P. Garidel

发表

Transfection Efficiency and Cytotoxicity of Nonviral Gene Transfer Reagents in Human Smooth Muscle and Endothelial Cells

R. Peschka-Süss, Karin Kiefer, J. Clement, 2004, Pharmaceutical Research.

Stabilized Nonviral Formulations for the Delivery of MCP-1 Gene into Cells of the Vasculoendothelial System

M. Ogris, E. Wagner, J. Pelisek, 2004, Pharmaceutical Research.

Stabilization of IgG1 in spray-dried powders for inhalation.

P. Garidel, W. Friess, S. Schüle, 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Spectroscopic methods for assessing the molecular origins of macroscopic solution properties of highly concentrated liquid protein solutions.

P. Garidel, D. Hinderberger, M. Blech, 2018, Analytical biochemistry.

Peptide-based treatment of sepsis

K. Brandenburg, T. Gutsmann, P. Garidel, 2011, Applied Microbiology and Biotechnology.

Invited review: Mechanisms of endotoxin neutralization by synthetic cationic compounds

K. Brandenburg, T. Gutsmann, P. Garidel, 2006, Journal of endotoxin research.

Bacterial cell wall compounds as promising targets of antimicrobial agents I. Antimicrobial peptides and lipopolyamines.

M. Hornef, K. Brandenburg, T. Gutsmann, 2012, Current drug targets.

Process Development and Manufacturing of Therapeutic Antibodies

P. Garidel, H. Kaufmann, B. Enenkel, 2014 .

A critical evaluation of self-interaction chromatography as a predictive tool for the assessment of protein-protein interactions in protein formulation development: a case study of a therapeutic monoclonal antibody.

Patrick Garidel, Wolfgang Friess, P. Garidel, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The microstructure of the stratum corneum lipid barrier: mid-infrared spectroscopic studies of hydrated ceramide:palmitic acid:cholesterol model systems.

Patrick Garidel, P. Garidel, Andreas Kerth, 2010, Biophysical chemistry.

Complex Micellization Behavior of the Polysorbates Tween 20 and Tween 80.

Maximilian H. Ulbrich, H. Heerklotz, P. Garidel, 2021, Molecular pharmaceutics.

Improved Solution-State Properties of Monoclonal Antibodies by Targeted Mutations.

Lars V. Schäfer, Sebastian Kube, P. Garidel, 2017, The journal of physical chemistry. B.

The membrane-activity of Ibuprofen, Diclofenac, and Naproxen: a physico-chemical study with lecithin phospholipids.

K. Brandenburg, P. Garidel, M. Suwalsky, 2009, Biochimica et biophysica acta.

Non-Crystalline Systems

S. Blondelle, D. Svergun, M. Petoukhov, 2014 .

Adaption of human antibody λ and κ light chain architectures to CDR repertoires

F. Rousseau, Rob van der Kant, Joost Schymkowitz, 2019, Protein engineering, design & selection : PEDS.

Investigating Photodegradation of Antibodies Governed by the Light Dosage.

P. Garidel, M. Blech, J. Buske, 2021, International journal of pharmaceutics.

Taking subvisible particle quantitation to the limit: Uncertainties and statistical challenges with ophthalmic products for intravitreal injection.

A. Böhrer, P. Garidel, T. Menzen, 2019, Journal of pharmaceutical sciences.

Subvisible (2-100 μm) particle analysis during biotherapeutic drug product development: Part 2, experience with the application of subvisible particle analysis.

Tony Lubiniecki, M. Rossi, P. Garidel, 2015, Biologicals : journal of the International Association of Biological Standardization.

Subvisible (2-100 μm) Particle Analysis During Biotherapeutic Drug Product Development: Part 1, Considerations and Strategy.

Tony Lubiniecki, M. Rossi, P. Garidel, 2015, Journal of pharmaceutical sciences.

Resolving power of dynamic light scattering for protein and polystyrene nanoparticles

P. Garidel, Anne R. Karow, Jana Götzl, 2015, Pharmaceutical development and technology.

Development of Antimicrobial Peptides Based on Limulus Anti-Lipopolysaccharide Factor (LALF)

K. Wiesmüller, K. Brandenburg, T. Gutsmann, 2019, Endotoxin Detection and Control in Pharma, Limulus, and Mammalian Systems.

The expression of endotoxic activity in the Limulus test as compared to cytokine production in immune cells.

K. Brandenburg, P. Garidel, J. Howe, 2009, Current medicinal chemistry.

Galleria mellonella native and analogue peptides Gm1 and ΔGm1. II) anti-bacterial and anti-endotoxic effects.

C. Marella, K. Brandenburg, T. Gutsmann, 2014, Biochimica et biophysica acta.

Human cells and cell membrane molecular models are affected in vitro by the nonsteroidal anti-inflammatory drug ibuprofen.

P. Garidel, M. Suwalsky, A. Edwards, 2011, Biochimica et biophysica acta.

Lyophilization of High-Concentration Protein Formulations

P. Garidel, Ingo Presser, 2018, Methods in Pharmacology and Toxicology.

High‐concentration protein formulations: How high is high?

Lars V. Schäfer, P. Garidel, M. Blech, 2017, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Prediction of colloidal stability of high concentration protein formulations

A. Blume, P. Garidel, M. Wagner, 2015, Pharmaceutical development and technology.

Development and validation of a selective marker-based quantification of polysorbate 20 in biopharmaceutical formulations using UPLC QDa detection.

P. Garidel, J. Buske, Torsten Schultz-Fademrecht, 2020, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Polysorbate degradation in biotherapeutic formulations: Identification and discussion of current root causes

P. Garidel, M. Blech, Ingo Presser, 2018, International journal of pharmaceutics.

Surface tailored zein as a novel delivery system for hypericin: Application in photodynamic therapy.

U. Bakowsky, P. Garidel, Imran Tariq, 2021, Materials science & engineering. C, Materials for biological applications.

Hydrogel formulations for biologicals: current spotlight from a commercial perspective.

P. Garidel, L. Ickenstein, 2018, Therapeutic delivery.

Biophysical study of the non-steroidal anti-inflammatory drugs (NSAID) ibuprofen, naproxen and diclofenac with phosphatidylserine bilayer membranes.

K. Brandenburg, P. Garidel, M. Suwalsky, 2016, Biochimica et biophysica acta.

The application of STEP‐technology® for particle and protein dispersion detection studies in biopharmaceutical research

N. Herrmann, S. R. Pinnapireddy, U. Bakowsky, 2018, International journal of pharmaceutics.

Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity.

Lars V. Schäfer, M. Tully, Sebastian Kube, 2019, Biophysical journal.

Thermodynamics of Lipid Organization and Domain Formation in Phospholipid Bilayers

A. Blume, P. Garidel, C. Johann, 2000 .

Nanoparticle tracking analysis of particle size and concentration detection in suspensions of polymer and protein samples: Influence of experimental and data evaluation parameters.

J. Gross, U. Bakowsky, P. Garidel, 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Electrostatic interactions of alkaline earth cations with 1,2-dimyristoyl-sn-glycero-3-phosphatidic acid (DMPA) model membranes at neutral and acidic pH

A. Blume, P. Garidel, 2019, European Biophysics Journal.

Large-scale production of lipoplexes with long shelf-life.

R. Peschka-Süss, Karin Kiefer, J. Clement, 2005, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Packing characteristics of a model system mimicking cytoplasmic bacterial membranes.

P. Garidel, K. Lohner, G. Degovics, 2001, Chemistry and physics of lipids.

Nonideal mixing and phase separation in phosphatidylcholine-phosphatidic acid mixtures as a function of acyl chain length and pH.

A. Blume, P. Garidel, C. Johann, 1997, Biophysical journal.

Interaction of quorum signals with outer membrane lipids: insights into prokaryotic membrane vesicle formation

M. Roessle, L. Mashburn-Warren, K. Brandenburg, 2008, Molecular microbiology.

HP-β-CD for the formulation of IgG and Ig-based biotherapeutics.

P. Garidel, Helen Haixia Wu, Blech Michaela, 2021, International journal of pharmaceutics.

Cathelicidin and PMB neutralize endotoxins by multifactorial mechanisms including LPS interaction and targeting of host cell membranes

M. Brameshuber, G. Schütz, K. Brandenburg, 2021, Proceedings of the National Academy of Sciences.

Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain

Sebastian Kube, Simon Fischer, P. Garidel, 2020, mAbs.

Prediction and Reduction of the Aggregation of Monoclonal Antibodies

F. Rousseau, A. Gils, P. Schulz, 2017, Journal of molecular biology.

The mixing behavior of pseudobinary phosphatidylcholine-phosphatidylglycerol mixtures as a function of pH and chain length

A. Blume, P. Garidel, C. Johann, 1997, European Biophysics Journal.

Characterization of radicals in polysorbate 80 using electron paramagnetic resonance (EPR) spectroscopy and spin trapping

P. Garidel, K. Mäder, Judith J. Mittag, 2022, International journal of pharmaceutics: X.

Concentration Effects in the Interaction of Monoclonal Antibodies (mAbs) with their Immediate Environment Characterized by EPR Spectroscopy

P. Garidel, D. Hinderberger, M. Blech, 2019, Molecules.

Surface Tension and Self-association Properties of Aqueous Polysorbate 20 HP and 80 HP Solutions: Insights into Protein Stabilisation Mechanisms

A. Blume, P. Garidel, M. Blech, 2020, Journal of Pharmaceutical Innovation.

Solubilization of negatively charged DPPC/DPPG liposomes by bile salts.

R. Neubert, A. Blume, P. Garidel, 2004, Journal of colloid and interface science.

Structural organisation and phase behaviour of a stratum corneum lipid analogue: ceramide 3A.

P. Garidel, 2006, Physical chemistry chemical physics : PCCP.

Effective Antimicrobial and Anti-Endotoxin Activity of Cationic Peptides Based on Lactoferricin: A Biophysical and Microbiological Study

S. Blondelle, M. Roessle, K. Brandenburg, 2010 .

Conformational analysis of protein secondary structure during spray-drying of antibody/mannitol formulations.

P. Garidel, W. Friess, S. Schüle, 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide.

S. Blondelle, K. Brandenburg, P. Garidel, 2005, The Biochemical journal.

Physicochemical characterization and biological activity of lipooligosaccharides and lipid A from Neisseria meningitidis

M. Koch, B. Lindner, D. Stephens, 2007, Journal of endotoxin research.

Investigation into the interaction of recombinant human serum albumin with Re-lipopolysaccharide and lipid A

M. Koch, A. Blume, K. Brandenburg, 2002, Journal of endotoxin research.

Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations of Polysorbates

A. Lamprecht, P. Garidel, Maryam A. Shetab Boushehri, 2022, Pharmaceutics.

Physicochemical characterization of the endotoxins from Coxiella burnetii strain Priscilla in relation to their bioactivities

M. Koch, K. Brandenburg, P. Garidel, 2004, BMC Biochemistry.

Divalent cations affect chain mobility and aggregate structure of lipopolysaccharide from Salmonella minnesota reflected in a decrease of its biological activity.

K. Brandenburg, A. Schromm, P. Garidel, 2005, Biochimica et biophysica acta.

Structural and morphological investigations of the formation of quasi-crystalline phases of 1,2-dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG)

A. Blume, G. Rapp, P. Garidel, 2001 .

A Fourier transform infrared spectroscopic study of the interaction of alkaline earth cations with the negatively charged phospholipid 1, 2-dimyristoyl-sn-glycero-3-phosphoglycerol.

A. Blume, P. Garidel, W. Hübner, 2000, Biochimica et biophysica acta.

Investigation into the interaction of the bacterial protease OmpT with outer membrane lipids and biological activity of OmpT:lipopolysaccharide complexes

M. Egmond, A. Wiese, K. Brandenburg, 2005, European Biophysics Journal.

Insights into protein–polysorbate interactions analysed by means of isothermal titration and differential scanning calorimetry

A. Blume, P. Garidel, C. Hoffmann, 2009, European Biophysics Journal.

Miscibility of phosphatidylethanolamine-phosphatidylglycerol mixtures as a function of pH and acyl chain length

A. Blume, P. Garidel, 2000, European Biophysics Journal.

Morphology, size distribution, and aggregate structure of lipopolysaccharide and lipid A dispersions from enterobacterial origin

V. Vogel, W. Mäntele, M. Roessle, 2011, Innate immunity.

Physicochemical properties of microbial glycopolymers

K. Brandenburg, T. Gutsmann, P. Garidel, 2010 .

Phase diagrams of monoacylated amide-linked disaccharide glycolipids.

M. Roessle, K. Brandenburg, T. Gutsmann, 2009, Chemistry and physics of lipids.

Structural polymorphism of hydrated ether-linked dimyristyl maltoside and melibioside.

K. Brandenburg, T. Gutsmann, P. Garidel, 2008, Chemistry and physics of lipids.

What can calorimetry tell us about changes of three-dimensional aggregate structures of phospholipids and glycolipids?

M. Koch, K. Brandenburg, U. Seydel, 2006 .

Viscosity measurements of antibody solutions by photon correlation spectroscopy: an indirect approach – limitations and applicability for high-concentration liquid protein solutions

Patrick Garidel, A. Blume, P. Garidel, 2013, Pharmaceutical development and technology.

Buffer capacity of biologics—from buffer salts to buffering by antibodies

Patrick Garidel, P. Garidel, Anne R Karow, 2013, Biotechnology progress.

Self-Organisation, Thermotropic and Lyotropic Properties of Glycolipids Related to their Biological Implications

K. Brandenburg, P. Garidel, V. Vill, 2015, The open biochemistry journal.

Thermodynamic Characterization of Bile Salt Aggregation as a Function of Temperature and Ionic Strength Using Isothermal Titration Calorimetry

A. Blume, P. Garidel, A. Hildebrand, 2000 .

Albumin displacement at the air–water interface by Tween (Polysorbate) surfactants

A. Blume, P. Garidel, M. Rabe, 2020, European Biophysics Journal.

Physico-chemistry of Lipopolysaccharides

A. Schromm, T. Gutsmann, P. Garidel, 2019, Encyclopedia of Biophysics.

An infrared reflection-absorption spectroscopic (IRRAS) study of the interaction of lipid A and lipopolysaccharide Re with endotoxin-binding proteins.

A. Blume, K. Brandenburg, P. Garidel, 2009, Medicinal chemistry (Shariqah (United Arab Emirates)).

Structural polymorphism and endotoxic activity of synthetic phospholipid-like amphiphiles.

M. Koch, H. Heine, K. Brandenburg, 2004, Biochemistry.

Membranolytic activity of bile salts: influence of biological membrane properties and composition.

A. Blume, P. Garidel, A. Hildebrand, 2007, Molecules.

Thermodynamic properties of association colloids

P. Garidel, A. Hildebrand, 2005 .

Thermodynamics of demicellization of mixed micelles composed of sodium oleate and bile salts.

R. Neubert, A. Blume, P. Garidel, 2004, Langmuir : the ACS journal of surfaces and colloids.

Temperature dependence of the interaction of cholate and deoxycholate with fluid model membranes and their solubilization into mixed micelles

R. Neubert, A. Blume, P. Garidel, 2003 .

Chapter 3 - Lipid Model Membranes and Biomembranes

A. Blume, P. Garidel, 1999 .

Biophysical mechanisms of endotoxin neutralization by cationic amphiphilic peptides.

Walter Richter, Patrick Garidel, Manfred Rössle, 2011, Biophysical journal.

Thermodynamic Analysis of the Interaction of Lipopolysaccharides with Cationic Compounds

K. Brandenburg, P. Garidel, J. Howe, 2008 .

Mechanism of interaction of optimized Limulus-derived cyclic peptides with endotoxins: thermodynamic, biophysical and microbiological analysis.

K. Brandenburg, T. Gutsmann, P. Garidel, 2007, The Biochemical journal.

Biophysical characterization of the interaction of Limulus polyphemus endotoxin neutralizing protein with lipopolysaccharide.

K. Brandenburg, P. Garidel, R. Jerala, 2004, European journal of biochemistry.

Physicochemical properties of bacterial glycopolymers in relation to bioactivity.

K. Brandenburg, P. Garidel, Mareike Müller, 2003, Carbohydrate research.

Physicochemical Interaction Study of Non-Steroidal Anti-Inflammatory Drugs with Dimyristoylphosphatidylethanolamine Liposomes

K. Brandenburg, P. Garidel, M. Suwalsky, 2010 .

Photo-Oxidation of Therapeutic Protein Formulations: From Radical Formation to Analytical Techniques

P. Garidel, D. Hinderberger, M. Blech, 2021, Pharmaceutics.

Frontiers in Clinical Drug Research-Anti Infectives

J. Hauber, Xiaochen Bo, M. Hornef, 2017 .

Current Understanding of Polymyxin B Applications in Bacteraemia/ Sepsis Therapy Prevention: Clinical, Pharmaceutical, Structural and Mechanistic Aspects

K. Brandenburg, P. Garidel, Martin-Luther-Universität Halle-Wittenberg, 2009 .

Structural prerequisites for endotoxic activity in the Limulus test as compared to cytokine production in mononuclear cells

M. Koch, K. Fukase, U. Zähringer, 2010, Innate immunity.

Bile salt induced solubilization of synthetic phosphatidylcholine vesicles studied by isothermal titration calorimetry

R. Neubert, A. Blume, P. Garidel, 2002 .

Systematic investigation of the effect of lyophilizate collapse on pharmaceutically relevant proteins I: stability after freeze-drying.

G. Winter, P. Garidel, K Schersch, 2010, Journal of pharmaceutical sciences.

Liquid-liquid phase separation of a monoclonal antibody at low ionic strength: Influence of anion charge and concentration.

Patrick Garidel, A. Blume, P. Garidel, 2017, Biophysical chemistry.

Anti-Infective Polypeptides for Combating Bacterial and Viral Infections

J. Hauber, M. Hornef, K. Brandenburg, 2014 .

Protein photodegradation in the visible range? Insights into protein photooxidation with respect to protein concentration

P. Garidel, D. Hinderberger, M. Blech, 2022, International journal of pharmaceutics: X.

Hydrolytic polysorbate 20 degradation - Sensitive detection of free fatty acids in biopharmaceuticals via UPLC-QDa analytics with isolator column.

P. Garidel, J. Buske, Frank Hämmerling, 2021, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Mid-FTIR-Microspectroscopy of stratum corneum single cells and stratum corneum tissue

Patrick Garidel, P. Garidel, 2002 .

Calorimetric and spectroscopic investigations of phytosphingosine ceramide membrane organisation

P. Garidel, 2002 .

Synthesis, control of substitution pattern and phase transitions of 2,3-di-O-methylcellulose.

G. Wenz, P. Garidel, P. Mischnick, 2000, Carbohydrate research.

Non-ideal mixing and fluid–fluid immiscibility in phosphatidic acid–phosphatidylethanolamine mixed bilayers

A. Blume, P. Garidel, C. Johann, 2011, European Biophysics Journal.

Poloxamer 188 as Surfactant in Biological Formulations - An Alternative for Polysorbate 20/80?

P. Garidel, K. Mäder, J. Buske, 2022, International journal of pharmaceutics.

Systematic investigation of the effect of lyophilizate collapse on pharmaceutically relevant proteins III: collapse during storage at elevated temperatures.

G. Winter, P. Garidel, K Schersch, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Systematic investigation of the effect of lyophilizate collapse on pharmaceutically relevant proteins, part 2: stability during storage at elevated temperatures.

Patrick Garidel, Gerhard Winter, G. Winter, 2012, Journal of pharmaceutical sciences.

Inhibition of Lipopolysaccharide- and Lipoprotein-Induced Inflammation by Antitoxin Peptide Pep19-2.5

T. Goldmann, K. Brandenburg, T. Gutsmann, 2018, Front. Immunol..

Effects of the nonsteroidal anti-inflammatory drug naproxen on human erythrocytes and on cell membrane molecular models.

P. Garidel, M. Suwalsky, F. Villena, 2010, Biophysical chemistry.

An in-depth examination of fatty acid solubility limits in biotherapeutic protein formulations containing polysorbate 20 and polysorbate 80.

P. Garidel, K. Mäder, J. Buske, 2020, International journal of pharmaceutics.

An update on endotoxin neutralization strategies in Gram-negative bacterial infections

K. Brandenburg, A. Schromm, P. Garidel, 2020, Expert review of anti-infective therapy.

Strategies for the Assessment of Protein Aggregates in Pharmaceutical Biotech Product Development

Patrick Garidel, Wim Jiskoot, W. Jiskoot, 2010, Pharmaceutical Research.

Lipid-based nanoparticle formulations for small molecules and RNA drugs

P. Garidel, L. Ickenstein, 2019, Expert opinion on drug delivery.

Temperature dependence of the binding of endotoxins to the polycationic peptides polymyxin B and its nonapeptide.

M. Koch, K. Brandenburg, P. Garidel, 2005, Biophysical journal.

Toxicological and Safety Pharmacological Profiling of the Anti-Infective and Anti-Inflammatory Peptide Pep19-2.5

K. Brandenburg, T. Gutsmann, P. Garidel, 2022, Microorganisms.

Synthetic Anti-lipopolysaccharide Peptides (SALPs) as Effective Inhibitors of Pathogen-Associated Molecular Patterns (PAMPs).

M. Hornef, K. Brandenburg, T. Gutsmann, 2019, Advances in experimental medicine and biology.

Biophysical Mechanisms of the Neutralization of Endotoxins by Lipopolyamines

Patrick Garidel, Manfred Rössle, K. Brandenburg, 2013, The open biochemistry journal.

Proteasome impairment by α-synuclein

Jochen H Weishaupt, F. Gillardon, P. Garidel, 2017, PloS one.

A rapid, sensitive and economical assessment of monoclonal antibody conformational stability by intrinsic tryptophan fluorescence spectroscopy

P. Garidel, M. Weichel, S. Bassarab, 2008, Biotechnology journal.

Miscibility of phospholipids with identical headgroups and acyl chain lengths differing by two methylene units: effects of headgroup structure and headgroup charge.

A. Blume, P. Garidel, 1998, Biochimica et biophysica acta.

Mid infrared microspectroscopic mapping and imaging: A bio‐analytical tool for spatially and chemically resolved tissue characterization and evaluationof drug permeation within tissues

Matthias Boese, Patrick Garidel, M. Boese, 2007, Microscopy research and technique.

A thermodynamic analysis of the binding interaction between polysorbate 20 and 80 with human serum albumins and immunoglobulins: a contribution to understand colloidal protein stabilisation.

A. Blume, P. Garidel, C. Hoffmann, 2009, Biophysical chemistry.

Thermodynamic analysis of the lipopolysaccharide-dependent resistance of gram-negative bacteria against polymyxin B.

M. Koch, K. Brandenburg, T. Gutsmann, 2007, Biophysical journal.

Expanding the toolbox for predictive parameters describing antibody stability considering thermodynamic and kinetic determinants

P. Garidel, Nuska Tschammer, D. Hinderberger, 2021, Pharmaceutical Research.

Formulations d'anticorps et procédés correspondants

P. Garidel, M. Grundman, Andreas Langer, 2014 .

Biophysical characterization of the interaction of high-density lipoprotein (HDL) with endotoxins.

Buko Lindner, Patrick Garidel, A. Blume, 2002, European journal of biochemistry.

Single Particle Characterization of Iron-induced Pore-forming α-Synuclein Oligomers*

C. Ross, A. Giese, H. Kretzschmar, 2008, Journal of Biological Chemistry.

Structural investigations into the interaction of hemoglobin and part structures with bacterial endotoxins

M. Roessle, A. Ulmer, E. Rietschel, 2008, Innate immunity.

Buffer-free therapeutic antibody preparations provide a viable alternative to conventionally buffered solutions: from protein buffer capacity prediction to bioprocess applications.

Patrick Garidel, P. Garidel, Anne R Karow, 2015, Biotechnology journal.

Probing Thermal Stability of MAbs By Intrinsic Tryptophan Fluorescence A Practical Approach for Preformulation Development

P. Garidel, M. Weichel, S. Bassarab, 2008 .

Microscopic Methods for Particle Characterization in Protein Pharmaceuticals

P. Garidel, A. Herre, W. Kliche, 2012 .

Cross-linked Hemoglobin Converts Endotoxically Inactive Pentaacyl Endotoxins into a Physiologically Active Conformation*

M. Koch, A. Blume, J. Levin, 2003, Journal of Biological Chemistry.

Industry perspective on the use and characterization of polysorbates for biopharmaceutical products Part 2: Survey report on control strategy preparing for the future.

Jason A. Starkey, P. Garidel, M. Jahn, 2022, Journal of pharmaceutical sciences.

Assessing the polysorbate degradation fingerprints and kinetics of lipases - how the activity of polysorbate degrading hydrolases is influenced by the assay and assay conditions.

P. Garidel, K. Mäder, J. Buske, 2021, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

An Intercompany Perspective on Practical Experiences of Predicting, Optimizing and Analyzing High Concentration Biologic Therapeutic Formulations.

Brittney J. Mills, P. Garidel, Shubhadra N. Singh, 2022, Journal of pharmaceutical sciences.

Thermal and Chemical Unfolding of a Monoclonal IgG1 Antibody: Application of the Multistate Zimm-Bragg Theory

J. Seelig, P. Garidel, M. Blech, 2020, Biophysical journal.

Thermal and Chemical Unfolding of a recombinant monoclonal IgG1 antibody: Application of the Multi-State Zimm-Bragg Theory

J. Seelig, P. Garidel, M. Blech, 2019, bioRxiv.

1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG) monolayers: influence of temperature, pH, ionic strength and binding of alkaline earth cations.

A. Blume, P. Garidel, 2005, Chemistry and physics of lipids.

Interaction of alkaline earth cations with the negatively charged phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphoglycerol : A differential scanning and isothermal titration calorimetric study

A. Blume, P. Garidel, 1999 .

Boosting antibody developability through rational sequence optimization

Daniel Seeliger, Patrick Garidel, Michaela Blech, 2015, mAbs.

Particle Detection and Characterization for Biopharmaceutical Applications: Current Principles of Established and Alternative Techniques

Patrick Garidel, Michaela Blech, Julia Gross-Rother, 2020, Pharmaceutics.

Industry perspective on the use and characterization of polysorbates for biopharmaceutical products Part 1: Survey report on current state and common practices for handling and control of polysorbates.

Jason A. Starkey, P. Garidel, M. Jahn, 2022, Journal of pharmaceutical sciences.

Micro-Flow Imaging multi-instrument evaluation for sub-visible particle detection.

P. Garidel, M. Blech, A. Boehrer, 2023, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Protein Therapeutics and Aggregates Characterized By Photon Correlation Spectroscopy An Application for High-Concentration Liquid Formulations

P. Garidel, Fabian Kebbel, 2010 .

Oil-Immersion Flow Imaging Microscopy for Quantification and Morphological Characterization of Submicron Particles in Biopharmaceuticals

Sebastian M. Kuhn, P. Garidel, T. Menzen, 2021, The AAPS journal.

Oil-Immersion Flow Imaging Microscopy for Quantification and Morphological Characterization of Submicron Particles in Biopharmaceuticals

P. Garidel, T. Menzen, A. Hawe, 2021, The AAPS Journal.

Corrigendum to “The membrane-activity of Ibuprofen, Diclofenac, and Naproxen: A physico-chemical study with lecithin phospholipids” [Biochim. Biophys. Acta 1788 (2009) 1296–1303]

K. Brandenburg, P. Garidel, M. Suwalsky, 2011 .

Molecular basis for endotoxin neutralization by amphipathic peptides derived from the alpha-helical cationic core-region of NK-lysin.

K. Brandenburg, T. Gutsmann, P. Garidel, 2010, Biophysical chemistry.

Correlation of protein-protein interactions as assessed by affinity chromatography with colloidal protein stability: A case study with lysozyme

Patrick Garidel, Wolfgang Friess, P. Garidel, 2009, Pharmaceutical development and technology.

Existence of a Superior Polysorbate Fraction in Respect to Protein Stabilization and Particle Formation?

Tim Diederichs, S. Voss, P. Garidel, 2023, International journal of pharmaceutics.

Characterization of virus particles and submicron-sized particulate impurities in recombinant adeno-associated virus drug product.

P. Garidel, T. Menzen, A. Hawe, 2023, Journal of pharmaceutical sciences.

Mechanisms of endotoxin neutralization by synthetic cationic compounds.

K. Brandenburg, T. Gutsmann, P. Garidel, 2006 .

The calculation of heat capacity curves and phase diagrams based on regular solution theory

A. Blume, P. Garidel, C. Johann, 2005 .

1,2-Dimyristoyl-sn-glycero-3-phosphoglycerol (DMPG) divalent cation complexes: an X-ray scattering and freeze-fracture electron microscopy study.

A. Blume, G. Rapp, P. Garidel, 2000 .

Fourier-Transform Midinfrared Spectroscopy for Analysis and Screening of Liquid Protein Formulations Part 2 : Detailed Analysis and Applications

Patrick Garidel, P. Garidel, Heidrun Schott, 2006 .

Lysozyme‐lysozyme self‐interactions as assessed by the osmotic second virial coefficient: Impact for physical protein stabilization

P. Garidel, W. Friess, V. Le Brun, 2009, Biotechnology journal.

Characterizing protein-protein-interaction in high-concentration monoclonal antibody systems with the quartz crystal microbalance.

P. Garidel, D. Johannsmann, J. Hartl, 2017, Physical chemistry chemical physics : PCCP.

Dipolar Interactions and Protein Hydration in Highly Concentrated Antibody Formulations.

P. Garidel, D. Hinderberger, M. Blech, 2022, Molecular pharmaceutics.

Antimicrobial Preservatives for Protein and Peptide Formulations: An Overview

Richard J. Marhöfer, P. Selzer, P. Garidel, 2023, Pharmaceutics.

Surface Tension and Self-association Properties of Aqueous Polysorbate 20 HP and 80 HP Solutions: Insights into Protein Stabilisation Mechanisms

A. Blume, P. Garidel, M. Blech, 2020, Journal of Pharmaceutical Innovation.

Thermodynamic Unfolding and Aggregation Fingerprints of Monoclonal Antibodies Using Thermal Profiling

P. Garidel, D. Hinderberger, M. Blech, 2020, Pharmaceutical Research.

Laser Light Scattering‐Based Techniques Used for the Characterization of Protein Therapeutics

P. Garidel, Fabian Kebbel, J. D. Engelsman, 2012 .

Composition dependence of vesicle morphology and mixing properties in a bacterial model membrane system.

R. Dimova, G. Pabst, P. Garidel, 2005, Biochimica et biophysica acta.

The electrokinetic potential of therapeutic proteins and its modulation: Impact on protein stability

A. Blume, P. Garidel, K. Reiche, 2012 .

Galleria mellonella native and analogue peptides Gm1 and ΔGm1. I) biophysical characterization of the interaction mechanisms with bacterial model membranes.

K. Brandenburg, T. Gutsmann, P. Garidel, 2014, Biochimica et biophysica acta.

Backgrounded Membrane Imaging—A Valuable Alternative for Particle Detection of Biotherapeutics?

P. Garidel, M. Blech, M. Strebl, 2023, Journal of Pharmaceutical Innovation.

An Interlaboratory Comparison on the Characterization of a Sub-micrometer Polydisperse Particle Dispersion.

D. Grier, K. Benkstein, W. Jiskoot, 2021, Journal of pharmaceutical sciences.

Insights in the biochemical composition of skin as investigated by micro infrared spectroscopic imaging

P. Garidel, 2003 .

Comparative SAXS and DSC study on stratum corneum structural organization in an epidermal cell culture model (ROC): impact of cultivation time.

S. Funari, A. Fahr, P. Garidel, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Bacterial cell wall compounds as promising targets of antimicrobial agents II. Immunological and clinical aspects.

M. Hornef, K. Brandenburg, T. Gutsmann, 2012, Current Drug Targets.

Structural polymorphism of hydrated monoacylated maltose glycolipids.

M. Roessle, K. Brandenburg, P. Garidel, 2008, Chemistry and physics of lipids.

Fourier-Transform Midinfrared Spectroscopy for Analysis and Screening of Liquid Protein Formulations , Part 1 Understanding Infrared Spectroscopy of Proteins

P. Garidel, H. Schott, 2006 .

Phytosphingosine and Sphingosine Ceramide Headgroup Hydrogen Bonding: Structural Insights through Thermotropic Hydrogen/Deuterium Exchange

P. Garidel, B. Marković, A. Mendelsohn, 2001 .

Stability of buffer-free freeze-dried formulations: A feasibility study of a monoclonal antibody at high protein concentrations.

Patrick Garidel, P. Garidel, Sven Bahrenburg, 2015, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Oxidation of polysorbates – An underestimated degradation pathway?

Tim Diederichs, P. Garidel, K. Mäder, 2023, International journal of pharmaceutics: X.

Industrial Manufacturing of Plasmid-DNA Products for Gene Vaccination and Therapy

Jochen Urthaler, Hermann Schuchnigg, Patrick Garidel, 2012 .

Physicochemical characterization of the endotoxins from Coxiella burnetii strain Priscilla in relation to their bioactivities

M. Koch, K. Brandenburg, P. Garidel, 2004, BMC Biochemistry.

Atomic force microscopic investigations of the gel phase of phosphatidylcholines containing ω-cyclohexyl fatty acids

A. Blume, P. Garidel, G. Förster, 2000 .

Interaction of Melittin with Phospholipid- and Lipopolysaccharide- Containing Model Membranes

S. Funari, K. Brandenburg, T. Gutsmann, 2009 .

Viscosity Prediction of High-Concentration Antibody Solutions with Atomistic Simulations

Lars V. Schäfer, P. Garidel, M. Blech, 2023, bioRxiv.