A. Hasilik

S. Grässel, C. Isidoro, A. Hasilik, 1991, European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies.

Suppression of the 'uncovering' of mannose-6-phosphate residues in lysosomal enzymes in the presence of NH4Cl.

C. Isidoro, A. Hasilik, F. Baccino, 1990, European journal of biochemistry.

Association of the precursor of cathepsin D with coated membranes. Kinetics and carbohydrate processing.

K. von Figura, A. Hasilik, T. Marquardt, 1987, European journal of biochemistry.

46-kDa mannose 6-phosphate-specific receptor: purification, subunit composition, chemical modification.

K. von Figura, A. Hasilik, H. Meyer, 1987, Biological chemistry Hoppe-Seyler.

Sulfated oligosaccharides in human lysosomal enzymes.

W. Huttner, K. von Figura, A. Hasilik, 1987, Biochemical and biophysical research communications.

Synthesis and transport of lysosomal acid phosphatase in normal and I-cell fibroblasts.

K. von Figura, A. Hasilik, V. Gieselmann, 1985, The Journal of biological chemistry.

Antibody to mannose 6‐phosphate specific receptor induces receptor deficiency in human fibroblasts.

K. Figura, A. Hasilik, V. Gieselmann, 1984, The EMBO journal.

Deficiency of UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase in organs of I-cell patients.

K. von Figura, A. Waheed, A. Hasilik, 1982, Biochemical and biophysical research communications.

Immunoprecipitation of labeled antigens with Eupergit C1Z.

S. Grässel, A. Hasilik, A. Röling, 1989, Analytical biochemistry.

Genetic heterogeneity of steroid sulfatase deficiency revealed with cDNA for human steroid sulfatase.

K. von Figura, A. Hasilik, J. Conary, 1987, Biochemical and biophysical research communications.

High yield synthesis and characterization of phosphorylated recombinant human procathepsin D expressed in mammalian cells.

Bonnie F. Sloane, Carlo Follo, C. Isidoro, 2006, Protein expression and purification.

Identification of plasma membrane associated mature β‐hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts

A. Orlacchio, C. Emiliani, A. Hasilik, 2005, FEBS letters.

Synthesis and processing of alpha-galactosidase A in human fibroblasts. Evidence for different mutations in Fabry disease.

R. Desnick, K. von Figura, A. Hasilik, 1987, The Journal of biological chemistry.

Heterogeneity in late-onset metachromatic leukodystrophy. Effect of inhibitors of cysteine proteinases.

K. von Figura, E. Shaw, A. Hasilik, 1986, American journal of human genetics.

Sequential detection of antigens in Western blots with differently colored products.

K. von Figura, A. Hasilik, N. Theisen, 1986, Analytical biochemistry.

Comparison of biosynthesis and subcellular distribution of lysozyme and lysosomal enzymes in U937 monocytes.

K. von Figura, A. Hasilik, D. Gupta, 1985, Biochimica et biophysica acta.

Synthesis and stability of arylsulfatase A and B in fibroblasts from multiple sulfatase deficiency.

K. von Figura, A. Hasilik, F. Steckel, 1985, European journal of biochemistry.

Biosynthesis and maturation of alpha-N-acetylglucosaminidase in normal and Sanfilippo B-fibroblasts.

K. von Figura, A. Hasilik, J. V. D. van de Kamp, 1984, American journal of human genetics.

LYSOSOMAL STORAGE DISORDERS CAUSED BY INSTABILITY OF THE MISSING ENZYMES

K. Figura, A. Hasilik, F. Steckel, 1984 .

Genesis of lysosomal enzyme deficiencies

K. Figura, A. Hasilik, 1984 .

Two allelic forms of human arylsulfatase A with different numbers of asparagine-linked oligosaccharides.

K. von Figura, A. Waheed, A. Hasilik, 1983, American journal of human genetics.

Biosynthesis of acid α‐glucosidase in late‐onset forms of glycogenosis type II (Pompe's disease)

K. von Figura, A. Waheed, A. Hasilik, 1982 .

Enhanced breakdown of arylsulfatase A in multiple sulfatase deficiency.

K. von Figura, A. Waheed, A. Hasilik, 1982, European journal of biochemistry.

Impaired phosphorylation of lysosomal enzymes in fibroblasts of patients with mucolipidosis III.

K. von Figura, A. Waheed, A. Hasilik, 1982, European journal of biochemistry.

Recognition Marker in Lysosomal Enzymes: Presence of α-N-acetylglucosamine(1)phospho(6)mannose Diester Groups

K. Figura, A. Waheed, G. Strecker, 1981 .

Biosynthesis of lysosomal enzymes

A. Hasilik, 1980 .

Cathepsin D precursors in clathrin-coated organelles from human fibroblasts

K. von Figura, E. Schulze-Lohoff, A. Hasilik, 1985, The Journal of cell biology.

A replacement of the active-site aspartic acid residue 293 in mouse cathepsin D affects its intracellular stability, processing and transport in HEK-293 cells.

A. Hasilik, T. Braulke, S. Storch, 2003, The Biochemical journal.

Molecular forms of beta-hexosaminidase and cathepsin D in serum and urine of healthy subjects and patients with elevated activity of lysosomal enzymes.

K. von Figura, M. Zühlsdorf, A. Hasilik, 1983, The Biochemical journal.

Effects of differentiation-inducing agents on synthesis, maturation and secretion of cathepsin D in U937 and HL-60 cells.

K. von Figura, A. Hasilik, T. Braulke, 1987, Biological chemistry Hoppe-Seyler.

Oligosaccharides in Lysosomal Enzymes

K. Figura, A. Hasilik, 1981 .

Purified recombinant human prosaposin forms oligomers that bind procathepsin D and affect its autoactivation.

H. Grosch, A. Hasilik, K. Sandhoff, 2004, The Biochemical journal.

Brefeldin A prevents uncovering but not phosphorylation of the recognition marker in cathepsin D.

C. Isidoro, A. Hasilik, J. Radons, 1990, Biological chemistry Hoppe-Seyler.

Mannose 6-phosphate-specific receptor is a transmembrane protein with a C-terminal extension oriented towards the cytosol.

K. von Figura, A. Hasilik, V. Gieselmann, 1985, The Biochemical journal.

UGA is translated as cysteine in pheromone 3 of Euplotes octocarinatus.

A. Hasilik, F. Meyer, A. Engström, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Netherlands Society for Microbiology meeting at Rotterdam on 8 December 1971

W. A. Scheffers, A. H. Stouthamer, A. Hasilik, 2006, Antonie van Leeuwenhoek.

Targeting myeloperoxidase to azurophilic granules in HL‐60 cells

A. Hasilik, B. Schmidt, P. Lemansky, 2003, Journal of leukocyte biology.

Subcellular location of two enzymes involved in the synthesis of phosphorylated recognition markers in lysosomal enzymes.

K. von Figura, A. Waheed, A. Hasilik, 1981, The Journal of biological chemistry.

Inhibition of the Apparent Rate of Synthesis of the Vacuolar Glycoprotein Carboxypeptidase Y and Its Protein Antigen by Tunicamycin in Saccharomyces cerevisiae

A. Hasilik, W. Tanner, Andrej Hasilik, 1976, Antimicrobial Agents and Chemotherapy.

Inactivation of chitin synthase in Saccharomyces cerevisiae

A. Hasilik, 2004, Archives of Microbiology.

The effect of 4-bromobenzyl isothiocyanate on the redox state of nicotinamide-adenine dinucleotides in Candida albicans.

A. Hasilik, M. Livař, 1972, Chemico-biological interactions.

Compartmentation of the tryptophan-synthase-proteolyzing system in Saccharomyces cerevisiae.

H. Holzer, A. Hasilik, H. Müller, 1974, European journal of biochemistry.

Participation of the tryptophan synthase inactivating system from yeast in the activation of chitin synthase.

H. Holzer, A. Hasilik, 1973, Biochemical and biophysical research communications.

On the Biosynthesis of Carboxypeptidase Y (CY)

A. Hasilik, W. Tanner, 1979 .

Biosynthesis of carboxypeptidase Y in yeast. Evidence for a precursor form of the glycoprotein.

A. Hasilik, W. Tanner, 1976, Biochemical and biophysical research communications.

Cathepsin D and beta-hexosaminidase synthesized in the presence of 1-deoxynojirimycin accumulate in the endoplasmic reticulum.

K. von Figura, A. Hasilik, V. Gieselmann, 1984, The Journal of biological chemistry.

Lysosomal segregation of a mannose‐rich glycoprotein imparted by the prosequence of myeloperoxidase

C. Isidoro, A. Hasilik, N. Harth, 1998, Journal of cellular biochemistry.

Glycosylation-site-selective synthesis of N-acetyl-lactosamine repeats in bis-glycosylated human lysozyme.

M. Karas, U. Bahr, B. Schröder, 2000, The Biochemical journal.

Biosynthesis of glycosylated human lysozyme mutants.

A. Hasilik, N. Harth, M. Horst, 1991, The Journal of biological chemistry.

Phosphorylation of lysosomal enzymes in fibroblasts. Marked deficiency of N-acetylglucosamine-1-phosphotransferase in fibroblasts of patients with mucolipidosis III.

K. von Figura, A. Waheed, A. Hasilik, 1982, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

Possible pathways for lysosomal enzyme delivery

J. Slot, H. Geuze, K. von Figura, 1985, The Journal of cell biology.

Molecular characterisation of ‘transmembrane protein 192’ (TMEM192), a novel protein of the lysosomal membrane

P. Saftig, B. Schröder, A. Hasilik, 2010, Biological chemistry.

Identification of a Lysosomal Peptide Transport System Induced during Dendritic Cell Development*

R. Tampé, P. Brossart, A. Hasilik, 2007, Journal of Biological Chemistry.

Integral and Associated Lysosomal Membrane Proteins

M. Mann, B. Schröder, Cuiping Pan, 2007, Traffic.

Characterisation of lipofuscin‐like lysosomal inclusion bodies from human placenta

B. Schröder, H. Elsässer, A. Hasilik, 2007, FEBS letters.

Distribution and subcellular localization of a lysosome-associated protein in human genital organs

A. Hasilik, G. Aumüller, H. Renneberg, 1997, Cell and Tissue Research.

Molecular organization of the human cathepsin D gene.

H. Grosch, A. Hasilik, G. Mersmann, 1991, DNA and cell biology.

Human tartrate-inhibitable lysosomal acid phosphatase. Purification, characterization, biosynthesis and intracellular transport.

K. von Figura, A. Waheed, A. Hasilik, 1986, Acta biochimica Polonica.

Steroid sulfatase. Biosynthesis and processing in normal and mutant fibroblasts.

K. von Figura, A. Hasilik, J. Conary, 1986, European journal of biochemistry.

On the effects of weak bases and monensin on sorting and processing of lysosomal enzymes in human cells.

J. Slot, H. Geuze, K. von Figura, 1987, European journal of cell biology.

NCU-G1 is a highly glycosylated integral membrane protein of the lysosome.

B. Schröder, M. Damme, A. Hasilik, 2009, The Biochemical journal.

Intracellular trafficking of lysosomal proteins and lysosomes.

B. Schröder, A. Hasilik, C. Wrocklage, 2009, International journal of clinical pharmacology and therapeutics.

The Potential of P1 Site Alterations in Peptidomimetic Protease Inhibitors as Suggested by Virtual Screening and Explored by the Use of CC‐Coupling Reagents

G. Klebe, C. Sotriffer, A. Evers, 2006, ChemMedChem.

Immuno-electron microscopical demonstration of lysosomes in human blood platelets and megakaryocytes using anti-cathepsin D.

J. Sixma, K. von Figura, H. Geuze, 1985, Blood.

A protocol for combined delipidation and subfractionation of membrane proteins using organic solvents.

B. Schröder, A. Hasilik, 2006, Analytical biochemistry.

Processing and transport of lysosomal enzymes in human monocyte line U937.

K. von Figura, A. Hasilik, A. Schmidt, 1984, Hoppe-Seyler´s Zeitschrift für physiologische Chemie.

Biosynthesis and maturation of arylsulfatase B in normal and mutant cultured human fibroblasts.

K. von Figura, A. Hasilik, F. Steckel, 1983, The Journal of biological chemistry.

Multiple sulfatase deficiency: degradation of arylsulfatase A and B after endocytosis in fibroblasts.

K. von Figura, A. Hasilik, F. Steckel, 1985, European journal of biochemistry.

Elevated Levels Of Activities Of β-Hexosaminidase And α-Mannosidase In Human Immunodeficiency Virus-Infected Patients

A. Hasilik, J. Faulhaber, T. Kucharzik, 1995 .

Successful Expression of a Selenomethionyl Protein under Control of th e Temperature-Sensitive λ λ Repressor Require s Higher than Norma l Temperatur e

H. Grosch, A. Hasilik, 1998 .

PMN responses following use of 2 biodegradable GTR membranes.

A. Heinecke, A. Hasilik, D. Lange, 2001, Journal of clinical periodontology.

Cathepsin D expression is decreased in Alzheimer's disease fibroblasts

G. Bernardi, S. Sorbi, A. Orlacchio, 2008, Neurobiology of Aging.

Expression and maturation of human cathepsin D in baby-hamster kidney cells.

A. Hasilik, M. Horst, Andrej Hasilik, 1991, The Biochemical journal.

Carbohydrate mediated recognition of lysosomal enzymes by cell surface receptors

K. Figura, A. Waheed, A. Hasilik, 1983, Journal of Biosciences.

Carbohydrate-free carboxypeptidase Y is transferred into the lysosome-like yeast vacuole.

K. von Figura, A. Hasilik, A. Wiemken, 1982, Biochemical and biophysical research communications.

Perturbation of Growth and Metabolism in Candida albicans by 4-Bromobenzyl Isothiocyanate and Iodoacetate

A. Hasilik, 1973, Zeitschrift fur Naturforschung. Teil C: Biochemie, Biophysik, Biologie, Virologie.

Myeloperoxidase is synthesized as larger phosphorylated precursor.

R. L. Olsen, K. Figura, A. Hasilik, 1984, The EMBO journal.

Effects of antibiotics on the development and stability of mitochondrial enzymes in Saccharomyces cerevisiae.

A. Hasilik, C. Görts, 1972, European journal of biochemistry.

Synthesis and processing of arylsulfatase A in human skin fibroblasts.

K. von Figura, A. Waheed, A. Hasilik, 1982, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

Selective inactivity of TGF-beta/decorin complexes.

E. Schönherr, H. Kresse, A. Hasilik, 1994, FEBS letters.

Juvenile and adult metachromatic leukodystrophy: partial restoration of arylsulfatase A (cerebroside sulfatase) activity by inhibitors of thiol proteinases.

K. von Figura, A. Hasilik, F. Steckel, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Calcitriol enhances transcriptional activity of lysozyme and cathepsin D genes in U937 promonocytes.

A. Hasilik, M. Horst, B. Redecker, 1989, The Biochemical journal.

Synthesis and stability of steroid sulfatase in fibroblasts from multiple sulfatase deficiency.

K. von Figura, A. Hasilik, J. Conary, 1988, Biological chemistry Hoppe-Seyler.

Effect of monensin on intracellular transport and receptor-mediated endocytosis of lysosomal enzymes.

K. von Figura, A. Hasilik, R. Pohlmann, 1984, The Biochemical journal.

Neutral endopeptidase-24.11 (enkephalinase). Biosynthesis and localization in human fibroblasts.

K. von Figura, A. Hasilik, J. E. Zijderhand-Bleekemolen, 1987, The Biochemical journal.

Biosynthesis, targeting, and processing of lysosomal proteins: pulse-chase labeling and immune precipitation.

A. Hasilik, S. Pohl, 2015, Methods in cell biology.

Synthesis of phosphorylated oligosaccharides in lysozyme is enhanced by fusion to cathepsin D.

H. Kirschke, B. Wiederanders, A. Hasilik, 1993, The Journal of biological chemistry.

Differential segregation of human and hamster cathepsin D in transfected baby-hamster kidney cells.

C. Isidoro, A. Hasilik, M. Horst, 1991, The Biochemical journal.

Biosynthesis of acid alpha-glucosidase in late-onset forms of glycogenosis type II (Pompe's disease).

K. von Figura, A. Waheed, A. Hasilik, 1982, FEBS letters.

Pdcd4 inhibits growth of tumor cells by suppression of carbonic anhydrase type II

A. Hasilik, B. Lankat-Buttgereit, A. Knolle, 2004, Molecular and Cellular Endocrinology.

Distinctive inhibition of the lysosomal targeting of lysozyme and cathepsin D by drugs affecting pH gradients and protein kinase C.

H. Geuze, S. Grässel, A. Hasilik, 1994, The Biochemical journal.

Oligosaccharides in lysosomal enzymes. Distribution of high-mannose and complex oligosaccharides in cathepsin D and beta-hexosaminidase.

K. von Figura, A. Hasilik, 1981, European Journal of Biochemistry.

A mild form of mucolipidosis type III in four Baluch siblings

P. Benson, A. Hasilik, A. Fensom, 1993, Clinical genetics.

Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.

T. Reinheckel, P. Saftig, B. Schröder, 2011, The Biochemical journal.

Protection of proteolysis-prone recombinant proteins in baculovirus expression systems.

H. Grosch, A. Hasilik, 1998, BioTechniques.

Selective inactivity of TGF-fl / decorin complexes

H. Kresse, A. Hasilik, H. Hausser, 2001 .