K. Hong

发表

Assembly of nucleic acid-lipid nanoparticles from aqueous-organic monophases.

J. Marks, D. Drummond, M. Hayes, 2006, Biochimica et biophysica acta.

Cationic Liposomes Coated with Polyethylene Glycol As Carriers for Oligonucleotides*

John W. Park, D. Papahadjopoulos, M. Woodle, 1998, The Journal of Biological Chemistry.

Immunoliposomes for cancer treatment.

John W. Park, C. Benz, D. Kirpotin, 1997, Advances in pharmacology.

Interaction of cationic liposomes with cells of electrically active neuronal networks in culture

G. Gross, H. Azzazy, K. Hong, 1995, Brain Research.

Stabilization of cationic liposome‐plasmid DNA complexes by polyamines and poly(ethylene glycol)‐phospholipid conjugates for efficient in vivo gene delivery

D. Papahadjopoulos, K. Hong, Weiwen Zheng, 1997, FEBS letters.

Endocytosis of liposomes and intracellular fate of encapsulated molecules: Encounter with a low pH compartment after internalization in coated vesicles

D. Friend, D. Papahadjopoulos, K. Hong, 1983, Cell.

Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models.

U. Nielsen, C. Benz, John W. Park, 2006, Cancer research.

Thermosensitive liposomes: extravasation and release of contents in tumor microvascular networks.

M. Dewhirst, D. Papahadjopoulos, K. Hong, 1996, International journal of radiation oncology, biology, physics.

Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo.

C. Mamot, John W. Park, D. Drummond, 2005, Cancer research.

Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors.

D. Papahadjopoulos, D. Drummond, D. Kirpotin, 1999, Pharmacological reviews.

Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery.

Ulrik B Nielsen, U. Nielsen, J. Baselga, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Gadolinium-loaded liposomes allow for real-time magnetic resonance imaging of convection-enhanced delivery in the primate brain

Ryuta Saito, Mitchel S. Berger, Krystof S. Bankiewicz, 2005, Experimental Neurology.

Endocytosis of liposomes by macrophages: binding, acidification and leakage of liposomes monitored by a new fluorescence assay.

D. Papahadjopoulos, K. Hong, D. Daleke, 1990, Biochimica et biophysica acta.

Extensive Distribution of Liposomes in Rodent Brains and Brain Tumors Following Convection-Enhanced Delivery

M. Berger, C. Mamot, John W. Park, 2004, Journal of Neuro-Oncology.

In vivo Multiple Anticancer Drugs Immunoliposomes Significantly Enhance the Efficacy of Targeted − Epidermal Growth Factor Receptor

C. Mamot, John W. Park, D. Drummond, 2005 .

Epidermal Growth Factor Receptor (EGFR)-targeted Immunoliposomes Mediate Specific and Efficient Drug Delivery to EGFR- and EGFRvIII-overexpressing Tumor Cells1

C. Mamot, John W. Park, J. Marks, 2003 .

Epidermal Growth Factor Receptor ( EGFR )-targeted Immunoliposomes Mediate Specific and Efficient Drug Delivery to EGFR-and EGFRvIII-overexpressing Tumor Cells 1

C. Mamot, John W. Park, J. Marks, 2003 .

In vitro studies on sterically stabilized liposomes (SL) as enzyme carriers in organophosphorus (OP) antagonism.

J. L. Way, J. Defrank, D. Papahadjopoulos, 2000, Drug delivery.

Physicochemical characterization of large unilamellar phospholipid vesicles prepared by reverse-phase evaporation.

D. Friend, T. James, D. Papahadjopoulos, 1983, Biochimica et biophysica acta.

Development of a highly stable and targetable nanoliposomal formulation of topotecan.

Ceirin M. Connolly-Ingram, C. Benz, B. Hann, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Conjugation of apolipoprotein B with liposomes and targeting to cells in culture.

D. Papahadjopoulos, K. Hong, B. Lundberg, 1993, Biochimica et biophysica acta.

Interactions of annexins with membrane phospholipids.

D. Papahadjopoulos, K. Hong, P. Meers, 1991, Biochemistry.

Annexin-Phospholipid Interactions in Membrane Fusion

K. Hong, P. Meers, D. Papaphadjopoulos, 1991 .

Efficiency of Cytoplasmic Delivery by pH-Sensitive Liposomes to Cells in Culture

F. Szoka, J. Dijkstra, K. Hong, 1990, Pharmaceutical Research.

Free fatty acid enhancement of cation-induced fusion of liposomes: synergism with synexin and other promoters of vesicle aggregation.

D. Papahadjopoulos, K. Hong, P. Meers, 1988, Biochemistry.

Synexin enhances the aggregation rate but not the fusion rate of liposomes.

D. Papahadjopoulos, S. Nir, D. Alford, 1988, Biochemistry.

Calcium-Induced Membrane Fusion: From Liposomes to Cellular Membranes

J. Ernst, D. Papahadjopoulos, N. Düzgüneş, 1988 .

Fusion of Phospholipid Vesicles Induced by Divalent Cations and Protons

D. Papahadjopoulos, S. Nir, N. Düzgüneş, 1987 .

Protein Modulation of Liposome Fusion

D. Papahadjopoulos, N. Düzgüneş, K. Hong, 1987 .

Polyamines as modulators of membrane fusion: aggregation and fusion of liposomes.

D. Papahadjopoulos, N. Düzgüneş, F. Schuber, 1983, Biochemistry.

Light microscopic localization of silver-enhanced liposome-entrapped colloidal gold in mouse tissues.

D. Friend, D. Papahadjopoulos, K. Hong, 1991, Biochimica et biophysica acta.

Cationic Liposome-DNA Complexes: Polymorphism versus Transfection Activity

D. Papahadjopoulos, K. Hong, W. Zheng, 2000, Microscopy and Microanalysis.

Ultrastructural Morphology of Cationic Liposome/Dna Complexes for Gene Therapy: Correlation to Transfection Activity

D. Papahadjopoulos, K. Hong, B. Sternberg, 1999 .

Ultrastructural characterization of cationic liposome-DNA complexes showing enhanced stability in serum and high transfection activity in vivo.

D. Papahadjopoulos, K. Hong, B. Sternberg, 1998, Biochimica et biophysica acta.

by dendritic cells initiates CD8+ T-cell responses in vivo Presentation of proteins encapsulated in sterically stabilized liposomes

R. Steinman, L. Stamatatos, K. Hong, 2013 .

Presentation of proteins encapsulated in sterically stabilized liposomes by dendritic cells initiates CD8(+) T-cell responses in vivo.

R. Steinman, L. Stamatatos, K. Hong, 2000, Blood.

Endocytosis and intracellular fate of liposomes using pyranine as a probe.

D. Papahadjopoulos, K. Hong, R. Straubinger, 1990, Biochemistry.

Role of synexin in membrane fusion. Enhancement of calcium-dependent fusion of phospholipid vesicles.

D. Papahadjopoulos, N. Düzgüneş, K. Hong, 1981, The Journal of biological chemistry.

Increased liposome extravasation in selected tissues: effect of substance P.

J. Rosenecker, J. Nadel, D. Papahadjopoulos, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Endocytosis of Liposomes and Intracellular Fate of Encapsulated Molecules: Strategies for Enhanced Cytoplasmic Delivery

D. Friend, D. Papahadjopoulos, N. Düzgüneş, 1984 .

Liposomes containing colloidal gold are a useful probe of liposome-cell interactions.

D. Friend, D. Papahadjopoulos, C. Glabe, 1983, Biochimica et biophysica acta.

Steric Stabilization of Cationic Liposome-DNA Complexes: Influence on Morphology and Transfection Activity

D. Papahadjopoulos, K. Hong, B. Sternberg, 1998 .

Spermine as a modulator of membrane fusion: interactions with acidic phospholipids.

D. Papahadjopoulos, J. Bentz, K. Hong, 1986, Biochemistry.

Role of ligand in antibody-directed endocytosis of liposomes by human T-leukemia cells.

K. Matthay, D. Papahadjopoulos, K. Hong, 1989, Cancer research.

Improved Pharmacokinetics and Efficacy of a Highly Stable Nanoliposomal Vinorelbine

John W. Park, D. Drummond, C. Noble, 2009, Journal of Pharmacology and Experimental Therapeutics.

Gd-labeled liposomes for monitoring liposome-encapsulated chemotherapy: quantification of regional uptake in tumor and effect on drug delivery.

F. Berger, M. Wendland, K. Stevens, 2002, Academic radiology.

Membrane contact, fusion, and hexagonal (HII) transitions in phosphatidylethanolamine liposomes.

D. Papahadjopoulos, T. Allen, K. Hong, 1986, Biochemistry.

Fluorometric detection of the bilayer-to-hexagonal phase transition in liposomes.

D. Papahadjopoulos, T. Allen, K. Hong, 1988, Biochemistry.

THE INCREASED EFFICACY AND DECREASED NEPHROTOXICITY OF A CYCLOSPORINE LIPOSOME1,2

L. Ferrell, J. Roberts, D. Papahadjopoulos, 1994, Transplantation.

Anti‐HER2 Immunoliposomes for Targeted Drug Delivery

C. Benz, D. Papahadjopoulos, R. Shalaby, 1999, Annals of the New York Academy of Sciences.

Polyamines. Biological modulators of membrane fusion.

D. Papahadjopoulos, F. Schuber, K. Hong, 1983, Biochimica et biophysica acta.

Mechanism of protein-induced membrane fusion: fusion of phospholipid vesicles by clathrin associated with its membrane binding and conformational change.

D. Papahadjopoulos, N. Düzgüneş, K. Hong, 1989, Biochemistry.

Interaction of clathrin with liposomes: pH‐dependent fusion of phospholipid membranes induced by clathrin

D. Papahadjopoulos, K. Hong, T. Yoshimura, 1985, FEBS letters.

Modulation of membrane fusion by calcium-binding proteins.

D. Papahadjopoulos, N. Düzgüneş, K. Hong, 1982, Biophysical journal.

Fusion of liposomes induced by a cationic protein from the acrosome granule of abalone spermatozoa.

V. Vacquier, K. Hong, 1986, Biochemistry.

Sterically Stabilized Immunoliposomes: Formulations for Delivery of Drugs and Genes to Tumor Cells in Vivo

C. Benz, John W. Park, D. Papahadjopoulos, 1998 .

Formulation and evaluation of multilamellar vesicles ropivacaine in pain management

K. Hong, Hao-Wen Kao, Yi-Yu Lin, 2019, International journal of nanomedicine.

Simple and efficient liposomal encapsulation of topotecan by ammonium sulfate gradient: stability, pharmacokinetic and therapeutic evaluation

F. Chang, K. Hong, Y. Tseng, 2002, Anti-cancer drugs.

Liposome-based approaches to overcome anticancer drug resistance.

C. Mamot, John W. Park, D. Drummond, 2003, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy.

John W. Park, D. Drummond, C. Noble, 2006, Cancer research.

Anti-HER2 immunoliposomes for targeted therapy of human tumors.

C. Benz, D. Papahadjopoulos, D. Kirpotin, 1997, Cancer letters.

Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma.

M. Dewhirst, T. Secomb, D. Papahadjopoulos, 1996, Cancer research.

THE NONCOVALENT COUPLING OF RHODOPSIN and PHOSPHATIDYLCHOLINES *

W. Hubbell, K. Hong, Yong‐Shiau Chen, 1973, Annals of the New York Academy of Sciences.

Genospheres: self-assembling nucleic acid-lipid nanoparticles suitable for targeted gene delivery

C. Benz, John W. Park, J. Marks, 2006, Gene Therapy.

Liposome-based therapy of human ovarian cancer: parameters determining potency of negatively charged and antibody-targeted liposomes.

D. Papahadjopoulos, R. Debs, K. Hong, 1988, Cancer research.

Thermosensitive Sterically Stabilized Liposomes: Formulation and in Vitro Studies on Mechanism of Doxorubicin Release by Bovine Serum and Human Plasma

D. Papahadjopoulos, K. Hong, Shiying Huang, 1995, Pharmaceutical Research.

Development of ligand-targeted liposomes for cancer therapy

C. Benz, C. Mamot, John W. Park, 2004, Expert opinion on therapeutic targets.

Liposome targeting to tumors using vitamin and growth factor receptors.

C. Benz, D. Drummond, D. Kirpotin, 2000, Vitamins and hormones.

Recognition of liposomes by cells: in vitro binding and endocytosis mediated by specific lipid headgroups and surface charge density.

D. Papahadjopoulos, K. Hong, K. D. Lee, 1992, Biochimica et biophysica acta.

Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells.

Udo Greiser, C. Mamot, John W. Park, 2003, Cancer research.

Preclinical Manufacture of Anti‐HER2 Liposome‐Inserting, scFv‐PEG‐Lipid Conjugate. 2. Conjugate Micelle Identity, Purity, Stability, and Potency Analysis

John W. Park, J. Marks, D. Drummond, 2008, Biotechnology progress.

Preclinical Manufacture of an Anti‐HER2 scFv‐PEG‐DSPE, Liposome‐Inserting Conjugate. 1. Gram‐Scale Production and Purification

Jianwei Zhu, Jianwei Zhu, John W. Park, 2008, Biotechnology progress.

Therapeutic efficacy of anti-ErbB2 immunoliposomes targeted by a phage antibody selected for cellular endocytosis.

Ulrik B Nielsen, U. Nielsen, C. Benz, 2002, Biochimica et biophysica acta.

Sterically stabilized anti-HER2 immunoliposomes: design and targeting to human breast cancer cells in vitro.

John W. Park, C. Benz, P. Carter, 1997, Biochemistry.

Microscopic localization of sterically stabilized liposomes in colon carcinoma-bearing mice.

D. Friend, D. Papahadjopoulos, K. Hong, 1992, Cancer research.

Liposomal Drug Delivery Systems for Cancer Therapy

C. Benz, John W. Park, D. Drummond, 2004 .

Anti-HER 2 Immunoliposomes : Enhanced Efficacy Attributable to Targeted Delivery 1

U. Nielsen, J. Baselga, C. Benz, 2002 .

Tumor targeting using anti-her2 immunoliposomes.

U. Nielsen, C. Benz, John W. Park, 2001, Journal of controlled release : official journal of the Controlled Release Society.

CHAPTER 4.7 – Targeting of sterically stabilized liposomes to cancers overexpressing HER2/neu proto-oncogene

C. Benz, John W. Park, D. Papahadjopoulos, 1998 .

Targeting of Drugs to Solid Tumors Using Anti-Her2 Immunoliposomes

C. Benz, John W. Park, D. Papahadjopoulos, 1998 .

Targeting of Liposomes to Solid Tumors: The Case of Sterically Stabilized Anti-Her2 Immunoliposomes

C. Benz, John W. Park, D. Papahadjopoulos, 1997 .

Long circulating liposomes encapsulating organophosphorus acid anhydrolase in diisopropylfluorophosphate antagonism.

J. L. Way, J. Defrank, D. Papahadjopoulos, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

Liposomes with detachable polymer coating: destabilization and fusion of dioleoylphosphatidylethanolamine vesicles triggered by cleavage of surface‐grafted poly(ethylene glycol)

Samuel Zalipsky, D. Papahadjopoulos, D. Kirpotin, 1996, FEBS letters.

Emerging antibody-based HER2 (ErbB-2/neu) therapeutics.

C. Benz, D. Kirpotin, K. Hong, 2000, Breast disease.

Antagonism of paraoxon intoxication by recombinant phosphotriesterase encapsulated within sterically stabilized liposomes.

J. L. Way, G. Omburo, D. Papahadjopoulos, 1999, Toxicology and applied pharmacology.

Liposomes and hyperthermia in mice: increased tumor uptake and therapeutic efficacy of doxorubicin in sterically stabilized liposomes.

P. Stauffer, T. Phillips, D. Papahadjopoulos, 1994, Cancer research.

Cationic liposome mediated transgene expression in the guinea pig cochlea

A. Lalwani, Jay J. Han, A. Mhatre, 1999, Hearing Research.

RETENTION OF AQUEOUS CONTENTS DURING DIVALENT CATION-INDUCED FUSION OF PHOSPHOLIPID-VESICLES

D. Papahadjopoulos, N. Düzgüneş, D. Hoekstra, 1983 .

Microvascular studies on the origins of perfusion-limited hypoxia.

M. Dewhirst, T. Secomb, D. Papahadjopoulos, 1996, The British journal of cancer. Supplement.

Synexin facilitates fusion of specific phospholipid membranes at divalent cation concentrations found intracellularly.

D. Papahadjopoulos, N. Düzgüneş, K. Hong, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Expression of ΔF508 CFTR in normal mouse lung after site-specific modification of CFTR sequences by SFHR

B. Dallapiccola, G. Novelli, D. Papahadjopoulos, 2001, Gene Therapy.

Increased target specificity of anti-HER2 genospheres by modification of surface charge and degree of PEGylation.

C. Benz, J. Cohen, J. Marks, 2006, Molecular pharmaceutics.

Comparing therapeutic and prophylactic protection against the lethal effect of paraoxon.

J. L. Way, D. Papahadjopoulos, K. Hong, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

Decreased progesterone binding and attenuated progesterone action in cultured human breast carcinoma cells treated with epidermal growth factor.

W. Blattner, J. Nadeau, C. Pui, 1988, Cancer research.

Development of novel liposomal and receptor tyrosine kinase-targeted immunoliposomal vinorelbine formulations with improved drug retention

C. Mamot, John W. Park, J. Marks, 2005 .

Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells.

C. Mamot, John W. Park, J. Marks, 2003, Cancer research.

Liposomal Drug Delivery Systems for Cancer Therapy

C. Benz, John W. Park, D. Drummond, 2004 .