N. Cheung

发表

pH dependent high transfection efficiency of mouse neuroblastomas using TransFectin

E. Koay, K. W. Y. Chong, A. Lee, 2006, Journal of Neuroscience Methods.

Temporal transcriptomic profiling reveals cellular targets that govern survival in HOCl-mediated neuronal apoptosis.

M. Whiteman, A. Melendez, N. Cheung, 2010, Life sciences.

The pro-inflammatory oxidant hypochlorous acid induces Bax-dependent mitochondrial permeabilisation and cell death through AIF-/EndoG-dependent pathways.

J. Schantz, K. Sabapathy, M. Whiteman, 2007, Cellular signalling.

Hypochlorous acid induces apoptosis of cultured cortical neurons through activation of calpains and rupture of lysosomes

B. Bay, F. Sheu, R. Qi, 2006, Journal of neurochemistry.

Hypochlorous acid-mediated mitochondrial dysfunction and apoptosis in human hepatoma HepG2 and human fetal liver cells: role of mitochondrial permeability transition.

B. Halliwell, M. Whiteman, N. Cheung, 2005, Free radical biology & medicine.

Hydrogen sulphide: a novel inhibitor of hypochlorous acid-mediated oxidative damage in the brain?

P. Moore, M. Whiteman, N. Cheung, 2005, Biochemical and biophysical research communications.

Peroxynitrite mediates calcium‐dependent mitochondrial dysfunction and cell death via activation of calpains

Dean P. Jones, J. Schantz, B. Halliwell, 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Mechanism of Calcium Transport Across the Plasma Membrane of Bovine Chromaffin Cells

L. Kao, N. Cheung, 1990, Journal of neurochemistry.

Sulfatide-tenascin interaction mediates binding to the extracellular matrix and endocytic uptake of liposomes in glioma cells

W. Duan, S. Feng, N. Cheung, 2007, Cellular and Molecular Life Sciences.

Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity.

E. Melamed, O. Bernard, S. Gorodin, 1998, Proceedings of the National Academy of Sciences of the United States of America.

The novel neuromodulator hydrogen sulfide: an endogenous peroxynitrite ‘scavenger’?

B. Halliwell, P. Moore, M. Whiteman, 2004, Journal of neurochemistry.

Identification of p10 as a neurotoxic product generated from the proteolytic cleavage of the neuronal Cdk5 activator

B. Bay, R. Qi, Lisheng He, 2010, Journal of cellular biochemistry.

Comparative Microarray Analysis Identifies Commonalities in Neuronal Injury: Evidence for Oxidative Stress, Dysfunction of Calcium Signalling, and Inhibition of Autophagy–Lysosomal Pathway

P. Beart, N. Cheung, Y. Yap, 2015, Neurochemical Research.

Up‐regulation of endoplasmic reticulum stress‐related genes during the early phase of treatment of cultured cortical neurons by the proteasomal inhibitor lactacystin

A. Melendez, N. Cheung, A. Jenner, 2011, Journal of cellular physiology.

Identification of Nuclear Import Mechanisms for the Neuronal Cdk5 Activator*

R. Qi, N. Cheung, Yan Yu, 2006, Journal of Biological Chemistry.

Cellular mechanism of U18666A-mediated apoptosis in cultured murine cortical neurons: bridging Niemann-Pick disease type C and Alzheimer's disease.

N. Cheung, Chor Hui Vivien Koh, 2006, Cellular signalling.

Proteasome inhibition: an early or late event in nitric oxide-induced neuronal death?

P. Moore, A. Melendez, N. Cheung, 2008, Nitric oxide : biology and chemistry.

Kainate‐Induced Apoptosis in Cultured Murine Cerebellar Granule Cells Elevates Expression of the Cell Cycle Gene Cyclin D1

P. Beart, S. Giardina, N. Cheung, 1998, Journal of neurochemistry.

Development and survival of rat embryonic mesencephalic dopaminergic neurones in serum-free, antioxidant-rich primary cultures

P. Beart, N. Cheung, Y. M. Hickling, 1997, Neuroscience Letters.

PTEN is recruited to specific microdomains of the plasma membrane during lactacystin-induced neuronal apoptosis

B. Bay, Heung-Chin Cheng, N. Cheung, 2006, Neuroscience Letters.

Neuronal cell death caused by inhibition of intracellular cholesterol trafficking is caspase dependent and associated with activation of the mitochondrial apoptosis pathway

N. Cheung, Qiutian Li, Q. Hou, 2006, Journal of neurochemistry.

Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons

P. Moore, M. Whiteman, N. Cheung, 2007, Neuropharmacology.

Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro‐apoptotic transcriptional responses: a microarray analysis

Elaine H. J. Yew, E. Koay, B. Halliwell, 2005, Journal of neurochemistry.

Lactacystin-induced apoptosis of cultured mouse cortical neurons is associated with accumulation of PTEN in the detergent-resistant membrane fraction

B. Bay, H. Cheng, B. Halliwell, 2004, Cellular and Molecular Life Sciences.

Kainate‐induced apoptosis correlates with c‐Jun activation in cultured cerebellar granule cells

P. Beart, S. Giardina, N. Cheung, 1998, Journal of neuroscience research.

Common cellular and molecular mechanisms underlying Alzheimer's disease and type 2 diabetes: a knowledge-driven approach.

Peter Natesan Pushparaj, N. Cheung, K. Narasimhan, 2014, CNS & neurological disorders drug targets.

GSK3beta modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner.

Shufeng Zhou, W. Duan, N. Cheung, 2009, Cellular signalling.

Functional Studies with Substance P Analogues: Effects of N‐Terminal, C‐Terminal, and C‐Terminus‐Extended Analogues of Substance P on Nicotine‐Induced Secretion and Desensitization in Cultured Bovine Adrenal Chromaffin Cells

N. Cheung, M. Bienert, B. Livett, 1994, Journal of neurochemistry.

Structure-activity relationships of competitive NMDA receptor antagonists.

N. Cheung, R. Dutton, D. O'Callaghan, 1996, European journal of pharmacology.

Apoptosis Induced via AMPA‐Selective Glutamate Receptors in Cultured Murine Cortical Neurons

P. Beart, N. Cheung, J. Larm, 1997, Journal of neurochemistry.

Chromatographic Evidence for the Presence of Multiple Tachykinins in the Bovine Adrenal Medulla

N. Cheung, B. Livett, B. G. Livett, 1992, Journal of neurochemistry.

Glutaredoxin1 protects neuronal cells from copper-induced toxicity

K. Wolyniec, N. Cheung, Y. Yap, 2014, BioMetals.

Cholecystokinin-GABA interactions in rodent cortex: Analyses of cholecystokinin effects on K+- and l-glutamate-induced release of [3H]GABA from rat cortical slices and cultured mouse cortical neurones

P. Beart, N. Cheung, J. Larm, 1997, Neurochemistry International.

Investigations of non-NMDA receptor-induced toxicity in serum-free antioxidant-rich primary cultures of murine cerebellar granule cellsfn2 fn2 Abbreviations: AMPA, α amino-3-hydroxy-5-methyl-4-isoxazole propionate; CNQX, 6-Cyano-7-nitroquinoxaline-2,3-dione; div, days in vitro; GABA, γ-aminobu

P. Beart, N. Cheung, F. Carroll, 1998, Neurochemistry International.

(S)-5-fluorowillardiine-mediated neurotoxicity in cultured murine cortical neurones occurs via AMPA and kainate receptors.

P. Beart, N. Cheung, J. Larm, 1996, European journal of pharmacology.

Chlorinative stress: an under appreciated mediator of neurodegeneration?

Nam Sang Cheung, M. Whiteman, N. Cheung, 2007, Cellular signalling.

NMDA‐mediated activation of the NO/cGMP pathway: Caracteristics and regulation in cultured neocortical neurones

P. Beart, N. Cheung, F. Carroll, 1996, Journal of neuroscience research.

A global transcriptomic view of the multifaceted role of glutathione peroxidase-1 in cerebral ischemic-reperfusion injury.

A. Melendez, P. Crack, N. Cheung, 2011, Free radical biology & medicine.

Mice with a Homozygous Null Mutation for the Most Abundant Glutathione Peroxidase, Gpx1, Show Increased Susceptibility to the Oxidative Stress-inducing Agents Paraquat and Hydrogen Peroxide*

P Griffiths, I. Kola, M. Kelner, 1998, The Journal of Biological Chemistry.

Chronic exposure to U18666A induces apoptosis in cultured murine cortical neurons.

B. Bay, R. Qi, M. Whiteman, 2004, Biochemical and biophysical research communications.

Gene profiling reveals hydrogen sulphide recruits death signaling via the N‐methyl‐D‐aspartate receptor identifying commonalities with excitotoxicity

Nam Sang Cheung, M. Whiteman, P. Beart, 2011, Journal of cellular physiology.

Overexpression of Aβ is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model

C. Masters, R. Cherny, Qiao-Xin Li, 2006, Aging cell.

Sulfite-mediated oxidative stress in kidney cells.

B. Halliwell, M. Whiteman, N. Cheung, 2004, Kidney international.

The Last 10 Amino Acid Residues beyond the Hydrophobic Motif Are Critical for the Catalytic Competence and Function of Protein Kinase Cα*

Shufeng Zhou, N. Cheung, C. Verma, 2006, Journal of Biological Chemistry.

U18666A-mediated apoptosis in cultured murine cortical neurons: role of caspases, calpains and kinases.

B. Bay, W. Duan, R. Qi, 2006, Cellular signalling.

An Amyloid Peptide, βA4 25–35, Mimics the Function of Substance P on Modulation of Nicotine‐Evoked Secretion and Desensitization in Cultured Bovine Adrenal Chromaffin Cells

D. Small, N. Cheung, B. Livett, 1993, Journal of neurochemistry.

The Protein SET Binds the Neuronal Cdk5 Activator p35 nck5a and Modulates Cdk5/p35 nck5a Activity*

Rong Li, R. Qi, Jerry H. Wang, 2002, The Journal of Biological Chemistry.

Cyclothiazide and GYKI 52466 modulate AMPA receptor-mediated apoptosis in cortical neuronal cultures

P. Beart, S. Giardina, N. Cheung, 1999, Neuroscience Letters.

Micromolar l-glutamate induces extensive apoptosis in an apoptotic-necrotic continuum of insult-dependent, excitotoxic injury in cultured cortical neurones

P. Beart, S. Giardina, N. Cheung, 1998, Neuropharmacology.

Neuronal apoptosis mediated by inhibition of intracellular cholesterol transport: Microarray and proteomics analyses in cultured murine cortical neurons

R. Qi, A. Melendez, N. Cheung, 2007, Journal of cellular physiology.

Neurotoxin domoic acid produces cytotoxicity via kainate- and ampa-sensitive receptors in cultured cortical neurones

P. Beart, N. Cheung, J. Larm, 1997, Neurochemistry International.

Impaired neuronal insulin signaling precedes Aβ42 accumulation in female AβPPsw/PS1ΔE9 mice.

N. Cheung, B. Wong, Ze-ping Hu, 2012, Journal of Alzheimer's disease : JAD.

Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons

Colin L Masters, Barry Halliwell, Nam Sang Cheung, 2006, Journal of neurochemistry.

Oxidative stress: emerging mitochondrial and cellular themes and variations in neuronal injury.

P. Beart, N. Cheung, P. Nagley, 2010, Journal of Alzheimer's disease : JAD.

Gene profiling identifies commonalities in neuronal pathways in excitotoxicity: Evidence favouring cell cycle re-activation in concert with oxidative stress

P. Beart, N. Cheung, Minghui Jessica Chen, 2013, Neurochemistry International.

Multifaceted role of nitric oxide in an in vitro mouse neuronal injury model: transcriptomic profiling defines the temporal recruitment of death signalling cascades

P. Moore, M. Whiteman, G. Shui, 2011, Journal of cellular and molecular medicine.

Early induction of calpains in rotenone-mediated neuronal apoptosis

Wei Duan, Nam Sang Cheung, W. Duan, 2006, Neuroscience Letters.

Deciphering the mechanism of HNE-induced apoptosis in cultured murine cortical neurons: Transcriptional responses and cellular pathways

B. Halliwell, A. Melendez, N. Cheung, 2007, Neuropharmacology.

Gene expression profiling of rotenone-mediated cortical neuronal death: Evidence for inhibition of ubiquitin–proteasome system and autophagy-lysosomal pathway, and dysfunction of mitochondrial and calcium signaling

P. Beart, N. Cheung, Minghui Jessica Chen, 2013, Neurochemistry International.

Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor Fasudil reveals cytoskeletal and pro‐survival responses

V. Perreau, C. L. Lau, P. Beart, 2012, Journal of cellular physiology.

Microtubule Association of the Neuronal p35 Activator of Cdk5*

R. Qi, Z. Hou, Lisheng He, 2007, Journal of Biological Chemistry.

The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein

R. Qi, Lisheng He, N. Cheung, 2010, Cellular and Molecular Life Sciences.

Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS

A. Rembach, P. Beart, N. Cheung, 2004, Journal of neuroscience research.

The very C-terminus of protein kinase Cepsilon is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1.

Seng-Lai Tan, Shufeng Zhou, E. Chan, 2006, Cellular signalling.

Impaired insulin signaling in an animal model of Niemann-Pick Type C disease.

N. Cheung, B. Wong, C. Chua, 2012, Biochemical and biophysical research communications.

Hierarchical recruitment by AMPA but not staurosporine of pro‐apoptotic mitochondrial signaling in cultured cortical neurons: evidence for caspase‐dependent/independent cross‐talk

Baohong Chen, P. Beart, N. Cheung, 2007, Journal of neurochemistry.

Low‐affinity kainate receptor agonists induce insult‐dependent apoptosis and necrosis in cultured murine cortical neurons

P. Beart, N. Cheung, R. Moldrich, 2000, Journal of neuroscience research.

Identification of multiple tachykinins in bovine adrenal medulla using an improved chromatographic procedure

N. Cheung, B. G. Livett, S. Basile, 1993, Neuropeptides.

Excitotoxic injury profiles of low-affinity kainate receptor agonists in cortical neuronal cultures.

P. Beart, N. Cheung, R. Moldrich, 1999, European journal of pharmacology.

Pituitary adenylate cyclase‐activating polypeptide induces translocation of its G‐protein‐coupled receptor into caveolin‐enriched membrane microdomains, leading to enhanced cyclic AMP generation and neurite outgrowth in PC12 cells

W. Duan, N. Cheung, Qiutian Li, 2007, Journal of neurochemistry.

Comparative Microarray Analysis Identifies Commonalities in Neuronal Injury: Evidence for Oxidative Stress, Dysfunction of Calcium Signalling, and Inhibition of Autophagy–Lysosomal Pathway

P. Beart, N. Cheung, Y. Yap, 2016, Neurochemical Research.

Human Bcl‐2 Protects Against AMPA Receptor‐Mediated Apoptosis

O. Bernard, P. Beart, N. Cheung, 2000, Journal of neurochemistry.

Annexin A3 is associated with cell death in lactacystin-mediated neuronal injury

E. Koay, A. Lee, N. Cheung, 2010, Neuroscience Letters.

Transcriptional insights on the regenerative mechanics of axotomized neurons in vitro

J. Vickers, R. Qi, N. Cheung, 2012, Journal of cellular and molecular medicine.

Antioxidants: promising neuroprotection against cardiotoxin-4b-induced cell death which triggers oxidative stress with early calpain activation.

A. Armugam, K. Jeyaseelan, N. Cheung, 2008, Toxicon : official journal of the International Society on Toxinology.

Erratum: Peroxynitrite mediates calcium-dependent mitochondrial dysfunction and cell death via activation of calpains (FASEB Journal (2004) 18 (1395-1397) DOI: 10.1096/fj.03-1096fje)

Dean P. Jones, J. Schantz, B. Halliwell, 2012 .

Excitotoxic profile of LY339434, a GluR5 agonist, in cultured murine cortical neurons

P. Beart, N. Cheung, C. Pedregal, 2000, Brain Research.

Gene profiling reveals hydrogen sulphide recruits death signaling via the N‐methyl‐D‐aspartate receptor identifying commonalities with excitotoxicity

M. Whiteman, P. Beart, A. Melendez, 2011, Journal of cellular physiology.

Gene profiling identifies commonalities in neuronal pathways in excitotoxicity: Evidence favouring cell cycle re-activation in concert with oxidative stress

P. Beart, N. Cheung, Minghui Jessica Chen, 2013, Neurochemistry International.