A. Clark

发表

Molecular cloning of the canine angiotensin II receptor

L. Burns, K. Clark, J. Bradley, 1994, FEBS letters.

Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro

M. Korbonits, A. Grossman, A. Clark, 2003, Journal of Endocrinological Investigation.

Are activating mutations of the adrenocorticotropin receptor involved in adrenal cortical neoplasia?

S. Asa, R. Clayton, A. Clark, 1995, Life sciences.

Cloning and expression of a novel angiotensin II receptor subtype.

K. Catt, H. Shapira, A. Clark, 1992, The Journal of biological chemistry.

Identification of an orphan receptor gene as a type 1 calcitonin gene-related peptide receptor.

A. Clark, S. Kapas, 1995, Biochemical and biophysical research communications.

Cloning and Expression of cDNA Encoding a Rat Adrenomedullin Receptor (*)

K. Catt, A. Clark, S. Kapas, 1995, The Journal of Biological Chemistry.

Adrenomedullin acts via stimulation of cyclic AMP and not via calcium signalling in vascular cells in culture.

A. Clark, S. Kapas, S. Barker, 1996, Journal of human hypertension.

Expression of adrenomedullin (ADM) and its binding sites in the rat uterus: increased number of binding sites and ADM messenger ribonucleic acid in 20-day pregnant rats compared with nonpregnant rats.

D. Smith, M. Ghatei, A. Clark, 1997, Endocrinology.

The expression of the ACTH receptor.

A. Clark, L. Elias, 2000, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

The ACTH receptor.

A. Clark, F. Cammas, 1996, Bailliere's clinical endocrinology and metabolism.

Elevated epidermal growth factor receptor gene copy number and expression in a squamous carcinoma cell line.

I. Pastan, S. Ishii, G. Merlino, 1985, The Journal of clinical investigation.

ACTH and α-MSH inhibit leptin expression and secretion in 3T3-L1 adipocytes: model for a central–peripheral melanocortin-leptin pathway

S. Chew, A. Isidori, A. Grossman, 2003, Molecular and Cellular Endocrinology.

An alternatively spliced human insulin-like growth factor-I transcript with hepatic tissue expression that diverts away from the mitogenic IBE1 peptide.

S. Chew, R. Ross, A. Clark, 1995, Endocrinology.

POMC gene-derived peptides activate melanocortin type 3 receptor on murine macrophages, suppress cytokine release, and inhibit neutrophil migration in acute experimental inflammation.

M. Perretti, R. Flower, L. Gibbs, 1999, Journal of immunology.

Bromocriptine inhibits pro-opiomelanocortin mRNA and ACTH precursor secretion in small cell lung cancer cell lines.

M. F. Stewart, W. Farrell, A. Clark, 1992, The Journal of clinical investigation.

Stimulation of early gene expression by angiotensin II in bovine adrenal glomerulosa cells: roles of calcium and protein kinase C.

K. Catt, T. Balla, A. Clark, 1992, Molecular endocrinology.

Desensitization of the Y1 Cell Adrenocorticotropin Receptor

L. Hunyady, A. Baig, A. Clark, 2001, The Journal of Biological Chemistry.

The synthesis of ACTH and related peptides by tumours.

M. F. Stewart, A. Clark, A. White, 1990, Bailliere's clinical endocrinology and metabolism.

The influence of plasma on basal and ACTH-stimulated in vitro adrenocortical steroidogenesis.

A. Clark, P. Jenkins, L. Perry, 1999, The Journal of endocrinology.

AGONIST ACTIVATED ADRENOCORTICOTROPIN RECEPTOR INTERNALIZES VIA A CLATHRIN-MEDIATED G PROTEIN RECEPTOR KINASE DEPENDENT MECHANISM

L. Hunyady, A. Baig, A. Clark, 2002, Endocrine research.

Adrenocorticotropin insensitivity syndromes.

A. Clark, A. Weber, A. Clark, 1998, Endocrine reviews.

Absence of mutations in the MEN2A region of the ret proto‐oncogene in non‐MEN 2A phaeochromocytomas

S. Chew, R. Ross, A. Clark, 1995, Clinical endocrinology.

Expression of IGFBP-1 in normal and cirrhotic human livers.

J. Holly, R. Ross, A. Clark, 1994, The Journal of endocrinology.

Synthesis of epidermal growth factor (EGF) receptor in vitro using SP6 RNA polymerase-transcribed template mRNA.

B. Roe, I. Pastan, S. Ishii, 1986, Biochimica et biophysica acta.

Pro-opiomelanocortin mRNA size heterogeneity in ACTH-dependent Cushing's syndrome.

A. Clark, G. Besser, L. Rees, 1989, Journal of molecular endocrinology.

The mas oncogene enhances angiotensin-induced [Ca2+]i responses in cells with pre-existing angiotensin II receptors.

K. Catt, A. Clark, C. Ambroz, 1991, Biochimica et biophysica acta.

Effects of the selective protein kinase C inhibitor Ro 31‐7549 on human angiotensin II receptor desensitisation and intracellular calcium release

R. Fluck, A. Clark, S. Kapas, 1995, FEBS letters.

The aberrant expression of the gastric inhibitory polypeptide (GIP) receptor in adrenal hyperplasia: does chronic adrenocorticotropin exposure stimulate up-regulation of GIP receptors in Cushing's disease?

A. Grossman, J. Arola, S. Aylwin, 2005, The Journal of clinical endocrinology and metabolism.

Mutations of the ACTH receptor gene are only one cause of familial glucocorticoid deficiency.

A. Clark, A. Weber, Adrian J.L.Clark, 1994, Human molecular genetics.

Familial glucocorticoid deficiency associated with point mutation in the adrenocorticotropin receptor

A. Clark, A. Grossman, L. Mcloughlin, 1993, The Lancet.

Desensitisation of calcitonin gene-related peptide responsiveness but not adrenomedullin responsiveness in vascular smooth muscle cells.

W. Drake, A. Clark, T. Bartlett, 2000, The Journal of endocrinology.

Expression of pro-opiomelanocortin gene and quantification of adrenocorticotropic hormone-like immunoreactivity in human normal peripheral mononuclear cells and lymphoid and myeloid malignancies.

A. Clark, R. Buzzetti, P. Lavender, 1989, The Journal of clinical investigation.

Interaction of the melanocortin 2 receptor with nucleoporin 50: evidence for a novel pathway between a G‐protein‐coupled receptor and the nucleus

H. Storr, A. Clark, M. Doufexis, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Human small cell lung cancer cell lines expressing the proopiomelanocortin gene have aberrant glucocorticoid receptor function.

Julian R. E. Davis, D. Ray, A. Clark, 1994, The Journal of clinical investigation.

In vitro and in vivo analysis of the processing and fate of the peptide products of the short proopiomelanocortin mRNA.

A. Clark, M. Johnson, L. Rees, 1990, Molecular endocrinology.

ACTH Antagonists

A. Clark, Li Chan, J. Jerman, 2016, Front. Endocrinol..

7 Ectopic hormone production

A. Clark, 1988 .

The mouse adrenocorticotropin receptor gene: cloning and characterization of its promoter and evidence for a role for the orphan nuclear receptor steroidogenic factor 1.

G. Pullinger, A. Clark, F. Cammas, 1997, Molecular endocrinology.

Linkage of the angiotensinogen gene to essential hypertension.

P. Munroe, M. Caulfield, M. Farrall, 1994, The New England journal of medicine.

Epidermal growth factor regulates the expression of its own receptor.

I. Pastan, S. Ishii, G. Merlino, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Adrenocorticotropin receptor gene mutations in familial glucocorticoid deficiency: relationships with clinical features in four families.

J. Toppari, K. Näntö-Salonen, A. Clark, 1995, The Journal of clinical endocrinology and metabolism.

Amplification and enhanced expression of the epidermal growth factor receptor gene in A431 human carcinoma cells.

Y H Xu, I. Pastan, S. Ishii, 1984, Science.

Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells

B. Roe, R. Wilson, I. Pastan, 1984, Nature.

Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells

Y H Xu, B. Roe, I. Pastan, 1985, Molecular and cellular biology.

The proximal milk protein binding factor binding site is required for the prolactin responsiveness of the sheep β-lactoglobulin promoter in Chinese hamster ovary cells

C. Watson, T. Burdon, A. Clark, 1995, Molecular and Cellular Endocrinology.

Heterogeneity in the molecular basis of ACTH resistance syndrome.

M. de Castro, A. Moreira, A. Clark, 2008, European journal of endocrinology.

ACTH resistance syndromes.

A. Clark, A. Huebner, A Huebner, 1999, Journal of pediatric endocrinology & metabolism : JPEM.

Luteinizing hormone (LH)-responsive Cushing's syndrome: the demonstration of LH receptor messenger ribonucleic acid in hyperplastic adrenal cells, which respond to chorionic gonadotropin and serotonin agonists in vitro.

H. Bonjer, S. Lamberts, F. de Jong, 2003, The Journal of clinical endocrinology and metabolism.

Cloning, characterization and expression of a functional mouse ACTH receptor.

A. Clark, F. Cammas, S. Kapas, 1995, Biochemical and biophysical research communications.

The Melanocortin-2 Receptor in Normal Adrenocortical Function and Familial Adrenocorticotropic Hormone Resistance

A. Clark, 2000 .

Identification of the sites of expression of triple a syndrome mRNA in the rat using in situ hybridisation

G. Michael, J. Priestley, H. Storr, 2005, Neuroscience.

Familial glucocorticoid deficiency: one syndrome, but more than one gene

A. Clark, F. Cammas, S. Kapas, 1997, Journal of Molecular Medicine.

Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans.

M. Caulfield, M. Farrall, J. Newell-Price, 1995, The Journal of clinical investigation.

Functional characterization of naturally occurring mutations of the human adrenocorticotropin receptor: poor correlation of phenotype and genotype.

G. Pullinger, A. Clark, A. Huebner, 1999, The Journal of clinical endocrinology and metabolism.

Functional characterization of the cloned human ACTH receptor: impaired responsiveness of a mutant receptor in familial glucocorticoid deficiency.

A. Clark, D. Grant, S. Kapas, 1993, Biochemical and biophysical research communications.

Glucocorticoid receptor structure and function in glucocorticoid-resistant small cell lung carcinoma cells.

Julian R. E. Davis, D. Ray, A. Clark, 1996, Cancer research.

Pro-opiomelanocortin gene expression and peptide secretion in human small-cell lung cancer cell lines.

M. F. Stewart, W. Farrell, A. Clark, 1989, Journal of molecular endocrinology.

Essential hypertension in African Caribbeans associates with a variant of the beta2-adrenoceptor.

M. Caulfield, A. Clark, P. Kotanko, 1997, Hypertension.

Defective glucocorticoid regulation of proopiomelanocortin gene expression and peptide secretion in a small cell lung cancer cell line.

M. F. Stewart, W. Farrell, A. Clark, 1990, The Journal of clinical endocrinology and metabolism.

Angiotensinogen in human essential hypertension.

M. Caulfield, M. Farrall, J. Newell-Price, 1996, Hypertension.

A DNA variant at the angiotensin-converting enzyme gene locus associates with coronary artery disease in the Caerphilly Heart Study.

M. Caulfield, D. Galton, A. Clark, 1995, Circulation.

A monoclonal antibody to a conserved sequence in the extracellular domain recognizes the angiotensin II AT1 receptor in mammalian target tissues.

A. Clark, J. Hinson, J. Puddefoot, 1993, Journal of molecular endocrinology.

Agonist and receptor binding properties of adrenocorticotropin peptides using the cloned mouse adrenocorticotropin receptor expressed in a stably transfected HeLa cell line.

A. Clark, F. Cammas, S. Kapas, 1996, Endocrinology.

Comparison of COS cell transfected AT1A and AT1B angiotensin II receptors and angiotensin II receptor isoforms in rat tissues using isoelectric focusing.

E. Jiménez, M. Montiel, A. Clark, 1993, Biochemical and biophysical research communications.

Cloning of bovine preproadrenomedullin and inhibition of its basal expression in vascular endothelial cells by staurosporine.

E. Wood, A. Clark, S. Barker, 1998, Life sciences.

Expression of the mouse ACTH receptor gene and characterisation of its promoter.

A. Clark, F. Cammas, S. Kapas, 1996, Endocrine research.

Exclusion of the adrenocorticotropin (ACTH) receptor (MC2R) locus in some families with ACTH resistance but no mutations of the MC2R coding sequence (familial glucocorticoid deficiency type 2).

E. Génin, A. Clark, D. Naville, 1998, The Journal of clinical endocrinology and metabolism.

The molecular pathogenesis of ACTH insensitivity syndromes.

L. Metherell, A. Clark, L. Elias, 2001, Annales d'endocrinologie.

The CpG island promoter of the human proopiomelanocortin gene is methylated in nonexpressing normal tissue and tumors and represses expression.

J. Newell-Price, A. Clark, P. King, 2001, Molecular endocrinology.

University of Huddersfield Repository Epigenetic modification of the renin-angiotensin system in the fetal programming of hypertension

A. Clark, I. Bogdarina, P. King, 2022 .

Epigenetic Modification of the Renin-Angiotensin System in the Fetal Programming of Print

Simon J. M. Welham, A. Clark, I. Bogdarina, 2007 .

Defects of Adrenocorticotropin Action on the Adrenal

A. Clark, A. Huebner, J. L. Franklin, 2000 .

Variable methylation of the 5'-flanking DNA of the human pro-opiomelanocortin gene.

A. Clark, G. Besser, L. Rees, 1991, Journal of Molecular Endocrinology.

Expression of pro-opiomelanocortin gene and quantification of adrenocorticotropic hormone-like immunoreactivity in human normal peripheral mononuclear cells and lymphoid and myeloid malignancies.

A. Clark, R. Buzzetti, P. Lavender, 1989, The Journal of clinical investigation.

Expression of Adrenomedullin ( ADM ) and Its Binding Sites in the Rat Uterus : Increased Number of Binding Sites and ADM Messenger Ribonucleic Acid in 20-Day Pregnant Rats Compared with Nonpregnant Rats *

C. Austin, M. Ghatei, A. Clark, 1997 .

ACTH Antagonists

J. Newell-Price, A. Clark, Li Chan, 2016, Front. Endocrinol..