I. Sagami

发表

Aberrant CYP1A1 Induction: Discrepancy of CYP1A1 mRNA and Aryl Hydrocarbon Hydroxylase Activity in Mutant Cells of Mouse Hepatoma Line, Hepa‐1

S. Ikawa, H. Kikuchi, M. Usuda, 1994, Japanese journal of cancer research : Gann.

Activation of heme-regulated eukaryotic initiation factor 2alpha kinase by nitric oxide is induced by the formation of a five-coordinate NO-heme complex: optical absorption, electron spin resonance, and resonance raman spectral studies.

J. Igarashi, Toru Shimizu, S. Yamauchi, 2004, The Journal of biological chemistry.

Analysis of the kinetics of CO binding to neuronal nitric oxide synthase by flash photolysis: dual effects of substrates, inhibitors, and tetrahydrobiopterin.

J. Igarashi, Toru Shimizu, O. Ito, 2004, Journal of inorganic biochemistry.

Rapid Calmodulin-dependent Interdomain Electron Transfer in Neuronal Nitric-oxide Synthase Measured by Pulse Radiolysis*

Toru Shimizu, S. Tagawa, S. Daff, 2001, The Journal of Biological Chemistry.

The 42-Amino Acid Insert in the FMN Domain of Neuronal Nitric-oxide Synthase Exerts Control over Ca2+/Calmodulin-dependent Electron Transfer*

S. Daff, I. Sagami, T. Shimizu, 1999, The Journal of Biological Chemistry.

Characterization of a direct oxygen sensor heme protein from Escherichia coli. Effects of the heme redox states and mutations at the heme-binding site on catalysis and structure.

Shingo Suzuki, Miki Watanabe, Toru Shimizu, 2002, The Journal of biological chemistry.

Binding of Oxygen and Carbon Monoxide to a Heme-regulated Phosphodiesterase from Escherichia coli

J. Igarashi, Toru Shimizu, O. Ito, 2004, Journal of Biological Chemistry.

Identification of two factors required for transcription of the ovalbumin gene

H. Wang, B. O’Malley, M. Tsai, 1986, Molecular and cellular biology.

Effects of NAD(P)H and its derivatives on the DNA-binding activity of NPAS2, a mammalian circadian transcription factor.

I. Sagami, S. Ishijima, Katsuhiro Yoshii, 2013, Biochemical and biophysical research communications.

Changes in pH and NADPH regulate the DNA binding activity of neuronal PAS domain protein 2, a mammalian circadian transcription factor.

I. Sagami, S. Ishijima, Katsuhiro Yoshii, 2015, Biochemistry.

Azo reduction of methyl red by neuronal nitric oxide synthase: the important role of FMN in catalysis.

S. Daff, I. Sagami, T. Shimizu, 2000, Biochemical and biophysical research communications.

Liver microsomal drug metabolism in ethanol-treated hamsters.

M. Watanabe, H. Fujii, I. Sagami, 1985, Biochemical pharmacology.

CO binding studies of nitric oxide synthase: effects of the substrate, inhibitors and tetrahydrobiopterin

Toru Shimizu, S. Daff, O. Ito, 1998, FEBS letters.

Human cytochrome P450IIE1 gene: DraI polymorphism and susceptibility to cancer.

R. Kanamaru, C. Ishioka, H. Kikuchi, 1992, The Tohoku journal of experimental medicine.

Imaging of heme/hemeproteins in nucleus of the living cells expressing heme‐binding nuclear receptors

I. Sagami, S. Taketani, Ken-Ichi Fujita, 2013, FEBS letters.

Importance of valine 567 in substrate recognition and oxidation by neuronal nitric oxide synthase.

J. Boucher, D. Mansuy, M. Sari, 2004, Journal of inorganic biochemistry.

Circadian clock disruption by selective removal of endogenous carbon monoxide

I. Sagami, H. Kitagishi, S. Negi, 2018, Scientific Reports.

Human Geranylgeranyl Diphosphate Synthase

I. Sagami, H. Sagami, K. Ogura, 1999, The Journal of Biological Chemistry.

Activation of Heme-regulated Eukaryotic Initiation Factor 2α Kinase by Nitric Oxide Is Induced by the Formation of a Five-coordinate NO-Heme Complex

J. Igarashi, Toru Shimizu, S. Yamauchi, 2004, Journal of Biological Chemistry.

Distal site and surface mutations of cytochrome P450 1A2 markedly enhance dehalogenation of chlorinated hydrocarbons.

I. Sagami, T. Shimizu, K. Yanagita, 1997, Archives of biochemistry and biophysics.

Electron transfer in nitric-oxide synthase

S. Daff, Yuko Sato, Toru Shimizu, 2002 .

Critical role of the neuronal nitric-oxide synthase heme proximal side residue, Arg418, in catalysis and electron transfer.

I. Sagami, T. Shimizu, Y. Sato, 2001, Journal of inorganic biochemistry.

Important role of tetrahydrobiopterin in no complex formation and interdomain electron transfer in neuronal nitric-oxide synthase.

S. Daff, I. Sagami, T. Shimizu, 2001, Biochemical and biophysical research communications.

Unusual role of Tyr588 of neuronal nitric oxide synthase in controlling substrate specificity and electron transfer.

I. Sagami, T. Shimizu, T. Matsui, 2001, Biochemical and biophysical research communications.

Association between Restriction Fragment Length Polymorphism of the Human Cytochrome P450IIE1 Gene and Susceptibility to Lung Cancer

R. Kanamaru, H. Kikuchi, I. Sagami, 1991, Japanese journal of cancer research : Gann.

Potentiometric analysis of the flavin cofactors of neuronal nitric oxide synthase.

A. Munro, M. Noble, L. Robledo, 1999, Biochemistry.

Chiral recognition at the heme active site of nitric oxide synthase is markedly enhanced by L-arginine and 5,6,7,8-tetrahydrobiopterin.

K. Nakano, S. Daff, I. Sagami, 1998, Biochemical and biophysical research communications.

The N=N Bond Cleavage of Angeli’s Salt Is Markedly Enhanced by Cytochrome P-450 1A2: Effects of Distal Amino Acid Mutations on the Formation of Nitric Oxide Complexes

Toru Shimizu, I. Sagami, Hideaki Sato, 1998 .

Identification of Caveolin-1-interacting Sites in Neuronal Nitric-oxide Synthase

Yuko Sato, Toru Shimizu, I. Sagami, 2004, Journal of Biological Chemistry.

Cyanide binding study of neuronal nitric oxide synthase: effects of inhibitors and mutations at the substrate binding site.

Toru Shimizu, I. Sagami, J. Yadav, 2003, Journal of inorganic biochemistry.

CO binding to the isolated oxygenase domain of neuronal nitric oxide synthase: effects of inhibitors and mutations at the substrate-binding site.

Toru Shimizu, I. Sagami, Simona Bengea, 2003, Journal of inorganic biochemistry.

Interactions between the Isolated Oxygenase and Reductase Domains of Neuronal Nitric-oxide Synthase

S. Daff, Toru Shimizu, I. Sagami, 2002, The Journal of Biological Chemistry.

Intra-subunit and Inter-subunit Electron Transfer in Neuronal Nitric-oxide Synthase

Toru Shimizu, S. Daff, I. Sagami, 2001, The Journal of Biological Chemistry.

[36] Aspulvinone dimethylallyltransferase

I. Sagami, N. Ojima, K. Ogura, 1985 .

Aromatic Residues and Neighboring Arg414 in the (6R)-5,6,7,8-Tetrahydro-l-Biopterin Binding Site of Full-length Neuronal Nitric-oxide Synthase Are Crucial in Catalysis and Heme Reduction with NADPH*

Toru Shimizu, S. Daff, I. Sagami, 2000, The Journal of Biological Chemistry.

MspI polymorphism of the human CYP2E gene.

H. Kikuchi, I. Sagami, M. Motomiya, 1991, Nucleic acids research.

ROLE OF CYTOCHROME P-450 IN CHEMICAL TOXICITY AND CARCINOGENESIS

H. Fujii, H. Kikuchi, I. Sagami, 1989 .

Functional reconstitution and characterization of the Arabidopsis Mg(2+) transporter AtMRS2-10 in proteoliposomes.

I. Sagami, S. Ishijima, Zenpei Shigemi, 2012, Biochimica et biophysica acta.

Binding of gymnemic acid II to mammalian glycerol-3-phosphate dehydrogenase

I. Sagami, S. Ishijima, Shuhei Nomura, 2022, Journal of Biological Macromolecules.

Comparison of wild type neuronal nitric oxide synthase and its Tyr588Phe mutant towards various L-arginine analogues.

J. Boucher, D. Mansuy, Toru Shimizu, 2010, Journal of inorganic biochemistry.

Complementary DNA sequence of 3-methylcholanthrene-inducible P-450 from the rat lung.

M. Watanabe, H. Fujii, H. Kikuchi, 1990, The Tohoku journal of experimental medicine.

The homologous Arabidopsis MRS2/MGT/CorA-type Mg2+ channels, AtMRS2-10 and AtMRS2-1 exhibit different aluminum transport activity.

I. Sagami, S. Ishijima, Ayumi Hotta, 2018, Biochimica et biophysica acta. Biomembranes.

Assessment of cancer susceptibility in humans by use of genetic polymorphisms in carcinogen metabolism.

M. Osada, S. Ikawa, H. Kikuchi, 1995, Pharmacogenetics.

Functional analysis of whether the glycine residue of the GMN motif of the Arabidopsis MRS2/MGT/CorA-type Mg2+ channel protein AtMRS2-11 is critical for Mg2+ transport activity.

I. Sagami, S. Ishijima, Rikako Shiomi, 2020, Archives of biochemistry and biophysics.

SOUL in mouse eyes is a new hexameric heme-binding protein with characteristic optical absorption, resonance Raman spectral, and heme-binding properties.

T. Uchida, J. Igarashi, Toru Shimizu, 2004, Biochemistry.

CO binding study of mouse heme-regulated eIF-2alpha kinase: kinetics and resonance Raman spectra.

J. Igarashi, Toru Shimizu, I. Sagami, 2003, Biochimica et biophysica acta.

Unusual cyanide bindings to a heme-regulated phosphodiesterase from Escherichia coli: effect of Met95 mutations.

Miki Watanabe, Toru Shimizu, I. Sagami, 2002, Biochemical and biophysical research communications.

Spectroscopic and DNA‐binding characterization of the isolated heme‐bound basic helix–loop–helix‐PAS‐A domain of neuronal PAS protein 2 (NPAS2), a transcription activator protein associated with circadian rhythms

Yuko Sato, T. Uchida, J. Igarashi, 2006, The FEBS journal.

Exhaustive syntheses of naphthofluoresceins and their functions.

I. Sagami, N. Tokitoh, T. Sasamori, 2012, The Journal of organic chemistry.

Thermodynamic analysis of interactions between cofactor and neuronal nitric oxide synthase.

M. Oda, I. Sagami, S. Ishijima, 2011, Biochemistry.

Benzo[a]pyrene metabolism by purified cytochrome P-450 from 3-methylcholanthrene-treated rats.

M. Watanabe, H. Fujii, I. Sagami, 1987, Xenobiotica; the fate of foreign compounds in biological systems.

Stationary and Time-resolved Resonance Raman Spectra of His77 and Met95 Mutants of the Isolated Heme Domain of a Direct Oxygen Sensor from Escherichia coli *

Y. Mizutani, Toru Shimizu, I. Sagami, 2002, The Journal of Biological Chemistry.

Purification and characterization of chicken ovalbumin upstream promoter transcription factor from HeLa cells.

B. O’Malley, M. Tsai, S. Tsai, 1987, The Journal of biological chemistry.

Restriction fragment length polymorphism of the human CYP2E1 (cytochrome P450IIE1) gene and susceptibility to lung cancer: possible relevance to low smoking exposure.

R. Kanamaru, S. Ikawa, H. Kikuchi, 1994, Pharmacogenetics.

Tissue difference in expression of cytochrome P-450 between liver and lung of Syrian golden hamsters treated with 3-methylcholanthrene.

M. Watanabe, H. Fujii, H. Kikuchi, 1991, Advances in experimental medicine and biology.

Magnesium uptake of Arabidopsis transporters, AtMRS2-10 and AtMRS2-11, expressed in Escherichia coli mutants: Complementation and growth inhibition by aluminum.

I. Sagami, S. Ishijima, M. Shibata, 2015, Biochimica et biophysica acta.

The novel heme-dependent inducible protein, SRRD regulates heme biosynthesis and circadian rhythms.

Y. Ohkawa, Tetsuya Sato, Mana Umeda, 2017, Archives of biochemistry and biophysics.

Critical role of Val567 in substrate recognition by neuronal nitric oxide synthase for NO formation activity

J. Boucher, D. Mansuy, M. Sari, 2003 .

Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II)

B. O’Malley, M. Tsai, S. Tsai, 1987, Cell.

Characterization of heme-regulated eIF2alpha kinase: roles of the N-terminal domain in the oligomeric state, heme binding, catalysis, and inhibition.

J. Igarashi, Toru Shimizu, S. Yamauchi, 2006, Biochemistry.

The Crucial Roles of Asp-314 and Thr-315 in the Catalytic Activation of Molecular Oxygen by Neuronal Nitric-oxide Synthase

Toru Shimizu, I. Sagami, 1998, The Journal of Biological Chemistry.

A Redox-controlled Molecular Switch Revealed by the Crystal Structure of a Bacterial Heme PAS Sensor*

B. Mikami, Miki Watanabe, Toru Shimizu, 2004, Journal of Biological Chemistry.

Circadian clock disruption by selective removal of endogenous carbon monoxide

I. Sagami, H. Kitagishi, S. Negi, 2018, Scientific Reports.

Spectroscopic characterization of the isolated heme‐bound PAS‐B domain of neuronal PAS domain protein 2 associated with circadian rhythms

T. Uchida, J. Igarashi, Toru Shimizu, 2005, The FEBS journal.

Characteristics of Purified Cytochrome P-450s in Microsomes of Rat Lung and Morris Hepatoma 5123D

H. Fujii, I. Sagami, Minro Watanabe, 1985 .

Multiplicity of cytochrome P-450 in Morris hepatoma.

M. Watanabe, I. Sagami, T. Ohmachi, 1986, Advances in experimental medicine and biology.

Characterization of hepatic and pulmonary cytochromes P-450 in 3-methylcholanthrene-treated hamsters

H. Fujii, I. Sagami, Minro Watanabe, 2004, Archives of Toxicology.

DOSEc, a Heme-Regulated Phosphodiesterase, Plays an Important Role in the Regulation of the Cyclic AMP Level in Escherichia coli

Toru Shimizu, I. Sagami, H. Kurokawa, 2005, Journal of bacteriology.

Relationships between Heme Incorporation, Tetramer Formation, and Catalysis of a Heme-regulated Phosphodiesterase from Escherichia coli

Toru Shimizu, I. Sagami, Yukie Sasakura, 2003, Journal of Biological Chemistry.

Structure and Function Relationships of a Redox-Sensor Protein, Heme-Regulated Phosphodiesterase

J. Igarashi, Toru Shimizu, S. Hirata, 2005 .

Critical roles of Asp40 at the haem proximal side of haem-regulated phosphodiesterase from Escherichia coli in redox potential, auto-oxidation and catalytic control.

Miki Watanabe, Toru Shimizu, I. Sagami, 2004, European journal of biochemistry.

Fluorescence Spectra of Trp53Phe and Trp110Ile Mutants of a Heme-regulated Phosphodiesterase from Escherichia coli

Toru Shimizu, S. Hirata, I. Sagami, 2004 .

Effects of the bHLH domain on axial coordination of heme in the PAS-A domain of neuronal PAS domain protein 2 (NPAS2): conversion from His119/Cys170 coordination to His119/His171 coordination.

T. Uchida, K. Ishimori, Toru Shimizu, 2012, Journal of inorganic biochemistry.

Effects of mutations in the heme domain on the transcriptional activity and DNA-binding activity of NPAS2.

T. Ueha, I. Sagami, Mashiho Ishida, 2008, Biochemical and biophysical research communications.

CO-dependent Activity-controlling Mechanism of Heme-containing CO-sensor Protein, Neuronal PAS Domain Protein 2*

T. Uchida, Toru Shimizu, I. Sagami, 2005, Journal of Biological Chemistry.

Identification of cellular protein that can interact specifically with the basic helix-loop-helix domain of the aromatic hydrocarbon receptor.

S. Ikawa, H. Kikuchi, I. Sagami, 1995, Biochemical and biophysical research communications.

Identification of a 120-kDa protein associated with aromatic hydrocarbon receptor nuclear translocator.

S. Ikawa, H. Kikuchi, I. Sagami, 1995, Biochemical and biophysical research communications.

Interaction of Angeli's salt with cytochrome P450 1A2 distal mutants: an optical absorption spectral study.

I. Sagami, T. Shimizu, H. Sato, 1997, Biochimica et biophysica acta.

Roles of the heme proximal side residues tryptophan409 and tryptophan421 of neuronal nitric oxide synthase in the electron transfer reaction.

S. Daff, I. Sagami, T. Shimizu, 2000, Journal of inorganic biochemistry.

Crucial Role of Lys423 in the Electron Transfer of Neuronal Nitric-oxide Synthase*

S. Daff, Toru Shimizu, I. Sagami, 1999, The Journal of Biological Chemistry.

Autoxidation rates of neuronal nitric oxide synthase: effects of the substrates, inhibitors, and modulators.

S. Daff, I. Sagami, T. Shimizu, 1998, Biochemical and biophysical research communications.

Roles of the Heme Proximal Amino Acids in the Active Site Structure and the NO Formation Activity in Neuronal Nitric Oxide Synthase

Toru Shimizu, S. Daff, I. Sagami, 2001 .

Crucial role of Lys(423) in the electron transfer of neuronal nitric-oxide synthase.

S. Daff, I. Sagami, T. Shimanuki, 1999, The Journal of biological chemistry.

Characterization of Met95 mutants of a heme-regulated phosphodiesterase from Escherichia coli. Optical absorption, magnetic circular dichroism, circular dichroism, and redox potentials.

Toru Shimizu, S. Hirata, I. Sagami, 2003, European journal of biochemistry.

Control of electron transfer in neuronal NO synthase.

A. Munro, M. Noble, S. Daff, 2001, Biochemical Society transactions.

Catalytically functional flavocytochrome chimeras of P450 BM3 and nitric oxide synthase.

A. Munro, M. Noble, S. Chapman, 2002, Journal of inorganic biochemistry.

Microsomal monooxygenase system in Morris hepatoma: purification and characterization of cytochromes P-450 from Morris hepatoma 5123D of 3-methylcholanthrene-treated rats.

M. Watanabe, H. Fujii, I. Sagami, 1985, Archives of biochemistry and biophysics.

Different inducibility of cytochrome P-4501A1 mRNA of human and mouse by omeprazole in culture cells.

S. Ikawa, H. Kikuchi, I. Sagami, 1995, Archives of biochemistry and biophysics.

Human Cytochrome Polymorphism and P 450 I I E 1 Gene : Dra I Susceptibility to Cancer

R. Kanamaru, C. Ishioka, I. Sagami, 2006 .

Susceptibility to Cancer

R. Kanamaru, C. Ishioka, I. Sagami, 1992 .

Two common RFLPs of the human CYP2E gene.

T. Kamataki, H. Kikuchi, I. Sagami, 1991, Nucleic acids research.

Purification and characterization of cytochromes P-450 from liver microsomes of 3-methylcholanthrene-treated crab-eating monkeys.

M. Watanabe, H. Fujii, I. Sagami, 1989, Journal of Biochemistry (Tokyo).

Thermodynamic Characterization of the Ca2+-Dependent Interaction Between SOUL and ALG-2

I. Sagami, S. Ishijima, S. Taketani, 2018, International journal of molecular sciences.

Marked enhancement in the reductive dehalogenation of hexachloroethane by a Thr319Ala mutation of cytochrome P450 1A2.

S. Daff, I. Sagami, T. Shimizu, 1998, Biochemical and biophysical research communications.

Purification and characterization of pulmonary cytochrome P-450 from 3-methylcholanthrene-treated rats.

M. Watanabe, I. Sagami, 1983, Journal of biochemistry.