T. T. Poulsen

发表

In vitro and in vivo effects of polyethylene glycol (PEG)-modified lipid in DOTAP/cholesterol-mediated gene transfection

J. Roth, C. Christensen, T. Gjetting, 2010, International journal of nanomedicine.

Insertion of a nuclear factor kappa B DNA nuclear-targeting sequence potentiates suicide gene therapy efficacy in lung cancer cell lines

C. Christensen, D. Dean, T. T. Poulsen, 2012, Cancer Gene Therapy.

Replacement and suicide gene therapy for targeted treatment of lung cancer.

N. Pedersen, T. T. Poulsen, H. Poulsen, 2005, Clinical lung cancer.

Targeted Cytosine Deaminase-Uracil Phosphoribosyl Transferase Suicide Gene Therapy Induces Small Cell Lung Cancer–Specific Cytotoxicity and Tumor Growth Delay

J. Roth, C. Christensen, T. Gjetting, 2010, Clinical Cancer Research.

Efficacy of Sym 004 in PatientsWithMetastatic Colorectal CancerWith Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNAAnalyses A Phase 2 Randomized Clinical Trial

C. Nadal, R. Salazar, A. Bardelli, 2018 .

Molecular biology of lung cancer

H. Pappot, T. T. Poulsen, H. Poulsen, 2008 .

In vivo imaging of therapy response to a novel Pan-HER antibody mixture using FDG and FLT positron emission tomography

C. H. Nielsen, A. Kjaer, Mette Jensen, 2015, Oncotarget.

Specific sensitivity of small cell lung cancer cell lines to the snake venom toxin taipoxin.

N. Pedersen, T. T. Poulsen, H. Poulsen, 2005, Lung cancer.

Single agent‐ and combination treatment with two targeted suicide gene therapy systems is effective in chemoresistant small cell lung cancer cells

M. Sehested, C. Christensen, T. T. Poulsen, 2012, The journal of gene medicine.

Cre-loxP recombination vectors for promoter studies

N. Pedersen, T. T. Poulsen, H. Poulsen, 2007 .

Pan-HER, an Antibody Mixture Simultaneously Targeting EGFR, HER2, and HER3, Effectively Overcomes Tumor Heterogeneity and Plasticity

D. Weilguny, B. Bjerregaard, T. T. Poulsen, 2015, Clinical Cancer Research.

HER-Family Ligands Promote Acquired Resistance to Trastuzumab in Gastric Cancer

J. Albanell, O. Arpí, S. Menéndez, 2019, Molecular Cancer Therapeutics.

CD4+ and CD8a+ PET imaging predicts response to novel PD-1 checkpoint inhibitor: studies of Sym021 in syngeneic mouse cancer models

C. H. Nielsen, A. Kjaer, C. Christensen, 2019, Theranostics.

Simultaneous Targeting of Two Distinct Epitopes on MET Effectively Inhibits MET- and HGF-Driven Tumor Growth by Multiple Mechanisms

G. Woude, Morag Park, T. T. Poulsen, 2017, Molecular Cancer Therapeutics.

Pan‐HER—An antibody mixture targeting EGFR, HER2 and HER3 abrogates preformed and ligand‐induced EGFR homo‐ and heterodimers

T. T. Poulsen, S. Brix, I. Horak, 2016, International journal of cancer.

Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses: A Phase 2 Randomized Clinical Trial

C. Nadal, R. Salazar, A. Bardelli, 2018, JAMA oncology.

Targeting Three Distinct HER2 Domains with a Recombinant Antibody Mixture Overcomes Trastuzumab Resistance

T. T. Poulsen, I. Horak, M. Kragh, 2015, Molecular Cancer Therapeutics.

A chimeric fusion of the hASH1 and EZH2 promoters mediates high and specific reporter and suicide gene expression and cytotoxicity in small cell lung cancer cells

N. Pedersen, T. T. Poulsen, H. Poulsen, 2008, Cancer Gene Therapy.

In vitro cytotoxicity of combinations of dichloroacetate with anticancer platinum compounds

T. T. Poulsen, H. Poulsen, K. Geissler, 2010, Clinical pharmacology : advances and applications.

International Journal of Nanomedicine Dovepress

J. Roth, C. Christensen, T. Gjetting, 2022 .

Sym015: A Highly Efficacious Antibody Mixture against MET-Amplified Tumors

T. T. Poulsen, I. Horak, Camilla Fröhlich, 2017, Clinical Cancer Research.

A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue.

T. Andresen, C. Christensen, T. Gjetting, 2011, Results in pharma sciences.

Acute damage by naphthalene triggers expression of the neuroendocrine marker PGP9.5 in airway epithelial cells.

T. T. Poulsen, H. Poulsen, R. Linnoila, 2008, Toxicology letters.

Safety and preliminary clinical activity of the MET antibody mixture, Sym015 in advanced non-small cell lung cancer (NSCLC) patients with MET amplification/exon 14 deletion (METAmp/Ex14∆).

R. Heist, E. Felip, A. Navarro, 2020 .

Acquired Resistance to a MET Antibody In Vivo Can Be Overcome by the MET Antibody Mixture Sym015

E. Petricoin, S. Boca, A. Kjaer, 2018, Molecular Cancer Therapeutics.

1019O Phase I studies of Sym021, an anti-PD-1 antibody, alone and in combination with Sym022 (anti-LAG-3) or Sym023 (anti-TIM-3)

A. Tolcher, F. Janku, T. T. Poulsen, 2020, Annals of Oncology.

A phase Ia/IIa trial of Sym015, a MET antibody mixture, in patients with advanced solid tumours

S. H. Lee, Yoon-Koo Kang, D. Camidge, 2019, Annals of Oncology.

328. Transcriptionally Targeted Cancer Gene Therapy for Small Cell Lung Cancer

M. Breslin, M. Lan, N. Pedersen, 2006 .

In vitro and in vivo effects of polyethylene glycol (PEG)-modified lipid in DOTAP/cholesterol-mediated gene transfection

J. Roth, C. Christensen, T. Gjetting, 2010, International journal of nanomedicine.

A simple protocol for preparation of a liposomal vesicle with encapsulated plasmid DNA that mediate high accumulation and reporter gene activity in tumor tissue.

T. Andresen, C. Christensen, T. Gjetting, 2011, Results in pharma sciences.

Clinical Pharmacology: Advances and Applications Dovepress in Vitro Cytotoxicity of Combinations of Dichloroacetate with Anticancer Platinum Compounds

T. T. Poulsen, K. Geissler, G. Hamilton, 2022 .