J. Callahan

发表

Maturation and degradation of β‐galactosidase in the post‐Golgi compartment are regulated by cathepsin B and a non‐cysteine protease

Y. Okamura-Oho, S. Zhang, J. Callahan, 1997, FEBS letters.

Identification of the gene encoding the enzyme deficient in mucopolysaccharidosis IIIC (Sanfilippo disease type C).

J. Callahan, D. Mahuran, R. Bagshaw, 2006, American journal of human genetics.

A Proteomic Analysis of Lysosomal Integral Membrane Proteins Reveals the Diverse Composition of the Organelle*S

Richard D. Bagshaw, John W. Callahan, J. Callahan, 2005, Molecular & Cellular Proteomics.

Membrane‐associated estrogen receptor and caveolin‐1 are present in central nervous system myelin and oligodendrocyte plasma membranes

J. Boggs, J. Callahan, D. Arvanitis, 2004, Journal of neuroscience research.

Functional post-translational proteomics approach to study the role of N-glycans in the development of Caenorhabditis elegans.

J. Rosa, Y. She, V. Reinhold, 2002, Biochemical Society symposium.

G M1 -gangliosidosis (Type II): studies on a fibroblast cell strain.

J. Callahan, L. Pinsky, L. Wolfe, 1970, Biochemical medicine.

The role of the endosomal/lysosomal system in amyloid-beta production and the pathophysiology of Alzheimer's disease: reexamining the spatial paradox from a lysosomal perspective.

S. Pasternak, J. Callahan, D. Mahuran, 2003, Journal of Alzheimer's disease : JAD.

Aggregation of plasma Z type α1‐antitrypsin suggests basic defect for the deficiency

D. Cox, J. Callahan, G. Billingsley, 1986 .

Effect of saposins on acid sphingomyelinase.

B. Martin, Y. Kishimoto, J. Callahan, 1993, The Biochemical journal.

Purification and proteomic analysis of lysosomal integral membrane proteins.

J. Callahan, D. Mahuran, R. Bagshaw, 2008, Methods in molecular biology.

Nicastrin is a resident lysosomal membrane protein.

S. Pasternak, J. Callahan, D. Mahuran, 2003, Biochemical and biophysical research communications.

The 67-kDa Enzymatically Inactive Alternatively Spliced Variant of β-Galactosidase Is Identical to the Elastin/Laminin-binding Protein*

J. Callahan, A. Hinek, S. Privitera, 1998, The Journal of Biological Chemistry.

Molecular basis of GM1 gangliosidosis and Morquio disease, type B. Structure-function studies of lysosomal beta-galactosidase and the non-lysosomal beta-galactosidase-like protein.

J. Callahan, 1999, Biochimica et biophysica acta.

Characterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1 gangliosidosis.

S. Zhang, J. Callahan, J. Clarke, 2000, The Biochemical journal.

Novel mutations (Asn 484 Lys, Thr 500 Ala, Gly 438 Glu) in Morquio B disease.

J. Callahan, J. Clarke, R. Bagshaw, 2002, Biochimica et biophysica acta.

Expression and characterization of 14 GLB1 mutant alleles found in GM1-gangliosidosis and Morquio B patients Published, JLR Papers in Press, July 30, 2007.

J. Callahan, D. Grinberg, A. Chabás, 2007, Journal of Lipid Research.

Isoenzymes of sphingomyelinase and the genetic defect in Niemann-Pick disease, type C.

J. Callahan, M. Khalil, J. Gerrie, 1974, Biochemical and biophysical research communications.

Purification of GM 1-ganglioside and ceramide lactoside β-galactosidase from rabbit brain

J. Callahan, J. Gerrie, 1975 .

The integral membrane of lysosomes: its proteins and their roles in disease.

J. Callahan, D. Mahuran, R. Bagshaw, 2009, Journal of proteomics.

Desalting of in-gel-digested protein sample with mini-C18 columns for matrix-assisted laser desorption ionization time of flight peptide mass fingerprinting.

J. Callahan, D. Mahuran, R. Bagshaw, 2000, Analytical biochemistry.

Lysosomal membrane proteomics and biogenesis of lysosomes

J. Callahan, D. Mahuran, R. Bagshaw, 2005, Molecular Neurobiology.

Evaluation of N-nonyl-deoxygalactonojirimycin as a pharmacological chaperone for human GM1 gangliosidosis leads to identification of a feline model suitable for testing enzyme enhancement therapy.

Douglas R Martin, J. Callahan, E. Crushell, 2012, Molecular genetics and metabolism.

Late-onset Tay-Sachs disease presenting as catatonic schizophrenia: diagnostic and treatment issues.

G. MacQueen, J. Callahan, M. Mazurek, 1995, The Journal of clinical psychiatry.

Lysosphingolipids and mitochondrial function. II. Deleterious effects of sphingosylphosphorylcholine.

J. Callahan, P. Strasberg, Paula M. Strasberg, 1988, Biochemistry and cell biology = Biochimie et biologie cellulaire.

The active site of lysosomal sphingomyelinase: Evidence for the involvement of hydrophobic and ionic groups

J. Callahan, C. S. Jones, D. Davidson, 1983, Journal of neuroscience research.

The 67-kD elastin/laminin-binding protein is related to an enzymatically inactive, alternatively spliced form of beta-galactosidase.

Y. Okamura-Oho, J. Callahan, F. Keeley, 1993, The Journal of clinical investigation.

Phosphodiesterases in human tissues. II. Decreased hydrolysis of synthetic substrate by tissues from patients with the Niemann-Pick syndrome.

J. Callahan, M. Philippart, E. Lassila, 1974, Biochemical Medicine.

Lysosomes and lysosomal storage diseases

J. Callahan, J. Lowden, 1981 .

Decreased elastin deposition and high proliferation of fibroblasts from Costello syndrome are related to functional deficiency in the 67-kD elastin-binding protein.

R. Weksberg, K. Gripp, J. Callahan, 2000, American journal of human genetics.

The biochemistry and clinical features of galactosialidosis.

Y. Okamura-Oho, S. Zhang, J. Callahan, 1994, Biochimica et biophysica acta.

Genotype‐phenotype pitfalls in Gaucher disease

L. Becker, J. Callahan, J. Clarke, 1994, Journal of clinical laboratory analysis.

Isolation and characterization of keratan sulfates from the liver of a patient with GM1-gangliosidosis type I.

J. Callahan, L. Wolfe, 1970, Biochimica et biophysica acta.

GM1‐gangliosidosis without chondrodystrophy or visceromegaly

F. Andermann, J. Callahan, C. Scriver, 1970, Neurology.

Early-infantile galactosialidosis: prenatal presentation and postnatal follow-up.

D. Chitayat, M. Patel, J. Callahan, 1999, American journal of medical genetics.

Cholesterol-Enriched Membrane Microdomains Are Required for Inducing Host Cell Cytoskeleton Rearrangements in Response to Attaching-Effacing Escherichia coli

J. Callahan, P. Sherman, Jason D Riff, 2005, Infection and Immunity.

Characteristics of the fl-galactosidase-carboxypeptidase complex in Gm 1-gangliosidosis and f-galactosialidosis fibroblasts

J. Callahan, R. Shankaran, R. M. D'Agrosa, 2005 .

The amino‐terminal sequences in the pro‐α and ‐β polypeptides of human lysosomal β‐hexosaminidase A and B are retained in the mature isozymes

J. Callahan, D. Mahuran, R. Gravel, 1989 .

Lysosomal membranes from beige mice contain higher than normal levels of endoplasmic reticulum proteins.

J. Callahan, D. Mahuran, R. Bagshaw, 2007, Journal of proteome research.

Niemann-Pick Disease Type C

J. Opitz, J. Callahan, E. Gilbert, 1981, European Journal of Pediatrics.

Ocular involvement in Niemann-Pick disease type B.

S. Packman, J. Callahan, D. Wenger, 1986 .

Sphingomyelinases in Human Tissues. II. Absence of a Specific Enzyme from Liver and Brain of Niemann-Pick Disease, Type C

J. Callahan, M. Philippart, M. Khalil, 1975, Pediatric Research.

Niemann-Pick disease (Crocker's group A). Late onset and pigmentary degeneration resembling Hallervorden-Spatz syndrome.

J. Martín, J. Callahan, M. Philippart, 1972, Archives of neurology.

Gene transfer therapy of gaucher disease

J. Callahan, P. Thorner, J. Clarke, 1996 .

Cholesterol esterification and Niemann–Pick disease: An approach to identifying the defect in fibroblasts

J. Callahan, L. Bowler, I. Das, 1990, Journal of neuroscience research.

Caprine beta-D-mannosidosis: characterization of a model lysosomal storage disorder.

J. Callahan, J. Clarke, P. Little, 1990, Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.

Studies on the activation of the enzymatic hydrolysis of sphingomyelin liposomes.

A. Poulos, J. Callahan, E. Ranieri, 1984, Biochimica et biophysica acta.

Lysosomal Sphingomyelinase: Patients with Niemann-Pick Disease Have Normal Amounts of Sphingomyelinase Polypeptide

J. Callahan, E. Jobb, 1988 .

Development of a clinical assay for detection of GAA mutations and characterization of the GAA mutation spectrum in a Canadian cohort of individuals with glycogen storage disease, type II.

F. Bamforth, P. Chakraborty, J. Callahan, 2007, Molecular genetics and metabolism.

A comparative study of cytoplasmic granules imaged by the real-time microscope, Nile Red and Filipin in fibroblasts from patients with lipid storage diseases

N. Pham, J. Callahan, R. Bagshaw, 2005, Journal of Inherited Metabolic Disease.

An α-subunit loop structure is required for GM2 activator protein binding by β-hexosaminidase A

J. Callahan, D. Mahuran, M. Tropak, 2004 .

Biosynthesis of sphingomyelinase in normal and Niemann-Pick fibroblasts.

J. Callahan, E. Jobb, 1989, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Identification of proteins in the ceroid-like autofluorescent aggregates from liver lysosomes of Beige, a mouse model for human Chediak-Higashi syndrome.

J. Callahan, D. Mahuran, Huiwen Zhang, 2010, Molecular genetics and metabolism.

Properties of partially purified goat kidney β-D-mannosidase

J. Callahan, A. Novak, J. Clarke, 1990 .

Lectin-mediated uptake of lysosomal hydrolases by genetically deficient human fibroblasts.

R. Juliano, J. Callahan, M. Moore, 1979, Experimental cell research.

The Arf-family protein, Arl8b, is involved in the spatial distribution of lysosomes.

J. Callahan, D. Mahuran, R. Bagshaw, 2006, Biochemical and biophysical research communications.

Monoclonal antibodies against human placental sphingomyelinase

D. Davidson, J. Callahan, S. Freeman, 1983, Bioscience reports.

Juvenile GM1 gangliosidosis. Occurrence with absence of two beta-galactosidase components.

J. Callahan, M. Norman, J. Prichard, 1974, Archives of neurology.

In vitro activation of neuraminidase in the beta-galactosidase-neuraminidase-protective protein complex by cathepsin C.

J. Callahan, R. M. D'Agrosa, 1988, Biochemical and biophysical research communications.

Nerve biopsy findings in Niemann-Pick type II (NPC)

C. Bolton, J. Callahan, A. Hahn, 2004, Acta Neuropathologica.

Sphingomyelinases and the genetic defects in Niemann-Pick disease.

J. Callahan, M. Khalil, 1976, Advances in experimental medicine and biology.

The effect of lipid micelles on mitochondrial malate dehydrogenase.

J. Callahan, G. Kosicki, 1967, Canadian journal of biochemistry.

Macrophage phagocytosis of polyethylene particulate in vitro.

J. Santerre, J. Callahan, A. Hinek, 1998, Journal of biomedical materials research.

Solid-phase assay for the detection of low-abundance enzymes, and antibodies to enzymes in immune reactions, using acid sphingomyelinase as a model.

D. Davidson, J. Callahan, S. Freeman, 1984, Analytical biochemistry.

Alpha-N-acetylgalactosaminidase: isolation, properties and distribution of the human enzyme.

J. Callahan, M. Philippart, E. Lassila, 1973, Biochemical medicine.

Fabry's disease as an -galactosidosis: evidence for an -configuration in trihexosyl ceramide.

J. Callahan, M. Philippart, I. Bensaude, 1971, Biochemical and biophysical research communications.

Homozygous presence of the crossover (fusion gene) mutation identified in a type II Gaucher disease fetus: is this analogous to the Gaucher knock-out mouse model?

J. Callahan, J. Clarke, P. Strasberg, 1994, Biochemical medicine and metabolic biology.

First trimester prenatal diagnosis of Tay-Sachs disease using the sulfated synthetic substrate for hexosaminidase A.

J. Callahan, J. Clarke, C. Shuman, 1990, Clinical biochemistry.

Concanavalin A promotes the uptake of lysosomal hydrolases by human fibroblasts.

R. Juliano, J. Callahan, M. Moore, 1978, Biochimica et biophysica acta.

GM1-gangliosidosis Types 1 and 2: Enzymatic Differences in Cultured Fibroblasts

J. Callahan, L. Pinsky, E. Powell, 1970, Nature.

Hexosaminidases: multiple component enzymes.

J. Callahan, J. Lowden, F. Howard, 1976, Advances in experimental medicine and biology.

Complex kinetics of bis(4-methylumbelliferyl)phosphate and hexadecanoyl(nitrophenyl)phosphorylcholine hydrolysis by purified sphingomyelinase in the presence of Triton X-100.

D. Davidson, J. Callahan, C. S. Jones, 1982, Biochimica et biophysica acta.

Purification of sphingomyelinase to apparent homogeneity by using hydrophobic chromatography.

J. Callahan, C. S. Jones, P. Shankaran, 1981, The Biochemical journal.

Induction of hemopoietic chimerism in the caprine fetus by intraperitoneal injection of fetal liver cells

J. Callahan, D. Armstrong, J. Clarke, 1989, Experientia.

Presenilin-1, Nicastrin, Amyloid Precursor Protein, and γ-Secretase Activity Are Co-localized in the Lysosomal Membrane*

C. Ackerley, B. Pak, S. Pasternak, 2003, Journal of Biological Chemistry.

Studies on the Activation of Sphingomyelinase Activity in Niemann-Pick Type A, B, and C Fibroblasts: Enzymological Differentiation of Types A and B

A. Poulos, J. Callahan, E. Ranieri, 1984, Pediatric Research.

Sphingomyelinases in Human Tissues. III. Expression of Niemann-Pick Disease in Cultured Skin Fibroblasts

J. Callahan, M. Khalil, 1975, Pediatric Research.

An alpha-subunit loop structure is required for GM2 activator protein binding by beta-hexosaminidase A.

J. Callahan, D. Mahuran, M. Tropak, 2004, Biochemical and biophysical research communications.

Identification of Glu-268 as the Catalytic Nucleophile of Human Lysosomal β-Galactosidase Precursor by Mass Spectrometry*

S. Withers, J. McCarter, J. Callahan, 1997, The Journal of Biological Chemistry.

Impaired elastic-fiber assembly by fibroblasts from patients with either Morquio B disease or infantile GM1-gangliosidosis is linked to deficiency in the 67-kD spliced variant of beta-galactosidase.

S. Zhang, J. Callahan, Sunqu Zhang, 2000, American journal of human genetics.

Recycling of the 67-kDa elastin binding protein in arterial myocytes is imperative for secretion of tropoelastin.

J. Callahan, F. Keeley, A. Hinek, 1995, Experimental cell research.

Phosphodiesterases in human tissues. I. Identification and separation of enzymes active on bis(p-nitrophenyl)phosphate.

J. Callahan, M. Philippart, E. Lassila, 1974, Biochemical medicine.

Studies on the hydrophobic properties of sphingomyelinase.

J. Callahan, J. Gerrie, C. S. Jones, 1981, The Biochemical journal.

Identification of the hydrophobic glycoproteins of Caenorhabditis elegans.

Y. She, J. Callahan, H. Schachter, 2005, Glycobiology.

A single site in human beta-hexosaminidase A binds both 6-sulfate-groups on hexosamines and the sialic acid moiety of GM2 ganglioside.

J. Callahan, D. Mahuran, S. Bukovac, 2003, Biochimica et biophysica acta.

Sulfatide and Na+-K+-ATPase: A Salinity-sensitive Relationship in the Gill Basolateral Membrane of Rainbow Trout

D. Lingwood, J. Callahan, J. Ballantyne, 2004, The Journal of Membrane Biology.

Pulmonary infiltration in Niemann-Pick disease type C

B. Shuckett, J. Callahan, J. Clarke, 1996, Journal of Inherited Metabolic Disease.

Human placental beta-galactosidase. Characterization of the dimer and complex forms of the enzyme.

J. Callahan, M. Hubbes, R. M. D'Agrosa, 1992, The Biochemical journal.

Deficiency of phospholipase C acting on phosphatidylglycerol in Niernann‐Pick disease

J. Wherrett, A. Poulos, J. Callahan, 1983, Neurology.

Regulation of mRNAs for Three Enzymes in the Glial Cell Model C6 Cell Line

S. Kumar, J. Callahan, J. Vellis, 1984, Journal of neurochemistry.

The subunit of human sphingomyelinase is not the same size in all tissues: Studies with a polyclonal rabbit serum

J. Callahan, E. Jobb, 1987, Journal of Inherited Metabolic Disease.

Heterogeneity of Human Sphingomyelinase: Relatedness of the Major Polypeptides

D. Davidson, J. Callahan, P. Strasberg, 1986 .

Studies on the structure of sphingomyelinase. Amino acid composition and heterogeneity on isoelectric focusing.

D. Davidson, A. Poulos, J. Callahan, 1983, The Biochemical journal.

Arginine Esterase and Lysosomal Hydrolases in Liver from Cystic Fibrosis Subjects

J. Callahan, A. Leung, 1977, Pediatric Research.

Selective damage to cochlear efferents by the choline neurotoxin ethylcholine mustard aziridinium ion (AF64A) in the chinchilla

R. J. Mount, J. Callahan, David Smith, 1989, Hearing Research.

Sphingomyelinases in human tissues. IV. Purification of sphingomyelinase from human placenta and effect of Triton X-100.

J. Callahan, M. Khalil, J. Gerrie, 1978, Canadian journal of biochemistry.

Classification of disorders of GM2 ganglioside hydrolysis using 3H-GM2 as substrate.

J. Callahan, A. Novak, J. Lowden, 1994, Biochimica et biophysica acta.

Kinetic mechanism and characterization of human beta-galactosidase precursor secreted by permanently transfected Chinese hamster ovary cells.

S. Withers, Y. Okamura-Oho, J. McCarter, 1994, The Biochemical journal.

Early proteolytic cleavage with loss of a C-terminal fragment underlies altered processing of the beta-galactosidase precursor in galactosialidosis.

Y. Okamura-Oho, S. Zhang, J. Callahan, 1996, The Biochemical journal.

Molecular consequences of the pathogenic mutation in feline GM1 gangliosidosis.

H. J. Baker, J. Callahan, Bruce F. Smith, 2008, Molecular genetics and metabolism.

Type 2 GM1 gangliosidosis with long survival and neuronal ceroid lipofuscinosis

L. Becker, J. Callahan, J. Groves, 1981, Neurology.

Diagnosis of Krabbe disease by use of a natural substrate.

J. Callahan, M. Skomorowski, 2006, Methods in molecular biology.

Infantile sialidosis: a phenocopy of type 1 GM1 gangliosidosis distinguished by genetic complementation and urinary oligosaccharides.

J. Callahan, R. Gravel, L. Wolfe, 1979, American journal of human genetics.

IDENTIFICATION OF THE HYDROPHOBIC GLYCOPROTEINS OF

J. Callahan, R. Bagshaw, Xiaolian Fan, 2005 .

A method for proteomic identification of membrane-bound proteins containing Asn-linked oligosaccharides.

Y. She, J. Callahan, H. Schachter, 2004, Analytical biochemistry.

Enzymatic hydrolysis of sphingomyelin liposomes by normal tissues and tissues from patients with Niemann-Pick disease.

A. Poulos, J. Callahan, C. S. Jones, 1983, Biochimica et biophysica acta.

Psychosine and Sphingosylphosphorylcholine Bind to Mitochondrial Membranes and Disrupt their Function

J. Callahan, P. Strasberg, 1988 .

Macrophage phagocytosis of polyethylene particulate in vitro.

J. Santerre, J. Callahan, A. Hinek, 1998, Journal of biomedical materials research.