W. Murphy

P. Parham, Jeffrey S. Miller, W. Murphy, 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic HSCT: Graft-versus-Tumor/Leukemia Reaction.

J. Ritz, M. V. D. van den Brink, A. Barrett, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Antigen-specific versus Antigen-nonspecific Immunotherapeutic Approaches for Human Melanoma: The Need for Integration for Optimal Efficacy?

W. Murphy, J. Tietze, H. Hsiao, 2011, International reviews of immunology.

Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro.

D. Taub, D. Longo, W. Murphy, 1996, Journal of immunology.

Enhanced targeting of stem-like solid tumor cells with radiation and natural killer cells

W. Murphy, Mingyi Chen, R. Canter, 2015, Oncoimmunology.

Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation.

D. Taub, D. Longo, F. Ruscetti, 1998, The Journal of clinical investigation.

Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses.

S. Furlan, D. Munn, J. Serody, 2020, Blood.

Mechanical Disruption of Tumors by Iron Particles and Magnetic Field Application Results in Increased Anti-Tumor Immune Responses

A. Fuchs, W. Murphy, M. Fung, 2012, PloS one.

Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice.

D. Taub, D. Longo, W. Murphy, 1996, Blood.

Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

L. Ferrucci, J. Weiss, D. Taub, 2013, The Journal of experimental medicine.

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

L. Ferrucci, D. Taub, D. Longo, 2014, The Journal of experimental medicine.

Inhibition of Inositol kinase B controls acute and chronic graft-versus-host disease.

J. Ritz, D. Munn, J. Serody, 2019, Blood.

Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens.

Ji Ming Wang, L. Kwak, W. Murphy, 2000, International immunology.

Therapeutic Efficacy of Fresh, Allogeneic Mesenchymal Stem Cells for Severe Refractory Feline Chronic Gingivostomatitis

N. Vapniarsky, B. Arzi, F. Verstraete, 2017, Stem cells translational medicine.

Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease.

W. Murphy, K. Sun, L. Welniak, 2008, Expert opinion on pharmacotherapy.

Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease

W. Murphy, K. Sun, L. Welniak, 2008, Expert opinion on pharmacotherapy.

Synthase Gene Induction of the Inducible Nitric Oxide in α Macrophages : Pivotal Role of Stat 1 in Mouse α Transcription Factor Stat 1 Lipopolysaccharide-Induced Activation of Mediates the βα Autocrine / Paracrine IFN -

Jianjun Gao, S. Vogel, S. Russell, 1998 .

Autocrine/Paracrine IFN-αβ Mediates the Lipopolysaccharide-Induced Activation of Transcription Factor Stat1α in Mouse Macrophages: Pivotal Role of Stat1α in Induction of the Inducible Nitric Oxide Synthase Gene

Jianjun Gao, S. Vogel, S. Russell, 1998, The Journal of Immunology.

Immunotherapy following hematopoietic stem cell transplantation: potential for synergistic effects.

W. Murphy, M. Bouchlaka, D. Redelman, 2010, Immunotherapy.

A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion.

D. Longo, R. Badolato, M. Anver, 1995, Journal of immunology.

Growth Inhibition and Apoptosis of RI Human B lymphoma Cells by Vitamin E Succinate and Retinoic Acid : Role for Transforming Growth Factor 1

D. Longo, F. Ruscetti, W. Murphy, 2005 .

Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor beta.

D. Longo, F. Ruscetti, W. Murphy, 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Metastatic immune infiltrates correlate with those of the primary tumour in canine osteosarcoma.

K. Woolard, R. Rebhun, R. Laufer-Amorim, 2019, Veterinary and comparative oncology.

Association of macrophage and lymphocyte infiltration with outcome in canine osteosarcoma

K. Woolard, C. Rodriguez, R. Rebhun, 2018, Veterinary and comparative oncology.

Therapeutic Effects of a NEDD8-Activating Enzyme Inhibitor, Pevonedistat, on Sclerodermatous Graft-versus-Host Disease in Mice.

W. Murphy, Mingyi Chen, Lam T. Khuat, 2017, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

The path(way) less traveled.

W. Murphy, M. Abedi, 2013, Blood.

Stereotactic Ablative Radiation Therapy Induces Systemic Differences in Peripheral Blood Immunophenotype Dependent on Irradiated Site.

K. Kelly, R. Valicenti, S. Stewart, 2018, International journal of radiation oncology, biology, physics.

Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation

Robin R. Shields-Cutler, D. Longo, D. Knights, 2020, Science Translational Medicine.

Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo model for genetically transferred chemoprotection.

D. Longo, J. Keller, P. Schwarzenberger, 1996, Blood.

Cellular and Molecular Considerations for the Treatment of Murine Renal Cancer

D. Longo, J. Franco, D. Kelvin, 1995 .

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts

Amanda R. Campbell, F. Lund-Johansen, Yair Benita, 2016, Journal for ImmunoTherapy of Cancer.

Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD

G. Hill, W. Murphy, B. Blazar, 2020, Nature Reviews Clinical Oncology.

The complicated effects of obesity on cancer and immunotherapy.

W. Murphy, A. Monjazeb, Ziming Wang, 2019, Immunotherapy.

CTL-Promoting Effects of CD40 Stimulation Outweigh B Cell-Stimulatory Effects Resulting in B Cell Elimination and Disease Improvement in a Murine Model of Lupus1

M. Haas, W. Murphy, L. Welniak, 2008, The Journal of Immunology.

Improvement in a Murine Model of Lupus Resulting in B Cell Elimination and Disease Outweigh B Cell-Stimulatory Effects CTL-Promoting Effects of CD 40 Stimulation

M. Haas, W. Murphy, L. Welniak, 2008 .

Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells.

W. Murphy, B. Blazar, A. Hanash, 2006, Proceedings of the National Academy of Sciences of the United States of America.

NK cells and CD8 T cells in cancer immunotherapy: Similar functions by different mechanisms

W. Murphy, I. Barão, C. Dunai, 2021, Successes and Challenges of NK Immunotherapy.

Effects of cancer immunotherapy regimens on primary vs. secondary immune responses and the potential impact on long-term antitumor responses.

W. Murphy, K. Alderson, Kory L. Alderson, 2009, Advances in experimental medicine and biology.

InhibitionCell-Mediated Killing by Proteasome Sensitization of Tumor Cells to NK

T. Sayers, W. Murphy, D. Tamang, 2007 .

In Vivo Hydrodynamic Delivery of cDNA Encoding IL-2: Rapid, Sustained Redistribution, Activation of Mouse NK Cells, and Therapeutic Potential in the Absence of NKT Cells1

J. Ortaldo, R. Wiltrout, W. Murphy, 2005, The Journal of Immunology.

Absence of NKT Cells Cells, and Therapeutic Potential in the Redistribution, Activation of Mouse NK Encoding IL-2: Rapid, Sustained In Vivo Hydrodynamic Delivery of cDNA

J. Ortaldo, R. Wiltrout, W. Murphy, 2005 .

CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery.

A. Borowsky, W. Murphy, J. Foiret, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy

J. Weiss, C. Harris, D. Wink, 2010, The Journal of experimental medicine.

Analysis of tumor-infiltrating NK and T cells highlights IL-15 stimulation and TIGIT blockade as a combination immunotherapy strategy for soft tissue sarcomas

S. Thorpe, R. Rebhun, W. Murphy, 2020, Journal for ImmunoTherapy of Cancer.

Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer

K. Kelly, D. Proia, W. Murphy, 2015, Oncoimmunology.

Thymic emigrants isolated by a new method possess unique phenotypic and functional properties.

K. Muegge, S. Durum, W. Murphy, 2001, Blood.

Stimulating Innate Immunity to Enhance Radiation Therapy-Induced Tumor Control.

W. Murphy, A. Monjazeb, M. Crittenden, 2017, International journal of radiation oncology, biology, physics.

NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade.

J. Ortaldo, W. Murphy, B. Blazar, 2003, Blood.

Retinoic acid signaling acts as a rheostat to balance Treg function

S. Furlan, D. Munn, H. Chi, 2022, Cellular & Molecular Immunology.

Natural killer cell immunotherapy to target stem-like tumor cells

W. Murphy, R. Canter, S. Grossenbacher, 2016, Journal of Immunotherapy for Cancer.

Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells

K. Lam, Aijun Wang, R. Weichselbaum, 2020, Nature Communications.

Increased Antitumor Effects Using IL-2 with Anti–TGF-β Reveals Competition between Mouse NK and CD8 T Cells

W. Murphy, Mingyi Chen, G. Sckisel, 2014, The Journal of Immunology.

Utilization of mouse models to decipher natural killer cell biology and potential clinical applications.

W. Murphy, Can M Sungur, Can M. Sungur, 2013, Hematology. American Society of Hematology. Education Program.

Murine natural killer cell licensing and regulation by T regulatory cells in viral responses

D. Longo, W. Murphy, Mingyi Chen, 2013, Proceedings of the National Academy of Sciences.

Murine NK-cell licensing is reflective of donor MHC-I following allogeneic hematopoietic stem cell transplantation in murine cytomegalovirus responses.

W. Murphy, Can M Sungur, C. Pomeroy, 2013, Blood.

The Surprisingly Positive Association Between Obesity and Cancer Immunotherapy Efficacy.

D. Longo, W. Murphy, 2019, JAMA.

Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes

R. Badolato, Ji Ming Wang, L. Bausserman, 1994, The Journal of experimental medicine.

Donor HSCs with a preexisting ASXL1-mutation led to the development of FLT3-ITD positive AML in the donor and FLT3-ITD negative AML in the recipient after unrelated transplant

Mingyi Chen, W. Murphy, L. Huo, 2018, Bone Marrow Transplantation.

Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial

J. Modiano, Jesus I. Luna, W. Murphy, 2017, Journal of Immunotherapy for Cancer.

Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib.

J. Serody, T. Sayers, W. Murphy, 2004, Proceedings of the National Academy of Sciences of the United States of America.

The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.

P. Elliott, T. Sayers, A. Brooks, 2003, Blood.

Transcriptome Analysis of Tumor-Infiltrating Lymphocytes Identifies NK Cell Gene Signatures Associated With Lymphocyte Infiltration and Survival in Soft Tissue Sarcomas

R. Rebhun, W. Murphy, Kevin M. Stoffel, 2022, Frontiers in Immunology.

Generation of Artificial Proteoglycans Containing Glycosaminoglycan-modified CD44

D. Taub, A. Aruffo, W. Murphy, 1999, The Journal of Biological Chemistry.

Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease.

J. Qi, J. Bradner, A. Melnick, 2019, Blood.

Attenuated Age-Impact on Systemic Inflammatory Markers in the Presence of a Metabolic Burden

L. Beckett, Wei Zhang, W. Murphy, 2015, PloS one.

The neutrophil granule protein cathepsin G activates murine T lymphocytes and upregulates antigen-specific IG production in mice.

W. Murphy, K. Tani, J. Wang, 2001, Biochemical and biophysical research communications.

Advantages and clinical applications of natural killer cells in cancer immunotherapy

W. Murphy, E. Ames, Erik Ames, 2013, Cancer Immunology, Immunotherapy.

Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated anti-tumor responses

R. Bruce, W. Murphy, E. Ames, 2009 .

Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses.

W. Murphy, B. Blazar, P. Taylor, 2008, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Positive and negative regulation of Natural Killer cells: therapeutic implications.

W. Murphy, W. Hallett, 2006, Seminars in cancer biology.

Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts.

D. Longo, T. Sayers, T. Back, 1993, The Journal of clinical investigation.

Inflammatory joint diseases: the province of rheumatologists

W. Murphy, 2001 .

The Immunotherapy and Immunosuppressive Signaling in Therapy-Resistant Prostate Cancer

W. Murphy, C. Evans, Joy C. Yang, 2022, Biomedicines.

Novel tumor necrosis factor‐knockout mice that lack Peyer's patches

L. Tessarollo, M. Drutskaya, S. Nedospasov, 2005, European journal of immunology.

PD-1 Blockade Reverses Obesity-Mediated T Cell Priming Impairment

W. Murphy, B. Blazar, Kevin M. Stoffel, 2020, Frontiers in Immunology.

Moving forward to address key unanswered questions on targeting PD-1/PD-L1 in cancer: limitations in preclinical models and the need to incorporate human modifying factors

W. Murphy, Catherine T. Le, 2019, Journal of Immunotherapy for Cancer.

Human‐mouse lymphoid chimeras: host‐vs.‐graft and graft‐vs.‐host reactions

D. Longo, M. Baseler, M. Anver, 1992, European journal of immunology.

Engraftment and activity of anti-CD3-activated human peripheral blood lymphocytes transferred into mice with severe combined immune deficiency.

D. Longo, T. Sayers, T. Back, 1993, Journal of immunology.

T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo.

D. Taub, D. Longo, M. Anver, 1996, The Journal of clinical investigation.

GVHD-associated, inflammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells.

D. Munn, J. Tolar, J. Serody, 2015, Blood.

IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function.

M. Roncarolo, S. Narula, W. Murphy, 2003, Blood.

In Vivo Models for the Study of Graft-vs-Host Disease and Graft-vs-Tumor Effects

W. Murphy, K. Sun, L. Welniak, 2003 .

CD40 stimulation promotes human secondary immunoglobulin responses in HuPBL-SCID chimeras.

D. Taub, D. Longo, W. Murphy, 1999, Clinical immunology.

Effects of CD40 stimulation in the prevention of human EBV-lymphomagenesis.

D. Taub, D. Longo, F. Ruscetti, 1997, Leukemia & lymphoma.

Antitumor effects of nonconjugated murine Lym-2 and human-mouse chimeric CLL-1 monoclonal antibodies against various human lymphoma cell lines in vitro and in vivo.

D. Longo, L. Khawli, M. Beckwith, 1997, Blood.

Antibodies to CD40 prevent Epstein-Barr virus-mediated human B-cell lymphomagenesis in severe combined immune deficient mice given human peripheral blood lymphocytes.

D. Taub, M. Beckwith, W. Murphy, 1995, Blood.

Human RANTES induces the migration of human T lymphocytes into the peripheral tissues of mice with severe combined immune deficiency

W. Murphy, Dennis D. Taubu, Miriam Anveru, 1994, European journal of immunology.

Inhibition of human B-cell lymphoma growth by CD40 stimulation.

D. Longo, I. Tsarfaty, M. Beckwith, 1994, Blood.

Recombinant human growth hormone promotes human lymphocyte engraftment in immunodeficient mice and results in an increased incidence of human Epstein Barr virus-induced B-cell lymphoma

D. Longo, M. Anver, S. Durum, 1992, Brain, Behavior, and Immunity.

The huPBL-SCID mouse as a means to examine human immune function in vivo.

D. Taub, D. Longo, W. Murphy, 1996, Seminars in immunology.

Hematopoietic progenitor cell regulation by CD4+CD25+ T cells.

W. Murphy, B. Blazar, R. Levy, 2010, Blood.

Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD)

W. Murphy, B. Blazar, 2005, Philosophical Transactions of the Royal Society B: Biological Sciences.

Acute rejection of murine bone marrow allografts by natural killer cells and T cells. Differences in kinetics and target antigens recognized

W. Murphy, M. Bennett, V. Kumar, 1987, The Journal of experimental medicine.

CHAPTER 5 – Growth hormone

W. Murphy, L. Welniak, 2003 .

Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice.

D. Taub, D. Longo, R. Wiltrout, 1998, The Journal of clinical investigation.

“Unlicensed” Natural Killer cells dominate the response to cytomegalovirus infection

L. Lanier, W. Murphy, M. T. Orr, 2010, Nature Immunology.

Ly‐49 receptor expression and functional analysis in multiple mouse strains

J. Ortaldo, W. Murphy, R. Winkler-Pickett, 1999, Journal of leukocyte biology.

Licensing delineates helper and effector NK cell subsets during viral infection.

D. Longo, W. Murphy, N. Baumgarth, 2017, JCI insight.

Positive and negative regulation by NK cells in cancer.

W. Murphy, Can M Sungur, Can M. Sungur, 2014, Critical reviews in oncogenesis.

Transcriptional basis for hyporesponsiveness of the human inducible nitric oxide synthase gene to lipopolysaccharide/interferon‐γ

K. Edwards, S. Russell, W. Murphy, 1996, Journal of leukocyte biology.

Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion

Aijun Wang, H. Kung, S. Xia, 2022, Nature Communications.

GVHD-associated , in fl ammasome-mediated loss of function in adoptively transferred myeloid-derived suppressor cells

D. Munn, J. Tolar, J. Serody, 2015 .

Late administration of murine CTLA-4 blockade prolongs CD8-mediated anti-tumor effects following stimulatory cancer immunotherapy

W. Murphy, B. Blazar, Mingyi Chen, 2015, Cancer Immunology, Immunotherapy.

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration.

E. Dmitrovsky, D. Munn, J. Tolar, 2013, Blood.

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality.

D. Munn, J. Serody, J. Allison, 2019, JCI insight.

CD16 Cross-Linking Blocks Rearrangement of the TCRβ Locus and Development of αβ T Cells and Induces Development of NK Cells from Thymic Progenitors

K. Muegge, S. Durum, W. Murphy, 1998, The Journal of Immunology.

Role of neuroendocrine hormones in murine T cell development. Growth hormone exerts thymopoietic effects in vivo.

D. Longo, S. Durum, W. Murphy, 1992, Journal of immunology.

Activated natural killer cells and interleukin-2 promote granulocytic and megakaryocytic reconstitution after syngeneic bone marrow transplantation in mice.

Craig W. Reynolds, D. Longo, W. Murphy, 1993, Blood.

Analysis of expression and promoter function of the human inducible nitric oxide synthase gene in DLD-1 cells and monkey hepatocytes.

S. Russell, W. Murphy, V. Laubach, 1997, Biochimica et biophysica acta.

An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide.

T. Parmely, D. Morrison, S. Russell, 1997, The Journal of biological chemistry.

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans.

J. Byrd, G. Freeman, J. Ritz, 2014, Blood.

Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans.

J. Ritz, M. Shlomchik, J. Browning, 2012, Blood.

IL-6 induction of protein-DNA complexes via a novel regulatory region of the inducible nitric oxide synthase gene promoter: role of octamer binding proteins.

W. Murphy, P. Rao, D. H. Pluznik, 1997, Journal of immunology.

Iron Is a Regulatory Component of Human IL-1 β Production

W. Murphy, S. R. Nelson, A. O'Brien-Ladner, 2000 .

Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immune deficiency (SCID).

D. Longo, J. O’Shea, H. Young, 1994, Journal of immunology.

The role of growth hormone in T‐cell development and reconstitution

W. Murphy, R. Sun, L. Welniak, 2002, Journal of leukocyte biology.

Interleukin-2-activated natural killer cells can support hematopoiesis in vitro and promote marrow engraftment in vivo.

D. Longo, J. Keller, W. Murphy, 1992, Blood.

An absence of T cells in murine bone marrow allografts leads to an increased susceptibility to rejection by natural killer cells and T cells.

W. Murphy, M. Bennett, V. Kumar, 1990, Journal of immunology.

Immunobiology of bone marrow transplantation: studies using scid mice.

W. Murphy, M. Bennett, V. Kumar, 1989, Current topics in microbiology and immunology.

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner.

J. Ritz, D. Munn, J. Serody, 2016, Blood.

Gastrointestinal Cells of IL-7 Receptor Null Mice Exhibit Increased Sensitivity to Irradiation1

M. Anver, A. Khaled, S. Durum, 2001, The Journal of Immunology.

IrradiationMice Exhibit Increased Sensitivity to Gastrointestinal Cells of IL-7 Receptor Null

M. Anver, A. Khaled, S. Durum, 2001 .

A classical enhancer element responsive to both lipopolysaccharide and interferon-gamma augments induction of the iNOS gene in mouse macrophages.

S. Russell, W. Murphy, E. Alley, 1995, Gene.

Being “penny-wise but pound foolish” in cancer immunotherapy research: the urgent need for mouse cancer models to reflect human modifying factors

W. Murphy, 2016, Journal of Immunotherapy for Cancer.

Synergistic Anti-Tumor Responses After Administration of Agonistic Antibodies to CD40 and IL-2: Coordination of Dendritic and CD8+ Cell Responses 1

J. Wigginton, T. Sayers, T. Back, 2003, The Journal of Immunology.

Canine and Feline Parvoviruses Can Use Human or Feline Transferrin Receptors To Bind, Enter, and Infect Cells

C. Parrish, W. Murphy, D. Wang, 2001, Journal of Virology.

In Vivo Models of Allogeneic Hematopoietic Stem Cell Transplantation

W. Murphy, L. Welniak, 2010 .

IFN-γ mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy

J. Weiss, D. Longo, T. Back, 2007, Nature Medicine.

Immune targeting of cancer stem cells in gastrointestinal oncology.

W. Murphy, R. Canter, E. Ames, 2016, Journal of gastrointestinal oncology.

NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

T. Sayers, W. Murphy, Mingyi Chen, 2015, The Journal of Immunology.

with a Cancer Stem Cell Phenotype NK Cells Preferentially Target Tumor Cells

T. Sayers, W. Murphy, Mingyi Chen, 2015 .

The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality.

M. Konopleva, M. Andreeff, S. Kornblau, 2007, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes.

D. Taub, D. Longo, M. Anver, 1995, The Journal of clinical investigation.

Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity.

D. Longo, T. Sayers, A. Brooks, 2015, Cancer research.

CD40 Stimulation and Antitumor Effects

W. Murphy, Danice E. C. Wilkins, 2009 .

Natural Killer Cells and Their Role in Hematopoietic Stem Cell Transplantation

W. Murphy, Deborah Goetz, 2010 .

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/αCD40 Therapy

J. Weiss, T. Sayers, S. K. Watkins, 2014, The Journal of Immunology.

Regulatory T Cells and Myeloid-Derived Suppressor Cells in the Tumor Microenvironment Undergo Fas-Dependent Cell Death during IL-2/aCD40 Therapy

J. Weiss, T. Sayers, S. K. Watkins, 2014 .

Cell Death during IL-2/ Microenvironment Undergo Fas-Dependent Suppressor Cells in the Tumor Regulatory T Cells and Myeloid-Derived

J. Weiss, T. Sayers, S. K. Watkins, 2014 .

Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax.

D. Taub, D. Longo, A. Khaled, 2002, Blood.

Ex vivo Inhibition of NF‐κB Signaling in Alloreactive T‐cells Prevents Graft‐Versus‐Host Disease

J. Serody, E. Palmer, B. Jaffee, 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Mouse Preclinical Cancer Immunotherapy Modeling Involving Anti-PD-1 Therapies Reveals the Need to Use Mouse Reagents to Mirror Clinical Paradigms

W. Murphy, A. Monjazeb, Lam T. Khuat, 2021, Cancers.

Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody.

Carlos A. Tristan, P. Elliott, T. Sayers, 2008, Journal of the National Cancer Institute.

mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia.

Suzanne M. Brandt, T. Kozel, W. Murphy, 2004, Proceedings of the National Academy of Sciences of the United States of America.

UVB light suppresses nitric oxide production by murine keratinocytes and macrophages.

D. Heck, W. Murphy, J. Laskin, 2002, Biochemical pharmacology.

Mouse host unlicensed NK cells promote donor allogeneic bone marrow engraftment.

W. Murphy, K. Sun, Maite Alvarez, 2016, Blood.

Impact of aging in cancer immunotherapy

W. Murphy, M. Bouchlaka, 2013, Oncoimmunology.

Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy.

J. Weiss, D. Longo, L. Lanier, 2012, Blood.

Program death-1 (PD-1) signaling and regulatory T cells (Tregs) collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes (CTLs) in advanced acute myeloid leukemia (AML) Running title: PD-1 blockade and adoptive CTL therapy for AML

D. Munn, J. Tolar, C. June, 2010 .

Inhaled recombinant human IL-15 in dogs with naturally occurring pulmonary metastases from osteosarcoma or melanoma: a phase 1 study of clinical activity and correlates of response

S. Stewart, K. Woolard, R. Rebhun, 2022, Journal for ImmunoTherapy of Cancer.

transplantation in mice and megakaryocytic reconstitution after syngeneic bone marrow Activated natural killer cells and interleukin-2 promote granulocytic

D. Longo, W. Murphy, C. Reynolds, 2011 .

The potential role of NK cells in the separation of graft‐versus‐tumor effects from graft‐versus‐host disease after allogeneic bone marrow transplantation

D. Longo, W. Murphy, 1997, Immunological reviews.

Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo.

W. Murphy, B. Blazar, T. George, 2001, Blood.

The triterpenoid CDDO-Me delays murine acute graft-versus-host disease with the preservation of graft-versus-tumor effects after allogeneic bone marrow transplantation.

W. Murphy, K. Sun, L. Welniak, 2010, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Myelodysplastic Syndrome : The Transplanter ’ s Quandaries

W. Murphy, S. Devine, C. Anasetti, 2008 .

Endothelial + Responses by Human CCR3 Eotaxin (CCL11) Induces In Vivo Angiogenic

J. Ward, H. Kleinman, H. Young, 2022 .

NK inhibitory-receptor blockade for purging of leukemia: effects on hematopoietic reconstitution.

W. Murphy, B. Blazar, L. Welniak, 2002, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Natural killer cells and bone marrow transplantation.

Craig W. Reynolds, D. Longo, P. Tiberghien, 1993, Journal of the National Cancer Institute.

Recombinant Human Growth Hormone Promotes Hematopoietic Reconstitution after Syngeneic Bone Marrow Transplantation in Mice

D. Longo, W. Murphy, R. Sun, 1998, Stem cells.

Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC.

L. Lanier, S. Anderson, W. Murphy, 2011, Blood.

Activation status dictates the function of unlicensed natural killer cells in mice and humans

P. Chevallier, C. Retière, Jeffrey S. Miller, 2021, Blood advances.

Differential expression of the Ly49G(B6), but not the Ly49G(BALB), receptor isoform during natural killer cell reconstitution after hematopoietic stem cell transplantation.

S. Anderson, W. Murphy, Can M Sungur, 2013, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Differential expression of the Ly49G B6 and not Ly49G receptor isoform during NK cell reconstitution after hematopoietic stem cell transplantation

S. Anderson, W. Murphy, Can M Sungur, 2013 .

Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens.

D. Longo, J. Ortaldo, W. Murphy, 2002, Blood.

Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2b bone marrow cell allografts

D. Longo, J. Ortaldo, W. Murphy, 2000 .

Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts.

D. Longo, J. Ortaldo, W. Murphy, 2000, Blood.

Differential effects of the rejection of bone marrow allografts by the depletion of activating versus inhibiting Ly-49 natural killer cell subsets.

D. Longo, J. Ortaldo, W. Murphy, 1998, Journal of immunology.

SubsetsVersus Inhibiting Ly-49 Natural Killer Cell Marrow Allografts by the Depletion of Activating Differential Effects of the Rejection of Bone

D. Longo, J. Ortaldo, W. Murphy, 1997 .

Models to Study NK Cell Biology and Possible Clinical Application

W. Murphy, Anthony E. Zamora, S. Grossenbacher, 2015, Current protocols in immunology.

Contrasting Effects of Anti-Ly49A Due to MHC Class I cis Binding on NK Cell–Mediated Allogeneic Bone Marrow Cell Resistance

S. Anderson, W. Murphy, Can M Sungur, 2013, The Journal of Immunology.

Ly-49 G2+ NK cells are responsible for mediating the rejection of H-2b bone marrow allografts in mice.

D. Longo, J. Ortaldo, W. Murphy, 1996, International immunology.

Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment

J. Weiss, J. Stauffer, T. Back, 2009, Proceedings of the National Academy of Sciences.

A Possible Role for Anti-idiotype Antibodies in SARS-CoV-2 Infection and Vaccination.

D. Longo, W. Murphy, 2021, The New England journal of medicine.

Minimal PD-1 expression in mouse and human NK cells under diverse conditions.

D. Longo, J. Serody, S. Anderson, 2020, The Journal of clinical investigation.

Interaction with vesicular stomatitis virus‐infected BALB/c3T3 cells inhibits the synthesis of nitric oxide in activated murine bone marrow culture‐derived macrophages

S. Russell, W. Murphy, P. LeBlanc, 1999, Journal of leukocyte biology.

Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation.

J. Weiss, J. Ortaldo, R. Wiltrout, 2011, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Targeting PI3Kδ function for amelioration of murine chronic graft‐versus‐host disease

J. Byrd, K. Okkenhaug, J. Ritz, 2019, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease.

J. Byrd, J. Ritz, D. Munn, 2014, The Journal of clinical investigation.

Chronic graft-versus-host disease (cGVHD) is a life-threatening impediment to allogeneic hematopoietic stem cell transplantation, and current therapies do not completely prevent and/or treat cGVHD. CD4

J. Byrd, J. Ritz, D. Munn, 2014 .

Expansion of LTC‐ICs and Maintenance of p21 and BCL‐2 Expression in Cord Blood CD34+/CD38− Early Progenitors Cultured over Human MSCs as a Feeder Layer

P. Fu, W. Murphy, S. Haynesworth, 2002, Stem cells.

Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin‐like growth factor in HIV‐infected patients

D. Longo, M. Baseler, D. Venzon, 1998, AIDS.

Growth hormone promotes human T cell adhesion and migration to both human and murine matrix proteins in vitro and directly promotes xenogeneic engraftment.

D. Taub, D. Longo, S. Durum, 1994, The Journal of clinical investigation.

Human growth hormone promotes engraftment of murine or human T cells in severe combined immunodeficient mice.

D. Longo, S. Durum, W. Murphy, 1992, Proceedings of the National Academy of Sciences of the United States of America.

IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation

W. Murphy, Lam T. Khuat, I. Barão, 2020, Cancers.

azidothymidine vivo and partially counteracts the myelosuppressive effects of Growth hormone exerts hematopoietic growth-promoting effects in

D. Longo, W. Murphy, G. Tsarfaty, 2011 .

Prolactin exerts hematopoietic growth-promoting effects in vivo and partially counteracts myelosuppression by azidothymidine.

D. Longo, W. Murphy, R. Sun, 1999, Experimental hematology.

Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine.

D. Longo, W. Murphy, G. Tsarfaty, 1992, Blood.

Bystander Activation and Anti-Tumor Effects of CD8+ T Cells Following Interleukin-2 Based Immunotherapy Is Independent of CD4+ T Cell Help

J. Weiss, R. Wiltrout, W. Murphy, 2014, PloS one.

Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells.

H. Young, W. Murphy, R. Salcedo, 2003, Blood.

Effects of organ-specific loss of insulin-like growth factor-I production on murine hematopoiesis.

D. Leroith, M. Anver, M. Karas, 2004, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Immune response and immunotherapy to Cryptococcus infections

W. Murphy, Qing Zhou, 2006, Immunologic research.

Adoptive cellular immunotherapy: NK cells and bone marrow transplantation.

W. Murphy, L. Welniak, C. Y. Koh, 2000, Histology and histopathology.

Induction of CD 4 1 T Cell Alloantigen-Specific Hyporesponsiveness by IL-10 and TGF-b 1

F. Ruscetti, M. Roncarolo, S. Narula, 1999 .

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease.

J. Ritz, J. Serody, R. Soiffer, 2015, Blood.

Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation?

Craig W. Reynolds, M. Deschaseaux, Y. Chiang, 1994, Blood.

Activation of the iNOS gene promoter by Brn-3 POU family transcription factors is dependent upon the octamer motif in the promoter.

D. Latchman, S. Russell, W. Murphy, 1998, Biochimica et biophysica acta.

Bacterial Lipopolysaccharide Selectively Up-Regulates the Function of the Chemotactic Peptide Receptor Formyl Peptide Receptor 2 in Murine Microglial Cells1

W. Gong, Ji Ming Wang, P. Proost, 2002, The Journal of Immunology.

Therapeutic benefit of bortezomib on acute graft-versus-host disease is tissue specific and is associated with interleukin-6 levels.

W. Murphy, J. Tellez, B. Blazar, 2014, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Therapeutic benefit of bortezomib on acute GVHD is tissue specific and is associated with IL-6 levels Blood Marrow

W. Murphy, J. Tellez, B. Blazar, 2014 .

Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network.

D. Taub, W. Murphy, L. Welniak, 2008, Cellular immunology.

Rejuvenation of the Aging Thymus : Growth Hormone-and Ghrelin-Mediated Signaling Pathways

D. Taub, D. Longo, W. Murphy, 2010 .

NK cell subsets in the regulation of murine hematopoiesis. I. 5E6+ NK cells promote hematopoietic growth in H-2d strain mice.

D. Longo, W. Murphy, M. Bennett, 1995, Journal of immunology.

Regulation of murine NK cell exhaustion through the activation of the DNA damage repair pathway.

R. Negrin, W. Murphy, J. Baker, 2019, JCI insight.

Mouse NK cell-mediated rejection of bone marrow allografts exhibits patterns consistent with Ly49 subset licensing.

D. Longo, W. Murphy, Mingyi Chen, 2012, Blood.

Use of Distinct TCR-Binding Ceramides Induction, and NK Activation In Vivo by the Dissociation of NKT Stimulation, Cytokine

H. Young, J. Ortaldo, R. Wiltrout, 2003 .

The triterpenoid CDDO-Me promotes hematopoietic progenitor expansion and myelopoiesis in mice.

W. Murphy, C. Meyer, E. Ames, 2012, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

TRANSPLANTATION Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

J. Ritz, J. Serody, R. Soiffer, 2015 .

Priming is key to effective incorporation of image-guided thermal ablation into immunotherapy protocols.

A. Borowsky, W. Murphy, L. Mahakian, 2017, JCI insight.

In vivo antitumor effects of unconjugated CD30 monoclonal antibodies on human anaplastic large-cell lymphoma xenografts.

D. Longo, D. Ferris, W. Murphy, 1995, Cancer research.

Activated allogeneic NK cells as suppressors of alloreactive responses.

W. Murphy, Haiyan Liu, L. Welniak, 2004, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury.

D. Lacey, A. Üren, J. Rubin, 2000, Blood.

Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha.

H. Kleinman, H. Young, M. Anver, 1999, The American journal of pathology.

The Proteasome Inhibitor Bortezomib (Velcade) Sensitizes Some Human Tumor Cells to Apo2L/TRAIL‐Mediated Apoptosis

P. Elliott, T. Sayers, A. Brooks, 2005, Annals of the New York Academy of Sciences.

Prolonged exposure of mouse macrophages to IFN‐β suppresses transcription of the inducible nitric oxide synthase gene: altered availability of transcription factor Stat1α

J. Gao, S. Russell, W. Murphy, 2000, European journal of immunology.

Autoimmune T cells lured to a FASL web of death by MSCs.

J. Nolta, W. Murphy, 2012, Cell stem cell.

Cloning Thymic Precursor Cells: Demonstration That Individual Pro-T1 Cells Have Dual T–NK Potential and Individual Pro-T2 Cells Have Dual αβ–γδ T Cell Potential

K. Muegge, S. Durum, W. Murphy, 1999 .

Delineation of antigen-speciﬁc and antigen-nonspeciﬁc CD8 (cid:1) memory T-cell responses after cytokine-based cancer immunotherapy

J. Weiss, D. Longo, L. Lanier, 2012 .

The diverse role of chemokines in tumor progression: prospects for intervention (Review).

W. Murphy, R. Salcedo, L. Welniak, 2001, International journal of molecular medicine.

transplantation continuous bortezomib administration after allogeneic bone marrow Differential effects of donor T-cell cytokines on outcome with

T. Sayers, W. Murphy, K. Sun, 2013 .

Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation.

T. Sayers, W. Murphy, K. Sun, 2008, Blood.

Murine Microglial Cells Peptide Receptor Formyl Peptide Receptor 2 ChemotacticUp-Regulates the Function of the Bacterial Lipopolysaccharide Selectively

W. Gong, Ji Ming Wang, P. Proost, 2001 .

Low responsiveness to IFN‐γ, after pretreatment of mouse macrophages with lipopolysaccharides, develops via diverse regulatory pathways

W. Murphy, M. Filla, A. Crespo, 2002, European journal of immunology.

Tumor regression by anti-CD40 and interleukin-2: role of CD40 in hematopoietic cells and organ-specific effects.

R. Wiltrout, W. Murphy, B. Blazar, 2004, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Role for CD40-CD40 ligand interactions in the immune response to solid tumours.

D. Taub, D. Longo, W. Murphy, 2000, Molecular immunology.

Immunomodulation with CD40 Stimulation and Interleukin-2 Protects Mice from Disseminated Cryptococcosis

T. Kozel, W. Murphy, Qing Zhou, 2006, Infection and Immunity.

An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease.

M. Anver, W. Kuziel, W. Murphy, 2004, Experimental hematology.

Treatment of chronic graft-versus-host disease with bortezomib.

J. Jagdeo, W. Murphy, J. Tellez, 2014, Blood.

Effects of Growth Hormone and Prolactin on Hematopoiesis

F. Ruscetti, J. Keller, W. Murphy, 2000, Leukemia & lymphoma.

Use of Neuroendocrine Hormones to Promote Reconstitution after Bone Marrow Transplantation

D. Taub, D. Longo, W. Murphy, 1999, Neuroimmunomodulation.

Chemokines and T lymphocyte activation: II. Facilitation of human T cell trafficking in severe combined immunodeficiency mice.

D. Taub, D. Longo, R. Strieter, 1996, Journal of immunology.

Effects of growth hormone and prolactin immune development and function.

D. Longo, W. Murphy, H. Rui, 1995, Life sciences.

Immunologic and hematologic effects of neuroendocrine hormones. Studies on DW/J dwarf mice.

D. Longo, M. Anver, S. Durum, 1992, Journal of immunology.

Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality

P. Chambon, D. Munn, J. Serody, 2019, The Journal of Immunology.

New Strategies for Fungal Infections after Hematopoietic Cell Transplantation : Prevention or Preemption ?

Treasurer, H. Heslop, R. Soiffer, 2007 .

IFN-γ Receptor-Deficient Donor T Cells Mediate Protection from Graft-versus-Host Disease and Preserve Graft-versus-Tumor Responses after Allogeneic Bone Marrow Transplantation

J. Jagdeo, W. Murphy, B. Blazar, 2012, The Journal of Immunology.

IFN-g Receptor-Deficient Donor T Cells Mediate Protection from Graft-versus-Host Disease and Preserve Graft-versus-Tumor Responses after Allogeneic Bone Marrow Transplantation

J. Jagdeo, W. Murphy, B. Blazar, 2012 .

Transplantation Responses after Allogeneic Bone Marrow Disease and Preserve Graft-versus-tumor Mediate Protection from Graft-versus-host Receptor-deficient Donor T Cells Γ Ifn

J. Jagdeo, W. Murphy, B. Blazar, 2022 .

Inhibition of human breast carcinoma growth by a soluble recombinant human CD40 ligand.

D. Taub, D. Longo, L. Young, 1999, Blood.

Immunobiology of natural killer cells and bone marrow transplantation: merging of basic and preclinical studies

D. Longo, W. Murphy, M. Bennett, 2001, Immunological reviews.

Co-expression of Tim-3 and PD-1 Identifies a CD8+T-Cell Exhaustion Phenotype in Mice with Disseminated Acute Myelogenous Leukemia

D. Munn, V. Kuchroo, W. Murphy, 2011 .

Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.

M. Anver, R. Wiltrout, W. Murphy, 2002, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Eotaxin (CCL11) Induces In Vivo Angiogenic Responses by Human CCR3+ Endothelial Cells1

J. Ward, H. Kleinman, H. Young, 2001, The Journal of Immunology.

Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression.

J. Ward, H. Kleinman, H. Young, 2000, Blood.

Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha.

H. Kleinman, H. Young, M. Anver, 1999, The American journal of pathology.

Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.

S. Snyder, C. Lowenstein, S. Russell, 1993, The Journal of biological chemistry.

Protection from Direct Cerebral Cryptococcus Infection by Interferon-γ-Dependent Activation of Microglial Cells1

T. Kozel, W. Murphy, Qing Zhou, 2007, The Journal of Immunology.

Enabling Technologies for Cell-Based Clinical Translation Therapeutic Efficacy of Fresh , Autologous Mesenchymal Stem Cells for Severe Refractory Gingivostomatitis in Cats

Murphy, Naomi, N. Vapniarsky, 2015 .

Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies.

K. Peggs, M. Boeckh, W. Murphy, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Opposing roles of interferon-gamma on CD4+ T cell-mediated graft-versus-host disease: effects of conditioning.

M. Anver, R. Wiltrout, W. Murphy, 2000, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Chemokine-induced human lymphocyte infiltration and engraftment in huPBL-SCID mice.

D. Taub, D. Longo, W. Murphy, 1997, Methods in enzymology.

A candidate interferon-gamma activated site (GAS element) in the HLA-G promoter does not bind nuclear proteins.

W. Murphy, J. S. Hunt, W. Chu, 1999, Human immunology.

Defining the critical hurdles in cancer immunotherapy

Zhigang Tian, Sylvia Janetzki, Cedrik M Britten, 2011, Journal of Translational Medicine.

Progesterone inhibits inducible nitric oxide synthase gene expression and nitric oxide production in murine macrophages

S. Russell, W. Murphy, J. S. Hunt, 1996, Journal of leukocyte biology.

Cellular and molecular pathways in the tumor immunoenvironment: 3rd Cancer Immunotherapy and Immunomonitoring (CITIM) meeting, 22–25 April 2013, Krakow, Poland

W. Murphy, R. Apte, M. Shurin, 2013, Cancer Immunology, Immunotherapy.

Comparative Immunogenomics of Canine Natural Killer Cells as Immunotherapy Target

R. Rebhun, W. Murphy, Kevin M. Stoffel, 2021, Frontiers in Immunology.

Blood and tissue biomarker analysis in dogs with osteosarcoma treated with palliative radiation and intra-tumoral autologous natural killer cell transfer

J. Modiano, R. Rebhun, W. Murphy, 2019, bioRxiv.

Targeting Cancer Stem Cells with Natural Killer Cell Immunotherapy

Jesus I. Luna, W. Murphy, R. Canter, 2017, Expert opinion on biological therapy.

Canine cancer immunotherapy studies: linking mouse and human

J. Modiano, R. Rebhun, Jesus I. Luna, 2016, Journal of Immunotherapy for Cancer.

Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells

Jesus I. Luna, W. Murphy, R. Canter, 2019, Cancers.

Immunobiology of allogeneic hematopoietic stem cell transplantation.

W. Murphy, B. Blazar, L. Welniak, 2007, Annual review of immunology.

Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new.

J. Serody, W. Murphy, B. Blazar, 2011, Blood.

LRIG1 opposes epithelial to mesenchymal transition and inhibits invasion of basal-like breast cancer cells

W. Murphy, J. Tellez, K. Carraway, 2015, Oncogene.

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GvHD.

D. Munn, J. Serody, S. Jameson, 2019, Blood.

Alterations in cancer stem-cell marker CD44 expression predict oncologic outcome in soft-tissue sarcomas.

Chin-Shang Li, W. Murphy, Mingyi Chen, 2018, The Journal of surgical research.

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.

D. Munn, V. Kuchroo, M. Hirashima, 2011, Blood.

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

S. Vesely, D. Longo, R. Isseroff, 2018, Nature Medicine.

Characterizing the Dysfunctional NK Cell: Assessing the Clinical Relevance of Exhaustion, Anergy, and Senescence

W. Murphy, R. Canter, S. Judge, 2020, Frontiers in Cellular and Infection Microbiology.

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy

A. Borowsky, W. Murphy, B. Blazar, 2017, Journal of Immunotherapy for Cancer.

Immunoregulatory pathways following strong inflammatory processes markedly impair CD4+ T cell responses

W. Murphy, Christine M Minnar, 2016, Human Vaccines & Immunotherapeutics.

Influenza infection results in local expansion of memory CD8+ T cells with antigen non‐specific phenotype and function

L. Lanier, W. Murphy, N. Baumgarth, 2014, Clinical and experimental immunology.

Hematopoietic growth-promoting effects of natural killer cells in mice in response to in vivo administration of human interleukin-2.

D. Longo, W. Murphy, 1992, Journal of the National Cancer Institute.

Donor-type activated natural killer cells promote marrow engraftment and B cell development during allogeneic bone marrow transplantation.

D. Longo, W. Murphy, M. Bennett, 1992, Journal of immunology.

Rejection of bone marrow allografts by mice with severe combined immune deficiency (SCID). Evidence that natural killer cells can mediate the specificity of marrow graft rejection

W. Murphy, M. Bennett, M. Bennett, 1987, The Journal of experimental medicine.

Lack of correlation between an assay used to determine early marrow allograft rejection and long-term chimerism after murine allogeneic bone marrow transplantation: effects of marrow dose.

W. Murphy, L. Welniak, C. Koh, 2005, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Natural killer cells activated with interleukin 2 in vitro can be adoptively transferred and mediate hematopoietic histocompatibility‐1 antigen‐specific bone marrow rejection in vivo

W. Murphy, Vinay Kumar, M. Bennett, 1990, European journal of immunology.

Differential in vitro and in vivo antitumor effects mediated by anti-CD40 and anti-CD20 monoclonal antibodies against human B-cell lymphomas.

D. Longo, W. Murphy, S. Funakoshi, 1996, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

Epstein-Barr virus-induced human B-cell lymphoma arising in HuPBL-SCID chimeric mice: characterization and the role of CD40 stimulation in their treatment and prevention.

D. Longo, M. Beckwith, W. Murphy, 1995, Pathobiology : journal of immunopathology, molecular and cellular biology.

Immunologic and hematopoietic effects of recombinant human prolactin after syngeneic bone marrow transplantation in mice.

W. Murphy, R. Sun, S. Richards, 2003, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Potential applications of growth hormone in promoting immune reconstitution

W. Murphy, R. Sun, L. Welniak, 2002 .

Growth hormone as an immunomodulating therapeutic agent.

D. Longo, W. Murphy, 2000, Immunology today.

Human insulin-like growth factor I exerts hematopoietic growth-promoting effects after in vivo administration.

D. Longo, W. Murphy, G. Tsarfaty, 1994, Experimental hematology.

Advances in graft-versus-host disease biology and therapy

Bruce R. Blazar, William J. Murphy, Mehrdad Abedi, 2012, Nature Reviews Immunology.

Proteasome inhibition and allogeneic hematopoietic stem cell transplantation: a review.

W. Murphy, L. Welniak, E. Alyea, 2009, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

The Use of Cytokine Knockout Mice in Cancer Research

J. Wigginton, R. Wiltrout, W. Murphy, 2003 .

Role of interleukin-12 in acute graft-versus-host disease(1).

M. Anver, R. Wiltrout, W. Murphy, 2001, Transplantation proceedings.

Revisiting graft-versus-host disease models of autoimmunity: new insights in immune regulatory processes.

W. Murphy, 2000, The Journal of clinical investigation.

Infusions Disease Mediated by Donor Leukocyte Host T Cells Resist Graft-Versus-Host

B. Kwon, R. Noelle, W. Murphy, 2000 .

New strategies for preventing graft-versus-host disease.

W. Murphy, B. Blazar, William J. Murphy, 1999, Current opinion in immunology.

Effects of housing on the thymic deficiency in dwarf mice and its reversal by growth hormone administration.

W. Murphy, N. Horseman, E. Montecino-Rodriguez, 2003, Clinical immunology.

Use of human prolactin as a therapeutic protein to potentiate immunohematopoietic function

W. Murphy, S. Richards, 2000, Journal of Neuroimmunology.

Differential effects of growth hormone and prolactin on murine T cell development and function

D. Longo, S. Durum, W. Murphy, 1993, The Journal of experimental medicine.

Phenotype in Mice with Disseminated Acute Myelogenous Leukemia Running title: PD-1+Tim-3+ CD8+T-cells induced by AML are dysfunctional

D. Munn, V. Kuchroo, W. Murphy, 2011 .

Western Diet-Induced Dysbiosis in Farnesoid X Receptor Knockout Mice Causes Persistent Hepatic Inflammation after Antibiotic Treatment.

V. Krishnan, K. Kalanetra, D. Mills, 2017, The American journal of pathology.

Engraftment of SCID mice by human bone marrow hematopoietic cells cultured in vitro: an in vivo model for human gene transfer.

D. Longo, J. Keller, W. Murphy, 1995, Leukemia.

Prospects for cytokine and chemokine biotherapy.

W. Murphy, J. Wang, V. Schirrmacher, 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

Cell Responses + and CD8 CD40 and IL-2: Coordination of Dendritic Administration of Agonistic Antibodies to Synergistic Anti-Tumor Responses After

J. Wigginton, T. Sayers, T. Back, 2003 .

IMMUNOBIOLOGY Inhibition of Human Breast Carcinoma Growth by a Soluble Recombinant Human CD 40 Ligand

D. Taub, D. Longo, L. Young, 1999 .

Proteasome Inhibition: Potential for Sensitization of Immune Effector Mechanisms in Cancer

W. Murphy, W. Hallett, Minghui Li, 2008 .

Rejuvenation of the aging thymus: growth hormone-mediated and ghrelin-mediated signaling pathways.

William J Murphy, D. Taub, D. Longo, 2010, Current opinion in pharmacology.

in vitro and promote marrow engraftment in vivo Interleukin-2-activated natural killer cells can support hematopoiesis

D. Longo, J. Keller, W. Murphy, 2011 .

Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome

C. Tepper, B. Arzi, W. Murphy, 2017, Stem Cell Research & Therapy.

Cellular and molecular studies in the treatment of murine renal cancer.

D. Longo, R. Fenton, R. Wiltrout, 1995, Seminars in oncology.

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

D. Munn, J. Tolar, B. Levine, 2010, Blood.

β Chemokines costimulate lymphocyte cytolysis, proliferation, and lymphokine production

D. Taub, D. Longo, J. Ortaldo, 1996, Journal of leukocyte biology.

Tyrphostin AG‐490 inhibits cytokine‐mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen‐activated human T cells

D. Taub, W. Farrar, R. Kirken, 1999, Journal of leukocyte biology.

Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation.

D. Lacey, R. Strieter, W. Murphy, 2000, Blood.

The emerging roles of the gut microbiome in allogeneic hematopoietic stem cell transplantation

M. Dave, W. Murphy, Lam T. Khuat, 2021, Gut microbes.

Improving classification of melanocytic nevi: Association of BRAF V600E expression with distinct histomorphologic features

J. McPherson, L. Qi, Lan Yu, 2018, Journal of the American Academy of Dermatology.

The Graying of Clinical Transplantation

Treasurer, H. Heslop, R. Soiffer, 2006 .

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.

J. Weiss, J. Ritz, D. Munn, 2016, Blood.

Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta.

F. Ruscetti, M. Roncarolo, S. Narula, 1999, Journal of immunology.

Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity.

J. Serody, D. Littman, G. Hill, 2023, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Antibodies to CD40 induce a lethal cytokine cascade after syngeneic bone marrow transplantation.

M. Anver, R. Wiltrout, W. Murphy, 2001, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Differential effects of CD40 stimulation on normal and neoplastic cell growth.

W. Murphy, A. Boyd, J. Hixon, 2000, Archivum immunologiae et therapiae experimentalis.

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.

S. Akira, J. Serody, A. Sharpe, 2008, Blood.

Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide.

S. Snyder, C. Lowenstein, A. Snowman, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Multi‐color flow cytometry for evaluating age‐related changes in memory lymphocyte subsets in dogs

R. Rebhun, P. Moore, W. Murphy, 2018, Developmental and comparative immunology.

Development of preclinical and clinical models for immune-related adverse events following checkpoint immunotherapy: a perspective from SITC and AACR

Theresa L. Walunas, A. Villani, E. Jaffee, 2021, Journal for ImmunoTherapy of Cancer.

An Interferon-γ-activated Site (GAS) Is Necessary for Full Expression of the Mouse iNOS Gene in Response to Interferon-γ and Lipopolysaccharide*

T. Parmely, Jianjun Gao, D. Morrison, 1997, The Journal of Biological Chemistry.

High fluence light emitting diode‐generated red light modulates characteristics associated with skin fibrosis

R. Isseroff, A. Mamalis, J. Jagdeo, 2016, Journal of biophotonics.

Leveraging natural killer cells for cancer immunotherapy.

W. Murphy, S. Grossenbacher, Ethan G. Aguilar, 2017, Immunotherapy.

Stimulation through CD40 on Mouse and Human Renal Cell Carcinomas Triggers Cytokine Production, Leukocyte Recruitment, and Antitumor Responses that Can Be Independent of Host CD40 Expression12

J. Weiss, T. Back, R. Wiltrout, 2006, The Journal of Immunology.

Cytokine Production , Leukocyte Human Renal Cell Carcinomas Triggers Stimulation through CD 40 on Mouse and

J. Weiss, T. Back, R. Wiltrout, 2006 .

Stimulation through CD 40 on Mouse and Human Renal Cell Carcinomas Triggers Cytokine Production , Leukocyte Recruitment , and Antitumor Responses that Can Be Independent of Host CD 40 Expression 1 , 2

J. Weiss, T. Back, R. Wiltrout, 2006 .

Constitutive expression of functional CD40 on mouse renal cancer cells: induction of Fas and Fas-mediated killing by CD40L.

T. Sayers, R. Wiltrout, W. Murphy, 2005, Cellular immunology.

Indirect induction of suppressor of cytokine signalling-1 in macrophages stimulated with bacterial lipopolysaccharide: partial role of autocrine/paracrine interferon-alpha/beta.

S. Russell, W. Murphy, M. Filla, 2000, The Biochemical journal.

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality.

G. Freeman, D. Munn, R. Ahmed, 2013, Blood.

Identification of Human Neutrophil-derived Cathepsin G and Azurocidin/CAP37 as Chemoattractants for Mononuclear Cells and Neutrophils

Ji Ming Wang, T. Sayers, W. Murphy, 1997, The Journal of experimental medicine.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

Charles J. Vaske, Rohan N. Borkar, Brian D. Kelly, 2016, Journal of Immunotherapy for Cancer.

The proportion of circulating CD45RO+CD8+ memory T cells is correlated with clinical response in melanoma patients treated with ipilimumab.

C. Berking, T. Ruzicka, W. Murphy, 2017, European journal of cancer.

Raising the spectra of T-cell profiling.

W. Murphy, 2008, Blood.

Down modulation of IFN-gamma signaling in alveolar macrophages isolated from smokers.

W. Murphy, M. Filla, A. O'Brien-Ladner, 2009, Toxicology and applied pharmacology.

Obesity induced T cell dysfunction and implications for cancer immunotherapy.

W. Murphy, Ethan G. Aguilar, 2018, Current opinion in immunology.

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality.

G. Freeman, S. Furlan, D. Munn, 2016, The Journal of clinical investigation.

Dissociation of NKT Stimulation, Cytokine Induction, and NK Activation In Vivo by the Use of Distinct TCR-Binding Ceramides1

H. Young, J. Ortaldo, R. Wiltrout, 2004, The Journal of Immunology.

Immunoediting and Antigen Loss: Overcoming the Achilles Heel of Immunotherapy with Antigen Non-Specific Therapies

W. Murphy, G. Sckisel, A. Monjazeb, 2013, Front. Oncol..

The role of antigen-specific and non-specific immunotherapy in the treatment of cancer

W. Murphy, H. Hsiao, G. Sckisel, 2012, Journal of immunotoxicology.

Adoptive immunotherapy involving recombinant human M-CSF and R24 anti-melanoma antibody induces human T-cell infiltration into human melanoma xenografts.

D. Longo, M. Anver, J. Ortaldo, 1996, Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy.

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation

A. Borowsky, C. Tepper, W. Murphy, 2018, Theranostics.

New Guidelines Help Health Professionals Recognize and Manage Late Complications

Treasurer, H. Heslop, R. Soiffer, 2006 .

Revisiting the paradigm on the putative need for antigen-specific responses in cancer

W. Murphy, J. Tietze, G. Sckisel, 2011 .

NK cells for PD-1/PD-L1 blockade immunotherapy: pinning down the NK cell.

W. Murphy, C. Dunai, 2018, The Journal of clinical investigation.

Obesity as an immune‐modifying factor in cancer immunotherapy

W. Murphy, R. Canter, Catherine T. Le, 2018, Journal of leukocyte biology.

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality.

G. Freeman, T. Mak, D. Munn, 2015, Blood.

Targeting BCL6 and Germinal Centers (GCs) in Chronic Graft-Versus-Host Disease (cGVHD) Using Direct and Epigenomic Therapies

J. Qi, J. Bradner, A. Melnick, 2014 .

Reprint of: Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies.

K. Peggs, M. Boeckh, W. Murphy, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Impact of Obesity and Aging on the Tumor Immuno-Environment

W. Murphy, G. Sckisel, A. Zamora, 2013 .

Induction of alloantigen-specific T cell tolerance through the treatment of human T lymphocytes with wortmannin.

D. Taub, D. Longo, G. Peltz, 1997, Journal of immunology.

Specificity may be overrated in cancer immunotherapy

W. Murphy, G. Sckisel, 2012, Oncoimmunology.

Regulatory and Conventional CD4+ T Cells Show Differential Effects Correlating with PD-1 and B7-H1 Expression after Immunotherapy12

J. Weiss, R. Wiltrout, W. Murphy, 2008, The Journal of Immunology.

Germinal Center Generation and Maintenance By T Follicular Helper Cells Is Required For The Development Of Chronic Gvhd Associated Bronchiolitis Obliterans In a Preclinical Model

J. Byrd, G. Freeman, J. Ritz, 2013 .

Antigen specific memory T cells and their putative need for the generation of sustained anti-tumor responses.

W. Murphy, Kory L. Alderson, 2010, Advances in experimental medicine and biology.

agonistic CD40 antibody administration transplant recipients from the lethal cytokine syndrome occurring after Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow

K. Pritchard, W. Murphy, B. Logan, 2013 .

Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration.

K. Pritchard, W. Murphy, B. Blazar, 2004, Blood.

Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies

S. Shiao, W. Murphy, J. Perks, 2016, Clinical Cancer Research.

Alternative strategies other than growth hormone for the treatment of immune diseases

D. Longo, W. Murphy, 2001 .

Mechanisms by Which Obesity Promotes Acute Graft-Versus-Host Disease in Mice

W. Murphy, B. Blazar, E. Maverakis, 2021, Frontiers in Immunology.

Correction: Attenuated Age-Impact on Systemic Inflammatory Markers in the Presence of a Metabolic Burden

L. Beckett, W. Murphy, L. Berglund, 2015, PloS one.

Characterization of the 5' flanking region and gene encoding the mouse interferon-gamma receptor.

S. Russell, S. Obici, W. Murphy, 1995, Gene.

Human soft tissue sarcomas harbor an intratumoral viral microbiome which is linked with natural killer cell infiltrate and prognosis

Nikhil A. Joshi, J. Eisen, S. Thorpe, 2023, Journal for ImmunoTherapy of Cancer.

TRAIL-mediated apoptosis by reducing levels of c-FLIP The proteasome inhibitor PS-341 sensitizes neoplastic cells to

P. Elliott, T. Sayers, A. Brooks, 2013 .

Inhibition of MDA-MB-231 human breast tumor xenografts and HER2 expression by anti-tumor agents GAP31 and MAP30.

S. Lee-Huang, H. Kung, W. Murphy, 2000, Anticancer research.

Immunotherapy With Magentorheologic Fluids

W. Murphy, C. Evrensel, 2011 .

Iron is a regulatory component of human IL-1beta production. Support for regional variability in the lung.

W. Murphy, S. R. Nelson, W J Murphy, 2000, American journal of respiratory cell and molecular biology.

Increased efficacy of dual pro-inflammatory cytokine blockade on acute GVHD while maintaining GVT effects.

D. Longo, M. Dave, W. Murphy, 2021, Blood.

Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation.

S. Nedospasov, D. Kuprash, W. Murphy, 2006, Blood.

Obesity and cancer immunotherapy toxicity.

W. Murphy, Annie Mirsoian, 2015, Immunotherapy.

Natural Killer Cell Subsets Differentially Reject Embryonic Stem Cells Based on Licensing

J. Nolta, W. Murphy, E. Ames, 2014, Transplantation.

Chemokine Blockade in Combination with Cytoreductive Conditioning in Metastatic Breast Cancer

W. Murphy, 2006 .

Androgen receptor blockade resistance with enzalutamide in prostate cancer results in immunosuppressive alterations in the tumor immune microenvironment

Xiong Zhang, W. Murphy, Hong-Wu Chen, 2023, Journal for ImmunoTherapy of Cancer.

BET-bromodomain and EZH2 inhibitor treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes.

J. Qi, J. Bradner, J. Ritz, 2022, Blood.

Metabolic Dysregulation Explains the Diverse Impacts of Obesity in Males and Females with Gastrointestinal Cancers

Song Liu, M. Churchman, S. Rosario, 2023, International journal of molecular sciences.

Erratum: Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib (Proceedings of the National Academy of Sciences of the United States of America (May 25, 2004) 101, 21 (8120-8125))

J. Serody, T. Sayers, W. Murphy, 2004 .

Giving alloHSCT a needed LIF(t).

W. Murphy, 2022, Blood.

Assessment of PD-1 expression in human resting and activated natural killer cells and murine tumor models.

W. Murphy, Kevin M. Stoffel, R. Canter, 2019, Journal of Clinical Oncology.

Multifaceted Effects of Obesity on Cancer Immunotherapies: Bridging Preclinical Models and Clinical Data.

W. Murphy, R. Canter, A. Monjazeb, 2023, Seminars in cancer biology.

Autocrine/paracrine IFN-alphabeta mediates the lipopolysaccharide-induced activation of transcription factor Stat1alpha in mouse macrophages: pivotal role of Stat1alpha in induction of the inducible nitric oxide synthase gene.

S. Vogel, S. Russell, W. Murphy, 1998, Journal of immunology.

Stereotactic Ablative Radiation Therapy Induces Systemic Differences in Peripheral Blood Immunophenotype Dependent on Irradiated Site.

K. Kelly, R. Valicenti, S. Stewart, 2018, International Journal of Radiation Oncology, Biology, Physics.

Intratumoral NKp46+ natural killer cells are spatially distanced from T and MHC-I+ cells with prognostic implications in soft tissue sarcoma

S. Thorpe, W. Murphy, R. Canter, 2023, Frontiers in immunology.

Drilling down interferon in GVHD/GVL.

W. Murphy, 2023, Blood.

Bringing out the DCs' softer side in GVHD.

W. Murphy, 2014, Blood.

Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Induce Expression of CXCR4 on Human Endothelial Cells: In Vivo Neovascularization Induced by Stromal-Derived Factor-1α

H. Kleinman, H. Young, M. Anver, 1999 .

Enhanced natural killer cell targeting of cancer stem cells using Cetuximab

W. Murphy, R. Canter, A. Monjazeb, 2014, Journal of Immunotherapy for Cancer.

Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens

D. Longo, J. Ortaldo, W. Murphy, 2002 .

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): late breaking abstracts

Amanda R. Campbell, F. Lund-Johansen, Yair Benita, 2016 .

Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry

Kit S Lam, Wei He, R Holland Cheng, 2013, Protein science : a publication of the Protein Society.

Of mice and men.

W. Murphy, 2013, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Advances in graft-versus-host disease biology and therapy

W. Murphy, B. Blazar, M. Abedi, 2012, Nature Reviews Immunology.

NK Cells in the Regulation of Hematopoiesis

D. Longo, W. Murphy, Murphy, 1996, Methods.

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.

S. Akira, J. Serody, A. Sharpe, 2008, Blood.

Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation.

T. Sayers, W. Murphy, K. Sun, 2008, Blood.

NK cells for PD-1/PD-L1 blockade immunotherapy: pinning down the NK cell.

W. Murphy, C. Dunai, 2018, The Journal of clinical investigation.

Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC.

L. Lanier, S. Anderson, W. Murphy, 2011, Blood.

Nitric oxide reduces early growth response-1 gene expression in rat lung macrophages treated with interferon-gamma and lipopolysaccharide.

L. Ignarro, M. Sherman, W. Murphy, 1994, The Journal of biological chemistry.

Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation.

D. Taub, D. Longo, F. Ruscetti, 1998, The Journal of clinical investigation.

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Charles J. Vaske, Joe Y. Chang, Scott R. Presnell, 2016, Journal for ImmunoTherapy of Cancer.

Mouse host unlicensed NK cells promote donor allogeneic bone marrow engraftment.

W. Murphy, K. Sun, Maite Álvarez, 2016, Blood.

Controlling the diameter, monodispersity, and solubility of ApoA1 nanolipoprotein particles using telodendrimer chemistry

L. Xing, R. Cheng, Juntao Luo, 2013, Protein science : a publication of the Protein Society.

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality.

D. Munn, R. Ahmed, A. Sharpe, 2013, Blood.

Stereotactic Ablative Radiation Therapy Induces Systemic Differences in Peripheral Blood Immunophenotype Dependent on Irradiated Site.

K. Kelly, R. Valicenti, S. Stewart, 2018, International journal of radiation oncology, biology, physics.

Regulation of murine NK cell exhaustion through the activation of the DNA damage repair pathway.

R. Negrin, W. Murphy, J. Baker, 2019, JCI insight.

Adoptive cellular immunotherapy: NK cells and bone marrow transplantation.

W. Murphy, L. Welniak, C. Y. Koh, 2000, Histology and histopathology.

Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies.

K. Peggs, M. Boeckh, W. Murphy, 2015, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Adoptive cellular immunotherapy : NK cells and bone marrow transplantation

W. Murphy, L. Welniak, C. Y. Koh, 2010 .

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality.

T. Mak, D. Munn, J. Serody, 2015, Blood.

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease.

J. Ritz, J. Serody, R. Soiffer, 2015, Blood.

TRAIL-mediated apoptosis by reducing levels of c-FLIP The proteasome inhibitor PS-341 sensitizes neoplastic cells to

P. Elliott, T. Sayers, A. Brooks, 2013 .

Use of systemic proteasome inhibition as an immune-modulating agent in disease.

W. Murphy, R. A. Gault, Lauren H. Mattingly, 2007, Endocrine, metabolic & immune disorders drug targets.

Obesity results in higher PD-1-mediated T-cell suppression but greater T-cell effector functions following blockade.

R. Rebhun, W. Murphy, B. Blazar, 2018 .

Autoimmune T cells lured to a FASL web of death by MSCs.

J. Nolta, W. Murphy, 2012, Cell stem cell.

Rejection of bone marrow cells by irradiated mice: NK and T cells recognize different antigens.

W. Murphy, C. Sentman, A. Mikhael, 1987, Transplantation proceedings.

The path(way) less traveled.

W. Murphy, M. Abedi, 2013, Blood.

Blood stem cell transplantation in older patients.

D. Longo, M. V. D. van den Brink, W. Murphy, 2009, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.