B. Schimmer

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A Role for Guanyl Nucleotide-Binding Regulatory Protein β- andγ -Subunits in the Expression of the Adrenocorticotropin Receptor

R. Qiu, C. Frigeri, B. Schimmer, 1998 .

Adrenocorticotropin‐resistant mutants of the Y1 adrenal cell line fail to express the adrenocorticotropin receptor

R. Qiu, B. Schimmer, W. K. Kwan, 1995, Journal of cellular physiology.

The causal relationship between mutations in cAMP-dependent protein kinase and the loss of adrenocorticotropin-regulated adrenocortical functions.

B. Schimmer, M. Wong, A. Królczyk, 1992, Molecular endocrinology.

Inhibitory Properties of the Regulatory Domains of Human Protein Kinase Cα and Mouse Protein Kinase Cε*

B. Schimmer, A. Parissenti, A. F. Kirwan, 1998, The Journal of Biological Chemistry.

Molecular strategies for the dominant inhibition of protein kinase C.

B. Schimmer, A. Parissenti, A. F. Kirwan, 1996, Endocrine research.

Steroidogenic factor 1: an essential mediator of endocrine development.

N. Hanley, Liping Zhao, C. Frigeri, 2002, Recent progress in hormone research.

The 1994 Upjohn Award Lecture. Molecular and genetic approaches to the study of signal transduction in the adrenal cortex.

B. Schimmer, 1995, Canadian journal of physiology and pharmacology.

Altered G protein activity in a desensitization-resistant mutant of the Y1 adrenocortical tumor cell line.

J. Mitchell, B. Schimmer, W. K. Kwan, 1998, Endocrinology.

ACTH-receptor deficient mutants of the Y1 mouse adrenocortical tumor cell line.

R. Qiu, B. Schimmer, W. K. Kwan, 1995, Endocrine research.

Site of action of adrenocorticotropic hormone (ACTH) in adrenal cell cultures.

B. Schimmer, G. Sato, K. Ueda, 1968, Biochemical and biophysical research communications.

The roles of cAMP and cAMP-dependent protein kinase in the expression of cholesterol side chain cleavage and steroid 11 beta-hydroxylase genes in mouse adrenocortical tumor cells.

B. Schimmer, K. Parker, D. Rice, 1989, The Journal of biological chemistry.

Multiple regulatory elements determine adrenocortical expression of steroid 21-hydroxylase.

B. Schimmer, K. Parker, D. Rice, 1990, The Journal of biological chemistry.

Analysis of the promoter region of the gene encoding mouse cholesterol side-chain cleavage enzyme.

M. S. Kirkman, B. Schimmer, K. Parker, 1990, The Journal of biological chemistry.

An enhancer element and a functional cyclic AMP-dependent protein kinase are required for expression of adrenocortical 21-hydroxylase.

J. Seidman, M. Szyf, B. Schimmer, 1988, The Journal of biological chemistry.

Recovery of responsiveness to ACTH and cAMP in a protein kinase-defective adrenal cell mutant following transfection with a protein kinase gene.

B. Schimmer, M. Wong, 1989, Endocrine research.

cis modification of the steroid 21-hydroxylase gene prevents its expression in the Y1 mouse adrenocortical tumor cell line.

J. Seidman, M. Szyf, B. Schimmer, 1990, Molecular endocrinology.

Promoter elements of the mouse 21-hydroxylase (Cyp-21) gene involved in cell-selective and cAMP-dependent gene expression

B. Schimmer, K. Parker, 1992, The Journal of Steroid Biochemistry and Molecular Biology.

Nucleotide-sequence-specific de novo methylation in a somatic murine cell line.

J. Seidman, M. Szyf, B. Schimmer, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Recovery of hormonal regulation in protein kinase defective adrenal cells through DNA‐mediated gene transfer

B. Schimmer, M. Wong, Donalee O’Brien, 1986, Journal of cellular physiology.

Altered cyclic AMP‐dependent protein kinase activity in a mutant adrenocortical tumor cell line

B. Schimmer, N. S. Gutmann, P. A. Rae, 1978, Journal of cellular physiology.

Adrenocortical cell lines

B. Schimmer, W. Rainey, Karla J. Saner, 2004, Molecular and Cellular Endocrinology.

Agonist-induced desensitization of adenylyl cyclase in Y1 adrenocortical tumor cells.

M. Olson, B. Schimmer, J. Tsao, 1991, Endocrine research.

Unmasking a Growth-promoting Effect of the Adrenocorticotropic Hormone in Y1 Mouse Adrenocortical Tumor Cells*

C. Lotfi, B. Schimmer, H. Armelin, 1997, The Journal of Biological Chemistry.

Mutations in cyclic AMP-dependent protein kinase and corticotropin (ACTH)-sensitive adenylate cyclase affect adrenal steroidogenesis.

B. Schimmer, J. Tsao, N. S. Gutmann, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Expression of murine 21-hydroxylase in mouse adrenal glands and in transfected Y1 adrenocortical tumor cells.

J. Seidman, J. Smith, D. Chaplin, 1985, Proceedings of the National Academy of Sciences of the United States of America.

The regulation of MAPKs in Y1 mouse adrenocortical tumor cells.

B. Schimmer, T. Le, 2001, Endocrinology.

Decreased levels of guanyl nucleotide-binding regulatory protein alpha-subunits in Y1 adrenocortical tumor cell mutants resistant to forskolin.

B. Schimmer, J. Tsao, 1990, Molecular endocrinology.

Regulation of adenylyl cyclase activity by beta-adrenergic agonists in a desensitization-resistant mutant cell line.

M. Olson, B. Schimmer, J. Tsao, 1991, Molecular endocrinology.

Minireview: transcriptional regulation of adrenocortical development.

G. Hammer, B. Schimmer, K. Parker, 2005, Endocrinology.

Molecular analysis of 21-hydroxylase gene expression in mouse adrenal cells.

J. Seidman, D. Chaplin, B. Schimmer, 1986, Endocrine research.

Structural and functional analysis of the promoter region of the gene encoding mouse steroid 11β-hydroxylase

P. White, S. Chua, B. Schimmer, 1989 .

Human pancreatic islet tumor cells maintained in vitro

B. Schimmer, C. Yip, 1973, Diabetologia.

UDP-galactose:Glycoprotein galactosyltransferase activity in a clonal line of rat glial tumor cells and in rat brain

B. Schimmer, S. Mookerjea, 1975 .

Phenotypically variant adrenal tumor cell cultures with biochemical lesions in the ACTH‐stimulated steroidogenic pathway

B. Schimmer, 1969, Journal of cellular physiology.

Genetics of the Development and Function of the Adrenal Cortex

B. Schimmer, K. Parker, 2001, Reviews in Endocrine and Metabolic Disorders.

Cyclic nucleotides in hormonal regulation of adrenocortical function.

B. Schimmer, 1980, Advances in cyclic nucleotide research.

Analysis of the mutation to forskolin-resistance in Y1 adrenocortical tumor cells.

B. Schimmer, J. Tsao, M. Wong, 1984, Endocrine research.

Gene interactions in gonadal development.

A. Schedl, B. Schimmer, K. Parker, 1999, Annual review of physiology.

Forskolin-resistant Y1 mutants harbor defects associated with the guanyl nucleotide-binding regulatory protein, Gs.

L. Endrenyi, B. Schimmer, J. Tsao, 1987, The Journal of biological chemistry.

The identity of neoxanthin and foliaxanthin

B. Weedon, N. Krinsky, C. Chichester, 1967 .

The structure of neoxanthin and the trollein-like carotenoid from Euglena gracilis.

N. Krinsky, B. Schimmer, 1966, Biochemistry.

Minireview: steroidogenic factor 1: its roles in differentiation, development, and disease.

P. White, B. Schimmer, 2010, Molecular endocrinology.

Steroidogenic factor 1: a key determinant of endocrine development and function.

B. Schimmer, K. Parker, 1997, Endocrine reviews.

Clonal variation in adrenocorticotropin-induced desensitization of adenylate cyclase in Y1 adrenocortical tumor cells. Association with a 68,000-dalton protein.

B. Schimmer, V. M. Watt, 1982, The Journal of biological chemistry.

Isolation of mutant adrenocortical tumor cells resistant to cyclic nucleotides

B. Schimmer, J. Tsao, M. Knapp, 1977, Molecular and Cellular Endocrinology.

Genes essential for early events in gonadal development

B. Schimmer, K. Parker, 2002, EXS.

Steroidogenic factor 1 plays multiple roles in endocrine development and function.

A. Swain, B. Schimmer, K. Caron, 1997, Recent progress in hormone research.

Fifteenth conference on the adrenal cortex (adrenal 2012) League City, Texas June 19–22, 2012

B. Schimmer, 2013, Molecular and Cellular Endocrinology.

Genes essential for early events in gonadal development

A. Schedl, B. Schimmer, K. Parker, 1999, Cellular and Molecular Life Sciences CMLS.

Effects of mutating different steroidogenic factor-1 protein regions on gene regulation

J. Xue, B. Schimmer, D. Lopez, 2001, Endocrine.

Impaired steroidogenic factor 1 (NR5A1) activity in mutant Y1 mouse adrenocortical tumor cells.

C. Frigeri, B. Schimmer, J. Tsao, 2000, Molecular endocrinology.

Identification of Promoter Elements in the Mouse 2%Hydroxylase (Cyp21) Gene that Require a Functional Cyclic Adenosine

B. Schimmer, K. Parker, A. Parissenti, 1993 .

Heterologous desensitization of the human dopamine D1 receptor in Y1 adrenal cells and in a desensitization-resistant Y1 mutant.

M. Olson, B. Schimmer, 1992, Molecular endocrinology.

The roles of cAMP and cAMP-dependent protein kinase in the regulation of adrenocortical functions: analysis using DNA-mediated gene transfer.

B. Schimmer, M. Wong, D. O’Brien, 1986, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Molecular basis for the 3',5'-cyclic adenosine monophosphate resistance of Kin mutant Y1 adrenocortical tumor cells.

M. Olson, B. Schimmer, A. Królczyk, 1993, Molecular endocrinology.

Adrenocortical Y1 cells.

B. Schimmer, 1979, Methods in enzymology.

Transcriptional regulation of the genes encoding the cytochrome P-450 steroid hydroxylases.

B. Schimmer, K. Parker, 1995, Vitamins and hormones.

Regulation of 21-hydroxylase gene expression.

M. Szyf, B. Schimmer, K. Parker, 1989, Endocrine research.

Identification of promoter elements in the mouse 21-hydroxylase (Cyp21) gene that require a functional cyclic adenosine 3',5'-monophosphate-dependent protein kinase.

B. Schimmer, K. Parker, A. Parissenti, 1993, Molecular endocrinology.

A cAMP-responsive element regulates expression of the mouse steroid 11 beta-hydroxylase gene.

B. Schimmer, K. Parker, D. Rice, 1989, The Journal of biological chemistry.

Characterization of a regulatory region of the steroid 21-hydroxylase gene.

J. Seidman, D. Chaplin, B. Schimmer, 1986, The Journal of biological chemistry.

Transcriptional regulation of the adrenal steroidogenic enzymes

B. Schimmer, K. Parker, 1993, Trends in Endocrinology & Metabolism.

Corticotropin (ACTH) regulates alternative RNA splicing in y1 mouse adrenocortical tumor cells☆

M. Cordova, B. Schimmer, 2015, Molecular and Cellular Endocrinology.

Global profiles of gene expression induced by adrenocorticotropin in Y1 mouse adrenal cells.

Q. Morris, A. Goryachev, A. Schimmer, 2006, Endocrinology.

Sixteenth Conference on the Adrenal Cortex (Adrenal 2014), Chicago, Illinois, June 17–20, 2014

B. Schimmer, 2015, Molecular and Cellular Endocrinology.

Contributions of steroidogenic factor 1 to the transcription landscape of Y1 mouse adrenocortical tumor cells

Q. Morris, S. Mostafavi, J. Scheys, 2011, Molecular and Cellular Endocrinology.

Contributions of specificity protein-1 and steroidogenic factor 1 to Adcy4 expression in Y1 mouse adrenal cells.

J. Scheys, G. Hammer, B. Schimmer, 2008, Endocrinology.

A genome-wide assessment of adrenocorticotropin action in the Y1 mouse adrenal tumor cell line

Q. Morris, M. Cordova, B. Schimmer, 2007, Molecular and Cellular Endocrinology.

Expression of adenylyl cyclase-4 (AC-4) in Y1 and forskolin-resistant adrenal cells

P. Albert, B. Schimmer, J. Tsao, 2004, Molecular and Cellular Endocrinology.

SF1 POLYMORPHISMS IN THE MOUSE AND STEROIDOGENIC POTENTIAL

M. Cordova, C. Frigeri, B. Schimmer, 2002, Endocrine research.

The Activation Function of Steroidogenic Factor-1 is Impaired in Acth-Resistant Y1 Mutants

C. Frigeri, B. Schimmer, 2000, Endocrine research.

Identification and characterization of two upstream elements that regulate adrenocortical expression of steroid 11β-hydroxylase

B. Schimmer, K. Parker, D. Rice, 1990 .

Isolation of forskolin-resistant adrenal cells defective in the adenylate cyclase system.

B. Schimmer, J. Tsao, 1984, The Journal of biological chemistry.

mRNA from mutant Y1 adrenal cells directs the synthesis of altered regulatory subunits of type 1 cAMP-dependent protein kinase.

S. Williams, B. Schimmer, 1983, The Journal of biological chemistry.

Alteration of the regulatory subunit of type 1 cAMP-dependent protein kinase in mutant Y1 adrenal cells resistant to 8-bromoadenosine 3':5'-monophosphate.

M. Mumby, J. Beavo, B. Schimmer, 1982, The Journal of biological chemistry.

Association of a 68,000-dalton protein with adrenocorticotropin-sensitive adenylate cyclase activity in Y1 adrenocortical tumor cells.

B. Schimmer, V. M. Watt, 1981, The Journal of biological chemistry.

Adenylate cyclase activity and steroidogenesis in phenotypic revertants of an ACTH-insensitive adrenal tumour cell line

B. Schimmer, 1976, Nature.

Iodinated derivatives of adrenocorticotropic hormone. Preparation of iodinated alpha 1-24-ACTH with full hormonal activity.

B. Schimmer, P. A. Rae, 1974, The Journal of biological chemistry.

Adenylate cyclase activity in adrenocorticotropic hormone-sensitive and mutant adrenocortical tumor cell lines.

B. Schimmer, 1972, The Journal of biological chemistry.

CHAPTER 8 – Embryology and Genetics of the Mammalian Gonads and Ducts

B. Schimmer, K. Parker, 2006 .

Genes essential for early events in gonadal

B. Schimmer, developmenth L Parker, 2002 .

Genes essential for early events in gonadal development.

A. Schedl, B. Schimmer, K. Parker, 2002, Cellular and molecular life sciences : CMLS.

Steroidogenic Factor 1

B. Schimmer, K. Parker, 2002, Definitions.

Ahch and the feminine mystique

B. Schimmer, K. Parker, 1998, Nature Genetics.

Influence of lithium ions on epinephrine-stimulated adenylate cyclase activity in cultured glial tumor cells.

B. Schimmer, 1973, Biochimica et biophysica acta.

The roles of the nuclear receptor steroidogenic factor 1 in endocrine differentiation and development

B. Schimmer, K. Parker, 1996, Trends in Endocrinology & Metabolism.

Regulation of ornithine decarboxylase activity by corticotropin in adrenocortical tumor cell clones: roles of cyclic AMP and cyclic AMP-dependent protein kinase.

B. Schimmer, G. Burrow, N. S. Gutmann, 1980, Proceedings of the National Academy of Sciences of the United States of America.

A polymorphic form of steroidogenic factor-1 is associated with adrenocorticotropin resistance in y1 mouse adrenocortical tumor cell mutants.

M. Cordova, C. Frigeri, B. Schimmer, 2002, Endocrinology.

Amplification of the Transketolase Gene in Desensitization-resistant Mutant Y1 Mouse Adrenocortical Tumor Cells (*)

B. Schimmer, J. Tsao, W. Czerwinski, 1996, The Journal of Biological Chemistry.

Characterization of the cDNA corresponding to a phosphoprotein (p43) intermediary in the action of ACTH.

L. Dada, B. Schimmer, C. Paz, 1996, Endocrine research.

Isolation of ACTH-resistant Y1 adrenal tumor cells.

B. Schimmer, 1985, Methods in Enzymology.

Forskolin-resistant Y1 adrenal cell mutants are deficient in adenylyl cyclase type 4

P. Albert, B. Schimmer, J. Tsao, 2004, Molecular and Cellular Endocrinology.

Responses of Y1 adrenocortical tumor cells to o-nitrophenyl sulfenyl ACTH

B. Schimmer, J. Ramachandran, P. A. Rae, 1980, Molecular and Cellular Endocrinology.

cDNA for the beta 1 subunit of guanyl nucleotide-binding regulatory proteins from mouse adrenal glands.

R. Qiu, B. Schimmer, 1996, Gene.

To Endocrinology : The Hypothalamic-Pituitary Axis

B. Schimmer, K. Parker, 2016 .

Expression of a mutant regulatory subunit of cAMP-dependent protein kinase in the Caco-2 human colonic carcinoma cell line.

M. Buchwald, B. Schimmer, W. Auerbach, 1992, Biochemistry and cell biology = Biochimie et biologie cellulaire.

The Fourteenth Adrenal Cortex Conference (Adrenal 2010) and Keith L. Parker Memorial Symposium

B. Schimmer, 2011, Molecular and Cellular Endocrinology.

Reduced mRNA levels for the multidrug‐resistance genes in cAMP‐dependent protein kinase mutant cell lines

I. Pastan, M. Gottesman, B. Schimmer, 1992, Journal of cellular physiology.

Seventeenth Conference on the Adrenal Cortex (Adrenal 2016) Boston, MA, March 28–31, 2016

B. Schimmer, R. Rodgers, 2017, Molecular and Cellular Endocrinology.

Steroidogenesis and extracellular cAMP accumulation in adrenal tumor cell cultures

B. Schimmer, A. E. Zimmerman, 1976, Molecular and Cellular Endocrinology.

Regulatory domain of human protein kinase Cα dominantly inhibits protein kinase Cβ‐I regulated growth and morphology in Saccharomyces cerevisiae

B. Schimmer, A. Parissenti, Sandra A. Kim, 1996 .

Effects of mutations in cAMP‐dependent protein kinase on chloride efflux in Caco‐2 human colonic carcinoma cells

C. Bear, B. Schimmer, P. Lai, 1995, Journal of cellular physiology.

A Polymorphic Form of Steroidogenic Factor 1 Associated with ACTH Receptor Deficiency in Mouse Adrenal Cell Mutants

M. Cordova, C. Frigeri, B. Schimmer, 2003, Annals of the New York Academy of Sciences.

Mutations to forskolin resistance result in loss of adrenocorticotropin receptors and consequent reductions in levels of G protein alpha-subunits.

R. Qiu, B. Schimmer, W. K. Kwan, 1996, Molecular Endocrinology.

Defective guanyl nucleotide-binding protein beta gamma subunits in a forskolin-resistant mutant of the Y1 adrenocortical cell line.

B. Schimmer, J. Northup, J. Mitchell, 1992, Proceedings of the National Academy of Sciences of the United States of America.

A role for guanyl nucleotide-binding regulatory protein beta- and gamma-subunits in the expression of the adrenocorticotropin receptor.

R. Qiu, C. Frigeri, B. Schimmer, 1998, Molecular Endocrinology.

cAMP-binding proteins in epithelial cells cultured from human sweat glands.

J. Riordan, B. Schimmer, M. Wong, 1990, The American journal of physiology.