X. Ji

发表

Acyl‐hydrazide derivatives of a xanthine carboxylic congener (XCC) as selective antagonists at human A2B adenosine receptors

K. Jacobson, Yong‐Chul Kim, J. Linden, 1999 .

Ring-Constrained (N)-methanocarba nucleosides as adenosine receptor agonists: independent 5'-uronamide and 2'-deoxy modifications.

K. Jacobson, X. Ji, V. Marquez, 2001, Bioorganic & medicinal chemistry letters.

[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.

K. Jacobson, J. Linden, X. Ji, 2001, Biochemical pharmacology.

Species differences in ligand affinity at central A3‐adenosine receptors

K. Jacobson, G. Stiles, X. Ji, 1994, Drug development research.

Structure-activity relationships of 4-(phenylethynyl)-6-phenyl-1,4-dihydropyridines as highly selective A3 adenosine receptor antagonists.

K. Jacobson, X. Ji, N. Melman, 1997, Journal of medicinal chemistry.

Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist.

K. Jacobson, T. K. Harden, X. Ji, 2002, Molecular pharmacology.

Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors.

K. Jacobson, J. Linden, X. Ji, 2000, Journal of medicinal chemistry.

2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.

K. Jacobson, G. Stiles, X. Ji, 1994, Journal of medicinal chemistry.

Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists.

X. Ji, N. Melman, B. Fischer, 1994, Journal of medicinal chemistry.

Characterization of human striatal A2-adenosine receptors using radioligand binding and photoaffinity labeling.

K. Jacobson, G. Stiles, X. Ji, 1992, Journal of receptor research.

Agonist derived molecular probes for A2 adenosine receptors

L. Pannell, K. Jacobson, G. Stiles, 1989, Journal of molecular recognition : JMR.

Structure-activity relationships of 1,3-dialkylxanthine derivatives at rat A3 adenosine receptors.

K. Jacobson, G. Stiles, X. Ji, 1994, Journal of medicinal chemistry.

Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists.

K. Jacobson, G. Stiles, Y. Karton, 1996, Journal of medicinal chemistry.

Trifunctional agents as a design strategy for tailoring ligand properties: irreversible inhibitors of A1 adenosine receptors.

K. Jacobson, G. Stiles, X. Ji, 1991, Bioconjugate chemistry.

2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists.

K. Jacobson, T. K. Harden, X. Ji, 2003, Journal of medicinal chemistry.

Synthesis and biological activity of N6-(p-sulfophenyl)alkyl and N6-sulfoalkyl derivatives of adenosine: water-soluble and peripherally selective adenosine agonists.

K. Jacobson, X. Ji, K. S. Lee, 1992, Journal of medicinal chemistry.

6-phenyl-1,4-dihydropyridine derivatives as potent and selective A3 adenosine receptor antagonists.

K. Jacobson, X. Ji, N. Melman, 1996, Journal of medicinal chemistry.

Derivatives of the triazoloquinazoline adenosine antagonist (CGS15943) are selective for the human A3 receptor subtype.

K. Jacobson, X. Ji, Y. C. Kim, 1996, Journal of medicinal chemistry.

Chemical modification and irreversible inhibition of striatal A2a adenosine receptors.

K. Jacobson, G. Stiles, X. Ji, 1992, Molecular pharmacology.

Structure–Activity Relationships of 1,3-Dialkylxanthine Derivatives at Rat A 3 Adenosine Receptors

Jacobson, G. Stiles, X. Ji, 2018 .

Pyran template approach to the design of novel A3 adenosine receptor antagonists

K. Jacobson, X. Ji, N. Melman, 1999, Drug development research.

A SURVEY OF NONXANTHINE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS.

K. Jacobson, G. Stiles, J. Daly, 1996, Nucleosides & nucleotides.

"Cleavable trifunctional" approach to receptor affinity labeling: chemical regeneration of binding to A1-adenosine receptors.

K. Jacobson, X. Ji, B. Fischer, 1995, Bioconjugate chemistry.

8‐(3‐Isothiocyanatostyryl)caffeine is a selective, irreversible inhibitor of striatal A2‐Adenosine receptors

K. Jacobson, X. Ji, C. Gallo-Rodriguez, 1993, Drug development research.

Molecular recognition in adenosine receptors

K. Jacobson, X. Ji, S. Siddiqi, 1996 .

Functionalized congeners of 1,4-dihydropyridines as antagonist molecular probes for A3 adenosine receptors.

K. Jacobson, X. Ji, N. Melman, 1999, Bioconjugate chemistry.

Solubilized rabbit striatal A2a-adenosine receptors: stability and antagonist binding.

K. Jacobson, X. Ji, 1993, Archives of biochemistry and biophysics.

RIBOSE MODIFIED NUCLEOSIDES AND NUCLEOTIDES AS LIGANDS FOR PURINE RECEPTORS

S. Moro, K. Jacobson, X. Ji, 2001, Nucleosides, nucleotides & nucleic acids.

Stable isotope-labeled tryptophan as a precursor for studying the disposition of quinolinic acid in rabbits.

S. Markey, J. Yergey, M. Heyes, 1991, Advances in experimental medicine and biology.

Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists.

K. Jacobson, G. Stiles, Y. Karton, 1996, Journal of medicinal chemistry.

Synthesis and structure‐activity relationships of pyridoxal‐6‐arylazo‐5′‐phosphate and phosphonate derivatives as P2 receptor antagonists

G. Burnstock, K. Jacobson, T. K. Harden, 1998, Drug development research.

Non-competitive inhibition of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3-hydroxyanthranilic acid in whole brain of rat.

M. Heyes, X. Ji, M. Nishimura, 1991, Advances in Experimental Medicine and Biology.

Interactions of flavonoids and other phytochemicals with adenosine receptors.

K. Jacobson, X. Ji, N. Melman, 1996, Journal of Medicinal Chemistry.

Synthesis, CoMFA analysis, and receptor docking of 3,5-diacyl-2, 4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists.

S. Moro, K. Jacobson, X. Ji, 1999, Journal of medicinal chemistry.

Quinazolines as adenosine receptor antagonists: SAR and selectivity for A2B receptors.

K. Jacobson, J. Linden, X. Ji, 2003, Bioorganic & medicinal chemistry.

Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.

K. Jacobson, G. Cristalli, X. Ji, 1995, Journal of medicinal chemistry.

2-Substitution of A@-Benzyladenosine- W-uronamides Enhances Selectivity for & Adenosine Receptors

K. Jacobson, G. Stiles, X. Ji, 1994 .

Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists.

K. Jacobson, X. Ji, N. Melman, 2000, Journal of medicinal chemistry.

Synthesis and purine receptor affinity of 6-oxopurine nucleosides and nucleotides containing (N)-methanocarba-pseudoribose rings.

K. Jacobson, X. Ji, V. Marquez, 2001, Bioorganic & medicinal chemistry letters.

Novel N6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A3 adenosine receptors.

G. Spalluto, K. Jacobson, B. Cacciari, 1996, Journal of medicinal chemistry.

Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors.

K. Jacobson, G. Stiles, X. Ji, 1995, Journal of medicinal chemistry.

Selective ligands for rat A3 adenosine receptors: structure-activity relationships of 1,3-dialkylxanthine 7-riboside derivatives.

K. Jacobson, G. Stiles, X. Ji, 1994, Journal of medicinal chemistry.

Novel N6‐(Substituted‐phenylcarbamoyl)adenosine‐5′‐uronamides as Potent Agonists for A3 Adenosine Receptors.

G. Spalluto, K. Jacobson, B. Cacciari, 1996 .

Use of the triazolotriazine [3H]ZM 241385 as a radioligand at recombinant human A2B adenosine receptors.

K. Jacobson, X. Ji, 1999, Drug design and discovery.

3D-QSAR-Based Molecular Design to Discover Ultrahigh Active N-Phenylpyrazoles as Insecticide Candidates.

Li-xia Xiong, Zhengming Li, X. Ji, 2023, Journal of agricultural and food chemistry.

Design and optimization of novel 4-(2-fluorophenoxy)quinoline derivatives bearing a hydrazone moiety as c-Met kinase inhibitors.

X. Ji, Tiemin Sun, P. Gong, 2014, European journal of medicinal chemistry.

Adenosine receptor prodrugs: synthesis and biological activity of derivatives of potent, A1-selective agonists.

K. Jacobson, R. Bartus, X. Ji, 1994, Journal of pharmaceutical sciences.

Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists.

S. Moro, K. Jacobson, X. Ji, 1998, Journal of medicinal chemistry.

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists

K. Jacobson, G. Stiles, Yong‐Chul Kim, 1997, Neuropharmacology.

Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies.

J. Błaszczyk, G. Shi, X. Ji, 2001, Journal of medicinal chemistry.

[3H]XAC (xanthine amine congener) is a radioligand for A2-adenosine receptors in rabbit striatum

K. Jacobson, G. Stiles, X. Ji, 1991, Neurochemistry International.

Riboflavin: Inhibitory effects on receptors, G‐proteins, and adenylate cyclase

K. Jacobson, D. Shi, J. Daly, 1997, Drug development research.

Molecular recognition in P2 receptors: ligand development aided by molecular modeling and mutagenesis.

G. Burnstock, S. Moro, K. Jacobson, 1999, Progress in brain research.

Synthesis and adenosine receptor affinity of 7-beta-D-ribofuranosylxanthine.

K. Jacobson, X. Ji, N. Melman, 1998, Nucleosides & nucleotides.

Adenosine A3 receptor agonist‐induced neurotoxicity in rat cerebellar granule neurons

K. Jacobson, X. Ji, Y. Sei, 1997 .

Interactions of flavones and other phytochemicals with adenosine receptors.

Kenneth A Jacobson, S. Moro, K. Jacobson, 2002, Advances in experimental medicine and biology.

Synthesis and biological activity of a new series of N6-arylcarbamoyl, 2-(Ar)alkynyl-N6-arylcarbamoyl, and N6-carboxamido derivatives of adenosine-5'-N-ethyluronamide as A1 and A3 adenosine receptor agonists.

G. Spalluto, K. Jacobson, B. Cacciari, 1998, Journal of medicinal chemistry.

The utilization of a unified pharmacophore query in the discovery of new antagonists of the adenosine receptor family.

K. Jacobson, X. Ji, N. Melman, 2000, Bioorganic & medicinal chemistry letters.

Selective A(3) adenosine receptor antagonists: water-soluble 3, 5-diacyl-1,2,4-trialkylpyridinium salts and their oxidative generation from dihydropyridine precursors.

K. Jacobson, G. Stiles, X. Ji, 1999, Journal of medicinal chemistry.

A selective agonist affinity label for A3 adenosine receptors.

K. Jacobson, X. Ji, C. Gallo-Rodriguez, 1994, Biochemical and biophysical research communications.

Molecular characterization of A1 and A2a adenosine receptors

K. Jacobson, G. Stiles, X. Ji, 1993 .

Chronic administration of selective adenosine A1 receptor agonist or antagonist in cerebral ischemia.

K. Jacobson, R. Lin, X. Ji, 1994, European journal of pharmacology.

Derivatives of the Triazoloquinazoline Adenosine Antagonist (CGS15943) (I) are Selective for the Human A3 Receptor Subtype.

K. Jacobson, X. Ji, Y.-C. Kim, 1997 .

Fluorosulfonyl- and bis-(beta-chloroethyl)amino-phenylamino functionalized pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives: irreversible antagonists at the human A3 adenosine receptor and molecular modeling studies.

S. Moro, G. Spalluto, K. Jacobson, 2001, Journal of medicinal chemistry.