1 regulation loop

H. Wang, J. Y. Kim, T. Park, 2008, Hepatology.

Translocational Inefficiency of Intracellular Proteins in Senescence of Human Diploid Fibroblasts

G. Yoon, S. Park, I. Lim, 2001, Annals of the New York Academy of Sciences.

Signals regulating necrosis of cardiomyoblast by BTG2(/TIS21/PC3) via activation of GSK3β and opening of mitochondrial permeability transition pore in response to H2O2.

Y. Choi, T. Park, Hyo‐Soo Kim, 2013, Biochemical and biophysical research communications.

C-terminus-deleted FoxM1 is expressed in cancer cell lines and induces chromosome instability.

Young Hwa Kim, J. Kim, T. Park, 2013, Carcinogenesis.

Translational downregulation of Twist1 expression by antiproliferative gene, B-cell translocation gene 2, in the triple negative breast cancer cells

A. Jayabalan, T. Ohn, I. Lim, 2019, Cell Death & Disease.

Phosphorylation of methylated-DNA-protein-cysteine S-methyltransferase at serine-204 significantly increases its resistance to proteolytic digestion.

T. Park, I. Lim, W. Paik, 2000, The Biochemical journal.

Enhanced glycogenesis is involved in cellular senescence via GSK3/GS modulation

G. Yoon, H. Chung, I. Lim, 2008, Aging cell.

Regulation of selection of liver nodules initiated with N‐nitrosodiethylamine and promoted with nodularin injections in Fischer 344 male rats by reciprocal expression of transforming growth factor‐β1 and its receptors

Seong-Jin Kim, T. Park, S. Kim, 1999, Molecular carcinogenesis.

Phosphorylated Extracellular Signal-regulated Protein Kinases 1 and 2 Phosphorylate Sp1 on Serine 59 and Regulate Cellular Senescence via Transcription of p21Sdi1/Cip1/Waf1*

I. Lim, H. Kim, 2009, The Journal of Biological Chemistry.

Formation of elongated giant mitochondria in DFO‐induced cellular senescence: Involvement of enhanced fusion process through modulation of Fis1

Young-sil Yoon, G. Yoon, H. Chung, 2006, Journal of cellular physiology.

Alkylguanine-DNA Alkyltransferase 6 O Retrovirally Mediated Gene Transfer of Bacterial Increase in Nitrosourea Resistance in Mammalian Cells by Updated Version

M. Hatzoglou, S. Abboud, S. Gerson, 2006 .

Changes in the expression of cell cycle regulators during rat liver regeneration after partial hepatectomy

I. Lim, Hyeseong Cho, Jae‐Ho Lee, 1996, Experimental & Molecular Medicine.

Accumulation of cytolytic CD8+ T cells in B16-melanoma and proliferation of mature T cells in TIS21-knockout mice after T cell receptor stimulation.

Sun Park, I. Lim, M. S. Ryu, 2014, Experimental cell research.

Induction of growth inhibition of 293 cells by downregulation of the cyclin E and cyclin‐dependent kinase 4 proteins due to overexpression of TIS21

T. Park, I. Lim, H. Fujiki, 1998, Molecular carcinogenesis.

Expression of androgen receptor and its implication in hepatoma cells.

I. Lim, H. Cho, 1997, Cancer letters.

TIS21(/BTG2/PC3) accelerates the repair of DNA double strand breaks by enhancing Mre11 methylation and blocking damage signal transfer to the Chk2(T68)-p53(S20) pathway.

J. Y. Kim, Y. Choi, Young Hwa Kim, 2012, DNA repair.

Phylogenetic characterization of norovirus strains detected from sporadic gastroenteritis in Seoul during 2014–2016

T. Park, I. Lim, Miok Song, 2018, Gut Pathogens.

Identification of highly methylated arginine residues in an endogenous 20-kDa polypeptide in cancer cells.

H. W. Lee, I. Lim, G. Park, 1999, Life sciences.

ICE‐like protease (caspase) is involved in transforming growth factor β1–mediated apoptosis in FaO rat hepatoma cell line

J. Brady, Seong-Jin Kim, K. Choi, 1998, Hepatology.

Marked inhibition of testosterone biosynthesis by the hepatotoxin nodularin due to apoptosis of Leydig cells

T. Park, I. Lim, K. Song, 2002, Molecular carcinogenesis.

Selective left‐lobe atrophy by nodularin treatment accompanied by reduced protein phosphatase 1/2a and increased peroxisome proliferation in rat liver

G. Yoon, S. Park, T. Park, 2001, International journal of cancer.

Compartmental inhibition of hepatic glutathione reductase activities by 1,3-bis(2-chloroethyl)-N-nitrosourea (BCNU) in Sprague-Dawley and Fischer-344 rats.

I. Lim, C. Backes, L. Rogers, 2004, Toxicology letters.

Friendship in research: the Japan–Korea symposia on cancer and ageing

S. Park, Y. Yuasa, I. Lim, 2008, Journal of Cancer Research and Clinical Oncology.

Experimental Oncology Differential expression of TIS21 and TIS1 genes in the various organs of Balb/c mice, thymic carcinoma tissues and human cancer cell lines

N. Kim, Jeong-Sun Seo, S. Park, 2005, Journal of Cancer Research and Clinical Oncology.

Nuclear Accumulation of Globular Actin as a Cellular Senescence Marker

I. Lim, M. S. Ryu, H. Kim, 2004, Cancer Research.

Pleiotrophin inhibits transforming growth factor β1‐induced apoptosis in hepatoma cell lines

K. Yoshizato, T. Park, I. Lim, 2008, Molecular carcinogenesis.

TIS21/BTG2 inhibits doxorubicin-induced stress fiber-vimentin networks via Nox4-ROS-ABI2-DRF-linked signal cascade.

Sang‐Hee Shim, E. Y. Kim, I. Lim, 2017, Cellular signalling.

Methylation of O(6)-methylguanine-DNA methyltransferase gene is associated significantly with K-ras mutation, lymph node invasion, tumor staging, and disease free survival in patients with gastric carcinoma.

T. Park, I. Lim, W. Paik, 2001, Cancer.

Iron chelation-induced senescence-like growth arrest in hepatocyte cell lines: association of transforming growth factor beta1 (TGF-beta1)-mediated p27Kip1 expression.

Young-sil Yoon, G. Yoon, I. Lim, 2002, The Biochemical journal.

High level, regulated expression of the chimeric P-enolpyruvate carboxykinase (GTP)-bacterial O6-alkylguanine-DNA alkyltransferase (ada) gene in transgenic mice.

T. Wagner, S. Gerson, I. Lim, 1990, Cancer research.

Proper regulation of β-adrenergic signal requires Btg2 gene for lipolysis and thermogenesis in response to starvation or cold acclimation in female mice.

I. Lim, M. S. Ryu, A. E. Hong, 2022, The Journal of nutritional biochemistry.

Protection of 5α‐dihydrotestosterone against TGF‐β‐induced apoptosis in FaO cells and induction of mitosis in HepG2 cells

K. Choi, I. Lim, H. Fujiki, 1997 .

Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: Induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and methylation of p16INK4A exon 1 in hepatocellular carcinoma

Yun‐Sil Lee, Y. Lee, J. Jang, 2001, Molecular carcinogenesis.

Protein Methylation and Interaction with the Antiproliferative Gene, BTG2/TIS21/Pc3

I. Lim, W. Paik, Sangduk Kim, 2014, Yonsei medical journal.

TIS21/BTG2 inhibits invadopodia formation by downregulating reactive oxygen species level in MDA-MB-231 cells

I. Lim, Jung-A Choi, 2013, Journal of Cancer Research and Clinical Oncology.

Erratum to “Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats” [Mechanisms of Ageing and Development 123 (2002) 1665–1680]

I. Lim, 2003, Mechanisms of Ageing and Development.

Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats

I. Lim, 2002, Mechanisms of Ageing and Development.

Inhibition of bladder cancer invasion by Sp1‐mediated BTG2 expression via inhibition of DNA methyltransferase 1

Wun-Jae Kim, Y. Choi, S. Sheen, 2014, The FEBS journal.

Role of TNF-α-Inducing Protein Secreted by Helicobacter pylori as a Tumor Promoter in Gastric Cancer and Emerging Preventive Strategies

Tatsuro Watanabe, I. Lim, H. Fujiki, 2021, Toxins.

Increase in nitrosourea resistance in mammalian cells by retrovirally mediated gene transfer of bacterial O6-alkylguanine-DNA alkyltransferase.

M. Hatzoglou, S. Abboud, S. Gerson, 1989, Cancer research.

Downregulation of PEA-15 reverses G1 arrest, and nuclear and chromatin changes of senescence phenotype via pErk1/2 translocation to nuclei.

Yun Yeong Lee, I. Lim, H. Kim, 2015, Cellular signalling.

Constitutive Induction of p-Erk1/2 Accompanied by Reduced Activities of Protein Phosphatases 1 and 2A and MKP3 Due to Reactive Oxygen Species during Cellular Senescence*

T. Park, I. Lim, H. Kim, 2003, Journal of Biological Chemistry.

TIS21/BTG2 inhibits breast cancer growth and progression by differential regulation of mTORc1 and mTORc2–AKT1–NFAT1–PHLPP2 signaling axis

D. Noh, I. Lim, M. S. Ryu, 2018, Journal of Cancer Research and Clinical Oncology.

Inhibition of TNFα-interacting protein α (Tipα)-associated gastric carcinogenesis by BTG2/TIS21 via downregulating cytoplasmic nucleolin expression

Tatsuro Watanabe, I. Lim, M. Suganuma, 2018, Experimental & Molecular Medicine.

Inhibition of breast cancer invasion by TIS21/BTG2/Pc3-Akt1-Sp1-Nox4 pathway targeting actin nucleators, mDia genes

I. Lim, H. Kim, Y. S. Jung, 2016, Oncogene.

TIS21(/BTG2/PC3) inhibits interleukin-6 expression via downregulation of STAT3 pathway.

Y. Choi, T. Park, Y. Chwae, 2013, Cellular signalling.

B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NFκB pathways which enhances transcription of MnSOD by accelerating IκBα degradation in normal and cancer cells

I. Lim, M. S. Ryu, Santhoshkumar Sundaramoorthy, 2013, Cell Communication and Signaling.

BTG2 suppresses cancer cell migration through inhibition of Src-FAK signaling by downregulation of reactive oxygen species generation in mitochondria

Y. Choi, T. Park, I. Lim, 2012, Clinical & Experimental Metastasis.

Skp2 enhances polyubiquitination and degradation of TIS21/BTG2/PC3, tumor suppressor protein, at the downstream of FoxM1.

J. Y. Kim, T. Park, S. H. Park, 2009, Experimental cell research.

B Cell Translocation Gene 2 Enhances Susceptibility of HeLa Cells to Doxorubicin-induced Oxidative Damage*

T. Park, I. Lim, Youngho Lim, 2008, Journal of Biological Chemistry.

TIS21/BTG2 Negatively Regulates Estradiol‐Stimulated Expansion of Hematopoietic Stem Cells by Derepressing Akt Phosphorylation and Inhibiting mTOR Signal Transduction

S. P. Oh, I. Lim, M. S. Ryu, 2008, Stem cells.

TIS21/BTG2/PC3 as a link between ageing and cancer: cell cycle regulator and endogenous cell death molecule

I. Lim, In Kyoung Lim, 2006, Journal of Cancer Research and Clinical Oncology.

Cytoplasmic retention of p-Erk1/2 and nuclear accumulation of actin proteins during cellular senescence in human diploid fibroblasts

G. Yoon, S. Park, I. Lim, 2000, Mechanisms of Ageing and Development.

Subcellular redistribution of protein kinase C isozymes is associated with rat liver cirrhotic changes induced by carbon tetrachloride or thioacetamide

K. Jeong, Yun‐Sil Lee, Ja-june Jang, 2001, Journal of gastroenterology and hepatology.

Stress-induced NF-κB activation differentiates promyelocytic leukemia cells to macrophages in response to all-trans-retinoic acid.

Joon Seong Park, I. Lim, Muhammad Imran, 2015, Cellular signalling.

Regulation of Btg2(/TIS21/PC3) expression via reactive oxygen species-protein kinase C-ΝFκΒ pathway under stress conditions.

I. Lim, Muhammad Imran, 2013, Cellular signalling.

Loss of p21(Sdi1) expression in senescent cells after DNA damage accompanied with increase of miR-93 expression and reduced p53 interaction with p21(Sdi1) gene promoter.

I. Lim, Ok Ran Choi, 2011, Biochemical and biophysical research communications.

Shifting p53-induced senescence to cell death by TIS21(/BTG2/Pc3) gene through posttranslational modification of p53 protein.

I. Lim, M. S. Ryu, Ok Ran Choi, 2016, Cellular signalling.

Direct activation of TGF‐β1 transcription by androgen and androgen receptor complex in Huh7 human hepatoma cells and its tumor in nude mice

G. Yoon, I. Lim, Young‐Suk Won, 2006, Journal of cellular biochemistry.

Sensitization of metformin-cytotoxicity by dichloroacetate via reprogramming glucose metabolism in cancer cells.

Y. Choi, I. Lim, 2014, Cancer letters.

C‐reactive protein induces G2/M phase cell cycle arrest and apoptosis in monocytes through the upregulation of B‐cell translocation gene 2 expression

I. Lim, M. S. Ryu, Jewon Ryu, 2014, FEBS letters.

Differential expression of O 6-methylguanine-DNA methyltransferase during diethylnitrosamine-induced carcinogenesis and liver regeneration in Sprague-Dawley male rats

T. Park, I. Lim, M. Lee, 1999, Journal of Cancer Research and Clinical Oncology.

Regulations of Reversal of Senescence by PKC Isozymes in Response to 12-O-Tetradecanoylphorbol-13-Acetate via Nuclear Translocation of pErk1/2

Yun Yeong Lee, I. Lim, M. Suganuma, 2016, Molecules and cells.

BTG2 suppresses cancer cell migration through inhibition of Src-FAK signaling by downregulation of reactive oxygen species generation in mitochondria

T. Park, I. Lim, Seo-Kyung Lim, 2012, Clinical & Experimental Metastasis.

TIS21/BTG2/PC3 enhances downregulation of c-Myc during differentiation of HL-60 cells by activating Erk1/2 and inhibiting Akt in response to all-trans-retinoic acid.

T. Park, I. Lim, Muhammad Imran, 2012, European journal of cancer.

Translational downregulation of Twist1 expression by antiproliferative gene, B-cell translocation gene 2, in the triple negative breast cancer cells

A. Jayabalan, T. Ohn, I. Lim, 2019, Cell Death & Disease.

Synaptotagmin IV is an immediate early gene induced by depolarization in PC12 cells and in brain.

M. Baudry, G. Tocco, H. Herschman, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Two synaptotagmin genes, Syt1 and Syt4, are differentially regulated in adult brain and during postnatal development following kainic acid-induced seizures.

M. Baudry, X. Bi, G. Tocco, 1996, Brain research. Molecular brain research.

Enhanced glycogenesis is involved in cellular senescence via GSK3/GS modulation

G. Yoon, H. Chung, I. Lim, 2008, Aging cell.

Inhibition of bladder cancer invasion by Sp1‐mediated BTG2 expression via inhibition of DNA methyltransferase 1

Wun-Jae Kim, Y. Choi, S. Sheen, 2014, The FEBS journal.

TIS21/BTG2 inhibits doxorubicin-induced stress fiber-vimentin networks via Nox4-ROS-ABI2-DRF-linked signal cascade.

E. Y. Kim, I. Lim, M. S. Ryu, 2017, Cellular signalling.