J. Whitton

发表

DNA immunization can stimulate florid local inflammation, and the antiviral immunity induced varies depending on injection site.

M. Yokoyama, D. Hassett, J. Zhang, 1997, Vaccine.

DNA immunization: effects of vehicle and route of administration on the induction of protective antiviral immunity.

M. Yokoyama, J. Zhang, J. Whitton, 1996, FEMS immunology and medical microbiology.

Deletions within the 5'UTR of coxsackievirus B3: consequences for virus translation and replication.

J. Whitton, I. P. Hunziker, C. Cornell, 2007, Virology.

Analysis of Translational Initiation in Coxsackievirus B3 Suggests an Alternative Explanation for the High Frequency of R+4 in the Eukaryotic Consensus Motif

J. Whitton, C. Cornell, S. Harkins, 2005, Journal of Virology.

Preferential coxsackievirus replication in proliferating/activated cells: implications for virus tropism, persistence, and pathogenesis.

J. Whitton, R. Feuer, 2008, Current topics in microbiology and immunology.

Generation and analysis of an RNA vaccine that protects against coxsackievirus B3 challenge.

J. Whitton, I. P. Hunziker, C. Cornell, 2004, Virology.

Proteins Expressed by DNA Vaccines Induce Both Local and Systemic Immune Responses a

M. Yokoyama, J. Whitton, 1996, Annals of the New York Academy of Sciences.

DNA immunization: ubiquitination of a viral protein enhances cytotoxic T-lymphocyte induction and antiviral protection but abrogates antibody induction

J. Zhang, F. Rodríguez, J. Zhang, 1997, Journal of virology.

Microorganisms and autoimmunity: making the barren field fertile?

R. Fujinami, M. V. von Herrath, J. Whitton, 2003, Nature Reviews Microbiology.

Animal Models Using Lymphocytic Choriomeningitis Virus

J. Whitton, M. Herrath, 2000, Current protocols in immunology.

DNA vaccination to treat autoimmune diabetes

M. V. von Herrath, J. Whitton, M. Herrath, 2000, Annals of medicine.

Virus-Induced Diabetes in a Transgenic Model: Role of Cross-Reacting Viruses and Quantitation of Effector T Cells Needed To Cause Disease

F. Rodríguez, M. V. von Herrath, J. Whitton, 2000, Journal of Virology.

Viruses as triggers of autoimmunity: facts and fantasies.

R. Fujinami, J. Whitton, Robert S. Fujinami, 1999, Current opinion in microbiology.

Use of a high-affinity peptide that aborts MHC-restricted cytotoxic T lymphocyte activity against multiple viruses in vitro and virus-induced immunopathologic disease in vivo.

M. V. von Herrath, J. Whitton, H. Lewicki, 1999, Virology.

DNA immunization to prevent autoimmune diabetes.

M. V. von Herrath, J. Whitton, B. Coon, 1999, The Journal of clinical investigation.

Vaccination to prevent persistent viral infection

J. Whitton, J. C. de la Torre, M. Oldstone, 1993, Journal of virology.

Fine dissection of a nine amino acid glycoprotein epitope, a major determinant recognized by lymphocytic choriomeningitis virus-specific class I-restricted H-2Db cytotoxic T lymphocytes

J. Whitton, H. Lewicki, M. Oldstone, 1988, The Journal of experimental medicine.

Analyses of the cytotoxic T lymphocyte responses to glycoprotein and nucleoprotein components of lymphocytic choriomeningitis virus.

J. Whitton, M. Oldstone, P. Southern, 1988, Virology.

Molecularly engineered vaccine which expresses an immunodominant T-cell epitope induces cytotoxic T lymphocytes that confer protection from lethal virus infection

J. Whitton, M. Oldstone, L. Klavinskis, 1989, Journal of virology.

Molecular analyses of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: an immunodominant region which induces nonreciprocal CTL cross-reactivity

J. Whitton, H. Lewicki, M. Oldstone, 1989, Journal of virology.

Replication origins and a sequence involved in coordinate induction of the immediate-early gene family are conserved in an intergenic region of herpes simplex virus.

J. Whitton, J. Clements, 1984, Nucleic acids research.

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini.

J. McLauchlan, J. Whitton, J. Clements, 1985, Nucleic acids research.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes

D. Kranz, J. Whitton, S. Harkins, 2003, Gene Therapy.

Full-length proteins attached to the HIV tat protein transduction domain are neither transduced between cells, nor exhibit enhanced immunogenicity

J. Whitton, S. Harkins, J. Leifert, 2002, Gene Therapy.

The junctions between the repetitive and the short unique sequences of the herpes simplex virus genome are determined by the polypeptide-coding regions of two spliced immediate-early mRNAs.

J. Whitton, J. Clements, Lindsay Whitton, 1984, The Journal of general virology.

Exacerbation of Viral and Autoimmune Animal Models for Multiple Sclerosis by Bacterial DNA

R. Fujinami, D. Theil, Ikuo Tsunoda, 1999, Brain pathology.

ION-BOMBARDMENT-INDUCED RADIATION DAMAGE IN SOME CERAMICS AND IONIC CRYSTALS: DETERMINED BY ELECTRON DIFFRACTION AND GAS RELEASE MEASUREMENTS

H. Matzke, J. Whitton, 1966 .

Change in stoichiometry of thin films of palladium chloride during ion beam analysis

J. Whitton, J. Williams, G. Sorensen, 1978 .

A common antiviral cytotoxic T-lymphocyte epitope for diverse major histocompatibility complex haplotypes: implications for vaccination.

J. Whitton, H. Lewicki, M. Oldstone, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Short-term fasting induces profound neuronal autophagy

W. Kiosses, M. Alirezaei, M. Wood, 2010, Autophagy.

DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection

M. Yokoyama, J. Zhang, J. Whitton, 1995, Journal of virology.

Direct Interferon-γ Signaling Dramatically Enhances CD4+ and CD8+ T Cell Memory1

J. Whitton, J. Whitmire, B. Eam, 2007, The Journal of Immunology.

Amelioration of coxsackievirus B3-mediated myocarditis by inhibition of tissue inhibitors of matrix metalloproteinase-1.

R. Frausto, J. Whitton, R. Milner, 2007, The American journal of pathology.

Coxsackievirus Targets Proliferating Neuronal Progenitor Cells in the Neonatal CNS

J. Whitton, I. P. Hunziker, S. Harkins, 2005, The Journal of Neuroscience.

Coxsackievirus replication and the cell cycle: a potential regulatory mechanism for viral persistence/latency

D. Hassett, J. Whitton, I. Mena, 2004, Medical Microbiology and Immunology.

Pancreatic acinar cell-specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo.

M. Alirezaei, M. Wood, J. Whitton, 2012, Cell host & microbe.

An autologous oral DNA vaccine protects against murine melanoma.

T. Chao, F. Rodríguez, R. Xiang, 2000, Proceedings of the National Academy of Sciences of the United States of America.

A food-responsive switch modulates TFEB and autophagy, and determines susceptibility to coxsackievirus infection and pancreatitis

M. Alirezaei, J. Whitton, Taishi Kimura, 2020, Autophagy.

Myocarditis, Microbes and Autoimmunity

J. Whitton, R. Feuer, 2004, Autoimmunity.

Immunopathology during coxsackievirus infection

J. Whitton, 2002, Springer Seminars in Immunopathology.

Inhibition of Protein Trafficking by Coxsackievirus B3: Multiple Viral Proteins Target a Single Organelle

W. Kiosses, J. Whitton, C. Cornell, 2006, Journal of Virology.

Coxsackievirus Infection Induces Autophagy-Like Vesicles and Megaphagosomes in Pancreatic Acinar Cells In Vivo

W. Kiosses, M. Alirezaei, M. Wood, 2010, Journal of Virology.

Coxsackievirus B3 Infects the Bone Marrow and Diminishes the Restorative Capacity of Erythroid and Lymphoid Progenitors

J. Whitton, N. Althof, 2012, Journal of Virology.

Neonatal DNA immunization with a plasmid encoding an internal viral protein is effective in the presence of maternal antibodies and protects against subsequent viral challenge

D. Hassett, J. Zhang, J. Whitton, 1997, Journal of virology.

Immune Responses to DNA Vaccines: Induction of CD8 T Cells

J. Whitton, J. Leifert, 2013 .

Antigen-specific regulation of T cell-mediated cytokine production.

J. Whitton, M. Slifka, 2000, Immunity.

Immunodominance in Virus-Induced CD8+ T-Cell Responses Is Dramatically Modified by DNA Immunization and Is Regulated by Gamma Interferon

F. Rodríguez, J. Whitton, M. Slifka, 2002, Journal of Virology.

CD4+ T Cells Induced by a DNA Vaccine: Immunological Consequences of Epitope-Specific Lysosomal Targeting

J. M. de Pereda, J. Whitton, S. Harkins, 2001, Journal of Virology.

A Multivalent Vaccination Strategy for the Prevention of Old World Arenavirus Infection in Humans

J. Sidney, A. Sette, M. Buchmeier, 2010, Journal of Virology.

Class I MHC can present an endogenous peptide to cytotoxic T lymphocytes

J. Whitton, M. Oldstone, J L Whitton, 1989, The Journal of experimental medicine.

DNA immunization: mechanistic studies.

J. Zhang, F. Rodríguez, D. Hassett, 1999, Vaccine.

Limiting the available T cell receptor repertoire modifies acute lymphocytic choriomeningitis virus-induced immunopathology

P. Doherty, J. Whitton, M. Oldstone, 1994, Journal of Neuroimmunology.

Molecular Anatomy of the Cytotoxic T-Lymphocyte Responses to Lymphocytic Choriomeningitis Virus

J. Whitton, M. Oldstone, L. Klavinskis, 1993 .

Novel LCMV-specific H-2k restricted CTL clones recognize internal viral gene products and cause CNS disease

J. Whitton, H. Lewicki, M. Oldstone, 1992, Journal of Neuroimmunology.

Designing arenaviral vaccines.

J. Whitton, 2002, Current topics in microbiology and immunology.

The Contraction Phase of Virus-Specific CD8+ T Cells Is Unaffected by a Pan-Caspase Inhibitor1

A. Nussbaum, J. Whitton, 2004, The Journal of Immunology.

Inhibitor T Cells Is Unaffected by a Pan-Caspase + The Contraction Phase of Virus-Specific CD 8

A. Nussbaum, J. Whitton, 2004 .

Coxsackievirus B3-induced myocarditis: perforin exacerbates disease, but plays no detectable role in virus clearance.

I. Campbell, J. Whitton, I. Mena, 1998, The American journal of pathology.

Recombinant Vaccinia Virus-Induced T-Cell Immunity: Quantitation of the Response to the Virus Vector and the Foreign Epitope

R. Ahmed, L. Harrington, J. Whitton, 2002, Journal of Virology.

Tentative T Cells: Memory Cells Are Quick to Respond, but Slow to Divide

J. Whitton, J. Whitmire, B. Eam, 2008, PLoS pathogens.

NK Markers Are Expressed on a High Percentage of Virus-Specific CD8+ and CD4+ T Cells1

J. Whitton, M. Slifka, Robb R. Pagarigan, 2000, The Journal of Immunology.

Contraction following the Resolution of T Cell + Viral Antigen Prolongs CD4 Differential T Cell Responses to Residual

M. Alirezaei, J. Whitton, J. Whitmire, 2013 .

Differential T Cell Responses to Residual Viral Antigen Prolong CD4+ T Cell Contraction following the Resolution of Infection

M. Alirezaei, J. Whitton, J. Whitmire, 2013, The Journal of Immunology.

Immune Responses following Neonatal DNA Vaccination Are Long-Lived, Abundant, and Qualitatively Similar to Those Induced by Conventional Immunization

D. Hassett, J. Whitton, M. Slifka, 2000, Journal of Virology.

Cutting Edge: Re-evaluating the In Vivo Cytokine Responses of CD8+ T Cells during Primary and Secondary Viral Infections1

J. Whitton, Fei Liu, 2005, The Journal of Immunology.

Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection

M. Alirezaei, J. Whitton, G. Sen, 2019, PLoS pathogens.

In Vivo Ablation of Type I Interferon Receptor from Cardiomyocytes Delays Coxsackieviral Clearance and Accelerates Myocardial Disease

M. Alirezaei, J. Whitton, S. Harkins, 2014, Journal of Virology.

The role of CD8+ T lymphocytes in coxsackievirus B3-induced myocarditis

J. Whitton, S. Huber, A. Stelzner, 1995, Journal of virology.

Enumeration and Functional Evaluation of Virus-Specific CD4+ and CD8+ T Cells in Lymphoid and Peripheral Sites of Coxsackievirus B3 Infection

J. Whitton, S. Harkins, C. Kemball, 2008, Journal of Virology.

"Translocatory proteins" and "protein transduction domains": a critical analysis of their biological effects and the underlying mechanisms.

J. Whitton, J. Leifert, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Coxsackievirus B3 Inhibits Antigen Presentation In Vivo, Exerting a Profound and Selective Effect on the MHC Class I Pathway

J. Whitton, S. Harkins, R. Feuer, 2009, PLoS pathogens.

Enhancing T cell activation and antiviral protection by introducing the HIV-1 protein transduction domain into a DNA vaccine.

J. Whitton, J. Charo, J. Lindencrona, 2001, Human gene therapy.

antibody induction . induction and antiviral protection but abrogates protein enhances cytotoxic T-lymphocyte DNA immunization : ubiquitination of a viral

F. Rodríguez, J. Whitton, Jie Zhang, 1997 .

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Studying RNA viruses and autophagy in VIVO

M. Alirezaei, J. Whitton, 2014 .

Coxsackievirus B3 Proteins Directionally Complement Each Other To Downregulate Surface Major Histocompatibility Complex Class I

W. Kiosses, J. Whitton, S. Harkins, 2007, Journal of Virology.

Coxsackievirus B3 Proteins Directionally Complement Each Other To Downregulate Surface Major Histocompatibility Complex Class I

W. Kiosses, J. Whitton, S. Harkins, 2007, Journal of Virology.

A Novel Population of Myeloid Cells Responding to Coxsackievirus Infection Assists in the Dissemination of Virus within the Neonatal CNS

Paul E. Gilbert, Mark A Sussman, N. Gude, 2010, The Journal of Neuroscience.

NK Markers Are Expressed on a High Percentage of Virus-Specific CD8+ and CD4+ T Cells

J. Whitton, M. Slifka, Robb R. Pagarigan, 2004, The Journal of Immunology.

Antigen Recognition by Cytotoxic T Cells

J. Whitton, M. Oldstone, 1989 .

Cutting edge: early IFN-gamma signaling directly enhances primary antiviral CD4+ T cell responses.

J. Whitton, J. Whitmire, N. Benning, 2005, Journal of immunology.

CD4 (cid:1) T Cells Induced by a DNA Vaccine: Immunological Consequences of Epitope-Speciﬁc Lysosomal Targeting†

F. Rodríguez, J. Whitton, S. Harkins, 2001 .

Plasmid DNA vaccines are effective in the absence of IFNgamma.

D. Hassett, J. Zhang, J. Whitton, 1999, Virology.

Viruses can silently prime for and trigger central nervous system autoimmune disease

R. Fujinami, D. Theil, F. Rodríguez, 2011, Journal of NeuroVirology.

Infection with a recombinant vaccinia virus encoding myelin proteolipid protein causes suppression of chronic relapsing–remitting experimental allergic encephalomyelitis

R. Fujinami, D. Theil, J. Whitton, 1999, Journal of Neuroimmunology.

Hepatocytes trap and silence coxsackieviruses, protecting against systemic disease in mice

J. Whitton, Taishi Kimura, Claudia T. Flynn, 2020, Communications biology.

Enhancement of Experimental Allergic Encephalomyelitis (EAE) by DNA Immunization with Myelin Proteolipid Protein (PLP) Plasmid DNA

R. Fujinami, Ikuo Tsunoda, J. Whitton, 1998, Journal of neuropathology and experimental neurology.

Viral Persistence and Chronic Immunopathology in the Adult Central Nervous System following Coxsackievirus Infection during the Neonatal Period

W. Kiosses, I. Campbell, J. Whitton, 2009, Journal of Virology.

Immunological and pathological consequences of coxsackievirus RNA persistence in the heart.

J. Whitton, S. Harkins, Taishi Kimura, 2017, Virology.

Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis

J. Libbey, R. Fujinami, D. Theil, 2008, Journal of Neuroimmunology.

A recombinant minigene vaccine containing a nonameric cytotoxic-T-lymphocyte epitope confers limited protection against Listeria monocytogenes infection

E. Pamer, J. Whitton, L. An, 1996, Infection and immunity.

Immediate-early mRNA-2 of herpes simplex viruses types 1 and 2 is unspliced: conserved sequences around the 5' and 3' termini correspond to transcription regulatory signals.

F. Rixon, J. Whitton, A. Easton, 1983, Nucleic acids research.

Coxsackievirus B Exits the Host Cell in Shed Microvesicles Displaying Autophagosomal Markers

A. Segall, R. Gottlieb, R. Wolkowicz, 2014, PLoS pathogens.

Intravenous administration of human embryonic stem cell‐derived neural precursor cells attenuates cuprizone‐induced central nervous system (CNS) demyelination

Glenn O. Brown, R. Bajpai, R. Frausto, 2011, Neuropathology and applied neurobiology.

Neural stem cell depletion and CNS developmental defects after enteroviral infection.

Paul E. Gilbert, Mark A Sussman, N. Gude, 2012, The American journal of pathology.

Coxsackievirus infection of the pancreas: evaluation of receptor expression, pathogenesis, and immunopathology.

J. Whitton, I. Mena, J. Gebhard, 2000, Virology.

The role of B lymphocytes in coxsackievirus B3 infection.

F. Rodríguez, J. Whitton, I. Mena, 1999, The American journal of pathology.

Silver staining of nucleic acids. Applications in virus research and in diagnostic virology.

B. O'Donnell, J. Whitton, U. Desselberger, 1983, Journal of virological methods.

Effect of Immune Priming on Borna Disease

W. Lipkin, J. Whitton, A. Lewis, 1999, Journal of Virology.

Host and virus determinants of picornavirus pathogenesis and tropism

J. Whitton, R. Feuer, Christopher T. Cornell, 2005, Nature Reviews Microbiology.

Dechanneling of MeV protons in tungsten

L. M. Howe, J. Whitton, J. Davies, 1972 .

Clinical implications of dysregulated cytokine production

J. Whitton, M. Slifka, Mark K. Slifka, 2000, Journal of molecular medicine.

Molecular Mimicry, Bystander Activation, or Viral Persistence: Infections and Autoimmune Disease

R. Fujinami, M. V. von Herrath, J. Whitton, 2006, Clinical Microbiology Reviews.

A comparison of T cell memory against the same antigen induced by virus versus intracellular bacteria.

P. Klenerman, R. Zinkernagel, J. Miller, 1999, Proceedings of the National Academy of Sciences of the United States of America.

The Regulation and Maturation of Antiviral Immune Responses

A. Nussbaum, J. Whitton, M. Slifka, 2004, Advances in Virus Research.

Ribozymes which cleave arenavirus RNAs: identification of susceptible target sites and inhibition by target site secondary structure

J. Whitton, Z. Xing, Zheng Xing, 1992, Journal of virology.

Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency

R. Frausto, J. Whitton, J. Whitmire, 2007, Journal of Neuroimmunology.

An anti-lymphocytic choriomeningitis virus ribozyme expressed in tissue culture cells diminishes viral RNA levels and leads to a reduction in infectious virus yield

J. Whitton, Z. Xing, 1993, Journal of virology.

Coxsackievirus can exploit LC3 in both autophagy-dependent and -independent manners in vivo

M. Alirezaei, M. Wood, J. Whitton, 2015, Autophagy.

Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

F. Bloom, E. Masliah, I. Campbell, 1998, Journal of immunology.

Adaptive immune responses

Abdel-Rahman B Abdel-Ghaffar, J. Whitton, 2005 .

A novel method to establish microglia‐free astrocyte cultures: Comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia

R. Frausto, J. Whitton, R. Milner, 2008, Glia.

Induction of Antiviral Antibodies by DNA Immunization Requires neither Perforin-Mediated nor CD8+-T-Cell-Mediated Lysis of Antigen-Expressing Cells

D. Hassett, J. Whitton, Jie Zhang, 1999, Journal of Virology.

Chromosomal mapping of the αMHC-MerCreMer transgene in mice reveals a large genomic deletion

J. Whitton, S. Harkins, 2016, Transgenic Research.

Coxsackievirus B3 and the neonatal CNS: the roles of stem cells, developing neurons, and apoptosis in infection, viral dissemination, and disease.

D. Hassett, J. Whitton, I. Mena, 2003, The American journal of pathology.

Astrocytic Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Promotes Oligodendrocyte Differentiation and Enhances CNS Myelination

R. Frausto, C. Moore, J. Whitton, 2011, The Journal of Neuroscience.

Rapid accumulation of measles virus leader RNA in the nucleus of infected HeLa cells and human lymphoid cells

R. Fujinami, J. Whitton, J. Ray, 1991, Journal of virology.

Peptide vaccination of mice immune to LCMV or vaccinia virus causes serious CD8 T cell-mediated, TNF-dependent immunopathology.

D. Hassett, J. Whitton, R. Feuer, 2006, The Journal of clinical investigation.

Detection of Intracellular Cytokines by Flow Cytometry

Barbara Foster, Calman Prussin, J. Whitton, 2002, Current protocols in immunology.

Persistent macrophage/microglial activation and myelin disruption after experimental autoimmune encephalomyelitis in tissue inhibitor of metalloproteinase-1-deficient mice.

R. Frausto, I. Campbell, J. Whitton, 2006, The American journal of pathology.

A cryogenic system for low-temperature and clean-environment channeling measurements

J. Whitton, J. Lori, J. Davies, 1973 .

Channeling of MeV Projectiles in Tungsten and Silicon

J. Whitton, J. Davies, J. Denhartog, 1968 .

An Electrochemical Technique for Removing Thin Uniform Layers of Gold

J. Whitton, J. A. Davies, 1964 .

Self-diffusion in gold single crystals at low temperatures

J. Whitton, G. Kidson, 1968 .

Range measurements in oriented tungsten single crystals. III. The influence of temperature on the maximum range

J. Whitton, J. Davies, L. Eriksson, 1968 .

CHANNELING IN GOLD

J. Whitton, 1967 .

Effect of temperature on the channeling of Xe 133 ions in gold

J. Whitton, D. Channing, 1964 .

Reversilibility of Fast-Charged-Particle Trajectories in Single Crystals

J. Whitton, E. Bøgh, 1967 .

Damage Profiles in Ion-Implanted Semiconductors at Low (25°K) Temperatures

D. Morgan, J. Whitton, J. Davies, 1973 .

Functional avidity maturation of CD8+ T cells without selection of higher affinity TCR

J. Whitton, M. Slifka, 2001, Nature Immunology.

LCMV-specific, class II-restricted cytotoxic T cells in beta 2-microglobulin-deficient mice.

J. Frelinger, B. Koller, J. Whitton, 1992, Science.

Identification of Protective Lassa Virus Epitopes That Are Restricted by HLA-A2

Barbara S. Stewart, Bjoern Peters, V. Pasquetto, 2006, Journal of Virology.

Molecular definition of a major cytotoxic T-lymphocyte epitope in the glycoprotein of lymphocytic choriomeningitis virus

J. Whitton, H. Lewicki, M. Oldstone, 1988, Journal of virology.

Defined Nine-Amino-Acid Immunodominant Domain of Lymphocytic Choriomeningitis Virus Glycoproteint

J. Whitton, M. Oldstone, E. Joly, 2003 .

Evaluating the immunogenicity and protective efficacy of a DNA vaccine encoding Lassa virus nucleoprotein.

M. Buchmeier, J. Whitton, J. Botten, 2005, Virology.

DNA Vaccination Can Break Immunological Tolerance to PrP in Wild-Type Mice and Attenuates Prion Disease after Intracerebral Challenge

F. Rodríguez, J. Torres, J. Whitton, 2006, Journal of Virology.

Cutting Edge: Early IFN-γ Signaling Directly Enhances Primary Antiviral CD4+ T Cell Responses1

J. Whitton, J. Whitmire, N. Benning, 2005, The Journal of Immunology.

Interferon-γ acts directly on CD8+ T cells to increase their abundance during virus infection

J. Whitton, J. Tan, J. Whitmire, 2005, The Journal of experimental medicine.

Coxsackievirus Preferentially Replicates and Induces Cytopathic Effects in Undifferentiated Neural Progenitor Cells

R. Frausto, J. Whitton, R. Feuer, 2011, Journal of Virology.

HLA-A2-Restricted Protection against Lethal Lymphocytic Choriomeningitis

J. Sidney, H. Bui, A. Sette, 2006, Journal of Virology.

Two Overlapping Subdominant Epitopes Identified by DNA Immunization Induce Protective CD8+ T-Cell Populations with Differing Cytolytic Activities

J. Whitton, M. Slifka, S. Harkins, 2001, Journal of Virology.

Fatal neonatal myocarditis caused by a recombinant human enterovirus-B variant.

J. Whitton, P. Krogstad, R. Hammon, 2008, The Pediatric infectious disease journal.

Type B coxsackieviruses and their interactions with the innate and adaptive immune systems.

M. Alirezaei, J. Whitton, C. Kemball, 2010, Future microbiology.

Hepatocytes trap and silence coxsackieviruses, protecting against systemic disease in mice

J. Whitton, Taishi Kimura, Claudia T. Flynn, 2020, Communications Biology.

CD4-deficient mice have reduced levels of memory cytotoxic T lymphocytes after immunization and show diminished resistance to subsequent virus challenge

M. V. von Herrath, M. Yokoyama, J. Whitton, 1996, Journal of virology.

A "string-of-beads" vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge

J. Whitton, M. Oldstone, T. McKee, 1993, Journal of virology.

An overview of antigen presentation and its central role in the immune response.

J. Whitton, J L Whitton, 1998, Current topics in microbiology and immunology.

A multivalent minigene vaccine, containing B-cell, cytotoxic T-lymphocyte, and Th epitopes from several microbes, induces appropriate responses in vivo and confers protection against more than one pathogen

J. Whitton, L. An, L L An, 1997, Journal of virology.

Mice deficient in stem cell antigen‐1 (Sca1, Ly‐6A/E) develop normal primary and memory CD4+ and CD8+ T‐cell responses to virus infection

J. Whitton, J. Whitmire, B. Eam, 2009, European journal of immunology.

Cell Cycle Status Affects Coxsackievirus Replication, Persistence, and Reactivation In Vitro

J. Whitton, M. Slifka, I. Mena, 2002, Journal of Virology.

Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis

G. Robertson, R. Frausto, W. Kiosses, 2009, Autophagy.

Rapid on/off cycling of cytokine production by virus-specific CD8+ T cells

Fernando Rodriguez, F. Rodríguez, J. Whitton, 1999, Nature.

Antigen-Specific Naive CD8+ T Cells Produce a Single Pulse of IFN-γ In Vivo within Hours of Infection, but without Antiviral Effect

J. Whitton, Martin P. Hosking, Claudia T. Flynn, 2014, The Journal of Immunology.

Using Recombinant Coxsackievirus B3 To Evaluate the Induction and Protective Efficacy of CD8+ T Cells during Picornavirus Infection

J. Whitton, M. Slifka, I. Mena, 2001, Journal of Virology.

Virus encoding an encephalitogenic peptide protects mice from experimental allergic encephalomyelitis

R. Fujinami, J. Whitton, L. Barnett, 1996, Journal of Neuroimmunology.

Induction of Protective Immunity Using Minigenes a

J. Whitton, 1994, Annals of the New York Academy of Sciences.

DNA Immunization with Minigenes: Low Frequency of Memory Cytotoxic T Lymphocytes and Inefficient Antiviral Protection Are Rectified by Ubiquitination

Fernando Rodriguez, Iain L. Campbell, Jie Zhang, 1998, Journal of Virology.

Wild-type coxsackievirus infection dramatically alters the abundance, heterogeneity, and immunostimulatory capacity of conventional dendritic cells in vivo.

J. Whitton, J. Botten, Martin P. Hosking, 2012, Virology.

Type I IFN Signaling Is Dispensable during Secondary Viral Infection

J. Whitton, Martin P. Hosking, Claudia T. Flynn, 2016, PLoS pathogens.

Identification of Db- and Kb-restricted subdominant cytotoxic T-cell responses in lymphocytic choriomeningitis virus-infected mice.

C Oseroff, J Alexander, R W Chesnut, 1998, Virology.

Vaccination and protection from a lethal viral infection: identification, incorporation, and use of a cytotoxic T lymphocyte glycoprotein epitope.

J. Whitton, M. Oldstone, E. Joly, 1990, Virology.

The Rapidity with Which Virus-Specific CD8+ T Cells Initiate IFN-γ Synthesis Increases Markedly over the Course of Infection and Correlates with Immunodominance1

J. Whitton, M. Slifka, Fei Liu, 2004, The Journal of Immunology.

CD8+ Memory T Cells Appear Exhausted within Hours of Acute Virus Infection

J. Whitton, J. Botten, Martin P. Hosking, 2013, The Journal of Immunology.

CTL escape viral variants. II. Biologic activity in vivo.

M. V. von Herrath, J. Whitton, H. Lewicki, 1995, Virology.

Immunoproteasome-Deficient Mice Mount Largely Normal CD8+ T Cell Responses to Lymphocytic Choriomeningitis Virus Infection and DNA Vaccination1

A. Nussbaum, J. Whitton, N. Benning, 2005, The Journal of Immunology.

Infection and DNA Vaccination Lymphocytic Choriomeningitis Virus T Cell Responses to + Largely Normal CD 8 Immunoproteasome-Deficient Mice Mount

A. Nussbaum, J. Whitton, N. Benning, 2005 .

DNA Immunization in an Arenavirus Model

M. Yokoyama, J. Zhang, J. Whitton, 1996 .

Erratum: NK markers are expressed on a high percentage of virus-specific CD8+ and CD4+ T cells (Journal of Immunology (March 15, 2000) 164 (2009-2015))

J. Whitton, M. Slifka, Robb R. Pagarigan, 2000 .

Use of a nonviral vector to express a chimeric tRNA-ribozyme against lymphocytic choriomeningitis virus: cytoplasmic accumulation of a catalytically competent transcript but minimal antiviral effect.

J. Whitton, J. Gebhard, C. M. Perry, 1997, Antisense & nucleic acid drug development.

Antiviral activity of RNA molecules containing self-releasing ribozymes targeted to lymphocytic choriomeningitis virus.

J. Whitton, Z. Xing, S. Mahadeviah, 1995, Antisense research and development.

Antisense-mediated resistance to measles virus infection in HeLa cells.

R. Fujinami, J. Whitton, A. Bell, 1997, The Journal of infectious diseases.

Neonates Mount Robust and Protective Adult-Like CD8+-T-Cell Responses to DNA Vaccines

D. Hassett, J. Whitton, Jie Zhang, 2002, Journal of Virology.

Quantitative and qualitative analyses of the immune responses induced by a multivalent minigene DNA vaccine.

F. Rodríguez, J. Zhang, J. Whitton, 2000, Vaccine.

Autophagy, inflammation and neurodegenerative disease

M. Alirezaei, J. Whitton, C. Kemball, 2011, The European journal of neuroscience.

A modular system for the assay of transcription regulatory signals: the sequence TAATGARAT is required for herpes simplex virus immediate early gene activation.

J. McLauchlan, J. Whitton, J. Clements, 1985, Nucleic acids research.

Protection of Mice against Lethal Coxsackievirus B3 Infection by Using DNA Immunization

J. Whitton, R. Zell, A. Stelzner, 1998, Journal of Virology.

Direct Ex Vivo Kinetic and Phenotypic Analyses of CD8+ T-Cell Responses Induced by DNA Immunization

J Zhang, D. Hassett, J. Whitton, 2000, Journal of Virology.

Vaccination protects beta 2 microglobulin deficient mice from immune mediated mortality but not from persisting viral infection.

David A Hildeman, J. Whitton, M. Salvato, 1996, Vaccine.

Increasing the CD4+ T Cell Precursor Frequency Leads to Competition for IFN-γ Thereby Degrading Memory Cell Quantity and Quality1

J. Whitton, J. Lindsay Whitton, J. Whitmire, 2008, The Journal of Immunology.

Activated and Memory CD8+ T Cells Can Be Distinguished by Their Cytokine Profiles and Phenotypic Markers1

J. Whitton, M. Slifka, Mark K. Slifka, 2000, The Journal of Immunology.

Enhancement of autoimmune disease using recombinant vaccinia virus encoding myelin proteolipid protein

R. Fujinami, J. Whitton, Y. Wada, 1993, Journal of Neuroimmunology.

REVIEW Autophagy, inflammation and neurodegenerative disease

M. Alirezaei, J. Whitton, C. Kemball, 2011 .

TCR independent suppression of CD8(+) T cell cytokine production mediated by IFNγ in vivo.

J. Whitton, Martin P. Hosking, Claudia T. Flynn, 2016, Virology.

Antiviral Effect In Vivo within Hours γ a Single Pulse of IFN-T Cells Produce + Antigen-Specific Naive CD 8

J. Whitton, Martin P. Hosking, Claudia T. Flynn, 2014 .

The Dependence of Electronic Stopping Cross Section of 42K on Different Target Materials

J. Whitton, 1974 .

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

A rapid, inexpensive method for eluting DNA from agarose or acrylamide gel slices without using toxic or chaotropic materials.

J. Whitton, H. Schwarz, 1992, BioTechniques.

Direct interferon-gamma signaling dramatically enhances CD4+ and CD8+ T cell memory.

J. Whitton, J. Whitmire, B. Eam, 2007, Journal of immunology.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Principles of cytotoxic T lymphocyte induction and recognition.

J. Zhang, J. Whitton, 1995, Current topics in microbiology and immunology.

Precursor Frequency, Nonlinear Proliferation, and Functional Maturation of Virus-Specific CD4+ T Cells1

J. Whitton, J. Whitmire, N. Benning, 2006, The Journal of Immunology.

Virus-Specific CD 4 Proliferation , and Functional Maturation of Precursor Frequency , Nonlinear

J. Whitton, J. Whitmire, N. Benning, 2006 .

Interactions between enteroviruses and autophagy in vivo

M. Alirezaei, J. Whitton, Claudia T. Flynn, 2012, Autophagy.

RANGES OF HEAVY IONS

L. M. Howe, J. Whitton, G. Ball, 1965 .

Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-alpha/beta.

A. Stalder, I. Campbell, J. Zhang, 1994, Journal of immunology.

Chromosomal mapping of the αMHC-MerCreMer transgene in mice reveals a large genomic deletion

J. Whitton, S. Harkins, 2016, Transgenic Research.

Adaptive immune responses

R. Fujinami, J. Whitton, C. Kemball, 2005 .

A novel method to establish microglia‐free astrocyte cultures: Comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia

R. Frausto, J. Whitton, R. Milner, 2008, Glia.

Enhancing DNA immunization.

F. Rodríguez, J. Whitton, J L Whitton, 2000, Virology.

Infection Contraction following the Resolution of T Cell + Viral Antigen Prolong Cd4 Differential T Cell Responses to Residual

J. Whitton, J. Whitmire, Su, 2022 .

Coxsackievirus B3 Infects the Bone Marrow and Diminishes the Restorative Capacity of Erythroid and Lymphoid Progenitors

J. Whitton, N. Althof, 2012, Journal of Virology.

Interferon-γ acts directly on CD8+ T cells to increase their abundance during virus infection

J. Whitton, J. Whitmire, Joyce T. Tan, 2005, The Journal of experimental medicine.

Polymorphism of cytotoxic T-lymphocyte clones that recognize a defined nine-amino-acid immunodominant domain of lymphocytic choriomeningitis virus glycoprotein

J. Whitton, M. Oldstone, E. Joly, 1989, Journal of virology.