A. Irie

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Selective Coupling of Prostaglandin E Receptor EP3D to Gi and Gs through Interaction of α-Carboxylic Acid of Agonist and Arginine Residue of Seventh Transmembrane Domain (*)

Y. Sugimoto, A. Ichikawa, M. Negishi, 1995, The Journal of Biological Chemistry.

The C-terminus of the prostaglandin-E-receptor EP3 subtype is essential for activation of GTP-binding protein.

Y. Sugimoto, A. Ichikawa, M. Negishi, 1994, European journal of biochemistry.

Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

S. Narumiya, A. Kakizuka, S. Ito, 1993, Nature.

Heparan sulfate is required for bone morphogenetic protein-7 signaling.

A. Irie, K. Kimata, H. Habuchi, 2003, Biochemical and biophysical research communications.

Chondroitin sulfate disrupts axon pathfinding in the optic tract and alters growth cone dynamics.

C. Holt, C. Chien, A. Irie, 2002, Journal of neurobiology.

Senile cataract-related accumulation of Lewis(x) glycolipid in human lens.

A. Irie, M. Hoshi, M. Ogiso, 1992, The Journal of biological chemistry.

Characterization of neutral glycosphingolipids in rat lens.

A. Irie, M. Hoshi, M. Ogiso, 1995, Experimental eye research.

The Molecular Basis for the Absence ofN-Glycolylneuraminic Acid in Humans*

Y. Kozutsumi, A. Suzuki, A. Irie, 1998, The Journal of Biological Chemistry.

CMP-N-Acetylneuraminic acid hydroxylase is exclusively inactive in humans.

A. Suzuki, A. Irie, 1998, Biochemical and biophysical research communications.

Induction of experimental bone metastasis in mice by transfection of integrin α4β1 into tumor cells

Y. Takada, N. Matsuura, A. Irie, 1996 .

Critical Residues of Integrin αIIb Subunit for Binding of αIIbβ3 (Glycoprotein IIb-IIIa) to Fibrinogen and Ligand-mimetic Antibodies (PAC-1, OP-G2, and LJ-CP3)*

Y. Takada, A. Irie, T. Kamata, 1996, The Journal of Biological Chemistry.

Phosphatidylethanolamine dynamics are required for osteoclast fusion

Y. Miki, Kei Yamamoto, M. Murakami, 2017, Scientific Reports.

Third isoform of the prostaglandin-E-receptor EP3 subtype with different C-terminal tail coupling to both stimulation and inhibition of adenylate cyclase.

Y. Sugimoto, A. Ichikawa, M. Negishi, 1993, European journal of biochemistry.

Opposite Coupling of Prostaglandin E Receptor EPsc with G, and Go

Y. Sugimoto, M. Negishi, A. Irie, 1993 .

Cloning and expression of a cDNA for mouse prostaglandin F receptor.

A. Kakizuka, Y. Sugimoto, A. Ichikawa, 1994, The Journal of biological chemistry.

Induction of experimental bone metastasis in mice by transfection of integrin alpha 4 beta 1 into tumor cells.

Y. Takada, N. Matsuura, A. Irie, 1996, The American journal of pathology.

Cloning and expression of a cDNA for mouse prostaglandin E receptor EP2 subtype.

Y. Sugimoto, A. Ichikawa, M. Negishi, 1993, The Journal of biological chemistry.

Multiple loop structures critical for ligand binding of the integrin α4 subunit in the upper face of the β-propeller mode 1

Y. Takada, A. Irie, T. Kamata, 1997 .

Specific binding of glycyrrhetinic acid to the rat liver membrane.

A. Ichikawa, M. Negishi, A. Irie, 1991, Biochimica et biophysica acta.

Signal transductions of three isoforms of mouse prostaglandin E receptor EP3 subtype.

Y. Sugimoto, A. Ichikawa, M. Negishi, 1995, Advances in prostaglandin, thromboxane, and leukotriene research.

Critical amino acid residues for ligand binding are clustered in a predicted beta‐turn of the third N‐terminal repeat in the integrin alpha 4 and alpha 5 subunits.

Y. Takada, A. Irie, T. Kamata, 1995, The EMBO journal.

In Vitro Osteoclast Differentiation of Bone Marrow Cells on Hydroxyapatite/Collagen Self-Organized Bone-Like Nanocomposite Disk

A. Irie, M. Kikuchi, 2008 .

Aeromonas sobria Released from Production of C5a by ASP, a Serine Protease

K. Okamoto, A. Irie, T. Imamura, 2008 .

Cloning and expression of cDNA for a mouse EP1 subtype of prostaglandin E receptor.

S. Ito, Y. Sugimoto, A. Ichikawa, 1993, The Journal of biological chemistry.

[The molecular basis for the absence of N-glycolylneuraminic acid in humans].

Y. Kozutsumi, A. Suzuki, A. Irie, 1998, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

Two isoforms of prostaglandin E receptor EP3 subtype. Different COOH-terminal domains determine sensitivity to agonist-induced desensitization.

Y. Sugimoto, A. Ichikawa, M. Negishi, 1993, The Journal of biological chemistry.

Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model.

T. Springer, Y. Takada, A. Irie, 2001, The Journal of biological chemistry.

Opposite coupling of prostaglandin E receptor EP3C with Gs and G(o). Stimulation of Gs and inhibition of G(o).

T. Katada, Y. Sugimoto, A. Ichikawa, 1993, The Journal of biological chemistry.

Gangliosides from the eggs of the sea urchin, Anthocidaris crassispina.

F. Inagaki, A. Irie, H. Kubo, 1990, Journal of biochemistry.

Synthesis of Hydroxyapatite/Collagen Bone-Like Nanocomposite and Its Biological Reactions

K. Edamura, Shigeo M. Tanaka, Y. Koyama, 2011 .

Glucosylceramide having a novel tri-unsaturated long-chain base from the spermatozoa of the starfish, Asterias amurensis.

A. Irie, H. Kubo, M. Hoshi, 1990, Journal of biochemistry.

An artificial cationic oligosaccharide combined with phosphorothioate linkages strongly improves siRNA stability

F. Shibasaki, Kazuki Sato, A. Irie, 2020, Scientific Reports.

Structural basis of integrin-mediated signal transduction.

Y. Takada, A. Irie, T. Kamata, 1997, Matrix biology : journal of the International Society for Matrix Biology.

Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory anti-alpha5 and anti-beta1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the alpha5 subunit.

S. Aota, M. Humphries, A. Mould, 1997, The Journal of biological chemistry.

α3β1 Adhesion to Laminin-5 and Invasin: Critical and Differential Role of Integrin Residues Clustered at the Boundary between α3 N-Terminal Repeats 2 and 3†

Y. Takada, A. Irie, X. Zhang, 1999 .

Ganglioside GT1b in rat brain binds to p58, a brain-specific sodium-dependent inorganic phosphate cotransporter: expression cloning with a specific monoclonal antibody to ganglioside GT1b-binding protein.

H. Kubo, A. Irie, T. Tai, 2000, Journal of biochemistry.

Amino Acid Residues in the αIIb Subunit That Are Critical for Ligand Binding to Integrin αIIbβ3 Are Clustered in the β-Propeller Model*

T. Springer, Y. Takada, A. Irie, 2001, The Journal of Biological Chemistry.

Cloning and expression of a cDNA for the human prostacyclin receptor

S. Narumiya, Y. Sugimoto, A. Ichikawa, 1994, FEBS letters.

Characterization of neutral glycosphingolipids in human cataractous lens.

Y. Koide, A. Irie, M. Hoshi, 1993, The Journal of biological chemistry.

The Role of α and β Chains in Ligand Recognition by β7 Integrins*

K. Tan, Jia-huai Wang, Y. Takada, 2000, The Journal of Biological Chemistry.

Tissue specific control of glyco-chains

Y. Kikkawa, H. Yonekawa, R. Kannagi, 2001 .

Heparin enhances osteoclastic bone resorption by inhibiting osteoprotegerin activity.

M. Takami, A. Irie, Y. Sanai, 2007, Bone.

Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies

S. Aota, M. Humphries, A. Mould, 1997, The Journal of Biological Chemistry.

Multiple loop structures critical for ligand binding of the integrin alpha4 subunit in the upper face of the beta-propeller mode 1.

Y. Takada, A. Irie, T. Kamata, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Melibiosylceramide as the sole ceramide dihexoside from the eggs of the sea urchin, Anthocidaris crassispina.

F. Inagaki, A. Irie, H. Kubo, 1988, Journal of biochemistry.

Specific heparan sulfate structures involved in retinal axon targeting.

Atsushi Irie, C. Holt, J. Turnbull, 2002, Development.

Mouse prostaglandin E receptor EP3 subtype mediates calcium signals via Gi in cDNA-transfected Chinese hamster ovary cells.

Y. Sugimoto, A. Ichikawa, M. Negishi, 1994, Biochemical and biophysical research communications.

Induction of a 31,000-dalton stress protein by prostaglandins D2 and J2 in porcine aortic endothelial cells.

A. Ichikawa, M. Negishi, A. Irie, 1991, Biochemical pharmacology.

Complementary DNA cloning and characterization of RANDAM‐2, a type I membrane molecule specifically expressed on glutamatergic neuronal cells in the mouse cerebrum

H. Shitara, K. Iwatsuki, A. Irie, 2003, Journal of neuroscience research.

The role of alpha and beta chains in ligand recognition by beta 7 integrins.

Y. Takada, A. Irie, M. Brenner, 2000, The Journal of biological chemistry.

A novel ceramide trihexoside from the eggs of the sea urchin, Hemicentrotus pulcherrimus.

A. Irie, G. Jiang, H. Kubo, 1992, Journal of biochemistry.

Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3).

Y. Takada, A. Irie, T. Kamata, 1996, The Journal of biological chemistry.

Glycyrrhetinic acid bound to 11 beta-hydroxysteroid dehydrogenase in rat liver microsomes.

A. Ichikawa, M. Negishi, A. Irie, 1992, Biochimica et Biophysica Acta.