G. Cain

发表

Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter.

D. Harats, A. Ziober, Y. Kurihara, 1995, The Journal of clinical investigation.

Targeting gene expression to the vascular wall in transgenic mice using the murine preproendothelin-1 promoter.

D. Harats, A. Ziober, Y. Kurihara, 1995 .

Pharmacokinetic drivers of toxicity for basic molecules: strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor.

Kevin A Ford, D. Sutherlin, M. Merchant, 2013, Toxicology and applied pharmacology.

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X 3-deficient mice

Geoffrey Burnstock, D. Cockayne, G. Burnstock, 2000, Nature.

Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function.

D. Cockayne, A. Ford, T. Sun, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Lung-restricted inhibition of Janus kinase 1 is effective in rodent models of asthma

Adam R. Johnson, N. C. Ray, G. Cain, 2018, Science Translational Medicine.

An Automated Image Analysis Method to Quantify Veterinary Bone Marrow Cellularity on H&E Sections

G. Cain, Cleopatra Kozlowski, J. Brumm, 2018, Toxicologic pathology.

Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer

P. Hegde, J. Martens, J. Vogt, 2018, PloS one.

Balancing Efficacy and Safety of an Anti-DLL4 Antibody through Pharmacokinetic Modulation

P. Hass, N. Lewin-Koh, J. Ridgway, 2015, Clinical Cancer Research.

Bioerosion and biocompatibility of poly(d,l-lactic-co-glycolic acid) implants in brain

G. Cain, J. H. Kou, L. M. Sanders, 1997 .

Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3A Receptor Subunit

H. Lester, D. Cockayne, A. Ford, 2004, The Journal of Neuroscience.

Proof of Concept for an Automated Image Analysis Method to Quantify Rat Bone Marrow Hematopoietic Lineages on H&E Sections

G. Cain, Cleopatra Kozlowski, Aaron M Fullerton, 2018, Toxicologic pathology.

MEK and ERK Kinase Inhibitors Increase Circulating Ceruloplasmin and Cause Green Serum in Rats

G. Cain, D. Dambach, N. La, 2017, Toxicologic pathology.

Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window.

I. Aliagas, K. Hoeflich, Weiru Wang, 2016, Journal of medicinal chemistry.

Combination Drug Scheduling Defines a “Window of Opportunity” for Chemopotentiation of Gemcitabine by an Orally Bioavailable, Selective ChK1 Inhibitor, GNE-900

Ivana Yen, S. Malek, T. O'Brien, 2013, Molecular Cancer Therapeutics.

Small Molecule Therapeutics Combination Drug Scheduling De fi nes a " Window of Opportunity " for Chemopotentiation of Gemcitabine by an Orally Bioavailable , Selective ChK 1 Inhibitor , GNE-900

Ivana Yen, S. Malek, T. O'Brien, 2013 .

Urinary bladder hypore ̄ exia and reduced pain-related behaviour in P 2 X 3-de ® cient mice

D. Cockayne, G. Burnstock, A. Ford, 2022 .

Effects of Anti-VEGF on Pharmacokinetics, Biodistribution, and Tumor Penetration of Trastuzumab in a Preclinical Breast Cancer Model

M. Sliwkowski, F. Theil, L. Khawli, 2012, Molecular Cancer Therapeutics.

Toxicity profile of small-molecule IAP antagonist GDC-0152 is linked to TNF-α pharmacology.

W. Fairbrother, K. Amemiya, H. Wong, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Generation and characterization of a unique reagent that recognizes a panel of recombinant human monoclonal antibody therapeutics in the presence of endogenous human IgG

R. Kelley, C. Eigenbrot, V. Quarmby, 2013, mAbs.

Tpl2 kinase regulates inflammation but not tumorigenesis in mice.

A. Zarrin, G. Cain, K. Wu, 2021, Toxicology and applied pharmacology.

Preclinical Safety Assessment of a Highly Selective and Potent Dual Small-Molecule Inhibitor of CBP/P300 in Rats and Dogs

F. A. Romero, G. Cain, E. Choo, 2020, Toxicologic pathology.

Phosphorous dysregulation induced by MEK small molecule inhibitors in the rat involves blockade of FGF-23 signaling in the kidney.

Dolores Diaz, Cleopatra Kozlowski, Donna M Dambach, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Mechanism for platelet reduction in anti-neuropilin-1 (MNRP1685A)-treated phase I patients.

P. LoRusso, A. Patnaik, R. Brachmann, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Smarca2 genetic ablation is phenotypically benign in a safety assessment of tamoxifen-inducible conditional knockout rats.

T. Januario, R. Yauch, G. Cain, 2023, Toxicology and applied pharmacology.

Assessment of placental transfer and the effect on embryo-fetal development of a humanized monoclonal antibody targeting lymphotoxin-alpha in non-human primates.

Hong Wang, G. Cain, J. Grogan, 2016, Reproductive toxicology.

Phosphorous dysregulation induced by MEK small molecule inhibitors in the rat involves blockade of FGF-23 signaling in the kidney.

G. Cain, Cleopatra Kozlowski, D. Dambach, 2012, Toxicological Sciences.

Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function.

D. Cockayne, A. Ford, T. Sun, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

MEK and ERK Kinase Inhibitors Increase Circulating Ceruloplasmin and Cause Green Serum in Rats

G. Cain, D. Dambach, N. La, 2017, Toxicologic pathology.

Preclinical stereoselective disposition and toxicokinetics of two novel MET inhibitors

D. Sutherlin, Xingrong Liu, B. Liederer, 2012, Xenobiotica; the fate of foreign compounds in biological systems.