D. T. Hung

发表

"Mirror image" antagonists of thrombin-induced platelet activation based on thrombin receptor structure.

V. Wheaton, C. Esmon, S. Coughlin, 1992, The Journal of clinical investigation.

Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor

S. Coughlin, D. T. Hung, T. Vu, 1992, The Journal of cell biology.

HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides.

D. Wiley, D. Garboczi, D. T. Hung, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function.

V. Wheaton, C. Turck, S. Coughlin, 1992, The Journal of biological chemistry.

The cloned platelet thrombin receptor couples to at least two distinct effectors to stimulate phosphoinositide hydrolysis and inhibit adenylyl cyclase.

S. Coughlin, Y. Wong, D. T. Hung, 1992, The Journal of biological chemistry.

Domains specifying thrombin–receptor interaction

V. Wheaton, S. Coughlin, D. T. Hung, 1991, Nature.

Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation.

V. Wheaton, S. Coughlin, D. T. Hung, 1992, The Journal of clinical investigation.

Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide.

Vikas Dixit, Emma McCullagh, D. T. Hung, 2016, Bioorganic & medicinal chemistry letters.

Expression Cloning and Characterization of a Functional Thrombin Receptor Reveals a Novel Proteolytic Mechanism of Receptor Activation

V. Wheaton, S. Coughlin, D. T. Hung, 1992, Seminars in thrombosis and hemostasis.

Characterization of a functional thrombin receptor. Issues and opportunities.

V. Wheaton, S. Coughlin, D. T. Hung, 1992, The Journal of clinical investigation.

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

V. Wheaton, S. Coughlin, D. T. Hung, 1991, Cell.

Targeting prostate cancer with compounds possessing dual activity as androgen receptor antagonists and HDAC6 inhibitors.

Devleena Shivakumar, J. Lindquist, D. T. Hung, 2016, Bioorganic & medicinal chemistry letters.

Dual Inhibition of Bruton’s Tyrosine Kinase and Phosphoinositide-3-Kinase p110δ as a Therapeutic Approach to Treat Non-Hodgkin’s B Cell Malignancies

Emma McCullagh, D. T. Hung, S. Bernales, 2017, The Journal of Pharmacology and Experimental Therapeutics.

Novel 3-methylindoline inhibitors of EZH2: Design, synthesis and SAR.

D. Severance, D. T. Hung, S. Bernales, 2017, Bioorganic & medicinal chemistry letters.